Drosophila melanogaster

7 known processes

Rlip (Dmel_CG11622)

Ral interacting protein

(Aliases: RLIP,CG11622,dRalBP,D-RLIP,dRlip,RhoGAP-93B3,dRLIP,Dmel\CG11622)

Rlip biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
spermatogenesis GO:0007283 200 0.175
vesicle mediated transport GO:0016192 381 0.108
negative regulation of macromolecule biosynthetic process GO:0010558 270 0.106
positive regulation of response to stimulus GO:0048584 323 0.093
death GO:0016265 284 0.081
catabolic process GO:0009056 409 0.080
Human Mouse
negative regulation of nitrogen compound metabolic process GO:0051172 265 0.079
programmed cell death GO:0012501 257 0.079
regulation of catabolic process GO:0009894 170 0.077
Human Mouse
establishment of localization in cell GO:0051649 402 0.077
chromosome organization GO:0051276 360 0.067
negative regulation of gene expression GO:0010629 387 0.060
male gamete generation GO:0048232 201 0.060
negative regulation of nucleic acid templated transcription GO:1903507 240 0.054
regulation of cell shape GO:0008360 113 0.052
negative regulation of transcription dna templated GO:0045892 237 0.049
locomotory behavior GO:0007626 176 0.049
mitotic nuclear division GO:0007067 213 0.049
immune system process GO:0002376 347 0.048
positive regulation of cell communication GO:0010647 250 0.047
phosphorylation GO:0016310 294 0.046
organelle assembly GO:0070925 198 0.046
negative regulation of cellular metabolic process GO:0031324 382 0.046
cell death GO:0008219 279 0.046
negative regulation of nucleobase containing compound metabolic process GO:0045934 261 0.046
positive regulation of gene expression GO:0010628 290 0.045
positive regulation of signal transduction GO:0009967 223 0.044
protein modification process GO:0036211 438 0.042
regulation of protein localization GO:0032880 76 0.041
cation homeostasis GO:0055080 51 0.040
negative regulation of biosynthetic process GO:0009890 277 0.040
macromolecule catabolic process GO:0009057 161 0.040
negative regulation of cellular macromolecule biosynthetic process GO:2000113 267 0.040
signal transduction by phosphorylation GO:0023014 107 0.039
positive regulation of signaling GO:0023056 243 0.039
cell adhesion GO:0007155 136 0.039
negative regulation of signaling GO:0023057 219 0.038
positive regulation of rna biosynthetic process GO:1902680 266 0.038
actin filament based process GO:0030029 220 0.037
sister chromatid segregation GO:0000819 92 0.035
positive regulation of nucleic acid templated transcription GO:1903508 266 0.033
regulation of phosphorylation GO:0042325 147 0.032
cellular response to light stimulus GO:0071482 37 0.032
regulation of transport GO:0051049 181 0.031
regionalization GO:0003002 416 0.031
single organism behavior GO:0044708 391 0.031
protein localization GO:0008104 284 0.031
proteolysis GO:0006508 192 0.030
cellular catabolic process GO:0044248 372 0.030
Human Mouse
multi organism behavior GO:0051705 175 0.030
cellular macromolecule localization GO:0070727 220 0.030
multi organism reproductive behavior GO:0044705 121 0.029
dna packaging GO:0006323 91 0.029
negative regulation of rna metabolic process GO:0051253 251 0.029
response to organic substance GO:0010033 284 0.029
intracellular signal transduction GO:0035556 300 0.029
Human Rat
epithelial cell development GO:0002064 274 0.028
protein phosphorylation GO:0006468 169 0.028
immune response regulating signaling pathway GO:0002764 2 0.028
cellular response to abiotic stimulus GO:0071214 58 0.028
regulation of apoptotic process GO:0042981 130 0.028
organonitrogen compound metabolic process GO:1901564 318 0.028
Human Mouse
actin filament organization GO:0007015 126 0.027
regulation of molecular function GO:0065009 217 0.027
Human Mouse
regulation of mapk cascade GO:0043408 92 0.027
regulation of phosphorus metabolic process GO:0051174 210 0.027
Human Mouse
appendage development GO:0048736 401 0.027
developmental programmed cell death GO:0010623 138 0.027
apoptotic process GO:0006915 159 0.027
mapk cascade GO:0000165 107 0.026
organic substance catabolic process GO:1901575 308 0.026
Human Mouse
morphogenesis of a polarized epithelium GO:0001738 93 0.026
single organism membrane organization GO:0044802 93 0.026
phagocytosis GO:0006909 215 0.026
ras protein signal transduction GO:0007265 88 0.025
positive regulation of biosynthetic process GO:0009891 316 0.025
positive regulation of rna metabolic process GO:0051254 271 0.025
detection of abiotic stimulus GO:0009582 66 0.025
regulation of microtubule cytoskeleton organization GO:0070507 41 0.024
mitotic sister chromatid segregation GO:0000070 87 0.024
negative regulation of signal transduction GO:0009968 206 0.024
regulation of protein metabolic process GO:0051246 256 0.024
