Drosophila melanogaster

158 known processes

Sin3A (Dmel_CG8815)

CG8815 gene product from transcript CG8815-RC

(Aliases: dSin3,l(2)k05415,dSin3A,sin3,Sin3,Sin 3A,27/3,ESTS:159A11T,l(2)08269,Sin3a,ld,Dmel\CG8815,sin3A,l(2)k02703,SIN3A,EY2-9,l(2)k09715,sni3,159A11T,CG8815,ES2-3,SIN3,97/15)

Sin3A biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
regulation of transcription from rna polymerase ii promoter GO:0006357 378 0.990
Human Mouse
tor signaling GO:0031929 32 0.909
positive regulation of nitrogen compound metabolic process GO:0051173 354 0.860
Human
positive regulation of response to stimulus GO:0048584 323 0.830
Human
hemopoiesis GO:0030097 46 0.768
Mouse
cell motility GO:0048870 251 0.767
apoptotic process GO:0006915 159 0.761
Mouse
negative regulation of transcription from rna polymerase ii promoter GO:0000122 119 0.759
Human Mouse
positive regulation of protein metabolic process GO:0051247 128 0.751
stem cell differentiation GO:0048863 117 0.736
positive regulation of phosphate metabolic process GO:0045937 139 0.734
cellular response to dna damage stimulus GO:0006974 223 0.729
stem cell maintenance GO:0019827 67 0.725
eye morphogenesis GO:0048592 260 0.709
intracellular signal transduction GO:0035556 300 0.698
positive regulation of macromolecule metabolic process GO:0010604 405 0.694
Human
regionalization GO:0003002 416 0.689
regulation of kinase activity GO:0043549 53 0.686
protein phosphorylation GO:0006468 169 0.665
regulation of phosphorylation GO:0042325 147 0.661
negative regulation of transcription dna templated GO:0045892 237 0.660
negative regulation of cell communication GO:0010648 223 0.655
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 116 0.652
negative regulation of nitrogen compound metabolic process GO:0051172 265 0.629
positive regulation of cellular biosynthetic process GO:0031328 316 0.623
Human
negative regulation of signal transduction GO:0009968 206 0.623
regulation of protein metabolic process GO:0051246 256 0.619
Human
positive regulation of transcription dna templated GO:0045893 266 0.608
Human
cell migration GO:0016477 238 0.604
phosphorylation GO:0016310 294 0.602
regulation of response to stress GO:0080134 200 0.583
Human
positive regulation of transcription from rna polymerase ii promoter GO:0045944 204 0.564
Human
transcription from rna polymerase ii promoter GO:0006366 368 0.558
Human Mouse
positive regulation of cellular protein metabolic process GO:0032270 118 0.556
cellular protein modification process GO:0006464 438 0.555
Human Worm
catabolic process GO:0009056 409 0.546
tube development GO:0035295 244 0.534
multicellular organismal aging GO:0010259 140 0.532
positive regulation of molecular function GO:0044093 136 0.530
positive regulation of signal transduction GO:0009967 223 0.529
endocytosis GO:0006897 310 0.498
regulation of anatomical structure morphogenesis GO:0022603 242 0.492
respiratory system development GO:0060541 213 0.491
negative regulation of cellular metabolic process GO:0031324 382 0.484
negative regulation of rna metabolic process GO:0051253 251 0.477
negative regulation of apoptotic process GO:0043066 63 0.460
Mouse
dorsal ventral pattern formation GO:0009953 133 0.448
imaginal disc derived wing vein morphogenesis GO:0008586 44 0.430
regulation of protein kinase activity GO:0045859 51 0.421
central nervous system development GO:0007417 201 0.413
negative regulation of cellular biosynthetic process GO:0031327 277 0.411
enzyme linked receptor protein signaling pathway GO:0007167 179 0.398
regulation of transport GO:0051049 181 0.390
positive regulation of phosphorus metabolic process GO:0010562 139 0.390
vesicle mediated transport GO:0016192 381 0.381
regulation of catalytic activity GO:0050790 185 0.377
compound eye development GO:0048749 307 0.372
regulation of cellular catabolic process GO:0031329 157 0.357
defense response to other organism GO:0098542 225 0.355
Human
stem cell development GO:0048864 79 0.350
immune response GO:0006955 246 0.347
Human
nucleobase containing compound catabolic process GO:0034655 165 0.339
