Drosophila melanogaster

4 known processes

CG8420 (Dmel_CG8420)

CG8420 gene product from transcript CG8420-RA

(Aliases: anon-WO0140519.182,Dmel\CG8420)

CG8420 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
defense response GO:0006952 300 0.072
neurological system process GO:0050877 358 0.070
proteolysis GO:0006508 192 0.057
epithelial cell differentiation GO:0030855 322 0.052
response to other organism GO:0051707 293 0.049
single organism behavior GO:0044708 391 0.042
negative regulation of gene expression GO:0010629 387 0.041
imaginal disc derived wing morphogenesis GO:0007476 337 0.038
response to external biotic stimulus GO:0043207 293 0.038
imaginal disc derived appendage morphogenesis GO:0035114 395 0.037
sensory perception GO:0007600 196 0.036
appendage development GO:0048736 401 0.036
epithelial cell development GO:0002064 274 0.033
catabolic process GO:0009056 409 0.033
vesicle mediated transport GO:0016192 381 0.032
cellular catabolic process GO:0044248 372 0.032
organic acid metabolic process GO:0006082 103 0.030
cellular macromolecule localization GO:0070727 220 0.030
post embryonic appendage morphogenesis GO:0035120 385 0.030
negative regulation of biosynthetic process GO:0009890 277 0.030
positive regulation of rna metabolic process GO:0051254 271 0.030
response to organic substance GO:0010033 284 0.030
response to lipopolysaccharide GO:0032496 4 0.029
regulation of transcription from rna polymerase ii promoter GO:0006357 378 0.029
appendage morphogenesis GO:0035107 397 0.029
regionalization GO:0003002 416 0.029
imaginal disc derived appendage development GO:0048737 399 0.029
protein modification process GO:0036211 438 0.029
positive regulation of transcription dna templated GO:0045893 266 0.028
organonitrogen compound metabolic process GO:1901564 318 0.028
small molecule metabolic process GO:0044281 305 0.028
carboxylic acid metabolic process GO:0019752 92 0.028
wing disc morphogenesis GO:0007472 344 0.027
transcription from rna polymerase ii promoter GO:0006366 368 0.027
response to oxygen containing compound GO:1901700 200 0.027
positive regulation of nucleic acid templated transcription GO:1903508 266 0.027
negative regulation of cellular metabolic process GO:0031324 382 0.026
positive regulation of macromolecule metabolic process GO:0010604 405 0.025
immune response GO:0006955 246 0.025
segmentation GO:0035282 207 0.025
positive regulation of cell communication GO:0010647 250 0.025
organic substance catabolic process GO:1901575 308 0.025
organic substance transport GO:0071702 257 0.025
phagocytosis GO:0006909 215 0.025
cellular protein modification process GO:0006464 438 0.025
positive regulation of rna biosynthetic process GO:1902680 266 0.025
adult behavior GO:0030534 137 0.024
positive regulation of nucleobase containing compound metabolic process GO:0045935 332 0.024
positive regulation of macromolecule biosynthetic process GO:0010557 283 0.024
estrogen metabolic process GO:0008210 1 0.024
endocytosis GO:0006897 310 0.024
positive regulation of cellular biosynthetic process GO:0031328 316 0.024
response to abiotic stimulus GO:0009628 341 0.024
positive regulation of biosynthetic process GO:0009891 316 0.024
embryonic pattern specification GO:0009880 174 0.024
response to biotic stimulus GO:0009607 294 0.024
aggressive behavior GO:0002118 63 0.024
cell death GO:0008219 279 0.023
establishment of localization in cell GO:0051649 402 0.023
nuclear division GO:0000280 332 0.023
locomotory behavior GO:0007626 176 0.023
blastoderm segmentation GO:0007350 159 0.023
cellular response to chemical stimulus GO:0070887 199 0.023
positive regulation of nitrogen compound metabolic process GO:0051173 354 0.022
proteolysis involved in cellular protein catabolic process GO:0051603 83 0.022
defense response to other organism GO:0098542 225 0.022
