Drosophila melanogaster

103 known processes

crc (Dmel_CG8669)

cryptocephal

(Aliases: dATF-4,CG8669,929,ATF4/crc,l(2)crc,Dmel\CG8669,ATF-4)

crc biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
single organism behavior GO:0044708 391 0.671
positive regulation of transcription from rna polymerase ii promoter GO:0045944 204 0.605
chitin based cuticle sclerotization GO:0007593 19 0.469
positive regulation of rna metabolic process GO:0051254 271 0.458
response to ethanol GO:0045471 59 0.359
sleep GO:0030431 49 0.334
adult behavior GO:0030534 137 0.314
circadian sleep wake cycle GO:0042745 28 0.294
positive regulation of gene expression GO:0010628 290 0.281
response to oxygen containing compound GO:1901700 200 0.271
sensory perception of chemical stimulus GO:0007606 116 0.258
nuclear import GO:0051170 51 0.243
nuclear transport GO:0051169 72 0.214
ion transmembrane transport GO:0034220 122 0.211
regulation of chitin based cuticle tanning GO:0007564 14 0.204
response to alcohol GO:0097305 95 0.172
dopamine biosynthetic process GO:0042416 3 0.154
positive regulation of rna biosynthetic process GO:1902680 266 0.150
cellular response to chemical stimulus GO:0070887 199 0.150
chemosensory behavior GO:0007635 106 0.147
multi organism behavior GO:0051705 175 0.133
wing disc morphogenesis GO:0007472 344 0.132
cuticle pigmentation GO:0048067 22 0.131
imaginal disc derived appendage morphogenesis GO:0035114 395 0.115
regulation of cuticle pigmentation GO:0048079 16 0.105
response to organic substance GO:0010033 284 0.104
positive regulation of macromolecule biosynthetic process GO:0010557 283 0.101
cellular response to abiotic stimulus GO:0071214 58 0.100
negative regulation of nitrogen compound metabolic process GO:0051172 265 0.097
multi multicellular organism process GO:0044706 123 0.095
sensory perception of smell GO:0007608 80 0.089
molting cycle process GO:0022404 29 0.087
appendage morphogenesis GO:0035107 397 0.086
protein targeting to nucleus GO:0044744 51 0.084
negative regulation of transcription from rna polymerase ii promoter GO:0000122 119 0.083
positive regulation of transcription dna templated GO:0045893 266 0.081
regulation of adult chitin containing cuticle pigmentation GO:0048082 13 0.078
cellular response to dna damage stimulus GO:0006974 223 0.075
courtship behavior GO:0007619 68 0.073
male mating behavior GO:0060179 70 0.072
appendage development GO:0048736 401 0.071
phagocytosis GO:0006909 215 0.067
protein localization to nucleus GO:0034504 55 0.067
cellular catabolic process GO:0044248 372 0.062
molting cycle chitin based cuticle GO:0007591 56 0.057
cellular response to ionizing radiation GO:0071479 15 0.051
regulation of transcription from rna polymerase ii promoter GO:0006357 378 0.049
cellular response to oxygen containing compound GO:1901701 79 0.047
response to abiotic stimulus GO:0009628 341 0.047
positive regulation of cellular biosynthetic process GO:0031328 316 0.047
positive regulation of protein localization to nucleus GO:1900182 21 0.046
developmental growth GO:0048589 280 0.045
adult chitin containing cuticle pigmentation GO:0048085 16 0.045
response to nitrogen compound GO:1901698 90 0.045
sensory perception GO:0007600 196 0.043
negative regulation of cell death GO:0060548 81 0.043
single organism nuclear import GO:1902593 51 0.043
catechol containing compound biosynthetic process GO:0009713 3 0.041
catecholamine biosynthetic process GO:0042423 3 0.041
lipid metabolic process GO:0006629 121 0.041
response to insecticide GO:0017085 14 0.040
connective tissue development GO:0061448 3 0.039
response to endogenous stimulus GO:0009719 119 0.039
neuron fate commitment GO:0048663 50 0.038
protein targeting GO:0006605 64 0.038
regulation of epithelial cell proliferation GO:0050678 4 0.037
ion transport GO:0006811 145 0.037
negative regulation of transcription dna templated GO:0045892 237 0.036
imaginal disc derived wing morphogenesis GO:0007476 337 0.036
regulation of phosphatase activity GO:0010921 3 0.036
positive regulation of macromolecule metabolic process GO:0010604 405 0.036
molting cycle GO:0042303 56 0.036
pupal development GO:0035209 11 0.035
rhythmic behavior GO:0007622 76 0.034
circadian behavior GO:0048512 76 0.034
negative regulation of cellular metabolic process GO:0031324 382 0.034
serotonin metabolic process GO:0042428 2 0.033
homeostatic process GO:0042592 199 0.033
positive regulation of nucleic acid templated transcription GO:1903508 266 0.033
adult locomotory behavior GO:0008344 76 0.033
circadian sleep wake cycle sleep GO:0050802 23 0.033
transmembrane transport GO:0055085 139 0.033
protein import GO:0017038 55 0.033
positive regulation of cell death GO:0010942 69 0.032
positive regulation of multicellular organismal process GO:0051240 143 0.031
regulation of cytoplasmic transport GO:1903649 47 0.031
vitamin biosynthetic process GO:0009110 1 0.030
post embryonic appendage morphogenesis GO:0035120 385 0.030
regulation of molecular function GO:0065009 217 0.030
aging GO:0007568 143 0.029
axon development GO:0061564 297 0.029
carboxylic acid metabolic process GO:0019752 92 0.029
nucleocytoplasmic transport GO:0006913 72 0.028
regulation of cellular amide metabolic process GO:0034248 39 0.028
negative regulation of biosynthetic process GO:0009890 277 0.028
protein import into nucleus GO:0006606 51 0.027
response to alkaloid GO:0043279 26 0.025
