Drosophila melanogaster

58 known processes

Jhe (Dmel_CG8425)

Juvenile hormone esterase

(Aliases: jhe,JHE,CG8425,Dmel\CG8425,JH,DmJhe)

Jhe biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
secondary metabolite biosynthetic process GO:0044550 24 0.683
Fly
mating GO:0007618 120 0.621
secondary metabolic process GO:0019748 75 0.575
Fly
reproductive behavior GO:0019098 122 0.573
single organism behavior GO:0044708 391 0.396
response to alcohol GO:0097305 95 0.373
male mating behavior GO:0060179 70 0.334
behavioral response to ethanol GO:0048149 49 0.315
tissue migration GO:0090130 155 0.288
axon guidance GO:0007411 233 0.266
columnar cuboidal epithelial cell differentiation GO:0002065 256 0.234
axon development GO:0061564 297 0.232
response to ethanol GO:0045471 59 0.219
taxis GO:0042330 304 0.208
epithelium migration GO:0090132 148 0.186
response to insecticide GO:0017085 14 0.176
ovarian follicle cell development GO:0030707 248 0.168
ovarian follicle cell migration GO:0007297 121 0.157
hormone biosynthetic process GO:0042446 20 0.152
Fly
epithelial cell migration GO:0010631 148 0.150
imaginal disc derived appendage development GO:0048737 399 0.146
adult behavior GO:0030534 137 0.142
response to light stimulus GO:0009416 124 0.142
ethanolamine containing compound metabolic process GO:0042439 4 0.140
response to oxygen containing compound GO:1901700 200 0.135
cell migration GO:0016477 238 0.131
mating behavior GO:0007617 106 0.131
acetylcholine metabolic process GO:0008291 2 0.125
neuron projection guidance GO:0097485 241 0.120
meiotic nuclear division GO:0007126 151 0.115
response to organic substance GO:0010033 284 0.109
acetate ester metabolic process GO:1900619 2 0.108
neurotransmitter metabolic process GO:0042133 2 0.107
post embryonic appendage morphogenesis GO:0035120 385 0.103
chemotaxis GO:0006935 249 0.102
single organism biosynthetic process GO:0044711 206 0.102
Fly
regulation of anatomical structure size GO:0090066 163 0.099
defense response to other organism GO:0098542 225 0.097
pheromone biosynthetic process GO:0042811 3 0.093
Fly
epithelial cell development GO:0002064 274 0.090
response to external biotic stimulus GO:0043207 293 0.087
acetylcholine catabolic process GO:0006581 1 0.087
response to other organism GO:0051707 293 0.086
multi organism behavior GO:0051705 175 0.083
female meiotic division GO:0007143 70 0.082
neuron recognition GO:0008038 101 0.082
meiotic cell cycle GO:0051321 171 0.080
axonogenesis GO:0007409 290 0.075
response to abiotic stimulus GO:0009628 341 0.072
lauric acid metabolic process GO:0048252 1 0.071
appendage morphogenesis GO:0035107 397 0.068
regulation of tube architecture open tracheal system GO:0035152 68 0.068
choline metabolic process GO:0019695 1 0.067
neurotransmitter catabolic process GO:0042135 1 0.067
amine catabolic process GO:0009310 1 0.067
insecticide metabolic process GO:0017143 2 0.065
cellular amine metabolic process GO:0044106 12 0.062
lipid metabolic process GO:0006629 121 0.061
imaginal disc derived wing morphogenesis GO:0007476 337 0.060
response to biotic stimulus GO:0009607 294 0.060
regionalization GO:0003002 416 0.060
skin development GO:0043588 65 0.060
choline catabolic process GO:0042426 1 0.057
border follicle cell migration GO:0007298 113 0.056
imaginal disc derived appendage morphogenesis GO:0035114 395 0.055
vesicle mediated transport GO:0016192 381 0.052
wing disc morphogenesis GO:0007472 344 0.052
localization of cell GO:0051674 257 0.051
cell motility GO:0048870 251 0.051
ameboidal type cell migration GO:0001667 151 0.050
appendage development GO:0048736 401 0.050
regulation of tube size open tracheal system GO:0035151 43 0.049
organonitrogen compound metabolic process GO:1901564 318 0.049
male gamete generation GO:0048232 201 0.047
