Drosophila melanogaster

160 known processes

MED24 (Dmel_CG7999)

Mediator complex subunit 24

(Aliases: Dmel\CG7999,dTRAP100,Med24,CG7999,Trap100)

MED24 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
regulation of cell differentiation GO:0045595 302 0.636
Mouse
regulation of cellular component biogenesis GO:0044087 201 0.567
positive regulation of cellular biosynthetic process GO:0031328 316 0.429
gland development GO:0048732 191 0.407
regulation of transcription from rna polymerase ii promoter GO:0006357 378 0.405
positive regulation of transcription from rna polymerase ii promoter GO:0045944 204 0.384
salivary gland development GO:0007431 162 0.355
positive regulation of nucleobase containing compound metabolic process GO:0045935 332 0.331
induction of programmed cell death by hormones GO:0035081 12 0.315
larval midgut cell programmed cell death GO:0035096 19 0.286
positive regulation of nitrogen compound metabolic process GO:0051173 354 0.266
larval midgut histolysis GO:0035069 22 0.248
induction of programmed cell death by ecdysone GO:0035078 12 0.246
death GO:0016265 284 0.245
negative regulation of cellular metabolic process GO:0031324 382 0.238
intracellular transport GO:0046907 228 0.216
negative regulation of gene expression GO:0010629 387 0.213
negative regulation of nucleobase containing compound metabolic process GO:0045934 261 0.203
cell death GO:0008219 279 0.198
cell motility GO:0048870 251 0.192
negative regulation of rna biosynthetic process GO:1902679 240 0.191
response to mechanical stimulus GO:0009612 28 0.191
morphogenesis of an epithelium GO:0002009 276 0.185
regulation of cell development GO:0060284 215 0.182
cell proliferation GO:0008283 299 0.175
gland morphogenesis GO:0022612 145 0.173
positive regulation of transcription dna templated GO:0045893 266 0.172
regulation of anatomical structure morphogenesis GO:0022603 242 0.171
regulation of programmed cell death GO:0043067 152 0.158
cellular response to chemical stimulus GO:0070887 199 0.157
exocrine system development GO:0035272 162 0.153
transcription from rna polymerase ii promoter GO:0006366 368 0.152
tissue morphogenesis GO:0048729 297 0.151
Zebrafish
positive regulation of cellular component organization GO:0051130 156 0.148
positive regulation of biosynthetic process GO:0009891 316 0.147
purine ribonucleoside catabolic process GO:0046130 112 0.147
regulation of neurogenesis GO:0050767 158 0.147
positive regulation of macromolecule biosynthetic process GO:0010557 283 0.142
salivary gland morphogenesis GO:0007435 145 0.138
positive regulation of nucleic acid templated transcription GO:1903508 266 0.135
positive regulation of rna metabolic process GO:0051254 271 0.135
negative regulation of nitrogen compound metabolic process GO:0051172 265 0.133
tube morphogenesis GO:0035239 191 0.133
positive regulation of macromolecule metabolic process GO:0010604 405 0.126
regulation of cell death GO:0010941 173 0.123
salivary gland histolysis GO:0035070 88 0.123
ecdysone mediated induction of salivary gland cell autophagic cell death GO:0035072 12 0.120
positive regulation of rna biosynthetic process GO:1902680 266 0.119
regulation of multicellular organismal development GO:2000026 414 0.115
camera type eye development GO:0043010 4 0.113
Zebrafish
positive regulation of response to stimulus GO:0048584 323 0.112
induction of programmed cell death GO:0012502 12 0.111
negative regulation of developmental process GO:0051093 201 0.110
Mouse
negative regulation of rna metabolic process GO:0051253 251 0.108
cellular catabolic process GO:0044248 372 0.106
negative regulation of biosynthetic process GO:0009890 277 0.105
negative regulation of macromolecule biosynthetic process GO:0010558 270 0.104
