Drosophila melanogaster

66 known processes

fl(2)d (Dmel_CG6315)

female lethal d

(Aliases: Dmel\CG6315,v(2)k16105,CG6315)

fl(2)d biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
eye development GO:0001654 323 0.986
wing disc morphogenesis GO:0007472 344 0.901
transcription from rna polymerase ii promoter GO:0006366 368 0.852
sensory organ morphogenesis GO:0090596 260 0.847
compound eye morphogenesis GO:0001745 249 0.749
eye morphogenesis GO:0048592 260 0.719
appendage development GO:0048736 401 0.718
cellular response to chemical stimulus GO:0070887 199 0.682
imaginal disc derived appendage development GO:0048737 399 0.648
positive regulation of biosynthetic process GO:0009891 316 0.576
negative regulation of cell communication GO:0010648 223 0.546
taxis GO:0042330 304 0.494
negative regulation of signaling GO:0023057 219 0.477
compound eye development GO:0048749 307 0.469
g2 dna damage checkpoint GO:0031572 69 0.419
positive regulation of rna biosynthetic process GO:1902680 266 0.416
regulation of gene expression epigenetic GO:0040029 128 0.382
neurological system process GO:0050877 358 0.362
epidermis development GO:0008544 65 0.332
intracellular signal transduction GO:0035556 300 0.303
photoreceptor cell differentiation GO:0046530 170 0.297
mitotic dna integrity checkpoint GO:0044774 75 0.288
regulation of organelle organization GO:0033043 196 0.286
regulation of transcription from rna polymerase ii promoter GO:0006357 378 0.279
mitotic g2 m transition checkpoint GO:0044818 70 0.278
negative regulation of macromolecule biosynthetic process GO:0010558 270 0.266
cellular response to dna damage stimulus GO:0006974 223 0.263
negative regulation of response to stimulus GO:0048585 258 0.262
proteolysis GO:0006508 192 0.252
cell division GO:0051301 248 0.252
appendage morphogenesis GO:0035107 397 0.249
positive regulation of nitrogen compound metabolic process GO:0051173 354 0.227
axon development GO:0061564 297 0.224
imaginal disc derived wing morphogenesis GO:0007476 337 0.216
establishment of localization in cell GO:0051649 402 0.213
dna damage checkpoint GO:0000077 78 0.210
positive regulation of rna metabolic process GO:0051254 271 0.210
phosphorylation GO:0016310 294 0.194
axon guidance GO:0007411 233 0.190
cellular protein modification process GO:0006464 438 0.187
regulation of phosphate metabolic process GO:0019220 210 0.187
positive regulation of macromolecule metabolic process GO:0010604 405 0.183
cell migration GO:0016477 238 0.183
signal transduction by phosphorylation GO:0023014 107 0.182
mitotic dna damage checkpoint GO:0044773 74 0.182
eye photoreceptor cell development GO:0042462 81 0.170
protein modification process GO:0036211 438 0.166
tube development GO:0035295 244 0.162
imaginal disc derived appendage morphogenesis GO:0035114 395 0.162
response to organic substance GO:0010033 284 0.154
cell motility GO:0048870 251 0.153
regulation of mitotic cell cycle GO:0007346 190 0.147
regulation of phosphorylation GO:0042325 147 0.144
growth GO:0040007 359 0.144
negative regulation of nucleic acid templated transcription GO:1903507 240 0.142
positive regulation of multicellular organismal process GO:0051240 143 0.136
positive regulation of transcription from rna polymerase ii promoter GO:0045944 204 0.134
post embryonic appendage morphogenesis GO:0035120 385 0.132
negative regulation of biosynthetic process GO:0009890 277 0.131
regulation of mapk cascade GO:0043408 92 0.131
immune system development GO:0002520 57 0.130
single organism cellular localization GO:1902580 180 0.128
regulation of localization GO:0032879 275 0.127
negative regulation of gene expression GO:0010629 387 0.126
regulation of cell proliferation GO:0042127 163 0.126
regulation of intracellular signal transduction GO:1902531 236 0.126
