Drosophila melanogaster

117 known processes

Lim1 (Dmel_CG11354)

CG11354 gene product from transcript CG11354-RA

(Aliases: BcDNA:GH04929,lim1,dLim1,Lim,Dmel\CG11354,CG11354,Dlim1,CG10760,dlim-1,dlim1)

Lim1 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
leg disc morphogenesis GO:0007478 80 0.873
leg disc development GO:0035218 92 0.816
muscle cell fate commitment GO:0042693 14 0.813
Fly
imaginal disc derived leg morphogenesis GO:0007480 80 0.778
appendage morphogenesis GO:0035107 397 0.756
eye antennal disc development GO:0035214 60 0.741
post embryonic appendage morphogenesis GO:0035120 385 0.736
male courtship behavior GO:0008049 63 0.711
regulation of nervous system development GO:0051960 248 0.706
Mouse
dendrite development GO:0016358 204 0.701
Fly
imaginal disc derived appendage development GO:0048737 399 0.662
appendage development GO:0048736 401 0.648
positive regulation of transcription dna templated GO:0045893 266 0.626
regulation of transcription from rna polymerase ii promoter GO:0006357 378 0.623
Fly
antennal development GO:0007469 25 0.608
imaginal disc derived appendage morphogenesis GO:0035114 395 0.598
developmental growth GO:0048589 280 0.590
Mouse
terminal region determination GO:0007362 25 0.587
Fly
positive regulation of nucleobase containing compound metabolic process GO:0045935 332 0.563
positive regulation of macromolecule biosynthetic process GO:0010557 283 0.560
regulation of neuron differentiation GO:0045664 103 0.516
mating GO:0007618 120 0.509
imaginal disc derived leg segmentation GO:0036011 26 0.473
Fly
axon development GO:0061564 297 0.408
Mouse Worm Fly
male courtship behavior veined wing vibration GO:0016545 21 0.397
regulation of r7 cell differentiation GO:0045676 15 0.390
muscle cell differentiation GO:0042692 103 0.366
Fly
neuron projection guidance GO:0097485 241 0.364
Mouse Fly
male courtship behavior veined wing extension GO:0048065 22 0.357
positive regulation of rna metabolic process GO:0051254 271 0.339
dendrite guidance GO:0070983 21 0.326
Fly
torso signaling pathway GO:0008293 21 0.319
Fly
negative regulation of cellular metabolic process GO:0031324 382 0.316
retinal cone cell differentiation GO:0042670 2 0.290
imaginal disc derived wing morphogenesis GO:0007476 337 0.288
muscle structure development GO:0061061 224 0.284
Fly
organ formation GO:0048645 39 0.278
positive regulation of rna biosynthetic process GO:1902680 266 0.274
positive regulation of nucleic acid templated transcription GO:1903508 266 0.266
camera type eye development GO:0043010 4 0.264
Mouse
positive regulation of cellular biosynthetic process GO:0031328 316 0.259
leg disc proximal distal pattern formation GO:0007479 9 0.246
mating behavior sex discrimination GO:0048047 7 0.243
regulation of photoreceptor cell differentiation GO:0046532 34 0.239
positive regulation of macromolecule metabolic process GO:0010604 405 0.237
regulation of anatomical structure morphogenesis GO:0022603 242 0.222
Mouse
segmentation GO:0035282 207 0.220
Mouse Fly
camera type eye photoreceptor cell differentiation GO:0060219 2 0.216
dendrite morphogenesis GO:0048813 199 0.209
Fly
regulation of neurogenesis GO:0050767 158 0.206
regulation of cell fate commitment GO:0010453 29 0.202
positive regulation of nitrogen compound metabolic process GO:0051173 354 0.196
regulation of epithelial cell proliferation GO:0050678 4 0.195
specification of organ identity GO:0010092 3 0.195
male courtship behavior veined wing generated song production GO:0045433 20 0.189
positive regulation of developmental process GO:0051094 143 0.182
Mouse Worm
negative regulation of transcription dna templated GO:0045892 237 0.173
neuron fate commitment GO:0048663 50 0.173
