Drosophila melanogaster

64 known processes

Traf6 (Dmel_CG10961)

TNF-receptor-associated factor 6

(Aliases: TRAF2,TRAF,TRAF6,dtraf2,Traf2,dTRAF6,dTraf2,DTRAF2,Dmel\CG10961,CG10961,dTRAF2)

Traf6 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
immune system process GO:0002376 347 0.620
catabolic process GO:0009056 409 0.386
establishment of localization in cell GO:0051649 402 0.359
immune response GO:0006955 246 0.317
defense response GO:0006952 300 0.265
cellular response to extracellular stimulus GO:0031668 64 0.255
defense response to other organism GO:0098542 225 0.240
immune effector process GO:0002252 98 0.237
regulation of transport GO:0051049 181 0.232
mucosal immune response GO:0002385 10 0.230
cellular response to chemical stimulus GO:0070887 199 0.209
cytoplasmic transport GO:0016482 130 0.208
regulation of response to external stimulus GO:0032101 115 0.206
response to abiotic stimulus GO:0009628 341 0.201
response to biotic stimulus GO:0009607 294 0.196
response to external biotic stimulus GO:0043207 293 0.196
humoral immune response GO:0006959 117 0.195
negative regulation of cellular metabolic process GO:0031324 382 0.191
autophagy GO:0006914 108 0.189
regulation of immune response GO:0050776 118 0.189
regulation of multi organism process GO:0043900 131 0.187
regulation of cell death GO:0010941 173 0.182
Fly
response to other organism GO:0051707 293 0.180
cellular catabolic process GO:0044248 372 0.175
antimicrobial humoral response GO:0019730 99 0.174
histone modification GO:0016570 106 0.166
innate immune response GO:0045087 144 0.159
covalent chromatin modification GO:0016569 106 0.157
regulation of defense response GO:0031347 102 0.156
embryonic morphogenesis GO:0048598 206 0.155
Fly
negative regulation of cellular biosynthetic process GO:0031327 277 0.154
regulation of intracellular signal transduction GO:1902531 236 0.150
taxis GO:0042330 304 0.145
membrane organization GO:0061024 112 0.144
regulation of apoptotic process GO:0042981 130 0.139
Fly
regulation of immune effector process GO:0002697 52 0.132
chromatin modification GO:0016568 147 0.129
cellular protein modification process GO:0006464 438 0.129
negative regulation of nitrogen compound metabolic process GO:0051172 265 0.128
regulation of programmed cell death GO:0043067 152 0.126
Fly
aging GO:0007568 143 0.118
positive regulation of developmental process GO:0051094 143 0.117
protein localization GO:0008104 284 0.115
Fly
regulation of cellular response to stress GO:0080135 89 0.112
Fly
regulation of antimicrobial humoral response GO:0002759 50 0.108
defense response to bacterium GO:0042742 178 0.108
Fly
epithelial cell development GO:0002064 274 0.105
Fly
positive regulation of response to stimulus GO:0048584 323 0.104
Fly
positive regulation of immune response GO:0050778 63 0.100
intracellular signal transduction GO:0035556 300 0.099
striated muscle cell differentiation GO:0051146 90 0.096
epithelial cell differentiation GO:0030855 322 0.094
Fly
regulation of cell cycle GO:0051726 291 0.094
positive regulation of molecular function GO:0044093 136 0.093
negative regulation of rna biosynthetic process GO:1902679 240 0.093
nucleocytoplasmic transport GO:0006913 72 0.093
imaginal disc derived appendage development GO:0048737 399 0.093
muscle cell differentiation GO:0042692 103 0.091
regulation of molecular function GO:0065009 217 0.090
negative regulation of biosynthetic process GO:0009890 277 0.089
regulation of response to stress GO:0080134 200 0.089
cell motility GO:0048870 251 0.087
regulation of cell differentiation GO:0045595 302 0.087
digestive system development GO:0055123 149 0.086
Fly
dorsal appendage formation GO:0046843 47 0.086
histone acetylation GO:0016573 38 0.084
phosphorylation GO:0016310 294 0.084
Fly
regulation of immune system process GO:0002682 176 0.083
muscle structure development GO:0061061 224 0.083
