Drosophila melanogaster

16 known processes

AR-2 (Dmel_CG10001)

Allatostatin Receptor 2

(Aliases: DAR-2,anon-WO0131005.7,D.AlstR2,CG10001,Dmel\CG10001,DAR,anon-WO0170980.115,anon-WO0170980.116)

AR-2 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
g protein coupled receptor signaling pathway GO:0007186 136 0.178
response to abiotic stimulus GO:0009628 341 0.091
neurological system process GO:0050877 358 0.082
homeostatic process GO:0042592 199 0.070
response to oxygen containing compound GO:1901700 200 0.061
cellular response to chemical stimulus GO:0070887 199 0.053
detection of stimulus GO:0051606 156 0.050
vesicle mediated transport GO:0016192 381 0.048
sensory perception GO:0007600 196 0.043
protein modification process GO:0036211 438 0.041
organonitrogen compound metabolic process GO:1901564 318 0.041
endocytosis GO:0006897 310 0.039
response to ethanol GO:0045471 59 0.039
neuropeptide signaling pathway GO:0007218 45 0.038
cellular protein modification process GO:0006464 438 0.038
morphogenesis of an epithelium GO:0002009 276 0.037
positive regulation of nitrogen compound metabolic process GO:0051173 354 0.036
appendage morphogenesis GO:0035107 397 0.036
negative regulation of response to stimulus GO:0048585 258 0.036
single organism behavior GO:0044708 391 0.035
intracellular signal transduction GO:0035556 300 0.035
camp biosynthetic process GO:0006171 17 0.035
epithelial cell development GO:0002064 274 0.034
response to radiation GO:0009314 155 0.034
multi organism behavior GO:0051705 175 0.034
ion transport GO:0006811 145 0.033
response to organic substance GO:0010033 284 0.033
positive regulation of cell communication GO:0010647 250 0.033
adenylate cyclase modulating g protein coupled receptor signaling pathway GO:0007188 17 0.032
catabolic process GO:0009056 409 0.032
phagocytosis GO:0006909 215 0.032
imaginal disc derived appendage morphogenesis GO:0035114 395 0.031
cellular response to oxygen containing compound GO:1901701 79 0.031
synaptic transmission GO:0007268 288 0.031
cation transport GO:0006812 110 0.031
positive regulation of signaling GO:0023056 243 0.030
single organism biosynthetic process GO:0044711 206 0.030
forebrain development GO:0030900 2 0.029
cellular response to organic substance GO:0071310 132 0.029
positive regulation of cellular biosynthetic process GO:0031328 316 0.029
cell cell junction assembly GO:0007043 38 0.029
multi multicellular organism process GO:0044706 123 0.029
imaginal disc derived appendage development GO:0048737 399 0.029
morphogenesis of embryonic epithelium GO:0016331 94 0.028
post embryonic appendage morphogenesis GO:0035120 385 0.028
open tracheal system development GO:0007424 204 0.028
compound eye development GO:0048749 307 0.028
regulation of anatomical structure size GO:0090066 163 0.028
response to light stimulus GO:0009416 124 0.028
metal ion homeostasis GO:0055065 44 0.028
cyclic nucleotide biosynthetic process GO:0009190 25 0.028
positive regulation of nucleobase containing compound metabolic process GO:0045935 332 0.027
multicellular organismal reproductive behavior GO:0033057 110 0.027
locomotory behavior GO:0007626 176 0.027
appendage development GO:0048736 401 0.027
positive regulation of biosynthetic process GO:0009891 316 0.026
positive regulation of response to stimulus GO:0048584 323 0.026
cell death GO:0008219 279 0.026
cellular macromolecule localization GO:0070727 220 0.026
respiratory system development GO:0060541 213 0.026
adult behavior GO:0030534 137 0.026
circulatory system development GO:0072359 82 0.026
tissue morphogenesis GO:0048729 297 0.026
reproductive behavior GO:0019098 122 0.025
epithelial cell differentiation GO:0030855 322 0.025