eye development GO:0001654 323 0.104
Zebrafish
negative regulation of cellular biosynthetic process GO:0031327 277 0.101
vesicle mediated transport GO:0016192 381 0.097
tissue death GO:0016271 102 0.091
rna processing GO:0006396 147 0.088
negative regulation of transcription dna templated GO:0045892 237 0.085
regulation of dna metabolic process GO:0051052 34 0.084
developmental programmed cell death GO:0010623 138 0.083
localization of cell GO:0051674 257 0.083
imaginal disc derived appendage development GO:0048737 399 0.083
body morphogenesis GO:0010171 2 0.081
epithelial cell differentiation GO:0030855 322 0.080
negative regulation of nucleic acid templated transcription GO:1903507 240 0.078
negative regulation of cellular macromolecule biosynthetic process GO:2000113 267 0.076
lateral inhibition GO:0046331 206 0.076
negative regulation of cell differentiation GO:0045596 143 0.075
Mouse
response to oxygen containing compound GO:1901700 200 0.075
regulation of immune system process GO:0002682 176 0.074
dna methylation GO:0006306 4 0.074
organic substance transport GO:0071702 257 0.074
axon development GO:0061564 297 0.074
stem cell differentiation GO:0048863 117 0.073
Mouse
stem cell development GO:0048864 79 0.071
Mouse
programmed cell death GO:0012501 257 0.071
dendrite development GO:0016358 204 0.064
establishment of localization in cell GO:0051649 402 0.063
endocytosis GO:0006897 310 0.063
positive regulation of protein metabolic process GO:0051247 128 0.061
organophosphate catabolic process GO:0046434 112 0.061
organophosphate metabolic process GO:0019637 195 0.060
regulation of cell morphogenesis GO:0022604 163 0.059
salivary gland cell autophagic cell death GO:0035071 83 0.059
positive regulation of gene expression GO:0010628 290 0.058
macromolecular complex assembly GO:0065003 256 0.058
positive regulation of signaling GO:0023056 243 0.057
regulation of neuron projection development GO:0010975 69 0.056
histolysis GO:0007559 102 0.056
gene silencing GO:0016458 138 0.056
imaginal disc derived appendage morphogenesis GO:0035114 395 0.056
ribose phosphate metabolic process GO:0019693 145 0.056
retina morphogenesis in camera type eye GO:0060042 2 0.055
Zebrafish
positive regulation of signal transduction GO:0009967 223 0.055
immune system process GO:0002376 347 0.055
Zebrafish
internal protein amino acid acetylation GO:0006475 38 0.055
wnt signaling pathway GO:0016055 98 0.054
regulation of nervous system development GO:0051960 248 0.054
protein ubiquitination GO:0016567 70 0.054
retina development in camera type eye GO:0060041 4 0.053
Zebrafish
mitotic cell cycle phase transition GO:0044772 138 0.052
regulation of gene expression epigenetic GO:0040029 128 0.052
catabolic process GO:0009056 409 0.052
regulation of organelle organization GO:0033043 196 0.051
cell migration GO:0016477 238 0.051
response to organic cyclic compound GO:0014070 89 0.048
immune effector process GO:0002252 98 0.047
ribonucleoside metabolic process GO:0009119 127 0.047
tube development GO:0035295 244 0.047
organic substance catabolic process GO:1901575 308 0.046
nucleoside phosphate metabolic process GO:0006753 162 0.046
regulation of cellular ketone metabolic process GO:0010565 3 0.045
regulation of apoptotic signaling pathway GO:2001233 10 0.044
rna splicing via transesterification reactions with bulged adenosine as nucleophile GO:0000377 73 0.044
digestive tract morphogenesis GO:0048546 127 0.044
cellular response to insulin stimulus GO:0032869 28 0.043
oxoacid metabolic process GO:0043436 103 0.043
organonitrogen compound metabolic process GO:1901564 318 0.043
protein modification by small protein conjugation GO:0032446 79 0.042