regulation of neuron projection development GO:0010975 69 0.169
appendage segmentation GO:0035285 26 0.168
Fly
mushroom body development GO:0016319 70 0.166
ameboidal type cell migration GO:0001667 151 0.164
negative regulation of rna metabolic process GO:0051253 251 0.153
transcription from rna polymerase ii promoter GO:0006366 368 0.152
Mouse Fly
regulation of cell fate specification GO:0042659 27 0.151
negative regulation of nucleic acid templated transcription GO:1903507 240 0.138
negative regulation of gene expression GO:0010629 387 0.133
axonogenesis GO:0007409 290 0.129
Mouse Fly
eye antennal disc morphogenesis GO:0007455 34 0.129
wing disc morphogenesis GO:0007472 344 0.125
negative regulation of nucleobase containing compound metabolic process GO:0045934 261 0.123
positive regulation of biosynthetic process GO:0009891 316 0.115
regulation of heart morphogenesis GO:2000826 3 0.115
positive regulation of transcription from rna polymerase ii promoter GO:0045944 204 0.111
Fly
aggressive behavior GO:0002118 63 0.109
endocytosis GO:0006897 310 0.107
antennal morphogenesis GO:0048800 14 0.107
specification of symmetry GO:0009799 13 0.107
regulation of organ morphogenesis GO:2000027 78 0.106
Mouse
courtship behavior GO:0007619 68 0.100
camera type eye morphogenesis GO:0048593 2 0.098
Mouse
cardiovascular system development GO:0072358 82 0.096
Fly
cell fate specification GO:0001708 71 0.095
Worm Fly
negative regulation of biosynthetic process GO:0009890 277 0.093
reproductive system development GO:0061458 74 0.093
Mouse
cell motility GO:0048870 251 0.092
Mouse Worm
single organism behavior GO:0044708 391 0.089
central nervous system development GO:0007417 201 0.087
Zebrafish Mouse
imaginal disc derived leg joint morphogenesis GO:0016348 15 0.084
head development GO:0060322 135 0.083
Zebrafish Mouse
regionalization GO:0003002 416 0.080
embryonic organ development GO:0048568 50 0.080
Mouse
cranial nerve development GO:0021545 1 0.079
epithelial tube morphogenesis GO:0060562 88 0.075
Mouse
determination of left right symmetry GO:0007368 9 0.075
eye morphogenesis GO:0048592 260 0.074
Mouse
zygotic determination of anterior posterior axis embryo GO:0007354 27 0.073
Fly
regulation of multicellular organismal development GO:2000026 414 0.070
Mouse Worm
mating behavior GO:0007617 106 0.070
embryonic heart tube development GO:0035050 22 0.070
anterior posterior pattern specification GO:0009952 136 0.069
Mouse Fly
chemotaxis GO:0006935 249 0.068
Mouse Fly
forebrain development GO:0030900 2 0.067
Zebrafish Mouse
development of primary female sexual characteristics GO:0046545 12 0.067
positive regulation of cell communication GO:0010647 250 0.066
reproductive behavior GO:0019098 122 0.065
Worm
tube morphogenesis GO:0035239 191 0.064
Mouse
positive regulation of phosphorus metabolic process GO:0010562 139 0.062
photoreceptor cell fate commitment GO:0046552 41 0.062
kidney morphogenesis GO:0060993 3 0.061
Mouse Rat
homeostatic process GO:0042592 199 0.060
Fly
regulation of cell projection organization GO:0031344 92 0.059
negative regulation of cellular macromolecule biosynthetic process GO:2000113 267 0.059
determination of bilateral symmetry GO:0009855 13 0.058
synapse assembly GO:0007416 143 0.056
vesicle mediated transport GO:0016192 381 0.055
localization of cell GO:0051674 257 0.054
Mouse Worm
multi organism behavior GO:0051705 175 0.053
Worm
positive regulation of multicellular organismal process GO:0051240 143 0.053
Mouse Worm
male mating behavior GO:0060179 70 0.053
muscle organ development GO:0007517 127 0.052
Fly
negative regulation of rna biosynthetic process GO:1902679 240 0.052
regulation of cell cycle GO:0051726 291 0.052
Fly
negative regulation of response to stimulus GO:0048585 258 0.051
