Drosophila melanogaster

0 known processes

alpha-Est4 (Dmel_CG1082)

alpha-Esterase-4

(Aliases: alphaE4,C,aE4,DmalphaE4,Dmel\CG1082,CG1082)

alpha-Est4 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
small molecule metabolic process GO:0044281 305 0.095
Fly
response to abiotic stimulus GO:0009628 341 0.053
Fly
vesicle mediated transport GO:0016192 381 0.051
steroid catabolic process GO:0006706 1 0.047
response to other organism GO:0051707 293 0.046
Fly
sensory perception of chemical stimulus GO:0007606 116 0.046
endocytosis GO:0006897 310 0.046
organic acid metabolic process GO:0006082 103 0.045
imaginal disc derived appendage development GO:0048737 399 0.044
Fly
wing disc morphogenesis GO:0007472 344 0.044
Fly
imaginal disc derived appendage morphogenesis GO:0035114 395 0.043
Fly
neurological system process GO:0050877 358 0.043
cellular response to ethanol GO:0071361 4 0.042
chaeta development GO:0022416 97 0.042
response to external biotic stimulus GO:0043207 293 0.042
Fly
xenobiotic catabolic process GO:0042178 1 0.041
positive regulation of response to stimulus GO:0048584 323 0.040
appendage morphogenesis GO:0035107 397 0.040
Fly
oxoacid metabolic process GO:0043436 103 0.040
phagocytosis GO:0006909 215 0.040
hormone catabolic process GO:0042447 3 0.039
intracellular signal transduction GO:0035556 300 0.039
response to nutrient levels GO:0031667 114 0.038
organonitrogen compound metabolic process GO:1901564 318 0.038
Fly
negative regulation of gene expression GO:0010629 387 0.037
response to oxygen containing compound GO:1901700 200 0.037
immune response GO:0006955 246 0.037
post embryonic appendage morphogenesis GO:0035120 385 0.036
Fly
lateral inhibition GO:0046331 206 0.036
defense response GO:0006952 300 0.035
Fly
response to lipopolysaccharide GO:0032496 4 0.035
estrogen metabolic process GO:0008210 1 0.035
protein modification process GO:0036211 438 0.035
response to organic substance GO:0010033 284 0.035
Fly
cell cell signaling involved in cell fate commitment GO:0045168 210 0.034
carboxylic acid metabolic process GO:0019752 92 0.033
cellular amino acid metabolic process GO:0006520 61 0.032
cellular protein modification process GO:0006464 438 0.031
response to biotic stimulus GO:0009607 294 0.031
Fly
cellular catabolic process GO:0044248 372 0.031
Fly
appendage development GO:0048736 401 0.031
Fly
sensory perception GO:0007600 196 0.029
organic hydroxy compound metabolic process GO:1901615 83 0.029
Fly
response to radiation GO:0009314 155 0.029
Fly
immune system process GO:0002376 347 0.029
regulation of intracellular signal transduction GO:1902531 236 0.029
organic substance transport GO:0071702 257 0.029
homeostatic process GO:0042592 199 0.028
benzene containing compound metabolic process GO:0042537 3 0.028
androgen metabolic process GO:0008209 1 0.027
organic substance catabolic process GO:1901575 308 0.027
Fly
gland development GO:0048732 191 0.027
regionalization GO:0003002 416 0.026
Fly
catabolic process GO:0009056 409 0.026
Fly
cellular ketone metabolic process GO:0042180 24 0.026
cholesterol homeostasis GO:0042632 3 0.026
phosphorylation GO:0016310 294 0.025
positive regulation of cell communication GO:0010647 250 0.025
forebrain development GO:0030900 2 0.025
response to extracellular stimulus GO:0009991 116 0.024
positive regulation of signaling GO:0023056 243 0.024
ovarian follicle cell development GO:0030707 248 0.023
Fly
imaginal disc derived wing morphogenesis GO:0007476 337 0.023
Fly
defense response to bacterium GO:0042742 178 0.023
negative regulation of response to stimulus GO:0048585 258 0.023
negative regulation of cellular metabolic process GO:0031324 382 0.023
death GO:0016265 284 0.023
