Drosophila melanogaster

208 known processes

Rab5 (Dmel_CG3664)

Rab-protein 5

(Aliases: Dm Rab5,l(2)k08232,BAA88244,AAF51265,DRab5,Dmel\CG3664,rab5,DmRab5,dRab5,CG3664,Rab,RAB5a,Drab5,RAB5)

Rab5 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
germarium derived egg chamber formation GO:0007293 101 1.000
germ line cyst formation GO:0048134 44 0.999
female germ line cyst formation GO:0048135 42 0.998
ovarian follicle cell development GO:0030707 248 0.997
cell migration GO:0016477 238 0.997
epithelial cell migration GO:0010631 148 0.997
organelle localization GO:0051640 148 0.996
regulation of vesicle mediated transport GO:0060627 59 0.996
ameboidal type cell migration GO:0001667 151 0.995
cell division GO:0051301 248 0.994
Worm
cell motility GO:0048870 251 0.991
columnar cuboidal epithelial cell differentiation GO:0002065 256 0.987
exocytosis GO:0006887 28 0.986
Human
asymmetric neuroblast division GO:0055059 33 0.984
single organism membrane fusion GO:0044801 42 0.982
axonogenesis GO:0007409 290 0.980
columnar cuboidal epithelial cell development GO:0002066 249 0.979
localization of cell GO:0051674 257 0.976
epithelium migration GO:0090132 148 0.975
oocyte microtubule cytoskeleton organization GO:0016325 35 0.975
synaptic transmission GO:0007268 288 0.972
cellular macromolecule localization GO:0070727 220 0.967
Yeast
oocyte development GO:0048599 124 0.966
membrane fusion GO:0061025 42 0.965
organelle fusion GO:0048284 46 0.959
phosphorylation GO:0016310 294 0.949
germarium derived female germ line cyst formation GO:0030727 42 0.948
epithelial cell development GO:0002064 274 0.944
synapse assembly GO:0007416 143 0.943
regulation of cell morphogenesis GO:0022604 163 0.943
oocyte differentiation GO:0009994 145 0.938
tissue migration GO:0090130 155 0.933
single organism membrane organization GO:0044802 93 0.917
single organism intracellular transport GO:1902582 207 0.914
neuron projection extension GO:1990138 32 0.913
neuromuscular synaptic transmission GO:0007274 67 0.910
synapse organization GO:0050808 196 0.907
single organism cellular localization GO:1902580 180 0.895
Yeast
synaptic growth at neuromuscular junction GO:0051124 119 0.880
homeostatic process GO:0042592 199 0.879
meiotic cell cycle GO:0051321 171 0.877
establishment of cell polarity GO:0030010 40 0.874
oocyte axis specification GO:0007309 108 0.869
ovarian follicle cell migration GO:0007297 121 0.860
oocyte construction GO:0007308 112 0.855
cellular protein localization GO:0034613 160 0.849
Yeast
endosome transport via multivesicular body sorting pathway GO:0032509 12 0.849
Yeast
regulation of cell proliferation GO:0042127 163 0.845
regulation of dendrite morphogenesis GO:0048814 28 0.835
vesicle mediated transport GO:0016192 381 0.835
response to extracellular stimulus GO:0009991 116 0.829
post embryonic appendage morphogenesis GO:0035120 385 0.828
axon development GO:0061564 297 0.799
dorsal closure amnioserosa morphology change GO:0046664 7 0.797
vesicle organization GO:0016050 44 0.791
regulation of localization GO:0032879 275 0.791
tube morphogenesis GO:0035239 191 0.783
Zebrafish
protein phosphorylation GO:0006468 169 0.774
regulation of intracellular signal transduction GO:1902531 236 0.761
tube development GO:0035295 244 0.756
Zebrafish
regulation of synaptic growth at neuromuscular junction GO:0008582 89 0.753
establishment or maintenance of cell polarity GO:0007163 167 0.750
regulation of synapse structure and activity GO:0050803 128 0.745
