Drosophila melanogaster

56 known processes

prod (Dmel_CG18608)

proliferation disrupter

(Aliases: l(2)88/10,PROD,Dmel\CG18608,l(2)k08810,CG18608,Prod)

prod biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
dna conformation change GO:0071103 105 0.813
imaginal disc growth GO:0007446 37 0.617
rhythmic behavior GO:0007622 76 0.501
circadian rhythm GO:0007623 105 0.424
regulation of catabolic process GO:0009894 170 0.417
cell proliferation GO:0008283 299 0.376
meiotic dna double strand break formation GO:0042138 1 0.357
circadian behavior GO:0048512 76 0.313
negative regulation of rna metabolic process GO:0051253 251 0.306
negative regulation of signal transduction GO:0009968 206 0.298
mitotic sister chromatid segregation GO:0000070 87 0.295
mitotic nuclear division GO:0007067 213 0.290
meiotic nuclear division GO:0007126 151 0.289
embryo development ending in birth or egg hatching GO:0009792 152 0.265
organ growth GO:0035265 56 0.242
cell division GO:0051301 248 0.238
negative regulation of cellular metabolic process GO:0031324 382 0.238
somatic stem cell division GO:0048103 37 0.236
regulation of cell proliferation GO:0042127 163 0.224
establishment or maintenance of cell polarity GO:0007163 167 0.209
asymmetric neuroblast division GO:0055059 33 0.208
negative regulation of cell communication GO:0010648 223 0.175
single organism behavior GO:0044708 391 0.174
regulation of notch signaling pathway GO:0008593 100 0.167
nuclear division GO:0000280 332 0.164
negative regulation of erk1 and erk2 cascade GO:0070373 3 0.163
organelle fission GO:0048285 340 0.143
cell fate determination GO:0001709 91 0.143
anatomical structure homeostasis GO:0060249 97 0.140
multi organism behavior GO:0051705 175 0.139
spindle organization GO:0007051 253 0.135
mitotic spindle organization GO:0007052 220 0.130
negative regulation of signaling GO:0023057 219 0.129
positive regulation of signal transduction GO:0009967 223 0.116
gene silencing GO:0016458 138 0.115
developmental growth GO:0048589 280 0.115
locomotory behavior GO:0007626 176 0.111
sister chromatid segregation GO:0000819 92 0.109
mitotic sister chromatid separation GO:0051306 30 0.106
negative regulation of meiotic cell cycle GO:0051447 2 0.104
regulation of gene silencing GO:0060968 63 0.104
asymmetric cell division GO:0008356 37 0.102
negative regulation of chromosome organization GO:2001251 19 0.102
columnar cuboidal epithelial cell differentiation GO:0002065 256 0.100
neuronal stem cell division GO:0036445 35 0.099
asymmetric stem cell division GO:0098722 49 0.096
negative regulation of transcription dna templated GO:0045892 237 0.091
immune system process GO:0002376 347 0.089
negative regulation of macromolecule biosynthetic process GO:0010558 270 0.089
positive regulation of nucleobase containing compound metabolic process GO:0045935 332 0.087
positive regulation of macromolecule metabolic process GO:0010604 405 0.085
positive regulation of nucleoside metabolic process GO:0045979 47 0.085
organonitrogen compound catabolic process GO:1901565 128 0.085
neuroblast proliferation GO:0007405 74 0.083
lymph gland development GO:0048542 28 0.082
regulation of metaphase anaphase transition of cell cycle GO:1902099 26 0.081
locomotor rhythm GO:0045475 56 0.077
oocyte development GO:0048599 124 0.077
positive regulation of cell communication GO:0010647 250 0.077
ribonucleoside catabolic process GO:0042454 112 0.076
negative regulation of developmental growth GO:0048640 64 0.075
negative regulation of cellular macromolecule biosynthetic process GO:2000113 267 0.074
chromosome organization GO:0051276 360 0.073
negative regulation of gene expression GO:0010629 387 0.072
regulation of cell division GO:0051302 72 0.070
stem cell division GO:0017145 69 0.069
regulation of chromatin silencing GO:0031935 36 0.069
larval development GO:0002164 104 0.068
negative regulation of response to stimulus GO:0048585 258 0.068
meiotic cell cycle GO:0051321 171 0.066
regulation of circadian rhythm GO:0042752 49 0.065
regulation of gene expression epigenetic GO:0040029 128 0.064
negative regulation of nitrogen compound metabolic process GO:0051172 265 0.064