macromolecular complex assembly GO:0065003 256 0.123
regulation of multicellular organismal development GO:2000026 414 0.121
ras protein signal transduction GO:0007265 88 0.120
gene silencing by mirna GO:0035195 22 0.119
positive regulation of phosphorus metabolic process GO:0010562 139 0.117
compound eye photoreceptor development GO:0042051 78 0.112
eye photoreceptor cell differentiation GO:0001754 145 0.112
regulation of transport GO:0051049 181 0.111
tube morphogenesis GO:0035239 191 0.111
cellular response to oxygen containing compound GO:1901701 79 0.110
mitotic cell cycle checkpoint GO:0007093 88 0.110
negative regulation of cell cycle process GO:0010948 109 0.110
positive regulation of molecular function GO:0044093 136 0.109
regulation of anatomical structure morphogenesis GO:0022603 242 0.109
neuron projection guidance GO:0097485 241 0.101
body morphogenesis GO:0010171 2 0.099
positive regulation of response to stimulus GO:0048584 323 0.097
positive regulation of nucleobase containing compound metabolic process GO:0045935 332 0.097
regulation of cellular protein metabolic process GO:0032268 243 0.097
gene silencing GO:0016458 138 0.094
regulation of protein metabolic process GO:0051246 256 0.092
dna integrity checkpoint GO:0031570 81 0.090
positive regulation of transcription dna templated GO:0045893 266 0.087
protein targeting GO:0006605 64 0.087
apoptotic process GO:0006915 159 0.086
regulation of cell differentiation GO:0045595 302 0.083
cell cycle checkpoint GO:0000075 95 0.083
negative regulation of cellular metabolic process GO:0031324 382 0.081
regulation of cell cycle process GO:0010564 181 0.080
endocytosis GO:0006897 310 0.080
organelle fission GO:0048285 340 0.078
single organism behavior GO:0044708 391 0.077
positive regulation of gene expression GO:0010628 290 0.076
positive regulation of intracellular signal transduction GO:1902533 116 0.076
negative regulation of transcription from rna polymerase ii promoter GO:0000122 119 0.076
regulation of cellular component size GO:0032535 98 0.075
photoreceptor cell development GO:0042461 96 0.075
regulation of erk1 and erk2 cascade GO:0070372 39 0.071
cellular macromolecule catabolic process GO:0044265 136 0.070
nuclear division GO:0000280 332 0.070
negative regulation of signal transduction GO:0009968 206 0.068
negative regulation of mitotic cell cycle phase transition GO:1901991 103 0.068
cell proliferation GO:0008283 299 0.066
regulation of cell development GO:0060284 215 0.065
nuclear transport GO:0051169 72 0.065
vesicle mediated transport GO:0016192 381 0.065
negative regulation of nitrogen compound metabolic process GO:0051172 265 0.064
regulation of meiosis GO:0040020 3 0.064
muscle organ development GO:0007517 127 0.063
negative regulation of cell cycle GO:0045786 116 0.063
small gtpase mediated signal transduction GO:0007264 88 0.062
positive regulation of phosphorylation GO:0042327 87 0.062
cell cell signaling involved in cell fate commitment GO:0045168 210 0.062
cell death GO:0008219 279 0.061
positive regulation of mapk cascade GO:0043410 63 0.061
regulation of cellular response to stress GO:0080135 89 0.060
digestive tract morphogenesis GO:0048546 127 0.060
positive regulation of cellular protein metabolic process GO:0032270 118 0.060
cell fate specification GO:0001708 71 0.059
positive regulation of nucleic acid templated transcription GO:1903508 266 0.058
negative regulation of cellular component organization GO:0051129 108 0.057
proteolysis involved in cellular protein catabolic process GO:0051603 83 0.057
mapk cascade GO:0000165 107 0.057
cellular protein catabolic process GO:0044257 83 0.057
positive regulation of developmental process GO:0051094 143 0.057
embryo development ending in birth or egg hatching GO:0009792 152 0.056
intracellular protein transport GO:0006886 104 0.056
