Drosophila melanogaster

96 known processes

klhl10 (Dmel_CG12423)

CG12423 gene product from transcript CG12423-RB

(Aliases: CG12423,Dmel\CG12423,anon-WO0140519.152)

klhl10 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
spermatid development GO:0007286 98 0.072
catabolic process GO:0009056 409 0.049
spermatid differentiation GO:0048515 114 0.048
positive regulation of nucleobase containing compound metabolic process GO:0045935 332 0.045
regulation of protein metabolic process GO:0051246 256 0.044
response to biotic stimulus GO:0009607 294 0.043
dna metabolic process GO:0006259 227 0.043
protein maturation GO:0051604 71 0.043
negative regulation of gene expression GO:0010629 387 0.042
protein modification process GO:0036211 438 0.042
cellular catabolic process GO:0044248 372 0.041
appendage morphogenesis GO:0035107 397 0.040
response to external biotic stimulus GO:0043207 293 0.040
activation of cysteine type endopeptidase activity GO:0097202 17 0.038
response to abiotic stimulus GO:0009628 341 0.038
programmed cell death GO:0012501 257 0.038
negative regulation of cellular metabolic process GO:0031324 382 0.037
oxoacid metabolic process GO:0043436 103 0.037
positive regulation of response to stimulus GO:0048584 323 0.037
positive regulation of macromolecule metabolic process GO:0010604 405 0.037
chromatin remodeling GO:0006338 72 0.036
cellularization GO:0007349 90 0.035
synaptic transmission GO:0007268 288 0.035
Fly
organonitrogen compound metabolic process GO:1901564 318 0.035
cellular protein modification process GO:0006464 438 0.035
negative regulation of response to stimulus GO:0048585 258 0.035
immune response GO:0006955 246 0.033
male gamete generation GO:0048232 201 0.033
wing disc morphogenesis GO:0007472 344 0.033
regulation of catabolic process GO:0009894 170 0.033
chromosome organization GO:0051276 360 0.032
body morphogenesis GO:0010171 2 0.032
organic acid metabolic process GO:0006082 103 0.032
proteolysis GO:0006508 192 0.032
death GO:0016265 284 0.031
organic substance catabolic process GO:1901575 308 0.031
regulation of cell cycle GO:0051726 291 0.031
defense response GO:0006952 300 0.031
positive regulation of proteolysis GO:0045862 52 0.031
cell death GO:0008219 279 0.031
response to other organism GO:0051707 293 0.031
developmental programmed cell death GO:0010623 138 0.031
regulation of proteolysis GO:0030162 87 0.030
negative regulation of nitrogen compound metabolic process GO:0051172 265 0.030
eye morphogenesis GO:0048592 260 0.030
single organism catabolic process GO:0044712 228 0.029
regulation of cellular protein metabolic process GO:0032268 243 0.029
immune system process GO:0002376 347 0.029
regulation of localization GO:0032879 275 0.029
positive regulation of peptidase activity GO:0010952 29 0.028
regulation of cell cycle phase transition GO:1901987 130 0.028
carboxylic acid metabolic process GO:0019752 92 0.028
protein processing GO:0016485 68 0.027
epithelial cell differentiation GO:0030855 322 0.027
imaginal disc derived wing morphogenesis GO:0007476 337 0.027
regulation of molecular function GO:0065009 217 0.027
very long chain fatty acid metabolic process GO:0000038 4 0.027
humoral immune response GO:0006959 117 0.027
mitotic spindle organization GO:0007052 220 0.027
positive regulation of signal transduction GO:0009967 223 0.027
compound eye development GO:0048749 307 0.026
vesicle mediated transport GO:0016192 381 0.026
Fly
negative regulation of cell communication GO:0010648 223 0.025
appendage development GO:0048736 401 0.025
regulation of cell cycle process GO:0010564 181 0.025
positive regulation of cysteine type endopeptidase activity GO:2001056 24 0.025
antimicrobial humoral response GO:0019730 99 0.024
phosphorylation GO:0016310 294 0.024
regulation of catalytic activity GO:0050790 185 0.024
positive regulation of endopeptidase activity GO:0010950 26 0.024
regulation of cellular catabolic process GO:0031329 157 0.024
regulation of cell death GO:0010941 173 0.024
lateral inhibition GO:0046331 206 0.024
wnt signaling pathway GO:0016055 98 0.024
