Drosophila melanogaster

15 known processes

Ubc-E2H (Dmel_CG2257)

CG2257 gene product from transcript CG2257-RA

(Aliases: CG2257,Dmel\CG2257,dUbc-E2H,UbcE2H)

Ubc-E2H biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
negative regulation of cell communication GO:0010648 223 0.317
protein modification process GO:0036211 438 0.299
Human Yeast Mouse
cellular response to dna damage stimulus GO:0006974 223 0.174
regulation of cell differentiation GO:0045595 302 0.161
regulation of growth GO:0040008 233 0.156
macromolecular complex assembly GO:0065003 256 0.133
membrane organization GO:0061024 112 0.127
nucleobase containing compound catabolic process GO:0034655 165 0.122
organophosphate metabolic process GO:0019637 195 0.121
establishment of localization in cell GO:0051649 402 0.118
growth GO:0040007 359 0.117
intracellular transport GO:0046907 228 0.115
cell cell signaling involved in cell fate commitment GO:0045168 210 0.114
protein complex biogenesis GO:0070271 201 0.114
regulation of cellular localization GO:0060341 136 0.112
single organism membrane organization GO:0044802 93 0.109
organic substance transport GO:0071702 257 0.108
establishment or maintenance of cell polarity GO:0007163 167 0.108
carbohydrate derivative catabolic process GO:1901136 118 0.095
catabolic process GO:0009056 409 0.095
Yeast Mouse
regulation of localization GO:0032879 275 0.094
immune system process GO:0002376 347 0.093
response to organic substance GO:0010033 284 0.090
spermatid development GO:0007286 98 0.085
response to lipopolysaccharide GO:0032496 4 0.081
heterocycle catabolic process GO:0046700 166 0.077
organonitrogen compound metabolic process GO:1901564 318 0.076
vesicle mediated transport GO:0016192 381 0.075
muscle structure development GO:0061061 224 0.072
purine nucleoside metabolic process GO:0042278 127 0.072
male gamete generation GO:0048232 201 0.069
ribonucleoside metabolic process GO:0009119 127 0.069
purine nucleoside triphosphate metabolic process GO:0009144 119 0.068
organic substance catabolic process GO:1901575 308 0.064
Yeast Mouse
tube development GO:0035295 244 0.063
gland development GO:0048732 191 0.063
imaginal disc derived appendage development GO:0048737 399 0.060
nucleobase containing small molecule metabolic process GO:0055086 174 0.060
negative regulation of cellular metabolic process GO:0031324 382 0.059
Yeast
nucleoside metabolic process GO:0009116 127 0.058
protein complex assembly GO:0006461 200 0.058
negative regulation of signaling GO:0023057 219 0.058
aromatic compound catabolic process GO:0019439 166 0.058
endocytosis GO:0006897 310 0.057
immune response GO:0006955 246 0.056
peptidyl amino acid modification GO:0018193 105 0.054
purine nucleotide metabolic process GO:0006163 146 0.051
regulation of multicellular organismal development GO:2000026 414 0.050
regulation of anatomical structure size GO:0090066 163 0.049
regulation of cell cycle GO:0051726 291 0.049
single organism cellular localization GO:1902580 180 0.049
tissue death GO:0016271 102 0.049
lateral inhibition GO:0046331 206 0.048
small molecule metabolic process GO:0044281 305 0.048
Yeast
cell division GO:0051301 248 0.047
organic cyclic compound catabolic process GO:1901361 168 0.046
cellular catabolic process GO:0044248 372 0.046
Yeast Mouse
tube morphogenesis GO:0035239 191 0.045
response to oxygen containing compound GO:1901700 200 0.045
purine ribonucleoside metabolic process GO:0046128 127 0.044
cellular nitrogen compound catabolic process GO:0044270 165 0.044
cell motility GO:0048870 251 0.044
single organism catabolic process GO:0044712 228 0.043
nucleotide metabolic process GO:0009117 161 0.043
ribonucleoside catabolic process GO:0042454 112 0.043
purine containing compound catabolic process GO:0072523 112 0.043
negative regulation of signal transduction GO:0009968 206 0.042