cell cycle phase transition GO:0044770 140 0.056
lateral inhibition GO:0046331 206 0.055
positive regulation of signaling GO:0023056 243 0.055
protein transport GO:0015031 155 0.055
positive regulation of phosphate metabolic process GO:0045937 139 0.054
chromatin modification GO:0016568 147 0.054
regulation of protein localization GO:0032880 76 0.053
negative regulation of rna biosynthetic process GO:1902679 240 0.052
axonogenesis GO:0007409 290 0.050
organonitrogen compound metabolic process GO:1901564 318 0.050
proteasomal protein catabolic process GO:0010498 59 0.050
skin development GO:0043588 65 0.050
response to endogenous stimulus GO:0009719 119 0.049
regulation of response to stress GO:0080134 200 0.048
regulation of cell cycle phase transition GO:1901987 130 0.048
histone modification GO:0016570 106 0.048
negative regulation of cell proliferation GO:0008285 69 0.047
modification dependent macromolecule catabolic process GO:0043632 79 0.046
erk1 and erk2 cascade GO:0070371 39 0.045
brain development GO:0007420 120 0.044
ubiquitin dependent protein catabolic process GO:0006511 78 0.044
regulation of cellular catabolic process GO:0031329 157 0.044
regulation of phosphorus metabolic process GO:0051174 210 0.043
regulation of molecular function GO:0065009 217 0.043
regulation of gene silencing GO:0060968 63 0.042
organic acid metabolic process GO:0006082 103 0.041
mitochondrial membrane organization GO:0007006 3 0.041
covalent chromatin modification GO:0016569 106 0.041
response to radiation GO:0009314 155 0.039
regulation of rna splicing GO:0043484 69 0.039
response to nutrient levels GO:0031667 114 0.039
digestive system development GO:0055123 149 0.039
negative regulation of multicellular organismal process GO:0051241 142 0.039
response to extracellular stimulus GO:0009991 116 0.039
negative regulation of cell differentiation GO:0045596 143 0.038
posttranscriptional gene silencing GO:0016441 46 0.038
negative regulation of developmental process GO:0051093 201 0.037
regulation of anatomical structure size GO:0090066 163 0.037
negative regulation of rna metabolic process GO:0051253 251 0.036
positive regulation of macromolecule biosynthetic process GO:0010557 283 0.036
positive regulation of erk1 and erk2 cascade GO:0070374 36 0.036
regulation of cellular localization GO:0060341 136 0.035
cellular response to peptide GO:1901653 28 0.035
carboxylic acid metabolic process GO:0019752 92 0.035
epithelium migration GO:0090132 148 0.035
developmental growth GO:0048589 280 0.035
programmed cell death GO:0012501 257 0.035
negative regulation of cell cycle phase transition GO:1901988 103 0.035
biological adhesion GO:0022610 138 0.034
regulation of nervous system development GO:0051960 248 0.034
epidermal cell differentiation GO:0009913 51 0.034
regulation of neuron differentiation GO:0045664 103 0.034
single organism intracellular transport GO:1902582 207 0.034
regulation of developmental growth GO:0048638 174 0.034
positive regulation of transport GO:0051050 92 0.034
regulation of cell cycle GO:0051726 291 0.034
compound eye photoreceptor cell differentiation GO:0001751 140 0.033
regulation of protein modification process GO:0031399 112 0.033
macromolecule catabolic process GO:0009057 161 0.033
positive regulation of protein metabolic process GO:0051247 128 0.033
death GO:0016265 284 0.033
regulation of programmed cell death GO:0043067 152 0.032
negative regulation of intracellular signal transduction GO:1902532 57 0.032
response to oxidative stress GO:0006979 86 0.032
response to abiotic stimulus GO:0009628 341 0.032
establishment of protein localization to organelle GO:0072594 62 0.031
meiotic cell cycle process GO:1903046 132 0.031
formation of a compartment boundary GO:0060288 4 0.031
protein catabolic process GO:0030163 101 0.031
