Drosophila melanogaster

78 known processes

sage (Dmel_CG12952)

salivary gland-expressed bHLH

(Aliases: CG12952,Dmel\CG12952,Sage,bHLHc7)

sage biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
developmental growth GO:0048589 280 0.158
Mouse
positive regulation of gene expression GO:0010628 290 0.138
negative regulation of gene expression GO:0010629 387 0.120
Mouse
growth GO:0040007 359 0.119
Mouse
positive regulation of macromolecule metabolic process GO:0010604 405 0.117
negative regulation of macromolecule biosynthetic process GO:0010558 270 0.115
Mouse
positive regulation of cellular biosynthetic process GO:0031328 316 0.113
death GO:0016265 284 0.109
posttranscriptional regulation of gene expression GO:0010608 145 0.088
negative regulation of rna metabolic process GO:0051253 251 0.087
Mouse
positive regulation of transcription dna templated GO:0045893 266 0.086
positive regulation of transcription from rna polymerase ii promoter GO:0045944 204 0.085
positive regulation of macromolecule biosynthetic process GO:0010557 283 0.085
positive regulation of rna metabolic process GO:0051254 271 0.079
vesicle mediated transport GO:0016192 381 0.079
cell death GO:0008219 279 0.078
negative regulation of nucleobase containing compound metabolic process GO:0045934 261 0.077
Mouse
negative regulation of cellular biosynthetic process GO:0031327 277 0.075
Mouse
positive regulation of nitrogen compound metabolic process GO:0051173 354 0.073
transcription from rna polymerase ii promoter GO:0006366 368 0.072
post embryonic appendage morphogenesis GO:0035120 385 0.068
negative regulation of cellular metabolic process GO:0031324 382 0.067
Mouse
immune system process GO:0002376 347 0.067
negative regulation of nucleic acid templated transcription GO:1903507 240 0.067
Mouse
taxis GO:0042330 304 0.065
programmed cell death GO:0012501 257 0.064
protein localization GO:0008104 284 0.061
localization of cell GO:0051674 257 0.061
Mouse
cell proliferation GO:0008283 299 0.061
negative regulation of nitrogen compound metabolic process GO:0051172 265 0.059
Mouse
endocytosis GO:0006897 310 0.059
gland development GO:0048732 191 0.059
wing disc morphogenesis GO:0007472 344 0.058
epithelial cell differentiation GO:0030855 322 0.056
Mouse
appendage development GO:0048736 401 0.056
regulation of cell proliferation GO:0042127 163 0.055
cellular protein modification process GO:0006464 438 0.055
immune response GO:0006955 246 0.055
digestive system development GO:0055123 149 0.054
Mouse
imaginal disc derived appendage development GO:0048737 399 0.053
regulation of programmed cell death GO:0043067 152 0.053
forebrain development GO:0030900 2 0.052
chemotaxis GO:0006935 249 0.050
regulation of cell death GO:0010941 173 0.050
appendage morphogenesis GO:0035107 397 0.049
regulation of transcription from rna polymerase ii promoter GO:0006357 378 0.049
protein modification process GO:0036211 438 0.048
eye morphogenesis GO:0048592 260 0.048
negative regulation of transcription dna templated GO:0045892 237 0.047
Mouse
catabolic process GO:0009056 409 0.046
sensory organ morphogenesis GO:0090596 260 0.046
eye development GO:0001654 323 0.045
response to oxygen containing compound GO:1901700 200 0.045
positive regulation of biosynthetic process GO:0009891 316 0.044
muscle structure development GO:0061061 224 0.044
Mouse
tube morphogenesis GO:0035239 191 0.043
Mouse
dendrite morphogenesis GO:0048813 199 0.043
regulation of growth GO:0040008 233 0.043
positive regulation of nucleic acid templated transcription GO:1903508 266 0.043
response to abiotic stimulus GO:0009628 341 0.041
negative regulation of rna biosynthetic process GO:1902679 240 0.040
Mouse
embryonic morphogenesis GO:0048598 206 0.040
Mouse
chromatin organization GO:0006325 207 0.040
