Drosophila melanogaster

97 known processes

BEAF-32 (Dmel_CG10159)

Boundary element-associated factor of 32kD

(Aliases: bs04c01.y1,CG10159,Dmel\CG10159,BEAF32,beaf,Beaf-32,BEAF-32A,BEAF,BEAF-32B,BEAF32A,BEAF32B)

BEAF-32 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
negative regulation of cellular metabolic process GO:0031324 382 0.995
negative regulation of nucleobase containing compound metabolic process GO:0045934 261 0.994
negative regulation of response to stimulus GO:0048585 258 0.973
dna metabolic process GO:0006259 227 0.944
negative regulation of nitrogen compound metabolic process GO:0051172 265 0.927
negative regulation of transcription dna templated GO:0045892 237 0.926
negative regulation of cellular biosynthetic process GO:0031327 277 0.922
negative regulation of gene expression GO:0010629 387 0.915
negative regulation of gene expression epigenetic GO:0045814 77 0.912
chromatin silencing GO:0006342 76 0.901
chromatin modification GO:0016568 147 0.871
heterochromatin organization GO:0070828 25 0.847
negative regulation of rna metabolic process GO:0051253 251 0.845
negative regulation of biosynthetic process GO:0009890 277 0.821
programmed cell death GO:0012501 257 0.802
negative regulation of rna biosynthetic process GO:1902679 240 0.797
protein modification process GO:0036211 438 0.781
positive regulation of biosynthetic process GO:0009891 316 0.772
negative regulation of macromolecule biosynthetic process GO:0010558 270 0.756
chromatin organization GO:0006325 207 0.751
meiotic cell cycle GO:0051321 171 0.725
positive regulation of nitrogen compound metabolic process GO:0051173 354 0.649
meiotic cell cycle process GO:1903046 132 0.638
transcription from rna polymerase ii promoter GO:0006366 368 0.630
positive regulation of macromolecule metabolic process GO:0010604 405 0.593
regulation of cell cycle GO:0051726 291 0.589
regulation of heterochromatin assembly GO:0031445 8 0.588
neuron projection guidance GO:0097485 241 0.586
negative regulation of nucleic acid templated transcription GO:1903507 240 0.584
nuclear division GO:0000280 332 0.575
regulation of chromatin silencing GO:0031935 36 0.546
chromosome organization GO:0051276 360 0.542
negative regulation of cellular macromolecule biosynthetic process GO:2000113 267 0.540
organelle fission GO:0048285 340 0.535
positive regulation of response to stimulus GO:0048584 323 0.502
regulation of dna metabolic process GO:0051052 34 0.466
death GO:0016265 284 0.438
chromatin remodeling GO:0006338 72 0.415
regulation of catabolic process GO:0009894 170 0.410
peptidyl lysine trimethylation GO:0018023 6 0.398
regulation of transcription from rna polymerase ii promoter GO:0006357 378 0.387
positive regulation of nucleobase containing compound metabolic process GO:0045935 332 0.359
intermediate filament based process GO:0045103 1 0.335
regulation of cellular protein metabolic process GO:0032268 243 0.332
growth GO:0040007 359 0.329
regulation of cell cycle process GO:0010564 181 0.321
establishment of localization in cell GO:0051649 402 0.314
macromolecular complex assembly GO:0065003 256 0.299
regulation of gene expression epigenetic GO:0040029 128 0.295
regulation of cell death GO:0010941 173 0.284
mitotic dna integrity checkpoint GO:0044774 75 0.278
reproductive system development GO:0061458 74 0.265
negative regulation of cell communication GO:0010648 223 0.256
peptidyl lysine methylation GO:0018022 16 0.254
imaginal disc derived appendage development GO:0048737 399 0.254
regulation of growth GO:0040008 233 0.254
phosphorylation GO:0016310 294 0.253
ovarian follicle cell development GO:0030707 248 0.251
