Drosophila melanogaster

47 known processes

sphinx1 (Dmel_CG32383)

CG32383 gene product from transcript CG32383-RB

(Aliases: Dmel\CG32383,CG32383,SPH194,CG8555)

sphinx1 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
response to biotic stimulus GO:0009607 294 0.144
response to external biotic stimulus GO:0043207 293 0.140
response to other organism GO:0051707 293 0.137
defense response to other organism GO:0098542 225 0.133
immune system process GO:0002376 347 0.076
defense response GO:0006952 300 0.067
negative regulation of response to stimulus GO:0048585 258 0.057
negative regulation of signal transduction GO:0009968 206 0.050
defense response to gram negative bacterium GO:0050829 94 0.049
regulation of multi organism process GO:0043900 131 0.046
positive regulation of signal transduction GO:0009967 223 0.045
positive regulation of response to stimulus GO:0048584 323 0.045
response to bacterium GO:0009617 198 0.044
post embryonic appendage morphogenesis GO:0035120 385 0.042
immune response GO:0006955 246 0.041
defense response to bacterium GO:0042742 178 0.036
protein modification process GO:0036211 438 0.036
negative regulation of signaling GO:0023057 219 0.036
cellular protein modification process GO:0006464 438 0.035
positive regulation of signaling GO:0023056 243 0.035
vesicle mediated transport GO:0016192 381 0.034
gland morphogenesis GO:0022612 145 0.034
organonitrogen compound metabolic process GO:1901564 318 0.033
appendage development GO:0048736 401 0.033
intracellular signal transduction GO:0035556 300 0.033
appendage morphogenesis GO:0035107 397 0.032
regionalization GO:0003002 416 0.032
imaginal disc derived wing morphogenesis GO:0007476 337 0.032
imaginal disc derived appendage development GO:0048737 399 0.032
endocytosis GO:0006897 310 0.031
regulation of immune response GO:0050776 118 0.031
salivary gland development GO:0007431 162 0.031
regulation of multicellular organismal development GO:2000026 414 0.031
regulation of response to stress GO:0080134 200 0.030
wing disc morphogenesis GO:0007472 344 0.030
negative regulation of cell communication GO:0010648 223 0.030
negative regulation of cellular metabolic process GO:0031324 382 0.029
response to organic substance GO:0010033 284 0.029
positive regulation of cellular biosynthetic process GO:0031328 316 0.029
kidney development GO:0001822 3 0.029
regulation of defense response GO:0031347 102 0.028
regulation of immune system process GO:0002682 176 0.028
negative regulation of gene expression GO:0010629 387 0.028
antimicrobial humoral response GO:0019730 99 0.028
exocrine system development GO:0035272 162 0.028
imaginal disc derived appendage morphogenesis GO:0035114 395 0.028
innate immune response GO:0045087 144 0.027
columnar cuboidal epithelial cell differentiation GO:0002065 256 0.027
compound eye development GO:0048749 307 0.026
response to lipopolysaccharide GO:0032496 4 0.026
immune effector process GO:0002252 98 0.026
death GO:0016265 284 0.026
establishment of localization in cell GO:0051649 402 0.026
regulation of immune effector process GO:0002697 52 0.026
negative regulation of nitrogen compound metabolic process GO:0051172 265 0.025
phagocytosis GO:0006909 215 0.025
positive regulation of cell communication GO:0010647 250 0.025
positive regulation of nitrogen compound metabolic process GO:0051173 354 0.025
proteolysis GO:0006508 192 0.025
body morphogenesis GO:0010171 2 0.025
response to fungus GO:0009620 50 0.025
organic substance transport GO:0071702 257 0.025
defense response to fungus GO:0050832 48 0.025
respiratory system development GO:0060541 213 0.025
regulation of response to external stimulus GO:0032101 115 0.025
salivary gland morphogenesis GO:0007435 145 0.024
chaeta development GO:0022416 97 0.024
dna metabolic process GO:0006259 227 0.024
epithelial cell differentiation GO:0030855 322 0.024
lateral inhibition GO:0046331 206 0.024
epithelial cell development GO:0002064 274 0.024
small molecule metabolic process GO:0044281 305 0.023
activation of innate immune response GO:0002218 4 0.023
peptide metabolic process GO:0006518 80 0.023
protein hydroxylation GO:0018126 1 0.023
cell death GO:0008219 279 0.023
