Drosophila melanogaster

161 known processes

spin (Dmel_CG8428)

spinster

(Aliases: CG8428,l(2R)W5,l(2)W5,l(2)k02511,25/11,Dmel\CG8428,l(2)k09905,Spin,bnch,l(2)10403)

spin biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
determination of adult lifespan GO:0008340 137 0.807
protein localization GO:0008104 284 0.777
intracellular transport GO:0046907 228 0.684
oocyte development GO:0048599 124 0.634
oocyte differentiation GO:0009994 145 0.626
phosphorylation GO:0016310 294 0.565
positive regulation of catabolic process GO:0009896 105 0.552
regulation of autophagy GO:0010506 62 0.549
positive regulation of nitrogen compound metabolic process GO:0051173 354 0.497
regulation of catabolic process GO:0009894 170 0.492
membrane organization GO:0061024 112 0.485
autophagy GO:0006914 108 0.483
positive regulation of autophagy GO:0010508 21 0.456
death GO:0016265 284 0.451
cell motility GO:0048870 251 0.444
cellular component assembly involved in morphogenesis GO:0010927 151 0.409
single organism behavior GO:0044708 391 0.397
multicellular organismal aging GO:0010259 140 0.393
single organism intracellular transport GO:1902582 207 0.371
macroautophagy GO:0016236 42 0.366
synapse organization GO:0050808 196 0.356
cell death GO:0008219 279 0.355
cellular lipid metabolic process GO:0044255 83 0.347
lipid modification GO:0030258 24 0.328
regulation of cell cycle GO:0051726 291 0.318
single organism membrane fusion GO:0044801 42 0.308
response to radiation GO:0009314 155 0.304
protein modification process GO:0036211 438 0.298
regulation of cellular catabolic process GO:0031329 157 0.285
positive regulation of macroautophagy GO:0016239 8 0.275
response to extracellular stimulus GO:0009991 116 0.271
pole plasm oskar mrna localization GO:0045451 46 0.267
pole plasm mrna localization GO:0019094 49 0.261
catabolic process GO:0009056 409 0.240
positive regulation of response to extracellular stimulus GO:0032106 8 0.229
pole plasm rna localization GO:0007316 52 0.227
neuromuscular synaptic transmission GO:0007274 67 0.217
programmed cell death GO:0012501 257 0.212
synaptic transmission GO:0007268 288 0.204
cell proliferation GO:0008283 299 0.200
establishment of localization in cell GO:0051649 402 0.196
developmental maturation GO:0021700 172 0.184
regulation of cellular response to stress GO:0080135 89 0.180
oocyte anterior posterior axis specification GO:0007314 72 0.180
lipid metabolic process GO:0006629 121 0.172
regulation of response to stress GO:0080134 200 0.167
regulation of phosphorus metabolic process GO:0051174 210 0.165
cellular response to nutrient levels GO:0031669 62 0.164
embryonic pattern specification GO:0009880 174 0.152
membrane fusion GO:0061025 42 0.152
synapse assembly GO:0007416 143 0.143
single organism membrane organization GO:0044802 93 0.142
regulation of phosphate metabolic process GO:0019220 210 0.142
positive regulation of nucleic acid templated transcription GO:1903508 266 0.139
pole plasm assembly GO:0007315 61 0.133
vesicle mediated transport GO:0016192 381 0.132
synaptic vesicle transport GO:0048489 50 0.128
cytoplasmic transport nurse cell to oocyte GO:0007303 12 0.126
oocyte axis specification GO:0007309 108 0.126
regulation of protein metabolic process GO:0051246 256 0.123
oocyte construction GO:0007308 112 0.122
aging GO:0007568 143 0.121
positive regulation of macromolecule biosynthetic process GO:0010557 283 0.121
regulation of phosphorylation GO:0042325 147 0.120
cellular macromolecule localization GO:0070727 220 0.117
positive regulation of macromolecule metabolic process GO:0010604 405 0.116
digestive tract development GO:0048565 149 0.114
positive regulation of cellular catabolic process GO:0031331 95 0.114
neurological system process GO:0050877 358 0.113
gliogenesis GO:0042063 80 0.113
organelle fusion GO:0048284 46 0.108
peptidyl amino acid modification GO:0018193 105 0.107
regulation of apoptotic process GO:0042981 130 0.104
vesicle localization GO:0051648 55 0.104
embryo development ending in birth or egg hatching GO:0009792 152 0.102
Zebrafish Worm
