Drosophila melanogaster

37 known processes

Mdr49 (Dmel_CG3879)

Multi drug resistance 49

(Aliases: MDR5,mrd49,mdr49,Dmel\CG3879,Mes5,MDR49,CG3879,Dm5)

Mdr49 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
regionalization GO:0003002 416 0.079
secondary metabolic process GO:0019748 75 0.058
tube development GO:0035295 244 0.057
defense response GO:0006952 300 0.056
Worm
response to organic substance GO:0010033 284 0.054
organic acid metabolic process GO:0006082 103 0.054
immune response GO:0006955 246 0.050
Worm
response to other organism GO:0051707 293 0.049
Worm
defense response to bacterium GO:0042742 178 0.048
Worm
epithelial cell differentiation GO:0030855 322 0.046
Rat
cellular catabolic process GO:0044248 372 0.046
Yeast Fly
organonitrogen compound metabolic process GO:1901564 318 0.044
Yeast Fly
imaginal disc derived appendage development GO:0048737 399 0.044
positive regulation of response to stimulus GO:0048584 323 0.044
Rat
establishment of localization in cell GO:0051649 402 0.044
defense response to other organism GO:0098542 225 0.043
Worm
wing disc morphogenesis GO:0007472 344 0.043
dorsal ventral pattern formation GO:0009953 133 0.043
forebrain development GO:0030900 2 0.041
organic substance catabolic process GO:1901575 308 0.040
Yeast Fly
response to bacterium GO:0009617 198 0.040
Worm
columnar cuboidal epithelial cell development GO:0002066 249 0.040
carboxylic acid metabolic process GO:0019752 92 0.040
central nervous system development GO:0007417 201 0.039
Rat
positive regulation of signal transduction GO:0009967 223 0.038
lateral inhibition GO:0046331 206 0.037
oxoacid metabolic process GO:0043436 103 0.037
immune system process GO:0002376 347 0.036
Worm
dna metabolic process GO:0006259 227 0.036
nucleobase containing compound catabolic process GO:0034655 165 0.036
Yeast Fly
response to abiotic stimulus GO:0009628 341 0.036
response to external biotic stimulus GO:0043207 293 0.036
Worm
positive regulation of cell communication GO:0010647 250 0.036
organic substance transport GO:0071702 257 0.035
Yeast Rat
defense response to gram negative bacterium GO:0050829 94 0.034
Worm
nuclear division GO:0000280 332 0.033
axis specification GO:0009798 167 0.033
growth GO:0040007 359 0.033
catabolic process GO:0009056 409 0.033
Yeast Fly
single organism behavior GO:0044708 391 0.033
chromosome organization GO:0051276 360 0.032
tube morphogenesis GO:0035239 191 0.032
negative regulation of response to stimulus GO:0048585 258 0.032
cellular amino acid metabolic process GO:0006520 61 0.031
small molecule metabolic process GO:0044281 305 0.031
Yeast Fly
protein localization GO:0008104 284 0.031
regulation of intracellular signal transduction GO:1902531 236 0.030
single organism catabolic process GO:0044712 228 0.030
Yeast Fly
regulation of cell cycle GO:0051726 291 0.030
chromatin organization GO:0006325 207 0.030
epithelial cell development GO:0002064 274 0.029
Rat
chemotaxis GO:0006935 249 0.029
cell death GO:0008219 279 0.029
Rat
cellular protein modification process GO:0006464 438 0.029
vesicle mediated transport GO:0016192 381 0.028
imaginal disc derived wing morphogenesis GO:0007476 337 0.028
developmental maturation GO:0021700 172 0.028
pigment metabolic process GO:0042440 84 0.028
organic cyclic compound catabolic process GO:1901361 168 0.028
Yeast Fly
post embryonic appendage morphogenesis GO:0035120 385 0.028
developmental growth GO:0048589 280 0.027
ion transport GO:0006811 145 0.027
Rat
positive regulation of intracellular signal transduction GO:1902533 116 0.026