kidney development GO:0001822 3 0.022
body morphogenesis GO:0010171 2 0.022
negative regulation of macromolecule biosynthetic process GO:0010558 270 0.022
organelle fission GO:0048285 340 0.022
actin filament organization GO:0007015 126 0.022
regulation of multicellular organismal development GO:2000026 414 0.022
steroid catabolic process GO:0006706 1 0.021
positive regulation of gene expression GO:0010628 290 0.021
axis specification GO:0009798 167 0.021
carbohydrate derivative metabolic process GO:1901135 217 0.021
compound eye development GO:0048749 307 0.021
protein localization GO:0008104 284 0.021
actin filament based process GO:0030029 220 0.021
spindle organization GO:0007051 253 0.020
negative regulation of cellular macromolecule biosynthetic process GO:2000113 267 0.020
anterior posterior pattern specification GO:0009952 136 0.020
regulation of protein metabolic process GO:0051246 256 0.020
positive regulation of response to stimulus GO:0048584 323 0.020
regulation of localization GO:0032879 275 0.020
negative regulation of nitrogen compound metabolic process GO:0051172 265 0.020
negative regulation of rna metabolic process GO:0051253 251 0.020
humoral immune response GO:0006959 117 0.020
cellular amino acid metabolic process GO:0006520 61 0.019
positive regulation of signaling GO:0023056 243 0.019
chemotaxis GO:0006935 249 0.019
tube morphogenesis GO:0035239 191 0.019
cellular macromolecule catabolic process GO:0044265 136 0.019
regulation of cell cycle GO:0051726 291 0.019
death GO:0016265 284 0.019
xenobiotic catabolic process GO:0042178 1 0.019
immune system process GO:0002376 347 0.019
axon development GO:0061564 297 0.019
hormone catabolic process GO:0042447 3 0.019
regulation of anatomical structure morphogenesis GO:0022603 242 0.019
multi organism behavior GO:0051705 175 0.019
sensory organ morphogenesis GO:0090596 260 0.019
salivary gland development GO:0007431 162 0.019
actin cytoskeleton organization GO:0030036 206 0.018
mitotic spindle organization GO:0007052 220 0.018
cellular component assembly involved in morphogenesis GO:0010927 151 0.018
macromolecular complex assembly GO:0065003 256 0.018
growth GO:0040007 359 0.018
eye morphogenesis GO:0048592 260 0.018
protein modification by small protein conjugation or removal GO:0070647 106 0.018
respiratory system development GO:0060541 213 0.018
dendrite morphogenesis GO:0048813 199 0.018
ethanolamine containing compound metabolic process GO:0042439 4 0.018
regulation of transport GO:0051049 181 0.018
columnar cuboidal epithelial cell differentiation GO:0002065 256 0.018
negative regulation of nucleic acid templated transcription GO:1903507 240 0.018
oxoacid metabolic process GO:0043436 103 0.018
regulation of cellular component biogenesis GO:0044087 201 0.017
developmental programmed cell death GO:0010623 138 0.017
forebrain development GO:0030900 2 0.017
open tracheal system development GO:0007424 204 0.017
developmental maturation GO:0021700 172 0.017
benzene containing compound metabolic process GO:0042537 3 0.017
negative regulation of signal transduction GO:0009968 206 0.017
response to bacterium GO:0009617 198 0.017
embryo development ending in birth or egg hatching GO:0009792 152 0.017
regulation of multi organism process GO:0043900 131 0.017
exocrine system development GO:0035272 162 0.017
negative regulation of cellular biosynthetic process GO:0031327 277 0.017
single organism biosynthetic process GO:0044711 206 0.017
gland development GO:0048732 191 0.016
regulation of proteolysis GO:0030162 87 0.016
organelle assembly GO:0070925 198 0.016
anterior posterior axis specification GO:0009948 109 0.016
cellular response to organic substance GO:0071310 132 0.016
rna processing GO:0006396 147 0.016
response to starvation GO:0042594 97 0.016
regulation of molecular function GO:0065009 217 0.016