intracellular signal transduction GO:0035556 300 0.102
blastoderm segmentation GO:0007350 159 0.096
enzyme linked receptor protein signaling pathway GO:0007167 179 0.095
cognition GO:0050890 141 0.094
regulation of nurse cell apoptotic process GO:0045477 9 0.093
detection of external stimulus GO:0009581 66 0.090
positive regulation of transcription dna templated GO:0045893 266 0.090
apoptotic process involved in development GO:1902742 20 0.089
chromatin remodeling GO:0006338 72 0.088
hindgut development GO:0061525 58 0.086
tripartite regional subdivision GO:0007351 103 0.086
post embryonic appendage morphogenesis GO:0035120 385 0.085
positive regulation of biosynthetic process GO:0009891 316 0.084
protein targeting GO:0006605 64 0.082
embryonic axis specification GO:0000578 107 0.081
cytoskeleton dependent intracellular transport GO:0030705 44 0.081
learning or memory GO:0007611 141 0.080
positive regulation of nucleobase containing compound metabolic process GO:0045935 332 0.080
oocyte microtubule cytoskeleton polarization GO:0008103 22 0.080
lipid storage GO:0019915 38 0.080
regulation of cell development GO:0060284 215 0.080
regulation of multicellular organismal development GO:2000026 414 0.079
cellular response to extracellular stimulus GO:0031668 64 0.079
imaginal disc derived appendage morphogenesis GO:0035114 395 0.077
germarium derived oocyte fate determination GO:0007294 26 0.076
regulation of proteolysis GO:0030162 87 0.076
tissue homeostasis GO:0001894 36 0.075
posttranscriptional regulation of gene expression GO:0010608 145 0.074
nurse cell apoptotic process GO:0045476 17 0.073
cellular response to starvation GO:0009267 61 0.073
cellular response to external stimulus GO:0071496 66 0.073
neuron neuron synaptic transmission GO:0007270 14 0.073
cellular catabolic process GO:0044248 372 0.073
appendage morphogenesis GO:0035107 397 0.071
cell type specific apoptotic process GO:0097285 38 0.071
regulation of cellular protein metabolic process GO:0032268 243 0.068
ovarian follicle cell development GO:0030707 248 0.066
regulation of catalytic activity GO:0050790 185 0.065
positive regulation of gene expression GO:0010628 290 0.065
regulation of response to nutrient levels GO:0032107 18 0.065
cell maturation GO:0048469 144 0.064
positive regulation of response to external stimulus GO:0032103 44 0.064
eye development GO:0001654 323 0.064
regulation of synapse organization GO:0050807 110 0.061
vesicle fusion GO:0006906 19 0.059
imaginal disc derived appendage development GO:0048737 399 0.058
organelle assembly GO:0070925 198 0.057
organic substance transport GO:0071702 257 0.057
regulation of transport GO:0051049 181 0.056
negative regulation of neuron death GO:1901215 18 0.055
macromolecule catabolic process GO:0009057 161 0.055
positive regulation of cellular component organization GO:0051130 156 0.054
compound eye development GO:0048749 307 0.053
glycerolipid metabolic process GO:0046486 34 0.053
positive regulation of cellular amino acid metabolic process GO:0045764 0 0.053
intracellular mrna localization involved in pattern specification process GO:0060810 56 0.052
locomotory behavior GO:0007626 176 0.051
anterior posterior pattern specification GO:0009952 136 0.051
protein modification by small protein conjugation GO:0032446 79 0.051
response to abiotic stimulus GO:0009628 341 0.050
positive regulation of rna metabolic process GO:0051254 271 0.049
response to starvation GO:0042594 97 0.048
regulation of cellular amino acid metabolic process GO:0006521 0 0.048
positive regulation of rna biosynthetic process GO:1902680 266 0.047
regulation of molecular function GO:0065009 217 0.046
positive regulation of proteolysis GO:0045862 52 0.045
intrinsic apoptotic signaling pathway in response to dna damage GO:0008630 11 0.045
amine metabolic process GO:0009308 12 0.045
apoptotic process GO:0006915 159 0.045
ovarian follicle cell migration GO:0007297 121 0.044
organic substance catabolic process GO:1901575 308 0.044
protein phosphorylation GO:0006468 169 0.043
organonitrogen compound metabolic process GO:1901564 318 0.043
