Drosophila melanogaster

7 known processes

Git (Dmel_CG16728)

CG16728 gene product from transcript CG16728-RA

(Aliases: dgit,CG16728,arfgap2,CT37209,Dmel\CG16728)

Git biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
localization of cell GO:0051674 257 0.638
response to other organism GO:0051707 293 0.619
protein localization GO:0008104 284 0.602
intracellular transport GO:0046907 228 0.584
cell migration GO:0016477 238 0.566
regulation of small gtpase mediated signal transduction GO:0051056 93 0.565
cell motility GO:0048870 251 0.532
positive regulation of macromolecule metabolic process GO:0010604 405 0.492
ras protein signal transduction GO:0007265 88 0.429
organonitrogen compound catabolic process GO:1901565 128 0.326
Rat Fly
regulation of protein transport GO:0051223 57 0.320
single organism intracellular transport GO:1902582 207 0.303
positive regulation of phosphate metabolic process GO:0045937 139 0.299
Rat Fly
biological adhesion GO:0022610 138 0.290
purine ribonucleoside triphosphate metabolic process GO:0009205 119 0.273
Rat Fly
glycosyl compound catabolic process GO:1901658 112 0.272
Rat Fly
chromosome organization GO:0051276 360 0.270
nuclear division GO:0000280 332 0.263
positive regulation of hydrolase activity GO:0051345 78 0.253
Rat Fly
establishment of localization in cell GO:0051649 402 0.249
cytoplasmic transport GO:0016482 130 0.247
single organism cellular localization GO:1902580 180 0.232
regulation of intracellular signal transduction GO:1902531 236 0.225
organelle fission GO:0048285 340 0.216
purine nucleotide metabolic process GO:0006163 146 0.211
Rat Fly
regulation of ras protein signal transduction GO:0046578 93 0.208
cellular amine metabolic process GO:0044106 12 0.205
regulation of cellular amine metabolic process GO:0033238 3 0.203
amine metabolic process GO:0009308 12 0.199
post embryonic appendage morphogenesis GO:0035120 385 0.194
nucleotide catabolic process GO:0009166 109 0.193
Rat Fly
mitotic nuclear division GO:0007067 213 0.190
regulation of catabolic process GO:0009894 170 0.183
Rat Fly
positive regulation of phosphorus metabolic process GO:0010562 139 0.179
Rat Fly
regulation of localization GO:0032879 275 0.174
regulation of organelle organization GO:0033043 196 0.174
organonitrogen compound metabolic process GO:1901564 318 0.171
Rat Fly
positive regulation of nitrogen compound metabolic process GO:0051173 354 0.166
Rat Fly
digestive tract development GO:0048565 149 0.154
response to oxygen containing compound GO:1901700 200 0.151
organic substance transport GO:0071702 257 0.148
intracellular protein transport GO:0006886 104 0.142
small gtpase mediated signal transduction GO:0007264 88 0.137
rna splicing GO:0008380 83 0.133
organic substance catabolic process GO:1901575 308 0.132
Rat Fly
intracellular signal transduction GO:0035556 300 0.132
organophosphate metabolic process GO:0019637 195 0.129
Rat Fly
regulation of phosphorus metabolic process GO:0051174 210 0.123
Rat Fly
positive regulation of catabolic process GO:0009896 105 0.116
Rat Fly
regulation of gtp catabolic process GO:0033124 44 0.114
Rat Fly
ribonucleoside triphosphate catabolic process GO:0009203 108 0.114
Rat Fly
somatic muscle development GO:0007525 66 0.113
cellular catabolic process GO:0044248 372 0.113
Rat Fly
ribonucleoside metabolic process GO:0009119 127 0.111
Rat Fly
regulation of molecular function GO:0065009 217 0.110
Rat Fly
purine nucleoside triphosphate catabolic process GO:0009146 108 0.110
Rat Fly
purine ribonucleotide catabolic process GO:0009154 109 0.107
Rat Fly
catabolic process GO:0009056 409 0.107
Rat Fly
cell death GO:0008219 279 0.103
tube morphogenesis GO:0035239 191 0.101
positive regulation of cellular catabolic process GO:0031331 95 0.100
Rat Fly
protein modification process GO:0036211 438 0.097
regulation of cell death GO:0010941 173 0.096
nucleoside phosphate catabolic process GO:1901292 110 0.095
Rat Fly
protein targeting to nucleus GO:0044744 51 0.094