catabolic process GO:0009056 409 0.025
regulation of transport GO:0051049 181 0.024
cell cycle phase transition GO:0044770 140 0.024
macromolecule catabolic process GO:0009057 161 0.024
single organism intracellular transport GO:1902582 207 0.024
regulation of hemocyte proliferation GO:0035206 37 0.023
tyrosine metabolic process GO:0006570 1 0.023
aggressive behavior GO:0002118 63 0.022
negative regulation of rna metabolic process GO:0051253 251 0.022
regulation of protein metabolic process GO:0051246 256 0.022
positive regulation of programmed cell death GO:0043068 62 0.022
regulation of response to dna damage stimulus GO:2001020 23 0.022
intracellular protein transport GO:0006886 104 0.022
intracellular transport GO:0046907 228 0.021
primary amino compound metabolic process GO:1901160 2 0.021
multi organism reproductive behavior GO:0044705 121 0.021
cuticle development GO:0042335 86 0.021
positive regulation of signal transduction GO:0009967 223 0.020
positive regulation of nucleobase containing compound metabolic process GO:0045935 332 0.020
regulation of cellular localization GO:0060341 136 0.020
negative regulation of signal transduction GO:0009968 206 0.020
single organism biosynthetic process GO:0044711 206 0.020
response to starvation GO:0042594 97 0.019
regulation of multicellular organismal development GO:2000026 414 0.019
regulation of protein import into nucleus GO:0042306 28 0.019
apoptotic process GO:0006915 159 0.019
imaginal disc derived leg morphogenesis GO:0007480 80 0.019
regulation of cell death GO:0010941 173 0.019
endocytosis GO:0006897 310 0.019
protein transport GO:0015031 155 0.019
regulation of cell cycle phase transition GO:1901987 130 0.019
transcription from rna polymerase ii promoter GO:0006366 368 0.018
primary amino compound biosynthetic process GO:1901162 2 0.018
mitotic cell cycle phase transition GO:0044772 138 0.018
cell aging GO:0007569 2 0.018
organic substance transport GO:0071702 257 0.018
negative regulation of cellular biosynthetic process GO:0031327 277 0.017
regulation of circadian sleep wake cycle GO:0042749 25 0.017
vesicle mediated transport GO:0016192 381 0.017
g2 m transition of mitotic cell cycle GO:0000086 19 0.017
regulation of immune response GO:0050776 118 0.017
positive regulation of transcription factor import into nucleus GO:0042993 19 0.017
cytoplasmic transport GO:0016482 130 0.017
regulation of nucleocytoplasmic transport GO:0046822 35 0.017
response to extracellular stimulus GO:0009991 116 0.017
negative regulation of nucleic acid templated transcription GO:1903507 240 0.016
response to organonitrogen compound GO:0010243 75 0.016
response to anesthetic GO:0072347 9 0.016
central nervous system development GO:0007417 201 0.016
mesenchymal cell differentiation GO:0048762 1 0.016
response to organic cyclic compound GO:0014070 89 0.015
regulation of programmed cell death GO:0043067 152 0.015
positive regulation of molecular function GO:0044093 136 0.015
organic acid metabolic process GO:0006082 103 0.015
amine metabolic process GO:0009308 12 0.015
response to light stimulus GO:0009416 124 0.015
developmental maturation GO:0021700 172 0.014
pigmentation GO:0043473 75 0.014
reproductive behavior GO:0019098 122 0.014
cellular nitrogen compound catabolic process GO:0044270 165 0.014
meiotic nuclear division GO:0007126 151 0.014
organic substance catabolic process GO:1901575 308 0.014
response to superoxide GO:0000303 3 0.014
regulation of intracellular protein transport GO:0033157 46 0.014
negative regulation of signaling GO:0023057 219 0.014
regulation of protein localization GO:0032880 76 0.014
leg disc development GO:0035218 92 0.013
head development GO:0060322 135 0.013
leg disc morphogenesis GO:0007478 80 0.013
dorsal ventral pattern formation GO:0009953 133 0.013
small molecule metabolic process GO:0044281 305 0.013
positive regulation of developmental growth GO:0048639 62 0.013
positive regulation of cell differentiation GO:0045597 64 0.013
chitin based cuticle development GO:0040003 49 0.013
fat soluble vitamin biosynthetic process GO:0042362 1 0.012
cellular response to radiation GO:0071478 52 0.012
embryonic development via the syncytial blastoderm GO:0001700 148 0.012
cellular ketone metabolic process GO:0042180 24 0.012
imaginal disc derived appendage development GO:0048737 399 0.012
limb development GO:0060173 1 0.012
aromatic amino acid family metabolic process GO:0009072 3 0.012
regulation of cellular response to stress GO:0080135 89 0.012
regulation of hormone levels GO:0010817 40 0.012
embryo development ending in birth or egg hatching GO:0009792 152 0.012
positive regulation of epithelial cell differentiation GO:0030858 1 0.012
response to oxygen radical GO:0000305 3 0.012
cellular response to oxidative stress GO:0034599 28 0.012
mesenchymal cell development GO:0014031 1 0.011
oxoacid metabolic process GO:0043436 103 0.011
regulation of cell cycle GO:0051726 291 0.011
body morphogenesis GO:0010171 2 0.011
response to radiation GO:0009314 155 0.011
sex differentiation GO:0007548 81 0.011
multicellular organismal reproductive behavior GO:0033057 110 0.011
cellular amino acid metabolic process GO:0006520 61 0.010
muscle structure development GO:0061061 224 0.010
cellular macromolecule localization GO:0070727 220 0.010

crc disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.028
disease of cellular proliferation DOID:14566 0 0.020