Drosophila melanogaster

47 known processes

CG42674 (Dmel_CG42674)

CG42674 gene product from transcript CG42674-RE

(Aliases: CG42348,Dmel_CG13811,CG7323,Dmel_CG7323,CG13812,Dmel\CG42674,CG13811,Dmel_CG42348,Dmel_CG32223,CG32223)

CG42674 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
negative regulation of gene expression GO:0010629 387 0.060
organonitrogen compound metabolic process GO:1901564 318 0.051
cell proliferation GO:0008283 299 0.051
ion transport GO:0006811 145 0.047
cell division GO:0051301 248 0.041
establishment of localization in cell GO:0051649 402 0.040
cell death GO:0008219 279 0.040
response to external biotic stimulus GO:0043207 293 0.040
regulation of multicellular organismal development GO:2000026 414 0.038
nucleobase containing small molecule metabolic process GO:0055086 174 0.038
regulation of cell differentiation GO:0045595 302 0.036
posttranscriptional regulation of gene expression GO:0010608 145 0.035
positive regulation of cell communication GO:0010647 250 0.034
response to other organism GO:0051707 293 0.034
tissue morphogenesis GO:0048729 297 0.033
transcription from rna polymerase ii promoter GO:0006366 368 0.032
negative regulation of macromolecule biosynthetic process GO:0010558 270 0.032
catabolic process GO:0009056 409 0.032
positive regulation of signaling GO:0023056 243 0.031
defense response GO:0006952 300 0.031
response to biotic stimulus GO:0009607 294 0.031
protein phosphorylation GO:0006468 169 0.031
response to temperature stimulus GO:0009266 106 0.030
response to organic substance GO:0010033 284 0.030
small molecule metabolic process GO:0044281 305 0.030
carboxylic acid metabolic process GO:0019752 92 0.030
protein localization GO:0008104 284 0.030
positive regulation of response to stimulus GO:0048584 323 0.029
negative regulation of cellular metabolic process GO:0031324 382 0.029
phosphorylation GO:0016310 294 0.029
spermatogenesis GO:0007283 200 0.029
neuroblast proliferation GO:0007405 74 0.029
morphogenesis of an epithelium GO:0002009 276 0.029
neuroblast division GO:0055057 35 0.029
positive regulation of signal transduction GO:0009967 223 0.029
asymmetric stem cell division GO:0098722 49 0.028
single organism catabolic process GO:0044712 228 0.028
organelle fission GO:0048285 340 0.028
response to abiotic stimulus GO:0009628 341 0.028
negative regulation of rna biosynthetic process GO:1902679 240 0.028
regulation of catabolic process GO:0009894 170 0.028
cellular amino acid metabolic process GO:0006520 61 0.027
kidney development GO:0001822 3 0.027
neuron projection guidance GO:0097485 241 0.027
protein complex assembly GO:0006461 200 0.027
intracellular signal transduction GO:0035556 300 0.027
positive regulation of rna biosynthetic process GO:1902680 266 0.027
response to bacterium GO:0009617 198 0.027
protein modification process GO:0036211 438 0.026
death GO:0016265 284 0.026
segmentation GO:0035282 207 0.026
defense response to other organism GO:0098542 225 0.026
nuclear division GO:0000280 332 0.025
single organism behavior GO:0044708 391 0.025
body morphogenesis GO:0010171 2 0.025
negative regulation of developmental process GO:0051093 201 0.025
spindle organization GO:0007051 253 0.025
regulation of cell death GO:0010941 173 0.025
negative regulation of cellular biosynthetic process GO:0031327 277 0.025
establishment of organelle localization GO:0051656 122 0.025
endocytosis GO:0006897 310 0.025
positive regulation of nitrogen compound metabolic process GO:0051173 354 0.025
regulation of cell cycle process GO:0010564 181 0.025
purine containing compound metabolic process GO:0072521 155 0.024