protein modification process GO:0036211 438 0.332
Human Worm
cardiovascular system development GO:0072358 82 0.325
Mouse
positive regulation of macromolecule biosynthetic process GO:0010557 283 0.321
Human
biological adhesion GO:0022610 138 0.320
purine ribonucleoside metabolic process GO:0046128 127 0.318
cellular response to chemical stimulus GO:0070887 199 0.316
Mouse
response to radiation GO:0009314 155 0.307
embryo development ending in birth or egg hatching GO:0009792 152 0.303
Mouse Worm
cell growth GO:0016049 108 0.294
multicellular organismal reproductive behavior GO:0033057 110 0.291
response to organic substance GO:0010033 284 0.289
Mouse
positive regulation of rna metabolic process GO:0051254 271 0.287
Human
cellular response to abiotic stimulus GO:0071214 58 0.276
regulation of catabolic process GO:0009894 170 0.274
mitotic cell cycle phase transition GO:0044772 138 0.272
Mouse
positive regulation of biosynthetic process GO:0009891 316 0.260
Human
cellular response to radiation GO:0071478 52 0.259
cell fate specification GO:0001708 71 0.258
Worm
cellular catabolic process GO:0044248 372 0.257
stress activated mapk cascade GO:0051403 52 0.254
negative regulation of nucleic acid templated transcription GO:1903507 240 0.251
positive regulation of protein kinase activity GO:0045860 25 0.248
regulation of phosphorus metabolic process GO:0051174 210 0.240
positive regulation of signaling GO:0023056 243 0.239
regulation of organelle organization GO:0033043 196 0.238
Human
negative regulation of glial cell proliferation GO:0060253 6 0.237
negative regulation of cell cycle phase transition GO:1901988 103 0.233
positive regulation of phosphorylation GO:0042327 87 0.232
dna metabolic process GO:0006259 227 0.229
Mouse
muscle cell differentiation GO:0042692 103 0.227
reproductive system development GO:0061458 74 0.225
sensory organ morphogenesis GO:0090596 260 0.222
regulation of phosphate metabolic process GO:0019220 210 0.222
negative regulation of signaling GO:0023057 219 0.221
negative regulation of cell death GO:0060548 81 0.219
Mouse
negative regulation of rna biosynthetic process GO:1902679 240 0.218
negative regulation of response to stimulus GO:0048585 258 0.214
epithelial cell migration GO:0010631 148 0.214
positive regulation of protein phosphorylation GO:0001934 34 0.213
regulation of cellular amino acid metabolic process GO:0006521 0 0.211
positive regulation of cellular response to insulin stimulus GO:1900078 4 0.206
immune response activating signal transduction GO:0002757 2 0.206
regulation of intracellular signal transduction GO:1902531 236 0.204
programmed cell death GO:0012501 257 0.203
Mouse
cellular response to oxygen containing compound GO:1901701 79 0.201
Mouse
cell death GO:0008219 279 0.200
Mouse
mitochondrion organization GO:0007005 65 0.199
autophagy GO:0006914 108 0.197
negative regulation of gene expression GO:0010629 387 0.193
localization of cell GO:0051674 257 0.192
aging GO:0007568 143 0.191
negative regulation of transferase activity GO:0051348 18 0.191
cell proliferation GO:0008283 299 0.190
negative regulation of kinase activity GO:0033673 16 0.186
digestive tract development GO:0048565 149 0.183
positive regulation of cellular catabolic process GO:0031331 95 0.177
camera type eye development GO:0043010 4 0.174
regulation of mitotic cell cycle GO:0007346 190 0.170
positive regulation of protein modification process GO:0031401 58 0.168
negative regulation of cellular macromolecule biosynthetic process GO:2000113 267 0.165
negative regulation of programmed cell death GO:0043069 72 0.160
Mouse
single organism behavior GO:0044708 391 0.157
regulation of map kinase activity GO:0043405 17 0.156
cellular response to endogenous stimulus GO:0071495 80 0.155
eye development GO:0001654 323 0.155
locomotory behavior GO:0007626 176 0.155
positive regulation of gene expression GO:0010628 290 0.154
Human
regulation of cell morphogenesis GO:0022604 163 0.152
regulation of protein modification process GO:0031399 112 0.150
Human
