Drosophila melanogaster

239 known processes

Pka-C1 (Dmel_CG4379)

cAMP-dependent protein kinase 1

(Aliases: CdkA,l(2)s4402,C,Dmel\CG4379,pka,Dcpk,CG4379,DCO,pKA,PKA-C1,pka C1,PKA,Cos1,dPKA,l(2)01272,Cos-1,pkA,dco,Cos,Dco,l(2)cos[[1]],pka-C1,PkaC1,PKAC1,PKA Cl,cos1,PKAcA,DC0,dcO,6353,pka-c1,Pka-C,Pka,PKA CI,PKAc,Dc0)

Pka-C1 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
cognition GO:0050890 141 0.992
neurological system process GO:0050877 358 0.989
oocyte differentiation GO:0009994 145 0.984
learning or memory GO:0007611 141 0.977
cell motility GO:0048870 251 0.974
single organism behavior GO:0044708 391 0.970
negative regulation of cellular biosynthetic process GO:0031327 277 0.967
oocyte development GO:0048599 124 0.955
single organism cellular localization GO:1902580 180 0.953
regulation of transcription from rna polymerase ii promoter GO:0006357 378 0.938
long term memory GO:0007616 62 0.930
negative regulation of nitrogen compound metabolic process GO:0051172 265 0.927
positive regulation of rna metabolic process GO:0051254 271 0.901
transcription from rna polymerase ii promoter GO:0006366 368 0.880
memory GO:0007613 94 0.876
learning GO:0007612 75 0.873
negative regulation of rna metabolic process GO:0051253 251 0.870
positive regulation of biosynthetic process GO:0009891 316 0.859
negative regulation of signaling GO:0023057 219 0.850
negative regulation of cellular metabolic process GO:0031324 382 0.846
negative regulation of biosynthetic process GO:0009890 277 0.838
circadian rhythm GO:0007623 105 0.825
imaginal disc derived appendage morphogenesis GO:0035114 395 0.807
cell migration GO:0016477 238 0.794
death GO:0016265 284 0.787
signal release GO:0023061 49 0.776
negative regulation of gene expression GO:0010629 387 0.766
response to organic substance GO:0010033 284 0.753
Human Mouse Rat
wing disc morphogenesis GO:0007472 344 0.748
negative regulation of cell cycle GO:0045786 116 0.748
Mouse Rat
positive regulation of nitrogen compound metabolic process GO:0051173 354 0.730
positive regulation of cellular biosynthetic process GO:0031328 316 0.727
regulation of cell cycle GO:0051726 291 0.725
Mouse Rat
positive regulation of nucleic acid templated transcription GO:1903508 266 0.724
imaginal disc derived appendage development GO:0048737 399 0.722
negative regulation of macromolecule biosynthetic process GO:0010558 270 0.706
oocyte microtubule cytoskeleton organization GO:0016325 35 0.701
cellular protein modification process GO:0006464 438 0.700
positive regulation of macromolecule biosynthetic process GO:0010557 283 0.699
morphogenesis of an epithelium GO:0002009 276 0.693
Mouse
positive regulation of gene expression GO:0010628 290 0.684
regulation of transport GO:0051049 181 0.675
Mouse
regulation of localization GO:0032879 275 0.653
negative regulation of transcription from rna polymerase ii promoter GO:0000122 119 0.647
regulation of multicellular organismal development GO:2000026 414 0.641
actin filament based process GO:0030029 220 0.638
positive regulation of transcription dna templated GO:0045893 266 0.637
small molecule metabolic process GO:0044281 305 0.636
single organism intracellular transport GO:1902582 207 0.634
Mouse
pole plasm oskar mrna localization GO:0045451 46 0.633
regulation of epithelial cell proliferation GO:0050678 4 0.633
growth GO:0040007 359 0.626
Yeast
regionalization GO:0003002 416 0.624
response to abiotic stimulus GO:0009628 341 0.621
negative regulation of cellular macromolecule biosynthetic process GO:2000113 267 0.619
circadian behavior GO:0048512 76 0.612
localization of cell GO:0051674 257 0.602
tissue migration GO:0090130 155 0.591
establishment of localization in cell GO:0051649 402 0.581
Mouse
tissue morphogenesis GO:0048729 297 0.575
Mouse
negative regulation of nucleic acid templated transcription GO:1903507 240 0.575
cellular macromolecule localization GO:0070727 220 0.572