digestive tract morphogenesis GO:0048546 127 0.093
regionalization GO:0003002 416 0.092
proteolysis GO:0006508 192 0.091
ribose phosphate metabolic process GO:0019693 145 0.090
Rat Fly
tube development GO:0035295 244 0.089
homeostatic process GO:0042592 199 0.084
columnar cuboidal epithelial cell differentiation GO:0002065 256 0.084
nuclear import GO:0051170 51 0.084
epithelial cell migration GO:0010631 148 0.083
purine nucleotide catabolic process GO:0006195 109 0.082
Rat Fly
regulation of cellular amino acid metabolic process GO:0006521 0 0.081
positive regulation of protein metabolic process GO:0051247 128 0.081
peptidyl amino acid modification GO:0018193 105 0.081
positive regulation of transport GO:0051050 92 0.079
nucleoside metabolic process GO:0009116 127 0.078
Rat Fly
cellular amino acid metabolic process GO:0006520 61 0.077
ameboidal type cell migration GO:0001667 151 0.076
epithelial tube morphogenesis GO:0060562 88 0.076
purine nucleoside triphosphate metabolic process GO:0009144 119 0.074
Rat Fly
nucleoside triphosphate metabolic process GO:0009141 120 0.073
Rat Fly
establishment or maintenance of cell polarity GO:0007163 167 0.072
chromatin organization GO:0006325 207 0.072
regulation of cellular localization GO:0060341 136 0.071
programmed cell death GO:0012501 257 0.070
cell division GO:0051301 248 0.070
regulation of hydrolase activity GO:0051336 97 0.068
Rat Fly
regulation of transport GO:0051049 181 0.068
positive regulation of ras gtpase activity GO:0032320 36 0.067
purine ribonucleoside metabolic process GO:0046128 127 0.067
Rat Fly
positive regulation of catalytic activity GO:0043085 118 0.066
Rat Fly
establishment of protein localization GO:0045184 163 0.066
regulation of mrna splicing via spliceosome GO:0048024 64 0.065
oxoacid metabolic process GO:0043436 103 0.065
digestive system development GO:0055123 149 0.065
wing disc morphogenesis GO:0007472 344 0.063
cellular protein localization GO:0034613 160 0.062
establishment of protein localization to organelle GO:0072594 62 0.060
regulation of apoptotic process GO:0042981 130 0.059
response to organic substance GO:0010033 284 0.058
purine nucleoside metabolic process GO:0042278 127 0.058
Rat Fly
response to abiotic stimulus GO:0009628 341 0.058
positive regulation of molecular function GO:0044093 136 0.057
Rat Fly
small molecule metabolic process GO:0044281 305 0.057
Rat Fly
embryonic morphogenesis GO:0048598 206 0.057
positive regulation of gtpase activity GO:0043547 43 0.056
Rat Fly
response to biotic stimulus GO:0009607 294 0.056
regulation of cellular protein metabolic process GO:0032268 243 0.055
purine containing compound metabolic process GO:0072521 155 0.055
Rat Fly
positive regulation of rna biosynthetic process GO:1902680 266 0.054
response to light stimulus GO:0009416 124 0.053
organelle localization GO:0051640 148 0.053
carbohydrate derivative catabolic process GO:1901136 118 0.052
Rat Fly
response to radiation GO:0009314 155 0.052
cellular ketone metabolic process GO:0042180 24 0.052
endocytosis GO:0006897 310 0.051
negative regulation of cell cycle GO:0045786 116 0.050
regulation of cellular ketone metabolic process GO:0010565 3 0.050
ribonucleotide metabolic process GO:0009259 145 0.049
Rat Fly
protein complex assembly GO:0006461 200 0.049
appendage morphogenesis GO:0035107 397 0.048
carboxylic acid metabolic process GO:0019752 92 0.048
protein targeting GO:0006605 64 0.048
positive regulation of intracellular signal transduction GO:1902533 116 0.047
regulation of mapk cascade GO:0043408 92 0.047
positive regulation of nucleoside metabolic process GO:0045979 47 0.047
Rat Fly
positive regulation of signal transduction GO:0009967 223 0.046
regulation of programmed cell death GO:0043067 152 0.045
ribonucleotide catabolic process GO:0009261 109 0.045
Rat Fly
nucleotide metabolic process GO:0009117 161 0.045
Rat Fly
single organism catabolic process GO:0044712 228 0.045
Rat Fly
positive regulation of multicellular organismal process GO:0051240 143 0.042
