Drosophila melanogaster

15 known processes

l(2)37Cb (Dmel_CG10689)

lethal (2) 37Cb

(Aliases: Cb,CG10689,cg10689,Dmel\CG10689,l(2)E104)

l(2)37Cb biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
positive regulation of nucleobase containing compound metabolic process GO:0045935 332 0.787
dna metabolic process GO:0006259 227 0.593
embryo development ending in birth or egg hatching GO:0009792 152 0.354
Worm
pigmentation GO:0043473 75 0.224
positive regulation of transcription dna templated GO:0045893 266 0.223
rna splicing via transesterification reactions with bulged adenosine as nucleophile GO:0000377 73 0.190
Yeast
positive regulation of macromolecule metabolic process GO:0010604 405 0.187
positive regulation of nitrogen compound metabolic process GO:0051173 354 0.176
cellular macromolecular complex assembly GO:0034622 153 0.172
Yeast
regionalization GO:0003002 416 0.161
chromosome organization GO:0051276 360 0.153
protein acetylation GO:0006473 39 0.136
mrna processing GO:0006397 104 0.133
Yeast
rna processing GO:0006396 147 0.131
Yeast
ncrna 3 end processing GO:0043628 17 0.131
regulation of dna metabolic process GO:0051052 34 0.124
mrna metabolic process GO:0016071 124 0.123
Yeast
larval development GO:0002164 104 0.120
Worm
positive regulation of biosynthetic process GO:0009891 316 0.119
internal protein amino acid acetylation GO:0006475 38 0.117
peptidyl lysine modification GO:0018205 57 0.116
positive regulation of cellular biosynthetic process GO:0031328 316 0.115
regulation of programmed cell death GO:0043067 152 0.114
cell proliferation GO:0008283 299 0.111
Worm
endocytosis GO:0006897 310 0.107
positive regulation of nucleic acid templated transcription GO:1903508 266 0.104
snrna 3 end processing GO:0034472 14 0.103
positive regulation of gene expression GO:0010628 290 0.102
cellular protein modification process GO:0006464 438 0.099
positive regulation of transcription from rna polymerase ii promoter GO:0045944 204 0.095
protein dna complex subunit organization GO:0071824 86 0.093
developmental pigmentation GO:0048066 68 0.092
nucleobase containing compound catabolic process GO:0034655 165 0.090
Yeast
small molecule metabolic process GO:0044281 305 0.089
Yeast
death GO:0016265 284 0.085
organonitrogen compound metabolic process GO:1901564 318 0.085
Yeast
snrna metabolic process GO:0016073 14 0.083
protein acylation GO:0043543 42 0.082
positive regulation of rna metabolic process GO:0051254 271 0.080
regulation of dna templated transcription elongation GO:0032784 17 0.078
rna splicing via transesterification reactions GO:0000375 73 0.078
Yeast
apoptotic process GO:0006915 159 0.076
regulation of organelle organization GO:0033043 196 0.072
Worm
immune system process GO:0002376 347 0.071
macromolecular complex assembly GO:0065003 256 0.070
Yeast
cellular catabolic process GO:0044248 372 0.067
Yeast
meiotic cell cycle GO:0051321 171 0.067
Worm
negative regulation of gene expression GO:0010629 387 0.065
regulation of cell cycle GO:0051726 291 0.065
Worm
positive regulation of molecular function GO:0044093 136 0.064
protein dna complex assembly GO:0065004 63 0.063
embryonic morphogenesis GO:0048598 206 0.062
Zebrafish Worm
cellular nitrogen compound catabolic process GO:0044270 165 0.059
Yeast
meiotic nuclear division GO:0007126 151 0.058
Worm
heterocycle catabolic process GO:0046700 166 0.058
Yeast
histone modification GO:0016570 106 0.053
chromatin modification GO:0016568 147 0.053
exocrine system development GO:0035272 162 0.052
programmed cell death GO:0012501 257 0.052