morphogenesis of a branching epithelium GO:0061138 45 0.042
single organism biosynthetic process GO:0044711 206 0.042
purine ribonucleoside triphosphate metabolic process GO:0009205 119 0.041
regulation of cellular amine metabolic process GO:0033238 3 0.041
autophagy GO:0006914 108 0.041
small molecule metabolic process GO:0044281 305 0.041
purine nucleoside metabolic process GO:0042278 127 0.041
embryonic morphogenesis GO:0048598 206 0.041
positive regulation of developmental process GO:0051094 143 0.040
response to sterol GO:0036314 34 0.039
regulation of protein complex assembly GO:0043254 42 0.039
carboxylic acid metabolic process GO:0019752 92 0.038
protein localization GO:0008104 284 0.037
dna alkylation GO:0006305 4 0.037
negative regulation of multicellular organismal process GO:0051241 142 0.037
regulation of response to biotic stimulus GO:0002831 63 0.037
cell cell signaling involved in cell fate commitment GO:0045168 210 0.036
cellular amino acid metabolic process GO:0006520 61 0.036
autophagic cell death GO:0048102 83 0.036
regulation of cellular amino acid metabolic process GO:0006521 0 0.035
forebrain development GO:0030900 2 0.035
dna methylation or demethylation GO:0044728 4 0.034
response to organic substance GO:0010033 284 0.034
regulation of cell proliferation GO:0042127 163 0.034
regulation of cell cycle GO:0051726 291 0.033
protein acylation GO:0043543 42 0.033
homeostatic process GO:0042592 199 0.033
ribonucleoside triphosphate metabolic process GO:0009199 119 0.033
regulation of cell projection organization GO:0031344 92 0.033
regulation of proteolysis GO:0030162 87 0.032
neuron projection guidance GO:0097485 241 0.032
regulation of neuron differentiation GO:0045664 103 0.031
regulation of cell cycle process GO:0010564 181 0.031
defense response GO:0006952 300 0.030
posttranscriptional regulation of gene expression GO:0010608 145 0.030
heterochromatin organization GO:0070828 25 0.030
mesenchymal cell differentiation GO:0048762 1 0.030
protein acetylation GO:0006473 39 0.029
regulation of localization GO:0032879 275 0.029
positive regulation of cellular component biogenesis GO:0044089 80 0.029
stem cell maintenance GO:0019827 67 0.029
Mouse
regulation of cell morphogenesis involved in differentiation GO:0010769 61 0.029
establishment of tissue polarity GO:0007164 87 0.029
phagocytosis GO:0006909 215 0.029
single organism intracellular transport GO:1902582 207 0.029
protein complex biogenesis GO:0070271 201 0.028
appendage morphogenesis GO:0035107 397 0.028
cellular protein modification process GO:0006464 438 0.028
anterior posterior pattern specification GO:0009952 136 0.028
mrna processing GO:0006397 104 0.028
appendage development GO:0048736 401 0.028
positive regulation of cell communication GO:0010647 250 0.028
cytoplasmic transport GO:0016482 130 0.027
response to ecdysone GO:0035075 34 0.027
embryo development ending in birth or egg hatching GO:0009792 152 0.027
regulation of multi organism process GO:0043900 131 0.027
rna splicing via transesterification reactions GO:0000375 73 0.027
response to other organism GO:0051707 293 0.027
larval development GO:0002164 104 0.027
positive regulation of cellular amine metabolic process GO:0033240 0 0.027
oxidoreduction coenzyme metabolic process GO:0006733 2 0.027
determination of adult lifespan GO:0008340 137 0.026
response to biotic stimulus GO:0009607 294 0.026
nucleoside triphosphate catabolic process GO:0009143 108 0.026
telencephalon development GO:0021537 2 0.026
nucleotide metabolic process GO:0009117 161 0.026
positive regulation of cell migration GO:0030335 2 0.026
purine nucleoside triphosphate catabolic process GO:0009146 108 0.026
endodermal cell differentiation GO:0035987 3 0.025