regulation of protein metabolic process GO:0051246 256 0.251
axon guidance GO:0007411 233 0.247
negative regulation of signaling GO:0023057 219 0.240
meiotic nuclear division GO:0007126 151 0.235
catabolic process GO:0009056 409 0.235
positive regulation of rna metabolic process GO:0051254 271 0.229
organophosphate metabolic process GO:0019637 195 0.226
regulation of developmental growth GO:0048638 174 0.214
axonogenesis GO:0007409 290 0.211
macromolecule catabolic process GO:0009057 161 0.211
gonad development GO:0008406 50 0.203
cognition GO:0050890 141 0.202
dna conformation change GO:0071103 105 0.201
negative regulation of signal transduction GO:0009968 206 0.195
regulation of cellular component biogenesis GO:0044087 201 0.190
mitotic g2 m transition checkpoint GO:0044818 70 0.185
multicellular organismal reproductive behavior GO:0033057 110 0.175
developmental growth GO:0048589 280 0.172
positive regulation of rna biosynthetic process GO:1902680 266 0.157
epithelial cell development GO:0002064 274 0.157
dna replication GO:0006260 48 0.153
taxis GO:0042330 304 0.150
negative regulation of cell cycle GO:0045786 116 0.142
compound eye development GO:0048749 307 0.141
development of primary sexual characteristics GO:0045137 50 0.136
mitotic g2 dna damage checkpoint GO:0007095 69 0.132
mitotic dna damage checkpoint GO:0044773 74 0.128
positive regulation of transcription dna templated GO:0045893 266 0.125
sister chromatid segregation GO:0000819 92 0.121
cellular response to dna damage stimulus GO:0006974 223 0.121
meiosis i GO:0007127 59 0.119
regulation of multicellular organismal development GO:2000026 414 0.119
positive regulation of cellular biosynthetic process GO:0031328 316 0.118
appendage development GO:0048736 401 0.113
cellular catabolic process GO:0044248 372 0.110
larval development GO:0002164 104 0.109
chromosome segregation GO:0007059 157 0.108
protein complex biogenesis GO:0070271 201 0.106
regulation of cell differentiation GO:0045595 302 0.105
reproductive structure development GO:0048608 74 0.101
positive regulation of gene expression GO:0010628 290 0.095
response to other organism GO:0051707 293 0.095
cellular ketone metabolic process GO:0042180 24 0.085
protein phosphorylation GO:0006468 169 0.084
gene silencing GO:0016458 138 0.084
negative regulation of neurogenesis GO:0050768 53 0.081
negative regulation of cell cycle process GO:0010948 109 0.081
dna packaging GO:0006323 91 0.075
appendage morphogenesis GO:0035107 397 0.070
eye development GO:0001654 323 0.068
aging GO:0007568 143 0.068
sensory organ morphogenesis GO:0090596 260 0.067
regulation of macroautophagy GO:0016241 15 0.066
apoptotic process GO:0006915 159 0.066
positive regulation of cell communication GO:0010647 250 0.066
negative regulation of developmental process GO:0051093 201 0.065
determination of adult lifespan GO:0008340 137 0.064
meiotic chromosome segregation GO:0045132 59 0.064
positive regulation of transcription from rna polymerase ii promoter GO:0045944 204 0.063
negative regulation of mitotic anaphase promoting complex activity GO:0060564 2 0.061
cellular protein modification process GO:0006464 438 0.060
positive regulation of macromolecule biosynthetic process GO:0010557 283 0.060
regulation of mitotic cell cycle GO:0007346 190 0.060
regulation of chromatin assembly GO:0010847 9 0.059
chromosome condensation GO:0030261 41 0.059
female meiotic division GO:0007143 70 0.058
regulation of phosphatase activity GO:0010921 3 0.058
heterochromatin assembly GO:0031507 13 0.055
regulation of multicellular organism growth GO:0040014 40 0.055
reproductive behavior GO:0019098 122 0.053
