Drosophila melanogaster

168 known processes

dom (Dmel_CG9696)

domino

(Aliases: p400,Dom,DomA,Dmel\CG9696,CG9696,anon-WO0172774.190,l(2)81/8,27/4,l(2)k02704,l(2)k08108)

dom biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
dendrite development GO:0016358 204 1.000
regulation of transcription from rna polymerase ii promoter GO:0006357 378 0.993
immune system process GO:0002376 347 0.989
dendrite morphogenesis GO:0048813 199 0.981
gland development GO:0048732 191 0.949
positive regulation of transcription from rna polymerase ii promoter GO:0045944 204 0.914
negative regulation of rna biosynthetic process GO:1902679 240 0.905
positive regulation of macromolecule biosynthetic process GO:0010557 283 0.899
response to biotic stimulus GO:0009607 294 0.888
axonogenesis GO:0007409 290 0.886
axon development GO:0061564 297 0.845
negative regulation of macromolecule biosynthetic process GO:0010558 270 0.835
positive regulation of transcription dna templated GO:0045893 266 0.825
transcription from rna polymerase ii promoter GO:0006366 368 0.824
death GO:0016265 284 0.819
multi organism reproductive behavior GO:0044705 121 0.810
response to external biotic stimulus GO:0043207 293 0.802
peptidyl lysine modification GO:0018205 57 0.760
negative regulation of cellular biosynthetic process GO:0031327 277 0.716
response to organic cyclic compound GO:0014070 89 0.700
endocytosis GO:0006897 310 0.693
positive regulation of rna metabolic process GO:0051254 271 0.653
negative regulation of neuroblast proliferation GO:0007406 27 0.625
regulation of dendrite development GO:0050773 37 0.617
meiotic cell cycle process GO:1903046 132 0.611
localization of cell GO:0051674 257 0.610
negative regulation of transcription dna templated GO:0045892 237 0.602
regulation of multicellular organismal development GO:2000026 414 0.592
cellular protein modification process GO:0006464 438 0.590
cell motility GO:0048870 251 0.584
covalent chromatin modification GO:0016569 106 0.581
positive regulation of nucleic acid templated transcription GO:1903508 266 0.574
regulation of cell differentiation GO:0045595 302 0.571
negative regulation of nucleobase containing compound metabolic process GO:0045934 261 0.545
neuron projection guidance GO:0097485 241 0.542
positive regulation of rna biosynthetic process GO:1902680 266 0.541
maintenance of location GO:0051235 73 0.536
chromosome organization GO:0051276 360 0.531
positive regulation of nitrogen compound metabolic process GO:0051173 354 0.514
negative regulation of nitrogen compound metabolic process GO:0051172 265 0.512
vesicle mediated transport GO:0016192 381 0.511
immune system development GO:0002520 57 0.510
hematopoietic or lymphoid organ development GO:0048534 57 0.507
appendage development GO:0048736 401 0.501
programmed cell death GO:0012501 257 0.499
multicellular organismal reproductive behavior GO:0033057 110 0.498
negative regulation of nucleic acid templated transcription GO:1903507 240 0.479
response to other organism GO:0051707 293 0.471
positive regulation of biosynthetic process GO:0009891 316 0.466
regulation of neuron differentiation GO:0045664 103 0.464
photoreceptor cell differentiation GO:0046530 170 0.464
positive regulation of cellular biosynthetic process GO:0031328 316 0.454
embryonic organ development GO:0048568 50 0.454
regionalization GO:0003002 416 0.451
regulation of dendrite morphogenesis GO:0048814 28 0.443
response to organic substance GO:0010033 284 0.429
multi organism behavior GO:0051705 175 0.410
regulation of gene expression epigenetic GO:0040029 128 0.409
histone modification GO:0016570 106 0.391
regulation of neurogenesis GO:0050767 158 0.384
compound eye photoreceptor cell differentiation GO:0001751 140 0.379
larval development GO:0002164 104 0.378
Worm
neuroblast proliferation GO:0007405 74 0.374
