Drosophila melanogaster

70 known processes

Ercc1 (Dmel_CG10215)

CG10215 gene product from transcript CG10215-RA

(Aliases: ERCC1,CG10215,Dmel\CG10215)

Ercc1 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
dna repair GO:0006281 54 0.804
double strand break repair GO:0006302 26 0.501
Mouse
negative regulation of cell cycle phase transition GO:1901988 103 0.450
cellular response to dna damage stimulus GO:0006974 223 0.370
double strand break repair via homologous recombination GO:0000724 13 0.303
dna metabolic process GO:0006259 227 0.211
nucleotide excision repair GO:0006289 8 0.199
recombinational repair GO:0000725 13 0.187
mitotic dna damage checkpoint GO:0044773 74 0.175
negative regulation of cell cycle GO:0045786 116 0.170
negative regulation of cell cycle process GO:0010948 109 0.169
negative regulation of nitrogen compound metabolic process GO:0051172 265 0.144
response to radiation GO:0009314 155 0.140
Mouse
mitotic g2 m transition checkpoint GO:0044818 70 0.139
cell cycle phase transition GO:0044770 140 0.134
mitotic cell cycle checkpoint GO:0007093 88 0.132
negative regulation of mitotic cell cycle phase transition GO:1901991 103 0.132
dna damage checkpoint GO:0000077 78 0.128
g2 dna damage checkpoint GO:0031572 69 0.121
mitotic cell cycle phase transition GO:0044772 138 0.120
mitotic dna integrity checkpoint GO:0044774 75 0.103
mitotic g2 dna damage checkpoint GO:0007095 69 0.103
negative regulation of mitotic cell cycle GO:0045930 109 0.094
regulation of cell cycle phase transition GO:1901987 130 0.089
protein modification process GO:0036211 438 0.085
cell cycle checkpoint GO:0000075 95 0.082
reciprocal meiotic recombination GO:0007131 19 0.082
double strand break repair via nonhomologous end joining GO:0006303 5 0.082
negative regulation of rna biosynthetic process GO:1902679 240 0.078
cellular protein modification process GO:0006464 438 0.075
chromosome segregation GO:0007059 157 0.075
anatomical structure homeostasis GO:0060249 97 0.074
non recombinational repair GO:0000726 7 0.069
response to ionizing radiation GO:0010212 32 0.068
Mouse
regulation of mitotic cell cycle GO:0007346 190 0.068
regulation of mitotic cell cycle phase transition GO:1901990 130 0.066
negative regulation of nucleobase containing compound metabolic process GO:0045934 261 0.061
meiotic chromosome segregation GO:0045132 59 0.061
dna recombination GO:0006310 32 0.060
response to light stimulus GO:0009416 124 0.059
Mouse
response to abiotic stimulus GO:0009628 341 0.059
Mouse
negative regulation of transcription dna templated GO:0045892 237 0.058
negative regulation of cellular biosynthetic process GO:0031327 277 0.055
organelle fission GO:0048285 340 0.053
negative regulation of macromolecule biosynthetic process GO:0010558 270 0.050
chromatin silencing GO:0006342 76 0.049
neurological system process GO:0050877 358 0.049
negative regulation of cellular metabolic process GO:0031324 382 0.049
positive regulation of response to stimulus GO:0048584 323 0.048
chromatin organization GO:0006325 207 0.046
meiotic cell cycle process GO:1903046 132 0.042
dna integrity checkpoint GO:0031570 81 0.041
heterocycle catabolic process GO:0046700 166 0.041
regulation of cell cycle process GO:0010564 181 0.041
regulation of transcription from rna polymerase ii promoter GO:0006357 378 0.041
phosphorylation GO:0016310 294 0.039
cellular response to radiation GO:0071478 52 0.039
learning or memory GO:0007611 141 0.038
death GO:0016265 284 0.038
regulation of cell cycle GO:0051726 291 0.038
negative regulation of gene expression GO:0010629 387 0.037
negative regulation of cellular macromolecule biosynthetic process GO:2000113 267 0.037
growth GO:0040007 359 0.037
Mouse
vesicle mediated transport GO:0016192 381 0.036
small molecule metabolic process GO:0044281 305 0.036
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 116 0.035
double strand break repair via synthesis dependent strand annealing GO:0045003 6 0.034
positive regulation of signal transduction GO:0009967 223 0.034
positive regulation of signaling GO:0023056 243 0.033
endocytosis GO:0006897 310 0.032
catabolic process GO:0009056 409 0.032
aromatic compound catabolic process GO:0019439 166 0.032
dna double strand break processing GO:0000729 3 0.032
negative regulation of rna metabolic process GO:0051253 251 0.030
response to other organism GO:0051707 293 0.030
developmental growth GO:0048589 280 0.030
organic substance catabolic process GO:1901575 308 0.029
negative regulation of response to stimulus GO:0048585 258 0.029
postreplication repair GO:0006301 2 0.029