response to organophosphorus GO:0046683 2 0.046
gland development GO:0048732 191 0.045
negative regulation of cellular component organization GO:0051129 108 0.045
amine metabolic process GO:0009308 12 0.045
programmed cell death GO:0012501 257 0.044
columnar cuboidal epithelial cell development GO:0002066 249 0.043
response to radiation GO:0009314 155 0.042
meiotic chromosome segregation GO:0045132 59 0.042
aggressive behavior GO:0002118 63 0.042
response to mercury ion GO:0046689 3 0.041
cellular response to chemical stimulus GO:0070887 199 0.040
defense response GO:0006952 300 0.039
small molecule metabolic process GO:0044281 305 0.039
epithelial cell differentiation GO:0030855 322 0.038
death GO:0016265 284 0.038
open tracheal system development GO:0007424 204 0.038
steroid catabolic process GO:0006706 1 0.038
epidermis development GO:0008544 65 0.037
response to starvation GO:0042594 97 0.037
transition metal ion homeostasis GO:0055076 17 0.037
cell death GO:0008219 279 0.036
positive regulation of signaling GO:0023056 243 0.036
growth GO:0040007 359 0.036
cellular biogenic amine catabolic process GO:0042402 1 0.035
protein localization GO:0008104 284 0.035
aging GO:0007568 143 0.035
positive regulation of cell communication GO:0010647 250 0.034
transcription from rna polymerase ii promoter GO:0006366 368 0.034
nuclear division GO:0000280 332 0.034
insecticide catabolic process GO:0046701 1 0.034
respiratory system development GO:0060541 213 0.034
regulation of cell development GO:0060284 215 0.034
defense response to bacterium GO:0042742 178 0.034
regulation of multicellular organismal development GO:2000026 414 0.033
axis specification GO:0009798 167 0.033
organelle fission GO:0048285 340 0.033
secondary metabolite catabolic process GO:0090487 1 0.033
circulatory system development GO:0072359 82 0.032
regulation of neurogenesis GO:0050767 158 0.032
positive regulation of nitrogen compound metabolic process GO:0051173 354 0.032
vitamin biosynthetic process GO:0009110 1 0.032
meiotic cell cycle process GO:1903046 132 0.032
spermatid differentiation GO:0048515 114 0.032
apoptotic process GO:0006915 159 0.032
cell recognition GO:0008037 102 0.032
regulation of immune system process GO:0002682 176 0.031
dendrite morphogenesis GO:0048813 199 0.031
negative regulation of response to stimulus GO:0048585 258 0.030
biological adhesion GO:0022610 138 0.030
carboxylic acid metabolic process GO:0019752 92 0.030
xenobiotic catabolic process GO:0042178 1 0.030
negative regulation of cell communication GO:0010648 223 0.029
positive regulation of response to stimulus GO:0048584 323 0.029
multicellular organismal aging GO:0010259 140 0.029
positive regulation of macromolecule biosynthetic process GO:0010557 283 0.029
regulation of intracellular signal transduction GO:1902531 236 0.029
establishment of localization in cell GO:0051649 402 0.028
response to bacterium GO:0009617 198 0.028
negative regulation of gene expression GO:0010629 387 0.028
endocytosis GO:0006897 310 0.028
homeostatic process GO:0042592 199 0.028
phosphatidic acid metabolic process GO:0046473 1 0.028
organic hydroxy compound metabolic process GO:1901615 83 0.028
phagocytosis GO:0006909 215 0.028
establishment of blood nerve barrier GO:0008065 2 0.028
positive regulation of nucleobase containing compound metabolic process GO:0045935 332 0.028
cellular amino acid metabolic process GO:0006520 61 0.027
regulation of programmed cell death GO:0043067 152 0.027
regulation of organelle organization GO:0033043 196 0.027
single organism catabolic process GO:0044712 228 0.027
organophosphate metabolic process GO:0019637 195 0.026
cell proliferation GO:0008283 299 0.026
polyol biosynthetic process GO:0046173 3 0.025
positive regulation of macromolecule metabolic process GO:0010604 405 0.025