negative regulation of cellular macromolecule biosynthetic process GO:2000113 267 0.040
Mouse
phagocytosis GO:0006909 215 0.040
tube development GO:0035295 244 0.040
Mouse
cellular macromolecule localization GO:0070727 220 0.039
cell motility GO:0048870 251 0.037
Mouse
carboxylic acid metabolic process GO:0019752 92 0.037
regulation of anatomical structure size GO:0090066 163 0.037
regulation of cell differentiation GO:0045595 302 0.036
Mouse
organonitrogen compound metabolic process GO:1901564 318 0.035
body morphogenesis GO:0010171 2 0.035
positive regulation of rna biosynthetic process GO:1902680 266 0.035
chromosome organization GO:0051276 360 0.034
blastoderm segmentation GO:0007350 159 0.034
response to other organism GO:0051707 293 0.034
compound eye morphogenesis GO:0001745 249 0.034
imaginal disc derived appendage morphogenesis GO:0035114 395 0.033
immune effector process GO:0002252 98 0.033
defense response GO:0006952 300 0.033
oxoacid metabolic process GO:0043436 103 0.032
defense response to other organism GO:0098542 225 0.031
regulation of cellular protein metabolic process GO:0032268 243 0.031
cell growth GO:0016049 108 0.031
salivary gland development GO:0007431 162 0.031
eye photoreceptor cell differentiation GO:0001754 145 0.031
cell migration GO:0016477 238 0.031
Mouse
regulation of multicellular organismal development GO:2000026 414 0.031
Mouse
negative regulation of biosynthetic process GO:0009890 277 0.031
Mouse
cellular amino acid metabolic process GO:0006520 61 0.030
spindle organization GO:0007051 253 0.030
positive regulation of nucleobase containing compound metabolic process GO:0045935 332 0.029
small molecule metabolic process GO:0044281 305 0.029
compound eye development GO:0048749 307 0.029
regulation of catalytic activity GO:0050790 185 0.028
embryonic pattern specification GO:0009880 174 0.028
Mouse
positive regulation of multicellular organismal process GO:0051240 143 0.027
Mouse
organic acid metabolic process GO:0006082 103 0.027
oocyte development GO:0048599 124 0.027
cellular ketone metabolic process GO:0042180 24 0.027
dendrite development GO:0016358 204 0.027
regulation of anatomical structure morphogenesis GO:0022603 242 0.027
Mouse
response to external biotic stimulus GO:0043207 293 0.027
cellular catabolic process GO:0044248 372 0.026
embryo development ending in birth or egg hatching GO:0009792 152 0.026
Mouse
regulation of response to stress GO:0080134 200 0.026
sensory perception of mechanical stimulus GO:0050954 72 0.026
establishment of localization in cell GO:0051649 402 0.026
imaginal disc derived wing morphogenesis GO:0007476 337 0.026
organelle fission GO:0048285 340 0.026
response to biotic stimulus GO:0009607 294 0.026
regionalization GO:0003002 416 0.026
Mouse
negative regulation of response to stimulus GO:0048585 258 0.026
Mouse
regulation of protein metabolic process GO:0051246 256 0.025
embryonic development via the syncytial blastoderm GO:0001700 148 0.025
regulation of cellular ketone metabolic process GO:0010565 3 0.025
phosphorylation GO:0016310 294 0.025
gene silencing GO:0016458 138 0.025
regulation of translation GO:0006417 56 0.025
head development GO:0060322 135 0.025
photoreceptor cell differentiation GO:0046530 170 0.024
positive regulation of cellular protein metabolic process GO:0032270 118 0.024
regulation of defense response GO:0031347 102 0.024
imaginal disc pattern formation GO:0007447 91 0.024
regulation of mapk cascade GO:0043408 92 0.024
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 116 0.024
neuron projection guidance GO:0097485 241 0.023
positive regulation of response to stimulus GO:0048584 323 0.023
Mouse
digestive tract development GO:0048565 149 0.023
Mouse
translation GO:0006412 69 0.023
organic substance transport GO:0071702 257 0.023
organic substance catabolic process GO:1901575 308 0.023
