Drosophila melanogaster

0 known processes

ATPCL (Dmel_CG8322)

ATP citrate lyase

(Aliases: BcDNA:LD21334,CG8322,n(2)k09217,l(2)k09217,anon-WO0140519.179,Dmel\CG8322,DmATPCL,l(2)01466)

ATPCL biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
lateral inhibition GO:0046331 206 0.175
cell cell signaling involved in cell fate commitment GO:0045168 210 0.140
positive regulation of macromolecule biosynthetic process GO:0010557 283 0.130
carboxylic acid metabolic process GO:0019752 92 0.109
Rat
organic acid metabolic process GO:0006082 103 0.091
Rat
regulation of transcription from rna polymerase ii promoter GO:0006357 378 0.089
oxoacid metabolic process GO:0043436 103 0.079
Rat
positive regulation of nucleobase containing compound metabolic process GO:0045935 332 0.076
response to abiotic stimulus GO:0009628 341 0.073
endocytosis GO:0006897 310 0.063
positive regulation of cellular biosynthetic process GO:0031328 316 0.062
vesicle mediated transport GO:0016192 381 0.062
organic substance catabolic process GO:1901575 308 0.056
positive regulation of nitrogen compound metabolic process GO:0051173 354 0.056
positive regulation of rna biosynthetic process GO:1902680 266 0.056
positive regulation of macromolecule metabolic process GO:0010604 405 0.055
transcription from rna polymerase ii promoter GO:0006366 368 0.054
positive regulation of nucleic acid templated transcription GO:1903508 266 0.053
cellular response to abiotic stimulus GO:0071214 58 0.051
cellular amino acid metabolic process GO:0006520 61 0.051
post embryonic appendage morphogenesis GO:0035120 385 0.050
small molecule metabolic process GO:0044281 305 0.050
Rat
positive regulation of response to stimulus GO:0048584 323 0.048
positive regulation of rna metabolic process GO:0051254 271 0.047
response to radiation GO:0009314 155 0.045
negative regulation of gene expression GO:0010629 387 0.044
detection of external stimulus GO:0009581 66 0.043
positive regulation of gene expression GO:0010628 290 0.043
phagocytosis GO:0006909 215 0.043
appendage development GO:0048736 401 0.043
positive regulation of cell communication GO:0010647 250 0.042
imaginal disc derived appendage development GO:0048737 399 0.041
cellular catabolic process GO:0044248 372 0.041
dorsal ventral pattern formation GO:0009953 133 0.041
regulation of localization GO:0032879 275 0.040
negative regulation of rna metabolic process GO:0051253 251 0.040
detection of stimulus GO:0051606 156 0.039
detection of visible light GO:0009584 38 0.039
regulation of cellular response to stress GO:0080135 89 0.038
response to organic substance GO:0010033 284 0.038
positive regulation of transcription from rna polymerase ii promoter GO:0045944 204 0.038
organic substance transport GO:0071702 257 0.037
catabolic process GO:0009056 409 0.036
positive regulation of biosynthetic process GO:0009891 316 0.036
eye development GO:0001654 323 0.035
body morphogenesis GO:0010171 2 0.035
positive regulation of signaling GO:0023056 243 0.034
regulation of cellular ketone metabolic process GO:0010565 3 0.034
negative regulation of macromolecule biosynthetic process GO:0010558 270 0.034
imaginal disc derived wing morphogenesis GO:0007476 337 0.034
regulation of response to stress GO:0080134 200 0.034
wing disc morphogenesis GO:0007472 344 0.034
imaginal disc derived appendage morphogenesis GO:0035114 395 0.034
male gamete generation GO:0048232 201 0.034
organonitrogen compound metabolic process GO:1901564 318 0.033
response to lipopolysaccharide GO:0032496 4 0.033
protein modification process GO:0036211 438 0.033
establishment of localization in cell GO:0051649 402 0.033
regulation of cellular amine metabolic process GO:0033238 3 0.032
developmental maturation GO:0021700 172 0.032
response to light stimulus GO:0009416 124 0.032