regulation of developmental growth GO:0048638 174 0.064
digestive system development GO:0055123 149 0.061
negative regulation of phosphate metabolic process GO:0045936 45 0.061
dna replication initiation GO:0006270 6 0.061
positive regulation of hydrolase activity GO:0051345 78 0.060
ubiquitin dependent protein catabolic process GO:0006511 78 0.060
negative regulation of gene expression epigenetic GO:0045814 77 0.059
rhythmic process GO:0048511 106 0.058
positive regulation of signaling GO:0023056 243 0.058
macromolecular complex assembly GO:0065003 256 0.058
meiosis i GO:0007127 59 0.057
reproductive behavior GO:0019098 122 0.056
positive regulation of catabolic process GO:0009896 105 0.056
chromatin silencing GO:0006342 76 0.056
regulation of mitotic sister chromatid separation GO:0010965 28 0.054
negative regulation of intracellular signal transduction GO:1902532 57 0.053
negative regulation of mapk cascade GO:0043409 23 0.053
regulation of epithelial cell proliferation GO:0050678 4 0.053
reciprocal meiotic recombination GO:0007131 19 0.053
positive regulation of cellular biosynthetic process GO:0031328 316 0.053
regulation of protein catabolic process GO:0042176 55 0.052
muscle structure development GO:0061061 224 0.052
catabolic process GO:0009056 409 0.052
negative regulation of developmental process GO:0051093 201 0.052
regulation of meiosis GO:0040020 3 0.051
single organism cellular localization GO:1902580 180 0.051
negative regulation of phosphorylation GO:0042326 35 0.050
immune system development GO:0002520 57 0.050
neuroblast division GO:0055057 35 0.050
multi organism reproductive behavior GO:0044705 121 0.049
notch signaling pathway GO:0007219 120 0.048
ribonucleoside monophosphate catabolic process GO:0009158 39 0.048
negative regulation of phosphorus metabolic process GO:0010563 45 0.048
negative regulation of cell division GO:0051782 17 0.047
intracellular transport GO:0046907 228 0.047
meiotic chromosome condensation GO:0010032 3 0.047
malpighian tubule development GO:0072002 64 0.047
muscle organ development GO:0007517 127 0.046
regulation of proteasomal protein catabolic process GO:0061136 39 0.046
circadian regulation of gene expression GO:0032922 5 0.046
regulation of phosphate metabolic process GO:0019220 210 0.046
compound eye morphogenesis GO:0001745 249 0.045
wnt signaling pathway GO:0016055 98 0.045
homeostatic process GO:0042592 199 0.045
regulation of cell cycle GO:0051726 291 0.045
growth GO:0040007 359 0.045
purine ribonucleoside triphosphate catabolic process GO:0009207 108 0.045
imaginal disc pattern formation GO:0007447 91 0.045
negative regulation of organelle organization GO:0010639 56 0.044
positive regulation of nucleic acid templated transcription GO:1903508 266 0.043
multicellular organismal reproductive behavior GO:0033057 110 0.043
negative regulation of sister chromatid segregation GO:0033046 13 0.042
negative regulation of nucleobase containing compound metabolic process GO:0045934 261 0.042
negative regulation of growth GO:0045926 84 0.041
negative regulation of multicellular organismal process GO:0051241 142 0.041
endomembrane system organization GO:0010256 119 0.041
oocyte maturation GO:0001556 3 0.041
regulation of growth GO:0040008 233 0.041
organonitrogen compound metabolic process GO:1901564 318 0.041
renal tubule morphogenesis GO:0061333 44 0.040
negative regulation of synapse assembly GO:0051964 39 0.040
chromosome condensation GO:0030261 41 0.039
purine nucleoside triphosphate metabolic process GO:0009144 119 0.039
regulation of cellular amine metabolic process GO:0033238 3 0.038
stem cell differentiation GO:0048863 117 0.038
reciprocal dna recombination GO:0035825 19 0.038
neuron fate commitment GO:0048663 50 0.038
small molecule metabolic process GO:0044281 305 0.038
positive regulation of rna biosynthetic process GO:1902680 266 0.037
negative regulation of protein metabolic process GO:0051248 85 0.037
glycosyl compound metabolic process GO:1901657 127 0.037
regulation of mitotic metaphase anaphase transition GO:0030071 26 0.037
protein acetylation GO:0006473 39 0.036