organelle fission GO:0048285 340 0.026
tissue morphogenesis GO:0048729 297 0.026
cell motility GO:0048870 251 0.026
endocytosis GO:0006897 310 0.025
intracellular signal transduction GO:0035556 300 0.025
cellular nitrogen compound catabolic process GO:0044270 165 0.025
Yeast Fly
programmed cell death GO:0012501 257 0.025
negative regulation of cellular metabolic process GO:0031324 382 0.025
negative regulation of rna biosynthetic process GO:1902679 240 0.025
steroid catabolic process GO:0006706 1 0.025
ovarian follicle cell development GO:0030707 248 0.025
regulation of response to stress GO:0080134 200 0.024
negative regulation of gene expression GO:0010629 387 0.024
meiotic nuclear division GO:0007126 151 0.024
embryo development ending in birth or egg hatching GO:0009792 152 0.024
Worm
nucleoside phosphate metabolic process GO:0006753 162 0.023
Yeast Fly
columnar cuboidal epithelial cell differentiation GO:0002065 256 0.023
organonitrogen compound catabolic process GO:1901565 128 0.023
Yeast Fly
aromatic compound catabolic process GO:0019439 166 0.023
Yeast Fly
macromolecular complex assembly GO:0065003 256 0.023
eggshell formation GO:0030703 105 0.023
intracellular transport GO:0046907 228 0.023
innate immune response GO:0045087 144 0.023
Worm
appendage development GO:0048736 401 0.023
dendrite morphogenesis GO:0048813 199 0.022
regulation of multicellular organismal development GO:2000026 414 0.022
neurological system process GO:0050877 358 0.022
digestive tract development GO:0048565 149 0.022
purine containing compound metabolic process GO:0072521 155 0.021
Yeast Fly
cellular protein localization GO:0034613 160 0.021
polyol biosynthetic process GO:0046173 3 0.021
death GO:0016265 284 0.021
Rat
cellular response to chemical stimulus GO:0070887 199 0.021
Rat
xenobiotic catabolic process GO:0042178 1 0.021
organophosphate metabolic process GO:0019637 195 0.021
Yeast Fly
cellular macromolecule localization GO:0070727 220 0.021
transcription from rna polymerase ii promoter GO:0006366 368 0.021
response to monosaccharide GO:0034284 4 0.021
embryonic pattern specification GO:0009880 174 0.021
carbohydrate derivative metabolic process GO:1901135 217 0.021
Yeast Fly
cellular response to organic substance GO:0071310 132 0.021
Rat
negative regulation of cellular biosynthetic process GO:0031327 277 0.021
digestive tract morphogenesis GO:0048546 127 0.021
posttranscriptional regulation of gene expression GO:0010608 145 0.021
negative regulation of cellular component organization GO:0051129 108 0.020
localization of cell GO:0051674 257 0.020
body morphogenesis GO:0010171 2 0.020
positive regulation of signaling GO:0023056 243 0.020
phagocytosis GO:0006909 215 0.020
positive regulation of nitrogen compound metabolic process GO:0051173 354 0.020
cellular macromolecule catabolic process GO:0044265 136 0.020
rhythmic process GO:0048511 106 0.020
Rat
imaginal disc derived appendage morphogenesis GO:0035114 395 0.020
appendage morphogenesis GO:0035107 397 0.020
epithelium migration GO:0090132 148 0.019
regulation of protein metabolic process GO:0051246 256 0.019
cellular response to dna damage stimulus GO:0006974 223 0.019
telencephalon development GO:0021537 2 0.019
dorsal appendage formation GO:0046843 47 0.019
single organism intracellular transport GO:1902582 207 0.019
negative regulation of cellular protein metabolic process GO:0032269 85 0.018
organelle localization GO:0051640 148 0.018
anion transport GO:0006820 41 0.018
response to biotic stimulus GO:0009607 294 0.018
Worm
