Drosophila melanogaster

6 known processes

DnaJ-1 (Dmel_CG10578)

DnaJ-like-1

(Aliases: Dmel\CG10578,dhdj1,droj1,dHDJ1/HSP40,dhdJ1,dhdj-1,DroJ1,Hdj1,dHdj1,HSP40,HSP40/HDJ1,DnaJ1 64EF,EU3500,Hsp-40,CG10578,dHDJ1,anon-WO0140519.166,DNAJ-1,DNAJ1,DROJ1,Hsp40,anon-WO0172774.135)

DnaJ-1 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
transcription from rna polymerase ii promoter GO:0006366 368 0.460
Mouse
heat shock mediated polytene chromosome puffing GO:0035080 7 0.315
positive regulation of response to stimulus GO:0048584 323 0.247
signal transduction by phosphorylation GO:0023014 107 0.197
determination of adult lifespan GO:0008340 137 0.184
response to abiotic stimulus GO:0009628 341 0.168
mapk cascade GO:0000165 107 0.137
positive regulation of signaling GO:0023056 243 0.125
positive regulation of cell communication GO:0010647 250 0.124
germarium derived oocyte differentiation GO:0030706 29 0.115
intracellular signal transduction GO:0035556 300 0.097
erk1 and erk2 cascade GO:0070371 39 0.096
regulation of transcription from rna polymerase ii promoter GO:0006357 378 0.096
Mouse
small gtpase mediated signal transduction GO:0007264 88 0.093
ras protein signal transduction GO:0007265 88 0.091
multicellular organismal aging GO:0010259 140 0.088
regulation of mapk cascade GO:0043408 92 0.087
cellular response to heat GO:0034605 24 0.083
phosphorylation GO:0016310 294 0.082
positive regulation of phosphate metabolic process GO:0045937 139 0.078
Human
positive regulation of intracellular signal transduction GO:1902533 116 0.076
regulation of intracellular signal transduction GO:1902531 236 0.075
positive regulation of signal transduction GO:0009967 223 0.069
taxis GO:0042330 304 0.068
positive regulation of nucleobase containing compound metabolic process GO:0045935 332 0.067
Human
appendage morphogenesis GO:0035107 397 0.066
dna damage checkpoint GO:0000077 78 0.066
histolysis GO:0007559 102 0.063
positive regulation of nitrogen compound metabolic process GO:0051173 354 0.061
Human
regulation of multicellular organismal development GO:2000026 414 0.061
regulation of phosphorus metabolic process GO:0051174 210 0.060
Human
programmed cell death GO:0012501 257 0.060
aging GO:0007568 143 0.058
regulation of small gtpase mediated signal transduction GO:0051056 93 0.058
cellular protein modification process GO:0006464 438 0.052
g2 dna damage checkpoint GO:0031572 69 0.051
positive regulation of phosphorus metabolic process GO:0010562 139 0.050
Human
response to organic substance GO:0010033 284 0.048
Human Yeast
regulation of mitotic cell cycle phase transition GO:1901990 130 0.048
cellular response to chemical stimulus GO:0070887 199 0.048
Yeast
dna integrity checkpoint GO:0031570 81 0.046
regulation of gene expression epigenetic GO:0040029 128 0.046
regulation of phosphate metabolic process GO:0019220 210 0.046
Human
response to oxygen containing compound GO:1901700 200 0.046
gene silencing GO:0016458 138 0.045
developmental programmed cell death GO:0010623 138 0.045
positive regulation of transcription from rna polymerase ii promoter GO:0045944 204 0.043
regulation of molecular function GO:0065009 217 0.042
Human
regulation of phosphorylation GO:0042325 147 0.042
salivary gland histolysis GO:0035070 88 0.042
regulation of mitotic cell cycle GO:0007346 190 0.039
positive regulation of cellular biosynthetic process GO:0031328 316 0.038
mitotic g2 dna damage checkpoint GO:0007095 69 0.038
chemotaxis GO:0006935 249 0.037
positive regulation of transcription dna templated GO:0045893 266 0.037
tissue death GO:0016271 102 0.037
rna polymerase ii transcriptional preinitiation complex assembly GO:0051123 20 0.036
dna templated transcription initiation GO:0006352 25 0.036
germarium derived egg chamber formation GO:0007293 101 0.035
mitotic cell cycle checkpoint GO:0007093 88 0.035
response to starvation GO:0042594 97 0.035
response to temperature stimulus GO:0009266 106 0.035
positive regulation of ras protein signal transduction GO:0046579 43 0.034
neurological system process GO:0050877 358 0.034
positive regulation of phosphorylation GO:0042327 87 0.033
mitotic cell cycle phase transition GO:0044772 138 0.033
synaptic transmission GO:0007268 288 0.033
cell cycle phase transition GO:0044770 140 0.032