protein modification by small protein conjugation or removal GO:0070647 106 0.024
segmentation GO:0035282 207 0.024
positive regulation of signaling GO:0023056 243 0.023
positive regulation of nitrogen compound metabolic process GO:0051173 354 0.023
regulation of hydrolase activity GO:0051336 97 0.023
intracellular signal transduction GO:0035556 300 0.023
tissue morphogenesis GO:0048729 297 0.023
mrna metabolic process GO:0016071 124 0.023
regulation of mitotic cell cycle GO:0007346 190 0.023
regulation of intracellular signal transduction GO:1902531 236 0.023
cell cell signaling involved in cell fate commitment GO:0045168 210 0.023
compound eye morphogenesis GO:0001745 249 0.023
small molecule metabolic process GO:0044281 305 0.022
response to bacterium GO:0009617 198 0.022
cytoskeleton dependent cytokinesis GO:0061640 81 0.022
positive regulation of cell communication GO:0010647 250 0.022
sperm individualization GO:0007291 48 0.022
positive regulation of cellular biosynthetic process GO:0031328 316 0.022
organic substance transport GO:0071702 257 0.022
imaginal disc derived appendage morphogenesis GO:0035114 395 0.022
regulation of cell differentiation GO:0045595 302 0.022
cell cycle checkpoint GO:0000075 95 0.022
macromolecule catabolic process GO:0009057 161 0.021
regulation of multicellular organismal development GO:2000026 414 0.021
monocarboxylic acid transport GO:0015718 3 0.021
modification dependent macromolecule catabolic process GO:0043632 79 0.021
negative regulation of macromolecule biosynthetic process GO:0010558 270 0.020
cell division GO:0051301 248 0.020
organelle fission GO:0048285 340 0.020
growth GO:0040007 359 0.020
Fly
homeostatic process GO:0042592 199 0.020
columnar cuboidal epithelial cell development GO:0002066 249 0.020
sleep GO:0030431 49 0.020
protein localization GO:0008104 284 0.020
positive regulation of gene expression GO:0010628 290 0.020
neurological system process GO:0050877 358 0.020
negative regulation of signal transduction GO:0009968 206 0.020
regulation of wnt signaling pathway GO:0030111 68 0.020
modification dependent protein catabolic process GO:0019941 78 0.020
positive regulation of nucleic acid templated transcription GO:1903508 266 0.019
negative regulation of nucleobase containing compound metabolic process GO:0045934 261 0.019
response to lipopolysaccharide GO:0032496 4 0.019
cytoplasmic transport GO:0016482 130 0.019
regulation of cellular protein catabolic process GO:1903362 44 0.019
defense response to other organism GO:0098542 225 0.019
post embryonic appendage morphogenesis GO:0035120 385 0.019
spermatogenesis GO:0007283 200 0.019
establishment of localization in cell GO:0051649 402 0.019
negative regulation of cellular macromolecule biosynthetic process GO:2000113 267 0.019
actin filament based process GO:0030029 220 0.019
positive regulation of rna metabolic process GO:0051254 271 0.019
single organism biosynthetic process GO:0044711 206 0.019
ubiquitin dependent protein catabolic process GO:0006511 78 0.019
negative regulation of signaling GO:0023057 219 0.019
dna packaging GO:0006323 91 0.019
spindle organization GO:0007051 253 0.019
gland morphogenesis GO:0022612 145 0.018
regulation of developmental growth GO:0048638 174 0.018
negative regulation of cell cycle GO:0045786 116 0.018
carbohydrate derivative metabolic process GO:1901135 217 0.018
protein catabolic process GO:0030163 101 0.018
nuclear division GO:0000280 332 0.018
forebrain development GO:0030900 2 0.018
sensory perception GO:0007600 196 0.018
regulation of programmed cell death GO:0043067 152 0.018
imaginal disc derived appendage development GO:0048737 399 0.018
single organism behavior GO:0044708 391 0.018
regulation of apoptotic process GO:0042981 130 0.018
salivary gland morphogenesis GO:0007435 145 0.018
regulation of multi organism process GO:0043900 131 0.018
sister chromatid segregation GO:0000819 92 0.018
nucleosome organization GO:0034728 59 0.017
positive regulation of molecular function GO:0044093 136 0.017
positive regulation of rna biosynthetic process GO:1902680 266 0.017
negative regulation of cell cycle phase transition GO:1901988 103 0.017