rna processing GO:0006396 147 0.018
dorsal ventral axis specification GO:0009950 66 0.018
taxis GO:0042330 304 0.018
actin filament based process GO:0030029 220 0.018
response to glucose GO:0009749 2 0.018
response to organophosphorus GO:0046683 2 0.018
chaeta development GO:0022416 97 0.018
axonogenesis GO:0007409 290 0.018
mrna processing GO:0006397 104 0.018
sensory perception of chemical stimulus GO:0007606 116 0.018
protein maturation GO:0051604 71 0.018
germ cell migration GO:0008354 43 0.017
macromolecule catabolic process GO:0009057 161 0.017
monocarboxylic acid transport GO:0015718 3 0.017
dendrite development GO:0016358 204 0.017
camera type eye development GO:0043010 4 0.017
positive regulation of nucleobase containing compound metabolic process GO:0045935 332 0.017
nucleotide metabolic process GO:0009117 161 0.017
Yeast Fly
protein modification process GO:0036211 438 0.017
cellularization GO:0007349 90 0.017
regulation of cellular protein metabolic process GO:0032268 243 0.017
purine nucleoside catabolic process GO:0006152 112 0.017
Yeast Fly
open tracheal system development GO:0007424 204 0.017
purine nucleoside metabolic process GO:0042278 127 0.017
Yeast Fly
cell maturation GO:0048469 144 0.017
wing disc pattern formation GO:0035222 66 0.017
cell migration GO:0016477 238 0.017
ribose phosphate metabolic process GO:0019693 145 0.016
Yeast Fly
translation GO:0006412 69 0.016
kidney development GO:0001822 3 0.016
homeostatic process GO:0042592 199 0.016
negative regulation of cellular macromolecule biosynthetic process GO:2000113 267 0.016
muscle organ development GO:0007517 127 0.016
response to lipopolysaccharide GO:0032496 4 0.016
protein complex biogenesis GO:0070271 201 0.016
oligosaccharide transport GO:0015772 2 0.016
pole plasm assembly GO:0007315 61 0.016
morphogenesis of an epithelium GO:0002009 276 0.016
molting cycle chitin based cuticle GO:0007591 56 0.016
imaginal disc pattern formation GO:0007447 91 0.016
negative regulation of nucleobase containing compound metabolic process GO:0045934 261 0.016
carbohydrate metabolic process GO:0005975 82 0.016
developmental programmed cell death GO:0010623 138 0.016
nucleoside phosphate catabolic process GO:1901292 110 0.016
Yeast Fly
rna localization GO:0006403 115 0.015
purine ribonucleoside metabolic process GO:0046128 127 0.015
Yeast Fly
regulation of transcription from rna polymerase ii promoter GO:0006357 378 0.015
exocrine system development GO:0035272 162 0.015
cellular component assembly involved in morphogenesis GO:0010927 151 0.015
cellular homeostasis GO:0019725 80 0.015
embryonic morphogenesis GO:0048598 206 0.015
transmembrane transport GO:0055085 139 0.015
Human Yeast Rat Fly
protein processing GO:0016485 68 0.015
chorion containing eggshell formation GO:0007304 105 0.015
wound healing GO:0042060 75 0.015
purine ribonucleotide metabolic process GO:0009150 145 0.015
Yeast Fly
humoral immune response GO:0006959 117 0.015
response to temperature stimulus GO:0009266 106 0.015
autophagy GO:0006914 108 0.015
embryonic development via the syncytial blastoderm GO:0001700 148 0.015
sensory perception of smell GO:0007608 80 0.015
single organism biosynthetic process GO:0044711 206 0.015
meiosis i GO:0007127 59 0.015
actin cytoskeleton organization GO:0030036 206 0.015
ribonucleoside triphosphate metabolic process GO:0009199 119 0.015
Yeast Fly
cellular ketone metabolic process GO:0042180 24 0.015
heterocycle catabolic process GO:0046700 166 0.015
Yeast Fly
negative regulation of cell differentiation GO:0045596 143 0.015