regulation of transcription from rna polymerase ii promoter GO:0006357 378 0.025
motor neuron axon guidance GO:0008045 58 0.025
oxoacid metabolic process GO:0043436 103 0.025
multi multicellular organism process GO:0044706 123 0.025
synaptic transmission GO:0007268 288 0.024
phototaxis GO:0042331 21 0.024
organic substance catabolic process GO:1901575 308 0.024
organic acid metabolic process GO:0006082 103 0.024
positive regulation of cellular component organization GO:0051130 156 0.024
regulation of cell cycle GO:0051726 291 0.024
maintenance of location GO:0051235 73 0.024
organonitrogen compound catabolic process GO:1901565 128 0.023
peripheral nervous system development GO:0007422 52 0.023
cellular response to heat GO:0034605 24 0.023
regulation of nervous system development GO:0051960 248 0.023
embryonic development via the syncytial blastoderm GO:0001700 148 0.023
regulation of response to stress GO:0080134 200 0.023
protein modification process GO:0036211 438 0.023
regulation of phosphorus metabolic process GO:0051174 210 0.023
positive regulation of signal transduction GO:0009967 223 0.023
actin cytoskeleton organization GO:0030036 206 0.022
cellular response to external stimulus GO:0071496 66 0.022
regulation of cell differentiation GO:0045595 302 0.022
cellular ketone metabolic process GO:0042180 24 0.022
immune response GO:0006955 246 0.022
blastoderm segmentation GO:0007350 159 0.022
toxin catabolic process GO:0009407 1 0.022
regulation of cellular amine metabolic process GO:0033238 3 0.022
positive regulation of biosynthetic process GO:0009891 316 0.022
epidermal cell differentiation GO:0009913 51 0.022
ras protein signal transduction GO:0007265 88 0.022
regulation of cellular ketone metabolic process GO:0010565 3 0.021
immune system process GO:0002376 347 0.021
septate junction assembly GO:0019991 26 0.021
stem cell proliferation GO:0072089 88 0.021
intracellular signal transduction GO:0035556 300 0.021
apical junction assembly GO:0043297 32 0.021
regulation of apoptotic process GO:0042981 130 0.021
eye development GO:0001654 323 0.021
male courtship behavior veined wing generated song production GO:0045433 20 0.021
actin filament based process GO:0030029 220 0.021
regulation of cellular amino acid metabolic process GO:0006521 0 0.021
organelle assembly GO:0070925 198 0.021
phosphorylation GO:0016310 294 0.021
cell junction assembly GO:0034329 42 0.021
macromolecular complex assembly GO:0065003 256 0.021
cellular hormone metabolic process GO:0034754 23 0.021
secretion by cell GO:0032940 101 0.021
negative regulation of nucleic acid templated transcription GO:1903507 240 0.021
response to copper ion GO:0046688 4 0.020
cell cell junction organization GO:0045216 55 0.020
signal release GO:0023061 49 0.020
lipid homeostasis GO:0055088 33 0.020
dendrite development GO:0016358 204 0.020
negative regulation of signal transduction GO:0009968 206 0.020
negative regulation of macromolecule biosynthetic process GO:0010558 270 0.020
enzyme linked receptor protein signaling pathway GO:0007167 179 0.020
cellular catabolic process GO:0044248 372 0.020
regulation of anatomical structure morphogenesis GO:0022603 242 0.020
exocrine system development GO:0035272 162 0.020
cellular protein modification process GO:0006464 438 0.020
hair cell differentiation GO:0035315 47 0.020
chaeta development GO:0022416 97 0.019
anion homeostasis GO:0055081 3 0.019
regulation of behavior GO:0050795 75 0.019
regulation of tube size GO:0035150 46 0.019
rho protein signal transduction GO:0007266 14 0.019
sensory perception of smell GO:0007608 80 0.019
response to nutrient levels GO:0031667 114 0.019
cell maturation GO:0048469 144 0.019
response to organic cyclic compound GO:0014070 89 0.019
actin filament organization GO:0007015 126 0.019
response to paraquat GO:1901562 4 0.019