organic substance transport GO:0071702 257 0.025
developmental maturation GO:0021700 172 0.025
death GO:0016265 284 0.025
kidney development GO:0001822 3 0.024
g protein coupled receptor signaling pathway coupled to cyclic nucleotide second messenger GO:0007187 17 0.024
negative regulation of cell communication GO:0010648 223 0.024
anatomical structure homeostasis GO:0060249 97 0.024
regulation of multicellular organismal development GO:2000026 414 0.024
programmed cell death GO:0012501 257 0.024
regulation of transport GO:0051049 181 0.024
transmembrane transport GO:0055085 139 0.024
detection of abiotic stimulus GO:0009582 66 0.024
columnar cuboidal epithelial cell development GO:0002066 249 0.024
wing disc morphogenesis GO:0007472 344 0.023
metal ion transport GO:0030001 74 0.023
circadian rhythm GO:0007623 105 0.023
regulation of response to stress GO:0080134 200 0.023
phosphorylation GO:0016310 294 0.023
organelle fission GO:0048285 340 0.023
organic substance catabolic process GO:1901575 308 0.022
detection of external stimulus GO:0009581 66 0.022
regulation of cellular amine metabolic process GO:0033238 3 0.022
negative regulation of signaling GO:0023057 219 0.022
organophosphate metabolic process GO:0019637 195 0.022
inter male aggressive behavior GO:0002121 60 0.022
ion transmembrane transport GO:0034220 122 0.022
protein localization GO:0008104 284 0.022
regulation of phosphate metabolic process GO:0019220 210 0.022
negative regulation of macromolecule biosynthetic process GO:0010558 270 0.022
negative regulation of gene expression GO:0010629 387 0.021
localization of cell GO:0051674 257 0.021
ribonucleotide metabolic process GO:0009259 145 0.021
negative regulation of cellular metabolic process GO:0031324 382 0.021
cellular response to carbohydrate stimulus GO:0071322 4 0.021
actin filament based process GO:0030029 220 0.021
positive regulation of cell migration GO:0030335 2 0.021
detection of light stimulus GO:0009583 58 0.021
gland morphogenesis GO:0022612 145 0.020
regulation of intracellular signal transduction GO:1902531 236 0.020
nuclear division GO:0000280 332 0.020
regulation of cell proliferation GO:0042127 163 0.020
establishment of protein localization GO:0045184 163 0.020
sensory perception of chemical stimulus GO:0007606 116 0.020
regulation of molecular function GO:0065009 217 0.020
negative regulation of cellular biosynthetic process GO:0031327 277 0.020
salivary gland morphogenesis GO:0007435 145 0.020
amine metabolic process GO:0009308 12 0.020
cellular response to endogenous stimulus GO:0071495 80 0.019
developmental programmed cell death GO:0010623 138 0.019
regulation of localization GO:0032879 275 0.019
small molecule metabolic process GO:0044281 305 0.019
cellular amine metabolic process GO:0044106 12 0.019
regulation of behavior GO:0050795 75 0.019
cell cell signaling involved in cell fate commitment GO:0045168 210 0.019
establishment of localization in cell GO:0051649 402 0.019
cardiovascular system development GO:0072358 82 0.019
actin cytoskeleton organization GO:0030036 206 0.019
chemical homeostasis GO:0048878 92 0.019
cyclic purine nucleotide metabolic process GO:0052652 25 0.019
negative regulation of nucleobase containing compound metabolic process GO:0045934 261 0.019
columnar cuboidal epithelial cell differentiation GO:0002065 256 0.019
response to extracellular stimulus GO:0009991 116 0.019
regulation of synaptic transmission GO:0050804 69 0.019
negative regulation of multicellular organismal process GO:0051241 142 0.019
embryonic morphogenesis GO:0048598 206 0.018
negative regulation of rna biosynthetic process GO:1902679 240 0.018
