Drosophila melanogaster

81 known processes

gcm2 (Dmel_CG3858)

CG3858 gene product from transcript CG3858-RA

(Aliases: CG3858,Gcm2,Dmel\CG3858,dGCM2)

gcm2 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
dendrite morphogenesis GO:0048813 199 0.385
dendrite development GO:0016358 204 0.383
forebrain development GO:0030900 2 0.184
central nervous system development GO:0007417 201 0.160
Mouse
transcription from rna polymerase ii promoter GO:0006366 368 0.154
Mouse Fly
positive regulation of transcription dna templated GO:0045893 266 0.142
Mouse Fly
negative regulation of cell differentiation GO:0045596 143 0.142
negative regulation of developmental process GO:0051093 201 0.117
stem cell development GO:0048864 79 0.108
positive regulation of rna biosynthetic process GO:1902680 266 0.100
Mouse Fly
tube morphogenesis GO:0035239 191 0.099
negative regulation of cellular metabolic process GO:0031324 382 0.089
negative regulation of cellular macromolecule biosynthetic process GO:2000113 267 0.087
negative regulation of cell communication GO:0010648 223 0.076
spindle organization GO:0007051 253 0.074
synaptic transmission GO:0007268 288 0.073
response to organic substance GO:0010033 284 0.066
Mouse
regulation of cell morphogenesis involved in differentiation GO:0010769 61 0.065
oxoacid metabolic process GO:0043436 103 0.064
regulation of localization GO:0032879 275 0.064
regulation of multicellular organismal development GO:2000026 414 0.063
Fly
regionalization GO:0003002 416 0.060
Fly
mitotic spindle organization GO:0007052 220 0.059
positive regulation of gene expression GO:0010628 290 0.058
Mouse Fly
stem cell differentiation GO:0048863 117 0.055
negative regulation of rna metabolic process GO:0051253 251 0.055
negative regulation of cellular biosynthetic process GO:0031327 277 0.055
axon guidance GO:0007411 233 0.054
Fly
negative regulation of signaling GO:0023057 219 0.053
regulation of cell morphogenesis GO:0022604 163 0.053
negative regulation of rna biosynthetic process GO:1902679 240 0.051
mesenchymal cell development GO:0014031 1 0.050
positive regulation of transcription from rna polymerase ii promoter GO:0045944 204 0.049
Mouse Fly
positive regulation of nucleic acid templated transcription GO:1903508 266 0.047
Mouse Fly
positive regulation of rna metabolic process GO:0051254 271 0.046
Mouse Fly
regulation of cell development GO:0060284 215 0.046
Fly
development of primary female sexual characteristics GO:0046545 12 0.044
response to lipopolysaccharide GO:0032496 4 0.043
negative regulation of nucleic acid templated transcription GO:1903507 240 0.043
negative regulation of macromolecule biosynthetic process GO:0010558 270 0.042
positive regulation of biosynthetic process GO:0009891 316 0.042
Mouse Fly
neuron projection guidance GO:0097485 241 0.041
Fly
morphogenesis of an epithelium GO:0002009 276 0.040
Mouse
cell division GO:0051301 248 0.040
negative regulation of cell development GO:0010721 62 0.039
cellular response to chemical stimulus GO:0070887 199 0.038
Mouse
columnar cuboidal epithelial cell development GO:0002066 249 0.037
negative regulation of transcription from rna polymerase ii promoter GO:0000122 119 0.036
mesenchymal cell differentiation GO:0048762 1 0.036
response to abiotic stimulus GO:0009628 341 0.036
epithelial tube morphogenesis GO:0060562 88 0.036
tissue morphogenesis GO:0048729 297 0.036
Mouse
regulation of anatomical structure morphogenesis GO:0022603 242 0.035
Mouse
carboxylic acid metabolic process GO:0019752 92 0.034
negative regulation of multicellular organismal process GO:0051241 142 0.034
mitotic nuclear division GO:0007067 213 0.034
regulation of transcription from rna polymerase ii promoter GO:0006357 378 0.033
Mouse Fly
regulation of cellular component movement GO:0051270 42 0.033
appendage morphogenesis GO:0035107 397 0.033
