Drosophila melanogaster

98 known processes

scrt (Dmel_CG1130)

scratch

(Aliases: Scrt,anon-EST:Liang-1.31,Dmel\CG1130,BcDNA:RH71479,clone 1.67,CG1130,anon-EST:Liang-1.67,anon-WO02059370.57,clone 1.31)

scrt biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
eye development GO:0001654 323 0.469
Fly
regulation of multicellular organismal development GO:2000026 414 0.337
Mouse
photoreceptor cell differentiation GO:0046530 170 0.274
post embryonic appendage morphogenesis GO:0035120 385 0.264
respiratory system development GO:0060541 213 0.258
Fly
compound eye development GO:0048749 307 0.253
Fly
microtubule based transport GO:0010970 42 0.251
imaginal disc derived appendage morphogenesis GO:0035114 395 0.243
imaginal disc derived appendage development GO:0048737 399 0.226
dendrite development GO:0016358 204 0.207
negative regulation of cell differentiation GO:0045596 143 0.204
Fly
positive regulation of signal transduction GO:0009967 223 0.164
appendage development GO:0048736 401 0.154
enzyme linked receptor protein signaling pathway GO:0007167 179 0.152
positive regulation of cell communication GO:0010647 250 0.152
positive regulation of response to stimulus GO:0048584 323 0.144
regionalization GO:0003002 416 0.141
appendage morphogenesis GO:0035107 397 0.137
negative regulation of multicellular organismal process GO:0051241 142 0.134
immune response GO:0006955 246 0.132
positive regulation of signaling GO:0023056 243 0.131
wing disc morphogenesis GO:0007472 344 0.127
single organism intracellular transport GO:1902582 207 0.126
sensory organ morphogenesis GO:0090596 260 0.123
body morphogenesis GO:0010171 2 0.122
dendrite morphogenesis GO:0048813 199 0.119
regulation of transcription from rna polymerase ii promoter GO:0006357 378 0.112
cell proliferation GO:0008283 299 0.109
Fly
eye photoreceptor cell fate commitment GO:0042706 37 0.107
gland development GO:0048732 191 0.104
regulation of embryonic development GO:0045995 68 0.099
cell fate specification GO:0001708 71 0.098
Fly
olfactory behavior GO:0042048 97 0.095
Fly
intracellular signal transduction GO:0035556 300 0.093
establishment or maintenance of cell polarity GO:0007163 167 0.092
associative learning GO:0008306 65 0.088
chemosensory behavior GO:0007635 106 0.085
Fly
axis specification GO:0009798 167 0.085
cytokinesis GO:0000910 90 0.082
establishment of organelle localization GO:0051656 122 0.080
imaginal disc derived wing morphogenesis GO:0007476 337 0.080
regulation of cell differentiation GO:0045595 302 0.079
Mouse Fly
oocyte construction GO:0007308 112 0.078
regulation of phosphate metabolic process GO:0019220 210 0.073
compound eye morphogenesis GO:0001745 249 0.072
immune system process GO:0002376 347 0.072
microtubule based movement GO:0007018 51 0.071
compound eye photoreceptor fate commitment GO:0001752 36 0.068
intracellular transport GO:0046907 228 0.067
death GO:0016265 284 0.067
Worm
cellular nitrogen compound catabolic process GO:0044270 165 0.066
regulation of cellular catabolic process GO:0031329 157 0.066
ras protein signal transduction GO:0007265 88 0.065
glycosyl compound catabolic process GO:1901658 112 0.064
regulation of cell proliferation GO:0042127 163 0.064
neuron projection guidance GO:0097485 241 0.064
regulation of cellular protein metabolic process GO:0032268 243 0.062
Fly
olfactory learning GO:0008355 56 0.059
axon guidance GO:0007411 233 0.059
positive regulation of transcription from rna polymerase ii promoter GO:0045944 204 0.058
Fly
regulation of cellular amino acid metabolic process GO:0006521 0 0.057
autophagy GO:0006914 108 0.057
negative regulation of cell development GO:0010721 62 0.057
purine nucleoside metabolic process GO:0042278 127 0.056
