Drosophila melanogaster

25 known processes

Npc2e (Dmel_CG31410)

Niemann-Pick type C-2e

(Aliases: CG31410,npc2e,CG3928,Dmel\CG31410)

Npc2e biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
organonitrogen compound metabolic process GO:1901564 318 0.045
small molecule metabolic process GO:0044281 305 0.043
Fly
cell cell signaling involved in cell fate commitment GO:0045168 210 0.036
response to abiotic stimulus GO:0009628 341 0.035
catabolic process GO:0009056 409 0.035
body morphogenesis GO:0010171 2 0.032
cellular catabolic process GO:0044248 372 0.032
appendage development GO:0048736 401 0.030
vesicle mediated transport GO:0016192 381 0.030
regionalization GO:0003002 416 0.030
carboxylic acid metabolic process GO:0019752 92 0.029
appendage morphogenesis GO:0035107 397 0.029
oxoacid metabolic process GO:0043436 103 0.029
organic substance catabolic process GO:1901575 308 0.029
wing disc morphogenesis GO:0007472 344 0.029
lateral inhibition GO:0046331 206 0.029
imaginal disc derived appendage morphogenesis GO:0035114 395 0.028
protein modification process GO:0036211 438 0.028
defense response GO:0006952 300 0.028
imaginal disc derived appendage development GO:0048737 399 0.028
single organism biosynthetic process GO:0044711 206 0.028
Fly
organic acid metabolic process GO:0006082 103 0.028
post embryonic appendage morphogenesis GO:0035120 385 0.028
positive regulation of response to stimulus GO:0048584 323 0.027
imaginal disc derived wing morphogenesis GO:0007476 337 0.026
cellular amino acid metabolic process GO:0006520 61 0.026
neurological system process GO:0050877 358 0.026
phagocytosis GO:0006909 215 0.026
negative regulation of gene expression GO:0010629 387 0.025
negative regulation of cellular metabolic process GO:0031324 382 0.025
camera type eye development GO:0043010 4 0.025
response to lipopolysaccharide GO:0032496 4 0.025
single organism behavior GO:0044708 391 0.025
regulation of multicellular organismal development GO:2000026 414 0.025
benzene containing compound metabolic process GO:0042537 3 0.025
xenobiotic catabolic process GO:0042178 1 0.024
cellular protein modification process GO:0006464 438 0.024
endocytosis GO:0006897 310 0.024
single organism catabolic process GO:0044712 228 0.024
nuclear division GO:0000280 332 0.024
response to other organism GO:0051707 293 0.023
intracellular signal transduction GO:0035556 300 0.023
positive regulation of nitrogen compound metabolic process GO:0051173 354 0.023
epithelial cell development GO:0002064 274 0.023
forebrain development GO:0030900 2 0.023
regulation of cellular amine metabolic process GO:0033238 3 0.023
positive regulation of cell communication GO:0010647 250 0.022
regulation of localization GO:0032879 275 0.022
negative regulation of nitrogen compound metabolic process GO:0051172 265 0.022
activation of innate immune response GO:0002218 4 0.022
carbohydrate derivative metabolic process GO:1901135 217 0.022
response to biotic stimulus GO:0009607 294 0.022
growth GO:0040007 359 0.022
hormone catabolic process GO:0042447 3 0.022
positive regulation of macromolecule metabolic process GO:0010604 405 0.022
positive regulation of cellular biosynthetic process GO:0031328 316 0.022
gland development GO:0048732 191 0.021
transcription from rna polymerase ii promoter GO:0006366 368 0.021
l amino acid import GO:0043092 2 0.021
steroid catabolic process GO:0006706 1 0.021
response to organic substance GO:0010033 284 0.021
organelle fission GO:0048285 340 0.021
positive regulation of nucleobase containing compound metabolic process GO:0045935 332 0.021