enzyme linked receptor protein signaling pathway GO:0007167 179 0.032
compound eye development GO:0048749 307 0.032
organic acid metabolic process GO:0006082 103 0.031
negative regulation of nitrogen compound metabolic process GO:0051172 265 0.031
cell proliferation GO:0008283 299 0.031
tube development GO:0035295 244 0.030
nuclear division GO:0000280 332 0.030
protein catabolic process GO:0030163 101 0.030
cell cell signaling involved in cell fate commitment GO:0045168 210 0.030
vesicle mediated transport GO:0016192 381 0.030
negative regulation of cellular component organization GO:0051129 108 0.029
rna processing GO:0006396 147 0.028
gland development GO:0048732 191 0.027
negative regulation of gene expression GO:0010629 387 0.026
segmentation GO:0035282 207 0.026
Fly
organelle fission GO:0048285 340 0.026
organic substance catabolic process GO:1901575 308 0.026
heterocycle catabolic process GO:0046700 166 0.026
chaeta development GO:0022416 97 0.026
catabolic process GO:0009056 409 0.026
negative regulation of transcription dna templated GO:0045892 237 0.026
respiratory system development GO:0060541 213 0.025
connective tissue development GO:0061448 3 0.025
Zebrafish
response to other organism GO:0051707 293 0.025
organic cyclic compound catabolic process GO:1901361 168 0.025
positive regulation of cellular biosynthetic process GO:0031328 316 0.025
Mouse Fly
epithelial cell differentiation GO:0030855 322 0.024
Zebrafish
positive regulation of nitrogen compound metabolic process GO:0051173 354 0.024
Mouse Fly
sensory organ morphogenesis GO:0090596 260 0.024
cellular protein modification process GO:0006464 438 0.024
somatic muscle development GO:0007525 66 0.023
positive regulation of cell communication GO:0010647 250 0.023
regulation of cellular ketone metabolic process GO:0010565 3 0.023
regulation of neuron differentiation GO:0045664 103 0.023
blood circulation GO:0008015 26 0.023
single organism behavior GO:0044708 391 0.022
muscle structure development GO:0061061 224 0.022
aromatic compound catabolic process GO:0019439 166 0.022
response to monosaccharide GO:0034284 4 0.022
endocytosis GO:0006897 310 0.022
neuron fate commitment GO:0048663 50 0.021
multi organism behavior GO:0051705 175 0.021
eye photoreceptor cell development GO:0042462 81 0.021
lipid modification GO:0030258 24 0.021
protein modification process GO:0036211 438 0.021
nitrogen compound transport GO:0071705 85 0.021
appendage development GO:0048736 401 0.020
death GO:0016265 284 0.020
Mouse
neuroblast proliferation GO:0007405 74 0.020
imaginal disc derived appendage development GO:0048737 399 0.020
imaginal disc derived leg morphogenesis GO:0007480 80 0.020
ribose phosphate metabolic process GO:0019693 145 0.020
wound healing GO:0042060 75 0.020
head development GO:0060322 135 0.019
Fly
cellular catabolic process GO:0044248 372 0.019
regulation of notch signaling pathway GO:0008593 100 0.019
purine ribonucleotide metabolic process GO:0009150 145 0.019
embryo development ending in birth or egg hatching GO:0009792 152 0.019
Mouse
establishment of localization in cell GO:0051649 402 0.019
feeding behavior GO:0007631 50 0.019
cellular macromolecule localization GO:0070727 220 0.019
negative regulation of nucleobase containing compound metabolic process GO:0045934 261 0.018
chemotaxis GO:0006935 249 0.018
Fly
imaginal disc pattern formation GO:0007447 91 0.018
branching morphogenesis of an epithelial tube GO:0048754 45 0.018
cell fate specification GO:0001708 71 0.018
Zebrafish
chorion containing eggshell formation GO:0007304 105 0.018
embryonic pattern specification GO:0009880 174 0.018
Fly
purine containing compound catabolic process GO:0072523 112 0.018
eye photoreceptor cell differentiation GO:0001754 145 0.018
small molecule metabolic process GO:0044281 305 0.018
photoreceptor cell development GO:0042461 96 0.018