negative regulation of biosynthetic process GO:0009890 277 0.366
hemopoiesis GO:0030097 46 0.366
mitotic spindle organization GO:0007052 220 0.348
positive regulation of macromolecule metabolic process GO:0010604 405 0.343
lipid localization GO:0010876 54 0.342
cell migration GO:0016477 238 0.336
negative regulation of cellular macromolecule biosynthetic process GO:2000113 267 0.321
salivary gland morphogenesis GO:0007435 145 0.321
cell death GO:0008219 279 0.318
embryo development ending in birth or egg hatching GO:0009792 152 0.310
Worm
negative regulation of rna metabolic process GO:0051253 251 0.306
reproductive structure development GO:0048608 74 0.305
Worm
tube development GO:0035295 244 0.295
catabolic process GO:0009056 409 0.293
eye photoreceptor cell differentiation GO:0001754 145 0.290
gland morphogenesis GO:0022612 145 0.288
positive regulation of gene expression GO:0010628 290 0.284
protein acetylation GO:0006473 39 0.275
stem cell differentiation GO:0048863 117 0.270
negative regulation of gene expression GO:0010629 387 0.268
taxis GO:0042330 304 0.263
dendrite guidance GO:0070983 21 0.256
negative regulation of multicellular organismal process GO:0051241 142 0.256
response to bacterium GO:0009617 198 0.253
cellular response to extracellular stimulus GO:0031668 64 0.252
regulation of growth GO:0040008 233 0.249
defense response to bacterium GO:0042742 178 0.247
body morphogenesis GO:0010171 2 0.230
digestive system development GO:0055123 149 0.230
cellular response to organic cyclic compound GO:0071407 32 0.227
muscle structure development GO:0061061 224 0.225
imaginal disc pattern formation GO:0007447 91 0.223
wing disc pattern formation GO:0035222 66 0.218
regulation of photoreceptor cell differentiation GO:0046532 34 0.218
embryonic development via the syncytial blastoderm GO:0001700 148 0.216
dorsal ventral pattern formation GO:0009953 133 0.216
defense response to other organism GO:0098542 225 0.204
central nervous system development GO:0007417 201 0.203
response to oxygen containing compound GO:1901700 200 0.201
head development GO:0060322 135 0.199
phagocytosis GO:0006909 215 0.199
lipid storage GO:0019915 38 0.190
internal protein amino acid acetylation GO:0006475 38 0.185
negative regulation of developmental process GO:0051093 201 0.184
developmental programmed cell death GO:0010623 138 0.182
negative regulation of transcription from rna polymerase ii promoter GO:0000122 119 0.177
regulation of glial cell proliferation GO:0060251 11 0.166
posttranscriptional gene silencing by rna GO:0035194 45 0.162
imaginal disc derived wing morphogenesis GO:0007476 337 0.160
regulation of gene silencing GO:0060968 63 0.155
regulation of cell morphogenesis GO:0022604 163 0.153
dna damage checkpoint GO:0000077 78 0.149
gene silencing GO:0016458 138 0.149
rna processing GO:0006396 147 0.148
ncrna processing GO:0034470 30 0.146
response to endogenous stimulus GO:0009719 119 0.145
chemotaxis GO:0006935 249 0.144
nuclear division GO:0000280 332 0.142
ubiquitin dependent protein catabolic process GO:0006511 78 0.141
regulation of cell proliferation GO:0042127 163 0.138
cell cell signaling involved in cell fate commitment GO:0045168 210 0.134
imaginal disc derived appendage development GO:0048737 399 0.133
peptidyl amino acid modification GO:0018193 105 0.131
axon guidance GO:0007411 233 0.130
regulation of cellular localization GO:0060341 136 0.128
ribonucleoside triphosphate catabolic process GO:0009203 108 0.126
macromolecule methylation GO:0043414 45 0.124
rna localization GO:0006403 115 0.124
sex differentiation GO:0007548 81 0.122
Worm
protein modification by small protein conjugation or removal GO:0070647 106 0.119
tissue death GO:0016271 102 0.118
cellular response to dna damage stimulus GO:0006974 223 0.115
salivary gland cell autophagic cell death GO:0035071 83 0.113
salivary gland development GO:0007431 162 0.112