cellular catabolic process GO:0044248 372 0.028
organic cyclic compound catabolic process GO:1901361 168 0.028
negative regulation of nucleic acid templated transcription GO:1903507 240 0.028
single organism biosynthetic process GO:0044711 206 0.027
transcription from rna polymerase ii promoter GO:0006366 368 0.027
rna localization GO:0006403 115 0.026
regulation of double strand break repair GO:2000779 3 0.026
cellular macromolecule catabolic process GO:0044265 136 0.026
single organism behavior GO:0044708 391 0.026
protein phosphorylation GO:0006468 169 0.026
nuclear division GO:0000280 332 0.025
macromolecule catabolic process GO:0009057 161 0.025
locomotory behavior GO:0007626 176 0.025
organonitrogen compound metabolic process GO:1901564 318 0.024
amine metabolic process GO:0009308 12 0.024
regulation of cellular response to stress GO:0080135 89 0.024
nucleoside catabolic process GO:0009164 112 0.024
positive regulation of cell communication GO:0010647 250 0.024
reciprocal dna recombination GO:0035825 19 0.023
intracellular signal transduction GO:0035556 300 0.023
response to biotic stimulus GO:0009607 294 0.023
nucleoside phosphate metabolic process GO:0006753 162 0.022
dorsal ventral pattern formation GO:0009953 133 0.022
programmed cell death GO:0012501 257 0.022
response to external biotic stimulus GO:0043207 293 0.022
regulation of phosphate metabolic process GO:0019220 210 0.022
defense response GO:0006952 300 0.022
response to organic substance GO:0010033 284 0.021
body morphogenesis GO:0010171 2 0.021
adult behavior GO:0030534 137 0.021
negative regulation of signaling GO:0023057 219 0.021
proteolysis GO:0006508 192 0.020
negative regulation of cell communication GO:0010648 223 0.020
aging GO:0007568 143 0.020
Mouse
negative regulation of biosynthetic process GO:0009890 277 0.020
enzyme linked receptor protein signaling pathway GO:0007167 179 0.020
cellular amine metabolic process GO:0044106 12 0.019
regulation of response to stress GO:0080134 200 0.019
ribonucleotide metabolic process GO:0009259 145 0.019
regulation of cell death GO:0010941 173 0.019
regulation of apoptotic process GO:0042981 130 0.019
modification dependent macromolecule catabolic process GO:0043632 79 0.019
purine nucleoside catabolic process GO:0006152 112 0.019
appendage development GO:0048736 401 0.019
defense response to other organism GO:0098542 225 0.019
chromatin modification GO:0016568 147 0.019
regulation of multicellular organismal development GO:2000026 414 0.018
anterior posterior pattern specification GO:0009952 136 0.018
signal transduction in response to dna damage GO:0042770 3 0.018
cell aging GO:0007569 2 0.018
Mouse
regionalization GO:0003002 416 0.018
cellular nitrogen compound catabolic process GO:0044270 165 0.018
appendage morphogenesis GO:0035107 397 0.018
positive regulation of nucleic acid templated transcription GO:1903508 266 0.017
regulation of cellular ketone metabolic process GO:0010565 3 0.017
regulation of nervous system development GO:0051960 248 0.017
regulation of programmed cell death GO:0043067 152 0.017
cell death GO:0008219 279 0.016
regulation of response to dna damage stimulus GO:2001020 23 0.016
axis specification GO:0009798 167 0.016
gland development GO:0048732 191 0.016
exocrine system development GO:0035272 162 0.016
telomere organization GO:0032200 21 0.016
protein maturation GO:0051604 71 0.016
imaginal disc derived wing morphogenesis GO:0007476 337 0.016
mitotic nuclear division GO:0007067 213 0.016
ribonucleoside catabolic process GO:0042454 112 0.016
nucleobase containing compound catabolic process GO:0034655 165 0.016
translesion synthesis GO:0019985 2 0.015
imaginal disc derived appendage morphogenesis GO:0035114 395 0.015
centrosome organization GO:0051297 163 0.015
wing disc morphogenesis GO:0007472 344 0.015
embryo development ending in birth or egg hatching GO:0009792 152 0.015
telomere maintenance GO:0000723 21 0.015
purine nucleotide catabolic process GO:0006195 109 0.015
imaginal disc derived appendage development GO:0048737 399 0.015
cell proliferation GO:0008283 299 0.015
Mouse
connective tissue development GO:0061448 3 0.015
nucleobase containing small molecule metabolic process GO:0055086 174 0.015
rna processing GO:0006396 147 0.015
learning GO:0007612 75 0.015
dna conformation change GO:0071103 105 0.015
multicellular organismal homeostasis GO:0048871 41 0.014
purine ribonucleotide metabolic process GO:0009150 145 0.014
cellular macromolecule localization GO:0070727 220 0.014
eye development GO:0001654 323 0.014