amine metabolic process GO:0009308 12 0.032
compound eye development GO:0048749 307 0.032
g protein coupled receptor signaling pathway GO:0007186 136 0.032
cellular response to dna damage stimulus GO:0006974 223 0.032
negative regulation of transcription dna templated GO:0045892 237 0.030
regionalization GO:0003002 416 0.030
cellular ketone metabolic process GO:0042180 24 0.029
regulation of multicellular organismal development GO:2000026 414 0.029
spermatid differentiation GO:0048515 114 0.029
cellular macromolecule catabolic process GO:0044265 136 0.029
organelle fission GO:0048285 340 0.029
positive regulation of signal transduction GO:0009967 223 0.029
detection of light stimulus GO:0009583 58 0.028
regulation of cellular amino acid metabolic process GO:0006521 0 0.028
metal ion homeostasis GO:0055065 44 0.028
negative regulation of cellular macromolecule biosynthetic process GO:2000113 267 0.028
biological adhesion GO:0022610 138 0.028
negative regulation of nitrogen compound metabolic process GO:0051172 265 0.028
forebrain development GO:0030900 2 0.028
cellular response to molecule of bacterial origin GO:0071219 3 0.028
camera type eye development GO:0043010 4 0.028
lipid localization GO:0010876 54 0.028
negative regulation of nucleobase containing compound metabolic process GO:0045934 261 0.028
epithelial cell differentiation GO:0030855 322 0.028
appendage morphogenesis GO:0035107 397 0.028
negative regulation of rna biosynthetic process GO:1902679 240 0.027
ion transport GO:0006811 145 0.027
tissue morphogenesis GO:0048729 297 0.027
cytoskeleton dependent cytokinesis GO:0061640 81 0.027
pigmentation GO:0043473 75 0.027
regulation of cell cycle GO:0051726 291 0.027
cellular response to light stimulus GO:0071482 37 0.027
spermatogenesis GO:0007283 200 0.027
cell projection assembly GO:0030031 94 0.026
single organism catabolic process GO:0044712 228 0.026
morphogenesis of an epithelium GO:0002009 276 0.026
mesenchymal cell differentiation GO:0048762 1 0.026
macromolecule catabolic process GO:0009057 161 0.026
positive regulation of transcription dna templated GO:0045893 266 0.026
single organism biosynthetic process GO:0044711 206 0.026
Rat
negative regulation of cellular biosynthetic process GO:0031327 277 0.026
negative regulation of biosynthetic process GO:0009890 277 0.025
homeostatic process GO:0042592 199 0.025
cellular response to lipopolysaccharide GO:0071222 3 0.025
cellular response to radiation GO:0071478 52 0.025
carbohydrate metabolic process GO:0005975 82 0.024
androgen metabolic process GO:0008209 1 0.024
cellular component assembly involved in morphogenesis GO:0010927 151 0.024
regulation of mitotic cell cycle GO:0007346 190 0.024
gland development GO:0048732 191 0.024
cell maturation GO:0048469 144 0.024
lipopolysaccharide mediated signaling pathway GO:0031663 1 0.024
nuclear division GO:0000280 332 0.024
exocrine system development GO:0035272 162 0.024
taxis GO:0042330 304 0.024
single organism carbohydrate metabolic process GO:0044723 72 0.024
intracellular signal transduction GO:0035556 300 0.023
eye morphogenesis GO:0048592 260 0.023
innate immune response GO:0045087 144 0.023
regulation of cellular catabolic process GO:0031329 157 0.023
detection of chemical stimulus GO:0009593 93 0.023
phototransduction visible light GO:0007603 27 0.023
negative regulation of cell cycle phase transition GO:1901988 103 0.023
response to glucose GO:0009749 2 0.023
kidney development GO:0001822 3 0.023
wing disc pattern formation GO:0035222 66 0.023
positive regulation of intracellular signal transduction GO:1902533 116 0.023
positive regulation of lipid storage GO:0010884 4 0.022
negative regulation of nucleic acid templated transcription GO:1903507 240 0.022
negative regulation of mitotic cell cycle GO:0045930 109 0.022