enzyme linked receptor protein signaling pathway GO:0007167 179 0.742
lipid metabolic process GO:0006629 121 0.735
Worm
regulation of protein modification process GO:0031399 112 0.734
regulation of synapse assembly GO:0051963 94 0.718
developmental maturation GO:0021700 172 0.718
neuromuscular junction development GO:0007528 149 0.712
initiation of dorsal closure GO:0007392 12 0.701
positive regulation of macromolecule metabolic process GO:0010604 405 0.701
establishment of organelle localization GO:0051656 122 0.700
glycosyl compound catabolic process GO:1901658 112 0.699
Human Yeast Mouse Worm
establishment or maintenance of cytoskeleton polarity GO:0030952 44 0.695
taxis GO:0042330 304 0.681
regulation of endocytosis GO:0030100 37 0.675
regulation of phosphorylation GO:0042325 147 0.670
protein modification process GO:0036211 438 0.659
regulation of cell shape GO:0008360 113 0.657
cellular response to extracellular stimulus GO:0031668 64 0.652
regulation of synaptic transmission GO:0050804 69 0.651
Human
regulation of protein metabolic process GO:0051246 256 0.646
tissue morphogenesis GO:0048729 297 0.646
positive regulation of signaling GO:0023056 243 0.643
membrane organization GO:0061024 112 0.639
cell proliferation GO:0008283 299 0.635
eye morphogenesis GO:0048592 260 0.633
synaptic vesicle transport GO:0048489 50 0.633
embryonic development via the syncytial blastoderm GO:0001700 148 0.630
cellular protein modification process GO:0006464 438 0.629
cytoplasmic transport nurse cell to oocyte GO:0007303 12 0.625
neuroblast proliferation GO:0007405 74 0.622
regulation of phosphate metabolic process GO:0019220 210 0.620
apoptotic cell clearance GO:0043277 14 0.618
Worm
regulation of axonogenesis GO:0050770 32 0.617
synaptic vesicle recycling GO:0036465 28 0.616
regulation of cellular component biogenesis GO:0044087 201 0.614
Human
cortical actin cytoskeleton organization GO:0030866 24 0.613
negative regulation of gene expression GO:0010629 387 0.607
negative regulation of response to stimulus GO:0048585 258 0.592
intracellular transport GO:0046907 228 0.589
axon guidance GO:0007411 233 0.586
neuroblast division GO:0055057 35 0.581
regulation of anatomical structure morphogenesis GO:0022603 242 0.575
establishment or maintenance of apical basal cell polarity GO:0035088 34 0.571
eye development GO:0001654 323 0.559
positive regulation of cellular component organization GO:0051130 156 0.551
negative regulation of signaling GO:0023057 219 0.546
skin development GO:0043588 65 0.545
regulation of cell cycle process GO:0010564 181 0.544
cellular response to nutrient levels GO:0031669 62 0.544
protein localization GO:0008104 284 0.538
Yeast Worm
cell maturation GO:0048469 144 0.529
establishment of synaptic vesicle localization GO:0097480 50 0.525
regulation of erbb signaling pathway GO:1901184 42 0.508
oocyte microtubule cytoskeleton polarization GO:0008103 22 0.495
epithelial cell differentiation GO:0030855 322 0.490
regulation of exocytosis GO:0017157 6 0.489
Human
axon extension GO:0048675 32 0.483
catabolic process GO:0009056 409 0.481
Human Yeast Mouse Worm
centrosome duplication GO:0051298 121 0.480
regulation of epidermal growth factor receptor signaling pathway GO:0042058 42 0.472
vesicle localization GO:0051648 55 0.470
cellular response to starvation GO:0009267 61 0.469
regulation of growth GO:0040008 233 0.467
inorganic cation transmembrane transport GO:0098662 61 0.465
protein complex biogenesis GO:0070271 201 0.465
endosomal transport GO:0016197 44 0.463