axon guidance GO:0007411 233 0.016
embryonic axis specification GO:0000578 107 0.016
adult locomotory behavior GO:0008344 76 0.016
eye development GO:0001654 323 0.016
phosphorylation GO:0016310 294 0.016
regulation of cellular protein metabolic process GO:0032268 243 0.016
dendrite development GO:0016358 204 0.016
lipid metabolic process GO:0006629 121 0.016
cellular protein catabolic process GO:0044257 83 0.016
single organism cellular localization GO:1902580 180 0.016
cellular amine metabolic process GO:0044106 12 0.016
regulation of notch signaling pathway GO:0008593 100 0.015
aromatic compound catabolic process GO:0019439 166 0.015
regulation of cellular catabolic process GO:0031329 157 0.015
regulation of epithelial cell differentiation GO:0030856 4 0.015
negative regulation of rna biosynthetic process GO:1902679 240 0.015
amine metabolic process GO:0009308 12 0.015
ras protein signal transduction GO:0007265 88 0.015
positive regulation of signal transduction GO:0009967 223 0.015
mitotic cell cycle phase transition GO:0044772 138 0.015
homeostatic process GO:0042592 199 0.015
notch signaling pathway GO:0007219 120 0.015
defense response to fungus GO:0050832 48 0.015
cell division GO:0051301 248 0.015
ion transport GO:0006811 145 0.015
protein complex assembly GO:0006461 200 0.015
sensory perception of mechanical stimulus GO:0050954 72 0.015
positive regulation of transcription from rna polymerase ii promoter GO:0045944 204 0.015
modification dependent macromolecule catabolic process GO:0043632 79 0.015
ovarian follicle cell development GO:0030707 248 0.015
organic hydroxy compound metabolic process GO:1901615 83 0.015
detection of stimulus involved in sensory perception GO:0050906 92 0.015
taxis GO:0042330 304 0.015
defense response to bacterium GO:0042742 178 0.014
negative regulation of signaling GO:0023057 219 0.014
chromosome organization GO:0051276 360 0.014
negative regulation of cell communication GO:0010648 223 0.014
camera type eye development GO:0043010 4 0.014
spermatogenesis GO:0007283 200 0.014
programmed cell death GO:0012501 257 0.014
intracellular signal transduction GO:0035556 300 0.014
oocyte construction GO:0007308 112 0.014
regulation of cellular ketone metabolic process GO:0010565 3 0.014
cellularization GO:0007349 90 0.014
macromolecule catabolic process GO:0009057 161 0.014
protein maturation GO:0051604 71 0.014
regulation of gene expression epigenetic GO:0040029 128 0.014
protein processing GO:0016485 68 0.014
modification dependent protein catabolic process GO:0019941 78 0.014
mating GO:0007618 120 0.014
cellular amide metabolic process GO:0043603 80 0.014
regulation of phosphorus metabolic process GO:0051174 210 0.014
organic cyclic compound catabolic process GO:1901361 168 0.014
regulation of catabolic process GO:0009894 170 0.014
chromosome segregation GO:0007059 157 0.014
tripartite regional subdivision GO:0007351 103 0.014
regulation of cellular localization GO:0060341 136 0.014
digestive tract development GO:0048565 149 0.014
compound eye morphogenesis GO:0001745 249 0.014
eggshell formation GO:0030703 105 0.014
regulation of immune system process GO:0002682 176 0.014
negative regulation of nucleobase containing compound metabolic process GO:0045934 261 0.014
response to fungus GO:0009620 50 0.014
cellular response to dna damage stimulus GO:0006974 223 0.014
anterior posterior axis specification embryo GO:0008595 103 0.014
cell maturation GO:0048469 144 0.014
phosphatidylethanolamine metabolic process GO:0046337 1 0.014
mushroom body development GO:0016319 70 0.014
regulation of cell development GO:0060284 215 0.014
chemosensory behavior GO:0007635 106 0.014
response to radiation GO:0009314 155 0.014
ubiquitin dependent protein catabolic process GO:0006511 78 0.014
regulation of embryonic development GO:0045995 68 0.014