negative regulation of transcription dna templated GO:0045892 237 0.571
response to temperature stimulus GO:0009266 106 0.568
positive regulation of rna biosynthetic process GO:1902680 266 0.563
negative regulation of cell communication GO:0010648 223 0.562
positive regulation of macromolecule metabolic process GO:0010604 405 0.561
developmental maturation GO:0021700 172 0.558
regulation of cellular localization GO:0060341 136 0.552
negative regulation of rna biosynthetic process GO:1902679 240 0.549
histone modification GO:0016570 106 0.546
protein phosphorylation GO:0006468 169 0.529
negative regulation of response to stimulus GO:0048585 258 0.518
negative regulation of intracellular signal transduction GO:1902532 57 0.513
response to oxygen containing compound GO:1901700 200 0.500
Human
olfactory learning GO:0008355 56 0.496
ameboidal type cell migration GO:0001667 151 0.485
regulation of phosphorus metabolic process GO:0051174 210 0.480
regulation of protein metabolic process GO:0051246 256 0.480
Human Mouse
phosphorylation GO:0016310 294 0.473
oxoacid metabolic process GO:0043436 103 0.471
programmed cell death GO:0012501 257 0.470
protein targeting to nucleus GO:0044744 51 0.452
regulation of molecular function GO:0065009 217 0.448
epithelium migration GO:0090132 148 0.448
regulation of anatomical structure morphogenesis GO:0022603 242 0.438
regulation of cell cycle process GO:0010564 181 0.430
Mouse
nucleocytoplasmic transport GO:0006913 72 0.429
Mouse
developmental growth GO:0048589 280 0.423
circulatory system development GO:0072359 82 0.423
regulation of phosphate metabolic process GO:0019220 210 0.420
negative regulation of nucleobase containing compound metabolic process GO:0045934 261 0.418
spermatogenesis GO:0007283 200 0.410
Mouse
covalent chromatin modification GO:0016569 106 0.406
organic substance transport GO:0071702 257 0.403
Mouse
positive regulation of transcription from rna polymerase ii promoter GO:0045944 204 0.395
rna localization GO:0006403 115 0.392
germarium derived egg chamber formation GO:0007293 101 0.392
locomotor rhythm GO:0045475 56 0.391
regulation of wnt signaling pathway GO:0030111 68 0.388
smoothened signaling pathway GO:0007224 49 0.380
cell division GO:0051301 248 0.375
cellular amine metabolic process GO:0044106 12 0.370
regulation of cellular protein metabolic process GO:0032268 243 0.367
Human
appendage morphogenesis GO:0035107 397 0.356
organic acid metabolic process GO:0006082 103 0.353
sensory organ morphogenesis GO:0090596 260 0.351
organonitrogen compound metabolic process GO:1901564 318 0.346
regulation of mitotic cell cycle GO:0007346 190 0.345
cell fate determination GO:0001709 91 0.336
respiratory system development GO:0060541 213 0.333
protein modification process GO:0036211 438 0.331
oocyte axis specification GO:0007309 108 0.330
imaginal disc derived wing morphogenesis GO:0007476 337 0.329
striated muscle cell differentiation GO:0051146 90 0.328
appendage development GO:0048736 401 0.325
nitrogen compound transport GO:0071705 85 0.310
eye morphogenesis GO:0048592 260 0.309
nuclear transport GO:0051169 72 0.309
Mouse
chromatin modification GO:0016568 147 0.306
ion transport GO:0006811 145 0.301
regulation of organ morphogenesis GO:2000027 78 0.299
axis specification GO:0009798 167 0.296
protein localization to nucleus GO:0034504 55 0.295
developmental pigmentation GO:0048066 68 0.291
cellular response to chemical stimulus GO:0070887 199 0.288
Human Mouse
cell maturation GO:0048469 144 0.281
rhythmic behavior GO:0007622 76 0.281
regulation of cell proliferation GO:0042127 163 0.276
embryonic morphogenesis GO:0048598 206 0.272
Mouse
regulation of neurotransmitter levels GO:0001505 38 0.270
regulation of behavior GO:0050795 75 0.269
intracellular transport GO:0046907 228 0.264
Mouse
negative regulation of kinase activity GO:0033673 16 0.263
spermatid differentiation GO:0048515 114 0.258
