Drosophila melanogaster

72 known processes

SP2353 (Dmel_CG8403)

CG8403 gene product from transcript CG8403-RA

(Aliases: CT18665,Dmel\CG8403,BcDNA:GH12319,CG8403)

SP2353 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
small molecule metabolic process GO:0044281 305 0.074
organonitrogen compound metabolic process GO:1901564 318 0.074
single organism behavior GO:0044708 391 0.073
phosphorylation GO:0016310 294 0.070
protein modification process GO:0036211 438 0.055
single organism biosynthetic process GO:0044711 206 0.052
cell cell adhesion via plasma membrane adhesion molecules GO:0098742 26 0.050
carbohydrate derivative metabolic process GO:1901135 217 0.047
carboxylic acid metabolic process GO:0019752 92 0.046
axonogenesis GO:0007409 290 0.046
organonitrogen compound biosynthetic process GO:1901566 117 0.046
tube development GO:0035295 244 0.045
organic acid metabolic process GO:0006082 103 0.045
response to organic substance GO:0010033 284 0.043
positive regulation of response to stimulus GO:0048584 323 0.043
positive regulation of cellular biosynthetic process GO:0031328 316 0.043
lateral inhibition GO:0046331 206 0.042
cell cell signaling involved in cell fate commitment GO:0045168 210 0.040
cellular protein modification process GO:0006464 438 0.040
respiratory system development GO:0060541 213 0.040
response to oxygen containing compound GO:1901700 200 0.039
regulation of phosphate metabolic process GO:0019220 210 0.039
mating GO:0007618 120 0.038
regulation of localization GO:0032879 275 0.038
organophosphate metabolic process GO:0019637 195 0.038
intracellular signal transduction GO:0035556 300 0.037
positive regulation of biosynthetic process GO:0009891 316 0.037
transcription from rna polymerase ii promoter GO:0006366 368 0.037
negative regulation of cellular metabolic process GO:0031324 382 0.036
positive regulation of nucleobase containing compound metabolic process GO:0045935 332 0.036
regulation of phosphorus metabolic process GO:0051174 210 0.036
g protein coupled receptor signaling pathway GO:0007186 136 0.036
vesicle mediated transport GO:0016192 381 0.035
regulation of molecular function GO:0065009 217 0.035
positive regulation of macromolecule metabolic process GO:0010604 405 0.035
oxoacid metabolic process GO:0043436 103 0.034
forebrain development GO:0030900 2 0.034
death GO:0016265 284 0.034
cellular ketone metabolic process GO:0042180 24 0.033
open tracheal system development GO:0007424 204 0.032
positive regulation of signaling GO:0023056 243 0.032
endocytosis GO:0006897 310 0.032
positive regulation of nitrogen compound metabolic process GO:0051173 354 0.032
purine containing compound metabolic process GO:0072521 155 0.031
positive regulation of signal transduction GO:0009967 223 0.031
appendage morphogenesis GO:0035107 397 0.031
programmed cell death GO:0012501 257 0.031
axon development GO:0061564 297 0.030
appendage development GO:0048736 401 0.030
negative regulation of cell communication GO:0010648 223 0.030
regulation of catalytic activity GO:0050790 185 0.030
regulation of phosphorylation GO:0042325 147 0.030
body morphogenesis GO:0010171 2 0.030
chemotaxis GO:0006935 249 0.029
cellular amino acid metabolic process GO:0006520 61 0.029
response to abiotic stimulus GO:0009628 341 0.029
neuron projection guidance GO:0097485 241 0.029
regulation of tube architecture open tracheal system GO:0035152 68 0.029
organelle fission GO:0048285 340 0.029
nucleobase containing small molecule metabolic process GO:0055086 174 0.029
positive regulation of phosphate metabolic process GO:0045937 139 0.029
negative regulation of response to stimulus GO:0048585 258 0.029
cell proliferation GO:0008283 299 0.029
homeostatic process GO:0042592 199 0.029
