Drosophila melanogaster

21 known processes

Ef2b (Dmel_CG2238)

Elongation factor 2b

(Aliases: Dmel\CG2238,CG2238,Ef2,anon-EST:Liang-1.44,clone 1.44,EF-2,EF-2b,EF2,eEF2)

Ef2b biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
mitotic spindle elongation GO:0000022 81 0.942
mitotic spindle organization GO:0007052 220 0.912
centrosome organization GO:0051297 163 0.875
centrosome duplication GO:0051298 121 0.861
translation GO:0006412 69 0.855
Human Mouse
spindle elongation GO:0051231 83 0.812
spindle organization GO:0007051 253 0.779
microtubule organizing center organization GO:0031023 168 0.732
centrosome cycle GO:0007098 137 0.690
death GO:0016265 284 0.607
Worm
cell death GO:0008219 279 0.575
Worm
ribosomal large subunit biogenesis GO:0042273 1 0.525
programmed cell death GO:0012501 257 0.496
Worm
small molecule metabolic process GO:0044281 305 0.347
Mouse
cytoplasmic translation GO:0002181 0 0.325
apoptotic process GO:0006915 159 0.242
Worm
cell motility GO:0048870 251 0.187
aging GO:0007568 143 0.159
Worm
embryo development ending in birth or egg hatching GO:0009792 152 0.159
Worm
response to organic substance GO:0010033 284 0.153
regulation of cell proliferation GO:0042127 163 0.150
multicellular organismal aging GO:0010259 140 0.120
Worm
regulation of cell death GO:0010941 173 0.114
posttranscriptional regulation of gene expression GO:0010608 145 0.113
Human
regulation of mitotic cell cycle GO:0007346 190 0.111
organelle assembly GO:0070925 198 0.105
determination of adult lifespan GO:0008340 137 0.085
Worm
cell proliferation GO:0008283 299 0.084
male gamete generation GO:0048232 201 0.082
regulation of translation GO:0006417 56 0.082
Human
ribonucleoprotein complex subunit organization GO:0071826 28 0.079
growth GO:0040007 359 0.079
Worm
gonad development GO:0008406 50 0.078
Worm
nucleoside catabolic process GO:0009164 112 0.077
Mouse
regulation of cell cycle process GO:0010564 181 0.075
ribonucleotide catabolic process GO:0009261 109 0.072
Mouse
regulation of cell cycle GO:0051726 291 0.071
endocytosis GO:0006897 310 0.070
ribonucleotide metabolic process GO:0009259 145 0.069
Mouse
negative regulation of cell cycle GO:0045786 116 0.062
nuclear division GO:0000280 332 0.062
nucleoside phosphate metabolic process GO:0006753 162 0.061
Mouse
cell migration GO:0016477 238 0.059
spermatid differentiation GO:0048515 114 0.055
spermatogenesis GO:0007283 200 0.053
regulation of programmed cell death GO:0043067 152 0.053
purine containing compound metabolic process GO:0072521 155 0.052
Mouse
regulation of anatomical structure size GO:0090066 163 0.052
oxoacid metabolic process GO:0043436 103 0.051
vesicle mediated transport GO:0016192 381 0.050
gene silencing by rna GO:0031047 57 0.050
carbohydrate derivative catabolic process GO:1901136 118 0.049
Mouse
transmembrane transport GO:0055085 139 0.049
gland development GO:0048732 191 0.049
rna interference GO:0016246 27 0.046
regulation of cellular component biogenesis GO:0044087 201 0.046
nucleoside triphosphate catabolic process GO:0009143 108 0.045
Mouse
meiotic nuclear division GO:0007126 151 0.045
purine nucleotide catabolic process GO:0006195 109 0.044
Mouse
localization of cell GO:0051674 257 0.043
response to wounding GO:0009611 94 0.042
gene silencing GO:0016458 138 0.042
regulation of protein metabolic process GO:0051246 256 0.041
Human
cytoplasm organization GO:0007028 64 0.041
nucleotide metabolic process GO:0009117 161 0.041
Mouse
larval development GO:0002164 104 0.040
Worm
neuron projection guidance GO:0097485 241 0.039
nucleobase containing compound catabolic process GO:0034655 165 0.038
Mouse
proteolysis GO:0006508 192 0.038
purine ribonucleotide metabolic process GO:0009150 145 0.038
Mouse