cellular response to dna damage stimulus GO:0006974 223 0.019
negative regulation of nitrogen compound metabolic process GO:0051172 265 0.019
cell junction organization GO:0034330 57 0.019
response to toxic substance GO:0009636 22 0.019
regulation of cell death GO:0010941 173 0.019
locomotory behavior GO:0007626 176 0.018
chromosome segregation GO:0007059 157 0.018
carbohydrate derivative metabolic process GO:1901135 217 0.018
cell division GO:0051301 248 0.018
medium chain fatty acid metabolic process GO:0051791 1 0.018
negative regulation of cellular metabolic process GO:0031324 382 0.018
positive regulation of cellular biosynthetic process GO:0031328 316 0.018
regulation of cell morphogenesis GO:0022604 163 0.018
cell adhesion involved in heart morphogenesis GO:0061343 12 0.018
response to wounding GO:0009611 94 0.018
spindle organization GO:0007051 253 0.018
positive regulation of rna biosynthetic process GO:1902680 266 0.018
salivary gland development GO:0007431 162 0.018
regulation of cell projection organization GO:0031344 92 0.018
catabolic process GO:0009056 409 0.018
tergite morphogenesis GO:0007490 1 0.017
negative regulation of cellular biosynthetic process GO:0031327 277 0.017
positive regulation of gene expression GO:0010628 290 0.017
regulation of neurotransmitter levels GO:0001505 38 0.017
regulation of cell proliferation GO:0042127 163 0.017
segmentation GO:0035282 207 0.017
negative regulation of biosynthetic process GO:0009890 277 0.017
negative regulation of programmed cell death GO:0043069 72 0.017
protein complex biogenesis GO:0070271 201 0.017
digestive tract development GO:0048565 149 0.017
negative regulation of transcription dna templated GO:0045892 237 0.017
fat soluble vitamin biosynthetic process GO:0042362 1 0.017
nucleoside phosphate metabolic process GO:0006753 162 0.016
regulation of catalytic activity GO:0050790 185 0.016
regulation of neuron projection development GO:0010975 69 0.016
gland morphogenesis GO:0022612 145 0.016
salivary gland morphogenesis GO:0007435 145 0.016
camera type eye development GO:0043010 4 0.016
regulation of ras protein signal transduction GO:0046578 93 0.016
developmental growth GO:0048589 280 0.016
vitamin metabolic process GO:0006766 2 0.016
positive regulation of nervous system development GO:0051962 69 0.016
cellular macromolecule localization GO:0070727 220 0.016
regulation of localization GO:0032879 275 0.016
cellular response to organic substance GO:0071310 132 0.016
negative regulation of signaling GO:0023057 219 0.016
regulation of growth GO:0040008 233 0.016
positive regulation of rna metabolic process GO:0051254 271 0.016
organic substance transport GO:0071702 257 0.016
embryo development ending in birth or egg hatching GO:0009792 152 0.016
small gtpase mediated signal transduction GO:0007264 88 0.016
positive regulation of nucleic acid templated transcription GO:1903508 266 0.016
cuticle development GO:0042335 86 0.016
spermatogenesis GO:0007283 200 0.015
positive regulation of transcription from rna polymerase ii promoter GO:0045944 204 0.015
alcohol metabolic process GO:0006066 25 0.015
organic cyclic compound catabolic process GO:1901361 168 0.015
positive regulation of intracellular signal transduction GO:1902533 116 0.015
negative regulation of rna biosynthetic process GO:1902679 240 0.015
positive regulation of phosphorus metabolic process GO:0010562 139 0.015
toxin metabolic process GO:0009404 2 0.015
negative regulation of organelle organization GO:0010639 56 0.015
maintenance of imaginal disc derived wing hair orientation GO:0035321 3 0.015
anterior posterior pattern specification GO:0009952 136 0.015
protein complex assembly GO:0006461 200 0.015
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 116 0.015
