Drosophila melanogaster

0 known processes

Sep4 (Dmel_CG9699)

Septin 4

(Aliases: sep4,CG9699,Dmel\CG9699)

Sep4 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
cellular catabolic process GO:0044248 372 0.156
organonitrogen compound catabolic process GO:1901565 128 0.123
negative regulation of gene expression GO:0010629 387 0.098
macromolecular complex assembly GO:0065003 256 0.085
organonitrogen compound metabolic process GO:1901564 318 0.084
purine ribonucleoside catabolic process GO:0046130 112 0.077
nucleoside phosphate metabolic process GO:0006753 162 0.074
positive regulation of peptidase activity GO:0010952 29 0.073
aromatic compound catabolic process GO:0019439 166 0.072
gene silencing GO:0016458 138 0.066
catabolic process GO:0009056 409 0.064
purine nucleoside catabolic process GO:0006152 112 0.062
nucleobase containing small molecule metabolic process GO:0055086 174 0.062
negative regulation of cellular metabolic process GO:0031324 382 0.061
small molecule metabolic process GO:0044281 305 0.060
compound eye development GO:0048749 307 0.059
protein heterooligomerization GO:0051291 4 0.058
pigment metabolic process GO:0042440 84 0.058
purine ribonucleoside triphosphate metabolic process GO:0009205 119 0.056
gtp metabolic process GO:0046039 72 0.054
organic substance catabolic process GO:1901575 308 0.053
regulation of gene expression epigenetic GO:0040029 128 0.051
glycosyl compound catabolic process GO:1901658 112 0.050
nucleobase containing compound catabolic process GO:0034655 165 0.049
developmental cell growth GO:0048588 52 0.049
heterocycle catabolic process GO:0046700 166 0.049
single organism catabolic process GO:0044712 228 0.048
ribonucleoside catabolic process GO:0042454 112 0.048
purine nucleotide catabolic process GO:0006195 109 0.047
ribonucleoside metabolic process GO:0009119 127 0.046
intracellular signal transduction GO:0035556 300 0.046
glycosyl compound metabolic process GO:1901657 127 0.046
nucleotide catabolic process GO:0009166 109 0.045
membrane organization GO:0061024 112 0.045
regulation of catabolic process GO:0009894 170 0.045
response to oxygen containing compound GO:1901700 200 0.045
regulation of anatomical structure morphogenesis GO:0022603 242 0.042
posttranscriptional gene silencing by rna GO:0035194 45 0.042
positive regulation of rna biosynthetic process GO:1902680 266 0.042
carbohydrate derivative catabolic process GO:1901136 118 0.041
biological adhesion GO:0022610 138 0.041
positive regulation of response to stimulus GO:0048584 323 0.040
regulation of cellular response to stress GO:0080135 89 0.040
eye morphogenesis GO:0048592 260 0.039
protein complex biogenesis GO:0070271 201 0.039
kidney development GO:0001822 3 0.039
regulation of molecular function GO:0065009 217 0.038
chromosome organization GO:0051276 360 0.038
single organism carbohydrate metabolic process GO:0044723 72 0.038
nucleoside catabolic process GO:0009164 112 0.038
response to alcohol GO:0097305 95 0.037
regulation of phosphorus metabolic process GO:0051174 210 0.037
purine ribonucleoside metabolic process GO:0046128 127 0.037
purine nucleoside triphosphate metabolic process GO:0009144 119 0.037
purine nucleoside triphosphate catabolic process GO:0009146 108 0.037
regulation of cellular amine metabolic process GO:0033238 3 0.036
guanosine containing compound metabolic process GO:1901068 74 0.036
purine ribonucleoside triphosphate catabolic process GO:0009207 108 0.036
positive regulation of nucleobase containing compound metabolic process GO:0045935 332 0.036
regulation of neurogenesis GO:0050767 158 0.036
activation of cysteine type endopeptidase activity GO:0097202 17 0.035