apoptotic signaling pathway GO:0097190 27 0.025
leg disc morphogenesis GO:0007478 80 0.025
leg disc development GO:0035218 92 0.025
respiratory system development GO:0060541 213 0.024
positive regulation of phosphate metabolic process GO:0045937 139 0.024
gastrulation GO:0007369 70 0.024
mitotic nuclear division GO:0007067 213 0.024
regulation of cellular component size GO:0032535 98 0.024
positive regulation of programmed cell death GO:0043068 62 0.024
myofibril assembly GO:0030239 36 0.023
purine ribonucleotide catabolic process GO:0009154 109 0.023
regulation of molecular function GO:0065009 217 0.023
purine nucleotide catabolic process GO:0006195 109 0.022
regulation of protein metabolic process GO:0051246 256 0.022
regulation of immune response GO:0050776 118 0.022
purine ribonucleoside triphosphate catabolic process GO:0009207 108 0.022
regulation of axonogenesis GO:0050770 32 0.022
regulation of autophagy GO:0010506 62 0.022
regulation of response to external stimulus GO:0032101 115 0.022
glycosyl compound metabolic process GO:1901657 127 0.021
chemotaxis GO:0006935 249 0.021
protein transport GO:0015031 155 0.021
posttranscriptional gene silencing GO:0016441 46 0.021
purine ribonucleoside metabolic process GO:0046128 127 0.021
regulation of cellular protein metabolic process GO:0032268 243 0.021
organic acid metabolic process GO:0006082 103 0.020
ribonucleoside triphosphate catabolic process GO:0009203 108 0.020
regulation of mrna splicing via spliceosome GO:0048024 64 0.020
nucleobase containing small molecule metabolic process GO:0055086 174 0.020
chromatin remodeling GO:0006338 72 0.020
snrna metabolic process GO:0016073 14 0.020
negative regulation of cellular component organization GO:0051129 108 0.020
regulation of actin polymerization or depolymerization GO:0008064 27 0.019
neuron maturation GO:0042551 31 0.019
protein phosphorylation GO:0006468 169 0.019
phosphorylation GO:0016310 294 0.019
response to external biotic stimulus GO:0043207 293 0.019
heterocycle catabolic process GO:0046700 166 0.019
protein modification process GO:0036211 438 0.019
cellular macromolecule catabolic process GO:0044265 136 0.019
response to ketone GO:1901654 34 0.019
dna damage checkpoint GO:0000077 78 0.019
actin cytoskeleton organization GO:0030036 206 0.018
cardiovascular system development GO:0072358 82 0.018
hemopoiesis GO:0030097 46 0.018
myotube cell development GO:0014904 3 0.018
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 116 0.018
positive regulation of organelle organization GO:0010638 65 0.018
dendrite morphogenesis GO:0048813 199 0.018
gonad development GO:0008406 50 0.018
positive regulation of cell death GO:0010942 69 0.018
peptidyl lysine trimethylation GO:0018023 6 0.018
axon guidance GO:0007411 233 0.018
ribonucleotide catabolic process GO:0009261 109 0.018
ribonucleoside catabolic process GO:0042454 112 0.018
negative regulation of transcription from rna polymerase ii promoter GO:0000122 119 0.018
mapk cascade GO:0000165 107 0.017
nucleobase containing compound catabolic process GO:0034655 165 0.017
actin polymerization or depolymerization GO:0008154 31 0.017
regulation of mrna metabolic process GO:1903311 72 0.017
golgi organization GO:0007030 66 0.017
regulation of anatomical structure size GO:0090066 163 0.017
regulation of apoptotic process GO:0042981 130 0.017
positive regulation of cell differentiation GO:0045597 64 0.017
carbohydrate derivative catabolic process GO:1901136 118 0.017
innate immune response GO:0045087 144 0.017
regionalization GO:0003002 416 0.017
negative regulation of cell proliferation GO:0008285 69 0.016
cellular macromolecular complex assembly GO:0034622 153 0.016
protein complex assembly GO:0006461 200 0.016