kidney morphogenesis GO:0060993 3 0.018
post embryonic appendage morphogenesis GO:0035120 385 0.018
anterior posterior axis specification GO:0009948 109 0.018
purine ribonucleoside metabolic process GO:0046128 127 0.017
cell motility GO:0048870 251 0.017
cellular nitrogen compound catabolic process GO:0044270 165 0.017
ribonucleoside catabolic process GO:0042454 112 0.017
spermatogenesis GO:0007283 200 0.017
atp metabolic process GO:0046034 49 0.017
mrna metabolic process GO:0016071 124 0.017
negative regulation of nervous system development GO:0051961 92 0.017
chromosome organization GO:0051276 360 0.017
anterior posterior pattern specification GO:0009952 136 0.017
morphogenesis of a branching structure GO:0001763 45 0.017
Mouse
regulation of epithelial cell differentiation GO:0030856 4 0.017
phagocytosis GO:0006909 215 0.017
regulation of cell differentiation GO:0045595 302 0.016
compound eye photoreceptor cell differentiation GO:0001751 140 0.016
regulation of neurogenesis GO:0050767 158 0.016
Fly
regulation of nervous system development GO:0051960 248 0.016
Fly
centrosome duplication GO:0051298 121 0.016
response to external biotic stimulus GO:0043207 293 0.016
negative regulation of response to stimulus GO:0048585 258 0.016
taxis GO:0042330 304 0.016
Fly
salivary gland development GO:0007431 162 0.016
purine nucleotide catabolic process GO:0006195 109 0.015
cell migration GO:0016477 238 0.015
wing disc morphogenesis GO:0007472 344 0.015
stem cell proliferation GO:0072089 88 0.015
muscle organ development GO:0007517 127 0.015
regulation of mitotic cell cycle phase transition GO:1901990 130 0.015
response to osmotic stress GO:0006970 14 0.015
monocarboxylic acid transport GO:0015718 3 0.015
ribonucleoside triphosphate catabolic process GO:0009203 108 0.015
morphogenesis of a branching epithelium GO:0061138 45 0.015
Mouse
cellular response to organic substance GO:0071310 132 0.015
Mouse
regulation of cell proliferation GO:0042127 163 0.015
Fly
positive regulation of cellular component organization GO:0051130 156 0.014
Mouse
response to ethanol GO:0045471 59 0.014
ribonucleotide catabolic process GO:0009261 109 0.014
developmental maturation GO:0021700 172 0.014
embryonic development via the syncytial blastoderm GO:0001700 148 0.014
humoral immune response GO:0006959 117 0.014
nephron development GO:0072006 3 0.014
leg disc development GO:0035218 92 0.014
body morphogenesis GO:0010171 2 0.014
syncytium formation GO:0006949 43 0.014
Mouse
regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090092 38 0.014
kidney epithelium development GO:0072073 3 0.014
single organism intracellular transport GO:1902582 207 0.014
regulation of transport GO:0051049 181 0.013
regulation of mitosis GO:0007088 56 0.013
compound eye photoreceptor development GO:0042051 78 0.013
organelle assembly GO:0070925 198 0.013
imaginal disc derived wing morphogenesis GO:0007476 337 0.013
regulation of mitotic cell cycle GO:0007346 190 0.013
positive regulation of neurogenesis GO:0050769 41 0.013
Fly
nucleoside metabolic process GO:0009116 127 0.013
reproductive system development GO:0061458 74 0.013
Mouse
single organism catabolic process GO:0044712 228 0.013
cell fate determination GO:0001709 91 0.013
Fly
embryonic axis specification GO:0000578 107 0.013
nucleobase containing small molecule metabolic process GO:0055086 174 0.013
macromolecular complex assembly GO:0065003 256 0.013
epithelial cell development GO:0002064 274 0.013
regulation of programmed cell death GO:0043067 152 0.012
Mouse
regulation of cellular amino acid metabolic process GO:0006521 0 0.012
regulation of cellular localization GO:0060341 136 0.012
purine ribonucleotide catabolic process GO:0009154 109 0.012
regulation of nuclear division GO:0051783 58 0.012
positive regulation of cell differentiation GO:0045597 64 0.012
Fly