regulation of phosphate metabolic process GO:0019220 210 0.015
compound eye morphogenesis GO:0001745 249 0.015
fat soluble vitamin metabolic process GO:0006775 1 0.014
male courtship behavior veined wing vibration GO:0016545 21 0.014
regulation of molecular function GO:0065009 217 0.014
developmental programmed cell death GO:0010623 138 0.014
negative regulation of developmental process GO:0051093 201 0.014
dorsal ventral axis specification GO:0009950 66 0.014
response to extracellular stimulus GO:0009991 116 0.014
lipid biosynthetic process GO:0008610 46 0.014
digestive tract morphogenesis GO:0048546 127 0.014
response to lipopolysaccharide GO:0032496 4 0.014
muscle structure development GO:0061061 224 0.014
female meiosis chromosome segregation GO:0016321 33 0.014
synaptic target recognition GO:0008039 45 0.014
energy taxis GO:0009453 21 0.014
cellular response to ethanol GO:0071361 4 0.014
compound eye development GO:0048749 307 0.014
head development GO:0060322 135 0.014
cell adhesion GO:0007155 136 0.014
regulation of protein metabolic process GO:0051246 256 0.014
estrogen metabolic process GO:0008210 1 0.014
organic hydroxy compound catabolic process GO:1901616 4 0.014
regulation of developmental growth GO:0048638 174 0.014
positive regulation of cell migration GO:0030335 2 0.014
tube development GO:0035295 244 0.014
mapk cascade GO:0000165 107 0.013
ecdysteroid metabolic process GO:0045455 19 0.013
developmental maturation GO:0021700 172 0.013
body morphogenesis GO:0010171 2 0.013
innate immune response GO:0045087 144 0.013
digestive system development GO:0055123 149 0.013
tripartite regional subdivision GO:0007351 103 0.013
regulation of lipid transport GO:0032368 3 0.013
regulation of phosphorylation GO:0042325 147 0.013
locomotor rhythm GO:0045475 56 0.013
response to lipid GO:0033993 38 0.013
positive regulation of transcription dna templated GO:0045893 266 0.013
regulation of epithelial cell proliferation GO:0050678 4 0.013
sensory perception of chemical stimulus GO:0007606 116 0.013
sterol homeostasis GO:0055092 4 0.013
aromatic compound catabolic process GO:0019439 166 0.013
response to endogenous stimulus GO:0009719 119 0.013
sensory organ morphogenesis GO:0090596 260 0.013
ecdysteroid biosynthetic process GO:0045456 15 0.013
nucleotide metabolic process GO:0009117 161 0.013
negative regulation of apoptotic process GO:0043066 63 0.013
courtship behavior GO:0007619 68 0.013
Fly
determination of adult lifespan GO:0008340 137 0.013
eye morphogenesis GO:0048592 260 0.013
mitochondrion organization GO:0007005 65 0.013
cellular response to mechanical stimulus GO:0071260 2 0.013
sensory perception GO:0007600 196 0.013
anterior posterior axis specification embryo GO:0008595 103 0.013
secretion GO:0046903 109 0.012
regulation of mapk cascade GO:0043408 92 0.012
endomembrane system organization GO:0010256 119 0.012
cellular protein localization GO:0034613 160 0.012
histolysis GO:0007559 102 0.012
positive regulation of phosphate metabolic process GO:0045937 139 0.012
tissue death GO:0016271 102 0.012
nucleobase containing small molecule metabolic process GO:0055086 174 0.012
positive regulation of defense response GO:0031349 59 0.012
response to heat GO:0009408 63 0.012
peptidyl amino acid modification GO:0018193 105 0.012
response to monosaccharide GO:0034284 4 0.012
connective tissue development GO:0061448 3 0.012
embryonic axis specification GO:0000578 107 0.012
cellular macromolecule catabolic process GO:0044265 136 0.012
regulation of cellular component size GO:0032535 98 0.012
intracellular transport GO:0046907 228 0.012
cellular nitrogen compound catabolic process GO:0044270 165 0.012
positive regulation of cell motility GO:2000147 3 0.012
cellular lipid metabolic process GO:0044255 83 0.012
lipid catabolic process GO:0016042 21 0.012