eggshell chorion assembly GO:0007306 66 0.015
small gtpase mediated signal transduction GO:0007264 88 0.015
meiotic cell cycle GO:0051321 171 0.015
segmentation GO:0035282 207 0.014
connective tissue development GO:0061448 3 0.014
ras protein signal transduction GO:0007265 88 0.014
response to hexose GO:0009746 3 0.014
cellular macromolecular complex assembly GO:0034622 153 0.014
ribonucleotide metabolic process GO:0009259 145 0.014
Yeast Fly
regulation of cellular ketone metabolic process GO:0010565 3 0.014
proteolysis GO:0006508 192 0.014
ameboidal type cell migration GO:0001667 151 0.014
positive regulation of gene expression GO:0010628 290 0.014
regulation of phosphate metabolic process GO:0019220 210 0.014
regulation of mitotic cell cycle GO:0007346 190 0.014
mrna metabolic process GO:0016071 124 0.014
regulation of molecular function GO:0065009 217 0.014
enzyme linked receptor protein signaling pathway GO:0007167 179 0.014
establishment of protein localization GO:0045184 163 0.014
regulation of mitotic cell cycle phase transition GO:1901990 130 0.014
regulation of localization GO:0032879 275 0.014
nucleobase containing small molecule metabolic process GO:0055086 174 0.014
Yeast Fly
regulation of transport GO:0051049 181 0.014
neuron projection guidance GO:0097485 241 0.014
protein complex assembly GO:0006461 200 0.014
protein transport GO:0015031 155 0.014
antimicrobial humoral response GO:0019730 99 0.014
pyridine containing compound metabolic process GO:0072524 3 0.014
sodium dependent phosphate transport GO:0044341 2 0.014
organic hydroxy compound metabolic process GO:1901615 83 0.014
negative regulation of macromolecule biosynthetic process GO:0010558 270 0.014
actin filament organization GO:0007015 126 0.014
regulation of cell differentiation GO:0045595 302 0.014
sensory perception GO:0007600 196 0.014
nucleoside triphosphate catabolic process GO:0009143 108 0.014
Yeast Fly
response to radiation GO:0009314 155 0.014
Rat
anion homeostasis GO:0055081 3 0.014
regulation of organelle organization GO:0033043 196 0.013
response to wounding GO:0009611 94 0.013
wnt signaling pathway GO:0016055 98 0.013
chromatin modification GO:0016568 147 0.013
nucleotide catabolic process GO:0009166 109 0.013
Yeast Fly
locomotory behavior GO:0007626 176 0.013
nucleoside catabolic process GO:0009164 112 0.013
Yeast Fly
positive regulation of rna metabolic process GO:0051254 271 0.013
negative regulation of signal transduction GO:0009968 206 0.013
cytoplasmic transport GO:0016482 130 0.013
oocyte development GO:0048599 124 0.013
jak stat cascade GO:0007259 49 0.013
negative regulation of protein metabolic process GO:0051248 85 0.013
oxidation reduction process GO:0055114 123 0.013
positive regulation of cellular catabolic process GO:0031331 95 0.013
negative regulation of cell communication GO:0010648 223 0.013
regulation of proteolysis GO:0030162 87 0.013
tripartite regional subdivision GO:0007351 103 0.013
digestive system development GO:0055123 149 0.013
purine nucleotide metabolic process GO:0006163 146 0.013
Yeast Fly
glycosyl compound metabolic process GO:1901657 127 0.013
Yeast Fly
purine nucleotide catabolic process GO:0006195 109 0.013
Yeast Fly
response to lipid GO:0033993 38 0.013
Rat
regulation of cellular localization GO:0060341 136 0.013
response to alcohol GO:0097305 95 0.013
Rat
l glutamate import GO:0051938 1 0.013
organophosphate catabolic process GO:0046434 112 0.013
Yeast Fly
positive regulation of cellular biosynthetic process GO:0031328 316 0.013
meiotic cell cycle process GO:1903046 132 0.013
