Drosophila melanogaster

42 known processes

sds22 (Dmel_CG5851)

CG5851 gene product from transcript CG5851-RA

(Aliases: CG5851,CT18355,Dmel\CG5851)

sds22 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
negative regulation of cellular metabolic process GO:0031324 382 0.703
cullin deneddylation GO:0010388 3 0.419
intracellular signal transduction GO:0035556 300 0.398
establishment of localization in cell GO:0051649 402 0.325
protein modification process GO:0036211 438 0.314
Human
endosomal vesicle fusion GO:0034058 4 0.299
endocytosis GO:0006897 310 0.258
Worm
regulation of intracellular signal transduction GO:1902531 236 0.251
eye development GO:0001654 323 0.241
dna integrity checkpoint GO:0031570 81 0.238
response to abiotic stimulus GO:0009628 341 0.225
cellular protein modification process GO:0006464 438 0.220
Human
regulation of cell death GO:0010941 173 0.213
regulation of cell cycle GO:0051726 291 0.203
single organism behavior GO:0044708 391 0.195
dna damage checkpoint GO:0000077 78 0.176
regulation of mitotic cell cycle GO:0007346 190 0.160
germ line cyst formation GO:0048134 44 0.155
vesicle mediated transport GO:0016192 381 0.153
Worm
regulation of cell cycle process GO:0010564 181 0.147
oocyte microtubule cytoskeleton polarization GO:0008103 22 0.146
organic substance transport GO:0071702 257 0.144
larval development GO:0002164 104 0.142
regulation of cellular protein metabolic process GO:0032268 243 0.140
Human
regulation of transport GO:0051049 181 0.134
apoptotic process GO:0006915 159 0.132
regulation of apoptotic process GO:0042981 130 0.127
negative regulation of cell cycle GO:0045786 116 0.122
protein localization GO:0008104 284 0.118
mitotic dna damage checkpoint GO:0044773 74 0.117
protein deneddylation GO:0000338 8 0.112
cell cycle checkpoint GO:0000075 95 0.110
negative regulation of signaling GO:0023057 219 0.108
negative regulation of gene expression GO:0010629 387 0.104
regulation of developmental growth GO:0048638 174 0.104
positive regulation of cell communication GO:0010647 250 0.103
positive regulation of signaling GO:0023056 243 0.100
phosphorylation GO:0016310 294 0.096
negative regulation of response to stimulus GO:0048585 258 0.096
cell proliferation GO:0008283 299 0.096
germarium derived female germ line cyst formation GO:0030727 42 0.093
negative regulation of cellular macromolecule biosynthetic process GO:2000113 267 0.093
regulation of cellular localization GO:0060341 136 0.087
negative regulation of signal transduction GO:0009968 206 0.087
g2 dna damage checkpoint GO:0031572 69 0.083
response to organic substance GO:0010033 284 0.082
dephosphorylation GO:0016311 51 0.080
Human
negative regulation of mitotic cell cycle GO:0045930 109 0.080
establishment or maintenance of cytoskeleton polarity GO:0030952 44 0.080
single organism membrane organization GO:0044802 93 0.079
negative regulation of macromolecule biosynthetic process GO:0010558 270 0.079
modification dependent macromolecule catabolic process GO:0043632 79 0.077
compound eye development GO:0048749 307 0.076
oocyte development GO:0048599 124 0.074
negative regulation of cellular biosynthetic process GO:0031327 277 0.073
compound eye morphogenesis GO:0001745 249 0.070
positive regulation of transcription dna templated GO:0045893 266 0.069
positive regulation of response to stimulus GO:0048584 323 0.069
mitotic cell cycle phase transition GO:0044772 138 0.068
cytoskeleton dependent cytokinesis GO:0061640 81 0.068
eye morphogenesis GO:0048592 260 0.068
oocyte axis specification GO:0007309 108 0.068
negative regulation of biosynthetic process GO:0009890 277 0.066
regulation of phosphate metabolic process GO:0019220 210 0.066
Human
sex differentiation GO:0007548 81 0.065
Worm
regulation of localization GO:0032879 275 0.065
female germ line cyst formation GO:0048135 42 0.063
regulation of catalytic activity GO:0050790 185 0.063
negative regulation of cellular protein metabolic process GO:0032269 85 0.063
regulation of lamellipodium assembly GO:0010591 15 0.063
oocyte construction GO:0007308 112 0.062
regulation of neuron projection development GO:0010975 69 0.061
positive regulation of signal transduction GO:0009967 223 0.060
establishment or maintenance of bipolar cell polarity GO:0061245 34 0.059
establishment or maintenance of cell polarity GO:0007163 167 0.059
modification dependent protein catabolic process GO:0019941 78 0.058
regulation of lamellipodium organization GO:1902743 15 0.058
response to oxygen containing compound GO:1901700 200 0.058