positive regulation of nitrogen compound metabolic process GO:0051173 354 0.023
positive regulation of signal transduction GO:0009967 223 0.023
single organism biosynthetic process GO:0044711 206 0.022
lipid metabolic process GO:0006629 121 0.022
single organism behavior GO:0044708 391 0.022
regulation of localization GO:0032879 275 0.022
single organism catabolic process GO:0044712 228 0.022
Fly
polyol biosynthetic process GO:0046173 3 0.021
cell death GO:0008219 279 0.021
regulation of response to stress GO:0080134 200 0.021
camera type eye development GO:0043010 4 0.021
body morphogenesis GO:0010171 2 0.021
regulation of cellular ketone metabolic process GO:0010565 3 0.021
l glutamate import GO:0051938 1 0.021
regulation of multicellular organismal development GO:2000026 414 0.021
developmental growth GO:0048589 280 0.021
sterol homeostasis GO:0055092 4 0.021
cellular response to chemical stimulus GO:0070887 199 0.021
response to light stimulus GO:0009416 124 0.020
Fly
nuclear division GO:0000280 332 0.020
Fly
positive regulation of nucleobase containing compound metabolic process GO:0045935 332 0.020
response to temperature stimulus GO:0009266 106 0.020
amine metabolic process GO:0009308 12 0.020
Fly
response to alcohol GO:0097305 95 0.020
response to starvation GO:0042594 97 0.020
organic cyclic compound catabolic process GO:1901361 168 0.020
establishment of localization in cell GO:0051649 402 0.020
taxis GO:0042330 304 0.020
Fly
regulation of cellular amine metabolic process GO:0033238 3 0.020
response to ethanol GO:0045471 59 0.020
cellular macromolecule localization GO:0070727 220 0.019
salivary gland development GO:0007431 162 0.019
innate immune response GO:0045087 144 0.019
defense response to other organism GO:0098542 225 0.019
Fly
regulation of phosphorus metabolic process GO:0051174 210 0.019
organelle fission GO:0048285 340 0.019
Fly
transcription from rna polymerase ii promoter GO:0006366 368 0.019
cellular response to organic substance GO:0071310 132 0.019
positive regulation of cellular biosynthetic process GO:0031328 316 0.019
positive regulation of biosynthetic process GO:0009891 316 0.019
salivary gland morphogenesis GO:0007435 145 0.019
response to monosaccharide GO:0034284 4 0.019
aggressive behavior GO:0002118 63 0.018
aromatic compound catabolic process GO:0019439 166 0.018
positive regulation of macromolecule metabolic process GO:0010604 405 0.018
response to copper ion GO:0046688 4 0.018
regulation of cellular amino acid metabolic process GO:0006521 0 0.018
negative regulation of signaling GO:0023057 219 0.018
protein localization GO:0008104 284 0.018
epithelial cell development GO:0002064 274 0.018
Fly
actin filament based process GO:0030029 220 0.018
regulation of phosphate metabolic process GO:0019220 210 0.018
regulation of protein metabolic process GO:0051246 256 0.018
proteolysis GO:0006508 192 0.018
response to bacterium GO:0009617 198 0.018
response to organic cyclic compound GO:0014070 89 0.018
heterocycle catabolic process GO:0046700 166 0.018
rhythmic process GO:0048511 106 0.018
vitamin metabolic process GO:0006766 2 0.018
morphogenesis of an epithelium GO:0002009 276 0.018
kidney development GO:0001822 3 0.018
negative regulation of cell communication GO:0010648 223 0.018
regulation of catalytic activity GO:0050790 185 0.018
ethanolamine containing compound metabolic process GO:0042439 4 0.018
Fly
adult behavior GO:0030534 137 0.017
response to endogenous stimulus GO:0009719 119 0.017
regulation of molecular function GO:0065009 217 0.017
programmed cell death GO:0012501 257 0.017
regulation of cellular protein metabolic process GO:0032268 243 0.017
localization of cell GO:0051674 257 0.017
Fly
cell migration GO:0016477 238 0.017