defense response to other organism GO:0098542 225 0.032
salivary gland development GO:0007431 162 0.032
protein modification process GO:0036211 438 0.031
gland morphogenesis GO:0022612 145 0.031
dendrite morphogenesis GO:0048813 199 0.030
regulation of ras protein signal transduction GO:0046578 93 0.030
mitotic dna damage checkpoint GO:0044773 74 0.030
regulation of localization GO:0032879 275 0.030
cellular response to dna damage stimulus GO:0006974 223 0.029
gland development GO:0048732 191 0.029
exocrine system development GO:0035272 162 0.028
intracellular transport GO:0046907 228 0.028
Yeast
negative regulation of rna metabolic process GO:0051253 251 0.027
Mouse
negative regulation of transcription from rna polymerase ii promoter GO:0000122 119 0.027
Mouse
polytene chromosome puffing GO:0035079 7 0.027
carbohydrate derivative catabolic process GO:1901136 118 0.027
Human
camera type eye development GO:0043010 4 0.027
regulation of nervous system development GO:0051960 248 0.026
negative regulation of cell cycle GO:0045786 116 0.026
appendage development GO:0048736 401 0.025
imaginal disc derived appendage morphogenesis GO:0035114 395 0.025
positive regulation of nucleic acid templated transcription GO:1903508 266 0.025
heterocycle catabolic process GO:0046700 166 0.025
Human
positive regulation of erk1 and erk2 cascade GO:0070374 36 0.025
nucleobase containing compound catabolic process GO:0034655 165 0.024
Human
organic cyclic compound catabolic process GO:1901361 168 0.024
Human
salivary gland cell autophagic cell death GO:0035071 83 0.024
mesenchymal cell differentiation GO:0048762 1 0.024
mating GO:0007618 120 0.024
nucleoside triphosphate metabolic process GO:0009141 120 0.024
Human
negative regulation of cell cycle phase transition GO:1901988 103 0.023
regulation of cellular ketone metabolic process GO:0010565 3 0.023
negative regulation of cell cycle process GO:0010948 109 0.023
dendrite development GO:0016358 204 0.023
embryonic pattern specification GO:0009880 174 0.022
organophosphate catabolic process GO:0046434 112 0.022
Human
macromolecular complex assembly GO:0065003 256 0.022
cell death GO:0008219 279 0.022
positive regulation of biosynthetic process GO:0009891 316 0.022
mitotic g2 m transition checkpoint GO:0044818 70 0.022
regulation of cell cycle phase transition GO:1901987 130 0.021
defense response GO:0006952 300 0.021
cellular amine metabolic process GO:0044106 12 0.021
negative regulation of transcription dna templated GO:0045892 237 0.021
Mouse
regulation of catalytic activity GO:0050790 185 0.021
Human
axonogenesis GO:0007409 290 0.021
head development GO:0060322 135 0.021
purine nucleoside triphosphate metabolic process GO:0009144 119 0.020
Human
regulation of erk1 and erk2 cascade GO:0070372 39 0.020
protein dna complex subunit organization GO:0071824 86 0.020
ribonucleoside triphosphate catabolic process GO:0009203 108 0.020
Human
purine ribonucleotide metabolic process GO:0009150 145 0.020
Human
aromatic compound catabolic process GO:0019439 166 0.020
Human
negative regulation of mitotic cell cycle phase transition GO:1901991 103 0.020
response to extracellular stimulus GO:0009991 116 0.020
response to oxygen levels GO:0070482 59 0.020
response to decreased oxygen levels GO:0036293 58 0.020
endocytosis GO:0006897 310 0.020
mitotic dna integrity checkpoint GO:0044774 75 0.020
cellular macromolecular complex assembly GO:0034622 153 0.020
positive regulation of macromolecule biosynthetic process GO:0010557 283 0.019
gravitaxis GO:0042332 26 0.019
cellularization GO:0007349 90 0.019
sensory organ morphogenesis GO:0090596 260 0.019
dna methylation GO:0006306 4 0.019
positive regulation of multicellular organismal process GO:0051240 143 0.019
response to ethanol GO:0045471 59 0.019
response to nutrient levels GO:0031667 114 0.019
body morphogenesis GO:0010171 2 0.019
macromolecular complex disassembly GO:0032984 37 0.019
oocyte differentiation GO:0009994 145 0.019
regulation of transport GO:0051049 181 0.019
autophagic cell death GO:0048102 83 0.019
vesicle mediated transport GO:0016192 381 0.018
negative regulation of cell communication GO:0010648 223 0.018
chromosome organization GO:0051276 360 0.018