ribonucleotide catabolic process GO:0009261 109 0.035
response to ethanol GO:0045471 59 0.035
nuclear division GO:0000280 332 0.035
organic acid metabolic process GO:0006082 103 0.035
establishment of protein localization GO:0045184 163 0.034
positive regulation of molecular function GO:0044093 136 0.034
protein localization to organelle GO:0033365 82 0.034
positive regulation of cellular catabolic process GO:0031331 95 0.034
nucleoside phosphate catabolic process GO:1901292 110 0.033
regulation of cell death GO:0010941 173 0.033
regulation of cellular amino acid metabolic process GO:0006521 0 0.032
ribonucleotide metabolic process GO:0009259 145 0.031
compound eye morphogenesis GO:0001745 249 0.031
response to organic substance GO:0010033 284 0.031
purine containing compound catabolic process GO:0072523 112 0.031
single organism cellular localization GO:1902580 180 0.031
eye development GO:0001654 323 0.031
regulation of localization GO:0032879 275 0.031
regulation of cellular ketone metabolic process GO:0010565 3 0.031
purine nucleoside metabolic process GO:0042278 127 0.031
protein localization GO:0008104 284 0.030
organic cyclic compound catabolic process GO:1901361 168 0.030
regulation of cellular catabolic process GO:0031329 157 0.030
oxoacid metabolic process GO:0043436 103 0.030
cellular response to chemical stimulus GO:0070887 199 0.030
cellular response to starvation GO:0009267 61 0.030
positive regulation of cellular biosynthetic process GO:0031328 316 0.030
cellular protein modification process GO:0006464 438 0.030
neurological system process GO:0050877 358 0.029
gtp catabolic process GO:0006184 72 0.029
guanosine containing compound catabolic process GO:1901069 74 0.029
regulation of protein metabolic process GO:0051246 256 0.029
cellular nitrogen compound catabolic process GO:0044270 165 0.028
ribonucleoside triphosphate catabolic process GO:0009203 108 0.028
nucleoside metabolic process GO:0009116 127 0.028
positive regulation of catabolic process GO:0009896 105 0.028
regulation of anatomical structure size GO:0090066 163 0.028
posttranscriptional gene silencing GO:0016441 46 0.027
endomembrane system organization GO:0010256 119 0.027
autophagy GO:0006914 108 0.026
carbohydrate derivative metabolic process GO:1901135 217 0.026
purine containing compound metabolic process GO:0072521 155 0.026
protein complex assembly GO:0006461 200 0.026
nucleoside triphosphate catabolic process GO:0009143 108 0.026
ribonucleoside triphosphate metabolic process GO:0009199 119 0.026
amine metabolic process GO:0009308 12 0.026
multi organism reproductive behavior GO:0044705 121 0.026
regulation of intracellular signal transduction GO:1902531 236 0.025
chromosome segregation GO:0007059 157 0.025
nucleoside triphosphate metabolic process GO:0009141 120 0.025
forebrain development GO:0030900 2 0.024
posttranscriptional regulation of gene expression GO:0010608 145 0.024
positive regulation of hydrolase activity GO:0051345 78 0.024
negative regulation of cell communication GO:0010648 223 0.024
carboxylic acid metabolic process GO:0019752 92 0.024
sensory organ morphogenesis GO:0090596 260 0.024
regulation of ras gtpase activity GO:0032318 38 0.024
protein transport GO:0015031 155 0.023
positive regulation of nitrogen compound metabolic process GO:0051173 354 0.023
purine nucleotide metabolic process GO:0006163 146 0.023
body morphogenesis GO:0010171 2 0.023
appendage development GO:0048736 401 0.023
homeostatic process GO:0042592 199 0.023
cation transmembrane transport GO:0098655 88 0.023
neuron projection extension GO:1990138 32 0.023
death GO:0016265 284 0.023
intracellular protein transport GO:0006886 104 0.022