Mouse
cellular response to abiotic stimulus GO:0071214 58 0.253
ribonucleotide metabolic process GO:0009259 145 0.253
vesicle mediated transport GO:0016192 381 0.252
positive regulation of cell communication GO:0010647 250 0.252
rhythmic process GO:0048511 106 0.250
positive regulation of signaling GO:0023056 243 0.250
anterior posterior pattern specification GO:0009952 136 0.247
oocyte construction GO:0007308 112 0.244
central nervous system development GO:0007417 201 0.244
establishment of tissue polarity GO:0007164 87 0.241
nuclear import GO:0051170 51 0.241
signal transduction by phosphorylation GO:0023014 107 0.239
heart development GO:0007507 82 0.238
chromatin organization GO:0006325 207 0.237
negative regulation of cell proliferation GO:0008285 69 0.234
eye photoreceptor cell fate commitment GO:0042706 37 0.229
response to radiation GO:0009314 155 0.228
actin cytoskeleton organization GO:0030036 206 0.226
photoreceptor cell fate commitment GO:0046552 41 0.223
regulation of phosphorylation GO:0042325 147 0.222
response to endogenous stimulus GO:0009719 119 0.219
Mouse Rat
anterior posterior axis specification GO:0009948 109 0.216
male gamete generation GO:0048232 201 0.213
Mouse
renal system development GO:0072001 72 0.212
regulation of epithelial cell differentiation GO:0030856 4 0.208
negative regulation of catalytic activity GO:0043086 42 0.203
r7 cell differentiation GO:0045466 43 0.200
chemical homeostasis GO:0048878 92 0.199
Human
pigmentation GO:0043473 75 0.199
compound eye morphogenesis GO:0001745 249 0.197
mapk cascade GO:0000165 107 0.195
regulation of cell death GO:0010941 173 0.194
positive regulation of cell migration GO:0030335 2 0.188
oocyte anterior posterior axis specification GO:0007314 72 0.188
epithelial cell migration GO:0010631 148 0.188
cellular protein localization GO:0034613 160 0.187
Mouse
compound eye development GO:0048749 307 0.187
regulation of apoptotic process GO:0042981 130 0.184
catabolic process GO:0009056 409 0.184
Human
peptidyl lysine modification GO:0018205 57 0.184
positive regulation of response to stimulus GO:0048584 323 0.182
compound eye photoreceptor fate commitment GO:0001752 36 0.182
cell death GO:0008219 279 0.180
negative regulation of phosphorylation GO:0042326 35 0.177
forebrain development GO:0030900 2 0.177
response to light stimulus GO:0009416 124 0.176
negative regulation of signal transduction GO:0009968 206 0.172
epithelial cell differentiation GO:0030855 322 0.171
organic substance catabolic process GO:1901575 308 0.169
Human
intracellular mrna localization involved in pattern specification process GO:0060810 56 0.169
enzyme linked receptor protein signaling pathway GO:0007167 179 0.169
epidermal cell differentiation GO:0009913 51 0.166
protein import into nucleus GO:0006606 51 0.166
regulation of secretion by cell GO:1903530 39 0.165
anterior posterior axis specification embryo GO:0008595 103 0.165
reproductive behavior GO:0019098 122 0.163
Worm
regulation of catabolic process GO:0009894 170 0.163
Human
macromolecular complex assembly GO:0065003 256 0.161
eye development GO:0001654 323 0.160
segmentation GO:0035282 207 0.157
regulation of kinase activity GO:0043549 53 0.157
associative learning GO:0008306 65 0.156
protein complex assembly GO:0006461 200 0.156
positive regulation of catabolic process GO:0009896 105 0.154
endocytosis GO:0006897 310 0.153
negative regulation of phosphorus metabolic process GO:0010563 45 0.147
positive regulation of nucleobase containing compound metabolic process GO:0045935 332 0.146
regulation of dendrite morphogenesis GO:0048814 28 0.143
protein import GO:0017038 55 0.142
canonical wnt signaling pathway GO:0060070 21 0.140
establishment of protein localization to organelle GO:0072594 62 0.140
positive regulation of transport GO:0051050 92 0.139
Mouse
regulation of photoreceptor cell differentiation GO:0046532 34 0.138