epithelial cell differentiation GO:0030855 322 0.021
immune system process GO:0002376 347 0.020
Fly
compound eye development GO:0048749 307 0.020
proteolysis GO:0006508 192 0.020
positive regulation of signal transduction GO:0009967 223 0.020
establishment of localization in cell GO:0051649 402 0.020
regulation of cellular ketone metabolic process GO:0010565 3 0.020
taxis GO:0042330 304 0.020
positive regulation of signaling GO:0023056 243 0.020
cell death GO:0008219 279 0.020
adult behavior GO:0030534 137 0.020
developmental growth GO:0048589 280 0.020
phosphorylation GO:0016310 294 0.020
salivary gland development GO:0007431 162 0.020
cellular response to ethanol GO:0071361 4 0.020
eye development GO:0001654 323 0.020
sterol homeostasis GO:0055092 4 0.020
Fly
regulation of cell cycle GO:0051726 291 0.020
columnar cuboidal epithelial cell development GO:0002066 249 0.020
regulation of cellular amino acid metabolic process GO:0006521 0 0.020
tissue morphogenesis GO:0048729 297 0.020
cellular ketone metabolic process GO:0042180 24 0.019
Fly
columnar cuboidal epithelial cell differentiation GO:0002065 256 0.019
kidney development GO:0001822 3 0.019
morphogenesis of an epithelium GO:0002009 276 0.019
defense response to other organism GO:0098542 225 0.019
amine metabolic process GO:0009308 12 0.019
organic substance transport GO:0071702 257 0.019
Fly
cholesterol homeostasis GO:0042632 3 0.019
death GO:0016265 284 0.019
negative regulation of macromolecule biosynthetic process GO:0010558 270 0.019
response to oxygen containing compound GO:1901700 200 0.019
negative regulation of signal transduction GO:0009968 206 0.019
gland morphogenesis GO:0022612 145 0.019
negative regulation of nucleic acid templated transcription GO:1903507 240 0.019
response to external biotic stimulus GO:0043207 293 0.019
regulation of intracellular signal transduction GO:1902531 236 0.019
immune response activating signal transduction GO:0002757 2 0.019
positive regulation of nucleic acid templated transcription GO:1903508 266 0.018
connective tissue development GO:0061448 3 0.018
regulation of cell differentiation GO:0045595 302 0.018
homeostatic process GO:0042592 199 0.018
Fly
negative regulation of cell communication GO:0010648 223 0.018
cellular amine metabolic process GO:0044106 12 0.018
exocrine system development GO:0035272 162 0.018
salivary gland morphogenesis GO:0007435 145 0.018
cellular component assembly involved in morphogenesis GO:0010927 151 0.018
negative regulation of biosynthetic process GO:0009890 277 0.018
ovarian follicle cell development GO:0030707 248 0.018
telencephalon development GO:0021537 2 0.018
compound eye morphogenesis GO:0001745 249 0.018
negative regulation of cellular biosynthetic process GO:0031327 277 0.018
regulation of molecular function GO:0065009 217 0.018
aromatic compound catabolic process GO:0019439 166 0.018
positive regulation of rna biosynthetic process GO:1902680 266 0.018
positive regulation of macromolecule biosynthetic process GO:0010557 283 0.018
positive regulation of cell motility GO:2000147 3 0.018
protein localization GO:0008104 284 0.018
l glutamate import GO:0051938 1 0.017
segmentation GO:0035282 207 0.017
positive regulation of cell migration GO:0030335 2 0.017
cell proliferation GO:0008283 299 0.017
positive regulation of biosynthetic process GO:0009891 316 0.017
macromolecule catabolic process GO:0009057 161 0.017
regulation of transcription from rna polymerase ii promoter GO:0006357 378 0.017
regulation of epithelial cell proliferation GO:0050678 4 0.017
ion transport GO:0006811 145 0.017
