Drosophila melanogaster

236 known processes

Dad (Dmel_CG5201)

Daughters against dpp

(Aliases: CG5201,DAD,EP(3)3196,EP3196,Dad1,anon-EST:fe1F5,l(3)j1E4,dad,Dmel\CG5201,1883)

Dad biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
synapse assembly GO:0007416 143 0.999
neuron projection guidance GO:0097485 241 0.999
synaptic growth at neuromuscular junction GO:0051124 119 0.998
regulation of bmp signaling pathway GO:0030510 23 0.994
Human Mouse
muscle structure development GO:0061061 224 0.988
post embryonic appendage morphogenesis GO:0035120 385 0.984
tissue morphogenesis GO:0048729 297 0.983
endodermal cell differentiation GO:0035987 3 0.981
Fly
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 65 0.977
regulation of synapse structure and activity GO:0050803 128 0.976
cell proliferation GO:0008283 299 0.974
Human Fly
axonogenesis GO:0007409 290 0.973
morphogenesis of embryonic epithelium GO:0016331 94 0.969
growth GO:0040007 359 0.968
regulation of synapse organization GO:0050807 110 0.967
malpighian tubule morphogenesis GO:0007443 44 0.966
morphogenesis of an epithelium GO:0002009 276 0.965
axon development GO:0061564 297 0.961
urogenital system development GO:0001655 72 0.959
muscle organ development GO:0007517 127 0.959
negative regulation of gene expression GO:0010629 387 0.958
Human Rat Fly
axon guidance GO:0007411 233 0.957
regulation of synaptic growth at neuromuscular junction GO:0008582 89 0.956
cellular protein modification process GO:0006464 438 0.953
Human Mouse
negative regulation of developmental process GO:0051093 201 0.951
brain development GO:0007420 120 0.950
Fly
regulation of cell proliferation GO:0042127 163 0.941
Human Fly
regulation of transforming growth factor beta receptor signaling pathway GO:0017015 6 0.941
dorsal ventral pattern formation GO:0009953 133 0.939
Human Fly
positive regulation of nucleobase containing compound metabolic process GO:0045935 332 0.938
Fly
neuromuscular junction development GO:0007528 149 0.934
negative regulation of synaptic growth at neuromuscular junction GO:0045886 39 0.931
epithelial cell development GO:0002064 274 0.931
Fly
dorsal closure GO:0007391 79 0.931
regulation of anatomical structure morphogenesis GO:0022603 242 0.930
Fly
tube morphogenesis GO:0035239 191 0.927
appendage development GO:0048736 401 0.925
synapse organization GO:0050808 196 0.920
regulation of synapse assembly GO:0051963 94 0.919
regulation of multicellular organismal development GO:2000026 414 0.917
positive regulation of nitrogen compound metabolic process GO:0051173 354 0.916
Fly
malpighian tubule development GO:0072002 64 0.910
larval development GO:0002164 104 0.898
positive regulation of signal transduction GO:0009967 223 0.898
imaginal disc derived appendage development GO:0048737 399 0.896
bmp signaling pathway GO:0030509 27 0.895
regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090092 38 0.895
regionalization GO:0003002 416 0.894
anterior posterior pattern specification GO:0009952 136 0.894
positive regulation of bmp signaling pathway GO:0030513 5 0.888
regulation of transcription from rna polymerase ii promoter GO:0006357 378 0.887
epithelial cell differentiation GO:0030855 322 0.886
Fly
regulation of erbb signaling pathway GO:1901184 42 0.883
embryonic pattern specification GO:0009880 174 0.883
Human Fly
cell division GO:0051301 248 0.879
Fly
homeostatic process GO:0042592 199 0.877
negative regulation of multicellular organismal process GO:0051241 142 0.867
positive regulation of transcription dna templated GO:0045893 266 0.864
Fly
blastoderm segmentation GO:0007350 159 0.861
Fly
cell growth GO:0016049 108 0.854
regulation of developmental growth GO:0048638 174 0.846
chemotaxis GO:0006935 249 0.846
embryonic development via the syncytial blastoderm GO:0001700 148 0.840
regulation of epithelial cell proliferation GO:0050678 4 0.837
positive regulation of synapse assembly GO:0051965 29 0.826
Fly
cardiovascular system development GO:0072358 82 0.814
Mouse
striated muscle cell differentiation GO:0051146 90 0.811