regulation of phosphate metabolic process GO:0019220 210 0.016
response to lipopolysaccharide GO:0032496 4 0.016
camera type eye morphogenesis GO:0048593 2 0.016
Zebrafish
cell fate determination GO:0001709 91 0.016
signal transduction by phosphorylation GO:0023014 107 0.016
cell cycle checkpoint GO:0000075 95 0.016
glial cell differentiation GO:0010001 35 0.016
positive regulation of intracellular signal transduction GO:1902533 116 0.016
regulation of organ morphogenesis GO:2000027 78 0.015
regulation of antimicrobial peptide biosynthetic process GO:0002805 38 0.015
cation homeostasis GO:0055080 51 0.015
positive regulation of cellular amino acid metabolic process GO:0045764 0 0.015
single organism carbohydrate metabolic process GO:0044723 72 0.015
positive regulation of immune response GO:0050778 63 0.015
regulation of mitotic cell cycle phase transition GO:1901990 130 0.015
purine containing compound metabolic process GO:0072521 155 0.015
regulation of cellular catabolic process GO:0031329 157 0.015
eye morphogenesis GO:0048592 260 0.014
Zebrafish
nitrogen compound transport GO:0071705 85 0.014
digestive tract development GO:0048565 149 0.014
negative regulation of cell communication GO:0010648 223 0.014
positive regulation of mapk cascade GO:0043410 63 0.014
purine ribonucleotide metabolic process GO:0009150 145 0.014
regulation of immune effector process GO:0002697 52 0.014
morphogenesis of a polarized epithelium GO:0001738 93 0.014
positive regulation of apoptotic signaling pathway GO:2001235 4 0.014
sensory organ morphogenesis GO:0090596 260 0.014
Zebrafish
mrna splicing via spliceosome GO:0000398 73 0.014
regulation of gene silencing GO:0060968 63 0.014
regulation of wnt signaling pathway GO:0030111 68 0.014
positive regulation of hydrolase activity GO:0051345 78 0.014
regulation of protein modification process GO:0031399 112 0.014
purine containing compound catabolic process GO:0072523 112 0.014
defense response to other organism GO:0098542 225 0.014
negative regulation of gene expression epigenetic GO:0045814 77 0.014
cellular response to hormone stimulus GO:0032870 44 0.014
single organism behavior GO:0044708 391 0.014
striated muscle myosin thick filament assembly GO:0071688 3 0.014
nucleoside triphosphate metabolic process GO:0009141 120 0.014
central nervous system development GO:0007417 201 0.014
regulation of endopeptidase activity GO:0052548 36 0.014
syncytium formation GO:0006949 43 0.013
cellular response to lipopolysaccharide GO:0071222 3 0.013
cellular nitrogen compound catabolic process GO:0044270 165 0.013
intracellular signal transduction GO:0035556 300 0.013
positive regulation of phosphorus metabolic process GO:0010562 139 0.013
nucleotide catabolic process GO:0009166 109 0.013
rna localization GO:0006403 115 0.013
regulation of cell substrate adhesion GO:0010810 2 0.013
glycosyl compound catabolic process GO:1901658 112 0.013
cellular homeostasis GO:0019725 80 0.013
dna packaging GO:0006323 91 0.013
chromatin assembly or disassembly GO:0006333 52 0.013
positive regulation of protein modification process GO:0031401 58 0.013
regulation of phosphorus metabolic process GO:0051174 210 0.013
regulation of chromosome organization GO:0033044 64 0.013
nucleoside metabolic process GO:0009116 127 0.013
positive regulation of cellular protein metabolic process GO:0032270 118 0.013
regulation of response to stress GO:0080134 200 0.013
mesenchymal cell development GO:0014031 1 0.013
carbohydrate derivative metabolic process GO:1901135 217 0.013
cellular response to external stimulus GO:0071496 66 0.013
cellular response to organic substance GO:0071310 132 0.013
endomembrane system organization GO:0010256 119 0.013