response to glucose GO:0009749 2 0.028
ribose phosphate metabolic process GO:0019693 145 0.028
neurological system process GO:0050877 358 0.028
catabolic process GO:0009056 409 0.028
nucleotide metabolic process GO:0009117 161 0.028
phagocytosis GO:0006909 215 0.028
neuromuscular junction development GO:0007528 149 0.027
purine nucleotide metabolic process GO:0006163 146 0.027
homophilic cell adhesion via plasma membrane adhesion molecules GO:0007156 18 0.027
carbohydrate derivative biosynthetic process GO:1901137 85 0.027
response to monosaccharide GO:0034284 4 0.027
negative regulation of nucleobase containing compound metabolic process GO:0045934 261 0.027
regulation of cell cycle GO:0051726 291 0.027
negative regulation of gene expression GO:0010629 387 0.026
actin filament based process GO:0030029 220 0.026
axon guidance GO:0007411 233 0.026
tube morphogenesis GO:0035239 191 0.026
regulation of transcription from rna polymerase ii promoter GO:0006357 378 0.026
regulation of protein metabolic process GO:0051246 256 0.026
regulation of cellular amino acid metabolic process GO:0006521 0 0.026
positive regulation of phosphorus metabolic process GO:0010562 139 0.026
cellular catabolic process GO:0044248 372 0.026
mapk cascade GO:0000165 107 0.025
imaginal disc derived appendage morphogenesis GO:0035114 395 0.025
positive regulation of cell communication GO:0010647 250 0.025
negative regulation of nitrogen compound metabolic process GO:0051172 265 0.025
cellular response to chemical stimulus GO:0070887 199 0.025
cellular response to organic substance GO:0071310 132 0.025
organic substance catabolic process GO:1901575 308 0.025
regulation of cellular amine metabolic process GO:0033238 3 0.025
regulation of mitotic cell cycle GO:0007346 190 0.024
imaginal disc derived wing morphogenesis GO:0007476 337 0.024
regulation of multicellular organismal development GO:2000026 414 0.024
protein phosphorylation GO:0006468 169 0.024
response to hexose GO:0009746 3 0.024
epithelial cell differentiation GO:0030855 322 0.024
cell adhesion GO:0007155 136 0.024
amine metabolic process GO:0009308 12 0.023
regulation of cell differentiation GO:0045595 302 0.023
regulation of cellular protein metabolic process GO:0032268 243 0.023
actin cytoskeleton organization GO:0030036 206 0.023
enzyme linked receptor protein signaling pathway GO:0007167 179 0.023
post embryonic appendage morphogenesis GO:0035120 385 0.023
regulation of transport GO:0051049 181 0.023
imaginal disc derived appendage development GO:0048737 399 0.023
regulation of intracellular signal transduction GO:1902531 236 0.023
nuclear division GO:0000280 332 0.023
ribonucleotide metabolic process GO:0009259 145 0.023
regionalization GO:0003002 416 0.023
signal transduction by phosphorylation GO:0023014 107 0.023
positive regulation of gene expression GO:0010628 290 0.022
compound eye development GO:0048749 307 0.022
response to nutrient levels GO:0031667 114 0.022
cognition GO:0050890 141 0.022
organelle assembly GO:0070925 198 0.022
establishment of localization in cell GO:0051649 402 0.022
organic substance transport GO:0071702 257 0.022
macromolecular complex assembly GO:0065003 256 0.022
synapse assembly GO:0007416 143 0.022
salivary gland development GO:0007431 162 0.022
eye morphogenesis GO:0048592 260 0.022
kidney development GO:0001822 3 0.021
negative regulation of biosynthetic process GO:0009890 277 0.021
regulation of mapk cascade GO:0043408 92 0.021
cyclic nucleotide biosynthetic process GO:0009190 25 0.021
cell death GO:0008219 279 0.021
wing disc morphogenesis GO:0007472 344 0.021
cellular response to carbohydrate stimulus GO:0071322 4 0.021
negative regulation of rna biosynthetic process GO:1902679 240 0.021
regulation of cell death GO:0010941 173 0.020