imaginal disc derived appendage morphogenesis GO:0035114 395 0.083
positive regulation of transcription dna templated GO:0045893 266 0.079
intracellular transport GO:0046907 228 0.079
immune response activating signal transduction GO:0002757 2 0.078
defense response to virus GO:0051607 23 0.077
single organism intracellular transport GO:1902582 207 0.077
regulation of cell cycle process GO:0010564 181 0.076
response to starvation GO:0042594 97 0.075
regulation of autophagy GO:0010506 62 0.075
cellular response to nutrient levels GO:0031669 62 0.074
negative regulation of nucleobase containing compound metabolic process GO:0045934 261 0.073
regulation of nervous system development GO:0051960 248 0.073
cation transport GO:0006812 110 0.072
cellular response to starvation GO:0009267 61 0.072
cell death GO:0008219 279 0.072
programmed cell death GO:0012501 257 0.072
Fly
protein localization to organelle GO:0033365 82 0.071
dendrite morphogenesis GO:0048813 199 0.071
antimicrobial peptide production GO:0002775 46 0.070
establishment of protein localization GO:0045184 163 0.070
regulation of production of molecular mediator of immune response GO:0002700 44 0.068
stress activated mapk cascade GO:0051403 52 0.067
Fly
positive regulation of nucleic acid templated transcription GO:1903508 266 0.065
response to endogenous stimulus GO:0009719 119 0.061
endocytosis GO:0006897 310 0.061
Fly
mitotic nuclear division GO:0007067 213 0.061
regulation of anatomical structure size GO:0090066 163 0.061
morphogenesis of an epithelium GO:0002009 276 0.061
developmental programmed cell death GO:0010623 138 0.061
Fly
growth GO:0040007 359 0.061
eye development GO:0001654 323 0.060
Fly
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 65 0.059
nuclear transport GO:0051169 72 0.058
chromatin organization GO:0006325 207 0.057
positive regulation of cell proliferation GO:0008284 47 0.057
positive regulation of defense response GO:0031349 59 0.057
organic acid metabolic process GO:0006082 103 0.056
response to bacterium GO:0009617 198 0.056
Fly
regulation of cellular catabolic process GO:0031329 157 0.056
regulation of cellular component size GO:0032535 98 0.055
organic substance transport GO:0071702 257 0.055
histone h4 acetylation GO:0043967 13 0.054
positive regulation of signal transduction GO:0009967 223 0.054
Fly
single organism membrane organization GO:0044802 93 0.054
organelle membrane fusion GO:0090174 16 0.054
regulation of chromosome organization GO:0033044 64 0.052
regulation of cellular protein metabolic process GO:0032268 243 0.051
regulation of wnt signaling pathway GO:0030111 68 0.051
negative regulation of nucleic acid templated transcription GO:1903507 240 0.051
positive regulation of nucleobase containing compound metabolic process GO:0045935 332 0.051
protein transport GO:0015031 155 0.050
regulation of defense response to virus by host GO:0050691 10 0.050
enzyme linked receptor protein signaling pathway GO:0007167 179 0.050
heart process GO:0003015 37 0.050
positive regulation of catalytic activity GO:0043085 118 0.050
response to oxygen containing compound GO:1901700 200 0.049
regulation of localization GO:0032879 275 0.049
developmental pigmentation GO:0048066 68 0.049
mrna splicing via spliceosome GO:0000398 73 0.049
chemical homeostasis GO:0048878 92 0.049
rna splicing GO:0008380 83 0.049
negative regulation of cell differentiation GO:0045596 143 0.048
regulation of mitotic cell cycle GO:0007346 190 0.048
actin filament based process GO:0030029 220 0.047
Fly
chromosome organization GO:0051276 360 0.047
response to temperature stimulus GO:0009266 106 0.047
dendrite development GO:0016358 204 0.047
single fertilization GO:0007338 24 0.047
eggshell chorion assembly GO:0007306 66 0.047
immune response regulating signaling pathway GO:0002764 2 0.046
death GO:0016265 284 0.046
epithelium migration GO:0090132 148 0.045
negative regulation of apoptotic process GO:0043066 63 0.045