single organism catabolic process GO:0044712 228 0.018
regulation of cyclic nucleotide metabolic process GO:0030799 13 0.018
regionalization GO:0003002 416 0.018
response to endogenous stimulus GO:0009719 119 0.018
regulation of catalytic activity GO:0050790 185 0.018
response to lipopolysaccharide GO:0032496 4 0.018
imaginal disc derived wing morphogenesis GO:0007476 337 0.018
establishment of tissue polarity GO:0007164 87 0.018
multicellular organismal homeostasis GO:0048871 41 0.018
purine containing compound biosynthetic process GO:0072522 30 0.018
negative regulation of biosynthetic process GO:0009890 277 0.018
sensory perception of pain GO:0019233 4 0.018
telencephalon development GO:0021537 2 0.017
negative regulation of nucleic acid templated transcription GO:1903507 240 0.017
connective tissue development GO:0061448 3 0.017
negative regulation of rna metabolic process GO:0051253 251 0.017
cellular metal ion homeostasis GO:0006875 31 0.017
negative regulation of cellular macromolecule biosynthetic process GO:2000113 267 0.017
regulation of tube size GO:0035150 46 0.017
regulation of synapse structure and activity GO:0050803 128 0.017
dendrite development GO:0016358 204 0.017
body morphogenesis GO:0010171 2 0.017
phototransduction GO:0007602 52 0.017
cellular catabolic process GO:0044248 372 0.017
cell adhesion involved in heart morphogenesis GO:0061343 12 0.017
eye morphogenesis GO:0048592 260 0.017
protein transport GO:0015031 155 0.017
segmentation GO:0035282 207 0.017
proteolysis GO:0006508 192 0.017
tripartite regional subdivision GO:0007351 103 0.017
negative regulation of nitrogen compound metabolic process GO:0051172 265 0.017
regulation of cellular ketone metabolic process GO:0010565 3 0.017
tissue homeostasis GO:0001894 36 0.017
cation homeostasis GO:0055080 51 0.016
cell proliferation GO:0008283 299 0.016
regulation of cellular component biogenesis GO:0044087 201 0.016
cellular response to hormone stimulus GO:0032870 44 0.016
gene silencing GO:0016458 138 0.016
cell adhesion GO:0007155 136 0.016
multi organism reproductive behavior GO:0044705 121 0.016
protein hydroxylation GO:0018126 1 0.016
response to organic cyclic compound GO:0014070 89 0.016
salivary gland development GO:0007431 162 0.016
cellular response to dna damage stimulus GO:0006974 223 0.016
carbohydrate derivative metabolic process GO:1901135 217 0.016
gland development GO:0048732 191 0.016
nucleotide biosynthetic process GO:0009165 34 0.016
nucleobase containing small molecule metabolic process GO:0055086 174 0.016
positive regulation of cell motility GO:2000147 3 0.016
regulation of immune system process GO:0002682 176 0.016
regulation of cellular localization GO:0060341 136 0.016
positive regulation of intracellular signal transduction GO:1902533 116 0.016
stem cell differentiation GO:0048863 117 0.016
chromosome organization GO:0051276 360 0.016
chemotaxis GO:0006935 249 0.016
protein phosphorylation GO:0006468 169 0.015
histolysis GO:0007559 102 0.015
cellular amino acid metabolic process GO:0006520 61 0.015
rhythmic process GO:0048511 106 0.015
detection of chemical stimulus GO:0009593 93 0.015
embryonic axis specification GO:0000578 107 0.015
camera type eye development GO:0043010 4 0.015
meiosis i GO:0007127 59 0.015
behavioral response to pain GO:0048266 3 0.015
negative regulation of transcription dna templated GO:0045892 237 0.015
autophagic cell death GO:0048102 83 0.015
leg disc development GO:0035218 92 0.015
positive regulation of gene expression GO:0010628 290 0.015
regulation of phosphorus metabolic process GO:0051174 210 0.015
transcription from rna polymerase ii promoter GO:0006366 368 0.015