sex differentiation GO:0007548 81 0.053
imaginal disc derived wing morphogenesis GO:0007476 337 0.052
rna processing GO:0006396 147 0.051
positive regulation of protein metabolic process GO:0051247 128 0.050
histone h4 k20 methylation GO:0034770 4 0.050
aromatic compound catabolic process GO:0019439 166 0.050
positive regulation of nucleic acid templated transcription GO:1903508 266 0.049
telomere maintenance GO:0000723 21 0.049
dna alkylation GO:0006305 4 0.049
histone modification GO:0016570 106 0.048
macroautophagy GO:0016236 42 0.047
organic cyclic compound catabolic process GO:1901361 168 0.047
positive regulation of heterochromatin assembly GO:0031453 5 0.046
organic substance catabolic process GO:1901575 308 0.046
epithelial cell differentiation GO:0030855 322 0.046
actin filament based process GO:0030029 220 0.046
multicellular organism growth GO:0035264 46 0.044
spindle organization GO:0007051 253 0.044
dorsal closure leading edge cell differentiation GO:0046663 2 0.043
regulation of organ morphogenesis GO:2000027 78 0.041
regulation of transcription by chromatin organization GO:0034401 3 0.039
positive regulation of cellular amine metabolic process GO:0033240 0 0.039
cellular macromolecule catabolic process GO:0044265 136 0.038
regulation of programmed cell death GO:0043067 152 0.037
intracellular signal transduction GO:0035556 300 0.037
columnar cuboidal epithelial cell development GO:0002066 249 0.037
dna hypermethylation GO:0044026 3 0.035
wing disc morphogenesis GO:0007472 344 0.034
peptidyl amino acid modification GO:0018193 105 0.034
negative regulation of meiotic cell cycle GO:0051447 2 0.034
mitotic cell cycle phase transition GO:0044772 138 0.034
positive regulation of cellular catabolic process GO:0031331 95 0.034
axon development GO:0061564 297 0.034
regulation of response to stress GO:0080134 200 0.033
dna methylation or demethylation GO:0044728 4 0.033
actin cytoskeleton organization GO:0030036 206 0.033
regulation of response to extracellular stimulus GO:0032104 18 0.032
negative regulation of protein metabolic process GO:0051248 85 0.032
compound eye morphogenesis GO:0001745 249 0.032
positive regulation of signaling GO:0023056 243 0.032
cell proliferation GO:0008283 299 0.032
regulation of gene silencing GO:0060968 63 0.032
regulation of anatomical structure size GO:0090066 163 0.031
protein localization GO:0008104 284 0.030
positive regulation of developmental process GO:0051094 143 0.030
organonitrogen compound metabolic process GO:1901564 318 0.030
nucleobase containing compound catabolic process GO:0034655 165 0.029
multi organism reproductive behavior GO:0044705 121 0.029
negative regulation of transcription from rna polymerase ii promoter GO:0000122 119 0.028
intermediate filament cytoskeleton organization GO:0045104 1 0.028
cell cycle phase transition GO:0044770 140 0.027
multi organism behavior GO:0051705 175 0.027
chemotaxis GO:0006935 249 0.026
oocyte differentiation GO:0009994 145 0.026
immune system development GO:0002520 57 0.026
innate immune response GO:0045087 144 0.026
heterocycle catabolic process GO:0046700 166 0.026
mrna metabolic process GO:0016071 124 0.026
dna integrity checkpoint GO:0031570 81 0.025
cellular macromolecular complex assembly GO:0034622 153 0.025
regulation of molecular function GO:0065009 217 0.025
protein complex assembly GO:0006461 200 0.025
negative regulation of cell differentiation GO:0045596 143 0.025
mitochondrial membrane organization GO:0007006 3 0.024
embryo development ending in birth or egg hatching GO:0009792 152 0.024
regulation of protein modification process GO:0031399 112 0.024
cell proliferation involved in compound eye morphogenesis GO:0035736 4 0.024