cellular catabolic process GO:0044248 372 0.136
Human
tube development GO:0035295 244 0.135
Mouse
carboxylic acid metabolic process GO:0019752 92 0.133
gland development GO:0048732 191 0.129
eye photoreceptor cell differentiation GO:0001754 145 0.129
compound eye photoreceptor cell differentiation GO:0001751 140 0.129
regulation of developmental pigmentation GO:0048070 24 0.127
connective tissue development GO:0061448 3 0.127
imaginal disc derived wing margin morphogenesis GO:0008587 41 0.127
cellular response to molecule of bacterial origin GO:0071219 3 0.126
protein localization to organelle GO:0033365 82 0.125
autophagic vacuole assembly GO:0000045 2 0.125
purine containing compound metabolic process GO:0072521 155 0.124
cellular chemical homeostasis GO:0055082 40 0.121
Human
regulation of cellular ketone metabolic process GO:0010565 3 0.121
positive regulation of multicellular organismal process GO:0051240 143 0.120
Worm
carbohydrate derivative metabolic process GO:1901135 217 0.120
regulation of smoothened signaling pathway GO:0008589 28 0.120
urogenital system development GO:0001655 72 0.118
protein localization GO:0008104 284 0.115
Mouse
cytoplasmic transport GO:0016482 130 0.115
Mouse
rna splicing GO:0008380 83 0.114
circulatory system process GO:0003013 37 0.113
heart morphogenesis GO:0003007 32 0.112
regulation of system process GO:0044057 36 0.112
heart process GO:0003015 37 0.111
single organism nuclear import GO:1902593 51 0.110
cell proliferation GO:0008283 299 0.107
fertilization GO:0009566 26 0.105
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 65 0.104
germarium derived oocyte fate determination GO:0007294 26 0.104
regulation of cellular component movement GO:0051270 42 0.103
homeostatic process GO:0042592 199 0.102
Human
ion transmembrane transport GO:0034220 122 0.101
regulation of growth GO:0040008 233 0.100
negative regulation of epithelial cell proliferation GO:0050680 4 0.098
regulation of protein localization GO:0032880 76 0.097
Mouse
chemotaxis GO:0006935 249 0.097
determination of adult lifespan GO:0008340 137 0.097
organelle fission GO:0048285 340 0.097
chromosome organization GO:0051276 360 0.096
regulation of mapk cascade GO:0043408 92 0.096
ovarian follicle cell stalk formation GO:0030713 17 0.095
head development GO:0060322 135 0.095
negative regulation of protein modification process GO:0031400 29 0.095
oocyte localization involved in germarium derived egg chamber formation GO:0030720 12 0.094
regulation of response to external stimulus GO:0032101 115 0.094
muscle structure development GO:0061061 224 0.094
morphogenesis of a polarized epithelium GO:0001738 93 0.093
ribose phosphate metabolic process GO:0019693 145 0.093
regulation of protein modification process GO:0031399 112 0.093
muscle cell differentiation GO:0042692 103 0.093
intracellular mrna localization involved in anterior posterior axis specification GO:0060811 53 0.093
dendrite morphogenesis GO:0048813 199 0.092
cellular response to dna damage stimulus GO:0006974 223 0.092
negative regulation of cell cycle process GO:0010948 109 0.091
nucleobase containing small molecule metabolic process GO:0055086 174 0.090
embryonic pattern specification GO:0009880 174 0.089
axon guidance GO:0007411 233 0.089
stem cell differentiation GO:0048863 117 0.089
response to insulin GO:0032868 29 0.088
axonogenesis GO:0007409 290 0.087
positive regulation of cell death GO:0010942 69 0.087
purine nucleoside metabolic process GO:0042278 127 0.087
protein maturation GO:0051604 71 0.087
Mouse
cellular response to organic substance GO:0071310 132 0.087
Human Mouse
regulation of catalytic activity GO:0050790 185 0.086
epithelial cell development GO:0002064 274 0.084
renal tubule morphogenesis GO:0061333 44 0.084
regulation of cell motility GO:2000145 23 0.083
axon development GO:0061564 297 0.083
regulation of organelle organization GO:0033043 196 0.082