kidney development GO:0001822 3 0.056
phosphorylation GO:0016310 294 0.055
axonogenesis GO:0007409 290 0.054
regulation of bmp signaling pathway GO:0030510 23 0.054
positive regulation of intracellular signal transduction GO:1902533 116 0.054
regulation of intracellular signal transduction GO:1902531 236 0.053
cytoskeleton dependent intracellular transport GO:0030705 44 0.053
mitotic cytokinesis GO:0000281 50 0.053
negative regulation of cellular metabolic process GO:0031324 382 0.053
protein complex biogenesis GO:0070271 201 0.053
nucleobase containing compound catabolic process GO:0034655 165 0.051
aromatic compound catabolic process GO:0019439 166 0.048
cell cell adhesion GO:0098609 26 0.048
actin cytoskeleton organization GO:0030036 206 0.047
ribonucleoside triphosphate metabolic process GO:0009199 119 0.047
oocyte differentiation GO:0009994 145 0.047
central nervous system development GO:0007417 201 0.047
Fly
regulation of phosphorus metabolic process GO:0051174 210 0.047
eye morphogenesis GO:0048592 260 0.046
response to external biotic stimulus GO:0043207 293 0.046
dorsal ventral pattern formation GO:0009953 133 0.046
organelle localization GO:0051640 148 0.045
regulation of anatomical structure morphogenesis GO:0022603 242 0.045
camera type eye development GO:0043010 4 0.043
positive regulation of nucleic acid templated transcription GO:1903508 266 0.043
Fly
anterior posterior pattern specification GO:0009952 136 0.043
regulation of epidermal growth factor receptor signaling pathway GO:0042058 42 0.043
imaginal disc derived leg morphogenesis GO:0007480 80 0.042
positive regulation of cellular biosynthetic process GO:0031328 316 0.042
Fly
ovarian follicle cell development GO:0030707 248 0.041
oocyte axis specification GO:0007309 108 0.041
negative regulation of developmental process GO:0051093 201 0.041
Fly
gliogenesis GO:0042063 80 0.040
negative regulation of response to stimulus GO:0048585 258 0.040
neurological system process GO:0050877 358 0.040
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 116 0.040
organophosphate catabolic process GO:0046434 112 0.039
regulation of reproductive process GO:2000241 54 0.038
heterocycle catabolic process GO:0046700 166 0.037
regulation of protein metabolic process GO:0051246 256 0.037
Fly
asymmetric cell division GO:0008356 37 0.037
positive regulation of biosynthetic process GO:0009891 316 0.036
Fly
establishment of localization in cell GO:0051649 402 0.036
cytoskeleton dependent cytokinesis GO:0061640 81 0.035
cellular catabolic process GO:0044248 372 0.034
regulation of cellular ketone metabolic process GO:0010565 3 0.034
purine ribonucleotide catabolic process GO:0009154 109 0.034
head development GO:0060322 135 0.033
Fly
regulation of notch signaling pathway GO:0008593 100 0.033
ribonucleoside metabolic process GO:0009119 127 0.033
response to gravity GO:0009629 26 0.033
Fly
connective tissue development GO:0061448 3 0.032
developmental maturation GO:0021700 172 0.032
purine ribonucleotide metabolic process GO:0009150 145 0.032
tube development GO:0035295 244 0.032
Fly
organonitrogen compound metabolic process GO:1901564 318 0.032
regulation of catalytic activity GO:0050790 185 0.032
immune effector process GO:0002252 98 0.032
negative regulation of cellular component organization GO:0051129 108 0.032
protein phosphorylation GO:0006468 169 0.031
regulation of peptidase activity GO:0052547 39 0.031
purine ribonucleoside triphosphate catabolic process GO:0009207 108 0.031
eye photoreceptor cell differentiation GO:0001754 145 0.031
regulation of proteolysis GO:0030162 87 0.030
sensory perception of sound GO:0007605 56 0.030
regulation of anatomical structure size GO:0090066 163 0.029