heterocycle catabolic process GO:0046700 166 0.017
regulation of phosphorus metabolic process GO:0051174 210 0.017
negative regulation of signaling GO:0023057 219 0.017
eye morphogenesis GO:0048592 260 0.017
response to monosaccharide GO:0034284 4 0.017
positive regulation of gene expression GO:0010628 290 0.017
programmed cell death GO:0012501 257 0.017
regulation of immune system process GO:0002682 176 0.017
androgen metabolic process GO:0008209 1 0.017
organophosphate metabolic process GO:0019637 195 0.017
positive regulation of rna metabolic process GO:0051254 271 0.017
sensory organ morphogenesis GO:0090596 260 0.017
organic cyclic compound catabolic process GO:1901361 168 0.017
developmental programmed cell death GO:0010623 138 0.017
sensory perception GO:0007600 196 0.017
immune response GO:0006955 246 0.017
Fly
vitamin metabolic process GO:0006766 2 0.016
mating GO:0007618 120 0.016
negative regulation of response to stimulus GO:0048585 258 0.016
negative regulation of rna metabolic process GO:0051253 251 0.016
positive regulation of transcription dna templated GO:0045893 266 0.016
tube development GO:0035295 244 0.016
multi organism behavior GO:0051705 175 0.016
response to hexose GO:0009746 3 0.016
negative regulation of rna biosynthetic process GO:1902679 240 0.016
negative regulation of developmental process GO:0051093 201 0.016
open tracheal system development GO:0007424 204 0.016
negative regulation of cellular macromolecule biosynthetic process GO:2000113 267 0.016
response to organophosphorus GO:0046683 2 0.016
intracellular transport GO:0046907 228 0.016
response to glucose GO:0009749 2 0.016
negative regulation of nucleobase containing compound metabolic process GO:0045934 261 0.016
detection of stimulus GO:0051606 156 0.016
estrogen metabolic process GO:0008210 1 0.016
response to radiation GO:0009314 155 0.016
fat soluble vitamin metabolic process GO:0006775 1 0.016
limb development GO:0060173 1 0.016
chromosome organization GO:0051276 360 0.016
regulation of cellular component biogenesis GO:0044087 201 0.016
regulation of cellular protein metabolic process GO:0032268 243 0.016
cellular response to chemical stimulus GO:0070887 199 0.015
synaptic transmission GO:0007268 288 0.015
regulation of transport GO:0051049 181 0.015
respiratory system development GO:0060541 213 0.015
regulation of protein metabolic process GO:0051246 256 0.015
regulation of phosphate metabolic process GO:0019220 210 0.015
regulation of catalytic activity GO:0050790 185 0.015
chemotaxis GO:0006935 249 0.015
negative regulation of transcription dna templated GO:0045892 237 0.015
response to nutrient levels GO:0031667 114 0.015
mitotic nuclear division GO:0007067 213 0.015
nucleobase containing small molecule metabolic process GO:0055086 174 0.015
small gtpase mediated signal transduction GO:0007264 88 0.015
pigmentation GO:0043473 75 0.015
cellular macromolecule catabolic process GO:0044265 136 0.015
immune response regulating signaling pathway GO:0002764 2 0.015
cellular response to dna damage stimulus GO:0006974 223 0.015
protein hydroxylation GO:0018126 1 0.015
cell cycle phase transition GO:0044770 140 0.015
mitotic cell cycle phase transition GO:0044772 138 0.015
cellular nitrogen compound catabolic process GO:0044270 165 0.015
camera type eye morphogenesis GO:0048593 2 0.015
retina development in camera type eye GO:0060041 4 0.015
response to bacterium GO:0009617 198 0.015
dorsal ventral pattern formation GO:0009953 133 0.015
regulation of multi organism process GO:0043900 131 0.015
regulation of response to stress GO:0080134 200 0.015