positive regulation of rna biosynthetic process GO:1902680 266 0.052
chromatin organization GO:0006325 207 0.051
dendrite morphogenesis GO:0048813 199 0.051
ncrna metabolic process GO:0034660 43 0.051
Yeast
organophosphate metabolic process GO:0019637 195 0.051
Yeast
carbohydrate derivative metabolic process GO:1901135 217 0.049
Yeast
response to other organism GO:0051707 293 0.049
cell maturation GO:0048469 144 0.048
aromatic compound catabolic process GO:0019439 166 0.048
Yeast
negative regulation of cellular metabolic process GO:0031324 382 0.047
dna replication GO:0006260 48 0.047
regulation of protein metabolic process GO:0051246 256 0.046
positive regulation of macromolecule biosynthetic process GO:0010557 283 0.044
stem cell maintenance GO:0019827 67 0.044
gene silencing GO:0016458 138 0.044
snrna processing GO:0016180 14 0.044
nucleotide metabolic process GO:0009117 161 0.043
Yeast
internal peptidyl lysine acetylation GO:0018393 38 0.043
response to abiotic stimulus GO:0009628 341 0.042
imaginal disc derived wing morphogenesis GO:0007476 337 0.041
intracellular signal transduction GO:0035556 300 0.040
negative regulation of rna metabolic process GO:0051253 251 0.039
single organism biosynthetic process GO:0044711 206 0.039
rna 3 end processing GO:0031123 45 0.039
organic acid metabolic process GO:0006082 103 0.038
positive regulation of cellular component organization GO:0051130 156 0.037
transcription from rna polymerase ii promoter GO:0006366 368 0.037
protein modification process GO:0036211 438 0.036
response to external biotic stimulus GO:0043207 293 0.035
regulation of mrna splicing via spliceosome GO:0048024 64 0.034
catabolic process GO:0009056 409 0.034
Yeast
regulation of mitotic cell cycle phase transition GO:1901990 130 0.034
cell death GO:0008219 279 0.034
cellular response to dna damage stimulus GO:0006974 223 0.033
regulation of molecular function GO:0065009 217 0.033
positive regulation of cell communication GO:0010647 250 0.033
axon development GO:0061564 297 0.033
organelle assembly GO:0070925 198 0.033
histone acetylation GO:0016573 38 0.032
positive regulation of catalytic activity GO:0043085 118 0.032
negative regulation of nitrogen compound metabolic process GO:0051172 265 0.032
rna splicing GO:0008380 83 0.032
Yeast
peptidyl lysine acetylation GO:0018394 39 0.031
response to bacterium GO:0009617 198 0.031
brain development GO:0007420 120 0.031
cellular amino acid metabolic process GO:0006520 61 0.031
response to lipopolysaccharide GO:0032496 4 0.031
vesicle mediated transport GO:0016192 381 0.030
regulation of mrna processing GO:0050684 71 0.030
homeostatic process GO:0042592 199 0.030
carboxylic acid metabolic process GO:0019752 92 0.029
positive regulation of cellular protein metabolic process GO:0032270 118 0.029
central nervous system development GO:0007417 201 0.029
taxis GO:0042330 304 0.029
response to biotic stimulus GO:0009607 294 0.028
nucleoside phosphate metabolic process GO:0006753 162 0.028
Yeast
imaginal disc derived appendage morphogenesis GO:0035114 395 0.028
oxoacid metabolic process GO:0043436 103 0.028
regulation of apoptotic process GO:0042981 130 0.028
peptidyl amino acid modification GO:0018193 105 0.027
organic substance catabolic process GO:1901575 308 0.027
Yeast
rna transport GO:0050658 46 0.027
dna packaging GO:0006323 91 0.027
rna localization GO:0006403 115 0.026
dna repair GO:0006281 54 0.026
regulation of chromosome organization GO:0033044 64 0.026
antimicrobial humoral response GO:0019730 99 0.025
intracellular transport GO:0046907 228 0.025