positive regulation of macromolecule biosynthetic process GO:0010557 283 0.045
positive regulation of autophagy GO:0010508 21 0.045
columnar cuboidal epithelial cell differentiation GO:0002065 256 0.044
response to lipopolysaccharide GO:0032496 4 0.044
response to nutrient levels GO:0031667 114 0.044
cellular response to abiotic stimulus GO:0071214 58 0.044
divalent metal ion transport GO:0070838 26 0.044
central nervous system development GO:0007417 201 0.043
negative regulation of cellular macromolecule biosynthetic process GO:2000113 267 0.042
positive regulation of transcription from rna polymerase ii promoter GO:0045944 204 0.042
positive regulation of catabolic process GO:0009896 105 0.041
cellular protein localization GO:0034613 160 0.041
positive regulation of multicellular organismal process GO:0051240 143 0.041
response to extracellular stimulus GO:0009991 116 0.041
regulation of cellular amine metabolic process GO:0033238 3 0.040
chemotaxis GO:0006935 249 0.040
intracellular protein transport GO:0006886 104 0.040
protein import into nucleus GO:0006606 51 0.040
positive regulation of transport GO:0051050 92 0.039
protein localization to nucleus GO:0034504 55 0.039
connective tissue development GO:0061448 3 0.039
organic substance catabolic process GO:1901575 308 0.039
localization of cell GO:0051674 257 0.039
negative regulation of rna metabolic process GO:0051253 251 0.039
negative regulation of programmed cell death GO:0043069 72 0.038
brain development GO:0007420 120 0.038
regulation of developmental growth GO:0048638 174 0.038
protein acylation GO:0043543 42 0.038
protein phosphorylation GO:0006468 169 0.038
peptidyl amino acid modification GO:0018193 105 0.038
positive regulation of biosynthetic process GO:0009891 316 0.038
positive regulation of jun kinase activity GO:0043507 4 0.038
homeostatic process GO:0042592 199 0.037
cation homeostasis GO:0055080 51 0.037
stem cell proliferation GO:0072089 88 0.037
activation of innate immune response GO:0002218 4 0.037
mitotic spindle organization GO:0007052 220 0.037
response to radiation GO:0009314 155 0.036
regulation of catalytic activity GO:0050790 185 0.036
regulation of humoral immune response GO:0002920 51 0.036
response to organic substance GO:0010033 284 0.036
positive regulation of cell differentiation GO:0045597 64 0.036
regulation of cell development GO:0060284 215 0.036
metal ion homeostasis GO:0055065 44 0.036
nephron development GO:0072006 3 0.036
positive regulation of response to external stimulus GO:0032103 44 0.036
regulation of cellular ketone metabolic process GO:0010565 3 0.036
negative regulation of transcription dna templated GO:0045892 237 0.035
chromatin remodeling GO:0006338 72 0.035
positive regulation of macromolecule metabolic process GO:0010604 405 0.035
regulation of ion transport GO:0043269 39 0.035
axon guidance GO:0007411 233 0.035
positive regulation of humoral immune response GO:0002922 28 0.034
phagocytosis GO:0006909 215 0.034
Fly
mrna metabolic process GO:0016071 124 0.034
positive regulation of cellular protein metabolic process GO:0032270 118 0.034
neuron projection guidance GO:0097485 241 0.034
positive regulation of rna biosynthetic process GO:1902680 266 0.034
positive regulation of cellular biosynthetic process GO:0031328 316 0.033
positive regulation of cell size GO:0045793 21 0.033
actin cytoskeleton organization GO:0030036 206 0.033
positive regulation of signaling GO:0023056 243 0.033
Fly
negative regulation of transcription from rna polymerase ii promoter GO:0000122 119 0.033
positive regulation of nitrogen compound metabolic process GO:0051173 354 0.033
regulation of phosphate metabolic process GO:0019220 210 0.032
Fly
forebrain development GO:0030900 2 0.032
regulation of small gtpase mediated signal transduction GO:0051056 93 0.032
regulation of phosphorus metabolic process GO:0051174 210 0.032
Fly