ribonucleoprotein complex assembly GO:0022618 23 0.038
regulation of cellular protein metabolic process GO:0032268 243 0.036
Human
organonitrogen compound metabolic process GO:1901564 318 0.036
Mouse
organelle fission GO:0048285 340 0.035
purine nucleotide metabolic process GO:0006163 146 0.035
Mouse
regulation of apoptotic process GO:0042981 130 0.035
dendrite morphogenesis GO:0048813 199 0.033
cellular catabolic process GO:0044248 372 0.032
Mouse
salivary gland development GO:0007431 162 0.032
histolysis GO:0007559 102 0.031
developmental programmed cell death GO:0010623 138 0.030
taxis GO:0042330 304 0.029
regulation of gene expression epigenetic GO:0040029 128 0.029
meiotic cell cycle GO:0051321 171 0.029
wound healing GO:0042060 75 0.028
cellularization GO:0007349 90 0.028
positive regulation of developmental process GO:0051094 143 0.028
response to abiotic stimulus GO:0009628 341 0.028
sex differentiation GO:0007548 81 0.028
Worm
negative regulation of cellular macromolecule biosynthetic process GO:2000113 267 0.028
developmental growth GO:0048589 280 0.028
ubiquitin dependent protein catabolic process GO:0006511 78 0.027
negative regulation of mitotic cell cycle GO:0045930 109 0.027
positive regulation of cell migration GO:0030335 2 0.027
reproductive system development GO:0061458 74 0.026
Worm
negative regulation of cellular biosynthetic process GO:0031327 277 0.026
phagocytosis GO:0006909 215 0.023
axon guidance GO:0007411 233 0.023
purine nucleoside triphosphate catabolic process GO:0009146 108 0.023
Mouse
negative regulation of cell cycle process GO:0010948 109 0.023
ribosome biogenesis GO:0042254 8 0.022
aromatic compound catabolic process GO:0019439 166 0.022
Mouse
exocrine system development GO:0035272 162 0.022
purine nucleoside catabolic process GO:0006152 112 0.021
Mouse
ribonucleoside triphosphate metabolic process GO:0009199 119 0.021
Mouse
catabolic process GO:0009056 409 0.021
Mouse
cytoplasmic transport GO:0016482 130 0.021
axon development GO:0061564 297 0.021
regulation of hydrolase activity GO:0051336 97 0.021
positive regulation of macromolecule metabolic process GO:0010604 405 0.021
Human
cellular protein modification process GO:0006464 438 0.021
response to monosaccharide GO:0034284 4 0.020
posttranscriptional gene silencing GO:0016441 46 0.020
protein complex biogenesis GO:0070271 201 0.020
regulation of immune system process GO:0002682 176 0.020
positive regulation of response to stimulus GO:0048584 323 0.020
regulation of growth GO:0040008 233 0.019
single organism biosynthetic process GO:0044711 206 0.019
brain development GO:0007420 120 0.019
mitotic nuclear division GO:0007067 213 0.018
regulation of endopeptidase activity GO:0052548 36 0.018
positive regulation of catalytic activity GO:0043085 118 0.018
cellular response to chemical stimulus GO:0070887 199 0.018
Zebrafish
macromolecular complex assembly GO:0065003 256 0.018
purine nucleoside metabolic process GO:0042278 127 0.018
Mouse
positive regulation of hydrolase activity GO:0051345 78 0.018
positive regulation of cellular catabolic process GO:0031331 95 0.017
innate immune response GO:0045087 144 0.017
heterocycle catabolic process GO:0046700 166 0.017
Mouse
negative regulation of biosynthetic process GO:0009890 277 0.017
carbohydrate derivative metabolic process GO:1901135 217 0.017
Mouse
negative regulation of cell death GO:0060548 81 0.017
positive regulation of nucleoside metabolic process GO:0045979 47 0.016
nucleobase containing small molecule metabolic process GO:0055086 174 0.016
Mouse
positive regulation of locomotion GO:0040017 8 0.016
negative regulation of developmental process GO:0051093 201 0.016
cellular protein localization GO:0034613 160 0.016
ion transport GO:0006811 145 0.016