protein targeting to nucleus GO:0044744 51 0.030
regulation of small gtpase mediated signal transduction GO:0051056 93 0.030
localization of cell GO:0051674 257 0.030
cellular response to nitrogen compound GO:1901699 51 0.030
cell cycle dna replication GO:0044786 23 0.030
regulation of intracellular transport GO:0032386 64 0.030
regulation of phosphatase activity GO:0010921 3 0.029
response to organic cyclic compound GO:0014070 89 0.029
negative regulation of mitotic cell cycle GO:0045930 109 0.029
regulation of neurogenesis GO:0050767 158 0.029
chromatin organization GO:0006325 207 0.029
positive regulation of catalytic activity GO:0043085 118 0.028
positive regulation of signal transduction GO:0009967 223 0.028
secondary metabolic process GO:0019748 75 0.027
immune response regulating signaling pathway GO:0002764 2 0.027
digestive tract development GO:0048565 149 0.027
regulation of cell division GO:0051302 72 0.027
positive regulation of developmental growth GO:0048639 62 0.026
negative regulation of cellular macromolecule biosynthetic process GO:2000113 267 0.026
positive regulation of cell communication GO:0010647 250 0.026
regulation of vesicle mediated transport GO:0060627 59 0.026
cellular response to organic cyclic compound GO:0071407 32 0.025
regulation of growth GO:0040008 233 0.025
hemopoiesis GO:0030097 46 0.025
embryonic morphogenesis GO:0048598 206 0.025
gastrulation involving germ band extension GO:0010004 36 0.024
cellular amino acid metabolic process GO:0006520 61 0.024
regulation of striated muscle contraction GO:0006942 2 0.024
epithelial cell migration GO:0010631 148 0.024
cellular protein localization GO:0034613 160 0.024
larval development GO:0002164 104 0.023
stem cell maintenance GO:0019827 67 0.023
adult behavior GO:0030534 137 0.023
regulation of cellular amine metabolic process GO:0033238 3 0.023
mitotic g2 dna damage checkpoint GO:0007095 69 0.023
positive regulation of protein modification process GO:0031401 58 0.022
mitotic spindle organization GO:0007052 220 0.022
cell adhesion GO:0007155 136 0.021
stem cell differentiation GO:0048863 117 0.021
protein localization to organelle GO:0033365 82 0.021
organic substance transport GO:0071702 257 0.021
cellular response to endogenous stimulus GO:0071495 80 0.021
cellular response to hormone stimulus GO:0032870 44 0.020
response to oxygen containing compound GO:1901700 200 0.020
regulation of hemocyte proliferation GO:0035206 37 0.020
regulation of protein catabolic process GO:0042176 55 0.020
regulation of cellular component movement GO:0051270 42 0.020
single organism biosynthetic process GO:0044711 206 0.019
morphogenesis of a branching structure GO:0001763 45 0.018
brain morphogenesis GO:0048854 16 0.018
ameboidal type cell migration GO:0001667 151 0.018
nucleoside triphosphate catabolic process GO:0009143 108 0.018
meiotic cell cycle GO:0051321 171 0.018
immune system process GO:0002376 347 0.018
camera type eye development GO:0043010 4 0.018
regulation of cellular ketone metabolic process GO:0010565 3 0.018
regulation of cell adhesion GO:0030155 27 0.018
spindle organization GO:0007051 253 0.018
locomotory behavior GO:0007626 176 0.017
chromatin silencing GO:0006342 76 0.017
cellular homeostasis GO:0019725 80 0.017
cellular amine metabolic process GO:0044106 12 0.017
positive regulation of hydrolase activity GO:0051345 78 0.017
amine metabolic process GO:0009308 12 0.017
cellular macromolecular complex assembly GO:0034622 153 0.017
branching morphogenesis of an epithelial tube GO:0048754 45 0.017
diterpenoid biosynthetic process GO:0016102 1 0.017
mitotic nuclear division GO:0007067 213 0.017
cellular ketone metabolic process GO:0042180 24 0.016
negative regulation of nucleobase containing compound metabolic process GO:0045934 261 0.016
regulation of proteolysis involved in cellular protein catabolic process GO:1903050 44 0.016