cellular lipid metabolic process GO:0044255 83 0.462
dna metabolic process GO:0006259 227 0.460
establishment of protein localization GO:0045184 163 0.454
Yeast Worm
oocyte anterior posterior axis specification GO:0007314 72 0.454
mitotic nuclear division GO:0007067 213 0.452
regulation of protein phosphorylation GO:0001932 64 0.447
protein transport GO:0015031 155 0.445
Yeast Worm
establishment of localization in cell GO:0051649 402 0.433
stem cell division GO:0017145 69 0.428
protein localization to organelle GO:0033365 82 0.424
Yeast
biological adhesion GO:0022610 138 0.421
Zebrafish
morphogenesis of a branching structure GO:0001763 45 0.411
response to abiotic stimulus GO:0009628 341 0.405
spindle organization GO:0007051 253 0.404
regulation of cell development GO:0060284 215 0.401
ion homeostasis GO:0050801 55 0.397
compound eye morphogenesis GO:0001745 249 0.394
regulation of organelle organization GO:0033043 196 0.389
epidermis development GO:0008544 65 0.388
microtubule organizing center organization GO:0031023 168 0.386
cytoplasm organization GO:0007028 64 0.385
Worm
mapk cascade GO:0000165 107 0.378
intracellular protein transport GO:0006886 104 0.372
Yeast
rna localization GO:0006403 115 0.371
actin cytoskeleton reorganization GO:0031532 22 0.371
regulation of protein kinase activity GO:0045859 51 0.371
adult locomotory behavior GO:0008344 76 0.369
nuclear migration GO:0007097 20 0.368
notch signaling pathway GO:0007219 120 0.364
negative regulation of nitrogen compound metabolic process GO:0051172 265 0.364
endocytosis GO:0006897 310 0.363
cognition GO:0050890 141 0.358
protein complex assembly GO:0006461 200 0.355
jnk cascade GO:0007254 50 0.355
response to radiation GO:0009314 155 0.350
regulation of cellular protein metabolic process GO:0032268 243 0.349
centrosome organization GO:0051297 163 0.349
macroautophagy GO:0016236 42 0.347
secretion GO:0046903 109 0.346
Human Worm
regulation of cytoskeleton organization GO:0051493 89 0.346
regulation of synapse organization GO:0050807 110 0.344
macromolecular complex assembly GO:0065003 256 0.340
morphogenesis of an epithelium GO:0002009 276 0.340
intracellular mrna localization involved in anterior posterior axis specification GO:0060811 53 0.336
purine nucleotide catabolic process GO:0006195 109 0.324
Human Yeast Mouse Worm
regulation of protein dephosphorylation GO:0035304 5 0.324
appendage morphogenesis GO:0035107 397 0.322
regulation of epithelial cell proliferation GO:0050678 4 0.316
establishment of imaginal disc derived wing hair orientation GO:0001737 24 0.315
secretion by cell GO:0032940 101 0.314
Human Worm
branching involved in open tracheal system development GO:0060446 45 0.313
membrane invagination GO:0010324 11 0.313
myoblast proliferation GO:0051450 3 0.307
asymmetric protein localization GO:0008105 33 0.300
Worm
chemotaxis GO:0006935 249 0.298
cell projection assembly GO:0030031 94 0.291
Human
purine nucleoside catabolic process GO:0006152 112 0.289
Human Yeast Mouse Worm
positive regulation of protein serine threonine kinase activity GO:0071902 15 0.288
dendrite morphogenesis GO:0048813 199 0.288
positive regulation of cell communication GO:0010647 250 0.288
body morphogenesis GO:0010171 2 0.287
purine nucleoside monophosphate metabolic process GO:0009126 50 0.285
regulation of mapk cascade GO:0043408 92 0.283
regulation of cell death GO:0010941 173 0.279
filopodium assembly GO:0046847 33 0.277
Human
maintenance of cell polarity GO:0030011 18 0.275
positive regulation of secretion by cell GO:1903532 20 0.273