response to pain GO:0048265 3 0.015
cellular protein localization GO:0034613 160 0.015
positive regulation of phosphate metabolic process GO:0045937 139 0.015
cellular homeostasis GO:0019725 80 0.015
purine nucleotide metabolic process GO:0006163 146 0.015
regulation of cell death GO:0010941 173 0.015
response to external biotic stimulus GO:0043207 293 0.015
lateral inhibition GO:0046331 206 0.015
cell maturation GO:0048469 144 0.015
carboxylic acid metabolic process GO:0019752 92 0.015
hindbrain development GO:0030902 2 0.015
sensory perception of smell GO:0007608 80 0.014
photoreceptor cell development GO:0042461 96 0.014
purine ribonucleotide metabolic process GO:0009150 145 0.014
regulation of cell shape GO:0008360 113 0.014
salt aversion GO:0035199 3 0.014
protein complex biogenesis GO:0070271 201 0.014
ovarian follicle cell development GO:0030707 248 0.014
establishment of planar polarity GO:0001736 87 0.014
regulation of tube size open tracheal system GO:0035151 43 0.014
learning or memory GO:0007611 141 0.014
purine ribonucleotide biosynthetic process GO:0009152 28 0.014
cognition GO:0050890 141 0.014
cell migration GO:0016477 238 0.014
ion homeostasis GO:0050801 55 0.014
response to oxidative stress GO:0006979 86 0.014
septate junction assembly GO:0019991 26 0.014
positive regulation of nucleic acid templated transcription GO:1903508 266 0.014
mitotic spindle organization GO:0007052 220 0.014
carbohydrate derivative biosynthetic process GO:1901137 85 0.014
regulation of cellular amino acid metabolic process GO:0006521 0 0.014
taxis GO:0042330 304 0.014
imaginal disc pattern formation GO:0007447 91 0.014
positive regulation of signal transduction GO:0009967 223 0.014
macromolecular complex assembly GO:0065003 256 0.014
positive regulation of macromolecule metabolic process GO:0010604 405 0.014
response to nitrogen compound GO:1901698 90 0.014
positive regulation of molecular function GO:0044093 136 0.014
embryonic pattern specification GO:0009880 174 0.013
endomembrane system organization GO:0010256 119 0.013
signal transduction by phosphorylation GO:0023014 107 0.013
tissue death GO:0016271 102 0.013
synapse organization GO:0050808 196 0.013
positive regulation of catalytic activity GO:0043085 118 0.013
positive regulation of phosphorus metabolic process GO:0010562 139 0.013
positive regulation of lipid storage GO:0010884 4 0.013
ribose phosphate metabolic process GO:0019693 145 0.013
regulation of epithelial cell proliferation GO:0050678 4 0.013
inorganic cation transmembrane transport GO:0098662 61 0.013
mesenchymal cell differentiation GO:0048762 1 0.013
embryo development ending in birth or egg hatching GO:0009792 152 0.013
nucleoside phosphate biosynthetic process GO:1901293 34 0.013
nucleotide metabolic process GO:0009117 161 0.013
response to biotic stimulus GO:0009607 294 0.013
biological adhesion GO:0022610 138 0.013
meiotic cell cycle GO:0051321 171 0.013
positive regulation of macromolecule biosynthetic process GO:0010557 283 0.013
aging GO:0007568 143 0.013
heart development GO:0007507 82 0.013
regulation of anatomical structure morphogenesis GO:0022603 242 0.013
regulation of membrane potential GO:0042391 35 0.013
response to nutrient levels GO:0031667 114 0.013
regulation of protein metabolic process GO:0051246 256 0.013
embryonic development via the syncytial blastoderm GO:0001700 148 0.013
regulation of programmed cell death GO:0043067 152 0.013
regulation of cell cycle process GO:0010564 181 0.013
central nervous system development GO:0007417 201 0.013
axis specification GO:0009798 167 0.013
apoptotic process GO:0006915 159 0.013
immune system process GO:0002376 347 0.013
cholesterol homeostasis GO:0042632 3 0.013