regulation of defense response to virus GO:0050688 14 0.032
apoptotic process GO:0006915 159 0.032
Fly
cell adhesion GO:0007155 136 0.032
nuclear import GO:0051170 51 0.032
negative regulation of signal transduction GO:0009968 206 0.032
production of molecular mediator of immune response GO:0002440 46 0.032
regulation of protein modification process GO:0031399 112 0.032
digestive tract development GO:0048565 149 0.031
Fly
protein targeting to nucleus GO:0044744 51 0.031
positive regulation of cell communication GO:0010647 250 0.031
Fly
negative regulation of developmental process GO:0051093 201 0.031
positive regulation of gene expression GO:0010628 290 0.031
axonogenesis GO:0007409 290 0.031
regulation of intracellular transport GO:0032386 64 0.031
regulation of mapk cascade GO:0043408 92 0.030
Fly
negative regulation of cell cycle GO:0045786 116 0.030
axon development GO:0061564 297 0.030
regulation of cytoplasmic transport GO:1903649 47 0.030
regulation of bmp signaling pathway GO:0030510 23 0.029
protein catabolic process GO:0030163 101 0.029
adult chitin containing cuticle pigmentation GO:0048085 16 0.029
gastrulation GO:0007369 70 0.029
Fly
cell cycle checkpoint GO:0000075 95 0.029
regulation of stress activated mapk cascade GO:0032872 41 0.029
Fly
response to wounding GO:0009611 94 0.029
myotube cell development GO:0014904 3 0.028
antibacterial humoral response GO:0019731 44 0.028
dorsal closure GO:0007391 79 0.028
regulation of protein metabolic process GO:0051246 256 0.028
regulation of innate immune response GO:0045088 71 0.028
cell cycle phase transition GO:0044770 140 0.028
cellular response to oxygen containing compound GO:1901701 79 0.028
regulation of transcription from rna polymerase ii promoter GO:0006357 378 0.028
protein modification process GO:0036211 438 0.028
telencephalon development GO:0021537 2 0.028
nuclear division GO:0000280 332 0.028
positive regulation of protein import into nucleus GO:0042307 21 0.028
wing disc morphogenesis GO:0007472 344 0.028
lateral inhibition GO:0046331 206 0.027
regulation of catabolic process GO:0009894 170 0.027
spermatid development GO:0007286 98 0.027
small molecule metabolic process GO:0044281 305 0.027
histolysis GO:0007559 102 0.027
Fly
cell migration GO:0016477 238 0.027
regulation of stress activated protein kinase signaling cascade GO:0070302 42 0.027
Fly
cardiocyte differentiation GO:0035051 29 0.027
head development GO:0060322 135 0.027
cellular response to organic substance GO:0071310 132 0.027
melanization defense response GO:0035006 45 0.026
regulation of cell cycle phase transition GO:1901987 130 0.026
neurological system process GO:0050877 358 0.026
ribonucleoprotein complex biogenesis GO:0022613 31 0.026
circulatory system development GO:0072359 82 0.026
cell maturation GO:0048469 144 0.026
positive regulation of protein metabolic process GO:0051247 128 0.026
antibacterial peptide production GO:0002778 22 0.026
cell proliferation GO:0008283 299 0.026
response to organophosphorus GO:0046683 2 0.026
regulation of defense response to bacterium GO:1900424 30 0.026
rna splicing via transesterification reactions with bulged adenosine as nucleophile GO:0000377 73 0.026
columnar cuboidal epithelial cell development GO:0002066 249 0.025
vesicle mediated transport GO:0016192 381 0.025
Fly
positive regulation of hydrolase activity GO:0051345 78 0.025
positive regulation of intracellular signal transduction GO:1902533 116 0.025
Fly
positive regulation of defense response to virus by host GO:0002230 10 0.025
regulation of i kappab kinase nf kappab signaling GO:0043122 2 0.025
organelle localization GO:0051640 148 0.025
response to nitrogen compound GO:1901698 90 0.025
ovarian follicle cell development GO:0030707 248 0.025
detection of stimulus GO:0051606 156 0.025
regulation of cellular amide metabolic process GO:0034248 39 0.025
regulation of cellular amino acid metabolic process GO:0006521 0 0.025