Human
purine ribonucleotide catabolic process GO:0009154 109 0.267
Human Yeast Mouse Worm
phagocytosis engulfment GO:0006911 11 0.267
response to inorganic substance GO:0010035 44 0.265
imaginal disc derived wing hair organization GO:0035317 45 0.262
developmental growth GO:0048589 280 0.261
cell growth GO:0016049 108 0.261
regulation of cell morphogenesis involved in differentiation GO:0010769 61 0.259
centrosome cycle GO:0007098 137 0.258
cellular response to external stimulus GO:0071496 66 0.257
embryonic morphogenesis GO:0048598 206 0.253
signal transduction by phosphorylation GO:0023014 107 0.250
negative regulation of signal transduction GO:0009968 206 0.248
regulation of actin filament length GO:0030832 27 0.244
imaginal disc derived wing hair site selection GO:0035320 4 0.244
positive regulation of cell death GO:0010942 69 0.244
molting cycle GO:0042303 56 0.243
Worm
macromolecule catabolic process GO:0009057 161 0.242
Worm
actin cytoskeleton organization GO:0030036 206 0.239
positive regulation of exocytosis GO:0045921 4 0.239
Human
dorsal closure GO:0007391 79 0.239
positive regulation of cell proliferation GO:0008284 47 0.238
response to starvation GO:0042594 97 0.238
membrane budding GO:0006900 4 0.238
synaptic vesicle endocytosis GO:0048488 28 0.238
regulation of multi organism process GO:0043900 131 0.236
endomembrane system organization GO:0010256 119 0.233
Yeast Mouse
synaptic vesicle localization GO:0097479 53 0.231
cell junction organization GO:0034330 57 0.230
intracellular signal transduction GO:0035556 300 0.219
establishment of neuroblast polarity GO:0045200 2 0.218
regulation of nervous system development GO:0051960 248 0.218
pole plasm oskar mrna localization GO:0045451 46 0.218
small molecule metabolic process GO:0044281 305 0.215
Human Yeast Mouse Worm
non sensory hair organization GO:0035316 47 0.214
border follicle cell migration GO:0007298 113 0.212
stem cell differentiation GO:0048863 117 0.209
positive regulation of macromolecule biosynthetic process GO:0010557 283 0.208
dendrite development GO:0016358 204 0.208
embryo development ending in birth or egg hatching GO:0009792 152 0.208
circulatory system development GO:0072359 82 0.205
Zebrafish
anatomical structure homeostasis GO:0060249 97 0.199
blastoderm segmentation GO:0007350 159 0.198
organophosphate metabolic process GO:0019637 195 0.198
Human Yeast Mouse Worm
compound eye development GO:0048749 307 0.197
regulation of neurogenesis GO:0050767 158 0.196
digestive system development GO:0055123 149 0.196
Zebrafish
positive regulation of phosphorylation GO:0042327 87 0.189
nucleoside triphosphate catabolic process GO:0009143 108 0.188
Human Yeast Mouse Worm
regulation of neuron projection development GO:0010975 69 0.187
cation homeostasis GO:0055080 51 0.183
regulation of phosphorus metabolic process GO:0051174 210 0.183
respiratory system development GO:0060541 213 0.183
meiotic cell cycle process GO:1903046 132 0.183
appendage development GO:0048736 401 0.181
positive regulation of cellular biosynthetic process GO:0031328 316 0.180
establishment or maintenance of microtubule cytoskeleton polarity GO:0030951 41 0.180
pole plasm assembly GO:0007315 61 0.179
regulation of kinase activity GO:0043549 53 0.177
nucleoside phosphate catabolic process GO:1901292 110 0.177
Human Yeast Mouse Worm
synaptic vesicle exocytosis GO:0016079 16 0.176
Human
single organism behavior GO:0044708 391 0.176
cellular protein complex assembly GO:0043623 71 0.174