hindbrain development GO:0030902 2 0.015
neuropeptide signaling pathway GO:0007218 45 0.015
regulation of catabolic process GO:0009894 170 0.014
regulation of developmental growth GO:0048638 174 0.014
regulation of mitotic cell cycle GO:0007346 190 0.014
single organism intracellular transport GO:1902582 207 0.014
regulation of cellular catabolic process GO:0031329 157 0.014
negative regulation of multicellular organismal process GO:0051241 142 0.014
lipid metabolic process GO:0006629 121 0.014
Fly
regulation of cell development GO:0060284 215 0.014
enzyme linked receptor protein signaling pathway GO:0007167 179 0.014
developmental maturation GO:0021700 172 0.014
peptide metabolic process GO:0006518 80 0.014
eggshell formation GO:0030703 105 0.014
mesenchymal cell differentiation GO:0048762 1 0.014
nephron development GO:0072006 3 0.014
regulation of cell cycle phase transition GO:1901987 130 0.014
ras protein signal transduction GO:0007265 88 0.014
neutral lipid biosynthetic process GO:0046460 2 0.014
defense response to bacterium GO:0042742 178 0.014
regulation of cell cycle process GO:0010564 181 0.014
cellular amide metabolic process GO:0043603 80 0.014
nucleoside phosphate metabolic process GO:0006753 162 0.014
chromosome segregation GO:0007059 157 0.014
tube morphogenesis GO:0035239 191 0.014
blastoderm segmentation GO:0007350 159 0.014
gene silencing GO:0016458 138 0.014
mesenchymal cell development GO:0014031 1 0.014
embryonic pattern specification GO:0009880 174 0.014
regulation of mitotic cell cycle phase transition GO:1901990 130 0.014
neuron projection guidance GO:0097485 241 0.014
axis specification GO:0009798 167 0.014
organelle assembly GO:0070925 198 0.014
phosphate ion transport GO:0006817 4 0.013
vitamin biosynthetic process GO:0009110 1 0.013
organonitrogen compound biosynthetic process GO:1901566 117 0.013
nucleobase containing compound catabolic process GO:0034655 165 0.013
rna processing GO:0006396 147 0.013
positive regulation of cellular amine metabolic process GO:0033240 0 0.013
regulation of epithelial cell differentiation GO:0030856 4 0.013
triglyceride catabolic process GO:0019433 3 0.013
regulation of cell death GO:0010941 173 0.013
developmental pigmentation GO:0048066 68 0.013
cellular macromolecule localization GO:0070727 220 0.013
transmembrane transport GO:0055085 139 0.013
cellular response to molecule of bacterial origin GO:0071219 3 0.013
response to light stimulus GO:0009416 124 0.013
leg disc development GO:0035218 92 0.013
spermatogenesis GO:0007283 200 0.013
positive regulation of transcription from rna polymerase ii promoter GO:0045944 204 0.013
kidney epithelium development GO:0072073 3 0.013
multicellular organismal aging GO:0010259 140 0.013
chorion containing eggshell formation GO:0007304 105 0.013
regulation of synapse structure and activity GO:0050803 128 0.013
acylglycerol biosynthetic process GO:0046463 2 0.013
male gamete generation GO:0048232 201 0.013
cell division GO:0051301 248 0.013
regulation of nervous system development GO:0051960 248 0.013
anion homeostasis GO:0055081 3 0.013
macromolecular complex assembly GO:0065003 256 0.013
negative regulation of cell differentiation GO:0045596 143 0.013
carbohydrate metabolic process GO:0005975 82 0.013
humoral immune response GO:0006959 117 0.013
Fly
antimicrobial humoral response GO:0019730 99 0.013
glycerolipid catabolic process GO:0046503 3 0.013
cell motility GO:0048870 251 0.013
sensory perception of chemical stimulus GO:0007606 116 0.013
regulation of anatomical structure morphogenesis GO:0022603 242 0.013
actin cytoskeleton organization GO:0030036 206 0.013