spermatid differentiation GO:0048515 114 0.023
mapk cascade GO:0000165 107 0.023
defense response to bacterium GO:0042742 178 0.023
axonogenesis GO:0007409 290 0.022
response to endogenous stimulus GO:0009719 119 0.022
somatic muscle development GO:0007525 66 0.022
response to bacterium GO:0009617 198 0.022
spermatogenesis GO:0007283 200 0.022
regulation of developmental growth GO:0048638 174 0.022
regulation of intracellular signal transduction GO:1902531 236 0.022
regulation of multi organism process GO:0043900 131 0.022
regulation of cell cycle GO:0051726 291 0.022
cellular amine metabolic process GO:0044106 12 0.021
regulation of cell development GO:0060284 215 0.021
response to alcohol GO:0097305 95 0.021
regulation of nervous system development GO:0051960 248 0.021
muscle cell differentiation GO:0042692 103 0.021
Mouse
cell type specific apoptotic process GO:0097285 38 0.021
response to organic substance GO:0010033 284 0.021
intracellular signal transduction GO:0035556 300 0.021
enzyme linked receptor protein signaling pathway GO:0007167 179 0.021
gland morphogenesis GO:0022612 145 0.020
regulation of cellular amino acid metabolic process GO:0006521 0 0.020
regulation of cellular localization GO:0060341 136 0.020
regulation of immune system process GO:0002682 176 0.020
vesicle organization GO:0016050 44 0.020
regulation of cell morphogenesis GO:0022604 163 0.020
nucleoside phosphate metabolic process GO:0006753 162 0.020
negative regulation of signaling GO:0023057 219 0.020
Mouse
cell adhesion GO:0007155 136 0.020
axon guidance GO:0007411 233 0.020
regulation of gene expression epigenetic GO:0040029 128 0.019
protein phosphorylation GO:0006468 169 0.019
regulation of phosphate metabolic process GO:0019220 210 0.019
membrane organization GO:0061024 112 0.019
single organism cellular localization GO:1902580 180 0.018
cellular response to organic substance GO:0071310 132 0.018
neurological system process GO:0050877 358 0.018
signal transduction by phosphorylation GO:0023014 107 0.018
nucleobase containing small molecule metabolic process GO:0055086 174 0.018
tripartite regional subdivision GO:0007351 103 0.018
anterior posterior pattern specification GO:0009952 136 0.018
Mouse
negative regulation of cell communication GO:0010648 223 0.018
Mouse
developmental maturation GO:0021700 172 0.018
aromatic compound catabolic process GO:0019439 166 0.018
intracellular transport GO:0046907 228 0.017
axis specification GO:0009798 167 0.017
Mouse
regulation of localization GO:0032879 275 0.017
response to wounding GO:0009611 94 0.017
axon development GO:0061564 297 0.017
peptidyl amino acid modification GO:0018193 105 0.017
regulation of proteolysis GO:0030162 87 0.017
negative regulation of growth GO:0045926 84 0.017
positive regulation of cellular component organization GO:0051130 156 0.017
regulation of mitotic cell cycle GO:0007346 190 0.017
cellular response to chemical stimulus GO:0070887 199 0.017
regulation of phosphorus metabolic process GO:0051174 210 0.017
anterior posterior axis specification GO:0009948 109 0.016
Mouse
negative regulation of transcription from rna polymerase ii promoter GO:0000122 119 0.016
lipid metabolic process GO:0006629 121 0.016
leg disc development GO:0035218 92 0.016
organic cyclic compound catabolic process GO:1901361 168 0.016
negative regulation of cell differentiation GO:0045596 143 0.016
Mouse
positive regulation of cell motility GO:2000147 3 0.016
ribonucleotide metabolic process GO:0009259 145 0.016
positive regulation of cell communication GO:0010647 250 0.016
Mouse
organophosphate metabolic process GO:0019637 195 0.016
salivary gland morphogenesis GO:0007435 145 0.016
homeostatic process GO:0042592 199 0.016
regulation of organ growth GO:0046620 42 0.015
response to radiation GO:0009314 155 0.015
