Drosophila melanogaster

35 known processes

vari (Dmel_CG9326)

varicose

(Aliases: l(2)03953,38E.21,l(2)38EFa,szar,Dmel\CG9326,l(2)03953b,CG9326,Vari)

vari biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
open tracheal system development GO:0007424 204 0.997
regulation of tube size open tracheal system GO:0035151 43 0.997
regulation of tube architecture open tracheal system GO:0035152 68 0.992
branching involved in open tracheal system development GO:0060446 45 0.986
regulation of tube length open tracheal system GO:0035159 24 0.979
respiratory system development GO:0060541 213 0.892
regulation of tube size GO:0035150 46 0.887
regulation of tube diameter open tracheal system GO:0035158 11 0.735
tube development GO:0035295 244 0.624
taxis GO:0042330 304 0.483
regulation of anatomical structure size GO:0090066 163 0.390
tube morphogenesis GO:0035239 191 0.377
sensory organ morphogenesis GO:0090596 260 0.362
regulation of response to stress GO:0080134 200 0.322
imaginal disc derived appendage morphogenesis GO:0035114 395 0.318
cell cell junction organization GO:0045216 55 0.291
cuticle development GO:0042335 86 0.269
tracheal outgrowth open tracheal system GO:0007426 18 0.265
morphogenesis of an epithelium GO:0002009 276 0.260
terminal branching open tracheal system GO:0007430 17 0.241
tube fusion GO:0035146 17 0.240
morphogenesis of a branching structure GO:0001763 45 0.239
eye morphogenesis GO:0048592 260 0.234
cell division GO:0051301 248 0.226
single organism behavior GO:0044708 391 0.221
cell junction assembly GO:0034329 42 0.203
tissue morphogenesis GO:0048729 297 0.193
trachea development GO:0060438 29 0.182
branching morphogenesis of an epithelial tube GO:0048754 45 0.175
morphogenesis of a branching epithelium GO:0061138 45 0.174
apical junction assembly GO:0043297 32 0.171
compound eye development GO:0048749 307 0.163
embryo development ending in birth or egg hatching GO:0009792 152 0.162
chitin based cuticle development GO:0040003 49 0.151
cell junction organization GO:0034330 57 0.149
defense response to other organism GO:0098542 225 0.140
response to light stimulus GO:0009416 124 0.140
embryonic morphogenesis GO:0048598 206 0.131
regulation of multicellular organismal development GO:2000026 414 0.127
establishment of blood brain barrier GO:0060856 16 0.123
developmental growth involved in morphogenesis GO:0060560 65 0.120
cellular component assembly involved in morphogenesis GO:0010927 151 0.118
cell cell junction assembly GO:0007043 38 0.116
locomotory behavior GO:0007626 176 0.112
spiracle morphogenesis open tracheal system GO:0035277 22 0.105
organelle assembly GO:0070925 198 0.104
gene silencing GO:0016458 138 0.103
amino sugar metabolic process GO:0006040 10 0.102
post embryonic appendage morphogenesis GO:0035120 385 0.094
imaginal disc derived wing morphogenesis GO:0007476 337 0.092
wing disc morphogenesis GO:0007472 344 0.089
larval development GO:0002164 104 0.089
aminoglycan biosynthetic process GO:0006023 11 0.089
embryonic pattern specification GO:0009880 174 0.088
regulation of defense response GO:0031347 102 0.087
embryonic development via the syncytial blastoderm GO:0001700 148 0.083
cell recognition GO:0008037 102 0.082
cellular response to organic substance GO:0071310 132 0.082
positive regulation of macromolecule metabolic process GO:0010604 405 0.082
cellular response to molecule of bacterial origin GO:0071219 3 0.082
establishment of protein localization GO:0045184 163 0.081
branch fusion open tracheal system GO:0035147 17 0.081
cell cell signaling involved in cell fate commitment GO:0045168 210 0.080
positive regulation of catalytic activity GO:0043085 118 0.074
intracellular signal transduction GO:0035556 300 0.073
positive regulation of signal transduction GO:0009967 223 0.073
regulation of epithelial cell migration open tracheal system GO:2000274 11 0.072
catabolic process GO:0009056 409 0.072
spindle assembly GO:0051225 80 0.069
biological adhesion GO:0022610 138 0.066
morphogenesis of embryonic epithelium GO:0016331 94 0.066
positive regulation of response to stimulus GO:0048584 323 0.065