photoreceptor cell differentiation GO:0046530 170 0.013
notch signaling pathway GO:0007219 120 0.013
mitotic cell cycle checkpoint GO:0007093 88 0.013
axon guidance GO:0007411 233 0.013
cell cell signaling involved in cell fate commitment GO:0045168 210 0.013
regulation of translation GO:0006417 56 0.013
oocyte construction GO:0007308 112 0.013
ribonucleotide catabolic process GO:0009261 109 0.013
Yeast Fly
regulation of notch signaling pathway GO:0008593 100 0.013
ribonucleoside triphosphate catabolic process GO:0009203 108 0.013
Yeast Fly
regulation of cellular amine metabolic process GO:0033238 3 0.013
purine nucleoside triphosphate catabolic process GO:0009146 108 0.013
Yeast Fly
nucleoside metabolic process GO:0009116 127 0.013
Yeast Fly
aggressive behavior GO:0002118 63 0.012
oocyte dorsal ventral axis specification GO:0007310 34 0.012
cell proliferation GO:0008283 299 0.012
Human
positive regulation of phosphate metabolic process GO:0045937 139 0.012
regulation of catabolic process GO:0009894 170 0.012
negative regulation of cell cycle phase transition GO:1901988 103 0.012
salivary gland morphogenesis GO:0007435 145 0.012
oocyte axis specification GO:0007309 108 0.012
limb morphogenesis GO:0035108 1 0.012
nucleoside triphosphate metabolic process GO:0009141 120 0.012
Yeast Fly
muscle structure development GO:0061061 224 0.012
ribonucleoside metabolic process GO:0009119 127 0.012
Yeast Fly
vitamin metabolic process GO:0006766 2 0.012
reproductive system development GO:0061458 74 0.012
Rat
male meiosis GO:0007140 52 0.012
blastoderm segmentation GO:0007350 159 0.012
disaccharide transport GO:0015766 2 0.012
secondary metabolite catabolic process GO:0090487 1 0.012
regulation of immune system process GO:0002682 176 0.012
regulation of cell cycle process GO:0010564 181 0.012
pigmentation GO:0043473 75 0.012
proteolysis involved in cellular protein catabolic process GO:0051603 83 0.012
hindbrain development GO:0030902 2 0.012
sex differentiation GO:0007548 81 0.012
regulation of cellular amino acid metabolic process GO:0006521 0 0.012
carbohydrate derivative catabolic process GO:1901136 118 0.012
Yeast Fly
chromatin remodeling GO:0006338 72 0.012
regulation of anatomical structure size GO:0090066 163 0.012
positive regulation of macromolecule metabolic process GO:0010604 405 0.012
purine containing compound catabolic process GO:0072523 112 0.012
Yeast Fly
pigment metabolic process involved in developmental pigmentation GO:0043324 33 0.012
positive regulation of i kappab kinase nf kappab signaling GO:0043123 1 0.012
cellular response to molecule of bacterial origin GO:0071219 3 0.012
response to decreased oxygen levels GO:0036293 58 0.012
l amino acid import GO:0043092 2 0.011
secretion GO:0046903 109 0.011
Rat
purine ribonucleoside triphosphate metabolic process GO:0009205 119 0.011
Yeast Fly
oxidoreduction coenzyme metabolic process GO:0006733 2 0.011
regulation of ras protein signal transduction GO:0046578 93 0.011
oocyte anterior posterior axis specification GO:0007314 72 0.011
mitochondrion organization GO:0007005 65 0.011
activation of innate immune response GO:0002218 4 0.011
protein catabolic process GO:0030163 101 0.011
cellular response to hexose stimulus GO:0071331 1 0.011
regulation of defense response GO:0031347 102 0.011
pole plasm rna localization GO:0007316 52 0.011
chemical homeostasis GO:0048878 92 0.011
regulation of immune response GO:0050776 118 0.011
chromosome segregation GO:0007059 157 0.011
oocyte differentiation GO:0009994 145 0.011