rna processing GO:0006396 147 0.016
protein import into nucleus GO:0006606 51 0.016
positive regulation of cellular component organization GO:0051130 156 0.016
regeneration GO:0031099 16 0.016
regulation of cellular amino acid metabolic process GO:0006521 0 0.016
rna transport GO:0050658 46 0.015
rna splicing via transesterification reactions with bulged adenosine as nucleophile GO:0000377 73 0.015
actin filament organization GO:0007015 126 0.015
regulation of notch signaling pathway GO:0008593 100 0.015
regulation of stress activated protein kinase signaling cascade GO:0070302 42 0.015
gonad development GO:0008406 50 0.015
rhabdomere development GO:0042052 38 0.014
regulation of cell shape GO:0008360 113 0.014
gland development GO:0048732 191 0.014
aging GO:0007568 143 0.014
regulation of catalytic activity GO:0050790 185 0.014
sister chromatid segregation GO:0000819 92 0.014
cellular catabolic process GO:0044248 372 0.014
intracellular transport GO:0046907 228 0.013
regulation of cell death GO:0010941 173 0.013
negative regulation of transcription dna templated GO:0045892 237 0.013
negative regulation of phosphate metabolic process GO:0045936 45 0.013
positive regulation of organelle organization GO:0010638 65 0.013
memory GO:0007613 94 0.013
protein modification by small protein conjugation or removal GO:0070647 106 0.013
modification dependent protein catabolic process GO:0019941 78 0.013
axon regeneration GO:0031103 8 0.013
neuron fate commitment GO:0048663 50 0.013
stem cell development GO:0048864 79 0.012
dendrite development GO:0016358 204 0.012
chemotaxis GO:0006935 249 0.012
negative regulation of cellular biosynthetic process GO:0031327 277 0.012
sex determination GO:0007530 18 0.012
regulation of multicellular organism growth GO:0040014 40 0.012
jak stat cascade GO:0007259 49 0.012
mrna splicing via spliceosome GO:0000398 73 0.012
mrna processing GO:0006397 104 0.012
negative regulation of gene expression epigenetic GO:0045814 77 0.012
regulation of proteolysis GO:0030162 87 0.012
regulation of catabolic process GO:0009894 170 0.012
regulation of neuron projection development GO:0010975 69 0.011
positive regulation of ras protein signal transduction GO:0046579 43 0.011
gtp metabolic process GO:0046039 72 0.011
multicellular organismal reproductive behavior GO:0033057 110 0.011
rhythmic process GO:0048511 106 0.011
response to wounding GO:0009611 94 0.011
regulation of mitosis GO:0007088 56 0.011
rna splicing GO:0008380 83 0.011
regulation of nuclear division GO:0051783 58 0.011
organelle localization GO:0051640 148 0.011
gliogenesis GO:0042063 80 0.011
embryonic development via the syncytial blastoderm GO:0001700 148 0.011
cell junction assembly GO:0034329 42 0.011
response to alcohol GO:0097305 95 0.011
cell cell junction organization GO:0045216 55 0.011
histone acetylation GO:0016573 38 0.011
catabolic process GO:0009056 409 0.011
cellular nitrogen compound catabolic process GO:0044270 165 0.010
regulation of multi organism process GO:0043900 131 0.010
cell junction organization GO:0034330 57 0.010
stress activated protein kinase signaling cascade GO:0031098 55 0.010
chitin based larval cuticle pattern formation GO:0035293 11 0.010
regulation of response to external stimulus GO:0032101 115 0.010
dna metabolic process GO:0006259 227 0.010
oxoacid metabolic process GO:0043436 103 0.010
purine nucleoside triphosphate metabolic process GO:0009144 119 0.010
organic cyclic compound catabolic process GO:1901361 168 0.010
response to axon injury GO:0048678 12 0.010

fl(2)d disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

Disease DO term ID Size Probability Func Analog Org
cancer DOID:162 0 0.023
disease of cellular proliferation DOID:14566 0 0.023
organ system cancer DOID:0050686 0 0.011