positive regulation of cellular amino acid metabolic process GO:0045764 0 0.022
muscle structure development GO:0061061 224 0.022
regulation of cell cycle phase transition GO:1901987 130 0.022
proteolysis GO:0006508 192 0.022
regulation of mitotic cell cycle phase transition GO:1901990 130 0.022
organelle assembly GO:0070925 198 0.022
negative regulation of signaling GO:0023057 219 0.021
response to other organism GO:0051707 293 0.021
developmental growth GO:0048589 280 0.021
cellular response to chemical stimulus GO:0070887 199 0.021
positive regulation of cellular amine metabolic process GO:0033240 0 0.021
protein localization GO:0008104 284 0.021
protein catabolic process GO:0030163 101 0.021
growth GO:0040007 359 0.021
programmed cell death GO:0012501 257 0.021
telencephalon development GO:0021537 2 0.021
cellular protein modification process GO:0006464 438 0.021
cellular amine metabolic process GO:0044106 12 0.021
regulation of intracellular signal transduction GO:1902531 236 0.021
sodium dependent phosphate transport GO:0044341 2 0.021
regulation of pathway restricted smad protein phosphorylation GO:0060393 1 0.021
multi organism behavior GO:0051705 175 0.021
positive regulation of cell motility GO:2000147 3 0.020
regulation of cell cycle process GO:0010564 181 0.020
cellular macromolecule localization GO:0070727 220 0.020
tube morphogenesis GO:0035239 191 0.020
localization of cell GO:0051674 257 0.020
response to oxygen containing compound GO:1901700 200 0.020
mitotic cytokinesis GO:0000281 50 0.020
protein transport GO:0015031 155 0.020
regulation of cellular protein metabolic process GO:0032268 243 0.020
negative regulation of mitotic cell cycle phase transition GO:1901991 103 0.020
regulation of catabolic process GO:0009894 170 0.020
cell cycle phase transition GO:0044770 140 0.019
cell migration GO:0016477 238 0.019
anatomical structure homeostasis GO:0060249 97 0.019
cell division GO:0051301 248 0.019
detection of abiotic stimulus GO:0009582 66 0.019
actin filament based process GO:0030029 220 0.019
gland morphogenesis GO:0022612 145 0.019
response to monosaccharide GO:0034284 4 0.019
phosphorylation GO:0016310 294 0.018
spermatid development GO:0007286 98 0.018
ubiquitin dependent protein catabolic process GO:0006511 78 0.018
salivary gland morphogenesis GO:0007435 145 0.018
regulation of cellular component biogenesis GO:0044087 201 0.018
developmental pigmentation GO:0048066 68 0.018
cell motility GO:0048870 251 0.018
regulation of molecular function GO:0065009 217 0.018
cilium morphogenesis GO:0060271 39 0.018
cellular response to organic substance GO:0071310 132 0.018
phototransduction GO:0007602 52 0.018
negative regulation of response to stimulus GO:0048585 258 0.018
epithelial cell development GO:0002064 274 0.018
connective tissue development GO:0061448 3 0.018
posttranscriptional regulation of gene expression GO:0010608 145 0.018
dendrite development GO:0016358 204 0.018
muscle cell differentiation GO:0042692 103 0.018
negative regulation of cellular metabolic process GO:0031324 382 0.018
enzyme linked receptor protein signaling pathway GO:0007167 179 0.018
death GO:0016265 284 0.017
immune system process GO:0002376 347 0.017
establishment of protein localization GO:0045184 163 0.017
regulation of notch signaling pathway GO:0008593 100 0.017
alpha amino acid metabolic process GO:1901605 20 0.017
carbohydrate derivative metabolic process GO:1901135 217 0.017
chromosome organization GO:0051276 360 0.017
regulation of transport GO:0051049 181 0.017
positive regulation of transport GO:0051050 92 0.017
columnar cuboidal epithelial cell differentiation GO:0002065 256 0.017
regulation of epithelial cell proliferation GO:0050678 4 0.017
columnar cuboidal epithelial cell development GO:0002066 249 0.017
mitotic cell cycle phase transition GO:0044772 138 0.017