muscle organ development GO:0007517 127 0.082
immune system process GO:0002376 347 0.082
regulation of protein phosphorylation GO:0001932 64 0.082
cellular response to external stimulus GO:0071496 66 0.082
body morphogenesis GO:0010171 2 0.082
maternal determination of anterior posterior axis embryo GO:0008358 74 0.080
regulation of protein catabolic process GO:0042176 55 0.079
Human
post embryonic appendage morphogenesis GO:0035120 385 0.079
apoptotic process GO:0006915 159 0.079
negative regulation of phosphate metabolic process GO:0045936 45 0.077
positive regulation of cellular catabolic process GO:0031331 95 0.076
cellular response to endogenous stimulus GO:0071495 80 0.076
Mouse
regulation of cell cycle phase transition GO:1901987 130 0.076
cellular response to light stimulus GO:0071482 37 0.076
secretion GO:0046903 109 0.075
multicellular organismal aging GO:0010259 140 0.074
photoreceptor cell fate specification GO:0043704 9 0.074
locomotory behavior GO:0007626 176 0.074
mating behavior GO:0007617 106 0.071
olfactory behavior GO:0042048 97 0.070
sensory perception GO:0007600 196 0.070
cell growth GO:0016049 108 0.070
secretion by cell GO:0032940 101 0.068
neuron projection guidance GO:0097485 241 0.068
organophosphate metabolic process GO:0019637 195 0.067
tripartite regional subdivision GO:0007351 103 0.067
regulation of r7 cell differentiation GO:0045676 15 0.067
embryonic axis specification GO:0000578 107 0.067
multi multicellular organism process GO:0044706 123 0.067
Worm
regulation of cell morphogenesis involved in differentiation GO:0010769 61 0.066
regulation of establishment of protein localization GO:0070201 61 0.066
Mouse
regulation of protein import into nucleus GO:0042306 28 0.066
blood circulation GO:0008015 26 0.066
regulation of nucleocytoplasmic transport GO:0046822 35 0.065
Mouse
internal protein amino acid acetylation GO:0006475 38 0.064
regulation of locomotion GO:0040012 42 0.064
amine metabolic process GO:0009308 12 0.064
positive regulation of molecular function GO:0044093 136 0.064
exocrine system development GO:0035272 162 0.064
protein complex biogenesis GO:0070271 201 0.063
photoreceptor cell differentiation GO:0046530 170 0.063
organophosphate biosynthetic process GO:0090407 46 0.062
lipid metabolic process GO:0006629 121 0.062
regulation of protein kinase activity GO:0045859 51 0.061
developmental programmed cell death GO:0010623 138 0.061
positive regulation of cell motility GO:2000147 3 0.060
dendrite development GO:0016358 204 0.060
columnar cuboidal epithelial cell differentiation GO:0002065 256 0.059
nucleoside phosphate metabolic process GO:0006753 162 0.059
hormone secretion GO:0046879 7 0.059
nucleoside phosphate catabolic process GO:1901292 110 0.058
response to organic cyclic compound GO:0014070 89 0.058
Rat
epithelial tube morphogenesis GO:0060562 88 0.058
Mouse
extrinsic apoptotic signaling pathway GO:0097191 1 0.058
single organism catabolic process GO:0044712 228 0.058
cellular amino acid metabolic process GO:0006520 61 0.057
organic anion transport GO:0015711 28 0.057
response to external biotic stimulus GO:0043207 293 0.057
glial cell migration GO:0008347 31 0.057
rna processing GO:0006396 147 0.056
response to wounding GO:0009611 94 0.056
male mating behavior GO:0060179 70 0.056
negative regulation of smoothened signaling pathway GO:0045879 16 0.056
stem cell proliferation GO:0072089 88 0.055
wnt signaling pathway GO:0016055 98 0.055
kidney development GO:0001822 3 0.055
peptide transport GO:0015833 10 0.055
organonitrogen compound biosynthetic process GO:1901566 117 0.055
regulation of cell differentiation GO:0045595 302 0.055
regulation of programmed cell death GO:0043067 152 0.055
positive regulation of developmental process GO:0051094 143 0.055
Worm
response to uv GO:0009411 24 0.054
response to organonitrogen compound GO:0010243 75 0.054
Rat
heart contraction GO:0060047 26 0.053