regulation of production of molecular mediator of immune response GO:0002700 44 0.042
cellular response to organic substance GO:0071310 132 0.042
organelle fusion GO:0048284 46 0.042
ribonucleotide metabolic process GO:0009259 145 0.042
protein heterooligomerization GO:0051291 4 0.041
organelle assembly GO:0070925 198 0.040
spermatid differentiation GO:0048515 114 0.040
acetylcholine metabolic process GO:0008291 2 0.039
regulation of cellular catabolic process GO:0031329 157 0.038
regulation of organelle organization GO:0033043 196 0.038
salivary gland development GO:0007431 162 0.038
transcription from rna polymerase ii promoter GO:0006366 368 0.038
negative regulation of response to stimulus GO:0048585 258 0.037
response to external biotic stimulus GO:0043207 293 0.037
purine containing compound metabolic process GO:0072521 155 0.035
spermatogenesis GO:0007283 200 0.035
ribose phosphate metabolic process GO:0019693 145 0.034
response to other organism GO:0051707 293 0.034
purine nucleoside catabolic process GO:0006152 112 0.034
cellular macromolecule localization GO:0070727 220 0.033
cellular protein localization GO:0034613 160 0.032
regulation of immune effector process GO:0002697 52 0.032
guanosine containing compound catabolic process GO:1901069 74 0.030
appendage morphogenesis GO:0035107 397 0.030
carboxylic acid metabolic process GO:0019752 92 0.030
gland morphogenesis GO:0022612 145 0.030
cytoplasmic transport GO:0016482 130 0.030
regulation of transport GO:0051049 181 0.030
imaginal disc derived appendage morphogenesis GO:0035114 395 0.029
muscle cell differentiation GO:0042692 103 0.029
protein transport GO:0015031 155 0.029
cellular amine metabolic process GO:0044106 12 0.028
cellular protein complex assembly GO:0043623 71 0.028
purine ribonucleoside triphosphate catabolic process GO:0009207 108 0.028
cell death GO:0008219 279 0.028
regulation of cellular protein metabolic process GO:0032268 243 0.027
regulation of transcription from rna polymerase ii promoter GO:0006357 378 0.027
histolysis GO:0007559 102 0.027
purine ribonucleoside triphosphate metabolic process GO:0009205 119 0.027
actin cytoskeleton organization GO:0030036 206 0.027
purine ribonucleotide catabolic process GO:0009154 109 0.027
establishment of protein localization GO:0045184 163 0.026
regulation of molecular function GO:0065009 217 0.026
exocrine system development GO:0035272 162 0.026
secretion GO:0046903 109 0.026
nucleoside phosphate metabolic process GO:0006753 162 0.026
body morphogenesis GO:0010171 2 0.026
response to bacterium GO:0009617 198 0.025
post embryonic appendage morphogenesis GO:0035120 385 0.025
salivary gland morphogenesis GO:0007435 145 0.025
regulation of embryonic cell shape GO:0016476 30 0.025
meiotic cell cycle GO:0051321 171 0.025
protein localization GO:0008104 284 0.025
regulation of cell size GO:0008361 63 0.025
purine ribonucleoside catabolic process GO:0046130 112 0.024
cellular response to extracellular stimulus GO:0031668 64 0.024
purine ribonucleotide metabolic process GO:0009150 145 0.023
regulation of response to stress GO:0080134 200 0.023
ribonucleoside triphosphate metabolic process GO:0009199 119 0.023
regulation of protein metabolic process GO:0051246 256 0.023
appendage development GO:0048736 401 0.023
glycosyl compound metabolic process GO:1901657 127 0.023
protein catabolic process GO:0030163 101 0.023
Yeast Mouse
negative regulation of cell cycle phase transition GO:1901988 103 0.023
defense response GO:0006952 300 0.023
cellular component assembly involved in morphogenesis GO:0010927 151 0.022
phagocytosis GO:0006909 215 0.022
salivary gland histolysis GO:0035070 88 0.022
positive regulation of nucleobase containing compound metabolic process GO:0045935 332 0.021
cellular response to chemical stimulus GO:0070887 199 0.021