protein transport GO:0015031 155 0.041
regulation of catalytic activity GO:0050790 185 0.041
Rat Fly
tissue morphogenesis GO:0048729 297 0.040
single organism nuclear import GO:1902593 51 0.040
spindle organization GO:0007051 253 0.040
nucleocytoplasmic transport GO:0006913 72 0.040
regulation of cell morphogenesis GO:0022604 163 0.040
positive regulation of gtp catabolic process GO:0033126 43 0.039
Rat Fly
rna splicing via transesterification reactions GO:0000375 73 0.039
centrosome organization GO:0051297 163 0.039
positive regulation of cellular protein metabolic process GO:0032270 118 0.039
ovarian follicle cell development GO:0030707 248 0.038
protein import into nucleus GO:0006606 51 0.037
negative regulation of cell death GO:0060548 81 0.037
glycosyl compound metabolic process GO:1901657 127 0.037
Rat Fly
positive regulation of nucleobase containing compound metabolic process GO:0045935 332 0.037
Rat Fly
protein localization to organelle GO:0033365 82 0.037
guanosine containing compound catabolic process GO:1901069 74 0.037
Rat Fly
mrna splicing via spliceosome GO:0000398 73 0.037
signal transduction by phosphorylation GO:0023014 107 0.036
gene silencing by rna GO:0031047 57 0.036
regulation of cellular catabolic process GO:0031329 157 0.036
Rat Fly
leg disc development GO:0035218 92 0.036
positive regulation of nucleotide catabolic process GO:0030813 46 0.036
Rat Fly
axis specification GO:0009798 167 0.036
regulation of endocytosis GO:0030100 37 0.035
endomembrane system organization GO:0010256 119 0.035
regulation of phosphate metabolic process GO:0019220 210 0.035
Rat Fly
purine ribonucleoside catabolic process GO:0046130 112 0.035
Rat Fly
erk1 and erk2 cascade GO:0070371 39 0.035
purine ribonucleoside triphosphate catabolic process GO:0009207 108 0.035
Rat Fly
epithelial cell development GO:0002064 274 0.034
positive regulation of signaling GO:0023056 243 0.034
regulation of protein catabolic process GO:0042176 55 0.034
organic cyclic compound catabolic process GO:1901361 168 0.034
Rat Fly
purine ribonucleotide metabolic process GO:0009150 145 0.033
Rat Fly
cellular macromolecule localization GO:0070727 220 0.033
secretion GO:0046903 109 0.033
body morphogenesis GO:0010171 2 0.032
negative regulation of response to stimulus GO:0048585 258 0.032
positive regulation of cell communication GO:0010647 250 0.032
negative regulation of cell cycle process GO:0010948 109 0.031
secretion by cell GO:0032940 101 0.031
regulation of phosphorylation GO:0042325 147 0.030
regulation of intracellular transport GO:0032386 64 0.030
blastoderm segmentation GO:0007350 159 0.030
regulation of protein metabolic process GO:0051246 256 0.030
regulation of erk1 and erk2 cascade GO:0070372 39 0.030
meiotic cell cycle GO:0051321 171 0.030
cell adhesion GO:0007155 136 0.030
regulation of protein localization GO:0032880 76 0.029
purine containing compound catabolic process GO:0072523 112 0.029
Rat Fly
karyosome formation GO:0030717 22 0.029
anterior posterior axis specification GO:0009948 109 0.029
gtp catabolic process GO:0006184 72 0.028
Rat Fly
nucleobase containing compound catabolic process GO:0034655 165 0.028
Rat Fly
mapk cascade GO:0000165 107 0.028
single organism cell adhesion GO:0098602 47 0.028
positive regulation of transcription from rna polymerase ii promoter GO:0045944 204 0.027
morphogenesis of an epithelium GO:0002009 276 0.027
positive regulation of erk1 and erk2 cascade GO:0070374 36 0.027
nuclear transport GO:0051169 72 0.027
response to external biotic stimulus GO:0043207 293 0.026
meiotic cell cycle process GO:1903046 132 0.026
mitotic spindle organization GO:0007052 220 0.026
muscle structure development GO:0061061 224 0.026
positive regulation of mapk cascade GO:0043410 63 0.025
protein ubiquitination GO:0016567 70 0.025
death GO:0016265 284 0.025
nucleobase containing small molecule metabolic process GO:0055086 174 0.025
Rat Fly
epithelial cell differentiation GO:0030855 322 0.024