positive regulation of rna biosynthetic process GO:1902680 266 0.810
Fly
embryonic hindgut morphogenesis GO:0048619 48 0.810
epithelial cell migration GO:0010631 148 0.809
positive regulation of response to stimulus GO:0048584 323 0.801
embryo development ending in birth or egg hatching GO:0009792 152 0.800
enteroendocrine cell differentiation GO:0035883 1 0.793
endodermal cell fate commitment GO:0001711 3 0.787
Fly
activation of protein kinase activity GO:0032147 12 0.781
positive regulation of pathway restricted smad protein phosphorylation GO:0010862 1 0.775
positive regulation of macromolecule metabolic process GO:0010604 405 0.773
Human Fly
columnar cuboidal epithelial cell development GO:0002066 249 0.770
Fly
regulation of protein phosphorylation GO:0001932 64 0.767
Human Mouse
embryonic morphogenesis GO:0048598 206 0.754
positive regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090100 9 0.753
muscle cell differentiation GO:0042692 103 0.751
kidney development GO:0001822 3 0.748
Mouse
dendrite morphogenesis GO:0048813 199 0.746
regulation of cellular component size GO:0032535 98 0.731
imaginal disc derived wing vein morphogenesis GO:0008586 44 0.715
Fly
zygotic determination of anterior posterior axis embryo GO:0007354 27 0.712
anterior posterior pattern specification imaginal disc GO:0007448 16 0.706
oocyte development GO:0048599 124 0.699
regulation of protein metabolic process GO:0051246 256 0.695
Human Mouse
developmental growth GO:0048589 280 0.691
response to transforming growth factor beta GO:0071559 18 0.677
aging GO:0007568 143 0.673
Fly
death GO:0016265 284 0.671
Human
phosphorylation GO:0016310 294 0.665
kidney epithelium development GO:0072073 3 0.664
Mouse
cellular amine metabolic process GO:0044106 12 0.664
regulation of cell differentiation GO:0045595 302 0.662
regulation of anatomical structure size GO:0090066 163 0.655
regulation of cellular amino acid metabolic process GO:0006521 0 0.655
stem cell differentiation GO:0048863 117 0.645
regulation of epithelial cell differentiation GO:0030856 4 0.645
enzyme linked receptor protein signaling pathway GO:0007167 179 0.641
genital disc development GO:0035215 44 0.635
response to abiotic stimulus GO:0009628 341 0.632
positive regulation of transcription from rna polymerase ii promoter GO:0045944 204 0.631
Fly
regulation of localization GO:0032879 275 0.630
positive regulation of synaptic growth at neuromuscular junction GO:0045887 26 0.628
Fly
exocrine system development GO:0035272 162 0.621
appendage morphogenesis GO:0035107 397 0.620
morphogenesis of a branching structure GO:0001763 45 0.603
response to growth factor GO:0070848 31 0.597
carbohydrate derivative biosynthetic process GO:1901137 85 0.597
regulation of cellular localization GO:0060341 136 0.596
cell motility GO:0048870 251 0.595
regulation of epidermal growth factor receptor signaling pathway GO:0042058 42 0.588
taxis GO:0042330 304 0.586
positive regulation of transport GO:0051050 92 0.582
ameboidal type cell migration GO:0001667 151 0.580
establishment of localization in cell GO:0051649 402 0.571
transforming growth factor beta receptor signaling pathway GO:0007179 16 0.570
tube development GO:0035295 244 0.569
positive regulation of cell communication GO:0010647 250 0.566
stem cell proliferation GO:0072089 88 0.563
pathway restricted smad protein phosphorylation GO:0060389 1 0.560
Human Mouse
renal system development GO:0072001 72 0.554
protein localization GO:0008104 284 0.550
Human
regulation of phosphate metabolic process GO:0019220 210 0.549
regulation of growth GO:0040008 233 0.548
tissue homeostasis GO:0001894 36 0.546
developmental maturation GO:0021700 172 0.546
imaginal disc derived appendage morphogenesis GO:0035114 395 0.546
embryonic axis specification GO:0000578 107 0.543
Human
tripartite regional subdivision GO:0007351 103 0.541
regulation of intracellular signal transduction GO:1902531 236 0.540
carboxylic acid metabolic process GO:0019752 92 0.536
apoptotic process GO:0006915 159 0.535
Human
response to organic substance GO:0010033 284 0.531
compound eye morphogenesis GO:0001745 249 0.526