positive regulation of cellular component organization GO:0051130 156 0.150
regulation of cell cycle process GO:0010564 181 0.149
Mouse
regulation of transferase activity GO:0051338 58 0.146
defense response to gram negative bacterium GO:0050829 94 0.146
regulation of programmed cell death GO:0043067 152 0.146
Mouse
regulation of glial cell proliferation GO:0060251 11 0.145
ameboidal type cell migration GO:0001667 151 0.144
regulation of cellular protein metabolic process GO:0032268 243 0.142
Human
positive regulation of catabolic process GO:0009896 105 0.142
germ line stem cell maintenance GO:0030718 50 0.141
regulation of protein serine threonine kinase activity GO:0071900 25 0.141
organ growth GO:0035265 56 0.139
positive regulation of organelle organization GO:0010638 65 0.137
homeostatic process GO:0042592 199 0.137
Mouse
cellular response to organic substance GO:0071310 132 0.137
Mouse
nucleus organization GO:0006997 45 0.136
body morphogenesis GO:0010171 2 0.136
negative regulation of nucleobase containing compound metabolic process GO:0045934 261 0.135
protein localization to organelle GO:0033365 82 0.135
Human
regulation of apoptotic process GO:0042981 130 0.134
Mouse
regulation of cell death GO:0010941 173 0.133
Mouse
renal system development GO:0072001 72 0.133
negative regulation of phosphorylation GO:0042326 35 0.130
regulation of protein phosphorylation GO:0001932 64 0.124
response to abiotic stimulus GO:0009628 341 0.123
tissue migration GO:0090130 155 0.123
ribonucleoside catabolic process GO:0042454 112 0.122
regulation of cellular ketone metabolic process GO:0010565 3 0.122
response to other organism GO:0051707 293 0.119
Human
positive regulation of rna biosynthetic process GO:1902680 266 0.118
Human
appendage development GO:0048736 401 0.118
ras protein signal transduction GO:0007265 88 0.116
negative regulation of cell differentiation GO:0045596 143 0.114
neural precursor cell proliferation GO:0061351 75 0.113
positive regulation of immune system process GO:0002684 68 0.112
Human
cellular response to nitrogen compound GO:1901699 51 0.112
cell adhesion GO:0007155 136 0.111
negative regulation of cell proliferation GO:0008285 69 0.110
guanosine containing compound catabolic process GO:1901069 74 0.110
morphogenesis of an epithelium GO:0002009 276 0.110
neurological system process GO:0050877 358 0.109
gliogenesis GO:0042063 80 0.109
mapk cascade GO:0000165 107 0.108
organophosphate metabolic process GO:0019637 195 0.105
regulation of immune system process GO:0002682 176 0.104
compound eye photoreceptor cell differentiation GO:0001751 140 0.102
death GO:0016265 284 0.101
Mouse
regulation of dna metabolic process GO:0051052 34 0.101
positive regulation of hydrolase activity GO:0051345 78 0.101
appendage morphogenesis GO:0035107 397 0.099
urogenital system development GO:0001655 72 0.097
nucleotide catabolic process GO:0009166 109 0.097
histone h3 k9 acetylation GO:0043970 3 0.097
determination of adult lifespan GO:0008340 137 0.096
regulation of immune response GO:0050776 118 0.096
Human
malpighian tubule morphogenesis GO:0007443 44 0.096
positive regulation of multicellular organismal process GO:0051240 143 0.094
regulation of chromosome organization GO:0033044 64 0.093
Human
embryonic organ development GO:0048568 50 0.093
small gtpase mediated signal transduction GO:0007264 88 0.091
regulation of cell cycle phase transition GO:1901987 130 0.091
Mouse
regulation of cell differentiation GO:0045595 302 0.090
nucleoside metabolic process GO:0009116 127 0.090
cell proliferation involved in imaginal disc derived wing morphogenesis GO:0090255 2 0.089
dna damage checkpoint GO:0000077 78 0.085
defense response to bacterium GO:0042742 178 0.085
response to bacterium GO:0009617 198 0.084
carbohydrate derivative catabolic process GO:1901136 118 0.084
positive regulation of nucleoside metabolic process GO:0045979 47 0.083
small molecule metabolic process GO:0044281 305 0.082
negative regulation of intracellular signal transduction GO:1902532 57 0.081