cell cell signaling involved in cell fate commitment GO:0045168 210 0.023
cholesterol homeostasis GO:0042632 3 0.023
immune response activating signal transduction GO:0002757 2 0.023
forebrain development GO:0030900 2 0.022
carboxylic acid metabolic process GO:0019752 92 0.022
response to abiotic stimulus GO:0009628 341 0.022
macromolecular complex assembly GO:0065003 256 0.022
programmed cell death GO:0012501 257 0.022
negative regulation of biosynthetic process GO:0009890 277 0.022
immune response regulating signaling pathway GO:0002764 2 0.022
cell motility GO:0048870 251 0.022
segmentation GO:0035282 207 0.022
defense response to gram positive bacterium GO:0050830 41 0.022
regulation of cell cycle GO:0051726 291 0.021
embryonic pattern specification GO:0009880 174 0.021
humoral immune response GO:0006959 117 0.021
columnar cuboidal epithelial cell development GO:0002066 249 0.021
lipopolysaccharide mediated signaling pathway GO:0031663 1 0.021
oxoacid metabolic process GO:0043436 103 0.021
organic acid metabolic process GO:0006082 103 0.021
eye development GO:0001654 323 0.021
homeostatic process GO:0042592 199 0.021
regulation of response to biotic stimulus GO:0002831 63 0.021
protein complex assembly GO:0006461 200 0.021
catabolic process GO:0009056 409 0.021
positive regulation of nucleobase containing compound metabolic process GO:0045935 332 0.021
regulation of intracellular signal transduction GO:1902531 236 0.021
single organism behavior GO:0044708 391 0.020
response to organophosphorus GO:0046683 2 0.020
innate immune response activating signal transduction GO:0002758 2 0.020
antimicrobial peptide production GO:0002775 46 0.020
protein complex biogenesis GO:0070271 201 0.020
regulation of protein metabolic process GO:0051246 256 0.020
gland development GO:0048732 191 0.020
anatomical structure homeostasis GO:0060249 97 0.020
nuclear division GO:0000280 332 0.020
amide biosynthetic process GO:0043604 42 0.020
cellular amide metabolic process GO:0043603 80 0.020
developmental growth GO:0048589 280 0.020
protein localization GO:0008104 284 0.019
positive regulation of rna biosynthetic process GO:1902680 266 0.019
organelle fission GO:0048285 340 0.019
telencephalon development GO:0021537 2 0.019
cellular response to dna damage stimulus GO:0006974 223 0.019
production of molecular mediator of immune response GO:0002440 46 0.019
regulation of cellular component biogenesis GO:0044087 201 0.019
camera type eye development GO:0043010 4 0.019
response to oxygen containing compound GO:1901700 200 0.019
regulation of cell differentiation GO:0045595 302 0.019
pattern recognition receptor signaling pathway GO:0002221 2 0.019
transcription from rna polymerase ii promoter GO:0006366 368 0.019
regulation of antimicrobial humoral response GO:0002759 50 0.019
spermatogenesis GO:0007283 200 0.019
positive regulation of biosynthetic process GO:0009891 316 0.018
carbohydrate derivative metabolic process GO:1901135 217 0.018
cell division GO:0051301 248 0.018
ovarian follicle cell development GO:0030707 248 0.018
regulation of antimicrobial peptide production GO:0002784 44 0.018
positive regulation of macromolecule biosynthetic process GO:0010557 283 0.018
negative regulation of macromolecule biosynthetic process GO:0010558 270 0.018
eye morphogenesis GO:0048592 260 0.018
central nervous system development GO:0007417 201 0.018
negative regulation of cellular macromolecule biosynthetic process GO:2000113 267 0.018
male gamete generation GO:0048232 201 0.018
negative regulation of rna metabolic process GO:0051253 251 0.018
single organism intracellular transport GO:1902582 207 0.018
organic substance catabolic process GO:1901575 308 0.018
sensory organ morphogenesis GO:0090596 260 0.018
wnt signaling pathway GO:0016055 98 0.018
detection of stimulus involved in sensory perception GO:0050906 92 0.018
single organism biosynthetic process GO:0044711 206 0.018
negative regulation of developmental process GO:0051093 201 0.017
regulation of innate immune response GO:0045088 71 0.017
connective tissue development GO:0061448 3 0.017
secondary metabolic process GO:0019748 75 0.017
regulation of humoral immune response GO:0002920 51 0.017
positive regulation of gene expression GO:0010628 290 0.017