Fly
chemical homeostasis GO:0048878 92 0.017
tissue morphogenesis GO:0048729 297 0.017
organophosphate metabolic process GO:0019637 195 0.017
regulation of cell cycle GO:0051726 291 0.017
negative regulation of signal transduction GO:0009968 206 0.017
carbohydrate derivative metabolic process GO:1901135 217 0.017
anion homeostasis GO:0055081 3 0.017
glycerolipid catabolic process GO:0046503 3 0.017
sensory perception of smell GO:0007608 80 0.017
epithelial cell differentiation GO:0030855 322 0.017
Fly
positive regulation of gene expression GO:0010628 290 0.016
negative regulation of nitrogen compound metabolic process GO:0051172 265 0.016
synaptic transmission GO:0007268 288 0.016
Fly
compound eye development GO:0048749 307 0.016
negative regulation of macromolecule biosynthetic process GO:0010558 270 0.016
insecticide metabolic process GO:0017143 2 0.016
cellular amine metabolic process GO:0044106 12 0.016
Fly
ion transport GO:0006811 145 0.016
regulation of transcription from rna polymerase ii promoter GO:0006357 378 0.016
secondary metabolite catabolic process GO:0090487 1 0.016
response to organophosphorus GO:0046683 2 0.016
Fly
fat soluble vitamin metabolic process GO:0006775 1 0.016
intracellular transport GO:0046907 228 0.016
telencephalon development GO:0021537 2 0.016
response to glucose GO:0009749 2 0.016
compound eye morphogenesis GO:0001745 249 0.016
protein transport GO:0015031 155 0.016
columnar cuboidal epithelial cell development GO:0002066 249 0.015
Fly
response to wounding GO:0009611 94 0.015
central nervous system development GO:0007417 201 0.015
cell motility GO:0048870 251 0.015
Fly
cellular protein localization GO:0034613 160 0.015
positive regulation of cell migration GO:0030335 2 0.015
positive regulation of rna biosynthetic process GO:1902680 266 0.015
cell proliferation GO:0008283 299 0.015
triglyceride biosynthetic process GO:0019432 2 0.015
negative regulation of cellular biosynthetic process GO:0031327 277 0.015
regulation of cell death GO:0010941 173 0.015
axon development GO:0061564 297 0.015
Fly
growth GO:0040007 359 0.015
response to hexose GO:0009746 3 0.015
negative regulation of biosynthetic process GO:0009890 277 0.015
inter male aggressive behavior GO:0002121 60 0.015
dorsal ventral pattern formation GO:0009953 133 0.015
macromolecular complex assembly GO:0065003 256 0.015
connective tissue development GO:0061448 3 0.015
acylglycerol catabolic process GO:0046464 3 0.015
positive regulation of nucleic acid templated transcription GO:1903508 266 0.015
exocrine system development GO:0035272 162 0.015
gland morphogenesis GO:0022612 145 0.015
eye morphogenesis GO:0048592 260 0.015
toxin catabolic process GO:0009407 1 0.015
regulation of cellular component biogenesis GO:0044087 201 0.015
cellular response to dna damage stimulus GO:0006974 223 0.015
positive regulation of cell motility GO:2000147 3 0.014
cellular homeostasis GO:0019725 80 0.014
developmental programmed cell death GO:0010623 138 0.014
regulation of cell cycle process GO:0010564 181 0.014
medium chain fatty acid metabolic process GO:0051791 1 0.014
g protein coupled receptor signaling pathway GO:0007186 136 0.014
columnar cuboidal epithelial cell differentiation GO:0002065 256 0.014
Fly
nucleoside phosphate metabolic process GO:0006753 162 0.014
wound healing GO:0042060 75 0.014
eye development GO:0001654 323 0.014
response to nitrogen compound GO:1901698 90 0.014
establishment of protein localization GO:0045184 163 0.014
cellular component assembly involved in morphogenesis GO:0010927 151 0.014
regulation of anatomical structure size GO:0090066 163 0.014
Fly
regulation of transport GO:0051049 181 0.014
nucleobase containing small molecule metabolic process GO:0055086 174 0.014