innate immune response GO:0045087 144 0.025
purine ribonucleotide metabolic process GO:0009150 145 0.025
Yeast
negative regulation of macromolecule biosynthetic process GO:0010558 270 0.025
phagocytosis GO:0006909 215 0.025
glycosyl compound metabolic process GO:1901657 127 0.025
Yeast
dna templated transcription elongation GO:0006354 18 0.025
neuron projection guidance GO:0097485 241 0.024
imaginal disc derived appendage development GO:0048737 399 0.024
tube morphogenesis GO:0035239 191 0.024
Zebrafish
immune response GO:0006955 246 0.024
positive regulation of hydrolase activity GO:0051345 78 0.024
regulation of anatomical structure morphogenesis GO:0022603 242 0.024
negative regulation of transcription from rna polymerase ii promoter GO:0000122 119 0.023
post embryonic appendage morphogenesis GO:0035120 385 0.023
regulation of intracellular signal transduction GO:1902531 236 0.023
regulation of developmental pigmentation GO:0048070 24 0.023
axon guidance GO:0007411 233 0.023
hindbrain development GO:0030902 2 0.022
response to temperature stimulus GO:0009266 106 0.022
rna polyadenylation GO:0043631 12 0.022
regulation of small gtpase mediated signal transduction GO:0051056 93 0.022
histone h2a acetylation GO:0043968 1 0.022
regulation of transcription elongation from rna polymerase ii promoter GO:0034243 15 0.022
organic cyclic compound catabolic process GO:1901361 168 0.022
Yeast
chromatin assembly or disassembly GO:0006333 52 0.022
axonogenesis GO:0007409 290 0.022
regulation of hydrolase activity GO:0051336 97 0.021
positive regulation of protein modification process GO:0031401 58 0.021
small gtpase mediated signal transduction GO:0007264 88 0.021
negative regulation of cellular macromolecule biosynthetic process GO:2000113 267 0.021
dendrite development GO:0016358 204 0.021
gene silencing by rna GO:0031047 57 0.020
ribonucleoside monophosphate metabolic process GO:0009161 51 0.020
Yeast
response to oxygen containing compound GO:1901700 200 0.020
proteolysis GO:0006508 192 0.020
defense response GO:0006952 300 0.020
regulation of rna splicing GO:0043484 69 0.020
purine nucleoside metabolic process GO:0042278 127 0.019
Yeast
cellular macromolecule catabolic process GO:0044265 136 0.019
humoral immune response GO:0006959 117 0.019
negative regulation of gene expression epigenetic GO:0045814 77 0.018
response to lipid GO:0033993 38 0.018
regulation of gene silencing GO:0060968 63 0.018
regulation of cell division GO:0051302 72 0.018
Worm
chromatin silencing GO:0006342 76 0.018
establishment of localization in cell GO:0051649 402 0.018
single organism catabolic process GO:0044712 228 0.017
Yeast
purine nucleoside monophosphate metabolic process GO:0009126 50 0.017
Yeast
dna conformation change GO:0071103 105 0.017
regulation of immune response GO:0050776 118 0.017
nucleotide catabolic process GO:0009166 109 0.017
Yeast
purine nucleoside triphosphate metabolic process GO:0009144 119 0.017
Yeast
ribose phosphate metabolic process GO:0019693 145 0.016
Yeast
regulation of cell morphogenesis GO:0022604 163 0.016
ribonucleotide metabolic process GO:0009259 145 0.016
Yeast
ribonucleoside monophosphate catabolic process GO:0009158 39 0.016
Yeast
regulation of transcription from rna polymerase ii promoter GO:0006357 378 0.016
positive regulation of signaling GO:0023056 243 0.016
muscle organ development GO:0007517 127 0.016
transcription initiation from rna polymerase ii promoter GO:0006367 25 0.016
appendage morphogenesis GO:0035107 397 0.015
response to organic substance GO:0010033 284 0.015