detection of stimulus GO:0051606 156 0.024
immune response activating signal transduction GO:0002757 2 0.024
compound eye morphogenesis GO:0001745 249 0.024
detection of external stimulus GO:0009581 66 0.023
organic substance transport GO:0071702 257 0.023
imaginal disc derived appendage development GO:0048737 399 0.022
sterol homeostasis GO:0055092 4 0.022
protein complex biogenesis GO:0070271 201 0.022
regulation of localization GO:0032879 275 0.022
single organism catabolic process GO:0044712 228 0.022
Human Mouse
regulation of proteolysis GO:0030162 87 0.022
response to alcohol GO:0097305 95 0.022
regulation of anatomical structure size GO:0090066 163 0.022
membrane organization GO:0061024 112 0.021
eye morphogenesis GO:0048592 260 0.021
endomembrane system organization GO:0010256 119 0.021
cellular cation homeostasis GO:0030003 38 0.021
cellular nitrogen compound catabolic process GO:0044270 165 0.021
Human Mouse
wing disc morphogenesis GO:0007472 344 0.021
synaptic transmission GO:0007268 288 0.021
organophosphate catabolic process GO:0046434 112 0.020
Human Mouse
negative regulation of apoptotic process GO:0043066 63 0.020
nuclear division GO:0000280 332 0.020
anterior posterior pattern specification GO:0009952 136 0.020
positive regulation of immune response GO:0050778 63 0.020
negative regulation of developmental process GO:0051093 201 0.020
taxis GO:0042330 304 0.020
organic cyclic compound catabolic process GO:1901361 168 0.020
Human Mouse
endocytosis GO:0006897 310 0.020
negative regulation of cell death GO:0060548 81 0.020
transmembrane transport GO:0055085 139 0.020
multicellular organismal aging GO:0010259 140 0.020
eye photoreceptor cell development GO:0042462 81 0.020
cellular macromolecular complex assembly GO:0034622 153 0.019
regulation of phosphate metabolic process GO:0019220 210 0.019
Human Mouse
histolysis GO:0007559 102 0.019
cellular protein modification process GO:0006464 438 0.019
forebrain development GO:0030900 2 0.019
ribonucleotide catabolic process GO:0009261 109 0.019
Human Mouse
lipid metabolic process GO:0006629 121 0.019
heterocycle catabolic process GO:0046700 166 0.018
Human Mouse
ribonucleoside triphosphate metabolic process GO:0009199 119 0.018
Human Mouse
purine containing compound catabolic process GO:0072523 112 0.018
Human Mouse
notch signaling pathway GO:0007219 120 0.018
regulation of cell death GO:0010941 173 0.018
negative regulation of cell differentiation GO:0045596 143 0.018
salivary gland histolysis GO:0035070 88 0.018
anion transport GO:0006820 41 0.018
regulation of protein catabolic process GO:0042176 55 0.018
biological adhesion GO:0022610 138 0.018
negative regulation of cell communication GO:0010648 223 0.017
positive regulation of transcription dna templated GO:0045893 266 0.017
microtubule polymerization or depolymerization GO:0031109 39 0.017
actin cytoskeleton organization GO:0030036 206 0.017
regulation of cell cycle GO:0051726 291 0.017
camera type eye development GO:0043010 4 0.017
regulation of embryonic development GO:0045995 68 0.017
regulation of gene expression epigenetic GO:0040029 128 0.017
regulation of programmed cell death GO:0043067 152 0.017
intracellular transport GO:0046907 228 0.016
regulation of cellular response to stress GO:0080135 89 0.016
sensory organ morphogenesis GO:0090596 260 0.016
aromatic compound catabolic process GO:0019439 166 0.016
Human Mouse
cellular homeostasis GO:0019725 80 0.016
regulation of transcription from rna polymerase ii promoter GO:0006357 378 0.016
compound eye development GO:0048749 307 0.016
growth GO:0040007 359 0.016
dna metabolic process GO:0006259 227 0.016
response to oxygen containing compound GO:1901700 200 0.016
meiotic cell cycle process GO:1903046 132 0.015
chromosome segregation GO:0007059 157 0.015
enzyme linked receptor protein signaling pathway GO:0007167 179 0.015
autophagic cell death GO:0048102 83 0.015
germ line stem cell maintenance GO:0030718 50 0.015
macromolecular complex assembly GO:0065003 256 0.015
positive regulation of cellular biosynthetic process GO:0031328 316 0.015
regulation of intracellular signal transduction GO:1902531 236 0.015
Human Mouse
spermatid development GO:0007286 98 0.015
regulation of cellular protein metabolic process GO:0032268 243 0.015
nucleobase containing compound catabolic process GO:0034655 165 0.015
Human Mouse
positive regulation of transcription from rna polymerase ii promoter GO:0045944 204 0.015
cellular macromolecule catabolic process GO:0044265 136 0.015
salivary gland cell autophagic cell death GO:0035071 83 0.015
ion transport GO:0006811 145 0.014
plasma membrane organization GO:0007009 26 0.014
positive regulation of macromolecule metabolic process GO:0010604 405 0.014
regulation of mitosis GO:0007088 56 0.014