regulation of compound eye retinal cell programmed cell death GO:0046669 18 0.021
organic acid metabolic process GO:0006082 103 0.021
purine nucleotide catabolic process GO:0006195 109 0.021
regulation of defense response GO:0031347 102 0.021
ribonucleoside triphosphate catabolic process GO:0009203 108 0.020
positive regulation of cellular component organization GO:0051130 156 0.020
single organism intracellular transport GO:1902582 207 0.020
regulation of hydrolase activity GO:0051336 97 0.020
aging GO:0007568 143 0.020
response to wounding GO:0009611 94 0.020
cell proliferation GO:0008283 299 0.020
developmental programmed cell death GO:0010623 138 0.020
nucleoside triphosphate metabolic process GO:0009141 120 0.019
mitotic cell cycle checkpoint GO:0007093 88 0.019
regulation of secretion by cell GO:1903530 39 0.019
proteolysis GO:0006508 192 0.019
Yeast Mouse
multicellular organism growth GO:0035264 46 0.019
positive regulation of catabolic process GO:0009896 105 0.018
organophosphate catabolic process GO:0046434 112 0.018
negative regulation of mitotic cell cycle phase transition GO:1901991 103 0.018
multi organism behavior GO:0051705 175 0.018
glycosyl compound catabolic process GO:1901658 112 0.018
dna damage checkpoint GO:0000077 78 0.018
apoptotic process GO:0006915 159 0.018
cell migration GO:0016477 238 0.018
wing disc morphogenesis GO:0007472 344 0.017
salivary gland cell autophagic cell death GO:0035071 83 0.017
oxoacid metabolic process GO:0043436 103 0.017
lipid metabolic process GO:0006629 121 0.017
autophagic cell death GO:0048102 83 0.017
regulation of cellular component biogenesis GO:0044087 201 0.017
regulation of developmental growth GO:0048638 174 0.017
positive regulation of nitrogen compound metabolic process GO:0051173 354 0.017
positive regulation of developmental process GO:0051094 143 0.017
dna integrity checkpoint GO:0031570 81 0.017
macromolecule catabolic process GO:0009057 161 0.017
Yeast Mouse
regulation of macroautophagy GO:0016241 15 0.017
lipid localization GO:0010876 54 0.016
nucleotide catabolic process GO:0009166 109 0.016
ribonucleotide catabolic process GO:0009261 109 0.016
asymmetric stem cell division GO:0098722 49 0.016
response to biotic stimulus GO:0009607 294 0.016
imaginal disc derived wing morphogenesis GO:0007476 337 0.015
actin filament based process GO:0030029 220 0.015
striated muscle cell differentiation GO:0051146 90 0.015
positive regulation of immune effector process GO:0002699 28 0.015
wnt signaling pathway GO:0016055 98 0.015
negative regulation of cellular biosynthetic process GO:0031327 277 0.015
Yeast
organelle fission GO:0048285 340 0.015
negative regulation of growth GO:0045926 84 0.015
synaptic transmission GO:0007268 288 0.015
regulation of cell shape GO:0008360 113 0.015
regulation of tube size GO:0035150 46 0.015
male meiosis GO:0007140 52 0.015
regulation of catabolic process GO:0009894 170 0.015
neuron remodeling GO:0016322 29 0.014
regulation of cellular component size GO:0032535 98 0.014
positive regulation of transport GO:0051050 92 0.014
regulation of golgi to plasma membrane protein transport GO:0042996 6 0.014
positive regulation of production of molecular mediator of immune response GO:0002702 28 0.014
amine metabolic process GO:0009308 12 0.014
hemopoiesis GO:0030097 46 0.014
negative regulation of nitrogen compound metabolic process GO:0051172 265 0.014
stress activated protein kinase signaling cascade GO:0031098 55 0.014
programmed cell death GO:0012501 257 0.014
autophagy GO:0006914 108 0.014
positive regulation of immune system process GO:0002684 68 0.014
antimicrobial peptide biosynthetic process GO:0002777 38 0.013
regulation of protein localization GO:0032880 76 0.013
regulation of catalytic activity GO:0050790 185 0.013
phosphorylation GO:0016310 294 0.013
regulation of cell morphogenesis GO:0022604 163 0.013