wound healing GO:0042060 75 0.053
response to mechanical stimulus GO:0009612 28 0.052
muscle cell development GO:0055001 50 0.052
branching morphogenesis of an epithelial tube GO:0048754 45 0.052
border follicle cell migration GO:0007298 113 0.051
germarium derived female germ line cyst encapsulation GO:0030708 8 0.051
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 116 0.051
nucleotide metabolic process GO:0009117 161 0.051
autophagy GO:0006914 108 0.051
male courtship behavior GO:0008049 63 0.051
proteolysis GO:0006508 192 0.051
Human
regulation of neurogenesis GO:0050767 158 0.050
embryonic development via the syncytial blastoderm GO:0001700 148 0.050
protein acetylation GO:0006473 39 0.050
protein targeting GO:0006605 64 0.050
protein acylation GO:0043543 42 0.049
organelle assembly GO:0070925 198 0.049
negative regulation of molecular function GO:0044092 51 0.049
regulation of tube size GO:0035150 46 0.048
neuron fate commitment GO:0048663 50 0.048
cellular response to organonitrogen compound GO:0071417 36 0.048
stress activated mapk cascade GO:0051403 52 0.048
protein transport GO:0015031 155 0.047
Mouse
regulation of cell migration GO:0030334 22 0.047
cardiovascular system development GO:0072358 82 0.047
imaginal disc derived leg segmentation GO:0036011 26 0.046
purine nucleotide metabolic process GO:0006163 146 0.046
purine containing compound catabolic process GO:0072523 112 0.046
mating GO:0007618 120 0.046
epidermis development GO:0008544 65 0.045
multicellular organism growth GO:0035264 46 0.045
stem cell development GO:0048864 79 0.045
cell junction assembly GO:0034329 42 0.045
Human
negative regulation of protein metabolic process GO:0051248 85 0.044
mesenchymal cell development GO:0014031 1 0.044
regulation of embryonic development GO:0045995 68 0.044
nephron tubule development GO:0072080 3 0.044
short term memory GO:0007614 19 0.044
digestive system development GO:0055123 149 0.044
Mouse
regulation of anatomical structure size GO:0090066 163 0.043
regulation of blood circulation GO:1903522 21 0.043
regulation of membrane potential GO:0042391 35 0.043
peptidyl threonine phosphorylation GO:0018107 2 0.043
Mouse
regulation of protein transport GO:0051223 57 0.043
Mouse
regulation of autophagy GO:0010506 62 0.042
phagocytosis GO:0006909 215 0.042
regulation of rna splicing GO:0043484 69 0.042
nucleoside metabolic process GO:0009116 127 0.042
skin development GO:0043588 65 0.041
embryo development ending in birth or egg hatching GO:0009792 152 0.041
Mouse
regulation of cell division GO:0051302 72 0.041
negative regulation of transferase activity GO:0051348 18 0.041
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 54 0.041
regulation of cellular response to stress GO:0080135 89 0.041
response to other organism GO:0051707 293 0.041
organ growth GO:0035265 56 0.041
dna integrity checkpoint GO:0031570 81 0.041
cell cycle phase transition GO:0044770 140 0.040
positive regulation of protein metabolic process GO:0051247 128 0.040
organic hydroxy compound metabolic process GO:1901615 83 0.040
hair cell differentiation GO:0035315 47 0.040
pole plasm rna localization GO:0007316 52 0.040
amide transport GO:0042886 10 0.040
kidney morphogenesis GO:0060993 3 0.039
membrane fusion GO:0061025 42 0.039
ribonucleoside triphosphate metabolic process GO:0009199 119 0.039
renal tubule development GO:0061326 64 0.038
negative regulation of sequence specific dna binding transcription factor activity GO:0043433 4 0.038
myotube differentiation GO:0014902 46 0.038
innate immune response activating signal transduction GO:0002758 2 0.038
regulation of hormone levels GO:0010817 40 0.037
negative regulation of programmed cell death GO:0043069 72 0.037
protein catabolic process GO:0030163 101 0.036
Human
regulation of protein localization to nucleus GO:1900180 29 0.036
internal peptidyl lysine acetylation GO:0018393 38 0.036