taxis GO:0042330 304 0.024
protein complex biogenesis GO:0070271 201 0.024
organelle assembly GO:0070925 198 0.024
antimicrobial humoral response GO:0019730 99 0.024
spindle assembly GO:0051225 80 0.024
negative regulation of nitrogen compound metabolic process GO:0051172 265 0.024
intracellular transport GO:0046907 228 0.023
cellular component assembly involved in morphogenesis GO:0010927 151 0.023
chaeta development GO:0022416 97 0.023
positive regulation of nucleobase containing compound metabolic process GO:0045935 332 0.023
chromatin organization GO:0006325 207 0.023
metal ion transport GO:0030001 74 0.023
negative regulation of biosynthetic process GO:0009890 277 0.023
regulation of transcription from rna polymerase ii promoter GO:0006357 378 0.023
cellular catabolic process GO:0044248 372 0.023
negative regulation of nucleobase containing compound metabolic process GO:0045934 261 0.023
chemotaxis GO:0006935 249 0.022
circulatory system development GO:0072359 82 0.022
regulation of programmed cell death GO:0043067 152 0.022
eye development GO:0001654 323 0.022
negative regulation of cellular macromolecule biosynthetic process GO:2000113 267 0.022
negative regulation of transcription dna templated GO:0045892 237 0.022
negative regulation of rna metabolic process GO:0051253 251 0.022
cellular protein modification process GO:0006464 438 0.022
neurological system process GO:0050877 358 0.022
cellular response to dna damage stimulus GO:0006974 223 0.022
regulation of nervous system development GO:0051960 248 0.021
phagocytosis GO:0006909 215 0.021
negative regulation of nucleic acid templated transcription GO:1903507 240 0.021
enzyme linked receptor protein signaling pathway GO:0007167 179 0.021
photoreceptor cell differentiation GO:0046530 170 0.021
developmental growth GO:0048589 280 0.021
establishment of planar polarity GO:0001736 87 0.021
oxoacid metabolic process GO:0043436 103 0.021
organic substance catabolic process GO:1901575 308 0.021
organophosphate metabolic process GO:0019637 195 0.021
cell cell signaling involved in cell fate commitment GO:0045168 210 0.021
appendage development GO:0048736 401 0.020
defense response to bacterium GO:0042742 178 0.020
regulation of cellular amine metabolic process GO:0033238 3 0.020
regulation of cellular catabolic process GO:0031329 157 0.020
immune system process GO:0002376 347 0.020
cardiovascular system development GO:0072358 82 0.020
compound eye morphogenesis GO:0001745 249 0.020
neural precursor cell proliferation GO:0061351 75 0.020
regulation of molecular function GO:0065009 217 0.020
meiotic cell cycle process GO:1903046 132 0.020
cellular macromolecule localization GO:0070727 220 0.020
regulation of cell cycle GO:0051726 291 0.019
regulation of cell cycle phase transition GO:1901987 130 0.019
spermatid development GO:0007286 98 0.019
regulation of cellular component biogenesis GO:0044087 201 0.019
regionalization GO:0003002 416 0.019
stem cell proliferation GO:0072089 88 0.019
sterol homeostasis GO:0055092 4 0.019
sensory organ morphogenesis GO:0090596 260 0.019
regulation of mitotic cell cycle GO:0007346 190 0.019
cellular response to chemical stimulus GO:0070887 199 0.019
ribonucleoside metabolic process GO:0009119 127 0.019
eye photoreceptor cell differentiation GO:0001754 145 0.019
neuronal stem cell division GO:0036445 35 0.019
cytokinesis GO:0000910 90 0.019
connective tissue development GO:0061448 3 0.018
imaginal disc derived wing morphogenesis GO:0007476 337 0.018
establishment of protein localization GO:0045184 163 0.018