cellular response to chemical stimulus GO:0070887 199 0.174
response to transforming growth factor beta GO:0071559 18 0.174
stem cell development GO:0048864 79 0.174
regulation of cell cycle GO:0051726 291 0.173
positive regulation of protein phosphorylation GO:0001934 34 0.173
intracellular mrna localization GO:0008298 66 0.172
regulation of neuron differentiation GO:0045664 103 0.172
growth GO:0040007 359 0.170
regulation of molecular function GO:0065009 217 0.170
positive regulation of protein modification process GO:0031401 58 0.169
chromosome segregation GO:0007059 157 0.169
cytokinesis GO:0000910 90 0.168
Worm
hair cell differentiation GO:0035315 47 0.166
regulation of response to stress GO:0080134 200 0.164
dorsal appendage formation GO:0046843 47 0.164
organic substance catabolic process GO:1901575 308 0.164
Human Yeast Mouse Worm
defense response to other organism GO:0098542 225 0.163
regulation of secretion by cell GO:1903530 39 0.163
Human
negative regulation of cell communication GO:0010648 223 0.162
positive regulation of phosphorus metabolic process GO:0010562 139 0.162
multicellular organismal homeostasis GO:0048871 41 0.160
wing disc morphogenesis GO:0007472 344 0.157
engulfment of apoptotic cell GO:0043652 6 0.156
maintenance of protein location GO:0045185 28 0.154
purine ribonucleoside triphosphate catabolic process GO:0009207 108 0.154
Human Yeast Mouse Worm
epidermal growth factor receptor signaling pathway GO:0007173 58 0.150
regulation of transport GO:0051049 181 0.150
organonitrogen compound metabolic process GO:1901564 318 0.149
Human Yeast Mouse Worm
negative regulation of synaptic growth at neuromuscular junction GO:0045886 39 0.149
positive regulation of cellular protein metabolic process GO:0032270 118 0.146
digestive tract morphogenesis GO:0048546 127 0.141
Zebrafish
establishment of spindle localization GO:0051293 22 0.139
chemical homeostasis GO:0048878 92 0.138
carbohydrate derivative catabolic process GO:1901136 118 0.137
Human Yeast Mouse Worm
stress activated mapk cascade GO:0051403 52 0.136
nucleus localization GO:0051647 34 0.136
spermatid differentiation GO:0048515 114 0.136
adherens junction maintenance GO:0034334 9 0.136
larval development GO:0002164 104 0.136
Worm
asymmetric stem cell division GO:0098722 49 0.135
dorsal closure elongation of leading edge cells GO:0007394 10 0.133
erbb signaling pathway GO:0038127 58 0.133
negative regulation of cellular component organization GO:0051129 108 0.132
cell adhesion GO:0007155 136 0.131
Zebrafish
cellular ion homeostasis GO:0006873 39 0.130
purine ribonucleotide metabolic process GO:0009150 145 0.130
Human Yeast Mouse Worm
early endosome to late endosome transport GO:0045022 3 0.128
Human
cytoplasmic transport GO:0016482 130 0.127
developmental growth involved in morphogenesis GO:0060560 65 0.127
regulation of protein serine threonine kinase activity GO:0071900 25 0.126
head development GO:0060322 135 0.126
positive regulation of phosphate metabolic process GO:0045937 139 0.125
positive regulation of response to stimulus GO:0048584 323 0.125
metal ion homeostasis GO:0055065 44 0.124
establishment or maintenance of bipolar cell polarity GO:0061245 34 0.124
chorion containing eggshell formation GO:0007304 105 0.124
proteolysis GO:0006508 192 0.123
neuron projection guidance GO:0097485 241 0.123
regulation of tube architecture open tracheal system GO:0035152 68 0.123
cortical cytoskeleton organization GO:0030865 29 0.121
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 65 0.121