positive regulation of catalytic activity GO:0043085 118 0.017
compound eye photoreceptor development GO:0042051 78 0.017
photoreceptor cell development GO:0042461 96 0.017
chemical homeostasis GO:0048878 92 0.017
regulation of i kappab kinase nf kappab signaling GO:0043122 2 0.017
salivary gland development GO:0007431 162 0.017
antimicrobial humoral response GO:0019730 99 0.017
chemotaxis GO:0006935 249 0.017
muscle organ development GO:0007517 127 0.017
heterocycle catabolic process GO:0046700 166 0.017
cellular protein catabolic process GO:0044257 83 0.016
dendrite morphogenesis GO:0048813 199 0.016
proteolysis involved in cellular protein catabolic process GO:0051603 83 0.016
autophagic cell death GO:0048102 83 0.016
phosphatidylethanolamine metabolic process GO:0046337 1 0.016
nephron morphogenesis GO:0072028 3 0.016
eye photoreceptor cell differentiation GO:0001754 145 0.016
protein modification by small protein removal GO:0070646 28 0.016
modification dependent protein catabolic process GO:0019941 78 0.016
histolysis GO:0007559 102 0.016
regulation of sequestering of triglyceride GO:0010889 3 0.016
pigment metabolic process involved in developmental pigmentation GO:0043324 33 0.016
somatic muscle development GO:0007525 66 0.016
sensory organ morphogenesis GO:0090596 260 0.016
regulation of protein metabolic process GO:0051246 256 0.016
developmental programmed cell death GO:0010623 138 0.016
apoptotic process GO:0006915 159 0.016
neurological system process GO:0050877 358 0.016
striated muscle cell differentiation GO:0051146 90 0.016
cell death GO:0008219 279 0.016
regulation of cell differentiation GO:0045595 302 0.016
positive regulation of cell migration GO:0030335 2 0.016
imaginal disc pattern formation GO:0007447 91 0.016
mitotic g2 dna damage checkpoint GO:0007095 69 0.016
mitotic spindle organization GO:0007052 220 0.015
single organism intracellular transport GO:1902582 207 0.015
protein hydroxylation GO:0018126 1 0.015
eye pigment metabolic process GO:0042441 33 0.015
peptidyl amino acid modification GO:0018193 105 0.015
kidney epithelium development GO:0072073 3 0.015
organonitrogen compound biosynthetic process GO:1901566 117 0.015
cell adhesion GO:0007155 136 0.015
sterol homeostasis GO:0055092 4 0.015
response to external biotic stimulus GO:0043207 293 0.015
protein complex assembly GO:0006461 200 0.015
kidney morphogenesis GO:0060993 3 0.015
regulation of cell death GO:0010941 173 0.015
negative regulation of cell cycle process GO:0010948 109 0.015
photoreceptor cell differentiation GO:0046530 170 0.015
phosphate ion transport GO:0006817 4 0.015
cranial nerve development GO:0021545 1 0.015
store operated calcium entry GO:0002115 3 0.015
intracellular protein transport GO:0006886 104 0.015
response to bacterium GO:0009617 198 0.015
cullin deneddylation GO:0010388 3 0.015
anterior posterior pattern specification GO:0009952 136 0.015
single organism cellular localization GO:1902580 180 0.015
single organism behavior GO:0044708 391 0.015
regulation of neurogenesis GO:0050767 158 0.015
compound eye photoreceptor cell differentiation GO:0001751 140 0.015
monocarboxylic acid metabolic process GO:0032787 29 0.015
Rat
locomotory behavior GO:0007626 176 0.015
ion homeostasis GO:0050801 55 0.015
tissue death GO:0016271 102 0.015
positive regulation of epithelial cell differentiation GO:0030858 1 0.015
salivary gland cell autophagic cell death GO:0035071 83 0.014
proteasomal protein catabolic process GO:0010498 59 0.014
limb morphogenesis GO:0035108 1 0.014
nephron epithelium development GO:0072009 3 0.014
response to organophosphorus GO:0046683 2 0.014
synapse organization GO:0050808 196 0.014
multicellular organismal aging GO:0010259 140 0.014
mushroom body development GO:0016319 70 0.014