regulation of cellular response to stress GO:0080135 89 0.023
mrna processing GO:0006397 104 0.023
negative regulation of multicellular organismal process GO:0051241 142 0.023
regulation of neurogenesis GO:0050767 158 0.022
eggshell formation GO:0030703 105 0.022
protein dna complex subunit organization GO:0071824 86 0.022
regulation of cellular amino acid metabolic process GO:0006521 0 0.021
negative regulation of cellular component organization GO:0051129 108 0.021
oocyte morphogenesis GO:0048601 3 0.021
post embryonic appendage morphogenesis GO:0035120 385 0.021
positive regulation of gene expression epigenetic GO:0045815 16 0.021
dorsal vessel heart proper cell fate commitment GO:0035053 2 0.020
protein alkylation GO:0008213 43 0.020
columnar cuboidal epithelial cell differentiation GO:0002065 256 0.020
histone lysine methylation GO:0034968 32 0.020
peptidyl lysine modification GO:0018205 57 0.020
regulation of apoptotic process GO:0042981 130 0.020
regulation of centriole replication GO:0046599 2 0.019
spermatogenesis GO:0007283 200 0.019
positive regulation of neuron projection regeneration GO:0070572 3 0.019
left right axis specification GO:0070986 1 0.019
regulation of phosphate metabolic process GO:0019220 210 0.019
maternal determination of dorsal ventral axis ovarian follicular epithelium soma encoded GO:0008071 1 0.019
compound eye photoreceptor cell differentiation GO:0001751 140 0.018
negative regulation of terminal cell fate specification open tracheal system GO:0035155 2 0.018
response to bacterium GO:0009617 198 0.018
positive regulation of multicellular organismal process GO:0051240 143 0.018
mitotic cell cycle checkpoint GO:0007093 88 0.018
body morphogenesis GO:0010171 2 0.018
mapk import into nucleus GO:0000189 1 0.018
nucleoside phosphate metabolic process GO:0006753 162 0.018
regulation of planar cell polarity pathway involved in axis elongation GO:2000040 2 0.018
positive regulation of signal transduction GO:0009967 223 0.017
nucleoside triphosphate metabolic process GO:0009141 120 0.017
g2 dna damage checkpoint GO:0031572 69 0.017
small molecule metabolic process GO:0044281 305 0.017
imaginal disc derived appendage morphogenesis GO:0035114 395 0.017
cell chemotaxis involved in malpighian tubule morphogenesis GO:0061352 3 0.017
negative regulation of cell cycle phase transition GO:1901988 103 0.017
oviposition GO:0018991 19 0.016
negative regulation of mitotic cell cycle GO:0045930 109 0.016
establishment or maintenance of cell polarity GO:0007163 167 0.016
positive regulation of cellular protein metabolic process GO:0032270 118 0.016
genitalia development GO:0048806 26 0.016
secretion by cell GO:0032940 101 0.016
cell death GO:0008219 279 0.016
neurological system process GO:0050877 358 0.016
dendrite regeneration GO:0031104 2 0.016
learning or memory GO:0007611 141 0.016
chromatin assembly GO:0031497 48 0.015
negative regulation of phosphatase activity GO:0010923 3 0.015
regulation of cellular amine metabolic process GO:0033238 3 0.015
chromatin assembly or disassembly GO:0006333 52 0.015
regulation of cell development GO:0060284 215 0.015
photoreceptor cell differentiation GO:0046530 170 0.015
negative regulation of mitotic cell cycle phase transition GO:1901991 103 0.015
ribose phosphate metabolic process GO:0019693 145 0.015
enzyme linked receptor protein signaling pathway GO:0007167 179 0.015
regulation of mitotic cell cycle phase transition GO:1901990 130 0.015
regulation of cell proliferation involved in compound eye morphogenesis GO:2000495 2 0.015
positive regulation of catabolic process GO:0009896 105 0.015