single organism carbohydrate metabolic process GO:0044723 72 0.011
lipid metabolic process GO:0006629 121 0.011
maternal determination of anterior posterior axis embryo GO:0008358 74 0.011
phosphorylation GO:0016310 294 0.011
tissue death GO:0016271 102 0.011
positive regulation of cell migration GO:0030335 2 0.011
response to hypoxia GO:0001666 53 0.011
nitrogen compound transport GO:0071705 85 0.011
Yeast Rat
mitotic nuclear division GO:0007067 213 0.011
negative regulation of nitrogen compound metabolic process GO:0051172 265 0.011
regulation of cellular catabolic process GO:0031329 157 0.011
negative regulation of transcription dna templated GO:0045892 237 0.011
response to oxygen levels GO:0070482 59 0.011
response to organonitrogen compound GO:0010243 75 0.011
establishment of organelle localization GO:0051656 122 0.011
regulation of cellular component biogenesis GO:0044087 201 0.011
regulation of innate immune response GO:0045088 71 0.011
regulation of developmental growth GO:0048638 174 0.011
negative regulation of mitotic cell cycle phase transition GO:1901991 103 0.011
response to mercury ion GO:0046689 3 0.011
positive regulation of catabolic process GO:0009896 105 0.011
wing disc dorsal ventral pattern formation GO:0048190 47 0.011
adult behavior GO:0030534 137 0.011
regulation of mrna metabolic process GO:1903311 72 0.011
phosphate ion transport GO:0006817 4 0.011
camera type eye morphogenesis GO:0048593 2 0.011
positive regulation of biosynthetic process GO:0009891 316 0.011
peptide biosynthetic process GO:0043043 42 0.011
amine metabolic process GO:0009308 12 0.011
cellular response to carbohydrate stimulus GO:0071322 4 0.011
tissue migration GO:0090130 155 0.010
purine ribonucleoside catabolic process GO:0046130 112 0.010
Yeast Fly
purine ribonucleotide catabolic process GO:0009154 109 0.010
Yeast Fly
negative regulation of developmental process GO:0051093 201 0.010
anterior posterior axis specification embryo GO:0008595 103 0.010
antibacterial humoral response GO:0019731 44 0.010
hematopoietic progenitor cell differentiation GO:0002244 1 0.010
ion transmembrane transport GO:0034220 122 0.010
secretion by cell GO:0032940 101 0.010
developmental pigmentation GO:0048066 68 0.010
amide biosynthetic process GO:0043604 42 0.010
response to copper ion GO:0046688 4 0.010
regulation of multi organism process GO:0043900 131 0.010
pole cell development GO:0007277 26 0.010
regulation of protein localization GO:0032880 76 0.010
mitotic cell cycle phase transition GO:0044772 138 0.010
Human
response to organic cyclic compound GO:0014070 89 0.010
response to nutrient levels GO:0031667 114 0.010
Rat
autophagic cell death GO:0048102 83 0.010
developmental growth involved in morphogenesis GO:0060560 65 0.010
glycosyl compound catabolic process GO:1901658 112 0.010
Yeast Fly
regulation of phosphorus metabolic process GO:0051174 210 0.010
positive regulation of cell motility GO:2000147 3 0.010
regulation of mrna processing GO:0050684 71 0.010
dorsal ventral pattern formation imaginal disc GO:0007450 51 0.010

Mdr49 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.045
Human
disease of metabolism DOID:0014667 0 0.016
inherited metabolic disorder DOID:655 0 0.014
nervous system disease DOID:863 0 0.013
hypertension DOID:10763 0 0.012
artery disease DOID:0050828 0 0.012
vascular disease DOID:178 0 0.012
cardiovascular system disease DOID:1287 0 0.012
cancer DOID:162 0 0.011
disease of cellular proliferation DOID:14566 0 0.011
organ system cancer DOID:0050686 0 0.011
urinary system disease DOID:18 0 0.010