regulation of cell death GO:0010941 173 0.018
negative regulation of cellular macromolecule biosynthetic process GO:2000113 267 0.018
Mouse
peptidyl lysine modification GO:0018205 57 0.018
response to endogenous stimulus GO:0009719 119 0.018
death GO:0016265 284 0.018
connective tissue development GO:0061448 3 0.018
cell cycle checkpoint GO:0000075 95 0.018
purine nucleotide metabolic process GO:0006163 146 0.017
Human
regulation of cell development GO:0060284 215 0.017
multicellular organismal reproductive behavior GO:0033057 110 0.017
photoreceptor cell differentiation GO:0046530 170 0.017
ribonucleoside triphosphate metabolic process GO:0009199 119 0.017
Human
purine ribonucleoside triphosphate catabolic process GO:0009207 108 0.017
Human
post embryonic appendage morphogenesis GO:0035120 385 0.017
muscle organ development GO:0007517 127 0.017
positive regulation of mapk cascade GO:0043410 63 0.017
response to organic cyclic compound GO:0014070 89 0.017
response to nitrogen compound GO:1901698 90 0.017
axon guidance GO:0007411 233 0.017
apoptotic process GO:0006915 159 0.016
response to biotic stimulus GO:0009607 294 0.016
ribose phosphate metabolic process GO:0019693 145 0.016
Human
homeostatic process GO:0042592 199 0.016
cellular response to radiation GO:0071478 52 0.016
ribonucleotide metabolic process GO:0009259 145 0.016
Human
response to lipopolysaccharide GO:0032496 4 0.016
negative regulation of nucleic acid templated transcription GO:1903507 240 0.016
Mouse
positive regulation of rna biosynthetic process GO:1902680 266 0.016
negative regulation of biosynthetic process GO:0009890 277 0.016
Mouse
regulation of protein localization GO:0032880 76 0.015
regulation of synapse assembly GO:0051963 94 0.015
multi multicellular organism process GO:0044706 123 0.015
forebrain development GO:0030900 2 0.015
negative regulation of gene expression epigenetic GO:0045814 77 0.015
phagocytosis GO:0006909 215 0.015
response to hypoxia GO:0001666 53 0.015
negative regulation of cellular protein metabolic process GO:0032269 85 0.015
negative regulation of mitotic cell cycle GO:0045930 109 0.014
purine ribonucleotide catabolic process GO:0009154 109 0.014
Human
negative regulation of reactive oxygen species metabolic process GO:2000378 1 0.014
cellular homeostasis GO:0019725 80 0.014
brain development GO:0007420 120 0.014
regulation of cell differentiation GO:0045595 302 0.014
protein complex disassembly GO:0043241 36 0.014
ribonucleoside catabolic process GO:0042454 112 0.014
Human
transcription initiation from rna polymerase ii promoter GO:0006367 25 0.014
peptidyl amino acid modification GO:0018193 105 0.014
positive regulation of synapse assembly GO:0051965 29 0.014
nucleoside catabolic process GO:0009164 112 0.014
Human
response to alcohol GO:0097305 95 0.014
nucleoside triphosphate catabolic process GO:0009143 108 0.014
Human
chromatin silencing GO:0006342 76 0.013
amine metabolic process GO:0009308 12 0.013
compound eye morphogenesis GO:0001745 249 0.013
cytoskeleton dependent intracellular transport GO:0030705 44 0.013
protein localization GO:0008104 284 0.013
Yeast
regulation of cellular amine metabolic process GO:0033238 3 0.013
cellular protein complex disassembly GO:0043624 35 0.013
regulation of neurogenesis GO:0050767 158 0.013
pigmentation GO:0043473 75 0.013
positive regulation of hydrolase activity GO:0051345 78 0.013
Human
single organism catabolic process GO:0044712 228 0.013
Human Yeast
positive regulation of macromolecule metabolic process GO:0010604 405 0.013
spindle assembly GO:0051225 80 0.013
modification dependent macromolecule catabolic process GO:0043632 79 0.013
Yeast
cellular nitrogen compound catabolic process GO:0044270 165 0.013
Human
negative regulation of rna biosynthetic process GO:1902679 240 0.013
Mouse
positive regulation of cell motility GO:2000147 3 0.013
negative regulation of intracellular signal transduction GO:1902532 57 0.012
muscle structure development GO:0061061 224 0.012
catabolic process GO:0009056 409 0.012
Human Yeast
purine containing compound metabolic process GO:0072521 155 0.012
Human
imaginal disc pattern formation GO:0007447 91 0.012
glycosyl compound catabolic process GO:1901658 112 0.012
Human
response to other organism GO:0051707 293 0.012