eye morphogenesis GO:0048592 260 0.018
lateral inhibition GO:0046331 206 0.018
forebrain development GO:0030900 2 0.018
positive regulation of cellular biosynthetic process GO:0031328 316 0.018
regulation of cellular amino acid metabolic process GO:0006521 0 0.018
regulation of localization GO:0032879 275 0.018
purine nucleoside catabolic process GO:0006152 112 0.018
nucleoside phosphate metabolic process GO:0006753 162 0.018
axon guidance GO:0007411 233 0.018
axis specification GO:0009798 167 0.017
vesicle mediated transport GO:0016192 381 0.017
macromolecule catabolic process GO:0009057 161 0.017
positive regulation of macromolecule biosynthetic process GO:0010557 283 0.017
open tracheal system development GO:0007424 204 0.017
positive regulation of macromolecule metabolic process GO:0010604 405 0.017
appendage morphogenesis GO:0035107 397 0.017
ribonucleotide metabolic process GO:0009259 145 0.017
carbohydrate derivative metabolic process GO:1901135 217 0.017
cellular response to organic substance GO:0071310 132 0.017
programmed cell death GO:0012501 257 0.017
regulation of phosphorus metabolic process GO:0051174 210 0.017
purine nucleotide metabolic process GO:0006163 146 0.017
regulation of response to stress GO:0080134 200 0.017
nucleotide catabolic process GO:0009166 109 0.017
regulation of anatomical structure morphogenesis GO:0022603 242 0.016
nucleobase containing compound catabolic process GO:0034655 165 0.016
developmental programmed cell death GO:0010623 138 0.016
synaptic transmission GO:0007268 288 0.016
single organism biosynthetic process GO:0044711 206 0.016
regulation of cellular ketone metabolic process GO:0010565 3 0.016
macromolecular complex assembly GO:0065003 256 0.016
positive regulation of nucleic acid templated transcription GO:1903508 266 0.016
compound eye photoreceptor cell differentiation GO:0001751 140 0.016
rna splicing GO:0008380 83 0.016
wing disc morphogenesis GO:0007472 344 0.016
regulation of catalytic activity GO:0050790 185 0.016
photoreceptor cell development GO:0042461 96 0.016
homeostatic process GO:0042592 199 0.016
negative regulation of signaling GO:0023057 219 0.016
rna splicing via transesterification reactions GO:0000375 73 0.016
skin development GO:0043588 65 0.016
asymmetric neuroblast division GO:0055059 33 0.016
gene silencing GO:0016458 138 0.016
tube development GO:0035295 244 0.016
regulation of gene expression epigenetic GO:0040029 128 0.016
humoral immune response GO:0006959 117 0.016
mitotic spindle organization GO:0007052 220 0.016
compound eye development GO:0048749 307 0.016
eggshell formation GO:0030703 105 0.016
secretion GO:0046903 109 0.015
respiratory system development GO:0060541 213 0.015
regulation of immune system process GO:0002682 176 0.015
mushroom body development GO:0016319 70 0.015
response to lipopolysaccharide GO:0032496 4 0.015
stem cell division GO:0017145 69 0.015
nucleoside phosphate catabolic process GO:1901292 110 0.015
nucleoside metabolic process GO:0009116 127 0.015
positive regulation of phosphorus metabolic process GO:0010562 139 0.015
positive regulation of transcription dna templated GO:0045893 266 0.015
mrna splicing via spliceosome GO:0000398 73 0.015
proteolysis GO:0006508 192 0.015
single organism cellular localization GO:1902580 180 0.015
regulation of rna splicing GO:0043484 69 0.015
negative regulation of nervous system development GO:0051961 92 0.015
regulation of small gtpase mediated signal transduction GO:0051056 93 0.015
epithelial cell differentiation GO:0030855 322 0.015
meiotic cell cycle GO:0051321 171 0.015