cellular nitrogen compound catabolic process GO:0044270 165 0.081
regulation of neural precursor cell proliferation GO:2000177 35 0.079
tissue morphogenesis GO:0048729 297 0.078
positive regulation of cell communication GO:0010647 250 0.078
somatic stem cell maintenance GO:0035019 14 0.077
growth GO:0040007 359 0.075
positive regulation of transferase activity GO:0051347 26 0.074
positive regulation of kinase activity GO:0033674 25 0.074
protein localization to nucleus GO:0034504 55 0.073
Human
multi organism reproductive behavior GO:0044705 121 0.073
embryonic development via the syncytial blastoderm GO:0001700 148 0.072
regulation of cellular response to stress GO:0080135 89 0.072
protein targeting to nucleus GO:0044744 51 0.071
circulatory system development GO:0072359 82 0.071
Mouse
chromatin silencing GO:0006342 76 0.069
Human
positive regulation of catalytic activity GO:0043085 118 0.069
tube morphogenesis GO:0035239 191 0.069
regulation of mapk cascade GO:0043408 92 0.068
humoral immune response GO:0006959 117 0.067
organic cyclic compound catabolic process GO:1901361 168 0.067
aromatic compound catabolic process GO:0019439 166 0.067
signal transduction in response to dna damage GO:0042770 3 0.067
gene silencing GO:0016458 138 0.067
Human Worm
organic substance catabolic process GO:1901575 308 0.067
synaptic transmission GO:0007268 288 0.066
stem cell proliferation GO:0072089 88 0.065
hematopoietic or lymphoid organ development GO:0048534 57 0.062
Mouse
regulation of cell cycle GO:0051726 291 0.061
regulation of cell growth GO:0001558 43 0.061
mitochondrial fission GO:0000266 8 0.060
immune system development GO:0002520 57 0.060
Mouse
guanosine containing compound metabolic process GO:1901068 74 0.059
negative regulation of mitotic cell cycle phase transition GO:1901991 103 0.058
regulation of nucleoside metabolic process GO:0009118 50 0.057
regulation of gtpase activity GO:0043087 44 0.057
cell cycle checkpoint GO:0000075 95 0.057
response to biotic stimulus GO:0009607 294 0.057
Human
heterocycle catabolic process GO:0046700 166 0.056
histone h2a ubiquitination GO:0033522 2 0.056
positive regulation of gtpase activity GO:0043547 43 0.056
rna processing GO:0006396 147 0.055
regulation of cellular response to insulin stimulus GO:1900076 17 0.054
regulation of molecular function GO:0065009 217 0.054
Human
positive regulation of intracellular signal transduction GO:1902533 116 0.054
defense response to fungus GO:0050832 48 0.054
negative regulation of developmental process GO:0051093 201 0.053
Worm
regulation of cell proliferation GO:0042127 163 0.052
cellular ketone metabolic process GO:0042180 24 0.052
purine nucleoside metabolic process GO:0042278 127 0.051
telencephalon development GO:0021537 2 0.051
photoreceptor cell differentiation GO:0046530 170 0.050
cellular response to organonitrogen compound GO:0071417 36 0.050
purine containing compound catabolic process GO:0072523 112 0.049
positive regulation of nucleotide catabolic process GO:0030813 46 0.049
neuron projection guidance GO:0097485 241 0.048
stress activated protein kinase signaling cascade GO:0031098 55 0.048
regulation of ras gtpase activity GO:0032318 38 0.048
ribonucleotide catabolic process GO:0009261 109 0.047
endodermal cell differentiation GO:0035987 3 0.047
single organism nuclear import GO:1902593 51 0.046
positive regulation of nucleic acid templated transcription GO:1903508 266 0.046
Human
response to sterol GO:0036314 34 0.046
chromatin modification GO:0016568 147 0.046
Human Worm
chromosome organization GO:0051276 360 0.046
Human Worm
negative regulation of transforming growth factor beta receptor signaling pathway GO:0030512 4 0.046
response to endogenous stimulus GO:0009719 119 0.046
negative regulation of phosphate metabolic process GO:0045936 45 0.045
cell elongation involved in imaginal disc derived wing morphogenesis GO:0090254 5 0.045
mitotic nuclear division GO:0007067 213 0.045
compound eye morphogenesis GO:0001745 249 0.045
apoptotic signaling pathway GO:0097190 27 0.045