transcription from rna polymerase ii promoter GO:0006366 368 0.017
nucleobase containing small molecule metabolic process GO:0055086 174 0.017
regulation of behavior GO:0050795 75 0.017
purine ribonucleotide metabolic process GO:0009150 145 0.017
regulation of cellular amine metabolic process GO:0033238 3 0.017
hormone catabolic process GO:0042447 3 0.017
regulation of cellular ketone metabolic process GO:0010565 3 0.017
cellular macromolecule catabolic process GO:0044265 136 0.017
positive regulation of transcription dna templated GO:0045893 266 0.017
mitotic cell cycle checkpoint GO:0007093 88 0.017
positive regulation of catalytic activity GO:0043085 118 0.017
salivary gland development GO:0007431 162 0.017
epithelial cell development GO:0002064 274 0.017
regulation of cellular localization GO:0060341 136 0.017
microtubule organizing center organization GO:0031023 168 0.017
mitotic sister chromatid segregation GO:0000070 87 0.016
developmental maturation GO:0021700 172 0.016
chromatin organization GO:0006325 207 0.016
columnar cuboidal epithelial cell differentiation GO:0002065 256 0.016
single organism intracellular transport GO:1902582 207 0.016
oxidation reduction process GO:0055114 123 0.016
negative regulation of protein metabolic process GO:0051248 85 0.016
positive regulation of catabolic process GO:0009896 105 0.016
mitotic cytokinesis GO:0000281 50 0.016
eye development GO:0001654 323 0.016
heterocycle catabolic process GO:0046700 166 0.016
cell cycle phase transition GO:0044770 140 0.016
establishment of protein localization GO:0045184 163 0.016
positive regulation of hydrolase activity GO:0051345 78 0.016
gland development GO:0048732 191 0.016
positive regulation of intracellular signal transduction GO:1902533 116 0.016
regulation of transport GO:0051049 181 0.016
regulation of response to stress GO:0080134 200 0.016
apoptotic process GO:0006915 159 0.015
protein transport GO:0015031 155 0.015
nucleus organization GO:0006997 45 0.015
regulation of endopeptidase activity GO:0052548 36 0.015
regulation of defense response GO:0031347 102 0.015
regulation of growth GO:0040008 233 0.015
negative regulation of cellular biosynthetic process GO:0031327 277 0.015
response to organic substance GO:0010033 284 0.015
negative regulation of cellular component organization GO:0051129 108 0.015
nucleobase containing compound catabolic process GO:0034655 165 0.015
ras protein signal transduction GO:0007265 88 0.015
endocytosis GO:0006897 310 0.015
Fly
circadian sleep wake cycle GO:0042745 28 0.015
proteolysis involved in cellular protein catabolic process GO:0051603 83 0.015
protein complex biogenesis GO:0070271 201 0.015
positive regulation of biosynthetic process GO:0009891 316 0.015
regulation of organelle organization GO:0033043 196 0.015
cytokinesis GO:0000910 90 0.015
organic cyclic compound catabolic process GO:1901361 168 0.014
cellular protein catabolic process GO:0044257 83 0.014
circadian sleep wake cycle sleep GO:0050802 23 0.014
atp dependent chromatin remodeling GO:0043044 22 0.014
cellular nitrogen compound catabolic process GO:0044270 165 0.014
taxis GO:0042330 304 0.014
axon development GO:0061564 297 0.014
activation of cysteine type endopeptidase activity involved in apoptotic process GO:0006919 16 0.014
regulation of cell development GO:0060284 215 0.014
sensory organ morphogenesis GO:0090596 260 0.014
salivary gland cell autophagic cell death GO:0035071 83 0.014
macromolecular complex assembly GO:0065003 256 0.014
cellular response to dna damage stimulus GO:0006974 223 0.014
negative regulation of biosynthetic process GO:0009890 277 0.014
response to organophosphorus GO:0046683 2 0.014
rna processing GO:0006396 147 0.014
dna conformation change GO:0071103 105 0.014
ribonucleotide metabolic process GO:0009259 145 0.014
membrane organization GO:0061024 112 0.014
axonogenesis GO:0007409 290 0.014
regulation of cell division GO:0051302 72 0.014
photoreceptor cell differentiation GO:0046530 170 0.014
positive regulation of phosphorus metabolic process GO:0010562 139 0.014