regulation of phosphorylation GO:0042325 147 0.029
positive regulation of macromolecule metabolic process GO:0010604 405 0.029
Fly
glycosyl compound metabolic process GO:1901657 127 0.029
purine containing compound metabolic process GO:0072521 155 0.028
epithelial cell migration GO:0010631 148 0.028
Fly
segmentation GO:0035282 207 0.028
hindbrain development GO:0030902 2 0.028
embryonic morphogenesis GO:0048598 206 0.027
Fly
nucleoside triphosphate metabolic process GO:0009141 120 0.027
epithelial cell differentiation GO:0030855 322 0.027
vesicle mediated transport GO:0016192 381 0.026
organic cyclic compound catabolic process GO:1901361 168 0.026
leg disc morphogenesis GO:0007478 80 0.026
homeostatic process GO:0042592 199 0.026
single organism catabolic process GO:0044712 228 0.026
purine nucleoside triphosphate metabolic process GO:0009144 119 0.026
programmed cell death GO:0012501 257 0.026
Worm
r7 cell differentiation GO:0045466 43 0.025
regulation of cell death GO:0010941 173 0.025
Worm
cytoplasmic microtubule organization GO:0031122 22 0.025
morphogenesis of embryonic epithelium GO:0016331 94 0.025
organic substance catabolic process GO:1901575 308 0.025
compound eye photoreceptor cell differentiation GO:0001751 140 0.025
branching involved in open tracheal system development GO:0060446 45 0.025
Fly
negative regulation of signaling GO:0023057 219 0.024
nucleoside phosphate metabolic process GO:0006753 162 0.024
purine ribonucleoside triphosphate metabolic process GO:0009205 119 0.024
cellular protein modification process GO:0006464 438 0.024
Fly
gravitaxis GO:0042332 26 0.024
Fly
morphogenesis of an epithelium GO:0002009 276 0.023
Fly
regulation of multi organism process GO:0043900 131 0.023
gtp metabolic process GO:0046039 72 0.023
axon development GO:0061564 297 0.023
negative regulation of cellular protein metabolic process GO:0032269 85 0.023
humoral immune response GO:0006959 117 0.022
actin filament based process GO:0030029 220 0.022
nucleoside metabolic process GO:0009116 127 0.022
purine nucleotide metabolic process GO:0006163 146 0.021
regulation of wnt signaling pathway GO:0030111 68 0.021
cell death GO:0008219 279 0.021
Worm
carboxylic acid metabolic process GO:0019752 92 0.021
positive regulation of molecular function GO:0044093 136 0.021
gland morphogenesis GO:0022612 145 0.021
negative regulation of cellular macromolecule biosynthetic process GO:2000113 267 0.021
calcium ion homeostasis GO:0055074 23 0.020
response to biotic stimulus GO:0009607 294 0.020
negative regulation of molecular function GO:0044092 51 0.020
notch signaling pathway GO:0007219 120 0.020
response to alcohol GO:0097305 95 0.020
retina development in camera type eye GO:0060041 4 0.020
epithelial cell development GO:0002064 274 0.020
macromolecular complex assembly GO:0065003 256 0.020
mapk cascade GO:0000165 107 0.020
cell adhesion GO:0007155 136 0.020
cytoplasmic transport GO:0016482 130 0.019
skin development GO:0043588 65 0.019
regulation of neurogenesis GO:0050767 158 0.019
Mouse
regulation of retinal cell programmed cell death GO:0046668 18 0.019
organ growth GO:0035265 56 0.019
positive regulation of mapk cascade GO:0043410 63 0.019
purine nucleoside triphosphate catabolic process GO:0009146 108 0.019
erbb signaling pathway GO:0038127 58 0.019
negative regulation of cell communication GO:0010648 223 0.019
stem cell development GO:0048864 79 0.018
Fly
catabolic process GO:0009056 409 0.018
negative regulation of cell proliferation GO:0008285 69 0.018
ion homeostasis GO:0050801 55 0.018
dephosphorylation GO:0016311 51 0.018
biological adhesion GO:0022610 138 0.018
positive regulation of phosphorylation GO:0042327 87 0.018