negative regulation of cellular metabolic process GO:0031324 382 0.121
regulation of cell differentiation GO:0045595 302 0.121
modification dependent macromolecule catabolic process GO:0043632 79 0.120
cytoskeleton dependent cytokinesis GO:0061640 81 0.119
programmed cell death GO:0012501 257 0.119
Worm
positive regulation of organelle organization GO:0010638 65 0.118
purine nucleotide metabolic process GO:0006163 146 0.117
Human Yeast Mouse Worm
somatic stem cell division GO:0048103 37 0.116
single organism cell adhesion GO:0098602 47 0.115
Zebrafish
open tracheal system development GO:0007424 204 0.115
regulation of programmed cell death GO:0043067 152 0.113
autophagic vacuole assembly GO:0000045 2 0.112
response to growth factor GO:0070848 31 0.112
regulation of actin cytoskeleton organization GO:0032956 42 0.112
endosome organization GO:0007032 9 0.111
Yeast Mouse
embryonic ectodermal digestive tract development GO:0048611 4 0.111
gastrulation GO:0007369 70 0.107
Zebrafish
protein localization to membrane GO:0072657 19 0.107
regulation of cellular localization GO:0060341 136 0.106
Human
actin filament based process GO:0030029 220 0.106
regulation of microtubule cytoskeleton organization GO:0070507 41 0.103
positive regulation of protein metabolic process GO:0051247 128 0.103
cellular catabolic process GO:0044248 372 0.102
Human Yeast Mouse Worm
purine ribonucleoside catabolic process GO:0046130 112 0.101
Human Yeast Mouse Worm
purine containing compound catabolic process GO:0072523 112 0.100
Human Yeast Mouse Worm
epithelial tube morphogenesis GO:0060562 88 0.100
positive regulation of mapk cascade GO:0043410 63 0.100
cell fate determination GO:0001709 91 0.099
gland morphogenesis GO:0022612 145 0.098
single organism catabolic process GO:0044712 228 0.097
Human Yeast Mouse Worm
nucleoside monophosphate metabolic process GO:0009123 52 0.096
dorsal closure spreading of leading edge cells GO:0007395 4 0.096
digestive tract development GO:0048565 149 0.095
Zebrafish
regulation of cellular response to stress GO:0080135 89 0.094
ubiquitin dependent protein catabolic process GO:0006511 78 0.092
positive regulation of cell motility GO:2000147 3 0.092
spindle localization GO:0051653 22 0.092
regulation of multicellular organismal development GO:2000026 414 0.092
cellular protein catabolic process GO:0044257 83 0.090
positive regulation of intracellular signal transduction GO:1902533 116 0.090
neuron remodeling GO:0016322 29 0.089
organelle assembly GO:0070925 198 0.087
Yeast
establishment of spindle orientation GO:0051294 18 0.087
receptor mediated endocytosis GO:0006898 21 0.086
Human Worm
negative regulation of erbb signaling pathway GO:1901185 29 0.085
regulation of anatomical structure size GO:0090066 163 0.084
Human
unidimensional cell growth GO:0009826 15 0.084
aromatic compound catabolic process GO:0019439 166 0.083
Human Yeast Mouse Worm
regulation of actin filament based process GO:0032970 42 0.083
oxoacid metabolic process GO:0043436 103 0.082
organic substance transport GO:0071702 257 0.082
Yeast Worm
detection of stimulus GO:0051606 156 0.082
purine nucleoside triphosphate catabolic process GO:0009146 108 0.081
Human Yeast Mouse Worm
cell death GO:0008219 279 0.081
Worm
gliogenesis GO:0042063 80 0.081
hemocyte migration GO:0035099 19 0.081
regulation of protein ubiquitination GO:0031396 22 0.080
pole plasm rna localization GO:0007316 52 0.080
regulation of notch signaling pathway GO:0008593 100 0.080
stem cell proliferation GO:0072089 88 0.079