neuron projection guidance GO:0097485 241 0.014
nitrogen compound transport GO:0071705 85 0.014
cellular response to biotic stimulus GO:0071216 4 0.014
negative regulation of multicellular organismal process GO:0051241 142 0.014
mesenchymal cell development GO:0014031 1 0.014
regulation of immune response GO:0050776 118 0.014
i kappab phosphorylation GO:0007252 3 0.014
axon guidance GO:0007411 233 0.014
cilium assembly GO:0042384 38 0.014
regulation of organelle organization GO:0033043 196 0.014
cell recognition GO:0008037 102 0.014
nucleobase containing small molecule metabolic process GO:0055086 174 0.014
protein modification by small protein conjugation or removal GO:0070647 106 0.014
inter male aggressive behavior GO:0002121 60 0.014
peptidyl proline modification GO:0018208 3 0.014
regulation of catalytic activity GO:0050790 185 0.014
nephron development GO:0072006 3 0.014
notch signaling pathway GO:0007219 120 0.014
stem cell differentiation GO:0048863 117 0.014
apoptotic process involved in morphogenesis GO:0060561 3 0.014
cellular response to mechanical stimulus GO:0071260 2 0.014
cytoplasmic transport GO:0016482 130 0.014
eye pigmentation GO:0048069 43 0.014
salivary gland histolysis GO:0035070 88 0.014
cellular protein localization GO:0034613 160 0.014
negative regulation of cell differentiation GO:0045596 143 0.014
cell proliferation GO:0008283 299 0.013
pigment biosynthetic process GO:0046148 36 0.013
compound eye morphogenesis GO:0001745 249 0.013
embryonic development via the syncytial blastoderm GO:0001700 148 0.013
pigment metabolic process GO:0042440 84 0.013
negative regulation of signal transduction GO:0009968 206 0.013
mitotic cell cycle checkpoint GO:0007093 88 0.013
skeletal muscle fiber development GO:0048741 3 0.013
defense response to bacterium GO:0042742 178 0.013
cytokinesis GO:0000910 90 0.013
protein targeting GO:0006605 64 0.013
regulation of anatomical structure size GO:0090066 163 0.013
negative regulation of developmental process GO:0051093 201 0.013
immune response regulating signaling pathway GO:0002764 2 0.013
respiratory system development GO:0060541 213 0.013
segmentation GO:0035282 207 0.013
deactivation of rhodopsin mediated signaling GO:0016059 17 0.013
embryonic axis specification GO:0000578 107 0.013
immune response GO:0006955 246 0.013
regulation of apoptotic process GO:0042981 130 0.013
hindbrain development GO:0030902 2 0.013
activation of innate immune response GO:0002218 4 0.013
regulation of lipid storage GO:0010883 22 0.013
monocarboxylic acid transport GO:0015718 3 0.013
cell surface receptor signaling pathway involved in heart development GO:0061311 3 0.013
limb development GO:0060173 1 0.013
positive regulation of sequestering of triglyceride GO:0010890 1 0.013
digestive tract development GO:0048565 149 0.013
protein complex biogenesis GO:0070271 201 0.013
negative regulation of cell cycle GO:0045786 116 0.013
oocyte dorsal ventral axis specification GO:0007310 34 0.013
regulation of cuticle pigmentation GO:0048079 16 0.013
endoderm formation GO:0001706 3 0.013
retina development in camera type eye GO:0060041 4 0.013
anterior posterior axis specification embryo GO:0008595 103 0.013
mitotic nuclear division GO:0007067 213 0.013
regulation of growth GO:0040008 233 0.013
immune effector process GO:0002252 98 0.013
embryonic morphogenesis GO:0048598 206 0.013
l glutamate import GO:0051938 1 0.013
detection of stimulus involved in sensory perception GO:0050906 92 0.013
cell fate determination GO:0001709 91 0.013
regulation of organ formation GO:0003156 3 0.013
modification dependent macromolecule catabolic process GO:0043632 79 0.013
cellular homeostasis GO:0019725 80 0.012
multi multicellular organism process GO:0044706 123 0.012
lipid metabolic process GO:0006629 121 0.012
Rat