small gtpase mediated signal transduction GO:0007264 88 0.014
cholesterol homeostasis GO:0042632 3 0.014
chromatin modification GO:0016568 147 0.014
spindle assembly GO:0051225 80 0.014
axis specification GO:0009798 167 0.013
defense response to bacterium GO:0042742 178 0.013
purine containing compound metabolic process GO:0072521 155 0.013
mitotic nuclear division GO:0007067 213 0.013
negative regulation of cellular protein metabolic process GO:0032269 85 0.013
histolysis GO:0007559 102 0.013
negative regulation of mitotic cell cycle phase transition GO:1901991 103 0.013
maintenance of location GO:0051235 73 0.013
glycosyl compound metabolic process GO:1901657 127 0.013
regulation of proteolysis involved in cellular protein catabolic process GO:1903050 44 0.013
purine nucleotide metabolic process GO:0006163 146 0.013
nucleotide metabolic process GO:0009117 161 0.013
response to oxygen containing compound GO:1901700 200 0.013
centrosome duplication GO:0051298 121 0.013
anion homeostasis GO:0055081 3 0.013
respiratory system development GO:0060541 213 0.013
cell proliferation GO:0008283 299 0.013
centrosome organization GO:0051297 163 0.013
regulation of protein catabolic process GO:0042176 55 0.013
negative regulation of rna biosynthetic process GO:1902679 240 0.013
blastoderm segmentation GO:0007350 159 0.013
embryonic axis specification GO:0000578 107 0.013
ovarian follicle cell development GO:0030707 248 0.013
phagocytosis GO:0006909 215 0.013
Fly
response to glucose GO:0009749 2 0.013
peptide metabolic process GO:0006518 80 0.013
acid secretion GO:0046717 1 0.013
positive regulation of apoptotic signaling pathway GO:2001235 4 0.013
salivary gland histolysis GO:0035070 88 0.013
kidney development GO:0001822 3 0.013
transmembrane transport GO:0055085 139 0.013
negative regulation of nucleic acid templated transcription GO:1903507 240 0.013
purine nucleoside metabolic process GO:0042278 127 0.013
purine ribonucleoside triphosphate metabolic process GO:0009205 119 0.013
regionalization GO:0003002 416 0.013
cellular component assembly involved in morphogenesis GO:0010927 151 0.013
ribonucleoside metabolic process GO:0009119 127 0.012
cellular amino acid metabolic process GO:0006520 61 0.012
exocrine system development GO:0035272 162 0.012
amine metabolic process GO:0009308 12 0.012
histone exchange GO:0043486 21 0.012
ion transport GO:0006811 145 0.012
regulation of anatomical structure morphogenesis GO:0022603 242 0.012
response to hexose GO:0009746 3 0.012
multicellular organismal aging GO:0010259 140 0.012
purine nucleoside triphosphate metabolic process GO:0009144 119 0.012
response to radiation GO:0009314 155 0.012
regulation of cellular amino acid metabolic process GO:0006521 0 0.012
response to wounding GO:0009611 94 0.012
autophagic cell death GO:0048102 83 0.012
cellular response to chemical stimulus GO:0070887 199 0.012
negative regulation of rna metabolic process GO:0051253 251 0.012
regulation of phosphate metabolic process GO:0019220 210 0.012
centrosome cycle GO:0007098 137 0.012
defense response to gram negative bacterium GO:0050829 94 0.012
regulation of anatomical structure size GO:0090066 163 0.012
cation transport GO:0006812 110 0.012
intracellular transport GO:0046907 228 0.012
proteasomal protein catabolic process GO:0010498 59 0.012
cell maturation GO:0048469 144 0.012
purine nucleoside triphosphate catabolic process GO:0009146 108 0.012
regulation of mapk cascade GO:0043408 92 0.012
positive regulation of macromolecule biosynthetic process GO:0010557 283 0.012
endomembrane system organization GO:0010256 119 0.012
regulation of immune response GO:0050776 118 0.012
response to monosaccharide GO:0034284 4 0.012
fatty acid elongation GO:0030497 3 0.012
protein complex assembly GO:0006461 200 0.012
protein modification by small protein conjugation GO:0032446 79 0.012
mrna processing GO:0006397 104 0.012
organophosphate metabolic process GO:0019637 195 0.012
organonitrogen compound catabolic process GO:1901565 128 0.012
regulation of mitotic sister chromatid segregation GO:0033047 28 0.012
negative regulation of developmental process GO:0051093 201 0.011