epithelial tube morphogenesis GO:0060562 88 0.013
cell cycle phase transition GO:0044770 140 0.013
carbohydrate metabolic process GO:0005975 82 0.013
notch signaling pathway GO:0007219 120 0.013
regulation of intracellular signal transduction GO:1902531 236 0.013
regulation of nuclear division GO:0051783 58 0.013
gene silencing by rna GO:0031047 57 0.013
peptidyl lysine modification GO:0018205 57 0.012
positive regulation of gtpase activity GO:0043547 43 0.012
aromatic compound catabolic process GO:0019439 166 0.012
actomyosin structure organization GO:0031032 56 0.012
regulation of cysteine type endopeptidase activity GO:2000116 27 0.012
negative regulation of response to stimulus GO:0048585 258 0.012
response to abiotic stimulus GO:0009628 341 0.012
mrna metabolic process GO:0016071 124 0.012
purine nucleoside catabolic process GO:0006152 112 0.012
open tracheal system development GO:0007424 204 0.012
regulation of humoral immune response GO:0002920 51 0.012
actin filament based process GO:0030029 220 0.012
autophagic vacuole assembly GO:0000045 2 0.012
macromolecule methylation GO:0043414 45 0.012
protein dna complex assembly GO:0065004 63 0.012
small gtpase mediated signal transduction GO:0007264 88 0.012
negative regulation of cell cycle GO:0045786 116 0.012
response to nutrient levels GO:0031667 114 0.012
single organism catabolic process GO:0044712 228 0.012
regulation of chromatin modification GO:1903308 28 0.012
digestive system development GO:0055123 149 0.012
positive regulation of catabolic process GO:0009896 105 0.011
defense response to bacterium GO:0042742 178 0.011
protein processing GO:0016485 68 0.011
extrinsic apoptotic signaling pathway GO:0097191 1 0.011
hematopoietic or lymphoid organ development GO:0048534 57 0.011
Zebrafish
cellular response to nutrient levels GO:0031669 62 0.011
apoptotic process GO:0006915 159 0.011
cellular ketone metabolic process GO:0042180 24 0.011
cellular response to lipid GO:0071396 20 0.011
regulation of meiosis GO:0040020 3 0.011
regulation of hydrolase activity GO:0051336 97 0.011
regulation of dna templated transcription in response to stress GO:0043620 4 0.011
regulation of dna templated transcription elongation GO:0032784 17 0.011
internal peptidyl lysine acetylation GO:0018393 38 0.011
compound eye morphogenesis GO:0001745 249 0.011
establishment of planar polarity GO:0001736 87 0.011
positive regulation of cellular catabolic process GO:0031331 95 0.011
neural retina development GO:0003407 4 0.011
Zebrafish
mitotic g2 m transition checkpoint GO:0044818 70 0.011
anatomical structure homeostasis GO:0060249 97 0.011
extracellular matrix assembly GO:0085029 13 0.011
positive regulation of protein tyrosine kinase activity GO:0061098 4 0.011
ribonucleotide metabolic process GO:0009259 145 0.011
humoral immune response GO:0006959 117 0.010
posttranscriptional gene silencing by rna GO:0035194 45 0.010
hindbrain development GO:0030902 2 0.010
morphogenesis of a branching structure GO:0001763 45 0.010
positive regulation of cell cycle process GO:0090068 28 0.010
compound eye development GO:0048749 307 0.010
guanosine containing compound metabolic process GO:1901068 74 0.010
nucleoside phosphate catabolic process GO:1901292 110 0.010
macromolecule catabolic process GO:0009057 161 0.010
gonad morphogenesis GO:0035262 7 0.010
regulation of nucleotide metabolic process GO:0006140 62 0.010
snrna 3 end processing GO:0034472 14 0.010
protein secretion GO:0009306 45 0.010
immune system development GO:0002520 57 0.010
Zebrafish
axonogenesis GO:0007409 290 0.010
regulation of cell cycle phase transition GO:1901987 130 0.010

MED24 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.071
nervous system disease DOID:863 0 0.030