Drosophila melanogaster

50 known processes

MED18 (Dmel_CG14802)

Mediator complex subunit 18

(Aliases: EG:63B12.13,Dmel\CG14802,CG14802,p28/CG14802,Med18,dp28b,p28,Srb5/Med28b)

MED18 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
regulation of multicellular organismal development GO:2000026 414 0.110
positive regulation of cellular biosynthetic process GO:0031328 316 0.095
positive regulation of gene expression GO:0010628 290 0.080
regulation of cell proliferation GO:0042127 163 0.078
cellular nitrogen compound catabolic process GO:0044270 165 0.077
regulation of cellular component biogenesis GO:0044087 201 0.063
negative regulation of cell cycle phase transition GO:1901988 103 0.062
transcription from rna polymerase ii promoter GO:0006366 368 0.059
negative regulation of developmental process GO:0051093 201 0.059
positive regulation of nitrogen compound metabolic process GO:0051173 354 0.057
aromatic compound catabolic process GO:0019439 166 0.054
positive regulation of nucleobase containing compound metabolic process GO:0045935 332 0.052
positive regulation of nucleic acid templated transcription GO:1903508 266 0.049
nucleobase containing small molecule metabolic process GO:0055086 174 0.047
protein localization GO:0008104 284 0.046
positive regulation of macromolecule metabolic process GO:0010604 405 0.046
protein modification by small protein conjugation or removal GO:0070647 106 0.045
morphogenesis of an epithelium GO:0002009 276 0.044
endomembrane system organization GO:0010256 119 0.041
mrna metabolic process GO:0016071 124 0.041
positive regulation of biosynthetic process GO:0009891 316 0.041
phagocytosis GO:0006909 215 0.040
chromatin modification GO:0016568 147 0.040
purine ribonucleotide metabolic process GO:0009150 145 0.039
nucleobase containing compound catabolic process GO:0034655 165 0.039
enzyme linked receptor protein signaling pathway GO:0007167 179 0.039
meiotic nuclear division GO:0007126 151 0.039
regionalization GO:0003002 416 0.039
nuclear division GO:0000280 332 0.038
protein localization to organelle GO:0033365 82 0.037
heterocycle catabolic process GO:0046700 166 0.036
protein targeting GO:0006605 64 0.035
ribonucleoside triphosphate metabolic process GO:0009199 119 0.035
cell proliferation GO:0008283 299 0.034
negative regulation of cellular metabolic process GO:0031324 382 0.034
larval development GO:0002164 104 0.033
nucleoside phosphate metabolic process GO:0006753 162 0.033
ribonucleotide metabolic process GO:0009259 145 0.032
regulation of growth GO:0040008 233 0.031
translation GO:0006412 69 0.030
vesicle mediated transport GO:0016192 381 0.030
positive regulation of rna metabolic process GO:0051254 271 0.030
cellular protein localization GO:0034613 160 0.029
organophosphate metabolic process GO:0019637 195 0.029
negative regulation of mitotic cell cycle GO:0045930 109 0.029
cellular protein modification process GO:0006464 438 0.029
regulation of mitotic cell cycle GO:0007346 190 0.029
protein modification process GO:0036211 438 0.029
carbohydrate derivative metabolic process GO:1901135 217 0.029
positive regulation of cellular amino acid metabolic process GO:0045764 0 0.028
negative regulation of nervous system development GO:0051961 92 0.028
regulation of intracellular signal transduction GO:1902531 236 0.028
developmental growth GO:0048589 280 0.027
organonitrogen compound metabolic process GO:1901564 318 0.027
organic cyclic compound catabolic process GO:1901361 168 0.027
regulation of mitotic cell cycle phase transition GO:1901990 130 0.026
cellular macromolecule localization GO:0070727 220 0.026
establishment of organelle localization GO:0051656 122 0.026
establishment of localization in cell GO:0051649 402 0.026
nucleotide metabolic process GO:0009117 161 0.026
cell cycle checkpoint GO:0000075 95 0.026
mitotic nuclear division GO:0007067 213 0.025
single organism intracellular transport GO:1902582 207 0.025
macromolecular complex assembly GO:0065003 256 0.025
growth GO:0040007 359 0.025
regulation of cell differentiation GO:0045595 302 0.025
endocytosis GO:0006897 310 0.025
negative regulation of macromolecule biosynthetic process GO:0010558 270 0.024
positive regulation of macromolecule biosynthetic process GO:0010557 283 0.024
cytoplasmic mrna processing body assembly GO:0033962 10 0.024
positive regulation of transcription dna templated GO:0045893 266 0.024
regulation of cell cycle process GO:0010564 181 0.023
purine containing compound metabolic process GO:0072521 155 0.023
organic substance catabolic process GO:1901575 308 0.022
single organism membrane organization GO:0044802 93 0.022
cellular catabolic process GO:0044248 372 0.022
organophosphate catabolic process GO:0046434 112 0.022
purine containing compound catabolic process GO:0072523 112 0.022
small molecule metabolic process GO:0044281 305 0.021
organic substance transport GO:0071702 257 0.021
embryonic pattern specification GO:0009880 174 0.021
macromolecular complex disassembly GO:0032984 37 0.021
regulation of cell cycle phase transition GO:1901987 130 0.020
organelle fission GO:0048285 340 0.020
single organism cellular localization GO:1902580 180 0.020
regulation of cell development GO:0060284 215 0.020