negative regulation of biosynthetic process GO:0009890 277 0.012
regulation of neural precursor cell proliferation GO:2000177 35 0.012
positive regulation of cellular amino acid metabolic process GO:0045764 0 0.012
intracellular mrna localization GO:0008298 66 0.012
blastoderm segmentation GO:0007350 159 0.012
Fly
compound eye morphogenesis GO:0001745 249 0.012
regulation of embryonic development GO:0045995 68 0.012
tripartite regional subdivision GO:0007351 103 0.012
ribonucleoside triphosphate metabolic process GO:0009199 119 0.012
columnar cuboidal epithelial cell differentiation GO:0002065 256 0.012
negative regulation of cell cycle process GO:0010948 109 0.012
response to salt stress GO:0009651 11 0.011
neural precursor cell proliferation GO:0061351 75 0.011
intracellular protein transport GO:0006886 104 0.011
regulation of cell death GO:0010941 173 0.011
Mouse
organic substance transport GO:0071702 257 0.011
positive regulation of macromolecule biosynthetic process GO:0010557 283 0.011
Mouse Fly
ribonucleoside metabolic process GO:0009119 127 0.011
hemocyte differentiation GO:0042386 38 0.011
salivary gland morphogenesis GO:0007435 145 0.011
ubiquitin dependent protein catabolic process GO:0006511 78 0.011
imaginal disc derived appendage morphogenesis GO:0035114 395 0.011
ribonucleoside monophosphate catabolic process GO:0009158 39 0.011
spinal cord development GO:0021510 1 0.011
benzene containing compound metabolic process GO:0042537 3 0.011
glial cell fate commitment GO:0021781 3 0.011
Mouse Fly
hematopoietic progenitor cell differentiation GO:0002244 1 0.011
organonitrogen compound catabolic process GO:1901565 128 0.011
dorsal ventral pattern formation GO:0009953 133 0.011
eye morphogenesis GO:0048592 260 0.011
regulation of cell cycle GO:0051726 291 0.011
negative regulation of signal transduction GO:0009968 206 0.011
digestive tract development GO:0048565 149 0.011
protein localization GO:0008104 284 0.011
protein complex biogenesis GO:0070271 201 0.011
regulation of organ morphogenesis GO:2000027 78 0.011
female sex differentiation GO:0046660 20 0.011
protein dna complex subunit organization GO:0071824 86 0.011
nephron tubule development GO:0072080 3 0.011
nucleoside catabolic process GO:0009164 112 0.011
dorsal ventral pattern formation imaginal disc GO:0007450 51 0.011
regulation of cell cycle phase transition GO:1901987 130 0.011
purine containing compound metabolic process GO:0072521 155 0.011
regulation of reproductive process GO:2000241 54 0.011
transmembrane transport GO:0055085 139 0.010
camera type eye morphogenesis GO:0048593 2 0.010
segment polarity determination GO:0007367 25 0.010
regulation of cell motility GO:2000145 23 0.010
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 65 0.010
organonitrogen compound metabolic process GO:1901564 318 0.010
positive regulation of cell death GO:0010942 69 0.010
purine ribonucleoside catabolic process GO:0046130 112 0.010
neuromuscular synaptic transmission GO:0007274 67 0.010
regulation of cell division GO:0051302 72 0.010
rrna processing GO:0006364 3 0.010
ion transmembrane transport GO:0034220 122 0.010
morphogenesis of embryonic epithelium GO:0016331 94 0.010
protein complex assembly GO:0006461 200 0.010
purine nucleoside monophosphate metabolic process GO:0009126 50 0.010
glycosyl compound catabolic process GO:1901658 112 0.010
outflow tract morphogenesis GO:0003151 4 0.010
wing disc pattern formation GO:0035222 66 0.010
very long chain fatty acid metabolic process GO:0000038 4 0.010

gcm2 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.033
disease of metabolism DOID:0014667 0 0.022
inherited metabolic disorder DOID:655 0 0.022
cardiovascular system disease DOID:1287 0 0.017
cancer DOID:162 0 0.016
disease of cellular proliferation DOID:14566 0 0.016
organ system cancer DOID:0050686 0 0.012
nervous system disease DOID:863 0 0.011