triglyceride biosynthetic process GO:0019432 2 0.013
positive regulation of cellular amino acid metabolic process GO:0045764 0 0.013
locomotory behavior GO:0007626 176 0.013
purine nucleotide metabolic process GO:0006163 146 0.013
ion transmembrane transport GO:0034220 122 0.013
response to copper ion GO:0046688 4 0.013
nephron epithelium development GO:0072009 3 0.013
posttranscriptional regulation of gene expression GO:0010608 145 0.013
cellular response to lipopolysaccharide GO:0071222 3 0.013
chaeta development GO:0022416 97 0.013
skeletal muscle fiber development GO:0048741 3 0.013
innate immune response GO:0045087 144 0.013
Fly
nucleotide metabolic process GO:0009117 161 0.013
actin filament based process GO:0030029 220 0.013
fat soluble vitamin biosynthetic process GO:0042362 1 0.013
limb morphogenesis GO:0035108 1 0.012
purine ribonucleotide metabolic process GO:0009150 145 0.012
protein transport GO:0015031 155 0.012
negative regulation of cell cycle process GO:0010948 109 0.012
regulation of gene expression epigenetic GO:0040029 128 0.012
kidney morphogenesis GO:0060993 3 0.012
purine containing compound metabolic process GO:0072521 155 0.012
regulation of notch signaling pathway GO:0008593 100 0.012
axon development GO:0061564 297 0.012
nephron tubule development GO:0072080 3 0.012
regulation of immune response GO:0050776 118 0.012
monocarboxylic acid transport GO:0015718 3 0.012
axon guidance GO:0007411 233 0.012
spindle organization GO:0007051 253 0.012
pattern recognition receptor signaling pathway GO:0002221 2 0.012
apoptotic process GO:0006915 159 0.012
salivary gland cell autophagic cell death GO:0035071 83 0.012
regulation of programmed cell death GO:0043067 152 0.012
sodium dependent phosphate transport GO:0044341 2 0.012
photoreceptor cell differentiation GO:0046530 170 0.012
dendrite development GO:0016358 204 0.012
regulation of response to external stimulus GO:0032101 115 0.012
tissue death GO:0016271 102 0.012
chromatin organization GO:0006325 207 0.012
cellular protein localization GO:0034613 160 0.012
single organism cellular localization GO:1902580 180 0.012
pigment metabolic process GO:0042440 84 0.012
histolysis GO:0007559 102 0.012
establishment of protein localization GO:0045184 163 0.012
ethanolamine containing compound metabolic process GO:0042439 4 0.012
organonitrogen compound catabolic process GO:1901565 128 0.012
positive regulation of catabolic process GO:0009896 105 0.012
purine ribonucleoside metabolic process GO:0046128 127 0.012
detection of abiotic stimulus GO:0009582 66 0.012
notch signaling pathway GO:0007219 120 0.012
signal transduction by phosphorylation GO:0023014 107 0.012
peptidyl amino acid modification GO:0018193 105 0.012
regulation of organelle organization GO:0033043 196 0.012
cation transport GO:0006812 110 0.012
synapse organization GO:0050808 196 0.012
imaginal disc pattern formation GO:0007447 91 0.012
autophagic cell death GO:0048102 83 0.012
sensory perception of salty taste GO:0050914 3 0.012
cell migration GO:0016477 238 0.012
ribonucleotide metabolic process GO:0009259 145 0.012
sister chromatid segregation GO:0000819 92 0.012
protein phosphorylation GO:0006468 169 0.012
positive regulation of phosphorus metabolic process GO:0010562 139 0.012
cytoplasmic transport GO:0016482 130 0.012
mrna metabolic process GO:0016071 124 0.012
central nervous system development GO:0007417 201 0.012
axonogenesis GO:0007409 290 0.012
positive regulation of lipid storage GO:0010884 4 0.012
cellular response to hexose stimulus GO:0071331 1 0.012