regulation of phosphate metabolic process GO:0019220 210 0.022
spindle organization GO:0007051 253 0.022
intracellular transport GO:0046907 228 0.022
positive regulation of phosphorus metabolic process GO:0010562 139 0.022
organic substance transport GO:0071702 257 0.022
cytoplasmic transport GO:0016482 130 0.022
proteolysis GO:0006508 192 0.022
cellular amino acid metabolic process GO:0006520 61 0.022
protein modification process GO:0036211 438 0.022
gene silencing by rna GO:0031047 57 0.022
response to hexose GO:0009746 3 0.021
macromolecule catabolic process GO:0009057 161 0.021
lateral inhibition GO:0046331 206 0.021
cell death GO:0008219 279 0.021
nucleotide metabolic process GO:0009117 161 0.021
regulation of cellular protein metabolic process GO:0032268 243 0.021
mitotic dna integrity checkpoint GO:0044774 75 0.021
protein maturation GO:0051604 71 0.021
negative regulation of cell cycle phase transition GO:1901988 103 0.021
cellular ketone metabolic process GO:0042180 24 0.021
purine ribonucleotide metabolic process GO:0009150 145 0.021
protein localization to nucleus GO:0034504 55 0.021
phagocytosis GO:0006909 215 0.020
organophosphate catabolic process GO:0046434 112 0.020
positive regulation of jun kinase activity GO:0043507 4 0.020
immune system process GO:0002376 347 0.020
carbohydrate metabolic process GO:0005975 82 0.020
cellular amine metabolic process GO:0044106 12 0.020
microtubule organizing center organization GO:0031023 168 0.020
regulation of gtpase activity GO:0043087 44 0.020
cell adhesion GO:0007155 136 0.020
positive regulation of macromolecule metabolic process GO:0010604 405 0.020
single organism behavior GO:0044708 391 0.020
vesicle mediated transport GO:0016192 381 0.020
cell proliferation GO:0008283 299 0.020
spermatid development GO:0007286 98 0.020
regulation of catalytic activity GO:0050790 185 0.020
developmental growth GO:0048589 280 0.019
jnk cascade GO:0007254 50 0.019
regulation of neuron differentiation GO:0045664 103 0.019
positive regulation of biosynthetic process GO:0009891 316 0.019
purine ribonucleotide catabolic process GO:0009154 109 0.019
cellular macromolecule localization GO:0070727 220 0.019
cellular response to dna damage stimulus GO:0006974 223 0.019
imaginal disc derived appendage development GO:0048737 399 0.019
regulation of proteolysis GO:0030162 87 0.019
camera type eye development GO:0043010 4 0.018
establishment of localization in cell GO:0051649 402 0.018
organophosphate metabolic process GO:0019637 195 0.018
regulation of transport GO:0051049 181 0.018
response to organophosphorus GO:0046683 2 0.018
chromatin modification GO:0016568 147 0.018
covalent chromatin modification GO:0016569 106 0.018
response to lipopolysaccharide GO:0032496 4 0.018
cellular protein localization GO:0034613 160 0.017
single organism intracellular transport GO:1902582 207 0.017
mitotic cell cycle phase transition GO:0044772 138 0.017
l amino acid import GO:0043092 2 0.017
cell cell signaling involved in cell fate commitment GO:0045168 210 0.017
positive regulation of cellular amino acid metabolic process GO:0045764 0 0.017
endosomal transport GO:0016197 44 0.017
multi organism behavior GO:0051705 175 0.017
imaginal disc derived appendage morphogenesis GO:0035114 395 0.017
regulation of autophagy GO:0010506 62 0.017
golgi organization GO:0007030 66 0.017
negative regulation of cell death GO:0060548 81 0.017
mapk cascade GO:0000165 107 0.017
positive regulation of signaling GO:0023056 243 0.017
chromatin silencing GO:0006342 76 0.017
regulation of hydrolase activity GO:0051336 97 0.016
positive regulation of autophagy GO:0010508 21 0.016
erbb signaling pathway GO:0038127 58 0.016