Fly
bmp signaling pathway involved in malpighian tubule cell chemotaxis GO:0061353 3 0.524
negative regulation of signal transduction GO:0009968 206 0.521
hematopoietic or lymphoid organ development GO:0048534 57 0.521
positive regulation of macromolecule biosynthetic process GO:0010557 283 0.516
Fly
positive regulation of cellular biosynthetic process GO:0031328 316 0.512
Fly
imaginal disc pattern formation GO:0007447 91 0.512
regulation of cell size GO:0008361 63 0.506
single organismal cell cell adhesion GO:0016337 45 0.497
Human Mouse
axis specification GO:0009798 167 0.494
Human Fly
positive regulation of cellular component organization GO:0051130 156 0.494
Fly
regulation of cell death GO:0010941 173 0.486
Human
protein phosphorylation GO:0006468 169 0.486
Human Mouse
imaginal disc derived wing morphogenesis GO:0007476 337 0.481
cell fate specification GO:0001708 71 0.479
Fly
positive regulation of cell proliferation GO:0008284 47 0.478
regulation of neuron projection development GO:0010975 69 0.477
positive regulation of rna metabolic process GO:0051254 271 0.477
Fly
stem cell division GO:0017145 69 0.474
Fly
single organism biosynthetic process GO:0044711 206 0.472
regulation of cell cycle GO:0051726 291 0.471
Fly
cellular ketone metabolic process GO:0042180 24 0.468
epithelial cell proliferation GO:0050673 15 0.462
negative regulation of synapse assembly GO:0051964 39 0.461
germ line stem cell maintenance GO:0030718 50 0.461
actin filament bundle organization GO:0061572 28 0.460
regulation of phosphorus metabolic process GO:0051174 210 0.459
developmental growth involved in morphogenesis GO:0060560 65 0.450
positive regulation of signaling GO:0023056 243 0.446
anterior malpighian tubule development GO:0061327 12 0.446
gland morphogenesis GO:0022612 145 0.446
negative regulation of cell differentiation GO:0045596 143 0.444
compound eye development GO:0048749 307 0.441
Fly
cell death GO:0008219 279 0.440
Human
intracellular signal transduction GO:0035556 300 0.438
negative regulation of nitrogen compound metabolic process GO:0051172 265 0.437
Human Rat
cell elongation involved in imaginal disc derived wing morphogenesis GO:0090254 5 0.436
regulation of embryonic development GO:0045995 68 0.436
cell migration GO:0016477 238 0.434
positive regulation of nucleic acid templated transcription GO:1903508 266 0.434
Fly
epithelial structure maintenance GO:0010669 17 0.433
nephron morphogenesis GO:0072028 3 0.433
positive regulation of phosphorylation GO:0042327 87 0.429
male gamete generation GO:0048232 201 0.428
nephron tubule morphogenesis GO:0072078 3 0.425
regulation of mitotic cell cycle GO:0007346 190 0.422
Fly
response to endogenous stimulus GO:0009719 119 0.418
organ growth GO:0035265 56 0.411
endoderm formation GO:0001706 3 0.410
Fly
dendrite development GO:0016358 204 0.408
erbb signaling pathway GO:0038127 58 0.405
digestive tract development GO:0048565 149 0.405
secretion by cell GO:0032940 101 0.394
single organism behavior GO:0044708 391 0.389
organelle localization GO:0051640 148 0.387
negative regulation of growth GO:0045926 84 0.386
somatic stem cell maintenance GO:0035019 14 0.384
Fly
anterior posterior axis specification embryo GO:0008595 103 0.383
cellular macromolecule localization GO:0070727 220 0.379
Human
gastrulation GO:0007369 70 0.378
Fly
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 116 0.368
regulation of apoptotic process GO:0042981 130 0.365
Human
wing disc morphogenesis GO:0007472 344 0.361
positive regulation of phosphate metabolic process GO:0045937 139 0.354
circulatory system development GO:0072359 82 0.352
Mouse
cellular response to organic substance GO:0071310 132 0.350
immune system process GO:0002376 347 0.349
Human
unidimensional cell growth GO:0009826 15 0.348
connective tissue development GO:0061448 3 0.346
gland development GO:0048732 191 0.346
lipid localization GO:0010876 54 0.344
actin filament organization GO:0007015 126 0.342
positive regulation of cell migration GO:0030335 2 0.339
regulation of cell morphogenesis GO:0022604 163 0.339