hematopoietic progenitor cell differentiation GO:0002244 1 0.012
positive regulation of catalytic activity GO:0043085 118 0.012
innate immune response activating signal transduction GO:0002758 2 0.012
sensory perception of pain GO:0019233 4 0.012
salt aversion GO:0035199 3 0.012
regulation of i kappab kinase nf kappab signaling GO:0043122 2 0.012
nucleoside metabolic process GO:0009116 127 0.012
positive regulation of multicellular organismal process GO:0051240 143 0.012
positive regulation of intracellular signal transduction GO:1902533 116 0.012
acetate ester metabolic process GO:1900619 2 0.011
polyol biosynthetic process GO:0046173 3 0.011
response to extracellular stimulus GO:0009991 116 0.011
establishment or maintenance of cell polarity GO:0007163 167 0.011
negative regulation of cell cycle GO:0045786 116 0.011
response to endogenous stimulus GO:0009719 119 0.011
cellular response to carbohydrate stimulus GO:0071322 4 0.011
localization of cell GO:0051674 257 0.011
salivary gland histolysis GO:0035070 88 0.011
imaginal disc derived leg morphogenesis GO:0007480 80 0.011
organophosphate catabolic process GO:0046434 112 0.011
regulation of cell substrate adhesion GO:0010810 2 0.011
somatic muscle development GO:0007525 66 0.011
multi multicellular organism process GO:0044706 123 0.011
regulation of lipid transport GO:0032368 3 0.011
sensory perception of smell GO:0007608 80 0.011
acetylcholine metabolic process GO:0008291 2 0.011
dendrite morphogenesis GO:0048813 199 0.011
cellular response to biotic stimulus GO:0071216 4 0.011
pigment metabolic process involved in pigmentation GO:0043474 33 0.011
ribonucleoside metabolic process GO:0009119 127 0.011
regulation of cellular response to stress GO:0080135 89 0.011
spinal cord development GO:0021510 1 0.011
embryonic development via the syncytial blastoderm GO:0001700 148 0.011
eye photoreceptor cell differentiation GO:0001754 145 0.011
response to pain GO:0048265 3 0.011
regulation of phosphorylation GO:0042325 147 0.011
mitotic dna integrity checkpoint GO:0044774 75 0.011
cuticle development GO:0042335 86 0.011
anterior posterior axis specification embryo GO:0008595 103 0.011
cell maturation GO:0048469 144 0.011
synapse assembly GO:0007416 143 0.011
molting cycle chitin based cuticle GO:0007591 56 0.011
cell cycle checkpoint GO:0000075 95 0.011
compound eye photoreceptor cell differentiation GO:0001751 140 0.011
wnt signaling pathway GO:0016055 98 0.011
establishment of tissue polarity GO:0007164 87 0.011
pyridine containing compound metabolic process GO:0072524 3 0.011
positive regulation of peptidyl tyrosine phosphorylation GO:0050731 4 0.011
cellular response to organic substance GO:0071310 132 0.011
protein catabolic process GO:0030163 101 0.011
mitotic spindle organization GO:0007052 220 0.011
cellular homeostasis GO:0019725 80 0.011
wound healing GO:0042060 75 0.011
Fly
regulation of cellular localization GO:0060341 136 0.011
detection of external stimulus GO:0009581 66 0.011
eye pigmentation GO:0048069 43 0.011
secondary metabolic process GO:0019748 75 0.011
membrane depolarization GO:0051899 4 0.011
cellular lipid metabolic process GO:0044255 83 0.011
cellular response to monosaccharide stimulus GO:0071326 2 0.011
response to alcohol GO:0097305 95 0.011
regulation of response to biotic stimulus GO:0002831 63 0.011
ameboidal type cell migration GO:0001667 151 0.011
regulation of synapse assembly GO:0051963 94 0.011
photoreceptor cell development GO:0042461 96 0.011
regulation of growth GO:0040008 233 0.011
imaginal disc derived wing vein specification GO:0007474 48 0.011
autophagy GO:0006914 108 0.011