cell cycle phase transition GO:0044770 140 0.058
regulation of vesicle mediated transport GO:0060627 59 0.057
actin filament capping GO:0051693 2 0.057
cellular protein localization GO:0034613 160 0.057
negative regulation of transcription dna templated GO:0045892 237 0.056
regulation of cell cycle phase transition GO:1901987 130 0.054
regulation of protein stability GO:0031647 43 0.054
morphogenesis of an epithelium GO:0002009 276 0.054
establishment of protein localization GO:0045184 163 0.053
regulation of growth GO:0040008 233 0.052
negative regulation of protein metabolic process GO:0051248 85 0.051
learning or memory GO:0007611 141 0.050
positive regulation of nucleic acid templated transcription GO:1903508 266 0.049
mitotic cell cycle checkpoint GO:0007093 88 0.049
intracellular transport GO:0046907 228 0.048
negative regulation of phosphorus metabolic process GO:0010563 45 0.048
mitotic nuclear division GO:0007067 213 0.048
organelle fission GO:0048285 340 0.047
endomembrane system organization GO:0010256 119 0.047
regulation of molecular function GO:0065009 217 0.046
proteolysis GO:0006508 192 0.046
negative regulation of cell cycle process GO:0010948 109 0.046
death GO:0016265 284 0.045
regulation of multi organism process GO:0043900 131 0.045
regulation of protein metabolic process GO:0051246 256 0.045
Human
negative regulation of mitotic cell cycle phase transition GO:1901991 103 0.045
axon development GO:0061564 297 0.045
membrane organization GO:0061024 112 0.045
regulation of proteolysis involved in cellular protein catabolic process GO:1903050 44 0.045
negative regulation of phosphate metabolic process GO:0045936 45 0.045
regulation of mitotic cell cycle phase transition GO:1901990 130 0.045
cellular protein catabolic process GO:0044257 83 0.045
negative regulation of cellular component organization GO:0051129 108 0.044
negative regulation of cell cycle phase transition GO:1901988 103 0.044
regulation of organelle organization GO:0033043 196 0.043
arp2 3 complex mediated actin nucleation GO:0034314 3 0.043
sensory organ morphogenesis GO:0090596 260 0.043
negative regulation of catalytic activity GO:0043086 42 0.043
cytoplasmic transport GO:0016482 130 0.042
mitotic dna integrity checkpoint GO:0044774 75 0.042
multi multicellular organism process GO:0044706 123 0.041
cell maturation GO:0048469 144 0.040
regulation of proteasomal ubiquitin dependent protein catabolic process GO:0032434 37 0.040
regulation of programmed cell death GO:0043067 152 0.040
positive regulation of intracellular signal transduction GO:1902533 116 0.039
membrane budding GO:0006900 4 0.039
regulation of protein polymerization GO:0032271 28 0.038
negative regulation of cell communication GO:0010648 223 0.037
lateral inhibition GO:0046331 206 0.036
protein modification by small protein conjugation or removal GO:0070647 106 0.036
negative regulation of cell proliferation GO:0008285 69 0.036
single organism cellular localization GO:1902580 180 0.036
notch signaling pathway GO:0007219 120 0.035
homeostatic process GO:0042592 199 0.034
regulation of mapk cascade GO:0043408 92 0.034
epithelial cell differentiation GO:0030855 322 0.034
positive regulation of macromolecule biosynthetic process GO:0010557 283 0.034
signal transduction by phosphorylation GO:0023014 107 0.033
chemotaxis GO:0006935 249 0.033
cellularization GO:0007349 90 0.033
negative regulation of organelle organization GO:0010639 56 0.033
phagocytosis GO:0006909 215 0.033
chromosome organization GO:0051276 360 0.032
negative regulation of protein depolymerization GO:1901880 23 0.032
body morphogenesis GO:0010171 2 0.032
response to temperature stimulus GO:0009266 106 0.031
response to nitrogen compound GO:1901698 90 0.031
gonad development GO:0008406 50 0.031
Worm
mitotic g2 dna damage checkpoint GO:0007095 69 0.031
autophagic vacuole fusion GO:0000046 15 0.031
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 116 0.030
positive regulation of cell death GO:0010942 69 0.030
single organism membrane budding GO:1902591 2 0.029
nuclear division GO:0000280 332 0.029
single organism intracellular transport GO:1902582 207 0.029
early endosome to late endosome transport GO:0045022 3 0.029
development of primary sexual characteristics GO:0045137 50 0.029
Worm
regulation of cellular amino acid metabolic process GO:0006521 0 0.028
positive regulation of multi organism process GO:0043902 40 0.028
jak stat cascade GO:0007259 49 0.028