apoptotic process GO:0006915 159 0.014
germarium derived egg chamber formation GO:0007293 101 0.014
positive regulation of cellular biosynthetic process GO:0031328 316 0.014
olfactory learning GO:0008355 56 0.014
regulation of catabolic process GO:0009894 170 0.014
compound eye photoreceptor cell differentiation GO:0001751 140 0.014
regulation of cell cycle g1 s phase transition GO:1902806 23 0.014
rna splicing GO:0008380 83 0.013
nucleoside triphosphate catabolic process GO:0009143 108 0.013
compound eye development GO:0048749 307 0.013
oxoacid metabolic process GO:0043436 103 0.013
regulation of cellular amine metabolic process GO:0033238 3 0.013
positive regulation of intracellular signal transduction GO:1902533 116 0.013
regulation of phosphorus metabolic process GO:0051174 210 0.013
organophosphate metabolic process GO:0019637 195 0.013
regulation of phosphorylation GO:0042325 147 0.013
ras protein signal transduction GO:0007265 88 0.012
dna synthesis involved in dna repair GO:0000731 5 0.012
cellular amino acid metabolic process GO:0006520 61 0.012
cellular response to abiotic stimulus GO:0071214 58 0.012
response to oxygen containing compound GO:1901700 200 0.012
eye morphogenesis GO:0048592 260 0.012
cell recognition GO:0008037 102 0.012
homeostatic process GO:0042592 199 0.012
male gamete generation GO:0048232 201 0.012
Mouse
protein dna complex subunit organization GO:0071824 86 0.012
cellular ketone metabolic process GO:0042180 24 0.012
rhythmic behavior GO:0007622 76 0.012
protein complex assembly GO:0006461 200 0.012
regulation of gene expression epigenetic GO:0040029 128 0.012
positive regulation of developmental process GO:0051094 143 0.012
negative regulation of apoptotic process GO:0043066 63 0.012
immune response GO:0006955 246 0.012
Mouse
regulation of cellular amino acid metabolic process GO:0006521 0 0.012
regulation of dna recombination GO:0000018 4 0.012
sex differentiation GO:0007548 81 0.012
Mouse
multicellular organismal aging GO:0010259 140 0.012
Mouse
response to bacterium GO:0009617 198 0.012
negative regulation of signal transduction GO:0009968 206 0.012
larval development GO:0002164 104 0.012
regulation of innate immune response GO:0045088 71 0.011
female meiotic division GO:0007143 70 0.011
chorion containing eggshell formation GO:0007304 105 0.011
protein modification by small protein conjugation GO:0032446 79 0.011
negative regulation of molecular function GO:0044092 51 0.011
regulation of neurogenesis GO:0050767 158 0.011
dorsal ventral axis specification GO:0009950 66 0.011
muscle structure development GO:0061061 224 0.011
regulation of defense response GO:0031347 102 0.011
histone modification GO:0016570 106 0.011
gland morphogenesis GO:0022612 145 0.011
regulation of developmental growth GO:0048638 174 0.011
gene silencing GO:0016458 138 0.011
nucleotide metabolic process GO:0009117 161 0.011
mitotic spindle organization GO:0007052 220 0.011
regulation of molecular function GO:0065009 217 0.011
regulation of cell differentiation GO:0045595 302 0.011
female meiosis chromosome segregation GO:0016321 33 0.011
phagocytosis GO:0006909 215 0.011
ribonucleotide catabolic process GO:0009261 109 0.011
nucleoside triphosphate metabolic process GO:0009141 120 0.011
covalent chromatin modification GO:0016569 106 0.011
purine containing compound catabolic process GO:0072523 112 0.011
regulation of immune system process GO:0002682 176 0.011
defense response to gram negative bacterium GO:0050829 94 0.010
macromolecular complex assembly GO:0065003 256 0.010
cellular component assembly involved in morphogenesis GO:0010927 151 0.010
chromatin remodeling GO:0006338 72 0.010
actin polymerization or depolymerization GO:0008154 31 0.010
establishment of localization in cell GO:0051649 402 0.010
forebrain development GO:0030900 2 0.010
regulation of anatomical structure size GO:0090066 163 0.010
nucleosome organization GO:0034728 59 0.010
sensory perception of pain GO:0019233 4 0.010
negative regulation of cell differentiation GO:0045596 143 0.010
positive regulation of catabolic process GO:0009896 105 0.010
protein polymerization GO:0051258 42 0.010
purine containing compound metabolic process GO:0072521 155 0.010
meiotic chromosome separation GO:0051307 8 0.010
glial cell migration GO:0008347 31 0.010

Ercc1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

Disease DO term ID Size Probability Func Analog Org
cancer DOID:162 0 0.035
disease of cellular proliferation DOID:14566 0 0.035
organ system cancer DOID:0050686 0 0.030
disease of anatomical entity DOID:7 0 0.011