leg disc morphogenesis GO:0007478 80 0.011
anterior posterior pattern specification GO:0009952 136 0.011
positive regulation of phosphate metabolic process GO:0045937 139 0.011
eggshell chorion assembly GO:0007306 66 0.011
purine nucleoside metabolic process GO:0042278 127 0.010
glutathione metabolic process GO:0006749 37 0.010
acylglycerol catabolic process GO:0046464 3 0.010
mapk cascade GO:0000165 107 0.010
cholesterol transport GO:0030301 2 0.010
negative regulation of nervous system development GO:0051961 92 0.010
long chain fatty acid metabolic process GO:0001676 3 0.010
carbohydrate derivative catabolic process GO:1901136 118 0.010
digestive tract development GO:0048565 149 0.010
regulation of apoptotic process GO:0042981 130 0.010
oxidoreduction coenzyme metabolic process GO:0006733 2 0.010
positive regulation of molecular function GO:0044093 136 0.010
positive regulation of transport GO:0051050 92 0.010
digestive tract morphogenesis GO:0048546 127 0.010
cell cycle arrest GO:0007050 4 0.010
nicotinamide nucleotide metabolic process GO:0046496 2 0.010
regulation of mapk cascade GO:0043408 92 0.010
endomembrane system organization GO:0010256 119 0.010
proteolysis involved in cellular protein catabolic process GO:0051603 83 0.010
tripartite regional subdivision GO:0007351 103 0.010
cellular modified amino acid metabolic process GO:0006575 45 0.010
single organism carbohydrate metabolic process GO:0044723 72 0.010
dna integrity checkpoint GO:0031570 81 0.010
nucleoside phosphate catabolic process GO:1901292 110 0.010
phosphatidic acid metabolic process GO:0046473 1 0.010
regulation of synapse organization GO:0050807 110 0.010
response to ethanol GO:0045471 59 0.010
mitotic sister chromatid segregation GO:0000070 87 0.010
behavioral response to pain GO:0048266 3 0.010
drinking behavior GO:0042756 2 0.010
protein complex biogenesis GO:0070271 201 0.010
mrna processing GO:0006397 104 0.010
g protein coupled receptor signaling pathway GO:0007186 136 0.010
ribose phosphate metabolic process GO:0019693 145 0.010
organelle localization GO:0051640 148 0.010
ribonucleoside catabolic process GO:0042454 112 0.010
inter male aggressive behavior GO:0002121 60 0.010
purine nucleotide catabolic process GO:0006195 109 0.010
embryonic morphogenesis GO:0048598 206 0.010
positive regulation of developmental process GO:0051094 143 0.010
sulfur compound metabolic process GO:0006790 59 0.010
extrinsic apoptotic signaling pathway GO:0097191 1 0.010
muscle structure development GO:0061061 224 0.010
protein complex assembly GO:0006461 200 0.010
regulation of hydrolase activity GO:0051336 97 0.010
protein processing GO:0016485 68 0.010

Npc2e disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.036
nervous system disease DOID:863 0 0.019
disease of metabolism DOID:0014667 0 0.018
inherited metabolic disorder DOID:655 0 0.018
cardiovascular system disease DOID:1287 0 0.016
disease of cellular proliferation DOID:14566 0 0.013
urinary system disease DOID:18 0 0.013
sensory system disease DOID:0050155 0 0.013
musculoskeletal system disease DOID:17 0 0.013
eye and adnexa disease DOID:1492 0 0.012
eye disease DOID:5614 0 0.012
diabetes mellitus DOID:9351 0 0.012
type 2 diabetes mellitus DOID:9352 0 0.012
carbohydrate metabolism disease DOID:0050013 0 0.012
glucose metabolism disease DOID:4194 0 0.012
acquired metabolic disease DOID:0060158 0 0.012
kidney disease DOID:557 0 0.012
hypertension DOID:10763 0 0.011
artery disease DOID:0050828 0 0.011
vascular disease DOID:178 0 0.011
cancer DOID:162 0 0.011
organ system cancer DOID:0050686 0 0.011