negative regulation of cellular protein metabolic process GO:0032269 85 0.012
positive regulation of phosphorylation GO:0042327 87 0.012
regulation of axonogenesis GO:0050770 32 0.012
macromolecule catabolic process GO:0009057 161 0.012
cellular response to oxidative stress GO:0034599 28 0.012
regulation of cell size GO:0008361 63 0.011
imaginal disc pattern formation GO:0007447 91 0.011
response to inorganic substance GO:0010035 44 0.011
dorsal ventral pattern formation GO:0009953 133 0.011
cellular response to oxygen containing compound GO:1901701 79 0.011
response to oxygen levels GO:0070482 59 0.011
positive regulation of molecular function GO:0044093 136 0.011
cell growth GO:0016049 108 0.011
cellular response to biotic stimulus GO:0071216 4 0.011
salivary gland cell autophagic cell death GO:0035071 83 0.011
regulation of cellular protein metabolic process GO:0032268 243 0.011
defense response to gram negative bacterium GO:0050829 94 0.011
negative regulation of nucleobase containing compound metabolic process GO:0045934 261 0.011
negative regulation of rna metabolic process GO:0051253 251 0.011
protein phosphorylation GO:0006468 169 0.011
proximal distal pattern formation GO:0009954 15 0.011
neuromuscular junction development GO:0007528 149 0.011
regulation of cellular localization GO:0060341 136 0.011
transition metal ion transport GO:0000041 16 0.011
positive regulation of catalytic activity GO:0043085 118 0.011
hormone metabolic process GO:0042445 33 0.011
positive regulation of cell development GO:0010720 61 0.011
response to nitrogen compound GO:1901698 90 0.011
heterocycle catabolic process GO:0046700 166 0.011
negative chemotaxis GO:0050919 15 0.011
male courtship behavior GO:0008049 63 0.011
circadian behavior GO:0048512 76 0.011
positive regulation of neurogenesis GO:0050769 41 0.011
chromosome organization GO:0051276 360 0.011
cellular component assembly involved in morphogenesis GO:0010927 151 0.011
response to glucose GO:0009749 2 0.011
regulation of neuron differentiation GO:0045664 103 0.011
positive regulation of cell differentiation GO:0045597 64 0.011
nucleobase containing compound catabolic process GO:0034655 165 0.011
limb development GO:0060173 1 0.011
organonitrogen compound biosynthetic process GO:1901566 117 0.011
regulation of small gtpase mediated signal transduction GO:0051056 93 0.011
dorsal closure GO:0007391 79 0.011
cellular response to nutrient levels GO:0031669 62 0.011
purine containing compound metabolic process GO:0072521 155 0.011
cellular response to endogenous stimulus GO:0071495 80 0.010
male courtship behavior veined wing extension GO:0048065 22 0.010
establishment of protein localization GO:0045184 163 0.010
chitin based cuticle development GO:0040003 49 0.010
cation transmembrane transport GO:0098655 88 0.010
regulation of defense response GO:0031347 102 0.010
retina development in camera type eye GO:0060041 4 0.010
glycerolipid metabolic process GO:0046486 34 0.010
purine ribonucleoside metabolic process GO:0046128 127 0.010
signal transduction by phosphorylation GO:0023014 107 0.010
muscle organ development GO:0007517 127 0.010
monocarboxylic acid transport GO:0015718 3 0.010
wing disc pattern formation GO:0035222 66 0.010
antimicrobial humoral response GO:0019730 99 0.010

Jhe disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.032
hypertension DOID:10763 0 0.027
artery disease DOID:0050828 0 0.027
vascular disease DOID:178 0 0.027
cardiovascular system disease DOID:1287 0 0.027
essential hypertension DOID:10825 0 0.022
disease of metabolism DOID:0014667 0 0.019
carbohydrate metabolism disease DOID:0050013 0 0.017
glucose metabolism disease DOID:4194 0 0.017
acquired metabolic disease DOID:0060158 0 0.017
nervous system disease DOID:863 0 0.013
inherited metabolic disorder DOID:655 0 0.012