peptidyl proline hydroxylation GO:0019511 1 0.017
cellular catabolic process GO:0044248 372 0.017
compound eye morphogenesis GO:0001745 249 0.017
tissue morphogenesis GO:0048729 297 0.017
negative regulation of nucleic acid templated transcription GO:1903507 240 0.016
cellular response to molecule of bacterial origin GO:0071219 3 0.016
antimicrobial peptide biosynthetic process GO:0002777 38 0.016
negative regulation of nucleobase containing compound metabolic process GO:0045934 261 0.016
cell proliferation GO:0008283 299 0.016
regulation of defense response to bacterium GO:1900424 30 0.016
cellular macromolecule localization GO:0070727 220 0.016
developmental programmed cell death GO:0010623 138 0.016
positive regulation of nucleic acid templated transcription GO:1903508 266 0.016
single organism catabolic process GO:0044712 228 0.016
regulation of i kappab kinase nf kappab signaling GO:0043122 2 0.016
single organism cellular localization GO:1902580 180 0.016
regulation of biosynthetic process of antibacterial peptides active against gram positive bacteria GO:0002816 3 0.016
negative regulation of rna biosynthetic process GO:1902679 240 0.016
negative regulation of cellular biosynthetic process GO:0031327 277 0.016
protein processing GO:0016485 68 0.016
regulation of catalytic activity GO:0050790 185 0.016
regulation of mitotic cell cycle GO:0007346 190 0.016
intracellular transport GO:0046907 228 0.016
positive regulation of macromolecule metabolic process GO:0010604 405 0.015
positive regulation of transcription dna templated GO:0045893 266 0.015
regulation of molecular function GO:0065009 217 0.015
organonitrogen compound biosynthetic process GO:1901566 117 0.015
growth GO:0040007 359 0.015
biological adhesion GO:0022610 138 0.015
ras protein signal transduction GO:0007265 88 0.015
rna processing GO:0006396 147 0.015
neurological system process GO:0050877 358 0.015
eye photoreceptor cell differentiation GO:0001754 145 0.015
positive regulation of rna metabolic process GO:0051254 271 0.015
regulation of cellular amide metabolic process GO:0034248 39 0.015
dna conformation change GO:0071103 105 0.015
muscle structure development GO:0061061 224 0.015
macromolecule catabolic process GO:0009057 161 0.015
organic hydroxy compound metabolic process GO:1901615 83 0.015
regulation of cell cycle process GO:0010564 181 0.015
sterol homeostasis GO:0055092 4 0.015
negative regulation of defense response GO:0031348 35 0.015
regulation of cellular amine metabolic process GO:0033238 3 0.015
blastoderm segmentation GO:0007350 159 0.015
cellular macromolecular complex assembly GO:0034622 153 0.015
regulation of mitotic cell cycle phase transition GO:1901990 130 0.015
detection of stimulus GO:0051606 156 0.015
photoreceptor cell differentiation GO:0046530 170 0.015
regulation of cellular protein metabolic process GO:0032268 243 0.015
regulation of cell death GO:0010941 173 0.015
regulation of mapk cascade GO:0043408 92 0.015
anterior posterior pattern specification GO:0009952 136 0.015
detection of chemical stimulus involved in sensory perception GO:0050907 75 0.014
peptidyl proline modification GO:0018208 3 0.014
response to nutrient levels GO:0031667 114 0.014
cellular amino acid metabolic process GO:0006520 61 0.014
localization of cell GO:0051674 257 0.014
chromosome organization GO:0051276 360 0.014
tube morphogenesis GO:0035239 191 0.014
morphogenesis of an epithelium GO:0002009 276 0.014
regulation of programmed cell death GO:0043067 152 0.014
positive regulation of transcription from rna polymerase ii promoter GO:0045944 204 0.014
chromosome segregation GO:0007059 157 0.014
mapk cascade GO:0000165 107 0.014
cellular component assembly involved in morphogenesis GO:0010927 151 0.014
protein heterooligomerization GO:0051291 4 0.014
retina development in camera type eye GO:0060041 4 0.014
regulation of cellular ketone metabolic process GO:0010565 3 0.014
monocarboxylic acid transport GO:0015718 3 0.014
protein transport GO:0015031 155 0.014
photoreceptor cell development GO:0042461 96 0.014
regulation of production of molecular mediator of immune response GO:0002700 44 0.013
intracellular protein transport GO:0006886 104 0.013