response to oxygen containing compound GO:1901700 200 0.015
regulation of apoptotic process GO:0042981 130 0.015
eggshell chorion assembly GO:0007306 66 0.015
protein catabolic process GO:0030163 101 0.015
regulation of protein metabolic process GO:0051246 256 0.015
morphogenesis of a polarized epithelium GO:0001738 93 0.015
vitamin metabolic process GO:0006766 2 0.015
camera type eye development GO:0043010 4 0.015
secretion by cell GO:0032940 101 0.015
positive regulation of transcription from rna polymerase ii promoter GO:0045944 204 0.015
actin filament organization GO:0007015 126 0.015
locomotory behavior GO:0007626 176 0.015
regulation of cell proliferation GO:0042127 163 0.015
negative regulation of cell differentiation GO:0045596 143 0.015
ribose phosphate metabolic process GO:0019693 145 0.014
purine nucleoside metabolic process GO:0042278 127 0.014
glycosyl compound metabolic process GO:1901657 127 0.014
negative regulation of transcription from rna polymerase ii promoter GO:0000122 119 0.014
heterocycle catabolic process GO:0046700 166 0.014
cellular protein localization GO:0034613 160 0.014
blastoderm segmentation GO:0007350 159 0.014
male gamete generation GO:0048232 201 0.014
fat soluble vitamin biosynthetic process GO:0042362 1 0.014
cell cycle phase transition GO:0044770 140 0.014
imaginal disc derived appendage morphogenesis GO:0035114 395 0.014
acid secretion GO:0046717 1 0.014
embryonic pattern specification GO:0009880 174 0.014
fat soluble vitamin metabolic process GO:0006775 1 0.014
apoptotic process GO:0006915 159 0.014
aromatic compound catabolic process GO:0019439 166 0.014
columnar cuboidal epithelial cell development GO:0002066 249 0.014
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 116 0.014
purine ribonucleoside triphosphate catabolic process GO:0009207 108 0.014
cell adhesion GO:0007155 136 0.014
post embryonic appendage morphogenesis GO:0035120 385 0.014
organelle localization GO:0051640 148 0.014
dendrite development GO:0016358 204 0.014
wing disc pattern formation GO:0035222 66 0.014
defense response to gram negative bacterium GO:0050829 94 0.014
positive regulation of gene expression GO:0010628 290 0.014
regulation of mitotic cell cycle phase transition GO:1901990 130 0.014
axon development GO:0061564 297 0.014
negative regulation of programmed cell death GO:0043069 72 0.014
cell motility GO:0048870 251 0.014
ribonucleoside triphosphate catabolic process GO:0009203 108 0.014
imaginal disc pattern formation GO:0007447 91 0.014
small gtpase mediated signal transduction GO:0007264 88 0.014
regulation of transport GO:0051049 181 0.014
regulation of cellular protein metabolic process GO:0032268 243 0.014
positive regulation of biosynthetic process GO:0009891 316 0.014
telencephalon development GO:0021537 2 0.014
cellular amine metabolic process GO:0044106 12 0.014
erbb signaling pathway GO:0038127 58 0.014
response to heat GO:0009408 63 0.014
regulation of epithelial cell differentiation GO:0030856 4 0.013
mrna processing GO:0006397 104 0.013
organic acid metabolic process GO:0006082 103 0.013
mitotic cell cycle phase transition GO:0044772 138 0.013
single organism intracellular transport GO:1902582 207 0.013
ovarian follicle cell development GO:0030707 248 0.013
spinal cord development GO:0021510 1 0.013
regulation of phosphate metabolic process GO:0019220 210 0.013
anterior posterior axis specification embryo GO:0008595 103 0.013
meiotic nuclear division GO:0007126 151 0.013
carbohydrate metabolic process GO:0005975 82 0.013
negative regulation of cell proliferation GO:0008285 69 0.013
regulation of epithelial cell proliferation GO:0050678 4 0.013
