Drosophila melanogaster

158 known processes

Smn (Dmel_CG16725)

survival motor neuron

(Aliases: Dmel\CG16725,smn,CG16725,SMN,dSMN,DmSMN,l(3)73Ao)

Smn biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
mrna metabolic process GO:0016071 124 0.469
cell proliferation GO:0008283 299 0.406
mrna processing GO:0006397 104 0.303
rna splicing via transesterification reactions with bulged adenosine as nucleophile GO:0000377 73 0.281
nuclear division GO:0000280 332 0.270
organelle fission GO:0048285 340 0.267
regulation of meiosis GO:0040020 3 0.235
chromatin modification GO:0016568 147 0.181
chromatin organization GO:0006325 207 0.178
chromosome organization GO:0051276 360 0.143
regulation of cell cycle GO:0051726 291 0.137
Worm
protein modification process GO:0036211 438 0.137
histone modification GO:0016570 106 0.132
regulation of multicellular organismal development GO:2000026 414 0.129
mitotic g2 dna damage checkpoint GO:0007095 69 0.126
regulation of organelle organization GO:0033043 196 0.098
embryo development ending in birth or egg hatching GO:0009792 152 0.094
Worm
positive regulation of cellular protein metabolic process GO:0032270 118 0.094
covalent chromatin modification GO:0016569 106 0.093
cell motility GO:0048870 251 0.092
rna splicing GO:0008380 83 0.085
rna processing GO:0006396 147 0.085
endocytosis GO:0006897 310 0.084
organelle assembly GO:0070925 198 0.074
regulation of cell cycle process GO:0010564 181 0.074
dna conformation change GO:0071103 105 0.073
vesicle mediated transport GO:0016192 381 0.069
rna splicing via transesterification reactions GO:0000375 73 0.065
positive regulation of gene expression GO:0010628 290 0.063
mrna splicing via spliceosome GO:0000398 73 0.059
negative regulation of gene expression GO:0010629 387 0.058
regulation of mitotic cell cycle phase transition GO:1901990 130 0.058
regulation of cell death GO:0010941 173 0.055
positive regulation of biosynthetic process GO:0009891 316 0.050
regionalization GO:0003002 416 0.048
centrosome organization GO:0051297 163 0.047
positive regulation of protein metabolic process GO:0051247 128 0.047
ribonucleoprotein complex subunit organization GO:0071826 28 0.047
phosphorylation GO:0016310 294 0.047
positive regulation of transcription from rna polymerase i promoter GO:0045943 3 0.046
cellular protein modification process GO:0006464 438 0.044
histone methylation GO:0016571 40 0.043
localization of cell GO:0051674 257 0.043
regulation of apoptotic process GO:0042981 130 0.039
regulation of protein metabolic process GO:0051246 256 0.038
negative regulation of cell death GO:0060548 81 0.037
macromolecular complex assembly GO:0065003 256 0.036
positive regulation of macromolecule biosynthetic process GO:0010557 283 0.034
cytoplasmic transport GO:0016482 130 0.033
wing disc morphogenesis GO:0007472 344 0.032
regulation of cell differentiation GO:0045595 302 0.031
phagocytosis GO:0006909 215 0.031
peptidyl amino acid modification GO:0018193 105 0.031
regulation of cellular protein metabolic process GO:0032268 243 0.030
programmed cell death GO:0012501 257 0.030
regulation of transcription from rna polymerase ii promoter GO:0006357 378 0.029
positive regulation of response to stimulus GO:0048584 323 0.029
cell migration GO:0016477 238 0.028
positive regulation of signal transduction GO:0009967 223 0.028
ribonucleoprotein complex biogenesis GO:0022613 31 0.027
dna packaging GO:0006323 91 0.027
regulation of cell proliferation GO:0042127 163 0.026
regulation of rac gtpase activity GO:0032314 1 0.026
positive regulation of cellular biosynthetic process GO:0031328 316 0.026
cell death GO:0008219 279 0.026
spindle organization GO:0007051 253 0.025
cellular response to dna damage stimulus GO:0006974 223 0.025
mitochondrial membrane organization GO:0007006 3 0.025
regulation of mitotic cell cycle GO:0007346 190 0.025
Worm
imaginal disc derived wing morphogenesis GO:0007476 337 0.025
death GO:0016265 284 0.024
cell division GO:0051301 248 0.023
spindle assembly involved in mitosis GO:0090307 50 0.023
peptidyl lysine methylation GO:0018022 16 0.023
regulation of phosphorus metabolic process GO:0051174 210 0.023
regulation of phosphate metabolic process GO:0019220 210 0.023
mitotic spindle organization GO:0007052 220 0.023
regulation of chromatin organization GO:1902275 32 0.022