negative regulation of immune system process GO:0002683 50 0.063
dna metabolic process GO:0006259 227 0.063
extracellular matrix disassembly GO:0022617 4 0.063
macromolecular complex assembly GO:0065003 256 0.062
cell death GO:0008219 279 0.061
negative regulation of signal transduction GO:0009968 206 0.059
epithelial tube morphogenesis GO:0060562 88 0.058
compound eye photoreceptor cell differentiation GO:0001751 140 0.058
programmed cell death GO:0012501 257 0.056
defense response GO:0006952 300 0.056
regulation of cell development GO:0060284 215 0.054
localization of cell GO:0051674 257 0.053
aromatic compound catabolic process GO:0019439 166 0.052
regulation of innate immune response GO:0045088 71 0.052
regulation of gene expression epigenetic GO:0040029 128 0.051
salivary gland development GO:0007431 162 0.051
appendage morphogenesis GO:0035107 397 0.050
regulation of protein kinase activity GO:0045859 51 0.050
single organism cell adhesion GO:0098602 47 0.049
single organism biosynthetic process GO:0044711 206 0.049
hindgut development GO:0061525 58 0.049
response to abiotic stimulus GO:0009628 341 0.048
muscle organ development GO:0007517 127 0.048
regulation of protein complex disassembly GO:0043244 29 0.048
regulation of cell morphogenesis GO:0022604 163 0.046
protein processing GO:0016485 68 0.045
apoptotic process GO:0006915 159 0.045
dorsal closure GO:0007391 79 0.044
regulation of immune system process GO:0002682 176 0.044
compound eye morphogenesis GO:0001745 249 0.044
response to biotic stimulus GO:0009607 294 0.043
cellular macromolecular complex assembly GO:0034622 153 0.042
posttranscriptional regulation of gene expression GO:0010608 145 0.042
fluid transport GO:0042044 19 0.042
regulation of localization GO:0032879 275 0.042
cuticle pattern formation GO:0035017 27 0.041
neurological system process GO:0050877 358 0.041
regulation of tube diameter GO:0035296 14 0.040
regulation of extracellular matrix organization GO:1903053 4 0.040
positive regulation of immune response GO:0050778 63 0.040
response to bacterium GO:0009617 198 0.040
protein modification process GO:0036211 438 0.040
dorsal trunk growth open tracheal system GO:0035001 7 0.039
spindle organization GO:0007051 253 0.038
regulation of microtubule polymerization or depolymerization GO:0031110 27 0.038
gland development GO:0048732 191 0.038
regulation of catalytic activity GO:0050790 185 0.038
regulation of molecular function GO:0065009 217 0.038
cellular nitrogen compound catabolic process GO:0044270 165 0.037
eye development GO:0001654 323 0.037
segment specification GO:0007379 33 0.037
imaginal disc derived appendage development GO:0048737 399 0.036
negative regulation of cellular metabolic process GO:0031324 382 0.036
r7 cell differentiation GO:0045466 43 0.036
epithelial cell migration open tracheal system GO:0007427 32 0.035
organic cyclic compound catabolic process GO:1901361 168 0.035
muscle structure development GO:0061061 224 0.035
eye photoreceptor cell differentiation GO:0001754 145 0.034
chemotaxis GO:0006935 249 0.034
molting cycle chitin based cuticle GO:0007591 56 0.034
photoreceptor cell differentiation GO:0046530 170 0.033
segmentation GO:0035282 207 0.033
neuron projection guidance GO:0097485 241 0.033
dna repair GO:0006281 54 0.033
protein complex assembly GO:0006461 200 0.032
cellular protein modification process GO:0006464 438 0.032
circadian rhythm GO:0007623 105 0.032
eye photoreceptor cell development GO:0042462 81 0.032
regulation of neuron differentiation GO:0045664 103 0.032
trachea morphogenesis GO:0060439 22 0.032
establishment or maintenance of cytoskeleton polarity GO:0030952 44 0.032
response to radiation GO:0009314 155 0.031
positive regulation of multicellular organismal process GO:0051240 143 0.031
response to other organism GO:0051707 293 0.030
nucleobase containing compound catabolic process GO:0034655 165 0.030
protein phosphorylation GO:0006468 169 0.030
epithelial cell type specification open tracheal system GO:0035153 11 0.030
cellular macromolecule catabolic process GO:0044265 136 0.030