positive regulation of protein modification process GO:0031401 58 0.015
locomotory behavior GO:0007626 176 0.015
regulation of mrna metabolic process GO:1903311 72 0.015
purine ribonucleotide metabolic process GO:0009150 145 0.014
regulation of hemocyte proliferation GO:0035206 37 0.014
purine nucleotide metabolic process GO:0006163 146 0.014
positive regulation of molecular function GO:0044093 136 0.014
cellular nitrogen compound catabolic process GO:0044270 165 0.014
reactive oxygen species biosynthetic process GO:1903409 0 0.014
meiotic nuclear envelope disassembly GO:0051078 2 0.013
positive regulation of dna metabolic process GO:0051054 12 0.013
amine metabolic process GO:0009308 12 0.013
organic acid metabolic process GO:0006082 103 0.013
single organism biosynthetic process GO:0044711 206 0.013
regulation of intracellular signal transduction GO:1902531 236 0.013
border follicle cell delamination GO:0030709 3 0.013
chitin based larval cuticle pattern formation GO:0035293 11 0.013
homeostatic process GO:0042592 199 0.013
regulation of cellular component size GO:0032535 98 0.013
telomere organization GO:0032200 21 0.013
regulation of nervous system development GO:0051960 248 0.013
detection of virus GO:0009597 1 0.013
negative regulation of programmed cell death GO:0043069 72 0.013
regulation of ral protein signal transduction GO:0032485 1 0.012
regulation of cellular catabolic process GO:0031329 157 0.012
regulation of reactive oxygen species biosynthetic process GO:1903426 0 0.012
peptidyl lysine dimethylation GO:0018027 3 0.012
purine ribonucleoside metabolic process GO:0046128 127 0.012
positive regulation of catalytic activity GO:0043085 118 0.012
oocyte fate commitment GO:0048600 2 0.012
nucleotide metabolic process GO:0009117 161 0.012
single organism behavior GO:0044708 391 0.012
regulation of multivesicular body size GO:0010796 3 0.012
small gtpase mediated signal transduction GO:0007264 88 0.012
regulation of cellular ketone metabolic process GO:0010565 3 0.011
establishment or maintenance of polarity of larval imaginal disc epithelium GO:0016336 3 0.011
response to external biotic stimulus GO:0043207 293 0.011
anterior posterior axis specification follicular epithelium GO:0030714 2 0.011
anatomical structure homeostasis GO:0060249 97 0.011
specification of segmental identity antennal segment GO:0007383 2 0.011
anterior head segmentation GO:0035288 3 0.011
negative regulation of apoptotic process GO:0043066 63 0.011
mitotic nuclear division GO:0007067 213 0.011
regulation of hydrolase activity GO:0051336 97 0.011
reactive nitrogen species metabolic process GO:2001057 0 0.011
positive regulation of cell maturation GO:1903431 2 0.010
cellular response to extracellular stimulus GO:0031668 64 0.010
nucleosome organization GO:0034728 59 0.010
defense response GO:0006952 300 0.010
response to extracellular stimulus GO:0009991 116 0.010
exocrine system development GO:0035272 162 0.010
immune response GO:0006955 246 0.010

BEAF-32 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

Disease DO term ID Size Probability Func Analog Org
nervous system benign neoplasm DOID:0060115 0 0.017
organ system benign neoplasm DOID:0060085 0 0.017
neuroma DOID:2001 0 0.017
benign neoplasm DOID:0060072 0 0.017
disease of cellular proliferation DOID:14566 0 0.017
endocrine gland cancer DOID:170 0 0.016
thyroid cancer DOID:1781 0 0.016
cancer DOID:162 0 0.016
organ system cancer DOID:0050686 0 0.016
heart disease DOID:114 0 0.015
heart valve disease DOID:4079 0 0.015
disease of anatomical entity DOID:7 0 0.015
cardiovascular system disease DOID:1287 0 0.015
aortic valve disease DOID:62 0 0.015