post embryonic appendage morphogenesis GO:0035120 385 0.045
regulation of apoptotic signaling pathway GO:2001233 10 0.045
gtp metabolic process GO:0046039 72 0.045
regulation of chromatin organization GO:1902275 32 0.044
Human
positive regulation of transport GO:0051050 92 0.044
unidimensional cell growth GO:0009826 15 0.044
protein import into nucleus GO:0006606 51 0.044
retina development in camera type eye GO:0060041 4 0.044
intrinsic apoptotic signaling pathway GO:0097193 16 0.043
regulation of purine nucleotide catabolic process GO:0033121 48 0.043
negative regulation of protein metabolic process GO:0051248 85 0.043
Human
cellular response to insulin stimulus GO:0032869 28 0.043
sex differentiation GO:0007548 81 0.042
Worm
amine metabolic process GO:0009308 12 0.042
chemosensory behavior GO:0007635 106 0.042
positive regulation of nucleobase containing compound metabolic process GO:0045935 332 0.042
Human
regulation of nervous system development GO:0051960 248 0.042
antifungal peptide biosynthetic process GO:0002783 5 0.042
negative regulation of cell cycle GO:0045786 116 0.041
spermatid development GO:0007286 98 0.041
purine nucleoside catabolic process GO:0006152 112 0.041
negative regulation of protein phosphorylation GO:0001933 17 0.041
regulation of histone modification GO:0031056 20 0.040
Human
neuron death GO:0070997 27 0.040
response to growth factor GO:0070848 31 0.040
mushroom body development GO:0016319 70 0.040
purine nucleoside triphosphate metabolic process GO:0009144 119 0.040
epithelium migration GO:0090132 148 0.040
purine nucleotide catabolic process GO:0006195 109 0.040
defense response GO:0006952 300 0.039
Human
gtp catabolic process GO:0006184 72 0.039
embryonic heart tube development GO:0035050 22 0.038
glycosyl compound catabolic process GO:1901658 112 0.038
organonitrogen compound catabolic process GO:1901565 128 0.038
maintenance of location in cell GO:0051651 28 0.037
protein targeting GO:0006605 64 0.037
purine ribonucleoside triphosphate metabolic process GO:0009205 119 0.037
histone modification GO:0016570 106 0.037
Human Worm
regulation of neuron apoptotic process GO:0043523 16 0.037
embryonic hemopoiesis GO:0035162 26 0.037
response to alcohol GO:0097305 95 0.037
bmp signaling pathway involved in malpighian tubule cell chemotaxis GO:0061353 3 0.037
negative regulation of neural precursor cell proliferation GO:2000178 27 0.036
negative regulation of cellular protein metabolic process GO:0032269 85 0.036
Human
connective tissue development GO:0061448 3 0.036
jak stat cascade GO:0007259 49 0.036
blastoderm segmentation GO:0007350 159 0.036
reproductive structure development GO:0048608 74 0.036
histone lysine demethylation GO:0070076 6 0.035
response to oxygen containing compound GO:1901700 200 0.035
Mouse
regulation of cell proliferation involved in imaginal disc derived wing morphogenesis GO:0090256 2 0.035
regulation of jnk cascade GO:0046328 40 0.035
purine ribonucleotide catabolic process GO:0009154 109 0.035
positive regulation of developmental growth GO:0048639 62 0.034
nucleocytoplasmic transport GO:0006913 72 0.034
heart process GO:0003015 37 0.034
axon guidance GO:0007411 233 0.034
positive regulation of apoptotic process GO:0043065 47 0.034
regulation of protein import into nucleus GO:0042306 28 0.034
mitotic sister chromatid segregation GO:0000070 87 0.034
wing disc morphogenesis GO:0007472 344 0.034
regulation of proteolysis GO:0030162 87 0.034
embryonic hindgut morphogenesis GO:0048619 48 0.033
nucleoside phosphate catabolic process GO:1901292 110 0.033
negative regulation of neurogenesis GO:0050768 53 0.033
regulation of neuron death GO:1901214 26 0.033
cell cell signaling involved in cell fate commitment GO:0045168 210 0.033
establishment of protein localization to organelle GO:0072594 62 0.033
regulation of membrane potential GO:0042391 35 0.032
nucleoside triphosphate metabolic process GO:0009141 120 0.032
antimicrobial humoral response GO:0019730 99 0.032
regulation of stress activated mapk cascade GO:0032872 41 0.032
regulation of hydrolase activity GO:0051336 97 0.032