glial cell migration GO:0008347 31 0.024
regulation of cell cycle process GO:0010564 181 0.024
gtp metabolic process GO:0046039 72 0.024
Rat Fly
peptidyl lysine acetylation GO:0018394 39 0.024
positive regulation of cellular component organization GO:0051130 156 0.024
rac protein signal transduction GO:0016601 3 0.024
regulation of erbb signaling pathway GO:1901184 42 0.024
open tracheal system development GO:0007424 204 0.023
positive regulation of protein import into nucleus GO:0042307 21 0.023
purine nucleoside catabolic process GO:0006152 112 0.023
Rat Fly
positive regulation of phosphorylation GO:0042327 87 0.023
phosphorylation GO:0016310 294 0.023
positive regulation of purine nucleotide metabolic process GO:1900544 55 0.023
Rat Fly
regulation of epithelial cell proliferation GO:0050678 4 0.023
ribonucleoside triphosphate metabolic process GO:0009199 119 0.023
Rat Fly
dendrite morphogenesis GO:0048813 199 0.022
regulation of anatomical structure size GO:0090066 163 0.022
negative regulation of gene expression GO:0010629 387 0.022
reproductive system development GO:0061458 74 0.022
appendage development GO:0048736 401 0.022
salivary gland morphogenesis GO:0007435 145 0.022
organic acid metabolic process GO:0006082 103 0.022
imaginal disc derived appendage development GO:0048737 399 0.021
larval development GO:0002164 104 0.021
stem cell proliferation GO:0072089 88 0.021
ribonucleoside catabolic process GO:0042454 112 0.021
Rat Fly
positive regulation of response to stimulus GO:0048584 323 0.020
gonad development GO:0008406 50 0.020
golgi organization GO:0007030 66 0.020
vesicle mediated transport GO:0016192 381 0.020
regulation of nucleotide metabolic process GO:0006140 62 0.020
Rat Fly
regulation of transcription from rna polymerase ii promoter GO:0006357 378 0.020
negative regulation of mitotic cell cycle GO:0045930 109 0.020
cardiovascular system development GO:0072358 82 0.020
defense response to other organism GO:0098542 225 0.020
histone modification GO:0016570 106 0.019
regulation of locomotion GO:0040012 42 0.019
enzyme linked receptor protein signaling pathway GO:0007167 179 0.019
carbohydrate derivative metabolic process GO:1901135 217 0.019
Rat Fly
cellular protein modification process GO:0006464 438 0.019
microtubule organizing center organization GO:0031023 168 0.019
taxis GO:0042330 304 0.019
meiotic nuclear division GO:0007126 151 0.018
regulation of cell cycle GO:0051726 291 0.018
positive regulation of cellular amino acid metabolic process GO:0045764 0 0.018
oocyte development GO:0048599 124 0.018
nucleoside phosphate metabolic process GO:0006753 162 0.018
Rat Fly
muscle organ development GO:0007517 127 0.018
respiratory system development GO:0060541 213 0.018
protein dna complex subunit organization GO:0071824 86 0.018
regulation of purine nucleotide catabolic process GO:0033121 48 0.018
Rat Fly
cellular response to chemical stimulus GO:0070887 199 0.018
regulation of establishment of protein localization GO:0070201 61 0.018
peptidyl tyrosine modification GO:0018212 24 0.017
embryonic pattern specification GO:0009880 174 0.017
protein phosphorylation GO:0006468 169 0.017
transcription from rna polymerase ii promoter GO:0006366 368 0.017
single organism behavior GO:0044708 391 0.017
Mouse
meiotic dna double strand break formation GO:0042138 1 0.016
protein complex biogenesis GO:0070271 201 0.016
cytokinesis GO:0000910 90 0.016
eggshell formation GO:0030703 105 0.016
cellular component assembly involved in morphogenesis GO:0010927 151 0.016
regulation of nucleotide catabolic process GO:0030811 48 0.016
Rat Fly
hematopoietic progenitor cell differentiation GO:0002244 1 0.016
protein localization to nucleus GO:0034504 55 0.016
positive regulation of organelle organization GO:0010638 65 0.016
heterocycle catabolic process GO:0046700 166 0.016
Rat Fly
apoptotic signaling pathway GO:0097190 27 0.016
regulation of cell division GO:0051302 72 0.016
metal ion transport GO:0030001 74 0.015
