Drosophila melanogaster

39 known processes

Rpb5 (Dmel_CG11979)

CG11979 gene product from transcript CG11979-RA

(Aliases: RPB5,CG11979,DmRPB5,Dmel\CG11979)

Rpb5 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
embryo development ending in birth or egg hatching GO:0009792 152 0.373
Worm
mrna metabolic process GO:0016071 124 0.283
rna processing GO:0006396 147 0.271
regulation of meiosis GO:0040020 3 0.217
development of primary sexual characteristics GO:0045137 50 0.182
Worm
mrna processing GO:0006397 104 0.145
cell proliferation GO:0008283 299 0.139
rna splicing GO:0008380 83 0.121
regulation of cell cycle process GO:0010564 181 0.112
reproductive structure development GO:0048608 74 0.107
Worm
mitotic g2 dna damage checkpoint GO:0007095 69 0.106
mitotic dna damage checkpoint GO:0044773 74 0.104
regulation of cell cycle GO:0051726 291 0.099
sex differentiation GO:0007548 81 0.098
Worm
macromolecular complex assembly GO:0065003 256 0.095
negative regulation of intrinsic apoptotic signaling pathway GO:2001243 1 0.092
larval development GO:0002164 104 0.092
molting cycle GO:0042303 56 0.091
ribonucleoprotein complex biogenesis GO:0022613 31 0.090
spindle organization GO:0007051 253 0.085
gonad development GO:0008406 50 0.081
Worm
transcription from rna polymerase ii promoter GO:0006366 368 0.079
Human Yeast
ncrna metabolic process GO:0034660 43 0.072
negative regulation of cell cycle phase transition GO:1901988 103 0.068
mrna splicing via spliceosome GO:0000398 73 0.065
reproductive system development GO:0061458 74 0.063
Worm
negative regulation of mitotic cell cycle GO:0045930 109 0.060
rna splicing via transesterification reactions with bulged adenosine as nucleophile GO:0000377 73 0.058
rna splicing via transesterification reactions GO:0000375 73 0.056
cell chemotaxis involved in malpighian tubule morphogenesis GO:0061352 3 0.044
regulation of nuclear division GO:0051783 58 0.044
cell death GO:0008219 279 0.044
positive regulation of macromolecule biosynthetic process GO:0010557 283 0.042
macromolecule catabolic process GO:0009057 161 0.041
regulation of growth GO:0040008 233 0.040
regulation of rac gtpase activity GO:0032314 1 0.039
regulation of cell proliferation GO:0042127 163 0.038
genitalia development GO:0048806 26 0.038
Worm
regulation of cell death GO:0010941 173 0.033
dna integrity checkpoint GO:0031570 81 0.033
gene silencing GO:0016458 138 0.033
negative regulation of gtp catabolic process GO:0033125 1 0.033
intermediate filament cytoskeleton organization GO:0045104 1 0.033
dna methylation on cytosine GO:0032776 1 0.032
left right axis specification GO:0070986 1 0.032
mitotic cell cycle checkpoint GO:0007093 88 0.031
regulation of mitotic cell cycle GO:0007346 190 0.031
regulation of rap gtpase activity GO:0032317 3 0.031
establishment of localization in cell GO:0051649 402 0.030
cellular macromolecular complex assembly GO:0034622 153 0.029
organelle assembly GO:0070925 198 0.029
meiotic nuclear division GO:0007126 151 0.029
phosphorylation GO:0016310 294 0.028
positive regulation of rna biosynthetic process GO:1902680 266 0.028
meiotic cell cycle GO:0051321 171 0.028
negative regulation of developmental pigmentation GO:0048086 1 0.028
death GO:0016265 284 0.027
negative regulation of purine nucleotide catabolic process GO:0033122 1 0.027
positive regulation of biosynthetic process GO:0009891 316 0.027
negative regulation of mitotic anaphase promoting complex activity GO:0060564 2 0.026
formation of a compartment boundary GO:0060288 4 0.025
organelle fission GO:0048285 340 0.025
cell motility GO:0048870 251 0.025
nucleocytoplasmic transport GO:0006913 72 0.025
positive regulation of ubiquitin protein transferase activity GO:0051443 1 0.023
cellular catabolic process GO:0044248 372 0.023
positive regulation of rna metabolic process GO:0051254 271 0.023
protein modification process GO:0036211 438 0.022
regulation of cell diameter GO:0060305 4 0.021
nucleobase containing compound catabolic process GO:0034655 165 0.021
septin cytoskeleton organization GO:0032185 1 0.021
ribonucleoprotein complex assembly GO:0022618 23 0.020
programmed cell death GO:0012501 257 0.020
dorsal vessel heart proper cell fate commitment GO:0035053 2 0.019
regulation of phosphorus metabolic process GO:0051174 210 0.019
meiotic nuclear envelope disassembly GO:0051078 2 0.019
cell division GO:0051301 248 0.019
regulation of cdc42 protein signal transduction GO:0032489 3 0.018
cellular response to dna damage stimulus GO:0006974 223 0.018
negative regulation of nucleoside metabolic process GO:0045978 1 0.018
localization of cell GO:0051674 257 0.018
receptor mediated endocytosis GO:0006898 21 0.018
regulation of mrna splicing via spliceosome GO:0048024 64 0.018
basal protein localization GO:0045175 6 0.018
cell migration GO:0016477 238 0.018
mitotic cell cycle phase transition GO:0044772 138 0.017
chromosome organization GO:0051276 360 0.017
negative regulation of eye photoreceptor cell development GO:0042480 3 0.017
positive regulation of cellular biosynthetic process GO:0031328 316 0.017
cytoplasmic transport GO:0016482 130 0.017
negative regulation of cell cycle GO:0045786 116 0.017