proteoglycan biosynthetic process GO:0030166 10 0.029
negative regulation of smoothened signaling pathway GO:0045879 16 0.029
negative regulation of cellular component organization GO:0051129 108 0.029
regulation of proteolysis GO:0030162 87 0.028
positive regulation of phosphorylation GO:0042327 87 0.028
protein modification by small protein conjugation or removal GO:0070647 106 0.028
regulation of epithelial cell proliferation GO:0050678 4 0.028
body morphogenesis GO:0010171 2 0.028
cellular component disassembly GO:0022411 46 0.028
positive regulation of molecular function GO:0044093 136 0.027
glucosamine containing compound metabolic process GO:1901071 9 0.027
cellular protein localization GO:0034613 160 0.027
positive regulation of response to wounding GO:1903036 15 0.027
organic substance transport GO:0071702 257 0.027
organ induction GO:0001759 3 0.027
organonitrogen compound metabolic process GO:1901564 318 0.027
macromolecule catabolic process GO:0009057 161 0.026
regulation of behavior GO:0050795 75 0.026
carbohydrate derivative biosynthetic process GO:1901137 85 0.026
carbohydrate derivative metabolic process GO:1901135 217 0.026
negative regulation of cell differentiation GO:0045596 143 0.026
axon extension GO:0048675 32 0.026
muscle cell development GO:0055001 50 0.026
regulation of cellular protein metabolic process GO:0032268 243 0.026
lumen formation open tracheal system GO:0035149 12 0.026
microtubule cytoskeleton organization involved in mitosis GO:1902850 52 0.026
kidney development GO:0001822 3 0.026
proteolysis GO:0006508 192 0.025
growth GO:0040007 359 0.025
positive regulation of signaling GO:0023056 243 0.025
regulation of cell differentiation GO:0045595 302 0.025
negative regulation of response to stimulus GO:0048585 258 0.025
positive regulation of cell communication GO:0010647 250 0.025
protein complex biogenesis GO:0070271 201 0.025
negative regulation of mitotic cell cycle GO:0045930 109 0.025
innate immune response GO:0045087 144 0.025
regulation of catabolic process GO:0009894 170 0.024
nuclear transport GO:0051169 72 0.024
salivary gland morphogenesis GO:0007435 145 0.024
death GO:0016265 284 0.024
regulation of neurogenesis GO:0050767 158 0.024
kidney epithelium development GO:0072073 3 0.024
secondary metabolic process GO:0019748 75 0.024
regulation of decapentaplegic signaling pathway GO:0090097 8 0.024
imaginal disc derived wing margin morphogenesis GO:0008587 41 0.023
germarium derived egg chamber formation GO:0007293 101 0.023
circulatory system development GO:0072359 82 0.023
negative regulation of rna metabolic process GO:0051253 251 0.023
positive regulation of protein metabolic process GO:0051247 128 0.023
adult somatic muscle development GO:0007527 14 0.022
ribose phosphate metabolic process GO:0019693 145 0.022
regulation of protein metabolic process GO:0051246 256 0.022
oxoacid metabolic process GO:0043436 103 0.022
regulation of anatomical structure morphogenesis GO:0022603 242 0.022
nuclear division GO:0000280 332 0.022
protein maturation GO:0051604 71 0.022
chitin based cuticle sclerotization GO:0007593 19 0.022
meiotic cell cycle GO:0051321 171 0.022
positive regulation of defense response GO:0031349 59 0.022
immune system process GO:0002376 347 0.022
cellular response to lipopolysaccharide GO:0071222 3 0.021
mapk cascade GO:0000165 107 0.021
defense response to bacterium GO:0042742 178 0.021
zymogen activation GO:0031638 20 0.021
organic substance catabolic process GO:1901575 308 0.021
phosphorylation GO:0016310 294 0.021
purine ribonucleoside triphosphate catabolic process GO:0009207 108 0.021
extracellular structure organization GO:0043062 46 0.021
microtubule polymerization or depolymerization GO:0031109 39 0.021
protein catabolic process GO:0030163 101 0.020
regulation of cell cell adhesion GO:0022407 21 0.020
cellular protein complex assembly GO:0043623 71 0.020
positive regulation of cell development GO:0010720 61 0.020
rhythmic process GO:0048511 106 0.020
positive regulation of cellular protein metabolic process GO:0032270 118 0.020