protein phosphorylation GO:0006468 169 0.014
detection of chemical stimulus GO:0009593 93 0.014
humoral immune response GO:0006959 117 0.014
small gtpase mediated signal transduction GO:0007264 88 0.014
imaginal disc pattern formation GO:0007447 91 0.014
neuron projection guidance GO:0097485 241 0.014
Fly
single organism intracellular transport GO:1902582 207 0.014
single organism carbohydrate metabolic process GO:0044723 72 0.014
neuropeptide signaling pathway GO:0007218 45 0.014
cellular response to molecule of bacterial origin GO:0071219 3 0.014
cellular nitrogen compound catabolic process GO:0044270 165 0.014
chromosome organization GO:0051276 360 0.014
negative regulation of developmental process GO:0051093 201 0.014
immune response activating signal transduction GO:0002757 2 0.013
response to alkaloid GO:0043279 26 0.013
purine ribonucleotide metabolic process GO:0009150 145 0.013
l amino acid import GO:0043092 2 0.013
positive regulation of molecular function GO:0044093 136 0.013
purine nucleotide metabolic process GO:0006163 146 0.013
neutral lipid catabolic process GO:0046461 3 0.013
chemotaxis GO:0006935 249 0.013
Fly
detection of stimulus GO:0051606 156 0.013
acylglycerol biosynthetic process GO:0046463 2 0.013
positive regulation of macromolecule biosynthetic process GO:0010557 283 0.013
positive regulation of phosphorus metabolic process GO:0010562 139 0.013
detection of stimulus involved in sensory perception GO:0050906 92 0.013
epithelial cell migration GO:0010631 148 0.013
Fly
gene silencing GO:0016458 138 0.013
male gamete generation GO:0048232 201 0.013
Fly
axonogenesis GO:0007409 290 0.013
Fly
immune response regulating signaling pathway GO:0002764 2 0.013
cellular response to oxygen containing compound GO:1901701 79 0.013
axon guidance GO:0007411 233 0.013
Fly
positive regulation of rna metabolic process GO:0051254 271 0.013
activation of innate immune response GO:0002218 4 0.013
positive regulation of transcription dna templated GO:0045893 266 0.013
positive regulation of lipid storage GO:0010884 4 0.013
negative regulation of nucleic acid templated transcription GO:1903507 240 0.013
single organism cellular localization GO:1902580 180 0.013
open tracheal system development GO:0007424 204 0.013
Fly
aging GO:0007568 143 0.013
Fly
developmental maturation GO:0021700 172 0.013
ameboidal type cell migration GO:0001667 151 0.013
Fly
hindbrain development GO:0030902 2 0.013
actin cytoskeleton organization GO:0030036 206 0.013
ras protein signal transduction GO:0007265 88 0.013
cellular hormone metabolic process GO:0034754 23 0.013
triglyceride catabolic process GO:0019433 3 0.013
regulation of catabolic process GO:0009894 170 0.013
carbohydrate metabolic process GO:0005975 82 0.013
negative regulation of cellular macromolecule biosynthetic process GO:2000113 267 0.013
negative regulation of nucleobase containing compound metabolic process GO:0045934 261 0.013
lauric acid metabolic process GO:0048252 1 0.013
hormone metabolic process GO:0042445 33 0.013
segmentation GO:0035282 207 0.013
peptidyl amino acid modification GO:0018193 105 0.013
regulation of hormone levels GO:0010817 40 0.013
positive regulation of intracellular signal transduction GO:1902533 116 0.013
protein complex biogenesis GO:0070271 201 0.013
sensory organ morphogenesis GO:0090596 260 0.012
phosphate ion transport GO:0006817 4 0.012
maintenance of location GO:0051235 73 0.012
Fly
purine containing compound metabolic process GO:0072521 155 0.012
cuticle development GO:0042335 86 0.012
negative regulation of rna metabolic process GO:0051253 251 0.012
regulation of anatomical structure morphogenesis GO:0022603 242 0.012