protein modification by small protein removal GO:0070646 28 0.020
cellular response to dna damage stimulus GO:0006974 223 0.019
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 116 0.019
mitotic dna damage checkpoint GO:0044773 74 0.019
ribose phosphate metabolic process GO:0019693 145 0.019
intracellular signal transduction GO:0035556 300 0.019
cellular component disassembly GO:0022411 46 0.019
cell cell signaling involved in cell fate commitment GO:0045168 210 0.018
response to organic substance GO:0010033 284 0.018
positive regulation of transcription from rna polymerase ii promoter GO:0045944 204 0.018
purine nucleotide metabolic process GO:0006163 146 0.018
negative regulation of cellular macromolecule biosynthetic process GO:2000113 267 0.018
response to oxygen containing compound GO:1901700 200 0.018
macromolecule catabolic process GO:0009057 161 0.017
protein localization to nucleus GO:0034504 55 0.017
positive regulation of rna biosynthetic process GO:1902680 266 0.017
nucleoside triphosphate metabolic process GO:0009141 120 0.017
negative regulation of multicellular organismal process GO:0051241 142 0.017
regulation of nervous system development GO:0051960 248 0.016
intracellular transport GO:0046907 228 0.016
posttranscriptional regulation of gene expression GO:0010608 145 0.016
death GO:0016265 284 0.016
eye photoreceptor cell differentiation GO:0001754 145 0.016
regulation of meiosis GO:0040020 3 0.016
nucleotide catabolic process GO:0009166 109 0.015
regulation of cellular catabolic process GO:0031329 157 0.015
regulation of transcription from rna polymerase ii promoter GO:0006357 378 0.015
rna localization GO:0006403 115 0.015
establishment of protein localization GO:0045184 163 0.015
negative regulation of nucleic acid templated transcription GO:1903507 240 0.015
protein transport GO:0015031 155 0.015
nuclear transcribed mrna catabolic process GO:0000956 24 0.015
dna integrity checkpoint GO:0031570 81 0.014
negative regulation of neuroblast proliferation GO:0007406 27 0.014
purine ribonucleoside catabolic process GO:0046130 112 0.014
defense response to other organism GO:0098542 225 0.014
intracellular protein transport GO:0006886 104 0.014
ribonucleotide catabolic process GO:0009261 109 0.014
cellular response to chemical stimulus GO:0070887 199 0.014
molting cycle GO:0042303 56 0.013
nucleoside phosphate catabolic process GO:1901292 110 0.013
purine ribonucleoside metabolic process GO:0046128 127 0.013
negative regulation of response to stimulus GO:0048585 258 0.013
cellular protein complex assembly GO:0043623 71 0.013
negative regulation of cell differentiation GO:0045596 143 0.013
cell death GO:0008219 279 0.013
anterior posterior pattern specification GO:0009952 136 0.013
cellular macromolecular complex assembly GO:0034622 153 0.013
mitotic g2 m transition checkpoint GO:0044818 70 0.013
purine nucleotide catabolic process GO:0006195 109 0.013
positive regulation of signal transduction GO:0009967 223 0.013
negative regulation of cellular biosynthetic process GO:0031327 277 0.013
regulation of microtubule polymerization or depolymerization GO:0031110 27 0.013
regulation of multi organism process GO:0043900 131 0.013
carbohydrate derivative catabolic process GO:1901136 118 0.013
regulation of cell cycle GO:0051726 291 0.013
dna templated transcription initiation GO:0006352 25 0.013
nucleocytoplasmic transport GO:0006913 72 0.013
negative regulation of cell proliferation GO:0008285 69 0.013
rna interference GO:0016246 27 0.012
embryonic axis specification GO:0000578 107 0.012
ribonucleoprotein complex disassembly GO:0032988 1 0.012
positive regulation of response to stimulus GO:0048584 323 0.012
regulation of organelle organization GO:0033043 196 0.012
positive regulation of protein modification process GO:0031401 58 0.012
ras protein signal transduction GO:0007265 88 0.012
nucleoside metabolic process GO:0009116 127 0.012
negative regulation of cell cycle process GO:0010948 109 0.012
negative regulation of signal transduction GO:0009968 206 0.012
cell cycle phase transition GO:0044770 140 0.012
purine nucleoside metabolic process GO:0042278 127 0.012
generation of precursor metabolites and energy GO:0006091 42 0.012
organelle localization GO:0051640 148 0.011
regulation of protein modification process GO:0031399 112 0.011
negative regulation of cell cycle GO:0045786 116 0.011
purine nucleoside catabolic process GO:0006152 112 0.011
regulation of gene expression epigenetic GO:0040029 128 0.011
regulation of molecular function GO:0065009 217 0.011
regulation of catabolic process GO:0009894 170 0.011
positive regulation of developmental process GO:0051094 143 0.011
rna transport GO:0050658 46 0.011
glycosyl compound metabolic process GO:1901657 127 0.011
nucleoside catabolic process GO:0009164 112 0.011
embryo development ending in birth or egg hatching GO:0009792 152 0.011
epidermal growth factor receptor signaling pathway GO:0007173 58 0.011
chromosome segregation GO:0007059 157 0.011
gtp catabolic process GO:0006184 72 0.010
regulation of catalytic activity GO:0050790 185 0.010
regulation of apoptotic process GO:0042981 130 0.010
cellular macromolecule catabolic process GO:0044265 136 0.010

MED18 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.021