cellular response to growth factor stimulus GO:0071363 30 0.339
regulation of neuron differentiation GO:0045664 103 0.338
negative regulation of transforming growth factor beta receptor signaling pathway GO:0030512 4 0.336
regulation of protein kinase activity GO:0045859 51 0.334
kidney morphogenesis GO:0060993 3 0.333
vesicle mediated transport GO:0016192 381 0.331
programmed cell death GO:0012501 257 0.330
Human
stress activated mapk cascade GO:0051403 52 0.328
head development GO:0060322 135 0.327
Fly
cell rearrangement involved in malpighian tubule morphogenesis GO:0061334 3 0.323
digestive tract morphogenesis GO:0048546 127 0.320
cellular amino acid metabolic process GO:0006520 61 0.318
central nervous system development GO:0007417 201 0.318
Fly
stem cell maintenance GO:0019827 67 0.314
organic acid metabolic process GO:0006082 103 0.311
cellular response to transforming growth factor beta stimulus GO:0071560 18 0.311
negative regulation of developmental growth GO:0048640 64 0.310
chorion containing eggshell formation GO:0007304 105 0.306
positive regulation of cellular protein metabolic process GO:0032270 118 0.304
Human
regulation of phosphatidylinositol 3 kinase activity GO:0043551 2 0.303
mapk cascade GO:0000165 107 0.302
cardiac cell fate commitment GO:0060911 17 0.298
endocytosis GO:0006897 310 0.298
multicellular organismal homeostasis GO:0048871 41 0.297
embryonic hemopoiesis GO:0035162 26 0.295
oxoacid metabolic process GO:0043436 103 0.293
positive regulation of phosphorus metabolic process GO:0010562 139 0.293
secretion GO:0046903 109 0.290
nephron tubule development GO:0072080 3 0.290
hemopoiesis GO:0030097 46 0.290
immune system development GO:0002520 57 0.286
single organism cellular localization GO:1902580 180 0.285
regulation of cell cycle process GO:0010564 181 0.284
Fly
cell cycle phase transition GO:0044770 140 0.284
Fly
cell adhesion GO:0007155 136 0.282
Human Mouse
nephron epithelium morphogenesis GO:0072088 3 0.278
regulation of neurogenesis GO:0050767 158 0.276
wing disc anterior posterior pattern formation GO:0048100 5 0.276
Fly
organic substance transport GO:0071702 257 0.273
negative regulation of cell proliferation GO:0008285 69 0.271
Human
renal tubule morphogenesis GO:0061333 44 0.269
negative regulation of nucleobase containing compound metabolic process GO:0045934 261 0.265
Human Rat
peptide metabolic process GO:0006518 80 0.265
hindgut morphogenesis GO:0007442 58 0.264
negative regulation of epithelial cell proliferation GO:0050680 4 0.264
positive regulation of multicellular organismal process GO:0051240 143 0.261
Fly
neuroblast proliferation GO:0007405 74 0.258
regulation of phosphorylation GO:0042325 147 0.257
response to wounding GO:0009611 94 0.256
positive regulation of cellular amino acid metabolic process GO:0045764 0 0.253
protein modification process GO:0036211 438 0.248
Human Mouse
regulation of transport GO:0051049 181 0.246
cell proliferation involved in imaginal disc derived wing morphogenesis GO:0090255 2 0.245
Fly
regulation of pathway restricted smad protein phosphorylation GO:0060393 1 0.245
Human
regulation of protein localization GO:0032880 76 0.233
positive regulation of protein metabolic process GO:0051247 128 0.233
Human
stress activated protein kinase signaling cascade GO:0031098 55 0.232
sensory organ morphogenesis GO:0090596 260 0.232
Fly
striated muscle tissue development GO:0014706 27 0.231
Mouse
renal tubule development GO:0061326 64 0.225
regulation of multi organism process GO:0043900 131 0.224
small molecule metabolic process GO:0044281 305 0.224
epidermal growth factor receptor signaling pathway GO:0007173 58 0.222
columnar cuboidal epithelial cell differentiation GO:0002065 256 0.220
Fly
regulation of lipid metabolic process GO:0019216 15 0.217
ovarian follicle cell development GO:0030707 248 0.214
Fly
endomembrane system organization GO:0010256 119 0.209
positive regulation of cell motility GO:2000147 3 0.209
cellular response to endogenous stimulus GO:0071495 80 0.208
negative regulation of molecular function GO:0044092 51 0.207