regulation of cell projection organization GO:0031344 92 0.028
regulation of actin filament length GO:0030832 27 0.028
proteolysis involved in cellular protein catabolic process GO:0051603 83 0.028
organic substance catabolic process GO:1901575 308 0.027
cell death GO:0008219 279 0.027
protein transport GO:0015031 155 0.027
negative regulation of developmental process GO:0051093 201 0.026
photoreceptor cell differentiation GO:0046530 170 0.026
regulation of small gtpase mediated signal transduction GO:0051056 93 0.026
mapk cascade GO:0000165 107 0.025
regulation of cytoskeleton organization GO:0051493 89 0.025
chromosome segregation GO:0007059 157 0.025
Mouse
regulation of cytoplasmic transport GO:1903649 47 0.025
developmental growth GO:0048589 280 0.025
regulation of catabolic process GO:0009894 170 0.025
neuron remodeling GO:0016322 29 0.024
proteasomal protein catabolic process GO:0010498 59 0.024
response to heat GO:0009408 63 0.024
regulation of protein modification process GO:0031399 112 0.024
Human
regulation of transcription from rna polymerase ii promoter GO:0006357 378 0.024
regulation of notch signaling pathway GO:0008593 100 0.024
negative regulation of nucleobase containing compound metabolic process GO:0045934 261 0.024
regulation of phosphorus metabolic process GO:0051174 210 0.024
Human
defense response to gram negative bacterium GO:0050829 94 0.024
mitotic g2 m transition checkpoint GO:0044818 70 0.023
negative regulation of cell death GO:0060548 81 0.023
cell division GO:0051301 248 0.023
regulation of cell development GO:0060284 215 0.022
cognition GO:0050890 141 0.022
regulation of ras protein signal transduction GO:0046578 93 0.022
adult behavior GO:0030534 137 0.022
single organism nuclear import GO:1902593 51 0.022
positive regulation of phosphorus metabolic process GO:0010562 139 0.022
Human
protein catabolic process GO:0030163 101 0.022
chemosensory behavior GO:0007635 106 0.022
ubiquitin dependent protein catabolic process GO:0006511 78 0.022
anatomical structure homeostasis GO:0060249 97 0.022
embryo development ending in birth or egg hatching GO:0009792 152 0.021
Worm
small gtpase mediated signal transduction GO:0007264 88 0.021
ubiquitin dependent protein catabolic process via the multivesicular body sorting pathway GO:0043162 8 0.021
catabolic process GO:0009056 409 0.021
negative regulation of nucleic acid templated transcription GO:1903507 240 0.021
negative regulation of protein modification process GO:0031400 29 0.021
protein dephosphorylation GO:0006470 27 0.021
Human
response to endogenous stimulus GO:0009719 119 0.020
protein deubiquitination GO:0016579 17 0.020
negative regulation of intracellular signal transduction GO:1902532 57 0.020
response to organonitrogen compound GO:0010243 75 0.020
regulation of cellular protein catabolic process GO:1903362 44 0.020
ras protein signal transduction GO:0007265 88 0.020
regulation of cell differentiation GO:0045595 302 0.020
carbohydrate derivative metabolic process GO:1901135 217 0.019
leg disc morphogenesis GO:0007478 80 0.019
positive regulation of nucleobase containing compound metabolic process GO:0045935 332 0.019
columnar cuboidal epithelial cell development GO:0002066 249 0.019
developmental maturation GO:0021700 172 0.018
pigment metabolic process GO:0042440 84 0.018
positive regulation of developmental process GO:0051094 143 0.018
cytokinesis GO:0000910 90 0.018
establishment of protein localization to organelle GO:0072594 62 0.018
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 54 0.018
cellular macromolecule localization GO:0070727 220 0.018
wnt signaling pathway GO:0016055 98 0.018
epidermal cell differentiation GO:0009913 51 0.018
cellular response to chemical stimulus GO:0070887 199 0.017
positive regulation of proteasomal protein catabolic process GO:1901800 20 0.017
regulation of cellular response to stress GO:0080135 89 0.017
reproductive structure development GO:0048608 74 0.017
Worm
synaptic transmission GO:0007268 288 0.017
regulation of actin filament polymerization GO:0030833 25 0.017
neurological system process GO:0050877 358 0.017
growth GO:0040007 359 0.017
cell cell signaling involved in cell fate commitment GO:0045168 210 0.016
regulation of proteasomal protein catabolic process GO:0061136 39 0.016
eye photoreceptor cell differentiation GO:0001754 145 0.016
protein import into nucleus GO:0006606 51 0.016
enzyme linked receptor protein signaling pathway GO:0007167 179 0.016
protein localization to organelle GO:0033365 82 0.016