protein localization to plasma membrane GO:0072659 13 0.036
purine nucleoside catabolic process GO:0006152 112 0.035
photoreceptor cell differentiation GO:0046530 170 0.035
negative regulation of rna biosynthetic process GO:1902679 240 0.035
regulation of organelle organization GO:0033043 196 0.035
female meiotic division GO:0007143 70 0.035
columnar cuboidal epithelial cell development GO:0002066 249 0.035
neuron projection guidance GO:0097485 241 0.035
programmed cell death GO:0012501 257 0.034
positive regulation of wnt signaling pathway GO:0030177 25 0.034
brain development GO:0007420 120 0.034
histone h4 acetylation GO:0043967 13 0.034
negative regulation of mitotic sister chromatid separation GO:2000816 13 0.034
glycosyl compound catabolic process GO:1901658 112 0.034
protein dna complex subunit organization GO:0071824 86 0.033
body morphogenesis GO:0010171 2 0.033
regulation of protein metabolic process GO:0051246 256 0.033
positive regulation of nitrogen compound metabolic process GO:0051173 354 0.033
negative regulation of cellular component organization GO:0051129 108 0.032
negative regulation of molecular function GO:0044092 51 0.032
negative regulation of cell differentiation GO:0045596 143 0.032
protein catabolic process GO:0030163 101 0.032
negative regulation of nervous system development GO:0051961 92 0.032
molting cycle GO:0042303 56 0.032
digestive tract morphogenesis GO:0048546 127 0.031
cardiovascular system development GO:0072358 82 0.031
single organism catabolic process GO:0044712 228 0.031
central nervous system development GO:0007417 201 0.031
oocyte differentiation GO:0009994 145 0.031
hematopoietic or lymphoid organ development GO:0048534 57 0.031
negative regulation of biosynthetic process GO:0009890 277 0.030
positive regulation of response to stimulus GO:0048584 323 0.030
metaphase anaphase transition of cell cycle GO:0044784 28 0.030
stem cell proliferation GO:0072089 88 0.030
circulatory system development GO:0072359 82 0.030
cell maturation GO:0048469 144 0.029
positive regulation of molecular function GO:0044093 136 0.029
wing disc morphogenesis GO:0007472 344 0.029
positive regulation of transcription dna templated GO:0045893 266 0.028
cell motility GO:0048870 251 0.028
nucleotide catabolic process GO:0009166 109 0.028
positive regulation of gene expression GO:0010628 290 0.028
regulation of mrna processing GO:0050684 71 0.028
meiotic cell cycle process GO:1903046 132 0.027
regulation of mapk cascade GO:0043408 92 0.027
carbohydrate derivative metabolic process GO:1901135 217 0.027
peptidyl threonine phosphorylation GO:0018107 2 0.027
nucleoside triphosphate catabolic process GO:0009143 108 0.027
regulation of pathway restricted smad protein phosphorylation GO:0060393 1 0.027
tube morphogenesis GO:0035239 191 0.026
purine nucleoside metabolic process GO:0042278 127 0.026
regulation of cellular protein metabolic process GO:0032268 243 0.026
anaphase promoting complex dependent proteasomal ubiquitin dependent protein catabolic process GO:0031145 30 0.026
urogenital system development GO:0001655 72 0.026
heart process GO:0003015 37 0.026
regulation of proteolysis involved in cellular protein catabolic process GO:1903050 44 0.026
gland development GO:0048732 191 0.025
negative regulation of cellular protein metabolic process GO:0032269 85 0.025
tube development GO:0035295 244 0.025
cellular catabolic process GO:0044248 372 0.025
negative regulation of epithelial cell proliferation GO:0050680 4 0.025
dna packaging GO:0006323 91 0.025
eye photoreceptor cell differentiation GO:0001754 145 0.025
microtubule cytoskeleton organization involved in mitosis GO:1902850 52 0.024
regulation of erk1 and erk2 cascade GO:0070372 39 0.024
cellular component assembly involved in morphogenesis GO:0010927 151 0.023
purine ribonucleoside catabolic process GO:0046130 112 0.023
organelle assembly GO:0070925 198 0.023
lateral inhibition GO:0046331 206 0.023
cellular protein localization GO:0034613 160 0.023
cell cell signaling involved in cell fate commitment GO:0045168 210 0.023
purine containing compound metabolic process GO:0072521 155 0.022