protein maturation GO:0051604 71 0.013
response to wounding GO:0009611 94 0.013
amine metabolic process GO:0009308 12 0.013
actin filament based process GO:0030029 220 0.013
cellular amine metabolic process GO:0044106 12 0.013
response to copper ion GO:0046688 4 0.013
signal transduction by phosphorylation GO:0023014 107 0.013
chemotaxis GO:0006935 249 0.013
tube development GO:0035295 244 0.013
cytoplasmic transport GO:0016482 130 0.013
taxis GO:0042330 304 0.013
phosphorylation GO:0016310 294 0.013
negative regulation of multicellular organismal process GO:0051241 142 0.013
regulation of wnt signaling pathway GO:0030111 68 0.013
positive regulation of multi organism process GO:0043902 40 0.013
endomembrane system organization GO:0010256 119 0.013
cell migration GO:0016477 238 0.013
compound eye photoreceptor cell differentiation GO:0001751 140 0.013
negative regulation of response to external stimulus GO:0032102 22 0.013
cellular protein localization GO:0034613 160 0.013
positive regulation of response to biotic stimulus GO:0002833 31 0.013
mitotic nuclear division GO:0007067 213 0.013
ethanolamine containing compound metabolic process GO:0042439 4 0.013
positive regulation of cell migration GO:0030335 2 0.013
regulation of localization GO:0032879 275 0.013
regulation of cell development GO:0060284 215 0.013
apoptotic process GO:0006915 159 0.013
response to radiation GO:0009314 155 0.013
cellular response to lipopolysaccharide GO:0071222 3 0.013
muscle organ development GO:0007517 127 0.013
regulation of transcription from rna polymerase ii promoter GO:0006357 378 0.013
negative regulation of transcription dna templated GO:0045892 237 0.013
establishment of protein localization GO:0045184 163 0.013
positive regulation of cell motility GO:2000147 3 0.012
regulation of organelle organization GO:0033043 196 0.012
cellular response to chemical stimulus GO:0070887 199 0.012
rhythmic process GO:0048511 106 0.012
positive regulation of response to external stimulus GO:0032103 44 0.012
regulation of transport GO:0051049 181 0.012
notch signaling pathway GO:0007219 120 0.012
regulation of apoptotic process GO:0042981 130 0.012
carbohydrate derivative biosynthetic process GO:1901137 85 0.012
negative regulation of cellular protein metabolic process GO:0032269 85 0.012
peptidyl amino acid modification GO:0018193 105 0.012
imaginal disc pattern formation GO:0007447 91 0.012
cell cycle phase transition GO:0044770 140 0.012
chromatin modification GO:0016568 147 0.012
nucleobase containing small molecule metabolic process GO:0055086 174 0.012
stress activated mapk cascade GO:0051403 52 0.012
organophosphate metabolic process GO:0019637 195 0.012
regulation of phosphorus metabolic process GO:0051174 210 0.012
positive regulation of intracellular signal transduction GO:1902533 116 0.012
positive regulation of defense response GO:0031349 59 0.012
nephron epithelium development GO:0072009 3 0.012
small gtpase mediated signal transduction GO:0007264 88 0.012
neuron projection guidance GO:0097485 241 0.012
spindle organization GO:0007051 253 0.012
axis specification GO:0009798 167 0.012
regulation of notch signaling pathway GO:0008593 100 0.012
neutral lipid biosynthetic process GO:0046460 2 0.012
organelle assembly GO:0070925 198 0.012
regulation of epithelial cell differentiation GO:0030856 4 0.012
cellular response to biotic stimulus GO:0071216 4 0.012
tissue death GO:0016271 102 0.012
compound eye photoreceptor development GO:0042051 78 0.012
gene silencing GO:0016458 138 0.012
meiotic cell cycle process GO:1903046 132 0.012
regulation of proteolysis GO:0030162 87 0.012
cellular response to organic substance GO:0071310 132 0.012
anion homeostasis GO:0055081 3 0.012
peptide biosynthetic process GO:0043043 42 0.012
regulation of antimicrobial peptide biosynthetic process GO:0002805 38 0.012
neuron recognition GO:0008038 101 0.012
embryonic development via the syncytial blastoderm GO:0001700 148 0.012
dorsal ventral pattern formation GO:0009953 133 0.012
biosynthetic process of antibacterial peptides active against gram positive bacteria GO:0002815 3 0.012
rna localization GO:0006403 115 0.012
mesenchymal cell development GO:0014031 1 0.012