gene silencing GO:0016458 138 0.014
regulation of mitotic cell cycle phase transition GO:1901990 130 0.014
telencephalon development GO:0021537 2 0.013
androgen metabolic process GO:0008209 1 0.013
negative regulation of transcription dna templated GO:0045892 237 0.013
morphogenesis of an epithelium GO:0002009 276 0.013
regulation of mitotic cell cycle GO:0007346 190 0.013
single organism catabolic process GO:0044712 228 0.013
regulation of cellular amino acid metabolic process GO:0006521 0 0.013
small gtpase mediated signal transduction GO:0007264 88 0.013
multicellular organismal aging GO:0010259 140 0.013
cellular ketone metabolic process GO:0042180 24 0.013
posttranscriptional regulation of gene expression GO:0010608 145 0.013
positive regulation of cell motility GO:2000147 3 0.013
gland morphogenesis GO:0022612 145 0.013
response to glucose GO:0009749 2 0.013
sensory perception of chemical stimulus GO:0007606 116 0.013
protein catabolic process GO:0030163 101 0.013
regulation of cell morphogenesis GO:0022604 163 0.013
regulation of cellular amine metabolic process GO:0033238 3 0.013
embryonic morphogenesis GO:0048598 206 0.013
photoreceptor cell differentiation GO:0046530 170 0.013
cell cycle phase transition GO:0044770 140 0.013
cell motility GO:0048870 251 0.013
pigment metabolic process GO:0042440 84 0.013
regulation of cell cycle process GO:0010564 181 0.013
negative regulation of response to stimulus GO:0048585 258 0.013
regulation of cell differentiation GO:0045595 302 0.013
biological adhesion GO:0022610 138 0.013
response to endogenous stimulus GO:0009719 119 0.013
eye photoreceptor cell differentiation GO:0001754 145 0.013
regulation of cell death GO:0010941 173 0.013
carbohydrate derivative biosynthetic process GO:1901137 85 0.013
carbohydrate metabolic process GO:0005975 82 0.013
cellular response to ethanol GO:0071361 4 0.013
intracellular transport GO:0046907 228 0.013
mesoderm development GO:0007498 78 0.012
regulation of cell shape GO:0008360 113 0.012
endomembrane system organization GO:0010256 119 0.012
columnar cuboidal epithelial cell development GO:0002066 249 0.012
male gamete generation GO:0048232 201 0.012
response to extracellular stimulus GO:0009991 116 0.012
developmental growth GO:0048589 280 0.012
protein transport GO:0015031 155 0.012
tissue morphogenesis GO:0048729 297 0.012
cholesterol homeostasis GO:0042632 3 0.012
cell migration GO:0016477 238 0.012
ribonucleotide metabolic process GO:0009259 145 0.012
protein complex biogenesis GO:0070271 201 0.012
negative regulation of cellular protein metabolic process GO:0032269 85 0.012
tube development GO:0035295 244 0.012
oocyte axis specification GO:0007309 108 0.012
apoptotic process GO:0006915 159 0.012
tissue death GO:0016271 102 0.012
neuron projection guidance GO:0097485 241 0.012
negative regulation of developmental process GO:0051093 201 0.012
response to monosaccharide GO:0034284 4 0.012
single organism intracellular transport GO:1902582 207 0.012
inter male aggressive behavior GO:0002121 60 0.012
establishment of protein localization GO:0045184 163 0.012
negative regulation of mitotic cell cycle phase transition GO:1901991 103 0.012
localization of cell GO:0051674 257 0.012
regulation of phosphate metabolic process GO:0019220 210 0.012
cell adhesion GO:0007155 136 0.012
limb development GO:0060173 1 0.012
rna localization GO:0006403 115 0.012
positive regulation of cellular amine metabolic process GO:0033240 0 0.012
negative regulation of protein metabolic process GO:0051248 85 0.012
digestive system development GO:0055123 149 0.012
secretion GO:0046903 109 0.012
mitotic nuclear division GO:0007067 213 0.012
anion homeostasis GO:0055081 3 0.012
regulation of hormone levels GO:0010817 40 0.011
salivary gland histolysis GO:0035070 88 0.011
cellular protein localization GO:0034613 160 0.011