protein complex assembly GO:0006461 200 0.013
anterior posterior axis specification GO:0009948 109 0.013
male courtship behavior GO:0008049 63 0.013
retina development in camera type eye GO:0060041 4 0.013
limb development GO:0060173 1 0.012
oligosaccharide transport GO:0015772 2 0.012
anterior posterior pattern specification GO:0009952 136 0.012
exocrine system development GO:0035272 162 0.012
cell junction assembly GO:0034329 42 0.012
organonitrogen compound biosynthetic process GO:1901566 117 0.012
feeding behavior GO:0007631 50 0.012
morphogenesis of a polarized epithelium GO:0001738 93 0.012
cellular response to biotic stimulus GO:0071216 4 0.012
l amino acid import GO:0043092 2 0.012
sensory organ morphogenesis GO:0090596 260 0.012
cellular ion homeostasis GO:0006873 39 0.012
camp metabolic process GO:0046058 19 0.012
dna metabolic process GO:0006259 227 0.012
cell junction organization GO:0034330 57 0.012
cell cell junction organization GO:0045216 55 0.012
response to salt stress GO:0009651 11 0.012
rna localization GO:0006403 115 0.012
cellular divalent inorganic cation homeostasis GO:0072503 23 0.012
pigmentation GO:0043473 75 0.012
intracellular transport GO:0046907 228 0.012
cellular response to molecule of bacterial origin GO:0071219 3 0.012
sodium dependent phosphate transport GO:0044341 2 0.012
regulation of phosphorylation GO:0042325 147 0.012
dorsal ventral pattern formation GO:0009953 133 0.012
sensory perception of mechanical stimulus GO:0050954 72 0.012
lipid metabolic process GO:0006629 121 0.012
hormone catabolic process GO:0042447 3 0.012
mapk cascade GO:0000165 107 0.012
response to osmotic stress GO:0006970 14 0.012
small gtpase mediated signal transduction GO:0007264 88 0.012
regulation of nucleotide biosynthetic process GO:0030808 14 0.012
drinking behavior GO:0042756 2 0.012
positive regulation of rna biosynthetic process GO:1902680 266 0.012
response to high light intensity GO:0009644 1 0.012
hindgut development GO:0061525 58 0.012
l glutamate import GO:0051938 1 0.012
imaginal disc derived leg morphogenesis GO:0007480 80 0.012
negative regulation of cellular component organization GO:0051129 108 0.012
photoreceptor cell differentiation GO:0046530 170 0.012
regulation of cell morphogenesis GO:0022604 163 0.012
eggshell formation GO:0030703 105 0.011
limb morphogenesis GO:0035108 1 0.011
single organism intracellular transport GO:1902582 207 0.011
cellular ketone metabolic process GO:0042180 24 0.011
purine containing compound metabolic process GO:0072521 155 0.011
sterol homeostasis GO:0055092 4 0.011
ras protein signal transduction GO:0007265 88 0.011
determination of adult lifespan GO:0008340 137 0.011
positive regulation of multicellular organismal process GO:0051240 143 0.011
chromatin organization GO:0006325 207 0.011
cellular response to hexose stimulus GO:0071331 1 0.011
response to organophosphorus GO:0046683 2 0.011
positive regulation of cellular amino acid metabolic process GO:0045764 0 0.011
cellular chemical homeostasis GO:0055082 40 0.011
gastrulation involving germ band extension GO:0010004 36 0.011
single organism cellular localization GO:1902580 180 0.011
nucleoside phosphate metabolic process GO:0006753 162 0.011
regulation of cell cycle GO:0051726 291 0.011
oxoacid metabolic process GO:0043436 103 0.011
divalent inorganic cation homeostasis GO:0072507 29 0.011
anterior posterior axis specification embryo GO:0008595 103 0.011
immune response activating signal transduction GO:0002757 2 0.011
leg disc morphogenesis GO:0007478 80 0.011
regulation of i kappab kinase nf kappab signaling GO:0043122 2 0.011
negative regulation of developmental process GO:0051093 201 0.011