regulation of cell development GO:0060284 215 0.016
actin filament based movement GO:0030048 26 0.016
response to starvation GO:0042594 97 0.016
regulation of macroautophagy GO:0016241 15 0.016
positive regulation of cell communication GO:0010647 250 0.016
regulation of cell differentiation GO:0045595 302 0.016
protein processing GO:0016485 68 0.016
cilium morphogenesis GO:0060271 39 0.016
small gtpase mediated signal transduction GO:0007264 88 0.016
enzyme linked receptor protein signaling pathway GO:0007167 179 0.016
protein modification by small protein conjugation or removal GO:0070647 106 0.016
reproductive behavior GO:0019098 122 0.016
mitotic dna damage checkpoint GO:0044773 74 0.016
regulation of ras protein signal transduction GO:0046578 93 0.015
regulation of actin filament based process GO:0032970 42 0.015
regulation of organelle organization GO:0033043 196 0.015
protein import into nucleus GO:0006606 51 0.015
positive regulation of catalytic activity GO:0043085 118 0.015
ras protein signal transduction GO:0007265 88 0.015
programmed cell death GO:0012501 257 0.015
positive regulation of intracellular signal transduction GO:1902533 116 0.015
rna processing GO:0006396 147 0.015
nucleus localization GO:0051647 34 0.015
cellular response to nutrient levels GO:0031669 62 0.015
gene silencing by mirna GO:0035195 22 0.015
execution phase of apoptosis GO:0097194 7 0.015
autophagic cell death GO:0048102 83 0.015
cellular homeostasis GO:0019725 80 0.014
positive regulation of cell death GO:0010942 69 0.014
cardiovascular system development GO:0072358 82 0.014
developmental programmed cell death GO:0010623 138 0.014
regulation of jnk cascade GO:0046328 40 0.014
positive regulation of transcription dna templated GO:0045893 266 0.014
response to monosaccharide GO:0034284 4 0.014
positive regulation of phosphate metabolic process GO:0045937 139 0.014
establishment of protein localization to organelle GO:0072594 62 0.014
sensory perception GO:0007600 196 0.014
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 116 0.013
chromatin organization GO:0006325 207 0.013
salivary gland cell autophagic cell death GO:0035071 83 0.013
axon extension GO:0048675 32 0.013
compound eye photoreceptor cell differentiation GO:0001751 140 0.013
mitotic nuclear division GO:0007067 213 0.013
stress activated mapk cascade GO:0051403 52 0.013
cellular macromolecular complex assembly GO:0034622 153 0.013
peptidyl amino acid modification GO:0018193 105 0.013
imaginal disc derived wing morphogenesis GO:0007476 337 0.013
cellular response to external stimulus GO:0071496 66 0.013
response to radiation GO:0009314 155 0.013
adult behavior GO:0030534 137 0.013
positive regulation of proteolysis GO:0045862 52 0.013
positive regulation of macromolecule biosynthetic process GO:0010557 283 0.013
notch signaling pathway GO:0007219 120 0.013
positive regulation of purine nucleotide metabolic process GO:1900544 55 0.013
regulation of mitotic cell cycle GO:0007346 190 0.013
regulation of response to stress GO:0080134 200 0.013
smoothened signaling pathway GO:0007224 49 0.012
extracellular structure organization GO:0043062 46 0.012
morphogenesis of an epithelium GO:0002009 276 0.012
appendage morphogenesis GO:0035107 397 0.012
positive regulation of purine nucleotide catabolic process GO:0033123 46 0.012
negative regulation of mitotic cell cycle phase transition GO:1901991 103 0.012
wing disc morphogenesis GO:0007472 344 0.012
regulation of intracellular protein transport GO:0033157 46 0.012
positive regulation of signal transduction GO:0009967 223 0.012
sterol homeostasis GO:0055092 4 0.012
cytoskeleton dependent cytokinesis GO:0061640 81 0.012
tissue morphogenesis GO:0048729 297 0.012