phosphorylation GO:0016310 294 0.051
regulation of cell death GO:0010941 173 0.050
cardiocyte differentiation GO:0035051 29 0.049
negative regulation of nitrogen compound metabolic process GO:0051172 265 0.049
telencephalon development GO:0021537 2 0.048
Mouse
eye development GO:0001654 323 0.048
neuron fate specification GO:0048665 12 0.048
establishment of localization in cell GO:0051649 402 0.048
dorsal ventral pattern formation GO:0009953 133 0.048
Mouse Fly
embryonic pattern specification GO:0009880 174 0.047
Mouse Fly
negative regulation of cell differentiation GO:0045596 143 0.046
regulation of cell proliferation GO:0042127 163 0.046
Mouse
axon guidance GO:0007411 233 0.045
Mouse Fly
regulation of imaginal disc derived wing size GO:0044719 20 0.045
cellular protein modification process GO:0006464 438 0.045
sex differentiation GO:0007548 81 0.045
Mouse
regulation of anatomical structure size GO:0090066 163 0.044
retina morphogenesis in camera type eye GO:0060042 2 0.044
Mouse
multi multicellular organism process GO:0044706 123 0.043
Worm
gastrulation GO:0007369 70 0.043
Mouse
morphogenesis of an epithelium GO:0002009 276 0.043
Mouse Fly
lymph gland development GO:0048542 28 0.043
Fly
regulation of phosphorus metabolic process GO:0051174 210 0.043
positive regulation of phosphate metabolic process GO:0045937 139 0.042
photoreceptor cell fate specification GO:0043704 9 0.042
heart development GO:0007507 82 0.041
Fly
cell fate determination GO:0001709 91 0.041
Fly
regulation of cell development GO:0060284 215 0.040
regulation of phosphate metabolic process GO:0019220 210 0.040
positive regulation of axonogenesis GO:0050772 2 0.039
convergent extension GO:0060026 2 0.039
protein phosphorylation GO:0006468 169 0.038
leg disc pattern formation GO:0035223 11 0.038
cell fate commitment involved in pattern specification GO:0060581 31 0.038
Fly
neuron projection extension GO:1990138 32 0.038
tissue morphogenesis GO:0048729 297 0.037
Mouse Fly
regulation of cellular protein metabolic process GO:0032268 243 0.037
macromolecular complex assembly GO:0065003 256 0.037
synaptic growth at neuromuscular junction GO:0051124 119 0.036
mesodermal cell fate specification GO:0007501 2 0.036
neuroblast differentiation GO:0014016 29 0.036
cell division GO:0051301 248 0.036
positive regulation of cellular component biogenesis GO:0044089 80 0.035
anterior posterior axis specification embryo GO:0008595 103 0.034
Fly
imaginal disc growth GO:0007446 37 0.034
negative regulation of multicellular organismal process GO:0051241 142 0.034
sensory organ morphogenesis GO:0090596 260 0.034
Mouse
compound eye morphogenesis GO:0001745 249 0.034
regulation of cell morphogenesis GO:0022604 163 0.033
cardiac cell fate commitment GO:0060911 17 0.033
reproductive structure development GO:0048608 74 0.033
Mouse
mesenchyme development GO:0060485 9 0.033
phagocytosis GO:0006909 215 0.033
cell fate specification involved in pattern specification GO:0060573 8 0.032
Fly
regulation of organ formation GO:0003156 3 0.032
imaginal disc pattern formation GO:0007447 91 0.031
biological adhesion GO:0022610 138 0.031
heart formation GO:0060914 6 0.031
outflow tract morphogenesis GO:0003151 4 0.030
ocellus development GO:0008056 4 0.030
neuron recognition GO:0008038 101 0.030
Worm
rna polymerase ii transcriptional preinitiation complex assembly GO:0051123 20 0.030
regulation of response to stress GO:0080134 200 0.029
regulation of intracellular signal transduction GO:1902531 236 0.028
photoreceptor cell differentiation GO:0046530 170 0.027
hair cell differentiation GO:0035315 47 0.027
heart morphogenesis GO:0003007 32 0.027
neural retina development GO:0003407 4 0.026
Mouse
adult locomotory behavior GO:0008344 76 0.026