cellular response to nitrogen compound GO:1901699 51 0.011
positive regulation of phosphorylation GO:0042327 87 0.011
rna processing GO:0006396 147 0.011
multicellular organismal aging GO:0010259 140 0.011
response to glucose GO:0009749 2 0.011
negative regulation of signal transduction GO:0009968 206 0.011
regulation of mapk cascade GO:0043408 92 0.011
oocyte construction GO:0007308 112 0.011
axon guidance GO:0007411 233 0.011
positive regulation of cellular component biogenesis GO:0044089 80 0.011
eye development GO:0001654 323 0.011
cellular response to abiotic stimulus GO:0071214 58 0.011
water homeostasis GO:0030104 3 0.011
sensory perception of salty taste GO:0050914 3 0.011
response to monosaccharide GO:0034284 4 0.011
response to hormone GO:0009725 45 0.011
ribonucleotide biosynthetic process GO:0009260 28 0.011
response to hypoxia GO:0001666 53 0.011
regulation of cell differentiation GO:0045595 302 0.011
cellular calcium ion homeostasis GO:0006874 21 0.011
cell division GO:0051301 248 0.011
regulation of apoptotic process GO:0042981 130 0.011
androgen metabolic process GO:0008209 1 0.011
regulation of response to external stimulus GO:0032101 115 0.011
developmental pigmentation GO:0048066 68 0.011
regulation of embryonic development GO:0045995 68 0.011
salivary gland histolysis GO:0035070 88 0.011
blastoderm segmentation GO:0007350 159 0.011
cell cycle phase transition GO:0044770 140 0.011
behavioral response to ethanol GO:0048149 49 0.011
response to oxygen levels GO:0070482 59 0.011
ameboidal type cell migration GO:0001667 151 0.011
peptide metabolic process GO:0006518 80 0.011
response to other organism GO:0051707 293 0.011
mitotic cell cycle phase transition GO:0044772 138 0.011
spermatogenesis GO:0007283 200 0.011
ethanolamine containing compound metabolic process GO:0042439 4 0.010
chorion containing eggshell formation GO:0007304 105 0.010
negative regulation of mitotic cell cycle phase transition GO:1901991 103 0.010
response to bacterium GO:0009617 198 0.010
actin filament organization GO:0007015 126 0.010
intracellular protein transport GO:0006886 104 0.010
membrane organization GO:0061024 112 0.010
molting cycle chitin based cuticle GO:0007591 56 0.010
jak stat cascade GO:0007259 49 0.010
acylglycerol biosynthetic process GO:0046463 2 0.010
male mating behavior GO:0060179 70 0.010
mesenchymal cell development GO:0014031 1 0.010
embryonic hindgut morphogenesis GO:0048619 48 0.010
aggressive behavior GO:0002118 63 0.010
response to organonitrogen compound GO:0010243 75 0.010
neuron neuron synaptic transmission GO:0007270 14 0.010
regulation of cellular response to stress GO:0080135 89 0.010
establishment or maintenance of cell polarity GO:0007163 167 0.010
negative regulation of cell death GO:0060548 81 0.010
positive regulation of cellular component organization GO:0051130 156 0.010
cellular cation homeostasis GO:0030003 38 0.010
developmental growth GO:0048589 280 0.010
dendrite morphogenesis GO:0048813 199 0.010
regulation of transcription from rna polymerase ii promoter GO:0006357 378 0.010
epithelial cell migration GO:0010631 148 0.010

AR-2 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.070
renal tubular transport disease DOID:447 0 0.034
kidney disease DOID:557 0 0.034
urinary system disease DOID:18 0 0.034
musculoskeletal system disease DOID:17 0 0.021
disease of metabolism DOID:0014667 0 0.017
bone disease DOID:0080001 0 0.017
connective tissue disease DOID:65 0 0.017
nervous system disease DOID:863 0 0.016
inherited metabolic disorder DOID:655 0 0.012
acquired metabolic disease DOID:0060158 0 0.012
central nervous system disease DOID:331 0 0.011