Human
negative regulation of cellular component organization GO:0051129 108 0.204
negative regulation of response to stimulus GO:0048585 258 0.203
ion homeostasis GO:0050801 55 0.202
mesoderm formation GO:0001707 21 0.202
cell maturation GO:0048469 144 0.201
anterior posterior axis specification GO:0009948 109 0.200
morphogenesis of larval imaginal disc epithelium GO:0016335 5 0.199
negative regulation of phosphorylation GO:0042326 35 0.199
Human Mouse
regulation of vesicle mediated transport GO:0060627 59 0.199
anatomical structure homeostasis GO:0060249 97 0.198
regulation of cellular response to growth factor stimulus GO:0090287 13 0.198
sex differentiation GO:0007548 81 0.196
leg disc development GO:0035218 92 0.194
Fly
negative regulation of signaling GO:0023057 219 0.194
positive regulation of growth GO:0045927 75 0.190
Fly
negative regulation of cell communication GO:0010648 223 0.189
positive regulation of lipid metabolic process GO:0045834 4 0.189
transcription from rna polymerase ii promoter GO:0006366 368 0.188
regulation of mitosis GO:0007088 56 0.187
regulation of cellular component movement GO:0051270 42 0.187
endoderm development GO:0007492 6 0.186
Fly
developmental cell growth GO:0048588 52 0.186
cellular lipid metabolic process GO:0044255 83 0.185
protein modification by small protein conjugation GO:0032446 79 0.184
Human
chromatin organization GO:0006325 207 0.182
regulation of kinase activity GO:0043549 53 0.181
negative regulation of cellular protein metabolic process GO:0032269 85 0.180
Human Mouse
body morphogenesis GO:0010171 2 0.180
carbohydrate derivative metabolic process GO:1901135 217 0.179
regulation of actin filament polymerization GO:0030833 25 0.179
regulation of cell development GO:0060284 215 0.178
epithelial tube morphogenesis GO:0060562 88 0.178
regulation of stem cell proliferation GO:0072091 40 0.176
determination of dorsal ventral asymmetry GO:0048262 3 0.175
heart morphogenesis GO:0003007 32 0.170
Mouse
epidermal cell differentiation GO:0009913 51 0.170
mesoderm morphogenesis GO:0048332 22 0.170
epidermis development GO:0008544 65 0.169
organonitrogen compound metabolic process GO:1901564 318 0.166
regulation of cell growth GO:0001558 43 0.165
lipid metabolic process GO:0006629 121 0.165
negative regulation of nervous system development GO:0051961 92 0.164
gliogenesis GO:0042063 80 0.162
morphogenesis of a branching epithelium GO:0061138 45 0.159
synaptic transmission GO:0007268 288 0.157
positive regulation of developmental growth GO:0048639 62 0.157
Fly
regulation of cell shape GO:0008360 113 0.156
oocyte differentiation GO:0009994 145 0.155
activation of mapk activity GO:0000187 9 0.154
nephron development GO:0072006 3 0.153
regulation of catalytic activity GO:0050790 185 0.153
Human
regulation of cellular amine metabolic process GO:0033238 3 0.153
regulation of organ morphogenesis GO:2000027 78 0.151
Fly
decapentaplegic signaling pathway GO:0008101 19 0.150
positive regulation of protein phosphorylation GO:0001934 34 0.149
embryonic organ development GO:0048568 50 0.148
positive regulation of cellular component biogenesis GO:0044089 80 0.147
Fly
organ formation GO:0048645 39 0.146
pericardial nephrocyte differentiation GO:0061320 9 0.144
positive regulation of cell differentiation GO:0045597 64 0.141
motor neuron axon guidance GO:0008045 58 0.141
regulation of mapk cascade GO:0043408 92 0.140
establishment of imaginal disc derived wing hair orientation GO:0001737 24 0.140
positive regulation of gene expression GO:0010628 290 0.138
Fly
regulation of transferase activity GO:0051338 58 0.137
Human
signal transduction by phosphorylation GO:0023014 107 0.137
positive regulation of protein localization to plasma membrane GO:1903078 3 0.137
determination of ventral identity GO:0048264 1 0.136
negative regulation of cellular biosynthetic process GO:0031327 277 0.134
Human Rat
positive regulation of protein modification process GO:0031401 58 0.132
Human
regulation of axonogenesis GO:0050770 32 0.131
segmentation GO:0035282 207 0.127
Fly