response to external biotic stimulus GO:0043207 293 0.019
cell adhesion GO:0007155 136 0.019
negative regulation of nucleobase containing compound metabolic process GO:0045934 261 0.019
response to lipopolysaccharide GO:0032496 4 0.019
protein transport GO:0015031 155 0.019
columnar cuboidal epithelial cell development GO:0002066 249 0.019
positive regulation of intracellular signal transduction GO:1902533 116 0.018
cellular response to organic cyclic compound GO:0071407 32 0.018
cell proliferation GO:0008283 299 0.018
regulation of transcription from rna polymerase ii promoter GO:0006357 378 0.018
nucleocytoplasmic transport GO:0006913 72 0.018
reproductive system development GO:0061458 74 0.018
negative regulation of gene expression GO:0010629 387 0.018
anterior posterior axis specification embryo GO:0008595 103 0.018
smoothened signaling pathway GO:0007224 49 0.018
regulation of cell fate specification GO:0042659 27 0.017
cellular response to chemical stimulus GO:0070887 199 0.017
axon development GO:0061564 297 0.017
negative regulation of biosynthetic process GO:0009890 277 0.017
negative regulation of cell communication GO:0010648 223 0.017
compound eye cone cell differentiation GO:0042675 13 0.017
gene silencing by rna GO:0031047 57 0.017
cellular response to lipid GO:0071396 20 0.017
cellular protein catabolic process GO:0044257 83 0.017
phagocytosis GO:0006909 215 0.017
positive regulation of cell cell adhesion GO:0022409 9 0.016
regulation of intracellular signal transduction GO:1902531 236 0.016
chitin based embryonic cuticle biosynthetic process GO:0008362 16 0.016
immune response activating signal transduction GO:0002757 2 0.016
regulation of immune response GO:0050776 118 0.016
regulation of protein modification process GO:0031399 112 0.016
defense response to fungus GO:0050832 48 0.016
nucleoside triphosphate metabolic process GO:0009141 120 0.016
positive regulation of neuron differentiation GO:0045666 26 0.016
defense response to gram negative bacterium GO:0050829 94 0.016
positive regulation of protein kinase activity GO:0045860 25 0.015
signal transduction by phosphorylation GO:0023014 107 0.015
eye photoreceptor cell fate commitment GO:0042706 37 0.015
regulation of nervous system development GO:0051960 248 0.015
negative regulation of cellular protein metabolic process GO:0032269 85 0.015
anterior posterior pattern specification GO:0009952 136 0.015
sulfur compound metabolic process GO:0006790 59 0.015
single organism nuclear import GO:1902593 51 0.015
basement membrane organization GO:0071711 10 0.015
heart process GO:0003015 37 0.015
negative regulation of multi organism process GO:0043901 29 0.015
neuromuscular synaptic transmission GO:0007274 67 0.015
sensory perception GO:0007600 196 0.015
proteasomal protein catabolic process GO:0010498 59 0.015
response to wounding GO:0009611 94 0.015
cardiovascular system development GO:0072358 82 0.015
ras protein signal transduction GO:0007265 88 0.014
regulation of gene silencing GO:0060968 63 0.014
posttranscriptional gene silencing GO:0016441 46 0.014
extracellular matrix organization GO:0030198 32 0.014
actin cytoskeleton organization GO:0030036 206 0.014
negative regulation of cell cycle process GO:0010948 109 0.014
regulation of protein stability GO:0031647 43 0.014
positive regulation of immune system process GO:0002684 68 0.014
septate junction assembly GO:0019991 26 0.014
reproductive structure development GO:0048608 74 0.014
organonitrogen compound biosynthetic process GO:1901566 117 0.014
regulation of i kappab kinase nf kappab signaling GO:0043122 2 0.014
blastoderm segmentation GO:0007350 159 0.014
regulation of mapk cascade GO:0043408 92 0.013
regulation of wnt signaling pathway GO:0030111 68 0.013
purine ribonucleoside catabolic process GO:0046130 112 0.013
neuron recognition GO:0008038 101 0.013
cellular macromolecule localization GO:0070727 220 0.013
response to hypoxia GO:0001666 53 0.013
positive regulation of phosphate metabolic process GO:0045937 139 0.013
protein polymerization GO:0051258 42 0.013
developmental growth GO:0048589 280 0.013