salivary gland morphogenesis GO:0007435 145 0.011
epidermis development GO:0008544 65 0.011
aging GO:0007568 143 0.011
antimicrobial humoral response GO:0019730 99 0.011
cell projection assembly GO:0030031 94 0.011
cellular nitrogen compound catabolic process GO:0044270 165 0.011
regulation of response to stress GO:0080134 200 0.011
proteasomal protein catabolic process GO:0010498 59 0.011
regulation of intracellular signal transduction GO:1902531 236 0.011
vesicle organization GO:0016050 44 0.011
axonogenesis GO:0007409 290 0.011
response to organophosphorus GO:0046683 2 0.011
establishment or maintenance of cell polarity GO:0007163 167 0.011
regulation of programmed cell death GO:0043067 152 0.011
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 54 0.011
mesenchymal cell differentiation GO:0048762 1 0.011
alditol phosphate metabolic process GO:0052646 2 0.011
cellular response to oxygen containing compound GO:1901701 79 0.011
renal system development GO:0072001 72 0.011
multi multicellular organism process GO:0044706 123 0.011
mesenchymal cell development GO:0014031 1 0.011
head involution GO:0008258 35 0.011
chaeta development GO:0022416 97 0.011
innate immune response GO:0045087 144 0.011
rna splicing GO:0008380 83 0.011
skin development GO:0043588 65 0.011
kidney epithelium development GO:0072073 3 0.011
cellular homeostasis GO:0019725 80 0.011
hair cell differentiation GO:0035315 47 0.011
regulation of gene silencing GO:0060968 63 0.011
cytoskeleton dependent cytokinesis GO:0061640 81 0.011
regulation of response to biotic stimulus GO:0002831 63 0.011
sterol homeostasis GO:0055092 4 0.011
sister chromatid segregation GO:0000819 92 0.011
regulation of epithelial cell proliferation GO:0050678 4 0.011
wound healing GO:0042060 75 0.011
positive regulation of apoptotic signaling pathway GO:2001235 4 0.010
dorsal ventral pattern formation GO:0009953 133 0.010
reproductive behavior GO:0019098 122 0.010
response to nutrient levels GO:0031667 114 0.010
chemical homeostasis GO:0048878 92 0.010
mrna metabolic process GO:0016071 124 0.010
microtubule organizing center organization GO:0031023 168 0.010
epidermal cell differentiation GO:0009913 51 0.010
synaptic transmission GO:0007268 288 0.010
inorganic ion transmembrane transport GO:0098660 73 0.010
negative regulation of multicellular organismal process GO:0051241 142 0.010
intracellular mrna localization GO:0008298 66 0.010
regulation of i kappab kinase nf kappab signaling GO:0043122 2 0.010
regulation of nervous system development GO:0051960 248 0.010
transmembrane transport GO:0055085 139 0.010
chorion containing eggshell formation GO:0007304 105 0.010
nephron development GO:0072006 3 0.010
lateral inhibition GO:0046331 206 0.010
spermatid differentiation GO:0048515 114 0.010
ion transmembrane transport GO:0034220 122 0.010
positive regulation of cellular amino acid metabolic process GO:0045764 0 0.010
mitotic sister chromatid segregation GO:0000070 87 0.010
cell cell signaling involved in cell fate commitment GO:0045168 210 0.010
regulation of cell cycle phase transition GO:1901987 130 0.010
secondary metabolic process GO:0019748 75 0.010
positive regulation of lipid storage GO:0010884 4 0.010
heterocycle catabolic process GO:0046700 166 0.010
peptide metabolic process GO:0006518 80 0.010
response to wounding GO:0009611 94 0.010

CG8420 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.038
disease of metabolism DOID:0014667 0 0.024
diabetes mellitus DOID:9351 0 0.016
type 2 diabetes mellitus DOID:9352 0 0.016
carbohydrate metabolism disease DOID:0050013 0 0.016
glucose metabolism disease DOID:4194 0 0.016
acquired metabolic disease DOID:0060158 0 0.016
nervous system disease DOID:863 0 0.014
inherited metabolic disorder DOID:655 0 0.013
cancer DOID:162 0 0.010
disease of cellular proliferation DOID:14566 0 0.010