cell fate commitment involved in formation of primary germ layer GO:0060795 10 0.127
Fly
positive regulation of cellular amine metabolic process GO:0033240 0 0.127
negative regulation of biosynthetic process GO:0009890 277 0.126
Human Rat
regulation of stress activated mapk cascade GO:0032872 41 0.126
regulation of cellular response to stress GO:0080135 89 0.126
cellular component assembly involved in morphogenesis GO:0010927 151 0.126
eggshell formation GO:0030703 105 0.124
establishment of protein localization GO:0045184 163 0.122
embryonic ectodermal digestive tract development GO:0048611 4 0.122
organophosphate metabolic process GO:0019637 195 0.122
epithelium migration GO:0090132 148 0.122
heart development GO:0007507 82 0.119
Mouse
cytokinesis GO:0000910 90 0.119
negative regulation of cellular metabolic process GO:0031324 382 0.118
Human Mouse Rat Fly
protein complex biogenesis GO:0070271 201 0.118
Human
histone modification GO:0016570 106 0.116
single organism cell adhesion GO:0098602 47 0.116
Human Mouse
photoreceptor cell axon guidance GO:0072499 23 0.115
protein modification by small protein conjugation or removal GO:0070647 106 0.114
Human
regulation of neuron apoptotic process GO:0043523 16 0.113
positive regulation of developmental process GO:0051094 143 0.113
Fly
positive regulation of transferase activity GO:0051347 26 0.113
regulation of organelle organization GO:0033043 196 0.112
salivary gland morphogenesis GO:0007435 145 0.111
germ line stem cell division GO:0042078 25 0.110
Fly
nuclear division GO:0000280 332 0.110
digestive system development GO:0055123 149 0.109
negative regulation of transcription from rna polymerase ii promoter GO:0000122 119 0.109
Human
positive regulation of phagocytosis engulfment GO:0060100 1 0.109
regulation of response to stress GO:0080134 200 0.109
negative regulation of phosphate metabolic process GO:0045936 45 0.107
Human Mouse
limb development GO:0060173 1 0.107
regulation of actin filament based process GO:0032970 42 0.107
regulation of cellular protein metabolic process GO:0032268 243 0.107
Human Mouse
wing disc pattern formation GO:0035222 66 0.106
Fly
smad protein import into nucleus GO:0007184 11 0.105
response to oxygen containing compound GO:1901700 200 0.104
negative regulation of organelle organization GO:0010639 56 0.103
stem cell development GO:0048864 79 0.103
forebrain development GO:0030900 2 0.103
positive regulation of molecular function GO:0044093 136 0.103
positive regulation of biosynthetic process GO:0009891 316 0.103
Fly
adult behavior GO:0030534 137 0.102
protein ubiquitination GO:0016567 70 0.101
Human
multi multicellular organism process GO:0044706 123 0.101
Worm
transmembrane transport GO:0055085 139 0.101
meiotic cell cycle GO:0051321 171 0.100
negative regulation of macromolecule biosynthetic process GO:0010558 270 0.099
Human Rat
positive regulation of axon extension GO:0045773 2 0.097
positive regulation of mapk cascade GO:0043410 63 0.097
defense response to bacterium GO:0042742 178 0.096
organelle fission GO:0048285 340 0.096
ribonucleotide metabolic process GO:0009259 145 0.095
regulation of cellular ketone metabolic process GO:0010565 3 0.095
negative regulation of hormone biosynthetic process GO:0032353 1 0.095
negative regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090101 18 0.095
determination of adult lifespan GO:0008340 137 0.094
Fly
establishment of organelle localization GO:0051656 122 0.094
positive regulation of cell projection organization GO:0031346 29 0.093
myotube differentiation GO:0014902 46 0.093
regulation of muscle organ development GO:0048634 13 0.091
hindbrain development GO:0030902 2 0.091
cellular protein localization GO:0034613 160 0.091
Human
localization of cell GO:0051674 257 0.090
negative regulation of protein metabolic process GO:0051248 85 0.090
Human Mouse
positive regulation of catabolic process GO:0009896 105 0.090
Human
negative regulation of rna metabolic process GO:0051253 251 0.090
Human Rat
regulation of establishment of protein localization GO:0070201 61 0.088
