Drosophila melanogaster

24 known processes

Hexo2 (Dmel_CG1787)

Hexosaminidase 2

(Aliases: Dmel\CG1787,DmHex2,CG1787,HEX 2,HEXO2,HEX2)

Hexo2 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
hormone catabolic process GO:0042447 3 0.087
regulation of multicellular organismal development GO:2000026 414 0.066
peptidyl proline modification GO:0018208 3 0.055
establishment of localization in cell GO:0051649 402 0.052
cellular catabolic process GO:0044248 372 0.051
vesicle mediated transport GO:0016192 381 0.044
catabolic process GO:0009056 409 0.043
growth GO:0040007 359 0.042
imaginal disc derived appendage development GO:0048737 399 0.041
estrogen metabolic process GO:0008210 1 0.037
kidney development GO:0001822 3 0.037
response to biotic stimulus GO:0009607 294 0.035
wing disc morphogenesis GO:0007472 344 0.034
positive regulation of multicellular organismal process GO:0051240 143 0.034
endocytosis GO:0006897 310 0.032
protein modification process GO:0036211 438 0.032
Fly
developmental growth GO:0048589 280 0.031
gland development GO:0048732 191 0.030
organic substance catabolic process GO:1901575 308 0.030
imaginal disc derived wing morphogenesis GO:0007476 337 0.029
regulation of developmental growth GO:0048638 174 0.029
body morphogenesis GO:0010171 2 0.029
small molecule metabolic process GO:0044281 305 0.027
single organism catabolic process GO:0044712 228 0.027
camera type eye development GO:0043010 4 0.026
response to abiotic stimulus GO:0009628 341 0.026
response to organic substance GO:0010033 284 0.026
response to other organism GO:0051707 293 0.026
organic substance transport GO:0071702 257 0.025
single organism behavior GO:0044708 391 0.025
organic cyclic compound catabolic process GO:1901361 168 0.025
lateral inhibition GO:0046331 206 0.025
positive regulation of developmental process GO:0051094 143 0.025
embryo development ending in birth or egg hatching GO:0009792 152 0.024
axonogenesis GO:0007409 290 0.024
positive regulation of response to stimulus GO:0048584 323 0.024
phagocytosis GO:0006909 215 0.023
ion transport GO:0006811 145 0.022
protein transport GO:0015031 155 0.022
protein localization GO:0008104 284 0.022
organic acid metabolic process GO:0006082 103 0.022
aromatic compound catabolic process GO:0019439 166 0.021
carbohydrate derivative metabolic process GO:1901135 217 0.021
Fly
defense response GO:0006952 300 0.021
cellular protein modification process GO:0006464 438 0.021
Fly
embryonic morphogenesis GO:0048598 206 0.021
cellular response to ethanol GO:0071361 4 0.021
axon development GO:0061564 297 0.021
appendage morphogenesis GO:0035107 397 0.021
carboxylic acid metabolic process GO:0019752 92 0.020
renal system development GO:0072001 72 0.020
urogenital system development GO:0001655 72 0.019
regulation of localization GO:0032879 275 0.019
morphogenesis of an epithelium GO:0002009 276 0.019
organonitrogen compound metabolic process GO:1901564 318 0.019
response to external biotic stimulus GO:0043207 293 0.019
transcription from rna polymerase ii promoter GO:0006366 368 0.019
androgen metabolic process GO:0008209 1 0.019
negative regulation of developmental process GO:0051093 201 0.018
cell motility GO:0048870 251 0.018
actin filament organization GO:0007015 126 0.018
neurological system process GO:0050877 358 0.018
cellular amino acid metabolic process GO:0006520 61 0.017
appendage development GO:0048736 401 0.017
oxoacid metabolic process GO:0043436 103 0.017
regionalization GO:0003002 416 0.017
brain development GO:0007420 120 0.017
Fly
post embryonic appendage morphogenesis GO:0035120 385 0.017
negative regulation of multicellular organismal process GO:0051241 142 0.017
heterocycle catabolic process GO:0046700 166 0.017
response to bacterium GO:0009617 198 0.017
response to alcohol GO:0097305 95 0.017
positive regulation of nitrogen compound metabolic process GO:0051173 354 0.017
neuron projection guidance GO:0097485 241 0.016
regulation of growth GO:0040008 233 0.016
proteolysis GO:0006508 192 0.016
positive regulation of biosynthetic process GO:0009891 316 0.016
imaginal disc derived appendage morphogenesis GO:0035114 395 0.016
connective tissue development GO:0061448 3 0.016
regulation of cellular component biogenesis GO:0044087 201 0.016
chemotaxis GO:0006935 249 0.016
positive regulation of developmental growth GO:0048639 62 0.016
forebrain development GO:0030900 2 0.016
defense response to bacterium GO:0042742 178 0.016
secretion GO:0046903 109 0.015
neuromuscular junction development GO:0007528 149 0.015
positive regulation of growth GO:0045927 75 0.015
germ band shortening GO:0007390 19 0.015
chemosensory behavior GO:0007635 106 0.015
spermatogenesis GO:0007283 200 0.015
regulation of anatomical structure size GO:0090066 163 0.015