negative regulation of cellular biosynthetic process GO:0031327 277 0.020
regulation of cellular ketone metabolic process GO:0010565 3 0.020
response to lipopolysaccharide GO:0032496 4 0.020
response to ecdysone GO:0035075 34 0.020
sensory perception GO:0007600 196 0.020
response to extracellular stimulus GO:0009991 116 0.020
morphogenesis of an epithelium GO:0002009 276 0.020
negative regulation of signaling GO:0023057 219 0.020
biological adhesion GO:0022610 138 0.020
protein complex assembly GO:0006461 200 0.020
eye development GO:0001654 323 0.019
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 116 0.019
positive regulation of multicellular organismal process GO:0051240 143 0.019
exocrine system development GO:0035272 162 0.019
triglyceride biosynthetic process GO:0019432 2 0.019
ribose phosphate biosynthetic process GO:0046390 28 0.019
heart development GO:0007507 82 0.019
cellular amine metabolic process GO:0044106 12 0.019
negative regulation of transcription dna templated GO:0045892 237 0.019
developmental growth GO:0048589 280 0.019
camera type eye development GO:0043010 4 0.019
intracellular transport GO:0046907 228 0.019
apoptotic process GO:0006915 159 0.018
positive regulation of molecular function GO:0044093 136 0.018
regulation of nervous system development GO:0051960 248 0.018
salivary gland morphogenesis GO:0007435 145 0.018
posttranscriptional regulation of gene expression GO:0010608 145 0.018
cellular component assembly involved in morphogenesis GO:0010927 151 0.018
protein transport GO:0015031 155 0.018
single organism catabolic process GO:0044712 228 0.018
chemosensory behavior GO:0007635 106 0.018
taxis GO:0042330 304 0.018
synapse organization GO:0050808 196 0.018
gland development GO:0048732 191 0.018
stem cell proliferation GO:0072089 88 0.018
positive regulation of lyase activity GO:0051349 10 0.018
lipid metabolic process GO:0006629 121 0.018
rna localization GO:0006403 115 0.018
response to radiation GO:0009314 155 0.017
gland morphogenesis GO:0022612 145 0.017
regulation of developmental growth GO:0048638 174 0.017
regulation of cellular component biogenesis GO:0044087 201 0.017
regulation of epidermal growth factor receptor signaling pathway GO:0042058 42 0.017
regulation of gene expression epigenetic GO:0040029 128 0.017
positive regulation of macromolecule biosynthetic process GO:0010557 283 0.017
regulation of nucleotide metabolic process GO:0006140 62 0.017
ribonucleotide biosynthetic process GO:0009260 28 0.017
negative regulation of nucleic acid templated transcription GO:1903507 240 0.017
neutral lipid biosynthetic process GO:0046460 2 0.017
cyclic nucleotide metabolic process GO:0009187 28 0.017
positive regulation of phosphorylation GO:0042327 87 0.017
cell division GO:0051301 248 0.017
positive regulation of transcription dna templated GO:0045893 266 0.017
locomotory behavior GO:0007626 176 0.017
regulation of programmed cell death GO:0043067 152 0.017
protein localization GO:0008104 284 0.016
negative regulation of signal transduction GO:0009968 206 0.016
protein complex biogenesis GO:0070271 201 0.016
photoreceptor cell axon guidance GO:0072499 23 0.016
response to organic cyclic compound GO:0014070 89 0.016
sensory organ morphogenesis GO:0090596 260 0.016
neuroblast proliferation GO:0007405 74 0.016
positive regulation of rna biosynthetic process GO:1902680 266 0.016
positive regulation of nucleic acid templated transcription GO:1903508 266 0.016
membrane organization GO:0061024 112 0.016
transmembrane transport GO:0055085 139 0.016
mitotic nuclear division GO:0007067 213 0.016
dendrite development GO:0016358 204 0.016
connective tissue development GO:0061448 3 0.016
camera type eye morphogenesis GO:0048593 2 0.016