mrna processing GO:0006397 104 0.025
regulation of organelle organization GO:0033043 196 0.025
dna damage checkpoint GO:0000077 78 0.025
ion transport GO:0006811 145 0.025
cellular component assembly involved in morphogenesis GO:0010927 151 0.025
negative regulation of macromolecule biosynthetic process GO:0010558 270 0.025
organonitrogen compound metabolic process GO:1901564 318 0.025
positive regulation of protein localization to nucleus GO:1900182 21 0.024
response to alkaloid GO:0043279 26 0.024
positive regulation of protein modification process GO:0031401 58 0.024
mapk cascade GO:0000165 107 0.024
Fly
response to fungus GO:0009620 50 0.024
regulation of antimicrobial peptide biosynthetic process GO:0002805 38 0.024
regulation of biosynthetic process of antibacterial peptides active against gram positive bacteria GO:0002816 3 0.024
positive regulation of mapk cascade GO:0043410 63 0.023
Fly
positive regulation of immune effector process GO:0002699 28 0.023
negative regulation of mitotic cell cycle GO:0045930 109 0.023
negative regulation of cell cycle process GO:0010948 109 0.023
response to hydrogen peroxide GO:0042542 11 0.023
cellular response to radiation GO:0071478 52 0.023
extrinsic apoptotic signaling pathway GO:0097191 1 0.023
regulation of mitotic cell cycle phase transition GO:1901990 130 0.023
asymmetric protein localization involved in cell fate determination GO:0045167 9 0.022
Fly
larval midgut histolysis GO:0035069 22 0.022
molting cycle chitin based cuticle GO:0007591 56 0.022
carboxylic acid metabolic process GO:0019752 92 0.022
regulation of response to oxidative stress GO:1902882 4 0.022
multicellular organismal reproductive behavior GO:0033057 110 0.022
gastrulation involving germ band extension GO:0010004 36 0.022
Fly
positive regulation of phosphorus metabolic process GO:0010562 139 0.022
Fly
response to heat GO:0009408 63 0.022
regionalization GO:0003002 416 0.022
regulation of ras protein signal transduction GO:0046578 93 0.021
regulation of response to biotic stimulus GO:0002831 63 0.021
open tracheal system development GO:0007424 204 0.021
cellular lipid metabolic process GO:0044255 83 0.021
negative regulation of cell death GO:0060548 81 0.021
tissue migration GO:0090130 155 0.021
salivary gland morphogenesis GO:0007435 145 0.021
Fly
regulation of nucleocytoplasmic transport GO:0046822 35 0.021
imaginal disc derived wing morphogenesis GO:0007476 337 0.021
nephron epithelium development GO:0072009 3 0.021
post embryonic appendage morphogenesis GO:0035120 385 0.021
organ or tissue specific immune response GO:0002251 10 0.021
positive regulation of intracellular transport GO:0032388 42 0.021
cellular macromolecule localization GO:0070727 220 0.021
cellular divalent inorganic cation homeostasis GO:0072503 23 0.021
regulation of mrna metabolic process GO:1903311 72 0.020
peripheral nervous system development GO:0007422 52 0.020
gland morphogenesis GO:0022612 145 0.020
Fly
regulation of antimicrobial peptide production GO:0002784 44 0.020
response to oxidative stress GO:0006979 86 0.020
eye antennal disc development GO:0035214 60 0.020
cardiovascular system development GO:0072358 82 0.020
jnk cascade GO:0007254 50 0.020
Fly
blood circulation GO:0008015 26 0.020
positive regulation of phosphorylation GO:0042327 87 0.020
Fly
positive regulation of cell death GO:0010942 69 0.020
Fly
positive regulation of apoptotic signaling pathway GO:2001235 4 0.020
muscle organ development GO:0007517 127 0.020
metal ion transport GO:0030001 74 0.020
cuticle pigmentation GO:0048067 22 0.020
pigmentation GO:0043473 75 0.020
regulation of cell size GO:0008361 63 0.020
cellular cation homeostasis GO:0030003 38 0.020
negative regulation of cellular component organization GO:0051129 108 0.020
oxoacid metabolic process GO:0043436 103 0.020
cellular response to biotic stimulus GO:0071216 4 0.020
positive regulation of programmed cell death GO:0043068 62 0.020