response to alcohol GO:0097305 95 0.111
apoptotic process GO:0006915 159 0.109
response to abiotic stimulus GO:0009628 341 0.105
cellular response to organic substance GO:0071310 132 0.103
organonitrogen compound biosynthetic process GO:1901566 117 0.103
regulation of programmed cell death GO:0043067 152 0.103
histolysis GO:0007559 102 0.101
stem cell proliferation GO:0072089 88 0.100
glycosyl compound catabolic process GO:1901658 112 0.100
stem cell development GO:0048864 79 0.100
protein modification by small protein conjugation GO:0032446 79 0.100
molting cycle GO:0042303 56 0.093
immune response GO:0006955 246 0.092
cell proliferation GO:0008283 299 0.091
negative regulation of gene expression epigenetic GO:0045814 77 0.090
organic substance transport GO:0071702 257 0.088
receptor mediated endocytosis GO:0006898 21 0.088
regulation of localization GO:0032879 275 0.085
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 54 0.081
multi multicellular organism process GO:0044706 123 0.080
response to lipopolysaccharide GO:0032496 4 0.080
cellular response to chemical stimulus GO:0070887 199 0.078
tube morphogenesis GO:0035239 191 0.078
chromatin organization GO:0006325 207 0.076
posttranscriptional regulation of gene expression GO:0010608 145 0.075
protein localization GO:0008104 284 0.072
ribonucleoprotein complex biogenesis GO:0022613 31 0.072
protein phosphorylation GO:0006468 169 0.071
wing disc morphogenesis GO:0007472 344 0.070
brain development GO:0007420 120 0.068
reproductive behavior GO:0019098 122 0.068
regulation of anatomical structure morphogenesis GO:0022603 242 0.066
positive regulation of immune response GO:0050778 63 0.065
regulation of neuron projection development GO:0010975 69 0.063
negative regulation of stem cell proliferation GO:2000647 30 0.063
lateral inhibition GO:0046331 206 0.063
stem cell maintenance GO:0019827 67 0.062
developmental growth GO:0048589 280 0.060
imaginal disc derived appendage morphogenesis GO:0035114 395 0.059
negative regulation of cell differentiation GO:0045596 143 0.059
organelle localization GO:0051640 148 0.058
organelle inheritance GO:0048308 2 0.058
meiotic cell cycle GO:0051321 171 0.058
establishment of protein localization GO:0045184 163 0.056
protein dna complex subunit organization GO:0071824 86 0.055
organonitrogen compound metabolic process GO:1901564 318 0.055
striated muscle cell differentiation GO:0051146 90 0.055
hair cell differentiation GO:0035315 47 0.054
morphogenesis of an epithelium GO:0002009 276 0.054
regulation of apoptotic process GO:0042981 130 0.051
regulation of intracellular transport GO:0032386 64 0.051
ribosome biogenesis GO:0042254 8 0.051
methylation GO:0032259 47 0.050
chromatin silencing GO:0006342 76 0.050
notch signaling pathway GO:0007219 120 0.050
compound eye photoreceptor development GO:0042051 78 0.049
oviposition GO:0018991 19 0.047
hindbrain development GO:0030902 2 0.046
enzyme linked receptor protein signaling pathway GO:0007167 179 0.046
chromosome segregation GO:0007059 157 0.046
regulation of sequence specific dna binding transcription factor activity GO:0051090 12 0.045
growth GO:0040007 359 0.044
ribonucleoprotein complex subunit organization GO:0071826 28 0.044
mitotic dna integrity checkpoint GO:0044774 75 0.044
rrna processing GO:0006364 3 0.044
negative regulation of intrinsic apoptotic signaling pathway GO:2001243 1 0.042
carbohydrate derivative catabolic process GO:1901136 118 0.042
jak stat cascade GO:0007259 49 0.041
proteolysis involved in cellular protein catabolic process GO:0051603 83 0.041
somatic stem cell division GO:0048103 37 0.040
post embryonic appendage morphogenesis GO:0035120 385 0.038
salivary gland histolysis GO:0035070 88 0.038
wnt signaling pathway GO:0016055 98 0.038
organic acid metabolic process GO:0006082 103 0.038