positive regulation of purine nucleotide catabolic process GO:0033123 46 0.015
Rat Fly
epithelium migration GO:0090132 148 0.015
modification dependent protein catabolic process GO:0019941 78 0.015
nucleoside catabolic process GO:0009164 112 0.015
Rat Fly
regulation of multicellular organismal development GO:2000026 414 0.015
hindgut development GO:0061525 58 0.015
response to organic cyclic compound GO:0014070 89 0.015
terminal button organization GO:0072553 19 0.015
circulatory system development GO:0072359 82 0.015
negative regulation of phosphorus metabolic process GO:0010563 45 0.015
regulation of response to dna damage stimulus GO:2001020 23 0.015
tissue death GO:0016271 102 0.014
cellular response to extracellular stimulus GO:0031668 64 0.014
regulation of ras gtpase activity GO:0032318 38 0.014
response to oxidative stress GO:0006979 86 0.014
tissue migration GO:0090130 155 0.014
regulation of nucleoside metabolic process GO:0009118 50 0.014
Rat Fly
response to extracellular stimulus GO:0009991 116 0.014
regulation of meiosis GO:0040020 3 0.014
positive regulation of protein modification process GO:0031401 58 0.014
somatic stem cell division GO:0048103 37 0.013
nucleoside triphosphate catabolic process GO:0009143 108 0.013
Rat Fly
regulation of vesicle mediated transport GO:0060627 59 0.013
anterior posterior axis specification embryo GO:0008595 103 0.013
guanosine containing compound metabolic process GO:1901068 74 0.013
Rat Fly
chorion containing eggshell formation GO:0007304 105 0.013
dendrite development GO:0016358 204 0.013
negative regulation of cell communication GO:0010648 223 0.013
sister chromatid segregation GO:0000819 92 0.013
urogenital system development GO:0001655 72 0.013
actin cytoskeleton organization GO:0030036 206 0.013
protein modification by small protein conjugation GO:0032446 79 0.013
gland morphogenesis GO:0022612 145 0.012
ubiquitin dependent protein catabolic process GO:0006511 78 0.012
maintenance of location GO:0051235 73 0.012
positive regulation of biosynthetic process GO:0009891 316 0.012
autophagic cell death GO:0048102 83 0.012
regulation of wnt signaling pathway GO:0030111 68 0.012
regulation of cellular response to stress GO:0080135 89 0.012
regulation of proteolysis GO:0030162 87 0.012
posttranscriptional regulation of gene expression GO:0010608 145 0.012
negative regulation of phosphorylation GO:0042326 35 0.012
positive regulation of ras protein signal transduction GO:0046579 43 0.012
apoptotic process GO:0006915 159 0.012
negative regulation of nitrogen compound metabolic process GO:0051172 265 0.012
negative regulation of developmental process GO:0051093 201 0.011
endosomal transport GO:0016197 44 0.011
cellular component disassembly GO:0022411 46 0.011
regulation of mitotic cell cycle GO:0007346 190 0.011
positive regulation of gene expression GO:0010628 290 0.011
morphogenesis of a branching structure GO:0001763 45 0.011
protein catabolic process GO:0030163 101 0.011
regulation of nuclear division GO:0051783 58 0.011
imaginal disc derived appendage morphogenesis GO:0035114 395 0.011
cellular macromolecular complex assembly GO:0034622 153 0.011
organophosphate catabolic process GO:0046434 112 0.011
Rat Fly
protein import GO:0017038 55 0.011
branch fusion open tracheal system GO:0035147 17 0.010
regulation of alternative mrna splicing via spliceosome GO:0000381 60 0.010
stem cell differentiation GO:0048863 117 0.010
regulation of intracellular protein transport GO:0033157 46 0.010
retina development in camera type eye GO:0060041 4 0.010
extrinsic apoptotic signaling pathway GO:0097191 1 0.010
positive regulation of protein localization to nucleus GO:1900182 21 0.010
positive regulation of rna metabolic process GO:0051254 271 0.010
regulation of purine nucleotide metabolic process GO:1900542 62 0.010
Rat Fly
gliogenesis GO:0042063 80 0.010
single organismal cell cell adhesion GO:0016337 45 0.010

Git disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.035
nervous system disease DOID:863 0 0.034