negative regulation of epidermal growth factor receptor signaling pathway GO:0042059 29 0.018
positive regulation of phosphorus metabolic process GO:0010562 139 0.018
regulation of erbb signaling pathway GO:1901184 42 0.018
regulation of immune system process GO:0002682 176 0.018
small molecule metabolic process GO:0044281 305 0.018
peripheral nervous system development GO:0007422 52 0.018
organophosphate metabolic process GO:0019637 195 0.018
mitotic nuclear division GO:0007067 213 0.017
imaginal disc pattern formation GO:0007447 91 0.017
negative regulation of nitrogen compound metabolic process GO:0051172 265 0.017
regulation of hydrolase activity GO:0051336 97 0.017
chaeta development GO:0022416 97 0.017
regulation of catabolic process GO:0009894 170 0.017
protein localization GO:0008104 284 0.017
single organism cell adhesion GO:0098602 47 0.017
transcription from rna polymerase ii promoter GO:0006366 368 0.017
peptidyl tyrosine modification GO:0018212 24 0.017
nucleotide catabolic process GO:0009166 109 0.017
brain development GO:0007420 120 0.017
Fly
positive regulation of catabolic process GO:0009896 105 0.017
dna metabolic process GO:0006259 227 0.017
Fly
neural retina development GO:0003407 4 0.017
regulation of immune response GO:0050776 118 0.017
cell fate determination GO:0001709 91 0.017
Fly
protein complex assembly GO:0006461 200 0.017
salivary gland development GO:0007431 162 0.016
regulation of cellular response to stress GO:0080135 89 0.016
positive regulation of catalytic activity GO:0043085 118 0.016
tripartite regional subdivision GO:0007351 103 0.016
positive regulation of cell proliferation GO:0008284 47 0.016
exocrine system development GO:0035272 162 0.016
negative regulation of nervous system development GO:0051961 92 0.016
epidermal growth factor receptor signaling pathway GO:0007173 58 0.016
cation transport GO:0006812 110 0.016
positive regulation of nitrogen compound metabolic process GO:0051173 354 0.016
Fly
endomembrane system organization GO:0010256 119 0.016
regulation of response to biotic stimulus GO:0002831 63 0.016
negative regulation of epithelial cell proliferation GO:0050680 4 0.016
epidermis development GO:0008544 65 0.016
forebrain development GO:0030900 2 0.016
blastoderm segmentation GO:0007350 159 0.016
cell division GO:0051301 248 0.016
Fly
negative regulation of signal transduction GO:0009968 206 0.016
muscle structure development GO:0061061 224 0.016
Fly
apoptotic process GO:0006915 159 0.016
protein modification process GO:0036211 438 0.015
Fly
regulation of epithelial cell proliferation GO:0050678 4 0.015
positive regulation of nucleobase containing compound metabolic process GO:0045935 332 0.015
Fly
regulation of cellular component biogenesis GO:0044087 201 0.015
positive regulation of phosphate metabolic process GO:0045937 139 0.015
purine containing compound catabolic process GO:0072523 112 0.015
guanosine containing compound catabolic process GO:1901069 74 0.015
embryonic pattern specification GO:0009880 174 0.015
negative regulation of programmed cell death GO:0043069 72 0.015
Worm
negative regulation of rna biosynthetic process GO:1902679 240 0.015
tissue morphogenesis GO:0048729 297 0.015
Fly
regulation of epidermal growth factor activated receptor activity GO:0007176 4 0.015
negative regulation of gene expression GO:0010629 387 0.015
negative regulation of transcription dna templated GO:0045892 237 0.014
organic substance transport GO:0071702 257 0.014
guanosine containing compound metabolic process GO:1901068 74 0.014
nucleotide metabolic process GO:0009117 161 0.014
negative regulation of apoptotic process GO:0043066 63 0.014
amine metabolic process GO:0009308 12 0.014