cellular protein localization GO:0034613 160 0.015
apoptotic process GO:0006915 159 0.015
muscle organ development GO:0007517 127 0.015
retina development in camera type eye GO:0060041 4 0.015
negative regulation of developmental growth GO:0048640 64 0.015
purine containing compound metabolic process GO:0072521 155 0.015
central nervous system development GO:0007417 201 0.015
regulation of cellular amine metabolic process GO:0033238 3 0.015
detection of external stimulus GO:0009581 66 0.015
renal system development GO:0072001 72 0.014
positive regulation of protein metabolic process GO:0051247 128 0.014
wound healing GO:0042060 75 0.014
macromolecular complex assembly GO:0065003 256 0.014
regulation of response to external stimulus GO:0032101 115 0.014
eye photoreceptor cell development GO:0042462 81 0.014
response to nutrient levels GO:0031667 114 0.014
regulation of cell adhesion GO:0030155 27 0.014
positive regulation of molecular function GO:0044093 136 0.014
nuclear division GO:0000280 332 0.014
amine metabolic process GO:0009308 12 0.014
proteolysis GO:0006508 192 0.014
neuron recognition GO:0008038 101 0.014
positive regulation of transport GO:0051050 92 0.014
morphogenesis of an epithelium GO:0002009 276 0.014
Mouse
synapse assembly GO:0007416 143 0.014
regulation of tube size GO:0035150 46 0.014
mesoderm development GO:0007498 78 0.014
Mouse
dna packaging GO:0006323 91 0.014
embryonic axis specification GO:0000578 107 0.014
Mouse
organ growth GO:0035265 56 0.014
Mouse
segmentation GO:0035282 207 0.014
Mouse
negative regulation of cell proliferation GO:0008285 69 0.014
positive regulation of signal transduction GO:0009967 223 0.014
Mouse
histolysis GO:0007559 102 0.014
positive regulation of programmed cell death GO:0043068 62 0.014
memory GO:0007613 94 0.013
regulation of hydrolase activity GO:0051336 97 0.013
epithelial cell development GO:0002064 274 0.013
protein transport GO:0015031 155 0.013
nucleotide metabolic process GO:0009117 161 0.013
negative regulation of developmental process GO:0051093 201 0.013
Mouse
instar larval development GO:0002168 55 0.013
regulation of molecular function GO:0065009 217 0.013
single organism biosynthetic process GO:0044711 206 0.013
response to extracellular stimulus GO:0009991 116 0.013
positive regulation of signaling GO:0023056 243 0.013
Mouse
ribonucleoside catabolic process GO:0042454 112 0.013
male gamete generation GO:0048232 201 0.013
mitotic cell cycle phase transition GO:0044772 138 0.013
oocyte differentiation GO:0009994 145 0.013
antimicrobial humoral response GO:0019730 99 0.013
single organism intracellular transport GO:1902582 207 0.013
columnar cuboidal epithelial cell development GO:0002066 249 0.013
sensory perception GO:0007600 196 0.013
positive regulation of developmental process GO:0051094 143 0.013
Mouse
regulation of locomotion GO:0040012 42 0.013
actin cytoskeleton organization GO:0030036 206 0.013
regulation of neuron differentiation GO:0045664 103 0.013
exocrine system development GO:0035272 162 0.013
compound eye photoreceptor cell differentiation GO:0001751 140 0.013
rna localization GO:0006403 115 0.013
rna processing GO:0006396 147 0.013
cell cell signaling involved in cell fate commitment GO:0045168 210 0.013
Mouse
cellular response to oxygen containing compound GO:1901701 79 0.012
histone modification GO:0016570 106 0.012
positive regulation of cell death GO:0010942 69 0.012
positive regulation of hydrolase activity GO:0051345 78 0.012
cellular nitrogen compound catabolic process GO:0044270 165 0.012
ras protein signal transduction GO:0007265 88 0.012
meiotic cell cycle GO:0051321 171 0.012
response to temperature stimulus GO:0009266 106 0.012
regulation of cell projection organization GO:0031344 92 0.012
regulation of phosphorylation GO:0042325 147 0.012