negative regulation of molecular function GO:0044092 51 0.026
Fly
negative regulation of transcription from rna polymerase ii promoter GO:0000122 119 0.026
compound eye photoreceptor cell differentiation GO:0001751 140 0.026
positive regulation of epithelial cell differentiation GO:0030858 1 0.025
Mouse
imaginal disc derived wing margin morphogenesis GO:0008587 41 0.025
epithelial cell development GO:0002064 274 0.025
regulation of cellular ketone metabolic process GO:0010565 3 0.025
chaeta morphogenesis GO:0008407 42 0.024
Fly
nuclear division GO:0000280 332 0.024
negative regulation of signal transduction GO:0009968 206 0.024
regulation of cellular component biogenesis GO:0044087 201 0.024
programmed cell death GO:0012501 257 0.024
carbohydrate derivative metabolic process GO:1901135 217 0.024
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 116 0.023
Fly
organ growth GO:0035265 56 0.023
negative regulation of nervous system development GO:0051961 92 0.023
regulation of hormone levels GO:0010817 40 0.023
notch signaling pathway GO:0007219 120 0.023
connective tissue development GO:0061448 3 0.023
positive regulation of nervous system development GO:0051962 69 0.023
Mouse
signal release GO:0023061 49 0.023
mesenchymal cell differentiation GO:0048762 1 0.023
regulation of synapse assembly GO:0051963 94 0.022
limb morphogenesis GO:0035108 1 0.022
stem cell proliferation GO:0072089 88 0.022
retina development in camera type eye GO:0060041 4 0.022
Mouse
axon extension GO:0048675 32 0.021
regulation of cell morphogenesis involved in differentiation GO:0010769 61 0.021
axis specification GO:0009798 167 0.021
Mouse Fly
mesoderm development GO:0007498 78 0.021
wing disc pattern formation GO:0035222 66 0.021
Fly
notum cell fate specification GO:0035310 5 0.020
Fly
multicellular organismal reproductive behavior GO:0033057 110 0.020
Worm
positive regulation of signaling GO:0023056 243 0.020
chaeta development GO:0022416 97 0.020
Fly
regulation of axonogenesis GO:0050770 32 0.020
dna templated transcriptional preinitiation complex assembly GO:0070897 20 0.020
r7 cell differentiation GO:0045466 43 0.020
gland development GO:0048732 191 0.019
Fly
negative regulation of neurogenesis GO:0050768 53 0.019
positive regulation of cell proliferation GO:0008284 47 0.019
Mouse
enzyme linked receptor protein signaling pathway GO:0007167 179 0.019
Fly
skin development GO:0043588 65 0.019
regulation of programmed cell death GO:0043067 152 0.019
positive regulation of signal transduction GO:0009967 223 0.019
positive regulation of gene expression GO:0010628 290 0.019
anterior posterior axis specification GO:0009948 109 0.019
Mouse Fly
compound eye development GO:0048749 307 0.018
death GO:0016265 284 0.018
Fly
aging GO:0007568 143 0.018
mesenchymal cell development GO:0014031 1 0.018
endoderm formation GO:0001706 3 0.018
Mouse
nephron tubule morphogenesis GO:0072078 3 0.018
Mouse
positive regulation of phosphorylation GO:0042327 87 0.018
regulation of insulin like growth factor receptor signaling pathway GO:0043567 3 0.018
vesicle organization GO:0016050 44 0.018
cardiac cell fate determination GO:0060913 3 0.018
gonad development GO:0008406 50 0.018
muscle tissue morphogenesis GO:0060415 2 0.018
negative regulation of sequence specific dna binding transcription factor activity GO:0043433 4 0.018
Fly
epithelial cell morphogenesis GO:0003382 25 0.018
negative regulation of neuron death GO:1901215 18 0.017
positive regulation of neuron differentiation GO:0045666 26 0.017
negative regulation of cellular biosynthetic process GO:0031327 277 0.017
epithelial cell differentiation GO:0030855 322 0.017
Mouse
cell adhesion GO:0007155 136 0.017
regulation of mapk cascade GO:0043408 92 0.017