establishment of organelle localization GO:0051656 122 0.016
response to radiation GO:0009314 155 0.016
oocyte differentiation GO:0009994 145 0.016
regulation of protein catabolic process GO:0042176 55 0.016
protein maturation GO:0051604 71 0.015
positive regulation of nitrogen compound metabolic process GO:0051173 354 0.015
response to virus GO:0009615 28 0.015
positive regulation of defense response GO:0031349 59 0.015
establishment of nucleus localization GO:0040023 26 0.015
protein modification by small protein conjugation GO:0032446 79 0.015
response to other organism GO:0051707 293 0.015
negative regulation of molecular function GO:0044092 51 0.014
germarium derived egg chamber formation GO:0007293 101 0.014
localization of cell GO:0051674 257 0.014
regulation of response to stress GO:0080134 200 0.014
dorsal ventral pattern formation GO:0009953 133 0.014
response to ionizing radiation GO:0010212 32 0.014
positive regulation of apoptotic process GO:0043065 47 0.014
axonogenesis GO:0007409 290 0.014
defense response to other organism GO:0098542 225 0.014
regulation of cell proliferation GO:0042127 163 0.014
regulation of actin filament depolymerization GO:0030834 3 0.014
nitrogen compound transport GO:0071705 85 0.014
regulation of multicellular organismal development GO:2000026 414 0.013
neuron projection guidance GO:0097485 241 0.013
defense response to bacterium GO:0042742 178 0.013
cell migration GO:0016477 238 0.013
vesicle organization GO:0016050 44 0.013
intracellular protein transport GO:0006886 104 0.013
organonitrogen compound metabolic process GO:1901564 318 0.013
nuclear migration GO:0007097 20 0.013
negative regulation of programmed cell death GO:0043069 72 0.013
retina development in camera type eye GO:0060041 4 0.013
negative regulation of actin filament depolymerization GO:0030835 2 0.013
transcription from rna polymerase ii promoter GO:0006366 368 0.012
membrane biogenesis GO:0044091 8 0.012
regulation of locomotion GO:0040012 42 0.012
oocyte microtubule cytoskeleton organization GO:0016325 35 0.012
rrna processing GO:0006364 3 0.012
regulation of protein phosphorylation GO:0001932 64 0.012
camera type eye development GO:0043010 4 0.012
appendage segmentation GO:0035285 26 0.012
negative regulation of nitrogen compound metabolic process GO:0051172 265 0.012
programmed cell death GO:0012501 257 0.012
actin polymerization or depolymerization GO:0008154 31 0.012
regulation of establishment of protein localization GO:0070201 61 0.012
regulation of cell projection assembly GO:0060491 30 0.012
nucleotide metabolic process GO:0009117 161 0.012
regulation of protein localization GO:0032880 76 0.012
central nervous system development GO:0007417 201 0.012
negative regulation of multicellular organismal process GO:0051241 142 0.012
positive regulation of multicellular organismal process GO:0051240 143 0.011
protein ubiquitination GO:0016567 70 0.011
axis specification GO:0009798 167 0.011
negative regulation of apoptotic process GO:0043066 63 0.011
regulation of nervous system development GO:0051960 248 0.011
cell motility GO:0048870 251 0.011
cell cycle arrest GO:0007050 4 0.011
positive regulation of rna biosynthetic process GO:1902680 266 0.011
reproductive system development GO:0061458 74 0.011
Worm
establishment of imaginal disc derived wing hair orientation GO:0001737 24 0.011
cell growth GO:0016049 108 0.011
regulation of mitosis GO:0007088 56 0.011
positive regulation of molecular function GO:0044093 136 0.011
genitalia development GO:0048806 26 0.011
Worm
reproductive behavior GO:0019098 122 0.011
positive regulation of cellular component biogenesis GO:0044089 80 0.011
regulation of system process GO:0044057 36 0.010
synaptic vesicle localization GO:0097479 53 0.010
negative regulation of epithelial cell proliferation GO:0050680 4 0.010
protein modification by small protein removal GO:0070646 28 0.010
actin filament depolymerization GO:0030042 5 0.010
regulation of secretion by cell GO:1903530 39 0.010
response to external biotic stimulus GO:0043207 293 0.010
protein phosphorylation GO:0006468 169 0.010
rhythmic process GO:0048511 106 0.010
organophosphate metabolic process GO:0019637 195 0.010
multicellular organismal reproductive behavior GO:0033057 110 0.010
positive regulation of gene expression GO:0010628 290 0.010
regulation of nucleotide metabolic process GO:0006140 62 0.010

sds22 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.042
cancer DOID:162 0 0.026
disease of cellular proliferation DOID:14566 0 0.026