chromosome organization GO:0051276 360 0.013
response to organophosphorus GO:0046683 2 0.013
amine metabolic process GO:0009308 12 0.013
cell migration GO:0016477 238 0.013
synapse assembly GO:0007416 143 0.013
central nervous system development GO:0007417 201 0.013
cell cycle checkpoint GO:0000075 95 0.013
chorion containing eggshell formation GO:0007304 105 0.013
salivary gland development GO:0007431 162 0.013
positive regulation of cell migration GO:0030335 2 0.013
purine ribonucleotide metabolic process GO:0009150 145 0.013
ras protein signal transduction GO:0007265 88 0.013
embryonic development via the syncytial blastoderm GO:0001700 148 0.013
regulation of ras protein signal transduction GO:0046578 93 0.013
guanosine containing compound metabolic process GO:1901068 74 0.013
epithelial cell development GO:0002064 274 0.013
ribonucleotide catabolic process GO:0009261 109 0.013
mesenchymal cell development GO:0014031 1 0.012
establishment of tissue polarity GO:0007164 87 0.012
epithelial tube morphogenesis GO:0060562 88 0.012
positive regulation of multicellular organismal process GO:0051240 143 0.012
axonogenesis GO:0007409 290 0.012
monocarboxylic acid transport GO:0015718 3 0.012
regulation of cell development GO:0060284 215 0.012
regulation of anatomical structure size GO:0090066 163 0.012
organic cyclic compound catabolic process GO:1901361 168 0.012
response to monosaccharide GO:0034284 4 0.012
mitotic nuclear division GO:0007067 213 0.012
localization of cell GO:0051674 257 0.012
adult behavior GO:0030534 137 0.012
dna conformation change GO:0071103 105 0.012
transmembrane transport GO:0055085 139 0.012
segment specification GO:0007379 33 0.012
eye photoreceptor cell development GO:0042462 81 0.012
immune response activating signal transduction GO:0002757 2 0.012
morphogenesis of a branching structure GO:0001763 45 0.012
negative regulation of cell cycle phase transition GO:1901988 103 0.012
nitrogen compound transport GO:0071705 85 0.012
heart development GO:0007507 82 0.012
tissue migration GO:0090130 155 0.012
regulation of synaptic transmission GO:0050804 69 0.012
dna damage checkpoint GO:0000077 78 0.012
purine containing compound catabolic process GO:0072523 112 0.012
wnt signaling pathway GO:0016055 98 0.012
epithelial cell migration GO:0010631 148 0.012
purine nucleotide catabolic process GO:0006195 109 0.012
columnar cuboidal epithelial cell differentiation GO:0002065 256 0.012
cellular nitrogen compound catabolic process GO:0044270 165 0.012
negative regulation of cell cycle process GO:0010948 109 0.012
autophagic cell death GO:0048102 83 0.011
mesenchymal cell differentiation GO:0048762 1 0.011
nucleotide metabolic process GO:0009117 161 0.011
organic substance transport GO:0071702 257 0.011
negative regulation of cellular component organization GO:0051129 108 0.011
head development GO:0060322 135 0.011
salivary gland morphogenesis GO:0007435 145 0.011
rna localization GO:0006403 115 0.011
innate immune response GO:0045087 144 0.011
nucleoside triphosphate catabolic process GO:0009143 108 0.011
purine ribonucleotide catabolic process GO:0009154 109 0.011
developmental maturation GO:0021700 172 0.011
immune response regulating signaling pathway GO:0002764 2 0.011
carbohydrate derivative catabolic process GO:1901136 118 0.011
membrane organization GO:0061024 112 0.011
mitotic dna integrity checkpoint GO:0044774 75 0.011
purine ribonucleoside catabolic process GO:0046130 112 0.011
intracellular protein transport GO:0006886 104 0.011
salivary gland histolysis GO:0035070 88 0.011