organic substance catabolic process GO:1901575 308 0.037
protein catabolic process GO:0030163 101 0.037
regulation of organ morphogenesis GO:2000027 78 0.037
intracellular transport GO:0046907 228 0.037
tissue morphogenesis GO:0048729 297 0.036
glial cell proliferation GO:0014009 13 0.035
multicellular organismal aging GO:0010259 140 0.035
respiratory system development GO:0060541 213 0.035
modification dependent macromolecule catabolic process GO:0043632 79 0.035
meiotic nuclear division GO:0007126 151 0.034
male gamete generation GO:0048232 201 0.034
gonad development GO:0008406 50 0.033
Worm
muscle organ development GO:0007517 127 0.032
regulation of cell death GO:0010941 173 0.031
cellular response to external stimulus GO:0071496 66 0.031
positive regulation of response to stimulus GO:0048584 323 0.031
compound eye morphogenesis GO:0001745 249 0.031
gene silencing by rna GO:0031047 57 0.030
dna integrity checkpoint GO:0031570 81 0.030
response to organonitrogen compound GO:0010243 75 0.029
nucleocytoplasmic transport GO:0006913 72 0.029
development of primary sexual characteristics GO:0045137 50 0.029
Worm
exocrine system development GO:0035272 162 0.029
cellular catabolic process GO:0044248 372 0.029
nuclear transport GO:0051169 72 0.029
cellular response to amino acid starvation GO:0034198 7 0.028
regulation of nervous system development GO:0051960 248 0.028
forebrain development GO:0030900 2 0.028
autophagic cell death GO:0048102 83 0.027
cellular response to oxygen containing compound GO:1901701 79 0.026
negative regulation of apoptotic process GO:0043066 63 0.026
photoreceptor cell development GO:0042461 96 0.026
antimicrobial humoral response GO:0019730 99 0.026
regulation of cellular component size GO:0032535 98 0.025
compound eye development GO:0048749 307 0.025
defense response to gram negative bacterium GO:0050829 94 0.025
eye photoreceptor cell development GO:0042462 81 0.024
appendage morphogenesis GO:0035107 397 0.024
regulation of canonical wnt signaling pathway GO:0060828 15 0.024
spermatogenesis GO:0007283 200 0.024
purine nucleoside catabolic process GO:0006152 112 0.024
positive regulation of protein metabolic process GO:0051247 128 0.023
mitotic cell cycle phase transition GO:0044772 138 0.023
chromatin remodeling GO:0006338 72 0.023
macromolecule catabolic process GO:0009057 161 0.023
single organism behavior GO:0044708 391 0.023
negative regulation of cell communication GO:0010648 223 0.023
regulation of developmental growth GO:0048638 174 0.023
positive regulation of nucleobase containing compound metabolic process GO:0045935 332 0.022
circadian rhythm GO:0007623 105 0.022
digestive tract morphogenesis GO:0048546 127 0.022
nucleobase containing small molecule metabolic process GO:0055086 174 0.021
determination of adult lifespan GO:0008340 137 0.021
eye morphogenesis GO:0048592 260 0.020
ribonucleoside catabolic process GO:0042454 112 0.019
genitalia development GO:0048806 26 0.019
Worm
intracellular receptor signaling pathway GO:0030522 19 0.019
positive regulation of signaling GO:0023056 243 0.018
sensory organ morphogenesis GO:0090596 260 0.018
response to transforming growth factor beta GO:0071559 18 0.018
regulation of embryonic development GO:0045995 68 0.018
proteasomal protein catabolic process GO:0010498 59 0.018
aging GO:0007568 143 0.018
organelle fission GO:0048285 340 0.017
mitotic dna damage checkpoint GO:0044773 74 0.017
glial cell fate determination GO:0007403 3 0.017
purine ribonucleotide metabolic process GO:0009150 145 0.017
ncrna metabolic process GO:0034660 43 0.017
negative regulation of cellular metabolic process GO:0031324 382 0.017
cellular amino acid metabolic process GO:0006520 61 0.017
regulation of wnt signaling pathway GO:0030111 68 0.017
actin filament based process GO:0030029 220 0.017
defense response GO:0006952 300 0.017
eye development GO:0001654 323 0.016