Fly
response to lipid GO:0033993 38 0.020
response to organic cyclic compound GO:0014070 89 0.020
cell activation GO:0001775 9 0.020
cellular response to lipopolysaccharide GO:0071222 3 0.020
positive regulation of phosphate metabolic process GO:0045937 139 0.020
Fly
cellular nitrogen compound catabolic process GO:0044270 165 0.020
protein targeting GO:0006605 64 0.019
tube morphogenesis GO:0035239 191 0.019
Fly
negative regulation of cell communication GO:0010648 223 0.019
blastoderm segmentation GO:0007350 159 0.019
organelle assembly GO:0070925 198 0.019
respiratory system development GO:0060541 213 0.019
vesicle fusion GO:0006906 19 0.019
autophagic cell death GO:0048102 83 0.019
Fly
germ line stem cell maintenance GO:0030718 50 0.019
gland development GO:0048732 191 0.019
Fly
response to metal ion GO:0010038 23 0.019
skeletal muscle fiber development GO:0048741 3 0.019
positive regulation of ras gtpase activity GO:0032320 36 0.019
positive regulation of rna metabolic process GO:0051254 271 0.019
regulation of protein import into nucleus GO:0042306 28 0.019
macromolecular complex assembly GO:0065003 256 0.019
kidney epithelium development GO:0072073 3 0.019
antibacterial peptide biosynthetic process GO:0002780 22 0.018
response to growth factor GO:0070848 31 0.018
antimicrobial peptide biosynthetic process GO:0002777 38 0.018
regulation of developmental pigmentation GO:0048070 24 0.018
exocrine system development GO:0035272 162 0.018
Fly
negative regulation of mitotic cell cycle phase transition GO:1901991 103 0.018
cellular metal ion homeostasis GO:0006875 31 0.018
cell recognition GO:0008037 102 0.018
guanosine containing compound catabolic process GO:1901069 74 0.018
cellular response to external stimulus GO:0071496 66 0.018
positive regulation of protein transport GO:0051222 37 0.018
nephron tubule morphogenesis GO:0072078 3 0.018
cell fate determination GO:0001709 91 0.018
Fly
regulation of embryonic cell shape GO:0016476 30 0.018
ion homeostasis GO:0050801 55 0.018
tube development GO:0035295 244 0.018
Fly
positive regulation of cellular amino acid metabolic process GO:0045764 0 0.018
tissue morphogenesis GO:0048729 297 0.018
cellular amino acid metabolic process GO:0006520 61 0.018
regulation of cell division GO:0051302 72 0.018
positive regulation of antimicrobial humoral response GO:0002760 28 0.018
digestive tract morphogenesis GO:0048546 127 0.017
Fly
response to light stimulus GO:0009416 124 0.017
negative regulation of response to stimulus GO:0048585 258 0.017
positive regulation of developmental growth GO:0048639 62 0.017
macroautophagy GO:0016236 42 0.017
negative regulation of multicellular organismal process GO:0051241 142 0.017
organic hydroxy compound metabolic process GO:1901615 83 0.017
amide biosynthetic process GO:0043604 42 0.017
response to organonitrogen compound GO:0010243 75 0.017
single organism membrane fusion GO:0044801 42 0.017
rna processing GO:0006396 147 0.017
developmental maturation GO:0021700 172 0.017
ubiquitin dependent protein catabolic process GO:0006511 78 0.017
neuroblast proliferation GO:0007405 74 0.017
internal peptidyl lysine acetylation GO:0018393 38 0.017
regulation of mrna splicing via spliceosome GO:0048024 64 0.017
regulation of cellular localization GO:0060341 136 0.017
regulation of synaptic growth at neuromuscular junction GO:0008582 89 0.016
cellular amine metabolic process GO:0044106 12 0.016
peptidoglycan recognition protein signaling pathway GO:0061057 16 0.016
single organism behavior GO:0044708 391 0.016
sensory organ morphogenesis GO:0090596 260 0.016
positive regulation of growth GO:0045927 75 0.016
regulation of cell substrate adhesion GO:0010810 2 0.016
internal protein amino acid acetylation GO:0006475 38 0.016
negative regulation of signaling GO:0023057 219 0.016
ion transmembrane transport GO:0034220 122 0.016
actin filament organization GO:0007015 126 0.016