stem cell maintenance GO:0019827 67 0.022
regulation of molecular function GO:0065009 217 0.022
dorsal ventral pattern formation GO:0009953 133 0.022
protein localization GO:0008104 284 0.022
nucleoside phosphate metabolic process GO:0006753 162 0.021
cell migration GO:0016477 238 0.021
oocyte construction GO:0007308 112 0.021
negative regulation of mitotic cell cycle GO:0045930 109 0.021
establishment of spindle orientation GO:0051294 18 0.021
regulation of wnt signaling pathway GO:0030111 68 0.021
sensory organ morphogenesis GO:0090596 260 0.021
nucleobase containing compound catabolic process GO:0034655 165 0.021
chromosome segregation GO:0007059 157 0.021
organic substance catabolic process GO:1901575 308 0.021
enteroendocrine cell differentiation GO:0035883 1 0.021
negative regulation of nucleic acid templated transcription GO:1903507 240 0.021
compound eye photoreceptor cell differentiation GO:0001751 140 0.020
negative regulation of notch signaling pathway GO:0045746 41 0.020
head development GO:0060322 135 0.020
regionalization GO:0003002 416 0.020
establishment of localization in cell GO:0051649 402 0.020
epithelial cell development GO:0002064 274 0.020
purine ribonucleoside metabolic process GO:0046128 127 0.020
nucleoside catabolic process GO:0009164 112 0.020
histone h2a acetylation GO:0043968 1 0.020
regulation of multicellular organismal development GO:2000026 414 0.019
ras protein signal transduction GO:0007265 88 0.019
mrna splice site selection GO:0006376 1 0.019
negative regulation of cellular biosynthetic process GO:0031327 277 0.019
protein complex assembly GO:0006461 200 0.019
circadian sleep wake cycle sleep GO:0050802 23 0.019
internal protein amino acid acetylation GO:0006475 38 0.019
dna replication checkpoint GO:0000076 8 0.018
regulation of cellular localization GO:0060341 136 0.018
taxis GO:0042330 304 0.018
lipid storage GO:0019915 38 0.018
localization of cell GO:0051674 257 0.018
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 54 0.018
regulation of protein deacetylation GO:0090311 2 0.018
purine nucleoside triphosphate catabolic process GO:0009146 108 0.018
regulation of meiotic cell cycle GO:0051445 9 0.018
purine ribonucleotide metabolic process GO:0009150 145 0.018
protein complex biogenesis GO:0070271 201 0.018
amine metabolic process GO:0009308 12 0.018
retina development in camera type eye GO:0060041 4 0.018
meiotic dna double strand break formation involved in reciprocal meiotic recombination GO:0010780 1 0.018
chemotaxis GO:0006935 249 0.018
regulation of phosphorylation GO:0042325 147 0.018
ribonucleotide metabolic process GO:0009259 145 0.018
nitrogen compound transport GO:0071705 85 0.018
transcription from rna polymerase ii promoter GO:0006366 368 0.017
negative regulation of cell cycle GO:0045786 116 0.017
oocyte axis specification GO:0007309 108 0.017
imaginal disc derived appendage development GO:0048737 399 0.017
dendrite development GO:0016358 204 0.017
hindgut morphogenesis GO:0007442 58 0.017
vesicle mediated transport GO:0016192 381 0.017
endocytosis GO:0006897 310 0.017
ribonucleoside metabolic process GO:0009119 127 0.017
regulation of heterochromatin assembly GO:0031445 8 0.017
neural precursor cell proliferation GO:0061351 75 0.017
regulation of cellular protein catabolic process GO:1903362 44 0.017
proteasomal protein catabolic process GO:0010498 59 0.016
purine ribonucleoside triphosphate metabolic process GO:0009205 119 0.016
regulation of hemocyte proliferation GO:0035206 37 0.016
renal system development GO:0072001 72 0.016
cellular macromolecular complex assembly GO:0034622 153 0.016
ribose phosphate metabolic process GO:0019693 145 0.016
r7 cell differentiation GO:0045466 43 0.016
dna templated transcription elongation GO:0006354 18 0.016
cytoplasmic transport GO:0016482 130 0.016
cellular response to carbon dioxide GO:0071244 2 0.016
regulation of mitotic sister chromatid segregation GO:0033047 28 0.016
epithelial cell differentiation GO:0030855 322 0.016
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 116 0.016