nucleotide metabolic process GO:0009117 161 0.012
positive regulation of phosphate metabolic process GO:0045937 139 0.012
histolysis GO:0007559 102 0.012
cellular lipid metabolic process GO:0044255 83 0.012
mitotic cell cycle phase transition GO:0044772 138 0.012
regulation of programmed cell death GO:0043067 152 0.012
embryonic development via the syncytial blastoderm GO:0001700 148 0.012
limb development GO:0060173 1 0.012
secondary metabolic process GO:0019748 75 0.012
chromatin modification GO:0016568 147 0.012
regulation of sequestering of triglyceride GO:0010889 3 0.012
cellular response to endogenous stimulus GO:0071495 80 0.012
vitamin biosynthetic process GO:0009110 1 0.012
regulation of cellular response to stress GO:0080135 89 0.012
cell cycle phase transition GO:0044770 140 0.012
fat soluble vitamin biosynthetic process GO:0042362 1 0.012
camera type eye morphogenesis GO:0048593 2 0.012
neutral lipid biosynthetic process GO:0046460 2 0.012
locomotory behavior GO:0007626 176 0.012
regulation of cellular catabolic process GO:0031329 157 0.012
dendrite morphogenesis GO:0048813 199 0.012
cellular response to lipopolysaccharide GO:0071222 3 0.012
ribose phosphate metabolic process GO:0019693 145 0.012
cellular response to carbohydrate stimulus GO:0071322 4 0.012
negative regulation of multicellular organismal process GO:0051241 142 0.012
regulation of phosphorylation GO:0042325 147 0.012
regulation of synapse structure and activity GO:0050803 128 0.012
actin filament organization GO:0007015 126 0.012
multi organism behavior GO:0051705 175 0.012
Fly
regulation of gene expression epigenetic GO:0040029 128 0.012
chemosensory behavior GO:0007635 106 0.012
cation transport GO:0006812 110 0.012
organonitrogen compound catabolic process GO:1901565 128 0.012
Fly
positive regulation of catalytic activity GO:0043085 118 0.012
cellular response to biotic stimulus GO:0071216 4 0.012
protein complex assembly GO:0006461 200 0.012
regulation of i kappab kinase nf kappab signaling GO:0043122 2 0.012
ribonucleotide metabolic process GO:0009259 145 0.011
regulation of cell differentiation GO:0045595 302 0.011
defense response to gram negative bacterium GO:0050829 94 0.011
posttranscriptional regulation of gene expression GO:0010608 145 0.011
pattern recognition receptor signaling pathway GO:0002221 2 0.011
regulation of growth GO:0040008 233 0.011
tissue migration GO:0090130 155 0.011
Fly
rna localization GO:0006403 115 0.011
chromatin organization GO:0006325 207 0.011
positive regulation of multicellular organismal process GO:0051240 143 0.011
negative regulation of rna biosynthetic process GO:1902679 240 0.011
detection of chemical stimulus involved in sensory perception GO:0050907 75 0.011
signal transduction by phosphorylation GO:0023014 107 0.011
regulation of lipid transport GO:0032368 3 0.011
organophosphate catabolic process GO:0046434 112 0.011
protein hydroxylation GO:0018126 1 0.011
enzyme linked receptor protein signaling pathway GO:0007167 179 0.011
respiratory system development GO:0060541 213 0.011
Fly
regulation of cellular localization GO:0060341 136 0.011
salivary gland histolysis GO:0035070 88 0.011
regulation of nervous system development GO:0051960 248 0.011
apoptotic process GO:0006915 159 0.011
synapse assembly GO:0007416 143 0.011
retina development in camera type eye GO:0060041 4 0.011
monocarboxylic acid transport GO:0015718 3 0.011
salivary gland cell autophagic cell death GO:0035071 83 0.011
positive regulation of catabolic process GO:0009896 105 0.011
axis specification GO:0009798 167 0.011
wnt signaling pathway GO:0016055 98 0.011
regulation of cell substrate adhesion GO:0010810 2 0.011
dna metabolic process GO:0006259 227 0.011