wing disc morphogenesis GO:0007472 344 0.042
synaptic growth at neuromuscular junction GO:0051124 119 0.042
regulation of multi organism process GO:0043900 131 0.042
phagocytosis GO:0006909 215 0.041
axon development GO:0061564 297 0.041
maternal determination of anterior posterior axis embryo GO:0008358 74 0.040
single organism cellular localization GO:1902580 180 0.040
cellular amino acid metabolic process GO:0006520 61 0.040
regulation of protein phosphorylation GO:0001932 64 0.040
negative regulation of programmed cell death GO:0043069 72 0.040
negative regulation of kinase activity GO:0033673 16 0.039
regulation of hydrolase activity GO:0051336 97 0.039
cilium assembly GO:0042384 38 0.039
endocytosis GO:0006897 310 0.038
intrinsic apoptotic signaling pathway GO:0097193 16 0.038
anatomical structure homeostasis GO:0060249 97 0.038
cellular protein modification process GO:0006464 438 0.036
regulation of phosphatase activity GO:0010921 3 0.036
bmp signaling pathway GO:0030509 27 0.036
regulation of macroautophagy GO:0016241 15 0.036
organelle membrane fusion GO:0090174 16 0.035
adult behavior GO:0030534 137 0.034
epithelium migration GO:0090132 148 0.033
response to oxygen containing compound GO:1901700 200 0.033
epithelial cell morphogenesis involved in gastrulation GO:0003381 7 0.033
central nervous system development GO:0007417 201 0.032
appendage development GO:0048736 401 0.032
tissue migration GO:0090130 155 0.031
anterior posterior axis specification GO:0009948 109 0.031
organophosphate metabolic process GO:0019637 195 0.031
microtubule based transport GO:0010970 42 0.031
regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090092 38 0.030
positive regulation of molecular function GO:0044093 136 0.030
necrotic cell death GO:0070265 1 0.029
anterior posterior axis specification embryo GO:0008595 103 0.029
developmental growth GO:0048589 280 0.029
modification dependent macromolecule catabolic process GO:0043632 79 0.029
negative regulation of signaling GO:0023057 219 0.029
spindle organization GO:0007051 253 0.029
regulation of establishment of protein localization GO:0070201 61 0.029
regulation of cellular localization GO:0060341 136 0.028
regulation of response to external stimulus GO:0032101 115 0.028
establishment or maintenance of polarity of follicular epithelium GO:0016334 26 0.028
regulation of synaptic transmission GO:0050804 69 0.028
regulation of cell cycle process GO:0010564 181 0.028
signal transduction by phosphorylation GO:0023014 107 0.027
regulation of protein modification process GO:0031399 112 0.027
regulation of neuron death GO:1901214 26 0.027
positive regulation of response to stimulus GO:0048584 323 0.027
border follicle cell migration GO:0007298 113 0.027
histolysis GO:0007559 102 0.026
positive regulation of cell communication GO:0010647 250 0.026
cellular amine metabolic process GO:0044106 12 0.025
regulation of necrotic cell death GO:0010939 1 0.025
ribonucleotide catabolic process GO:0009261 109 0.025
apoptotic signaling pathway GO:0097190 27 0.025
mitochondrion transport along microtubule GO:0047497 5 0.025
cytoplasmic transport GO:0016482 130 0.025
regulation of embryonic development GO:0045995 68 0.025
mapk cascade GO:0000165 107 0.024
axis specification GO:0009798 167 0.024
positive regulation of signal transduction GO:0009967 223 0.024
regulation of response to oxidative stress GO:1902882 4 0.024
chromatin modification GO:0016568 147 0.024
epithelial cell development GO:0002064 274 0.024
columnar cuboidal epithelial cell differentiation GO:0002065 256 0.024
cortical cytoskeleton organization GO:0030865 29 0.023
cell migration GO:0016477 238 0.023
positive regulation of protein metabolic process GO:0051247 128 0.023
response to heat GO:0009408 63 0.022
organelle localization GO:0051640 148 0.022
cellular response to chemical stimulus GO:0070887 199 0.022
negative regulation of neuron apoptotic process GO:0043524 14 0.022
morphogenesis of embryonic epithelium GO:0016331 94 0.022
cellular macromolecule catabolic process GO:0044265 136 0.021