regulation of notch signaling pathway GO:0008593 100 0.031
negative regulation of mitotic cell cycle GO:0045930 109 0.031
ribonucleoside triphosphate metabolic process GO:0009199 119 0.031
spinal cord development GO:0021510 1 0.031
chromatin organization GO:0006325 207 0.031
Human Worm
imaginal disc pattern formation GO:0007447 91 0.031
imaginal disc derived wing morphogenesis GO:0007476 337 0.031
positive regulation of gtp catabolic process GO:0033126 43 0.031
regulation of defense response GO:0031347 102 0.031
Human
nucleolus organization GO:0007000 4 0.031
signal transduction by phosphorylation GO:0023014 107 0.031
ncrna metabolic process GO:0034660 43 0.031
actin mediated cell contraction GO:0070252 21 0.031
muscle structure development GO:0061061 224 0.030
phagocytosis GO:0006909 215 0.030
nucleoside catabolic process GO:0009164 112 0.030
cell division GO:0051301 248 0.030
pigmentation GO:0043473 75 0.029
endodermal cell fate commitment GO:0001711 3 0.029
digestive tract morphogenesis GO:0048546 127 0.029
establishment of protein localization GO:0045184 163 0.029
positive regulation of cell differentiation GO:0045597 64 0.029
development of primary sexual characteristics GO:0045137 50 0.029
response to monosaccharide GO:0034284 4 0.029
Mouse
regulation of cell junction assembly GO:1901888 2 0.029
cognition GO:0050890 141 0.029
protein modification by small protein conjugation or removal GO:0070647 106 0.028
negative regulation of phosphorus metabolic process GO:0010563 45 0.028
cilium morphogenesis GO:0060271 39 0.028
jnk cascade GO:0007254 50 0.027
learning or memory GO:0007611 141 0.027
cell cell junction organization GO:0045216 55 0.027
covalent chromatin modification GO:0016569 106 0.027
Human Worm
regulation of cellular component biogenesis GO:0044087 201 0.027
establishment of planar polarity GO:0001736 87 0.027
response to oxidative stress GO:0006979 86 0.026
negative regulation of cellular response to oxidative stress GO:1900408 1 0.026
cell fate determination GO:0001709 91 0.026
multi organism behavior GO:0051705 175 0.026
embryonic pattern specification GO:0009880 174 0.026
glial cell differentiation GO:0010001 35 0.026
malpighian tubule development GO:0072002 64 0.026
macromolecule catabolic process GO:0009057 161 0.026
regulation of cellular localization GO:0060341 136 0.026
Human
response to light stimulus GO:0009416 124 0.026
negative regulation of mapk cascade GO:0043409 23 0.026
brain development GO:0007420 120 0.025
muscle organ development GO:0007517 127 0.025
organonitrogen compound metabolic process GO:1901564 318 0.025
regulation of mitosis GO:0007088 56 0.025
organic acid metabolic process GO:0006082 103 0.025
regulation of epithelial cell differentiation GO:0030856 4 0.025
carbohydrate derivative metabolic process GO:1901135 217 0.025
response to heat GO:0009408 63 0.025
multicellular organismal homeostasis GO:0048871 41 0.025
maintenance of gastrointestinal epithelium GO:0030277 3 0.024
intraspecies interaction between organisms GO:0051703 4 0.024
camera type eye morphogenesis GO:0048593 2 0.024
regulation of localization GO:0032879 275 0.024
positive regulation of pathway restricted smad protein phosphorylation GO:0010862 1 0.024
embryonic morphogenesis GO:0048598 206 0.024
hematopoietic progenitor cell differentiation GO:0002244 1 0.023
Mouse
wing disc pattern formation GO:0035222 66 0.023
regulation of nucleotide metabolic process GO:0006140 62 0.023
mrna metabolic process GO:0016071 124 0.023
cellular amino acid metabolic process GO:0006520 61 0.023
mesenchymal cell development GO:0014031 1 0.023
regulation of nucleotide catabolic process GO:0030811 48 0.023
positive regulation of multicellular organism growth GO:0040018 21 0.022
imaginal disc derived leg morphogenesis GO:0007480 80 0.022
epithelial cell development GO:0002064 274 0.022
g2 dna damage checkpoint GO:0031572 69 0.022
compound eye cone cell differentiation GO:0042675 13 0.022
immune system process GO:0002376 347 0.022
positive regulation of cellular component biogenesis GO:0044089 80 0.022