positive regulation of epidermal growth factor activated receptor activity GO:0045741 1 0.017
positive regulation of neuron projection regeneration GO:0070572 3 0.016
ribonucleoprotein complex subunit organization GO:0071826 28 0.016
posttranscriptional regulation of gene expression GO:0010608 145 0.016
positive regulation of golgi to plasma membrane protein transport GO:0042998 2 0.016
regulation of alternative mrna splicing via spliceosome GO:0000381 60 0.016
nuclear division GO:0000280 332 0.016
hematopoietic stem cell differentiation GO:0060218 1 0.016
cellular response to nutrient GO:0031670 1 0.016
establishment or maintenance of polarity of larval imaginal disc epithelium GO:0016336 3 0.015
endocytosis GO:0006897 310 0.015
dendrite regeneration GO:0031104 2 0.015
establishment of protein localization GO:0045184 163 0.015
reactive oxygen species biosynthetic process GO:1903409 0 0.015
intracellular transport GO:0046907 228 0.015
border follicle cell delamination GO:0030709 3 0.015
catabolic process GO:0009056 409 0.015
regulation of meiotic cell cycle GO:0051445 9 0.015
alternative mrna splicing via spliceosome GO:0000380 60 0.015
mitotic nuclear division GO:0007067 213 0.015
regulation of cellular protein metabolic process GO:0032268 243 0.015
positive regulation of macromolecule metabolic process GO:0010604 405 0.014
organic substance catabolic process GO:1901575 308 0.014
regulation of atp metabolic process GO:1903578 6 0.014
negative regulation of gene expression GO:0010629 387 0.014
positive regulation of cell communication GO:0010647 250 0.014
ovulation cycle GO:0042698 1 0.014
positive regulation of nucleic acid templated transcription GO:1903508 266 0.014
negative regulation of nucleotide catabolic process GO:0030812 1 0.014
ncrna processing GO:0034470 30 0.014
base excision repair GO:0006284 2 0.014
mrna catabolic process GO:0006402 33 0.013
intermediate filament based process GO:0045103 1 0.013
phospholipid transport GO:0015914 2 0.013
directional locomotion GO:0033058 1 0.013
positive regulation of protein import into nucleus translocation GO:0033160 2 0.013
growth GO:0040007 359 0.013
secretion GO:0046903 109 0.013
protein complex biogenesis GO:0070271 201 0.012
cellular nitrogen compound catabolic process GO:0044270 165 0.012
regulation of catecholamine metabolic process GO:0042069 3 0.012
regulation of rna splicing GO:0043484 69 0.012
negative regulation of nurse cell apoptotic process GO:0045849 2 0.012
nuclear transport GO:0051169 72 0.012
regulation of homotypic cell cell adhesion GO:0034110 2 0.012
negative regulation of compound eye photoreceptor development GO:0045316 3 0.012
positive regulation of cell maturation GO:1903431 2 0.012
regulation of planar cell polarity pathway involved in axis elongation GO:2000040 2 0.012
regulation of postsynaptic membrane potential GO:0060078 5 0.012
positive regulation of chromatin modification GO:1903310 17 0.012
male germline ring canal formation GO:0030726 3 0.012
regulation of striated muscle contraction GO:0006942 2 0.011
heterocycle catabolic process GO:0046700 166 0.011
positive regulation of nucleobase containing compound metabolic process GO:0045935 332 0.011
protein modification by small protein conjugation or removal GO:0070647 106 0.011
regulation of membrane potential in photoreceptor cell GO:0016057 4 0.011
positive regulation of response to stimulus GO:0048584 323 0.011
phagocytosis GO:0006909 215 0.011
regulation of cell division GO:0051302 72 0.011
nuclear transcribed mrna catabolic process GO:0000956 24 0.011
ovarian follicle cell cell adhesion GO:0007299 4 0.011
positive regulation of atpase activity GO:0032781 3 0.010
organic cyclic compound catabolic process GO:1901361 168 0.010
secretion by cell GO:0032940 101 0.010
attachment of spindle microtubules to kinetochore involved in meiotic chromosome segregation GO:0051316 1 0.010
positive regulation of stem cell maintenance GO:1902459 1 0.010
body morphogenesis GO:0010171 2 0.010
positive regulation of pole plasm oskar mrna localization GO:0045856 2 0.010
regulation of transcription from rna polymerase ii promoter GO:0006357 378 0.010
carboxylic acid metabolic process GO:0019752 92 0.010

Rpb5 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

Disease DO term ID Size Probability Func Analog Org
organ system cancer DOID:0050686 0 0.024
respiratory system cancer DOID:0050615 0 0.024
cancer DOID:162 0 0.024
disease of cellular proliferation DOID:14566 0 0.024
benign neoplasm DOID:0060072 0 0.022
reproductive system disease DOID:15 0 0.019
female reproductive system disease DOID:229 0 0.019
ovarian disease DOID:1100 0 0.019
disease of anatomical entity DOID:7 0 0.019
central nervous system disease DOID:331 0 0.017
neurodegenerative disease DOID:1289 0 0.017
nervous system disease DOID:863 0 0.017
spinocerebellar degeneration DOID:2478 0 0.017
spinocerebellar ataxia DOID:1441 0 0.017
musculoskeletal system disease DOID:17 0 0.016
dysostosis DOID:1934 0 0.016
bone disease DOID:0080001 0 0.016
connective tissue disease DOID:65 0 0.016
bone development disease DOID:0080006 0 0.016
brachydactyly DOID:0050581 0 0.016