positive regulation of molecular function GO:0044093 136 0.011
ameboidal type cell migration GO:0001667 151 0.011
negative regulation of cellular protein metabolic process GO:0032269 85 0.011
organophosphate catabolic process GO:0046434 112 0.011
branching morphogenesis of an epithelial tube GO:0048754 45 0.011
signal transduction by phosphorylation GO:0023014 107 0.011
regulation of neurogenesis GO:0050767 158 0.011
establishment of cell polarity GO:0030010 40 0.011
cellular ketone metabolic process GO:0042180 24 0.011
embryonic axis specification GO:0000578 107 0.011
negative regulation of response to stimulus GO:0048585 258 0.011
hormone catabolic process GO:0042447 3 0.011
response to nitrogen compound GO:1901698 90 0.011
negative regulation of protein metabolic process GO:0051248 85 0.011
negative regulation of signal transduction GO:0009968 206 0.011
response to glucose GO:0009749 2 0.011
somatic stem cell division GO:0048103 37 0.011
protein maturation GO:0051604 71 0.011
organonitrogen compound catabolic process GO:1901565 128 0.011
negative regulation of cell death GO:0060548 81 0.011
regulation of cell division GO:0051302 72 0.011
chromosome segregation GO:0007059 157 0.011
regulation of mrna metabolic process GO:1903311 72 0.011
cellular macromolecular complex assembly GO:0034622 153 0.010
response to gravity GO:0009629 26 0.010
response to endogenous stimulus GO:0009719 119 0.010
dorsal ventral pattern formation GO:0009953 133 0.010
peptidyl amino acid modification GO:0018193 105 0.010
mitotic cell cycle checkpoint GO:0007093 88 0.010
gtp catabolic process GO:0006184 72 0.010
nucleoside catabolic process GO:0009164 112 0.010
response to hexose GO:0009746 3 0.010
nucleoside triphosphate metabolic process GO:0009141 120 0.010
defense response to fungus GO:0050832 48 0.010
regulation of organelle organization GO:0033043 196 0.010
gtp metabolic process GO:0046039 72 0.010
regulation of nucleotide metabolic process GO:0006140 62 0.010
neuron recognition GO:0008038 101 0.010
cellular response to carbohydrate stimulus GO:0071322 4 0.010
vitamin biosynthetic process GO:0009110 1 0.010
regulation of protein stability GO:0031647 43 0.010
positive regulation of cell motility GO:2000147 3 0.010
maintenance of location GO:0051235 73 0.010
negative regulation of multicellular organismal process GO:0051241 142 0.010
rna splicing via transesterification reactions with bulged adenosine as nucleophile GO:0000377 73 0.010
olfactory behavior GO:0042048 97 0.010
glycosyl compound catabolic process GO:1901658 112 0.010
somatic muscle development GO:0007525 66 0.010
stem cell differentiation GO:0048863 117 0.010
purine nucleoside triphosphate metabolic process GO:0009144 119 0.010
regulation of cell morphogenesis GO:0022604 163 0.010
gland morphogenesis GO:0022612 145 0.010
negative regulation of growth GO:0045926 84 0.010
regulation of cellular component size GO:0032535 98 0.010

CG42674 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.035
nervous system disease DOID:863 0 0.020
disease of metabolism DOID:0014667 0 0.017
inherited metabolic disorder DOID:655 0 0.015
cancer DOID:162 0 0.015
disease of cellular proliferation DOID:14566 0 0.015
musculoskeletal system disease DOID:17 0 0.013
sensory system disease DOID:0050155 0 0.012
eye and adnexa disease DOID:1492 0 0.012
acquired metabolic disease DOID:0060158 0 0.012
bone disease DOID:0080001 0 0.012
connective tissue disease DOID:65 0 0.012
cardiovascular system disease DOID:1287 0 0.011
organ system cancer DOID:0050686 0 0.011
urinary system disease DOID:18 0 0.011
eye disease DOID:5614 0 0.010