regulation of cytoplasmic transport GO:1903649 47 0.036
Mouse
adult behavior GO:0030534 137 0.036
purine ribonucleotide metabolic process GO:0009150 145 0.036
pole plasm mrna localization GO:0019094 49 0.035
regulation of intracellular signal transduction GO:1902531 236 0.034
negative regulation of mitotic cell cycle GO:0045930 109 0.034
neurotransmitter transport GO:0006836 37 0.034
non canonical wnt signaling pathway GO:0035567 8 0.034
ribonucleoside metabolic process GO:0009119 127 0.034
regulation of stem cell proliferation GO:0072091 40 0.033
gliogenesis GO:0042063 80 0.033
regulation of cell morphogenesis GO:0022604 163 0.033
histone acetylation GO:0016573 38 0.033
positive regulation of wnt signaling pathway GO:0030177 25 0.033
negative regulation of epidermal growth factor receptor signaling pathway GO:0042059 29 0.033
establishment of planar polarity GO:0001736 87 0.033
immune system development GO:0002520 57 0.033
nucleobase containing compound catabolic process GO:0034655 165 0.033
positive regulation of phosphate metabolic process GO:0045937 139 0.033
embryonic hindgut morphogenesis GO:0048619 48 0.033
hindgut morphogenesis GO:0007442 58 0.033
mesenchymal cell differentiation GO:0048762 1 0.032
cytokinesis GO:0000910 90 0.032
peptidyl amino acid modification GO:0018193 105 0.032
Human Mouse Rat
aromatic compound catabolic process GO:0019439 166 0.032
compound eye retinal cell programmed cell death GO:0046667 23 0.032
regulation of meiosis GO:0040020 3 0.032
regulation of jnk cascade GO:0046328 40 0.032
response to lipid GO:0033993 38 0.032
positive regulation of cellular protein metabolic process GO:0032270 118 0.032
nephron tubule morphogenesis GO:0072078 3 0.031
cellular response to oxygen containing compound GO:1901701 79 0.031
Human
cellular ketone metabolic process GO:0042180 24 0.031
necrotic cell death GO:0070265 1 0.031
negative regulation of multicellular organismal process GO:0051241 142 0.031
Mouse
intracellular protein transport GO:0006886 104 0.031
Mouse
response to biotic stimulus GO:0009607 294 0.031
response to lipopolysaccharide GO:0032496 4 0.030
rna splicing via transesterification reactions with bulged adenosine as nucleophile GO:0000377 73 0.030
translation GO:0006412 69 0.030
immune response activating signal transduction GO:0002757 2 0.030
response to hormone GO:0009725 45 0.030
Mouse
positive regulation of intracellular signal transduction GO:1902533 116 0.030
actin filament organization GO:0007015 126 0.029
nucleoside phosphate biosynthetic process GO:1901293 34 0.029
jnk cascade GO:0007254 50 0.029
regulation of circadian rhythm GO:0042752 49 0.029
peptidyl threonine modification GO:0018210 3 0.029
Mouse
myotube cell development GO:0014904 3 0.029
carbohydrate derivative biosynthetic process GO:1901137 85 0.029
regulation of intracellular protein transport GO:0033157 46 0.029
Mouse
positive regulation of mapk cascade GO:0043410 63 0.029
regulation of mitotic cell cycle phase transition GO:1901990 130 0.028
hematopoietic or lymphoid organ development GO:0048534 57 0.028
kidney epithelium development GO:0072073 3 0.028
negative regulation of cell cycle phase transition GO:1901988 103 0.028
positive regulation of programmed cell death GO:0043068 62 0.028
aging GO:0007568 143 0.028
stress activated protein kinase signaling cascade GO:0031098 55 0.028
negative regulation of mitotic cell cycle phase transition GO:1901991 103 0.028
histone h4 acetylation GO:0043967 13 0.028
regulation of intracellular transport GO:0032386 64 0.028
Mouse
intrinsic apoptotic signaling pathway in response to dna damage GO:0008630 11 0.027

Pka-C1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

Disease DO term ID Size Probability Func Analog Org
cancer DOID:162 0 0.054
disease of cellular proliferation DOID:14566 0 0.054
organ system cancer DOID:0050686 0 0.054
disease of anatomical entity DOID:7 0 0.035