protein transport GO:0015031 155 0.021
anterograde axon cargo transport GO:0008089 6 0.021
exocytosis GO:0006887 28 0.021
short term memory GO:0007614 19 0.021
organic cyclic compound catabolic process GO:1901361 168 0.021
regulation of synapse assembly GO:0051963 94 0.021
connective tissue development GO:0061448 3 0.021
Zebrafish
detection of abiotic stimulus GO:0009582 66 0.020
oocyte microtubule cytoskeleton organization GO:0016325 35 0.020
cation transport GO:0006812 110 0.020
extrinsic apoptotic signaling pathway GO:0097191 1 0.020
oxoacid metabolic process GO:0043436 103 0.020
regulation of cell death GO:0010941 173 0.020
neuron apoptotic process GO:0051402 17 0.020
substrate dependent cell migration GO:0006929 3 0.020
small gtpase mediated signal transduction GO:0007264 88 0.020
regulation of embryonic pattern specification GO:1902875 27 0.020
developmental programmed cell death GO:0010623 138 0.020
regulation of pole plasm oskar mrna localization GO:0007317 27 0.020
actin filament organization GO:0007015 126 0.019
positive regulation of cell differentiation GO:0045597 64 0.019
stem cell division GO:0017145 69 0.019
maintenance of location GO:0051235 73 0.019
regulation of programmed cell death GO:0043067 152 0.019
regulation of lipid storage GO:0010883 22 0.018
segmentation GO:0035282 207 0.018
purine ribonucleoside triphosphate metabolic process GO:0009205 119 0.018
cell cycle arrest GO:0007050 4 0.018
positive regulation of organelle organization GO:0010638 65 0.018
positive regulation of cell death GO:0010942 69 0.018
epidermal growth factor receptor signaling pathway GO:0007173 58 0.018
carboxylic acid metabolic process GO:0019752 92 0.017
negative regulation of lipid storage GO:0010888 3 0.017
dorsal closure GO:0007391 79 0.017
positive regulation of apoptotic process GO:0043065 47 0.017
negative regulation of synaptic growth at neuromuscular junction GO:0045886 39 0.017
establishment of protein localization GO:0045184 163 0.017
wing disc pattern formation GO:0035222 66 0.017
ribonucleoside triphosphate catabolic process GO:0009203 108 0.017
negative regulation of apoptotic process GO:0043066 63 0.017
regulation of protein localization GO:0032880 76 0.017
response to ethanol GO:0045471 59 0.017
regulation of synapse structure and activity GO:0050803 128 0.017
positive regulation of phosphorylation GO:0042327 87 0.016
chorion containing eggshell formation GO:0007304 105 0.016
purine containing compound catabolic process GO:0072523 112 0.016
chemosensory behavior GO:0007635 106 0.016
dorsal ventral axis specification ovarian follicular epithelium GO:0008069 13 0.016
regulation of cellular ketone metabolic process GO:0010565 3 0.016
regulation of erbb signaling pathway GO:1901184 42 0.016
heterocycle catabolic process GO:0046700 166 0.016
embryonic organ development GO:0048568 50 0.016
Zebrafish
developmental cell growth GO:0048588 52 0.016
ameboidal type cell migration GO:0001667 151 0.016
digestive tract morphogenesis GO:0048546 127 0.016
cilium organization GO:0044782 41 0.016
cellular nitrogen compound catabolic process GO:0044270 165 0.015
regulation of protein transport GO:0051223 57 0.015
gene silencing by mirna GO:0035195 22 0.015
negative regulation of phosphorylation GO:0042326 35 0.015
vesicle organization GO:0016050 44 0.015
gastrulation GO:0007369 70 0.015
protein ubiquitination GO:0016567 70 0.015
multicellular organismal homeostasis GO:0048871 41 0.015
regulation of cellular amine metabolic process GO:0033238 3 0.015
body morphogenesis GO:0010171 2 0.015
positive regulation of endopeptidase activity GO:0010950 26 0.015
ras protein signal transduction GO:0007265 88 0.015
ovarian nurse cell to oocyte transport GO:0007300 27 0.015
embryonic development via the syncytial blastoderm GO:0001700 148 0.014
regulation of nucleotide catabolic process GO:0030811 48 0.014
triglyceride metabolic process GO:0006641 12 0.014
outflow tract morphogenesis GO:0003151 4 0.014
negative regulation of cell proliferation GO:0008285 69 0.014
purine ribonucleotide catabolic process GO:0009154 109 0.014