positive regulation of developmental growth GO:0048639 62 0.015
regulation of nuclear division GO:0051783 58 0.015
dephosphorylation GO:0016311 51 0.015
hindgut development GO:0061525 58 0.015
negative regulation of cell proliferation GO:0008285 69 0.015
negative regulation of programmed cell death GO:0043069 72 0.015
protein acylation GO:0043543 42 0.015
ribonucleoside triphosphate catabolic process GO:0009203 108 0.015
aromatic compound catabolic process GO:0019439 166 0.015
multi multicellular organism process GO:0044706 123 0.015
nucleoside metabolic process GO:0009116 127 0.015
positive regulation of chromatin silencing GO:0031937 16 0.015
embryonic hindgut morphogenesis GO:0048619 48 0.015
positive regulation of growth GO:0045927 75 0.015
developmental maturation GO:0021700 172 0.015
neuromuscular synaptic transmission GO:0007274 67 0.015
positive regulation of biosynthetic process GO:0009891 316 0.014
regulation of mitosis GO:0007088 56 0.014
mapk cascade GO:0000165 107 0.014
response to oxygen containing compound GO:1901700 200 0.014
positive regulation of developmental process GO:0051094 143 0.014
purine containing compound catabolic process GO:0072523 112 0.014
peptidyl lysine acetylation GO:0018394 39 0.014
regulation of purine nucleotide catabolic process GO:0033121 48 0.014
appendage morphogenesis GO:0035107 397 0.014
positive regulation of heterochromatin assembly GO:0031453 5 0.014
morphogenesis of an epithelium GO:0002009 276 0.014
regulation of cellular catabolic process GO:0031329 157 0.013
eye morphogenesis GO:0048592 260 0.013
dna metabolic process GO:0006259 227 0.013
nucleosome mobilization GO:0042766 9 0.013
metaphase anaphase transition of mitotic cell cycle GO:0007091 28 0.013
germarium derived female germ line cyst encapsulation GO:0030708 8 0.013
proteolysis involved in cellular protein catabolic process GO:0051603 83 0.013
establishment of spindle localization GO:0051293 22 0.012
small gtpase mediated signal transduction GO:0007264 88 0.012
dna geometric change GO:0032392 16 0.012
regulation of sister chromatid segregation GO:0033045 28 0.012
negative regulation of cell development GO:0010721 62 0.012
regulation of histone deacetylation GO:0031063 2 0.012
negative regulation of mitotic metaphase anaphase transition GO:0045841 13 0.012
mitotic spindle checkpoint GO:0071174 11 0.012
atp catabolic process GO:0006200 38 0.012
erk1 and erk2 cascade GO:0070371 39 0.012
negative regulation of mitosis GO:0045839 16 0.012
regulation of r7 cell differentiation GO:0045676 15 0.011
dna recombination GO:0006310 32 0.011
ribonucleoside triphosphate metabolic process GO:0009199 119 0.011
heterocycle catabolic process GO:0046700 166 0.011
cellular response to peptide hormone stimulus GO:0071375 28 0.011
mrna processing GO:0006397 104 0.011
regulation of mitotic cell cycle phase transition GO:1901990 130 0.011
mesoderm development GO:0007498 78 0.011
sex differentiation GO:0007548 81 0.011
eggshell chorion assembly GO:0007306 66 0.011
proteolysis GO:0006508 192 0.011
regulation of rna splicing GO:0043484 69 0.011
dna dependent dna replication GO:0006261 17 0.011
microtubule polymerization or depolymerization GO:0031109 39 0.011
negative regulation of proteasomal protein catabolic process GO:1901799 16 0.011
ribonucleotide catabolic process GO:0009261 109 0.011
single organism intracellular transport GO:1902582 207 0.011
epithelial tube morphogenesis GO:0060562 88 0.011
regulation of proteasomal ubiquitin dependent protein catabolic process GO:0032434 37 0.011
positive regulation of rna metabolic process GO:0051254 271 0.011
protein heterooligomerization GO:0051291 4 0.010
negative regulation of transcription from rna polymerase ii promoter GO:0000122 119 0.010
neurological system process GO:0050877 358 0.010
eye photoreceptor cell fate commitment GO:0042706 37 0.010
regulation of intracellular signal transduction GO:1902531 236 0.010
cellular amine metabolic process GO:0044106 12 0.010
regulation of protein modification process GO:0031399 112 0.010

prod disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

Disease DO term ID Size Probability Func Analog Org