cell adhesion GO:0007155 136 0.012
multi organism behavior GO:0051705 175 0.012
chromatin organization GO:0006325 207 0.012
negative regulation of cell differentiation GO:0045596 143 0.012
chromatin assembly or disassembly GO:0006333 52 0.011
developmental maturation GO:0021700 172 0.011
cell recognition GO:0008037 102 0.011
ribose phosphate metabolic process GO:0019693 145 0.011
hindbrain development GO:0030902 2 0.011
negative regulation of growth GO:0045926 84 0.011
digestive tract development GO:0048565 149 0.011
hematopoietic progenitor cell differentiation GO:0002244 1 0.011
carbohydrate metabolic process GO:0005975 82 0.011
eggshell formation GO:0030703 105 0.011
antibacterial humoral response GO:0019731 44 0.011
multicellular organismal aging GO:0010259 140 0.011
response to extracellular stimulus GO:0009991 116 0.011
regulation of cell cycle phase transition GO:1901987 130 0.011
detection of chemical stimulus GO:0009593 93 0.011
wound healing GO:0042060 75 0.011
regulation of catabolic process GO:0009894 170 0.011
regulation of anatomical structure size GO:0090066 163 0.011
negative regulation of protein metabolic process GO:0051248 85 0.011
protein phosphorylation GO:0006468 169 0.011
eye photoreceptor cell development GO:0042462 81 0.011
regulation of embryonic development GO:0045995 68 0.011
nucleoside phosphate metabolic process GO:0006753 162 0.011
mesenchymal cell differentiation GO:0048762 1 0.011
mitotic cell cycle phase transition GO:0044772 138 0.011
purine ribonucleotide metabolic process GO:0009150 145 0.011
sensory perception of chemical stimulus GO:0007606 116 0.011
autophagic cell death GO:0048102 83 0.011
chemical homeostasis GO:0048878 92 0.011
regulation of antibacterial peptide production GO:0002786 22 0.011
positive regulation of biosynthetic process of antibacterial peptides active against gram positive bacteria GO:0006965 3 0.011
cellular ketone metabolic process GO:0042180 24 0.011
positive regulation of defense response to bacterium GO:1900426 23 0.011
organic cyclic compound catabolic process GO:1901361 168 0.011
mitotic spindle organization GO:0007052 220 0.011
kidney morphogenesis GO:0060993 3 0.011
triglyceride biosynthetic process GO:0019432 2 0.011
histolysis GO:0007559 102 0.011
positive regulation of immune response GO:0050778 63 0.011
response to monosaccharide GO:0034284 4 0.011
brain development GO:0007420 120 0.011
adult behavior GO:0030534 137 0.011
stem cell proliferation GO:0072089 88 0.011
negative regulation of peptidoglycan recognition protein signaling pathway GO:0061060 3 0.010
nephron tubule development GO:0072080 3 0.010
melanization defense response GO:0035006 45 0.010
regulation of cellular amino acid metabolic process GO:0006521 0 0.010
nucleotide metabolic process GO:0009117 161 0.010
protein targeting GO:0006605 64 0.010
embryo development ending in birth or egg hatching GO:0009792 152 0.010
developmental pigmentation GO:0048066 68 0.010
spermatid differentiation GO:0048515 114 0.010
organonitrogen compound catabolic process GO:1901565 128 0.010
nephron epithelium morphogenesis GO:0072088 3 0.010
negative regulation of immune response GO:0050777 39 0.010
non sensory hair organization GO:0035316 47 0.010
heterocycle catabolic process GO:0046700 166 0.010
sperm competition GO:0046692 21 0.010
negative regulation of nervous system development GO:0051961 92 0.010
somatic muscle development GO:0007525 66 0.010
nephron development GO:0072006 3 0.010
autophagy GO:0006914 108 0.010
regulation of growth GO:0040008 233 0.010
eggshell chorion assembly GO:0007306 66 0.010
negative regulation of cellular component organization GO:0051129 108 0.010
salivary gland histolysis GO:0035070 88 0.010
dendrite morphogenesis GO:0048813 199 0.010
establishment of tissue polarity GO:0007164 87 0.010
stem cell division GO:0017145 69 0.010
actin cytoskeleton organization GO:0030036 206 0.010
positive regulation of cellular amino acid metabolic process GO:0045764 0 0.010

sphinx1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.033
disease of metabolism DOID:0014667 0 0.015
nervous system disease DOID:863 0 0.014
acquired metabolic disease DOID:0060158 0 0.011
inherited metabolic disorder DOID:655 0 0.011