spermatogenesis GO:0007283 200 0.012
purine nucleoside triphosphate catabolic process GO:0009146 108 0.012
Human
enzyme linked receptor protein signaling pathway GO:0007167 179 0.012
cellular ketone metabolic process GO:0042180 24 0.012
positive regulation of molecular function GO:0044093 136 0.012
Human
negative regulation of signaling GO:0023057 219 0.012
positive regulation of gene expression GO:0010628 290 0.012
regulation of tube size open tracheal system GO:0035151 43 0.012
circulatory system development GO:0072359 82 0.012
imaginal disc derived appendage development GO:0048737 399 0.012
ubiquitin homeostasis GO:0010992 1 0.012
axon development GO:0061564 297 0.012
retina development in camera type eye GO:0060041 4 0.012
positive regulation of small gtpase mediated signal transduction GO:0051057 43 0.012
neuron projection guidance GO:0097485 241 0.012
organic substance transport GO:0071702 257 0.012
Yeast
negative regulation of response to stimulus GO:0048585 258 0.012
embryonic morphogenesis GO:0048598 206 0.012
regulation of apoptotic process GO:0042981 130 0.011
intracellular protein transmembrane import GO:0044743 4 0.011
multi organism reproductive behavior GO:0044705 121 0.011
glycosyl compound metabolic process GO:1901657 127 0.011
Human
response to external biotic stimulus GO:0043207 293 0.011
actin filament organization GO:0007015 126 0.011
negative regulation of cellular metabolic process GO:0031324 382 0.011
Mouse
regulation of intracellular transport GO:0032386 64 0.011
mesenchymal cell development GO:0014031 1 0.011
single organism behavior GO:0044708 391 0.011
regulation of cellular response to stress GO:0080135 89 0.011
positive regulation of purine nucleotide metabolic process GO:1900544 55 0.011
Human
cellular response to organic substance GO:0071310 132 0.011
Yeast
regulation of neuron differentiation GO:0045664 103 0.011
protein ubiquitination GO:0016567 70 0.011
regulation of cellular amino acid metabolic process GO:0006521 0 0.011
regulation of catabolic process GO:0009894 170 0.011
Human
nucleoside phosphate catabolic process GO:1901292 110 0.011
Human
organelle assembly GO:0070925 198 0.011
regulation of cell cycle GO:0051726 291 0.011
negative regulation of erk1 and erk2 cascade GO:0070373 3 0.011
endomembrane system organization GO:0010256 119 0.011
biological adhesion GO:0022610 138 0.011
retrograde transport endosome to golgi GO:0042147 3 0.011
regulation of notch signaling pathway GO:0008593 100 0.011
response to organonitrogen compound GO:0010243 75 0.011
camera type eye morphogenesis GO:0048593 2 0.011
negative regulation of phosphorylation GO:0042326 35 0.011
limb development GO:0060173 1 0.011
purine ribonucleoside triphosphate metabolic process GO:0009205 119 0.011
Human
positive regulation of apoptotic signaling pathway GO:2001235 4 0.011
negative regulation of mapk cascade GO:0043409 23 0.011
negative regulation of growth GO:0045926 84 0.011
dna templated transcriptional preinitiation complex assembly GO:0070897 20 0.011
protein transport GO:0015031 155 0.011
Yeast
positive regulation of purine nucleotide catabolic process GO:0033123 46 0.010
Human
apoptotic process involved in morphogenesis GO:0060561 3 0.010
columnar cuboidal epithelial cell differentiation GO:0002065 256 0.010
regulation of synapse organization GO:0050807 110 0.010
purine ribonucleoside metabolic process GO:0046128 127 0.010
Human
atp catabolic process GO:0006200 38 0.010
Human
compound eye development GO:0048749 307 0.010
extrinsic apoptotic signaling pathway GO:0097191 1 0.010
multi organism behavior GO:0051705 175 0.010
acetylcholine metabolic process GO:0008291 2 0.010
developmental pigmentation GO:0048066 68 0.010
chromatin remodeling GO:0006338 72 0.010
positive regulation of rna metabolic process GO:0051254 271 0.010
small molecule metabolic process GO:0044281 305 0.010
Human

DnaJ-1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.024
cardiovascular system disease DOID:1287 0 0.015
musculoskeletal system disease DOID:17 0 0.012
sensory system disease DOID:0050155 0 0.011
eye and adnexa disease DOID:1492 0 0.011
nervous system disease DOID:863 0 0.011
disease of metabolism DOID:0014667 0 0.011
inherited metabolic disorder DOID:655 0 0.011