cell cycle phase transition GO:0044770 140 0.012
single organismal cell cell adhesion GO:0016337 45 0.012
regulation of cell growth GO:0001558 43 0.012
cell maturation GO:0048469 144 0.012
compound eye photoreceptor fate commitment GO:0001752 36 0.012
regulation of cellular catabolic process GO:0031329 157 0.012
innate immune response GO:0045087 144 0.012
cellularization GO:0007349 90 0.012
response to nitrogen compound GO:1901698 90 0.012
carbohydrate derivative metabolic process GO:1901135 217 0.012
negative regulation of signal transduction GO:0009968 206 0.012
Mouse
spermatid development GO:0007286 98 0.012
negative regulation of gene expression epigenetic GO:0045814 77 0.012
cellular component assembly involved in morphogenesis GO:0010927 151 0.012
vitamin metabolic process GO:0006766 2 0.012
single organism membrane organization GO:0044802 93 0.012
lateral inhibition GO:0046331 206 0.012
nucleoside metabolic process GO:0009116 127 0.011
regulation of hormone levels GO:0010817 40 0.011
regulation of neuron projection development GO:0010975 69 0.011
larval behavior GO:0030537 42 0.011
positive regulation of intracellular signal transduction GO:1902533 116 0.011
regulation of neurogenesis GO:0050767 158 0.011
organonitrogen compound catabolic process GO:1901565 128 0.011
hindbrain development GO:0030902 2 0.011
tissue morphogenesis GO:0048729 297 0.011
Mouse
dorsal ventral pattern formation GO:0009953 133 0.011
chorion containing eggshell formation GO:0007304 105 0.011
wing disc pattern formation GO:0035222 66 0.011
establishment of protein localization GO:0045184 163 0.011
positive regulation of phosphate metabolic process GO:0045937 139 0.011
heterocycle catabolic process GO:0046700 166 0.011
epithelium migration GO:0090132 148 0.011
mitotic nuclear division GO:0007067 213 0.011
single organism catabolic process GO:0044712 228 0.011
larval development GO:0002164 104 0.011
digestive tract morphogenesis GO:0048546 127 0.011
Mouse
connective tissue development GO:0061448 3 0.011
photoreceptor cell development GO:0042461 96 0.011
positive regulation of cellular amino acid metabolic process GO:0045764 0 0.011
regulation of cellular component biogenesis GO:0044087 201 0.011
aging GO:0007568 143 0.011
mesenchymal cell differentiation GO:0048762 1 0.011
regulation of cell cycle process GO:0010564 181 0.011
multi organism behavior GO:0051705 175 0.011
macromolecule catabolic process GO:0009057 161 0.011
humoral immune response GO:0006959 117 0.011
regulation of apoptotic process GO:0042981 130 0.011
positive regulation of phosphorus metabolic process GO:0010562 139 0.011
negative regulation of cell death GO:0060548 81 0.011
negative regulation of phosphorylation GO:0042326 35 0.010
developmental programmed cell death GO:0010623 138 0.010
stem cell proliferation GO:0072089 88 0.010
epithelial cell migration GO:0010631 148 0.010
neuron fate commitment GO:0048663 50 0.010
purine nucleoside metabolic process GO:0042278 127 0.010
glycosyl compound metabolic process GO:1901657 127 0.010
single organism behavior GO:0044708 391 0.010
detection of abiotic stimulus GO:0009582 66 0.010
purine containing compound catabolic process GO:0072523 112 0.010
cellular response to abiotic stimulus GO:0071214 58 0.010
dna metabolic process GO:0006259 227 0.010
regulation of catabolic process GO:0009894 170 0.010
ribonucleotide catabolic process GO:0009261 109 0.010
nucleoside catabolic process GO:0009164 112 0.010
actin filament based process GO:0030029 220 0.010
reproductive system development GO:0061458 74 0.010

sage disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.084
musculoskeletal system disease DOID:17 0 0.019
nervous system disease DOID:863 0 0.015
connective tissue disease DOID:65 0 0.012
disease of metabolism DOID:0014667 0 0.010