brain development GO:0007420 120 0.012
protein dephosphorylation GO:0006470 27 0.012
cytokinesis GO:0000910 90 0.012
cell fate determination GO:0001709 91 0.012
signal transduction by phosphorylation GO:0023014 107 0.011
translation GO:0006412 69 0.011
proteolysis involved in cellular protein catabolic process GO:0051603 83 0.011
epidermal growth factor receptor signaling pathway GO:0007173 58 0.011
retina development in camera type eye GO:0060041 4 0.011
negative regulation of protein metabolic process GO:0051248 85 0.011
nucleocytoplasmic transport GO:0006913 72 0.011
centrosome organization GO:0051297 163 0.011
positive regulation of protein metabolic process GO:0051247 128 0.011
regulation of cellular component size GO:0032535 98 0.011
eye pigment granule organization GO:0008057 12 0.011
endocytosis GO:0006897 310 0.011
macroautophagy GO:0016236 42 0.011
ovarian follicle cell development GO:0030707 248 0.011
spermatogenesis GO:0007283 200 0.011
salivary gland histolysis GO:0035070 88 0.011
single organism membrane organization GO:0044802 93 0.011
columnar cuboidal epithelial cell development GO:0002066 249 0.011
regulation of nucleoside metabolic process GO:0009118 50 0.011
central nervous system development GO:0007417 201 0.011
regulation of small gtpase mediated signal transduction GO:0051056 93 0.011
regulation of protein localization GO:0032880 76 0.011
positive regulation of cell motility GO:2000147 3 0.011
defense response GO:0006952 300 0.011
membrane depolarization GO:0051899 4 0.011
asymmetric cell division GO:0008356 37 0.011
negative regulation of cellular protein metabolic process GO:0032269 85 0.010
positive regulation of cellular amine metabolic process GO:0033240 0 0.010
rho protein signal transduction GO:0007266 14 0.010
sensory perception of chemical stimulus GO:0007606 116 0.010
cellular response to mechanical stimulus GO:0071260 2 0.010
hormone catabolic process GO:0042447 3 0.010
response to endogenous stimulus GO:0009719 119 0.010
regulation of mapk cascade GO:0043408 92 0.010
regulation of establishment of protein localization GO:0070201 61 0.010
cellular response to oxygen containing compound GO:1901701 79 0.010
regulation of programmed cell death GO:0043067 152 0.010
retinal cell programmed cell death GO:0046666 25 0.010
cellular response to organic cyclic compound GO:0071407 32 0.010
positive regulation of cellular component organization GO:0051130 156 0.010
nucleus organization GO:0006997 45 0.010
negative regulation of cell cycle process GO:0010948 109 0.010
response to glucose GO:0009749 2 0.010
maintenance of protein location in cell GO:0032507 26 0.010
negative regulation of rna metabolic process GO:0051253 251 0.010
regulation of apoptotic process GO:0042981 130 0.010
establishment of tissue polarity GO:0007164 87 0.010
cellular response to extracellular stimulus GO:0031668 64 0.010
post embryonic appendage morphogenesis GO:0035120 385 0.010

Sep4 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.040
disease of metabolism DOID:0014667 0 0.029
acquired metabolic disease DOID:0060158 0 0.029
cardiovascular system disease DOID:1287 0 0.028
nervous system disease DOID:863 0 0.023
sensory system disease DOID:0050155 0 0.020
disease of cellular proliferation DOID:14566 0 0.017
cancer DOID:162 0 0.017
inherited metabolic disorder DOID:655 0 0.017
carbohydrate metabolism disease DOID:0050013 0 0.014
diabetes mellitus DOID:9351 0 0.014
glucose metabolism disease DOID:4194 0 0.014
type 2 diabetes mellitus DOID:9352 0 0.014
organ system cancer DOID:0050686 0 0.014
eye and adnexa disease DOID:1492 0 0.012
eye disease DOID:5614 0 0.012
urinary system disease DOID:18 0 0.011