regulation of response to wounding GO:1903034 19 0.078
cellularization GO:0007349 90 0.077
single organism carbohydrate metabolic process GO:0044723 72 0.077
regulation of tube length open tracheal system GO:0035159 24 0.077
guanosine containing compound catabolic process GO:1901069 74 0.076
Human Yeast Mouse Worm
nuclear division GO:0000280 332 0.076
neuron recognition GO:0008038 101 0.076
negative regulation of phosphate metabolic process GO:0045936 45 0.075
regionalization GO:0003002 416 0.075
morphogenesis of embryonic epithelium GO:0016331 94 0.075
negative regulation of growth GO:0045926 84 0.075
regulation of cell motility GO:2000145 23 0.075
regulation of transferase activity GO:0051338 58 0.074
purine nucleoside metabolic process GO:0042278 127 0.072
Human Yeast Mouse Worm
protein modification by small protein conjugation or removal GO:0070647 106 0.071
cellular response to growth factor stimulus GO:0071363 30 0.071
regulation of jnk cascade GO:0046328 40 0.071
stress activated protein kinase signaling cascade GO:0031098 55 0.070
ion transport GO:0006811 145 0.067
cellular cation homeostasis GO:0030003 38 0.067
sensory perception of chemical stimulus GO:0007606 116 0.067
regulation of catabolic process GO:0009894 170 0.067
nucleotide catabolic process GO:0009166 109 0.066
Human Yeast Mouse Worm
imaginal disc derived appendage morphogenesis GO:0035114 395 0.066
cellular macromolecular complex assembly GO:0034622 153 0.066
anterior midgut ectodermal morphogenesis GO:0007441 4 0.066
death GO:0016265 284 0.065
Worm
segmentation GO:0035282 207 0.065
energy derivation by oxidation of organic compounds GO:0015980 32 0.065
regulation of cell cycle phase transition GO:1901987 130 0.064
proteolysis involved in cellular protein catabolic process GO:0051603 83 0.064
regulation of stress activated protein kinase signaling cascade GO:0070302 42 0.064
regulation of secretion GO:0051046 44 0.064
Human
regulation of cell cell adhesion GO:0022407 21 0.063
fertilization GO:0009566 26 0.062
regulation of locomotion GO:0040012 42 0.062
glial cell migration GO:0008347 31 0.061
modification dependent protein catabolic process GO:0019941 78 0.060
regulation of mitotic cell cycle GO:0007346 190 0.060
negative regulation of cell differentiation GO:0045596 143 0.060
dephosphorylation GO:0016311 51 0.060
cellular carbohydrate metabolic process GO:0044262 22 0.060
neuron maturation GO:0042551 31 0.060
positive regulation of endocytosis GO:0045807 22 0.060
regulation of mitotic cell cycle phase transition GO:1901990 130 0.059
maternal determination of anterior posterior axis embryo GO:0008358 74 0.059
regulation of protein complex assembly GO:0043254 42 0.058
positive regulation of gene expression GO:0010628 290 0.058
response to nutrient levels GO:0031667 114 0.057
spermatid development GO:0007286 98 0.057
epithelial cell proliferation GO:0050673 15 0.057
response to endogenous stimulus GO:0009719 119 0.057
autophagy GO:0006914 108 0.057
mitotic cytokinesis GO:0000281 50 0.057
regulation of epithelial cell migration GO:0010632 12 0.056
actin filament organization GO:0007015 126 0.056
establishment of vesicle localization GO:0051650 51 0.055
positive regulation of secretion GO:0051047 22 0.055
Human
imaginal disc derived appendage development GO:0048737 399 0.055
positive regulation of protein localization to plasma membrane GO:1903078 3 0.055
eggshell formation GO:0030703 105 0.054
purine containing compound metabolic process GO:0072521 155 0.054
Human Yeast Mouse Worm