regulation of organ formation GO:0003156 3 0.013
protein targeting to nucleus GO:0044744 51 0.013
nephron development GO:0072006 3 0.013
glial cell differentiation GO:0010001 35 0.013
establishment of glial blood brain barrier GO:0060857 14 0.013
multi organism behavior GO:0051705 175 0.013
stem cell maintenance GO:0019827 67 0.013
developmental pigmentation GO:0048066 68 0.013
developmental induction GO:0031128 3 0.013
circulatory system process GO:0003013 37 0.013
tissue death GO:0016271 102 0.013
molting cycle GO:0042303 56 0.013
action potential GO:0001508 13 0.013
positive regulation of kinase activity GO:0033674 25 0.013
transcription from rna polymerase ii promoter GO:0006366 368 0.012
regulation of axon extension involved in axon guidance GO:0048841 4 0.012
cellular catabolic process GO:0044248 372 0.012
cellular response to dna damage stimulus GO:0006974 223 0.012
heterocycle catabolic process GO:0046700 166 0.012
negative regulation of developmental process GO:0051093 201 0.012
endomembrane system organization GO:0010256 119 0.012
regulation of phosphate metabolic process GO:0019220 210 0.012
response to decreased oxygen levels GO:0036293 58 0.012
epidermal cell differentiation GO:0009913 51 0.012
regulation of microtubule cytoskeleton organization GO:0070507 41 0.012
photoreceptor cell fate commitment GO:0046552 41 0.012
positive regulation of transferase activity GO:0051347 26 0.012
mitotic spindle organization GO:0007052 220 0.012
regulation of phosphorus metabolic process GO:0051174 210 0.012
cellular response to biotic stimulus GO:0071216 4 0.012
epithelial cell development GO:0002064 274 0.012
cellular response to oxygen containing compound GO:1901701 79 0.012
myotube cell development GO:0014904 3 0.012
regulation of circadian rhythm GO:0042752 49 0.012
regulation of protein serine threonine kinase activity GO:0071900 25 0.012
immune response GO:0006955 246 0.011
centrosome organization GO:0051297 163 0.011
negative regulation of protein depolymerization GO:1901880 23 0.011
regulation of response to biotic stimulus GO:0002831 63 0.011
regulation of apoptotic process GO:0042981 130 0.011
columnar cuboidal epithelial cell differentiation GO:0002065 256 0.011
rhythmic behavior GO:0007622 76 0.011
regulation of smoothened signaling pathway GO:0008589 28 0.011
nucleotide metabolic process GO:0009117 161 0.011
positive regulation of gene expression GO:0010628 290 0.011
meiosis i GO:0007127 59 0.011
negative regulation of cell development GO:0010721 62 0.011
embryonic axis specification GO:0000578 107 0.011
chromosome segregation GO:0007059 157 0.011
negative regulation of signaling GO:0023057 219 0.011
nucleoside triphosphate catabolic process GO:0009143 108 0.011
compound eye photoreceptor development GO:0042051 78 0.011
positive regulation of cysteine type endopeptidase activity GO:2001056 24 0.011
negative regulation of protein metabolic process GO:0051248 85 0.011
gene silencing by mirna GO:0035195 22 0.011
central nervous system development GO:0007417 201 0.010
wnt signaling pathway GO:0016055 98 0.010
filtration diaphragm assembly GO:0036058 4 0.010
negative regulation of microtubule depolymerization GO:0007026 21 0.010
regulation of phosphatase activity GO:0010921 3 0.010
ribonucleotide metabolic process GO:0009259 145 0.010
eye pigmentation GO:0048069 43 0.010
reproductive behavior GO:0019098 122 0.010
regulation of kinase activity GO:0043549 53 0.010
morphogenesis of follicular epithelium GO:0016333 36 0.010
ribonucleoside triphosphate metabolic process GO:0009199 119 0.010
cell cycle phase transition GO:0044770 140 0.010
intracellular protein transport GO:0006886 104 0.010
developmental cell growth GO:0048588 52 0.010

vari disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

Disease DO term ID Size Probability Func Analog Org
cancer DOID:162 0 0.054
disease of cellular proliferation DOID:14566 0 0.054
organ system cancer DOID:0050686 0 0.054
disease of anatomical entity DOID:7 0 0.034
sensory system disease DOID:0050155 0 0.012
nervous system disease DOID:863 0 0.012