nucleoside triphosphate catabolic process GO:0009143 108 0.014
digestive system development GO:0055123 149 0.014
Fly
purine ribonucleoside catabolic process GO:0046130 112 0.014
renal system development GO:0072001 72 0.014
Fly
proteolysis GO:0006508 192 0.014
regulation of cell development GO:0060284 215 0.014
Mouse
cell maturation GO:0048469 144 0.014
anterior posterior axis specification GO:0009948 109 0.014
negative regulation of transcription from rna polymerase ii promoter GO:0000122 119 0.014
negative regulation of erk1 and erk2 cascade GO:0070373 3 0.013
cellular amine metabolic process GO:0044106 12 0.013
immune system development GO:0002520 57 0.013
sister chromatid segregation GO:0000819 92 0.013
columnar cuboidal epithelial cell differentiation GO:0002065 256 0.013
regulation of cellular component size GO:0032535 98 0.013
homophilic cell adhesion via plasma membrane adhesion molecules GO:0007156 18 0.013
startle response GO:0001964 16 0.013
single organism biosynthetic process GO:0044711 206 0.013
Fly
digestive tract morphogenesis GO:0048546 127 0.013
Fly
ribonucleotide catabolic process GO:0009261 109 0.013
developmental growth involved in morphogenesis GO:0060560 65 0.013
protein maturation GO:0051604 71 0.013
endosomal transport GO:0016197 44 0.013
small gtpase mediated signal transduction GO:0007264 88 0.013
pole plasm mrna localization GO:0019094 49 0.013
neuron fate commitment GO:0048663 50 0.013
regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090092 38 0.013
carbohydrate derivative catabolic process GO:1901136 118 0.012
regulation of mitotic cell cycle GO:0007346 190 0.012
nucleoside phosphate catabolic process GO:1901292 110 0.012
positive regulation of protein metabolic process GO:0051247 128 0.012
Fly
purine ribonucleoside metabolic process GO:0046128 127 0.012
regulation of epithelial cell differentiation GO:0030856 4 0.012
response to other organism GO:0051707 293 0.012
salivary gland morphogenesis GO:0007435 145 0.012
cell cycle arrest GO:0007050 4 0.012
ribonucleoside catabolic process GO:0042454 112 0.012
purine nucleoside catabolic process GO:0006152 112 0.012
tube morphogenesis GO:0035239 191 0.012
Fly
regulation of transferase activity GO:0051338 58 0.011
neuron recognition GO:0008038 101 0.011
regulation of mrna metabolic process GO:1903311 72 0.011
larval development GO:0002164 104 0.011
filopodium assembly GO:0046847 33 0.011
response to organic substance GO:0010033 284 0.011
learning GO:0007612 75 0.011
anterior posterior axis specification embryo GO:0008595 103 0.011
regulation of cell morphogenesis involved in differentiation GO:0010769 61 0.011
photoreceptor cell fate commitment GO:0046552 41 0.011
rna splicing via transesterification reactions GO:0000375 73 0.011
positive regulation of cell death GO:0010942 69 0.011
nephron epithelium development GO:0072009 3 0.011
hemopoiesis GO:0030097 46 0.011
gene silencing GO:0016458 138 0.011
regulation of gtp catabolic process GO:0033124 44 0.011
protein processing GO:0016485 68 0.011
ncrna metabolic process GO:0034660 43 0.011
regulation of endopeptidase activity GO:0052548 36 0.011
endocytosis GO:0006897 310 0.011
positive regulation of immune system process GO:0002684 68 0.010
regulation of mitosis GO:0007088 56 0.010
regulation of nucleotide catabolic process GO:0030811 48 0.010
nucleobase containing small molecule metabolic process GO:0055086 174 0.010
signal transduction by phosphorylation GO:0023014 107 0.010
regulation of cell projection assembly GO:0060491 30 0.010
positive regulation of cellular catabolic process GO:0031331 95 0.010

scrt disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.010
nervous system disease DOID:863 0 0.010