ribonucleotide catabolic process GO:0009261 109 0.016
establishment of rna localization GO:0051236 47 0.016
positive regulation of neurogenesis GO:0050769 41 0.016
maintenance of location in cell GO:0051651 28 0.016
regulation of postsynaptic membrane potential GO:0060078 5 0.016
negative regulation of cell death GO:0060548 81 0.016
dna metabolic process GO:0006259 227 0.016
embryonic morphogenesis GO:0048598 206 0.015
mitotic cell cycle checkpoint GO:0007093 88 0.015
histone exchange GO:0043486 21 0.015
intracellular protein transport GO:0006886 104 0.015
interspecies interaction between organisms GO:0044419 16 0.015
negative regulation of neurogenesis GO:0050768 53 0.014
regulation of transport GO:0051049 181 0.014
meiotic chromosome segregation GO:0045132 59 0.014
single organism carbohydrate metabolic process GO:0044723 72 0.014
wing disc dorsal ventral pattern formation GO:0048190 47 0.014
nucleoside triphosphate catabolic process GO:0009143 108 0.014
imaginal disc derived wing margin morphogenesis GO:0008587 41 0.014
neuromuscular junction development GO:0007528 149 0.014
maintenance of protein location GO:0045185 28 0.014
posttranscriptional gene silencing GO:0016441 46 0.013
telencephalon development GO:0021537 2 0.013
histone h2a ubiquitination GO:0033522 2 0.013
positive regulation of glial cell proliferation GO:0060252 5 0.013
ribonucleoprotein complex assembly GO:0022618 23 0.013
modification dependent protein catabolic process GO:0019941 78 0.013
spinal cord dorsal ventral patterning GO:0021513 1 0.013
cell cycle checkpoint GO:0000075 95 0.013
carboxylic acid metabolic process GO:0019752 92 0.012
regulation of neuroblast proliferation GO:1902692 34 0.012
purine containing compound catabolic process GO:0072523 112 0.012
cellular protein catabolic process GO:0044257 83 0.012
regulation of microtubule based process GO:0032886 49 0.012
rhythmic process GO:0048511 106 0.012
mitochondrial membrane organization GO:0007006 3 0.012
adult locomotory behavior GO:0008344 76 0.012
regulation of nucleocytoplasmic transport GO:0046822 35 0.011
mesenchymal cell development GO:0014031 1 0.011
carbohydrate derivative metabolic process GO:1901135 217 0.011
skin development GO:0043588 65 0.011
cellular macromolecular complex assembly GO:0034622 153 0.011
positive regulation of nucleocytoplasmic transport GO:0046824 24 0.011
response to lipid GO:0033993 38 0.011
cell maturation GO:0048469 144 0.011
vesicle organization GO:0016050 44 0.011
neuron recognition GO:0008038 101 0.011
humoral immune response GO:0006959 117 0.011
establishment or maintenance of cell polarity GO:0007163 167 0.011
cellular macromolecule localization GO:0070727 220 0.011
regulation of cellular component biogenesis GO:0044087 201 0.011
regulation of cell development GO:0060284 215 0.011
nitrogen compound transport GO:0071705 85 0.011
regulation of circadian rhythm GO:0042752 49 0.011
carbohydrate metabolic process GO:0005975 82 0.011
positive regulation of nervous system development GO:0051962 69 0.010
negative regulation of neural precursor cell proliferation GO:2000178 27 0.010
nucleobase containing compound transport GO:0015931 56 0.010
negative regulation of cell development GO:0010721 62 0.010
cellular response to nutrient levels GO:0031669 62 0.010
negative regulation of signaling GO:0023057 219 0.010
developmental pigmentation GO:0048066 68 0.010
intracellular signal transduction GO:0035556 300 0.010
locomotory behavior GO:0007626 176 0.010
diterpenoid biosynthetic process GO:0016102 1 0.010

dom disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

Disease DO term ID Size Probability Func Analog Org
cancer DOID:162 0 0.061
disease of cellular proliferation DOID:14566 0 0.061
organ system cancer DOID:0050686 0 0.061
disease of anatomical entity DOID:7 0 0.011
nervous system disease DOID:863 0 0.011