adult locomotory behavior GO:0008344 76 0.014
regulation of nervous system development GO:0051960 248 0.014
regulation of neuron apoptotic process GO:0043523 16 0.014
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 116 0.014
transmission of nerve impulse GO:0019226 12 0.014
rna localization GO:0006403 115 0.014
intracellular mrna localization GO:0008298 66 0.014
regionalization GO:0003002 416 0.014
regulation of viral genome replication GO:0045069 4 0.013
anterior midgut ectodermal morphogenesis GO:0007441 4 0.013
cilium morphogenesis GO:0060271 39 0.013
regulation of cysteine type endopeptidase activity involved in apoptotic process GO:0043281 25 0.013
germ line cyst formation GO:0048134 44 0.013
regulation of jnk cascade GO:0046328 40 0.013
endomembrane system organization GO:0010256 119 0.013
regulation of response to extracellular stimulus GO:0032104 18 0.013
regulation of cell substrate adhesion GO:0010810 2 0.013
axonal fasciculation GO:0007413 12 0.013
protein catabolic process GO:0030163 101 0.013
actin filament based movement GO:0030048 26 0.013
cell recognition GO:0008037 102 0.013
regulation of cellular response to oxidative stress GO:1900407 4 0.013
positive regulation of hydrolase activity GO:0051345 78 0.012
urogenital system development GO:0001655 72 0.012
organic acid metabolic process GO:0006082 103 0.012
regulation of pathway restricted smad protein phosphorylation GO:0060393 1 0.012
positive regulation of intracellular signal transduction GO:1902533 116 0.012
neuron death GO:0070997 27 0.012
negative regulation of cell death GO:0060548 81 0.012
oocyte dorsal ventral axis specification GO:0007310 34 0.012
oocyte nucleus localization involved in oocyte dorsal ventral axis specification GO:0051663 12 0.012
establishment of mitochondrion localization GO:0051654 7 0.012
regulation of small gtpase mediated signal transduction GO:0051056 93 0.012
morphogenesis of follicular epithelium GO:0016333 36 0.012
glial cell differentiation GO:0010001 35 0.012
regulation of secretion by cell GO:1903530 39 0.012
response to oxidative stress GO:0006979 86 0.011
feeding behavior GO:0007631 50 0.011
regulation of lipid kinase activity GO:0043550 2 0.011
negative regulation of nervous system development GO:0051961 92 0.011
muscle contraction GO:0006936 13 0.011
synaptic vesicle recycling GO:0036465 28 0.011
positive regulation of response to nutrient levels GO:0032109 8 0.011
proteolysis GO:0006508 192 0.011
embryonic morphogenesis GO:0048598 206 0.011
Zebrafish
single organism biosynthetic process GO:0044711 206 0.011
response to wounding GO:0009611 94 0.011
regulation of localization GO:0032879 275 0.011
phospholipid metabolic process GO:0006644 23 0.011
photoreceptor cell differentiation GO:0046530 170 0.011
regulation of phosphatidylinositol 3 kinase activity GO:0043551 2 0.011
olfactory behavior GO:0042048 97 0.011
regulation of gene expression epigenetic GO:0040029 128 0.011
insulin receptor signaling pathway GO:0008286 25 0.011
cellular ketone metabolic process GO:0042180 24 0.011
establishment of protein localization to membrane GO:0090150 11 0.011
intracellular mrna localization involved in anterior posterior axis specification GO:0060811 53 0.011
single organism catabolic process GO:0044712 228 0.011
positive regulation of axon guidance GO:1902669 1 0.010
digestive system development GO:0055123 149 0.010
positive regulation of transport GO:0051050 92 0.010
regulation of kinase activity GO:0043549 53 0.010
cytoplasm organization GO:0007028 64 0.010
regulation of epithelial cell migration open tracheal system GO:2000274 11 0.010
learning GO:0007612 75 0.010
purine nucleoside metabolic process GO:0042278 127 0.010
leg disc development GO:0035218 92 0.010
imaginal disc derived leg segmentation GO:0036011 26 0.010
regulation of ras protein signal transduction GO:0046578 93 0.010
growth GO:0040007 359 0.010
germarium derived oocyte differentiation GO:0030706 29 0.010

spin disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.029
nervous system disease DOID:863 0 0.029