positive regulation of cellular amino acid metabolic process GO:0045764 0 0.015
dna dependent dna replication GO:0006261 17 0.015
purine ribonucleoside metabolic process GO:0046128 127 0.015
Yeast
purine containing compound metabolic process GO:0072521 155 0.015
Yeast
molting cycle process GO:0022404 29 0.015
cellular response to organic substance GO:0071310 132 0.015
cytoskeleton dependent intracellular transport GO:0030705 44 0.015
rna interference GO:0016246 27 0.014
regulation of cell death GO:0010941 173 0.014
reproductive system development GO:0061458 74 0.014
Worm
cell cycle dna replication GO:0044786 23 0.014
localization of cell GO:0051674 257 0.014
sensory organ morphogenesis GO:0090596 260 0.014
morphogenesis of an epithelium GO:0002009 276 0.014
dna biosynthetic process GO:0071897 24 0.014
eye development GO:0001654 323 0.013
posttranscriptional gene silencing GO:0016441 46 0.013
covalent chromatin modification GO:0016569 106 0.013
regulation of catalytic activity GO:0050790 185 0.013
cell cell signaling involved in cell fate commitment GO:0045168 210 0.012
positive regulation of response to stimulus GO:0048584 323 0.012
atp metabolic process GO:0046034 49 0.012
Yeast
purine nucleotide catabolic process GO:0006195 109 0.012
Yeast
nucleobase containing small molecule metabolic process GO:0055086 174 0.012
Yeast
negative regulation of nucleobase containing compound metabolic process GO:0045934 261 0.012
phosphorylation GO:0016310 294 0.012
negative regulation of developmental process GO:0051093 201 0.012
regulation of mrna metabolic process GO:1903311 72 0.012
heart development GO:0007507 82 0.012
chemotaxis GO:0006935 249 0.012
negative regulation of cell communication GO:0010648 223 0.012
regulation of cellular amino acid metabolic process GO:0006521 0 0.012
single organism intracellular transport GO:1902582 207 0.012
camera type eye development GO:0043010 4 0.012
defense response to bacterium GO:0042742 178 0.011
muscle structure development GO:0061061 224 0.011
regulation of mitotic cell cycle GO:0007346 190 0.011
gland development GO:0048732 191 0.011
body morphogenesis GO:0010171 2 0.011
Worm
regulation of neurogenesis GO:0050767 158 0.011
mrna polyadenylation GO:0006378 11 0.011
salivary gland morphogenesis GO:0007435 145 0.011
cellular response to chemical stimulus GO:0070887 199 0.011
cytoplasmic transport GO:0016482 130 0.011
negative regulation of cell cycle process GO:0010948 109 0.011
amine metabolic process GO:0009308 12 0.011
cellular protein complex assembly GO:0043623 71 0.011
stem cell differentiation GO:0048863 117 0.011
mitotic sister chromatid segregation GO:0000070 87 0.011
nucleoside monophosphate catabolic process GO:0009125 39 0.011
Yeast
negative regulation of rna biosynthetic process GO:1902679 240 0.011
response to heat GO:0009408 63 0.011
sex differentiation GO:0007548 81 0.010
Worm
alternative mrna splicing via spliceosome GO:0000380 60 0.010
regulation of gene expression epigenetic GO:0040029 128 0.010
negative regulation of cellular biosynthetic process GO:0031327 277 0.010
oocyte differentiation GO:0009994 145 0.010
positive regulation of intracellular signal transduction GO:1902533 116 0.010
tube development GO:0035295 244 0.010
Zebrafish
positive regulation of protein metabolic process GO:0051247 128 0.010
oocyte development GO:0048599 124 0.010
telomere organization GO:0032200 21 0.010
carbohydrate derivative biosynthetic process GO:1901137 85 0.010

l(2)37Cb disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.020
nervous system disease DOID:863 0 0.011