detection of chemical stimulus involved in sensory perception GO:0050907 75 0.012
secretion GO:0046903 109 0.012
regulation of synaptic transmission GO:0050804 69 0.012
small gtpase mediated signal transduction GO:0007264 88 0.012
mesoderm development GO:0007498 78 0.012
tripartite regional subdivision GO:0007351 103 0.012
cholesterol transport GO:0030301 2 0.012
g2 dna damage checkpoint GO:0031572 69 0.012
regulation of nervous system development GO:0051960 248 0.012
regulation of programmed cell death GO:0043067 152 0.012
olfactory behavior GO:0042048 97 0.012
regulation of synapse organization GO:0050807 110 0.012
regulation of embryonic development GO:0045995 68 0.012
single organism nuclear import GO:1902593 51 0.012
ovarian follicle cell development GO:0030707 248 0.012
open tracheal system development GO:0007424 204 0.012
response to nutrient levels GO:0031667 114 0.012
positive regulation of peptidyl tyrosine phosphorylation GO:0050731 4 0.012
stress activated protein kinase signaling cascade GO:0031098 55 0.012
mating GO:0007618 120 0.012
mitotic g2 m transition checkpoint GO:0044818 70 0.012
intracellular protein transmembrane transport GO:0065002 4 0.012
mitotic dna damage checkpoint GO:0044773 74 0.012
transmembrane transport GO:0055085 139 0.012
regulation of response to external stimulus GO:0032101 115 0.012
cellular response to oxygen containing compound GO:1901701 79 0.012
establishment of protein localization to organelle GO:0072594 62 0.012
nucleobase containing compound catabolic process GO:0034655 165 0.012
protein maturation GO:0051604 71 0.012
positive regulation of catabolic process GO:0009896 105 0.012
myotube cell development GO:0014904 3 0.012
positive regulation of lipid metabolic process GO:0045834 4 0.012
wnt signaling pathway GO:0016055 98 0.012
response to oxygen levels GO:0070482 59 0.012
response to hexose GO:0009746 3 0.012
protein localization to nucleus GO:0034504 55 0.012
meiotic cell cycle GO:0051321 171 0.012
regulation of epithelial cell differentiation GO:0030856 4 0.012
cellular macromolecular complex assembly GO:0034622 153 0.012
dorsal ventral pattern formation imaginal disc GO:0007450 51 0.012
determination of adult lifespan GO:0008340 137 0.012
carbohydrate derivative biosynthetic process GO:1901137 85 0.012
chaeta morphogenesis GO:0008407 42 0.012
hematopoietic progenitor cell differentiation GO:0002244 1 0.012
pattern recognition receptor signaling pathway GO:0002221 2 0.012
germarium derived egg chamber formation GO:0007293 101 0.012
muscle attachment GO:0016203 36 0.012
ras protein signal transduction GO:0007265 88 0.012
reproductive behavior GO:0019098 122 0.012
benzene containing compound metabolic process GO:0042537 3 0.012
chromatin modification GO:0016568 147 0.012
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 65 0.012
response to temperature stimulus GO:0009266 106 0.011
response to hypoxia GO:0001666 53 0.011
eye photoreceptor cell development GO:0042462 81 0.011
positive regulation of phosphorus metabolic process GO:0010562 139 0.011
imaginal disc derived wing vein specification GO:0007474 48 0.011
regulation of anatomical structure morphogenesis GO:0022603 242 0.011
immune response activating signal transduction GO:0002757 2 0.011
jak stat cascade GO:0007259 49 0.011
cellular carbohydrate catabolic process GO:0044275 2 0.011
response to endogenous stimulus GO:0009719 119 0.011
nephron tubule morphogenesis GO:0072078 3 0.011
amide biosynthetic process GO:0043604 42 0.011
secretion by cell GO:0032940 101 0.011
cellularization GO:0007349 90 0.011
carbohydrate derivative catabolic process GO:1901136 118 0.011
nephron tubule development GO:0072080 3 0.011
aging GO:0007568 143 0.011
protein localization to organelle GO:0033365 82 0.011
long term memory GO:0007616 62 0.011
axonogenesis GO:0007409 290 0.011