organic substance transport GO:0071702 257 0.017
single organism intracellular transport GO:1902582 207 0.017
positive regulation of response to stimulus GO:0048584 323 0.016
regulation of molecular function GO:0065009 217 0.016
Fly
negative regulation of macromolecule biosynthetic process GO:0010558 270 0.016
morphogenesis of a branching epithelium GO:0061138 45 0.016
Mouse
protein complex assembly GO:0006461 200 0.015
cell proliferation GO:0008283 299 0.015
Mouse
regulation of imaginal disc growth GO:0045570 26 0.015
actin filament based process GO:0030029 220 0.015
adult behavior GO:0030534 137 0.015
female sex differentiation GO:0046660 20 0.015
Mouse
dorsal ventral axis specification GO:0009950 66 0.015
intracellular protein transport GO:0006886 104 0.014
negative regulation of cell fate specification GO:0009996 15 0.014
negative regulation of sequestering of calcium ion GO:0051283 2 0.014
regulation of developmental growth GO:0048638 174 0.014
positive regulation of intracellular signal transduction GO:1902533 116 0.014
positive regulation of cell differentiation GO:0045597 64 0.014
Mouse
striated muscle tissue development GO:0014706 27 0.014
negative regulation of signaling GO:0023057 219 0.014
regulation of behavior GO:0050795 75 0.014
mesodermal cell fate commitment GO:0001710 7 0.013
regulation of humoral immune response GO:0002920 51 0.013
regulation of epithelial cell differentiation GO:0030856 4 0.013
Mouse
larval somatic muscle development GO:0007526 19 0.013
Fly
single organism nuclear import GO:1902593 51 0.013
developmental cell growth GO:0048588 52 0.013
anterior malpighian tubule development GO:0061327 12 0.013
positive regulation of neurogenesis GO:0050769 41 0.013
ectodermal placode morphogenesis GO:0071697 4 0.013
regulation of growth GO:0040008 233 0.013
regulation of phosphorylation GO:0042325 147 0.013
ras protein signal transduction GO:0007265 88 0.013
germ band shortening GO:0007390 19 0.013
Fly
ectodermal placode development GO:0071696 4 0.013
cell recognition GO:0008037 102 0.013
Worm
small gtpase mediated signal transduction GO:0007264 88 0.012
cell death GO:0008219 279 0.012
regulation of mitotic cell cycle GO:0007346 190 0.012
eye photoreceptor cell differentiation GO:0001754 145 0.012
regulation of dendrite development GO:0050773 37 0.012
social behavior GO:0035176 4 0.012
positive regulation of cell development GO:0010720 61 0.012
signal transduction by phosphorylation GO:0023014 107 0.012
regulation of intracellular transport GO:0032386 64 0.012
embryonic axis specification GO:0000578 107 0.012
Mouse Fly
anatomical structure homeostasis GO:0060249 97 0.011
Fly
cardiac muscle cell differentiation GO:0055007 4 0.011
muscle organ morphogenesis GO:0048644 7 0.011
tripartite regional subdivision GO:0007351 103 0.011
Fly
intraspecies interaction between organisms GO:0051703 4 0.011
determination of dorsal ventral asymmetry GO:0048262 3 0.011
histolysis GO:0007559 102 0.011
Fly
negative regulation of smoothened signaling pathway GO:0045879 16 0.010
regulation of dendrite morphogenesis GO:0048814 28 0.010
equator specification GO:0045317 4 0.010
body morphogenesis GO:0010171 2 0.010
amide transport GO:0042886 10 0.010
organelle fission GO:0048285 340 0.010
protein kinase b signaling GO:0043491 1 0.010
cell cell signaling involved in cell fate commitment GO:0045168 210 0.010
cellular ketone metabolic process GO:0042180 24 0.010
regulation of compound eye cone cell fate specification GO:0042682 4 0.010

Lim1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.051
cardiovascular system disease DOID:1287 0 0.051
cancer DOID:162 0 0.014
disease of cellular proliferation DOID:14566 0 0.014
organ system cancer DOID:0050686 0 0.014