negative regulation of cell differentiation GO:0045596 143 0.016
positive regulation of growth GO:0045927 75 0.016
maintenance of location GO:0051235 73 0.016
intracellular signal transduction GO:0035556 300 0.016
macromolecule catabolic process GO:0009057 161 0.016
negative regulation of cell cycle phase transition GO:1901988 103 0.016
salivary gland morphogenesis GO:0007435 145 0.016
autophagic cell death GO:0048102 83 0.016
negative regulation of cell communication GO:0010648 223 0.015
organic acid metabolic process GO:0006082 103 0.015
nucleotide catabolic process GO:0009166 109 0.015
Mouse
salivary gland histolysis GO:0035070 88 0.015
positive regulation of cell communication GO:0010647 250 0.015
apoptotic signaling pathway GO:0097190 27 0.015
regulation of catalytic activity GO:0050790 185 0.015
negative regulation of nucleotide catabolic process GO:0030812 1 0.015
purine nucleoside monophosphate metabolic process GO:0009126 50 0.015
meiotic cell cycle process GO:1903046 132 0.014
body morphogenesis GO:0010171 2 0.014
reproductive structure development GO:0048608 74 0.014
Worm
peptidyl amino acid modification GO:0018193 105 0.014
ribonucleoside triphosphate catabolic process GO:0009203 108 0.014
Mouse
negative regulation of mitotic cell cycle phase transition GO:1901991 103 0.014
rna localization GO:0006403 115 0.014
regulation of cell size GO:0008361 63 0.014
positive regulation of peptidase activity GO:0010952 29 0.014
negative regulation of gene expression GO:0010629 387 0.013
salivary gland cell autophagic cell death GO:0035071 83 0.013
proteolysis involved in cellular protein catabolic process GO:0051603 83 0.013
negative regulation of signal transduction GO:0009968 206 0.013
regulation of cellular response to oxidative stress GO:1900407 4 0.013
single organism catabolic process GO:0044712 228 0.013
Mouse
positive regulation of catabolic process GO:0009896 105 0.013
central nervous system development GO:0007417 201 0.013
regulation of embryonic development GO:0045995 68 0.012
organic cyclic compound catabolic process GO:1901361 168 0.012
Mouse
cell cycle g1 s phase transition GO:0044843 31 0.012
nucleoside phosphate catabolic process GO:1901292 110 0.012
Mouse
positive regulation of protein metabolic process GO:0051247 128 0.012
Human
development of primary sexual characteristics GO:0045137 50 0.012
Worm
ribose phosphate metabolic process GO:0019693 145 0.012
Mouse
ribonucleoprotein complex biogenesis GO:0022613 31 0.012
positive regulation of translation GO:0045727 12 0.012
Human
protein catabolic process GO:0030163 101 0.012
negative regulation of apoptotic process GO:0043066 63 0.012
single organism intracellular transport GO:1902582 207 0.012
metal ion homeostasis GO:0055065 44 0.011
divalent inorganic cation homeostasis GO:0072507 29 0.011
glycosyl compound metabolic process GO:1901657 127 0.011
Mouse
response to hexose GO:0009746 3 0.011
axonogenesis GO:0007409 290 0.011
cellular macromolecular complex assembly GO:0034622 153 0.011
response to oxygen containing compound GO:1901700 200 0.011
intracellular transport GO:0046907 228 0.011
dendrite development GO:0016358 204 0.011
spermatid development GO:0007286 98 0.011
tissue death GO:0016271 102 0.010
intrinsic apoptotic signaling pathway GO:0097193 16 0.010
positive regulation of cell motility GO:2000147 3 0.010
mitotic cell cycle phase transition GO:0044772 138 0.010
nitrogen compound transport GO:0071705 85 0.010
locomotory behavior GO:0007626 176 0.010
negative regulation of cellular component organization GO:0051129 108 0.010
negative regulation of response to oxidative stress GO:1902883 1 0.010
protein modification process GO:0036211 438 0.010

Ef2b disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.019