mesenchymal cell differentiation GO:0048762 1 0.022
protein transport GO:0015031 155 0.022
axis specification GO:0009798 167 0.021
regulation of cell shape GO:0008360 113 0.021
skin development GO:0043588 65 0.021
cell type specific apoptotic process GO:0097285 38 0.021
taxis GO:0042330 304 0.021
regulation of protein targeting GO:1903533 29 0.021
ribonucleoside triphosphate catabolic process GO:0009203 108 0.021
positive regulation of nucleotide metabolic process GO:0045981 55 0.021
regulation of stem cell proliferation GO:0072091 40 0.020
forebrain development GO:0030900 2 0.020
organic substance transport GO:0071702 257 0.020
regulation of chromatin modification GO:1903308 28 0.020
Human
regulation of pathway restricted smad protein phosphorylation GO:0060393 1 0.020
imaginal disc derived appendage morphogenesis GO:0035114 395 0.020
germline ring canal formation GO:0030725 13 0.020
positive regulation of cell death GO:0010942 69 0.020
regulation of cellular amine metabolic process GO:0033238 3 0.020
imaginal disc derived appendage development GO:0048737 399 0.020
negative regulation of epithelial cell proliferation GO:0050680 4 0.020
regulation of hormone levels GO:0010817 40 0.020
response to external biotic stimulus GO:0043207 293 0.020
Human
regulation of stress activated protein kinase signaling cascade GO:0070302 42 0.020
positive regulation of cell motility GO:2000147 3 0.020
cell cycle phase transition GO:0044770 140 0.019
Mouse
tissue homeostasis GO:0001894 36 0.019
axon development GO:0061564 297 0.019
spermatogenesis GO:0007283 200 0.019
muscle system process GO:0003012 21 0.019
positive regulation of programmed cell death GO:0043068 62 0.019
negative regulation of molecular function GO:0044092 51 0.019
Human
kidney development GO:0001822 3 0.019
positive regulation of cell migration GO:0030335 2 0.019
positive regulation of jun kinase activity GO:0043507 4 0.019
nuclear import GO:0051170 51 0.019
endomembrane system organization GO:0010256 119 0.019
spindle organization GO:0007051 253 0.018
convergent extension GO:0060026 2 0.018
negative regulation of macromolecule biosynthetic process GO:0010558 270 0.018
purine ribonucleotide metabolic process GO:0009150 145 0.018
regulation of ion transport GO:0043269 39 0.018
cellular response to organic cyclic compound GO:0071407 32 0.018
regulation of neuron differentiation GO:0045664 103 0.018
head development GO:0060322 135 0.018
posttranscriptional gene silencing GO:0016441 46 0.018
Worm
organelle fission GO:0048285 340 0.018
blood circulation GO:0008015 26 0.018
morphogenesis of embryonic epithelium GO:0016331 94 0.018
larval development GO:0002164 104 0.018
Worm
dna integrity checkpoint GO:0031570 81 0.018
regulation of tor signaling GO:0032006 21 0.017
meiotic cell cycle GO:0051321 171 0.017
intracellular transport GO:0046907 228 0.017
interspecies interaction between organisms GO:0044419 16 0.017
sensory perception GO:0007600 196 0.017
epidermal growth factor receptor signaling pathway GO:0007173 58 0.017
regulation of intracellular protein transport GO:0033157 46 0.017
negative regulation of protein kinase activity GO:0006469 15 0.017
regulation of small gtpase mediated signal transduction GO:0051056 93 0.017
regulation of vesicle mediated transport GO:0060627 59 0.017
cellular protein localization GO:0034613 160 0.017
Human Mouse
positive regulation of protein serine threonine kinase activity GO:0071902 15 0.017
positive regulation of defense response GO:0031349 59 0.017
Human
eye photoreceptor cell differentiation GO:0001754 145 0.017
multi multicellular organism process GO:0044706 123 0.017

Sin3A disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.127
cardiovascular system disease DOID:1287 0 0.127
large intestine cancer DOID:5672 0 0.107
gastrointestinal system cancer DOID:3119 0 0.107
intestinal cancer DOID:10155 0 0.107
cancer DOID:162 0 0.107
disease of cellular proliferation DOID:14566 0 0.107
organ system cancer DOID:0050686 0 0.107
colorectal cancer DOID:9256 0 0.107