neuroblast proliferation GO:0007405 74 0.013
immune effector process GO:0002252 98 0.013
innate immune response activating signal transduction GO:0002758 2 0.013
secretion by cell GO:0032940 101 0.013
larval development GO:0002164 104 0.013
cellular amide metabolic process GO:0043603 80 0.013
positive regulation of defense response GO:0031349 59 0.013
humoral immune response GO:0006959 117 0.013
lipid modification GO:0030258 24 0.013
response to organonitrogen compound GO:0010243 75 0.013
positive regulation of cellular biosynthetic process GO:0031328 316 0.013
regulation of apoptotic process GO:0042981 130 0.013
guanosine containing compound metabolic process GO:1901068 74 0.013
urogenital system development GO:0001655 72 0.012
epithelial tube morphogenesis GO:0060562 88 0.012
nucleoside triphosphate catabolic process GO:0009143 108 0.012
organonitrogen compound catabolic process GO:1901565 128 0.012
response to starvation GO:0042594 97 0.012
jnk cascade GO:0007254 50 0.012
response to nutrient levels GO:0031667 114 0.012
compound eye development GO:0048749 307 0.012
regulation of anatomical structure morphogenesis GO:0022603 242 0.012
stress activated mapk cascade GO:0051403 52 0.012
regulation of phosphatase activity GO:0010921 3 0.012
single organism behavior GO:0044708 391 0.012
immune system development GO:0002520 57 0.012
positive regulation of multi organism process GO:0043902 40 0.012
regulation of hemocyte proliferation GO:0035206 37 0.012
cellularization GO:0007349 90 0.012
negative regulation of protein metabolic process GO:0051248 85 0.012
maintenance of location in cell GO:0051651 28 0.011
defense response to gram negative bacterium GO:0050829 94 0.011
gtp metabolic process GO:0046039 72 0.011
endocytic recycling GO:0032456 13 0.011
positive regulation of cellular component biogenesis GO:0044089 80 0.011
regulation of secretion GO:0051046 44 0.011
regulation of asymmetric cell division GO:0009786 3 0.011
regulation of proteolysis GO:0030162 87 0.011
dendrite development GO:0016358 204 0.011
endomembrane system organization GO:0010256 119 0.011
localization of cell GO:0051674 257 0.011
purine ribonucleoside monophosphate metabolic process GO:0009167 50 0.011
chromosome organization GO:0051276 360 0.011
hematopoietic progenitor cell differentiation GO:0002244 1 0.011
carbohydrate derivative metabolic process GO:1901135 217 0.011
sensory organ morphogenesis GO:0090596 260 0.011
production of molecular mediator of immune response GO:0002440 46 0.011
synaptic growth at neuromuscular junction GO:0051124 119 0.011
regulation of response to external stimulus GO:0032101 115 0.011
developmental growth GO:0048589 280 0.011
antimicrobial peptide production GO:0002775 46 0.010
cellular response to oxygen containing compound GO:1901701 79 0.010
defense response to virus GO:0051607 23 0.010
neural precursor cell proliferation GO:0061351 75 0.010
macroautophagy GO:0016236 42 0.010
compound eye photoreceptor cell differentiation GO:0001751 140 0.010
convergent extension GO:0060026 2 0.010
forebrain development GO:0030900 2 0.010
gtp catabolic process GO:0006184 72 0.010
response to extracellular stimulus GO:0009991 116 0.010
positive regulation of protein localization to plasma membrane GO:1903078 3 0.010
muscle cell development GO:0055001 50 0.010
positive regulation of molecular function GO:0044093 136 0.010
establishment of protein localization to organelle GO:0072594 62 0.010

Ubc-E2H disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.045
central nervous system disease DOID:331 0 0.014
nervous system disease DOID:863 0 0.014
osteochondrodysplasia DOID:2256 0 0.011
osteogenesis imperfecta DOID:12347 0 0.011
bone development disease DOID:0080006 0 0.011
bone disease DOID:0080001 0 0.011
musculoskeletal system disease DOID:17 0 0.011
connective tissue disease DOID:65 0 0.011