behavioral response to ethanol GO:0048149 49 0.016
response to biotic stimulus GO:0009607 294 0.016
chemical homeostasis GO:0048878 92 0.016
single organism intracellular transport GO:1902582 207 0.016
response to alcohol GO:0097305 95 0.016
muscle structure development GO:0061061 224 0.016
acetylcholine metabolic process GO:0008291 2 0.016
regulation of anatomical structure morphogenesis GO:0022603 242 0.015
cellular response to molecule of bacterial origin GO:0071219 3 0.015
cell cycle phase transition GO:0044770 140 0.015
regulation of anatomical structure size GO:0090066 163 0.015
multi organism behavior GO:0051705 175 0.015
cellular macromolecule localization GO:0070727 220 0.015
cyclic purine nucleotide metabolic process GO:0052652 25 0.015
response to external biotic stimulus GO:0043207 293 0.015
telencephalon development GO:0021537 2 0.015
regulation of purine nucleotide biosynthetic process GO:1900371 14 0.015
positive regulation of catalytic activity GO:0043085 118 0.015
regulation of organelle organization GO:0033043 196 0.015
regulation of purine nucleotide metabolic process GO:1900542 62 0.015
circulatory system development GO:0072359 82 0.015
organic cyclic compound catabolic process GO:1901361 168 0.015
learning or memory GO:0007611 141 0.015
response to organophosphorus GO:0046683 2 0.015
camp biosynthetic process GO:0006171 17 0.015
cell recognition GO:0008037 102 0.014
synaptic growth at neuromuscular junction GO:0051124 119 0.014
nucleobase containing compound catabolic process GO:0034655 165 0.014
cellular lipid metabolic process GO:0044255 83 0.014
positive regulation of mapk cascade GO:0043410 63 0.014
negative regulation of rna metabolic process GO:0051253 251 0.014
positive regulation of cyclic nucleotide biosynthetic process GO:0030804 9 0.014
proteolysis GO:0006508 192 0.014
regulation of apoptotic process GO:0042981 130 0.014
epidermal growth factor receptor signaling pathway GO:0007173 58 0.014
cellular nitrogen compound catabolic process GO:0044270 165 0.014
limb development GO:0060173 1 0.014
cellular macromolecular complex assembly GO:0034622 153 0.014
heterocycle catabolic process GO:0046700 166 0.014
positive regulation of protein metabolic process GO:0051247 128 0.014
ras protein signal transduction GO:0007265 88 0.014
nucleoside phosphate biosynthetic process GO:1901293 34 0.014
vitamin biosynthetic process GO:0009110 1 0.014
notch signaling pathway GO:0007219 120 0.014
hormone catabolic process GO:0042447 3 0.014
immune response GO:0006955 246 0.014
single organism cellular localization GO:1902580 180 0.014
aromatic compound catabolic process GO:0019439 166 0.013
positive regulation of cell migration GO:0030335 2 0.013
positive regulation of cell motility GO:2000147 3 0.013
multi multicellular organism process GO:0044706 123 0.013
regulation of catabolic process GO:0009894 170 0.013
mesenchymal cell development GO:0014031 1 0.013
cellular response to oxygen containing compound GO:1901701 79 0.013
regulation of mitotic cell cycle phase transition GO:1901990 130 0.013
growth GO:0040007 359 0.013
anatomical structure homeostasis GO:0060249 97 0.013
actin filament organization GO:0007015 126 0.013
cell cell adhesion GO:0098609 26 0.013
head development GO:0060322 135 0.013
cardiovascular system development GO:0072358 82 0.013
regulation of erbb signaling pathway GO:1901184 42 0.013
tissue morphogenesis GO:0048729 297 0.013
negative regulation of cellular component organization GO:0051129 108 0.013
multicellular organismal aging GO:0010259 140 0.013
embryonic development via the syncytial blastoderm GO:0001700 148 0.013
sensory perception of chemical stimulus GO:0007606 116 0.013
synaptic transmission GO:0007268 288 0.013
hindbrain development GO:0030902 2 0.013