organonitrogen compound catabolic process GO:1901565 128 0.015
cellular response to chemical stimulus GO:0070887 199 0.015
negative regulation of cellular metabolic process GO:0031324 382 0.015
regulation of response to stress GO:0080134 200 0.015
positive regulation of cell communication GO:0010647 250 0.015
macromolecular complex assembly GO:0065003 256 0.014
lipid catabolic process GO:0016042 21 0.014
cellular nitrogen compound catabolic process GO:0044270 165 0.014
response to lipopolysaccharide GO:0032496 4 0.014
response to oxygen containing compound GO:1901700 200 0.014
regulation of anatomical structure morphogenesis GO:0022603 242 0.014
axon guidance GO:0007411 233 0.014
cell cell signaling involved in cell fate commitment GO:0045168 210 0.014
lipid metabolic process GO:0006629 121 0.014
regulation of molecular function GO:0065009 217 0.014
positive regulation of cellular biosynthetic process GO:0031328 316 0.014
intracellular transport GO:0046907 228 0.014
intracellular protein transport GO:0006886 104 0.014
intracellular signal transduction GO:0035556 300 0.013
establishment of protein localization GO:0045184 163 0.013
retina development in camera type eye GO:0060041 4 0.013
secretion by cell GO:0032940 101 0.013
eye morphogenesis GO:0048592 260 0.013
nephron development GO:0072006 3 0.013
synapse organization GO:0050808 196 0.013
spermatid differentiation GO:0048515 114 0.013
cellular lipid metabolic process GO:0044255 83 0.013
cellular macromolecule localization GO:0070727 220 0.013
spindle organization GO:0007051 253 0.013
single organism carbohydrate metabolic process GO:0044723 72 0.013
Fly
negative regulation of gene expression GO:0010629 387 0.013
positive regulation of macromolecule metabolic process GO:0010604 405 0.013
regulation of catalytic activity GO:0050790 185 0.013
steroid catabolic process GO:0006706 1 0.012
cellular amide metabolic process GO:0043603 80 0.012
positive regulation of nucleobase containing compound metabolic process GO:0045935 332 0.012
regulation of cell differentiation GO:0045595 302 0.012
purine nucleotide metabolic process GO:0006163 146 0.012
cell proliferation GO:0008283 299 0.012
male gamete generation GO:0048232 201 0.012
cellular amine metabolic process GO:0044106 12 0.012
extracellular structure organization GO:0043062 46 0.012
regulation of multicellular organism growth GO:0040014 40 0.012
positive regulation of signaling GO:0023056 243 0.012
defense response to other organism GO:0098542 225 0.012
immune system process GO:0002376 347 0.012
amine metabolic process GO:0009308 12 0.012
membrane organization GO:0061024 112 0.012
regulation of protein localization GO:0032880 76 0.012
regulation of cellular ketone metabolic process GO:0010565 3 0.012
head development GO:0060322 135 0.011
Fly
regulation of transcription from rna polymerase ii promoter GO:0006357 378 0.011
regulation of notch signaling pathway GO:0008593 100 0.011
positive regulation of transcription dna templated GO:0045893 266 0.011
nucleobase containing compound catabolic process GO:0034655 165 0.011
eye development GO:0001654 323 0.011
multi organism reproductive behavior GO:0044705 121 0.011
cell migration GO:0016477 238 0.011
cell death GO:0008219 279 0.011
actin cytoskeleton organization GO:0030036 206 0.011
response to nutrient levels GO:0031667 114 0.011
regulation of protein metabolic process GO:0051246 256 0.011
regulation of cellular protein metabolic process GO:0032268 243 0.011
hindgut development GO:0061525 58 0.011
cell division GO:0051301 248 0.011
ras protein signal transduction GO:0007265 88 0.011
compound eye morphogenesis GO:0001745 249 0.011
antimicrobial humoral response GO:0019730 99 0.011
response to starvation GO:0042594 97 0.011
l amino acid import GO:0043092 2 0.011
exocrine system development GO:0035272 162 0.011
purine containing compound metabolic process GO:0072521 155 0.011
tissue morphogenesis GO:0048729 297 0.011
l glutamate import GO:0051938 1 0.011
central nervous system development GO:0007417 201 0.011
Fly
purine nucleoside metabolic process GO:0042278 127 0.011
positive regulation of rna biosynthetic process GO:1902680 266 0.010
regulation of gene expression epigenetic GO:0040029 128 0.010
peptidyl proline hydroxylation GO:0019511 1 0.010
multi organism behavior GO:0051705 175 0.010
embryonic development via the syncytial blastoderm GO:0001700 148 0.010
positive regulation of nucleic acid templated transcription GO:1903508 266 0.010
positive regulation of rna metabolic process GO:0051254 271 0.010
endomembrane system organization GO:0010256 119 0.010

Hexo2 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.044
nervous system disease DOID:863 0 0.015
disease of metabolism DOID:0014667 0 0.014
central nervous system disease DOID:331 0 0.012
musculoskeletal system disease DOID:17 0 0.010