phosphatidylethanolamine metabolic process GO:0046337 1 0.011
regulation of organelle organization GO:0033043 196 0.011
response to mercury ion GO:0046689 3 0.011
cell division GO:0051301 248 0.011
regulation of multi organism process GO:0043900 131 0.011
intracellular protein transport GO:0006886 104 0.011
cellular macromolecular complex assembly GO:0034622 153 0.011
sodium dependent phosphate transport GO:0044341 2 0.011
peptidyl proline hydroxylation GO:0019511 1 0.011
biological adhesion GO:0022610 138 0.011
Fly
regulation of immune system process GO:0002682 176 0.011
molting cycle chitin based cuticle GO:0007591 56 0.011
phospholipid homeostasis GO:0055091 1 0.011
macromolecule catabolic process GO:0009057 161 0.011
embryonic pattern specification GO:0009880 174 0.011
dendrite development GO:0016358 204 0.011
innate immune response activating signal transduction GO:0002758 2 0.011
regulation of developmental growth GO:0048638 174 0.011
multicellular organismal aging GO:0010259 140 0.011
Fly
negative regulation of transcription dna templated GO:0045892 237 0.011
secretion GO:0046903 109 0.011
regulation of epithelial cell proliferation GO:0050678 4 0.010
leg disc morphogenesis GO:0007478 80 0.010
peptidyl proline modification GO:0018208 3 0.010
behavioral response to pain GO:0048266 3 0.010
positive regulation of cellular amine metabolic process GO:0033240 0 0.010
regulation of immune response GO:0050776 118 0.010
regulation of mitotic cell cycle GO:0007346 190 0.010
mapk cascade GO:0000165 107 0.010
acetate ester metabolic process GO:1900619 2 0.010
Fly
acetylcholine metabolic process GO:0008291 2 0.010
Fly
negative regulation of protein metabolic process GO:0051248 85 0.010
cytoplasmic transport GO:0016482 130 0.010
protein heterooligomerization GO:0051291 4 0.010
mesoderm development GO:0007498 78 0.010
blastoderm segmentation GO:0007350 159 0.010
regulation of hydrolase activity GO:0051336 97 0.010
ion homeostasis GO:0050801 55 0.010
positive regulation of cellular component organization GO:0051130 156 0.010
spermatogenesis GO:0007283 200 0.010
Fly
carbohydrate derivative biosynthetic process GO:1901137 85 0.010
negative regulation of cellular protein metabolic process GO:0032269 85 0.010
response to pain GO:0048265 3 0.010
regulation of epithelial cell differentiation GO:0030856 4 0.010
sensory perception of pain GO:0019233 4 0.010
hematopoietic progenitor cell differentiation GO:0002244 1 0.010
synapse organization GO:0050808 196 0.010
drinking behavior GO:0042756 2 0.010
positive regulation of cellular amino acid metabolic process GO:0045764 0 0.010
determination of adult lifespan GO:0008340 137 0.010
Fly
response to heat GO:0009408 63 0.010

alpha-Est4 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.073
disease of metabolism DOID:0014667 0 0.023
nervous system disease DOID:863 0 0.023
kidney disease DOID:557 0 0.022
urinary system disease DOID:18 0 0.022
renal tubular transport disease DOID:447 0 0.022
musculoskeletal system disease DOID:17 0 0.022
cardiovascular system disease DOID:1287 0 0.021
vascular disease DOID:178 0 0.018
artery disease DOID:0050828 0 0.018
inherited metabolic disorder DOID:655 0 0.017
acquired metabolic disease DOID:0060158 0 0.015
diabetes mellitus DOID:9351 0 0.013
glucose metabolism disease DOID:4194 0 0.013
carbohydrate metabolism disease DOID:0050013 0 0.013
type 2 diabetes mellitus DOID:9352 0 0.013
sensory system disease DOID:0050155 0 0.012
essential hypertension DOID:10825 0 0.012
hypertension DOID:10763 0 0.012
connective tissue disease DOID:65 0 0.012
bone disease DOID:0080001 0 0.011
eye and adnexa disease DOID:1492 0 0.011
eye disease DOID:5614 0 0.011
central nervous system disease DOID:331 0 0.011