cell maturation GO:0048469 144 0.014
regulation of cell morphogenesis GO:0022604 163 0.014
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 116 0.014
positive regulation of nitrogen compound metabolic process GO:0051173 354 0.014
Human Mouse
insulin receptor signaling pathway GO:0008286 25 0.014
negative regulation of rna biosynthetic process GO:1902679 240 0.014
synapse organization GO:0050808 196 0.014
positive regulation of intracellular signal transduction GO:1902533 116 0.014
peptidyl threonine phosphorylation GO:0018107 2 0.014
positive regulation of molecular function GO:0044093 136 0.014
Human Mouse
regulation of hydrolase activity GO:0051336 97 0.014
Human Mouse
organelle fission GO:0048285 340 0.013
regulation of multicellular organismal development GO:2000026 414 0.013
single organism cellular localization GO:1902580 180 0.013
protein complex assembly GO:0006461 200 0.013
epithelial cell differentiation GO:0030855 322 0.013
negative regulation of multicellular organismal process GO:0051241 142 0.013
tissue morphogenesis GO:0048729 297 0.013
negative regulation of cellular biosynthetic process GO:0031327 277 0.013
female meiosis chromosome segregation GO:0016321 33 0.013
homeostatic process GO:0042592 199 0.013
organophosphate metabolic process GO:0019637 195 0.013
Human Mouse
cellular protein complex assembly GO:0043623 71 0.013
response to abiotic stimulus GO:0009628 341 0.013
single organism intracellular transport GO:1902582 207 0.012
appendage morphogenesis GO:0035107 397 0.012
protein maturation GO:0051604 71 0.012
negative regulation of nervous system development GO:0051961 92 0.012
purine nucleoside catabolic process GO:0006152 112 0.012
Human Mouse
regulation of cellular catabolic process GO:0031329 157 0.012
Human Mouse
chromatin silencing GO:0006342 76 0.012
regulation of cellular localization GO:0060341 136 0.012
cellular response to chemical stimulus GO:0070887 199 0.012
regulation of cellular amine metabolic process GO:0033238 3 0.012
positive regulation of macromolecule biosynthetic process GO:0010557 283 0.012
purine nucleotide metabolic process GO:0006163 146 0.012
Human Mouse
morphogenesis of an epithelium GO:0002009 276 0.012
adult locomotory behavior GO:0008344 76 0.012
tissue death GO:0016271 102 0.012
establishment of planar polarity GO:0001736 87 0.012
response to lipopolysaccharide GO:0032496 4 0.012
anterior posterior axis specification embryo GO:0008595 103 0.012
regulation of developmental growth GO:0048638 174 0.011
protein acylation GO:0043543 42 0.011
protein palmitoylation GO:0018345 2 0.011
learning or memory GO:0007611 141 0.011
organelle localization GO:0051640 148 0.011
immune response GO:0006955 246 0.011
transcription from rna polymerase ii promoter GO:0006366 368 0.011
cellular response to lipopolysaccharide GO:0071222 3 0.011
cellular protein localization GO:0034613 160 0.011
carbohydrate derivative metabolic process GO:1901135 217 0.011
Human Mouse
eye development GO:0001654 323 0.011
regulation of ion transport GO:0043269 39 0.011
posttranscriptional regulation of gene expression GO:0010608 145 0.011
g protein coupled receptor signaling pathway GO:0007186 136 0.011
negative regulation of programmed cell death GO:0043069 72 0.011
telencephalon development GO:0021537 2 0.011
imaginal disc derived appendage morphogenesis GO:0035114 395 0.011
regulation of growth GO:0040008 233 0.011
purine containing compound metabolic process GO:0072521 155 0.011
Human Mouse
positive regulation of nucleobase containing compound metabolic process GO:0045935 332 0.011
Human Mouse
negative regulation of epithelial cell proliferation GO:0050680 4 0.011
embryonic development via the syncytial blastoderm GO:0001700 148 0.011
negative regulation of transcription from rna polymerase ii promoter GO:0000122 119 0.011
regulation of catalytic activity GO:0050790 185 0.011
Human Mouse
regulation of microtubule based process GO:0032886 49 0.011
cellular ion homeostasis GO:0006873 39 0.011
nucleoside catabolic process GO:0009164 112 0.011
Human Mouse
regulation of anatomical structure morphogenesis GO:0022603 242 0.010
retina development in camera type eye GO:0060041 4 0.010
purine ribonucleotide metabolic process GO:0009150 145 0.010
Human Mouse
negative regulation of cellular protein metabolic process GO:0032269 85 0.010
positive regulation of mapk cascade GO:0043410 63 0.010
hindbrain development GO:0030902 2 0.010

Rlip disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

Disease DO term ID Size Probability Func Analog Org
disease of metabolism DOID:0014667 0 0.024
disease of anatomical entity DOID:7 0 0.012
nervous system disease DOID:863 0 0.012
disease of cellular proliferation DOID:14566 0 0.012
cancer DOID:162 0 0.012