purine ribonucleotide biosynthetic process GO:0009152 28 0.013
regulation of cell proliferation GO:0042127 163 0.013
neurotransmitter metabolic process GO:0042133 2 0.013
positive regulation of intracellular signal transduction GO:1902533 116 0.013
positive regulation of purine nucleotide metabolic process GO:1900544 55 0.013
regulation of response to external stimulus GO:0032101 115 0.013
neuron recognition GO:0008038 101 0.013
regulation of cell shape GO:0008360 113 0.012
glycosyl compound metabolic process GO:1901657 127 0.012
nucleoside phosphate metabolic process GO:0006753 162 0.012
photoreceptor cell differentiation GO:0046530 170 0.012
chromatin modification GO:0016568 147 0.012
regulation of camp biosynthetic process GO:0030817 12 0.012
endomembrane system organization GO:0010256 119 0.012
compound eye morphogenesis GO:0001745 249 0.012
cell motility GO:0048870 251 0.012
regulation of cellular localization GO:0060341 136 0.012
regulation of response to stress GO:0080134 200 0.012
ribonucleotide catabolic process GO:0009261 109 0.012
l amino acid import GO:0043092 2 0.012
learning GO:0007612 75 0.012
neural precursor cell proliferation GO:0061351 75 0.012
gene silencing GO:0016458 138 0.012
axis specification GO:0009798 167 0.012
negative regulation of developmental process GO:0051093 201 0.012
response to starvation GO:0042594 97 0.012
positive regulation of developmental process GO:0051094 143 0.012
regulation of cyclic nucleotide metabolic process GO:0030799 13 0.012
small gtpase mediated signal transduction GO:0007264 88 0.012
erbb signaling pathway GO:0038127 58 0.012
defense response GO:0006952 300 0.012
monocarboxylic acid transport GO:0015718 3 0.012
mesenchymal cell differentiation GO:0048762 1 0.012
nucleoside phosphate catabolic process GO:1901292 110 0.012
cellular response to biotic stimulus GO:0071216 4 0.012
courtship behavior GO:0007619 68 0.012
establishment of protein localization GO:0045184 163 0.012
translation GO:0006412 69 0.012
regulation of protein modification process GO:0031399 112 0.012
response to endogenous stimulus GO:0009719 119 0.012
negative regulation of cellular macromolecule biosynthetic process GO:2000113 267 0.012
regulation of synaptic growth at neuromuscular junction GO:0008582 89 0.012
mitotic cell cycle phase transition GO:0044772 138 0.012
cellular homeostasis GO:0019725 80 0.012
organonitrogen compound catabolic process GO:1901565 128 0.012
nucleoside triphosphate catabolic process GO:0009143 108 0.012
larval behavior GO:0030537 42 0.012
regulation of cell development GO:0060284 215 0.012
chromosome organization GO:0051276 360 0.012
regulation of growth GO:0040008 233 0.012
positive regulation of cellular protein metabolic process GO:0032270 118 0.012
negative regulation of macromolecule biosynthetic process GO:0010558 270 0.012
larval development GO:0002164 104 0.012
positive regulation of adenylate cyclase activity involved in g protein coupled receptor signaling pathway GO:0010579 7 0.012
columnar cuboidal epithelial cell differentiation GO:0002065 256 0.012
negative regulation of cellular protein metabolic process GO:0032269 85 0.012
secretion by cell GO:0032940 101 0.012
camp metabolic process GO:0046058 19 0.012
developmental maturation GO:0021700 172 0.011
ion transport GO:0006811 145 0.011
spindle organization GO:0007051 253 0.011
cellular protein complex assembly GO:0043623 71 0.011
meiotic cell cycle GO:0051321 171 0.011
rna processing GO:0006396 147 0.011
epithelial cell development GO:0002064 274 0.011
regulation of small gtpase mediated signal transduction GO:0051056 93 0.011
organophosphate biosynthetic process GO:0090407 46 0.011
compound eye photoreceptor cell differentiation GO:0001751 140 0.011