protein ubiquitination GO:0016567 70 0.016
alternative mrna splicing via spliceosome GO:0000380 60 0.016
positive regulation of cell migration GO:0030335 2 0.016
membrane depolarization GO:0051899 4 0.016
single organism catabolic process GO:0044712 228 0.016
cellular response to heat GO:0034605 24 0.016
innate immune response activating signal transduction GO:0002758 2 0.015
negative regulation of cell cycle phase transition GO:1901988 103 0.015
nephron tubule development GO:0072080 3 0.015
regulation of chromatin modification GO:1903308 28 0.015
regulation of protein catabolic process GO:0042176 55 0.015
determination of adult lifespan GO:0008340 137 0.015
spindle organization GO:0007051 253 0.015
morphogenesis of embryonic epithelium GO:0016331 94 0.015
dorsal ventral pattern formation GO:0009953 133 0.015
regulation of intracellular protein transport GO:0033157 46 0.015
regulation of chromatin organization GO:1902275 32 0.015
regulation of alternative mrna splicing via spliceosome GO:0000381 60 0.015
cell aging GO:0007569 2 0.015
protein k48 linked ubiquitination GO:0070936 3 0.015
rho protein signal transduction GO:0007266 14 0.015
pattern recognition receptor signaling pathway GO:0002221 2 0.015
modification dependent protein catabolic process GO:0019941 78 0.015
segmentation GO:0035282 207 0.015
regulation of proteolysis GO:0030162 87 0.015
kidney morphogenesis GO:0060993 3 0.015
salivary gland cell autophagic cell death GO:0035071 83 0.015
Fly
muscle cell development GO:0055001 50 0.015
immune system development GO:0002520 57 0.015
establishment of protein localization to organelle GO:0072594 62 0.015
regulation of antibacterial peptide biosynthetic process GO:0002808 22 0.015
apical constriction GO:0003383 18 0.015
Fly
epithelial cell migration GO:0010631 148 0.014
positive regulation of multi organism process GO:0043902 40 0.014
heart contraction GO:0060047 26 0.014
stress activated protein kinase signaling cascade GO:0031098 55 0.014
salivary gland development GO:0007431 162 0.014
Fly
stem cell development GO:0048864 79 0.014
positive regulation of calcium ion transport GO:0051928 4 0.014
positive regulation of immune system process GO:0002684 68 0.014
cation transmembrane transport GO:0098655 88 0.014
membrane fusion GO:0061025 42 0.014
pigment metabolic process GO:0042440 84 0.014
positive regulation of apoptotic process GO:0043065 47 0.014
Fly
lipid metabolic process GO:0006629 121 0.014
regulation of mrna processing GO:0050684 71 0.014
hemopoiesis GO:0030097 46 0.014
myotube differentiation GO:0014902 46 0.014
muscle tissue development GO:0060537 30 0.014
developmental growth GO:0048589 280 0.014
positive regulation of defense response to bacterium GO:1900426 23 0.014
cell junction assembly GO:0034329 42 0.014
positive regulation of cell motility GO:2000147 3 0.014
cell growth GO:0016049 108 0.013
calcium ion transport GO:0006816 24 0.013
male gamete generation GO:0048232 201 0.013
negative regulation of gene expression GO:0010629 387 0.013
heterocycle catabolic process GO:0046700 166 0.013
limb development GO:0060173 1 0.013
positive regulation of secretion by cell GO:1903532 20 0.013
regulation of cell morphogenesis GO:0022604 163 0.013
stem cell differentiation GO:0048863 117 0.013
mitotic cell cycle phase transition GO:0044772 138 0.013
myoblast fusion GO:0007520 43 0.013
circulatory system process GO:0003013 37 0.013
leg disc development GO:0035218 92 0.013
regulation of system process GO:0044057 36 0.013
regulation of rna splicing GO:0043484 69 0.013
enteroendocrine cell differentiation GO:0035883 1 0.013

Traf6 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.058
disease of cellular proliferation DOID:14566 0 0.022
cancer DOID:162 0 0.014
organ system cancer DOID:0050686 0 0.014
muscular disease DOID:0080000 0 0.013
musculoskeletal system disease DOID:17 0 0.013
muscle tissue disease DOID:66 0 0.013