neuron death GO:0070997 27 0.054
epidermal cell differentiation GO:0009913 51 0.054
carbohydrate derivative metabolic process GO:1901135 217 0.054
Human Yeast Mouse Worm
purine ribonucleoside triphosphate metabolic process GO:0009205 119 0.053
Human Yeast Mouse Worm
carbohydrate metabolic process GO:0005975 82 0.053
photoreceptor cell development GO:0042461 96 0.053
gtp catabolic process GO:0006184 72 0.053
Human Yeast Mouse Worm
erk1 and erk2 cascade GO:0070371 39 0.052
maintenance of apical basal cell polarity GO:0035090 8 0.052
negative regulation of intracellular signal transduction GO:1902532 57 0.052
positive regulation of programmed cell death GO:0043068 62 0.051
regulation of actin filament polymerization GO:0030833 25 0.051
nucleoside metabolic process GO:0009116 127 0.051
Human Yeast Mouse Worm
regulation of neuromuscular synaptic transmission GO:1900073 15 0.051
morphogenesis of a branching epithelium GO:0061138 45 0.050
salivary gland morphogenesis GO:0007435 145 0.050
rho protein signal transduction GO:0007266 14 0.050
regulation of embryonic development GO:0045995 68 0.050
negative regulation of mitotic cell cycle GO:0045930 109 0.050
anterior posterior axis specification GO:0009948 109 0.050
response to other organism GO:0051707 293 0.049
regulation of catalytic activity GO:0050790 185 0.049
small gtpase mediated signal transduction GO:0007264 88 0.048
positive regulation of cell adhesion GO:0045785 10 0.048
phagocytosis GO:0006909 215 0.048
Worm
protein localization to plasma membrane GO:0072659 13 0.047
membrane tubulation GO:0097320 4 0.047
response to biotic stimulus GO:0009607 294 0.047
mesoderm development GO:0007498 78 0.046
establishment of nucleus localization GO:0040023 26 0.046
intracellular mrna localization involved in pattern specification process GO:0060810 56 0.046
regulation of developmental growth GO:0048638 174 0.046
formation of anatomical boundary GO:0048859 37 0.046
micropyle formation GO:0046844 4 0.046
photoreceptor cell differentiation GO:0046530 170 0.046
developmental cell growth GO:0048588 52 0.045
spermatogenesis GO:0007283 200 0.044
regulation of dna metabolic process GO:0051052 34 0.044
organelle fission GO:0048285 340 0.044
ribonucleotide metabolic process GO:0009259 145 0.044
Human Yeast Mouse Worm
positive regulation of cellular amino acid metabolic process GO:0045764 0 0.043
central nervous system development GO:0007417 201 0.043
ubiquitin dependent protein catabolic process via the multivesicular body sorting pathway GO:0043162 8 0.043
negative regulation of cellular biosynthetic process GO:0031327 277 0.043
cell activation GO:0001775 9 0.043
cellular divalent inorganic cation homeostasis GO:0072503 23 0.043
embryonic ectodermal digestive tract morphogenesis GO:0048613 4 0.042
maintenance of protein location in cell GO:0032507 26 0.042
maintenance of location GO:0051235 73 0.042
Worm
establishment of proximal distal cell polarity GO:0022606 4 0.042
regulation of map kinase activity GO:0043405 17 0.041
negative regulation of phosphorus metabolic process GO:0010563 45 0.041
positive regulation of transferase activity GO:0051347 26 0.041
mitotic spindle organization GO:0007052 220 0.041

Rab5 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

Disease DO term ID Size Probability Func Analog Org
neuromuscular disease DOID:440 0 0.058
disease of anatomical entity DOID:7 0 0.058
nervous system disease DOID:863 0 0.058
neuropathy DOID:870 0 0.058
charcot marie tooth disease DOID:10595 0 0.048