secondary metabolic process GO:0019748 75 0.011
negative regulation of cellular protein metabolic process GO:0032269 85 0.011
ethanolamine containing compound metabolic process GO:0042439 4 0.011
regulation of organ morphogenesis GO:2000027 78 0.011
brain development GO:0007420 120 0.011
embryonic pattern specification GO:0009880 174 0.011
extracellular structure organization GO:0043062 46 0.011
regulation of rhodopsin mediated signaling pathway GO:0022400 17 0.011
cellular cation homeostasis GO:0030003 38 0.011
peptidyl lysine modification GO:0018205 57 0.011
negative regulation of gene expression epigenetic GO:0045814 77 0.011
synaptic transmission GO:0007268 288 0.011
positive regulation of calcium ion transport GO:0051928 4 0.011
fusome organization GO:0045478 13 0.011
regulation of wnt signaling pathway GO:0030111 68 0.011
negative regulation of immune system process GO:0002683 50 0.011
neuromuscular junction development GO:0007528 149 0.011
negative regulation of nervous system development GO:0051961 92 0.011
protein import GO:0017038 55 0.011
positive regulation of i kappab kinase nf kappab signaling GO:0043123 1 0.011
regulation of chitin based cuticle tanning GO:0007564 14 0.011
purine ribonucleotide metabolic process GO:0009150 145 0.011
establishment or maintenance of polarity of follicular epithelium GO:0016334 26 0.011
macromolecular complex assembly GO:0065003 256 0.011
rna processing GO:0006396 147 0.011
cellular response to ethanol GO:0071361 4 0.011
chromatin silencing GO:0006342 76 0.011
nuclear transport GO:0051169 72 0.011
regulation of proteolysis GO:0030162 87 0.011
regulation of multi organism process GO:0043900 131 0.011
regulation of establishment of protein localization GO:0070201 61 0.011
estrogen metabolic process GO:0008210 1 0.011
cell cycle checkpoint GO:0000075 95 0.011
formation of anatomical boundary GO:0048859 37 0.010
regulation of histone deacetylation GO:0031063 2 0.010
regulation of cell shape GO:0008360 113 0.010
positive regulation of molecular function GO:0044093 136 0.010
cuticle pigmentation GO:0048067 22 0.010
hormone catabolic process GO:0042447 3 0.010
endomembrane system organization GO:0010256 119 0.010
response to oxidative stress GO:0006979 86 0.010
neutral lipid biosynthetic process GO:0046460 2 0.010
lipid storage GO:0019915 38 0.010
peptidyl threonine phosphorylation GO:0018107 2 0.010
morphogenesis of embryonic epithelium GO:0016331 94 0.010
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 54 0.010
defense response to other organism GO:0098542 225 0.010
mesodermal cell migration GO:0008078 7 0.010
regulation of intracellular transport GO:0032386 64 0.010
regulation of lipid transport GO:0032368 3 0.010
positive regulation of phosphorylation GO:0042327 87 0.010
epiboly involved in wound healing GO:0090505 2 0.010
humoral immune response GO:0006959 117 0.010
aromatic compound catabolic process GO:0019439 166 0.010
molting cycle chitin based cuticle GO:0007591 56 0.010
response to organic cyclic compound GO:0014070 89 0.010

ATPCL disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.057
disease of metabolism DOID:0014667 0 0.044
carbohydrate metabolism disease DOID:0050013 0 0.044
glucose metabolism disease DOID:4194 0 0.044
acquired metabolic disease DOID:0060158 0 0.044
diabetes mellitus DOID:9351 0 0.019
type 2 diabetes mellitus DOID:9352 0 0.019
inherited metabolic disorder DOID:655 0 0.018
nervous system disease DOID:863 0 0.018
central nervous system disease DOID:331 0 0.013
neurodegenerative disease DOID:1289 0 0.013
musculoskeletal system disease DOID:17 0 0.013
cardiovascular system disease DOID:1287 0 0.011
urinary system disease DOID:18 0 0.010
cancer DOID:162 0 0.010
disease of cellular proliferation DOID:14566 0 0.010
organ system cancer DOID:0050686 0 0.010