localization of cell GO:0051674 257 0.011
single organism membrane organization GO:0044802 93 0.011
purine ribonucleotide metabolic process GO:0009150 145 0.011
response to other organism GO:0051707 293 0.011
regulation of adenylate cyclase activity GO:0045761 12 0.011
retina development in camera type eye GO:0060041 4 0.011
ribonucleoside metabolic process GO:0009119 127 0.011
peptidyl amino acid modification GO:0018193 105 0.011
epithelial tube morphogenesis GO:0060562 88 0.011
meiotic nuclear division GO:0007126 151 0.011
reproductive behavior GO:0019098 122 0.011
positive regulation of rna metabolic process GO:0051254 271 0.011
mating behavior GO:0007617 106 0.011
spermatogenesis GO:0007283 200 0.011
sensory perception of pain GO:0019233 4 0.011
kidney morphogenesis GO:0060993 3 0.011
nephron epithelium development GO:0072009 3 0.011
acetylcholine catabolic process GO:0006581 1 0.011
cellular response to lipopolysaccharide GO:0071222 3 0.011
kidney epithelium development GO:0072073 3 0.011
purine nucleoside catabolic process GO:0006152 112 0.011
cellular response to starvation GO:0009267 61 0.011
negative regulation of protein metabolic process GO:0051248 85 0.011
negative regulation of cell differentiation GO:0045596 143 0.011
chromatin organization GO:0006325 207 0.011
nucleotide biosynthetic process GO:0009165 34 0.011
flight behavior GO:0007629 26 0.011
regulation of cellular catabolic process GO:0031329 157 0.011
nephron tubule development GO:0072080 3 0.011
asymmetric stem cell division GO:0098722 49 0.011
mrna processing GO:0006397 104 0.011
regulation of immune system process GO:0002682 176 0.011
regulation of epithelial cell proliferation GO:0050678 4 0.011
purine containing compound biosynthetic process GO:0072522 30 0.011
olfactory behavior GO:0042048 97 0.011
embryonic morphogenesis GO:0048598 206 0.011
mrna metabolic process GO:0016071 124 0.011
response to bacterium GO:0009617 198 0.011
regulation of circadian rhythm GO:0042752 49 0.011
regulation of cell morphogenesis GO:0022604 163 0.011
immune system process GO:0002376 347 0.011
associative learning GO:0008306 65 0.011
regulation of cell cycle process GO:0010564 181 0.011
regulation of protein phosphorylation GO:0001932 64 0.011
negative regulation of multicellular organismal process GO:0051241 142 0.010
gtp catabolic process GO:0006184 72 0.010
central nervous system development GO:0007417 201 0.010
adult locomotory behavior GO:0008344 76 0.010
cellular protein localization GO:0034613 160 0.010
cation transport GO:0006812 110 0.010
nitrogen compound transport GO:0071705 85 0.010
dorsal ventral pattern formation GO:0009953 133 0.010
regulation of cyclic nucleotide biosynthetic process GO:0030802 13 0.010
gliogenesis GO:0042063 80 0.010
negative regulation of molecular function GO:0044092 51 0.010
regulation of i kappab kinase nf kappab signaling GO:0043122 2 0.010
purine nucleoside triphosphate catabolic process GO:0009146 108 0.010
positive regulation of cell differentiation GO:0045597 64 0.010
ethanolamine containing compound metabolic process GO:0042439 4 0.010
dendrite morphogenesis GO:0048813 199 0.010
cellular response to nutrient levels GO:0031669 62 0.010
cation transmembrane transport GO:0098655 88 0.010
positive regulation of cellular component organization GO:0051130 156 0.010
motor neuron axon guidance GO:0008045 58 0.010

SP2353 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.032
nervous system disease DOID:863 0 0.024
disease of metabolism DOID:0014667 0 0.016
cardiovascular system disease DOID:1287 0 0.016
sensory system disease DOID:0050155 0 0.015
musculoskeletal system disease DOID:17 0 0.014
eye and adnexa disease DOID:1492 0 0.013
eye disease DOID:5614 0 0.013
central nervous system disease DOID:331 0 0.010