regulation of nuclear transcribed mrna poly a tail shortening GO:0060211 4 0.088
positive regulation of peptidyl tyrosine phosphorylation GO:0050731 4 0.087
regulation of nervous system development GO:0051960 248 0.087
negative regulation of neurogenesis GO:0050768 53 0.087
telencephalon development GO:0021537 2 0.086
regulation of immune system process GO:0002682 176 0.085
mesoderm development GO:0007498 78 0.085
amine metabolic process GO:0009308 12 0.085
regulation of stress activated protein kinase signaling cascade GO:0070302 42 0.084
embryonic heart tube development GO:0035050 22 0.084
mrna processing GO:0006397 104 0.083
feeding behavior GO:0007631 50 0.083
nephron epithelium development GO:0072009 3 0.083
intracellular transport GO:0046907 228 0.083
negative regulation of apoptotic process GO:0043066 63 0.083
Human
cellular response to organonitrogen compound GO:0071417 36 0.082
regulation of nucleotide metabolic process GO:0006140 62 0.082
regulation of programmed cell death GO:0043067 152 0.080
Human
receptor clustering GO:0043113 3 0.080
regulation of heart morphogenesis GO:2000826 3 0.080
negative regulation of cellular response to growth factor stimulus GO:0090288 6 0.080
positive regulation of immune system process GO:0002684 68 0.079
skin development GO:0043588 65 0.079
chemical homeostasis GO:0048878 92 0.078
regulation of molecular function GO:0065009 217 0.078
Human
cytokinetic cell separation GO:0000920 1 0.077
regulation of protein modification by small protein conjugation or removal GO:1903320 25 0.077
Human
regulation of cellular component biogenesis GO:0044087 201 0.077
glandular epithelial cell differentiation GO:0002067 1 0.077
respiratory system development GO:0060541 213 0.076
covalent chromatin modification GO:0016569 106 0.076
regulation of protein modification process GO:0031399 112 0.076
Human Mouse
small gtpase mediated signal transduction GO:0007264 88 0.075
wnt signaling pathway GO:0016055 98 0.075
positive regulation of gliogenesis GO:0014015 5 0.074
glycoprotein biosynthetic process GO:0009101 41 0.074
regulation of cell motility GO:2000145 23 0.073
protein localization to nucleus GO:0034504 55 0.072
regulation of response to external stimulus GO:0032101 115 0.072
negative regulation of cellular catabolic process GO:0031330 34 0.072
Fly
response to peptide hormone GO:0043434 29 0.071
positive regulation of cell development GO:0010720 61 0.070
photoreceptor cell differentiation GO:0046530 170 0.070
regulation of cell projection organization GO:0031344 92 0.070
regulation of intracellular transport GO:0032386 64 0.070
muscle cell development GO:0055001 50 0.070
notch signaling pathway GO:0007219 120 0.069
compound eye photoreceptor development GO:0042051 78 0.069
negative regulation of epidermal growth factor receptor signaling pathway GO:0042059 29 0.069
wing and notum subfield formation GO:0035309 13 0.068
positive regulation of calcium ion transport GO:0051928 4 0.068
imaginal disc derived leg segmentation GO:0036011 26 0.068
myotube cell development GO:0014904 3 0.068
regulation of protein transport GO:0051223 57 0.067
single organism membrane organization GO:0044802 93 0.067
protein transport GO:0015031 155 0.067
extracellular structure organization GO:0043062 46 0.066
sensory perception of chemical stimulus GO:0007606 116 0.066
phagocytosis GO:0006909 215 0.065
regulation of nuclear division GO:0051783 58 0.064
spermatogenesis GO:0007283 200 0.063
cell activation GO:0001775 9 0.063
positive regulation of muscle organ development GO:0048636 6 0.063
response to nitrogen compound GO:1901698 90 0.063
oocyte axis specification GO:0007309 108 0.063
response to glucose GO:0009749 2 0.062
negative regulation of protein modification process GO:0031400 29 0.062
Human Mouse
extracellular matrix organization GO:0030198 32 0.062
positive regulation of protein complex assembly GO:0031334 22 0.062

Dad disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.310
Human
cardiovascular system disease DOID:1287 0 0.128
Human
artery disease DOID:0050828 0 0.110
vascular disease DOID:178 0 0.110