protein dna complex subunit organization GO:0071824 86 0.011
chemotaxis GO:0006935 249 0.011
single organism cellular localization GO:1902580 180 0.011
circadian sleep wake cycle process GO:0022410 24 0.011
carbohydrate metabolic process GO:0005975 82 0.011
chromosome separation GO:0051304 42 0.011
regulation of ras protein signal transduction GO:0046578 93 0.011
nucleoside triphosphate metabolic process GO:0009141 120 0.011
protein phosphorylation GO:0006468 169 0.011
detection of stimulus GO:0051606 156 0.011
response to organic cyclic compound GO:0014070 89 0.011
tissue death GO:0016271 102 0.011
negative regulation of wnt signaling pathway GO:0030178 28 0.011
negative regulation of mitotic cell cycle GO:0045930 109 0.011
positive regulation of cellular protein metabolic process GO:0032270 118 0.011
positive regulation of cellular catabolic process GO:0031331 95 0.011
photoreceptor cell development GO:0042461 96 0.011
aromatic compound catabolic process GO:0019439 166 0.011
eggshell formation GO:0030703 105 0.011
neuron projection guidance GO:0097485 241 0.011
embryonic pattern specification GO:0009880 174 0.011
very long chain fatty acid biosynthetic process GO:0042761 2 0.011
regulation of phosphorylation GO:0042325 147 0.011
regulation of mitotic cell cycle phase transition GO:1901990 130 0.011
cellular macromolecule localization GO:0070727 220 0.011
telencephalon development GO:0021537 2 0.011
chemical homeostasis GO:0048878 92 0.011
nucleoside phosphate metabolic process GO:0006753 162 0.011
positive regulation of multicellular organismal process GO:0051240 143 0.011
negative regulation of cellular catabolic process GO:0031330 34 0.011
nucleoside catabolic process GO:0009164 112 0.011
cytoskeleton dependent intracellular transport GO:0030705 44 0.011
regulation of nuclear division GO:0051783 58 0.011
posttranscriptional regulation of gene expression GO:0010608 145 0.011
response to nutrient levels GO:0031667 114 0.011
protein ubiquitination GO:0016567 70 0.011
xenobiotic catabolic process GO:0042178 1 0.011
positive regulation of transcription from rna polymerase ii promoter GO:0045944 204 0.011
regulation of chromosome segregation GO:0051983 32 0.011
intracellular mrna localization GO:0008298 66 0.011
regulation of proteasomal ubiquitin dependent protein catabolic process GO:0032434 37 0.011
dorsal ventral pattern formation GO:0009953 133 0.011
mitochondrion organization GO:0007005 65 0.011
regulation of phosphorus metabolic process GO:0051174 210 0.011
negative regulation of cell differentiation GO:0045596 143 0.011
drinking behavior GO:0042756 2 0.010
autophagy GO:0006914 108 0.010
cellular response to biotic stimulus GO:0071216 4 0.010
nucleoside metabolic process GO:0009116 127 0.010
intracellular protein transport GO:0006886 104 0.010
connective tissue development GO:0061448 3 0.010
positive regulation of phosphate metabolic process GO:0045937 139 0.010
sterol homeostasis GO:0055092 4 0.010
cellular protein localization GO:0034613 160 0.010
purine ribonucleoside metabolic process GO:0046128 127 0.010
rna localization GO:0006403 115 0.010
regulation of mitotic metaphase anaphase transition GO:0030071 26 0.010
positive regulation of cellular amine metabolic process GO:0033240 0 0.010
rrna processing GO:0006364 3 0.010
positive regulation of transport GO:0051050 92 0.010
regulation of chromosome organization GO:0033044 64 0.010
tripartite regional subdivision GO:0007351 103 0.010
positive regulation of defense response GO:0031349 59 0.010
mitotic cell cycle phase transition GO:0044772 138 0.010
organelle fusion GO:0048284 46 0.010
organ growth GO:0035265 56 0.010
embryo development ending in birth or egg hatching GO:0009792 152 0.010
single organism membrane organization GO:0044802 93 0.010
eye photoreceptor cell differentiation GO:0001754 145 0.010

klhl10 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.042
nervous system disease DOID:863 0 0.018
disease of metabolism DOID:0014667 0 0.014
inherited metabolic disorder DOID:655 0 0.014
musculoskeletal system disease DOID:17 0 0.011