ribonucleoprotein complex assembly GO:0022618 23 0.021
positive regulation of signaling GO:0023056 243 0.021
establishment of localization in cell GO:0051649 402 0.021
rna localization GO:0006403 115 0.021
regulation of cell division GO:0051302 72 0.020
positive regulation of rna biosynthetic process GO:1902680 266 0.020
mitotic g2 m transition checkpoint GO:0044818 70 0.020
positive regulation of organelle organization GO:0010638 65 0.020
nucleobase containing compound catabolic process GO:0034655 165 0.019
anatomical structure homeostasis GO:0060249 97 0.019
posttranscriptional gene silencing by rna GO:0035194 45 0.019
appendage morphogenesis GO:0035107 397 0.019
regulation of protein modification process GO:0031399 112 0.019
regulation of response to stress GO:0080134 200 0.019
establishment or maintenance of cell polarity GO:0007163 167 0.019
regulation of cell development GO:0060284 215 0.018
positive regulation of nitrogen compound metabolic process GO:0051173 354 0.018
peptidyl lysine trimethylation GO:0018023 6 0.018
centrosome cycle GO:0007098 137 0.017
intracellular transport GO:0046907 228 0.017
rna catabolic process GO:0006401 37 0.017
intracellular signal transduction GO:0035556 300 0.017
mrna transport GO:0051028 15 0.017
negative regulation of cellular biosynthetic process GO:0031327 277 0.016
negative regulation of phosphate metabolic process GO:0045936 45 0.016
regulation of programmed cell death GO:0043067 152 0.016
regulation of cell shape GO:0008360 113 0.016
regulation of intracellular signal transduction GO:1902531 236 0.015
posttranscriptional regulation of gene expression GO:0010608 145 0.015
positive regulation of cellular component organization GO:0051130 156 0.014
regulation of chromatin modification GO:1903308 28 0.014
catabolic process GO:0009056 409 0.014
regulation of transcription from rna polymerase i promoter GO:0006356 4 0.014
post embryonic appendage morphogenesis GO:0035120 385 0.014
response to abiotic stimulus GO:0009628 341 0.014
cellular lipid metabolic process GO:0044255 83 0.014
larval development GO:0002164 104 0.013
negative regulation of transcription dna templated GO:0045892 237 0.013
chromatin remodeling GO:0006338 72 0.013
positive regulation of nucleobase containing compound metabolic process GO:0045935 332 0.013
spindle assembly GO:0051225 80 0.013
blastoderm segmentation GO:0007350 159 0.013
carboxylic acid metabolic process GO:0019752 92 0.013
regulation of nervous system development GO:0051960 248 0.012
embryonic pattern specification GO:0009880 174 0.012
negative regulation of cell cycle process GO:0010948 109 0.012
organic substance catabolic process GO:1901575 308 0.012
regulation of gene expression epigenetic GO:0040029 128 0.012
positive regulation of cellular component biogenesis GO:0044089 80 0.012
positive regulation of nucleic acid templated transcription GO:1903508 266 0.012
actin filament based process GO:0030029 220 0.012
negative regulation of nucleic acid templated transcription GO:1903507 240 0.011
macromolecule catabolic process GO:0009057 161 0.011
microtubule cytoskeleton organization involved in mitosis GO:1902850 52 0.011
negative regulation of signal transduction GO:0009968 206 0.011
developmental maturation GO:0021700 172 0.011
regulation of histone modification GO:0031056 20 0.011
organic cyclic compound catabolic process GO:1901361 168 0.011
positive regulation of binding GO:0051099 4 0.011
cellular macromolecular complex assembly GO:0034622 153 0.011
negative regulation of apoptotic process GO:0043066 63 0.011
protein alkylation GO:0008213 43 0.011
meiotic nuclear division GO:0007126 151 0.011
microtubule organizing center organization GO:0031023 168 0.010
cellular macromolecule catabolic process GO:0044265 136 0.010
positive regulation of transcription dna templated GO:0045893 266 0.010
mitotic cytokinesis GO:0000281 50 0.010
positive regulation of rna metabolic process GO:0051254 271 0.010
regulation of meiotic cell cycle GO:0051445 9 0.010
Worm
dna alkylation GO:0006305 4 0.010
mitotic nuclear division GO:0007067 213 0.010
imaginal disc derived appendage development GO:0048737 399 0.010

Smn disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.025
Human
neurodegenerative disease DOID:1289 0 0.025
Human
nervous system disease DOID:863 0 0.025
Human
central nervous system disease DOID:331 0 0.025
Human