Drosophila melanogaster

15 known processes

cdc2c (Dmel_CG10498)

CG10498 gene product from transcript CG10498-RC

(Aliases: CDK2/CDC2c,DmCdk2,Dcdc2c,S(Sev-CycE)3A,Cdc2c,dCdk2,CDC2C,Dmel\CG10498,CG10498,Cdk2,CDK2,Dmcdc2c,DmCdc2,cdk2,CDC2c)

cdc2c biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
phosphorylation GO:0016310 294 0.921
Human Yeast Mouse Rat Fly
meiotic nuclear division GO:0007126 151 0.906
Yeast Fly
mitotic cell cycle phase transition GO:0044772 138 0.868
Mouse Fly
mitotic dna integrity checkpoint GO:0044774 75 0.844
Fly
nuclear division GO:0000280 332 0.840
Yeast Fly
organelle fission GO:0048285 340 0.814
Yeast Fly
mitotic dna damage checkpoint GO:0044773 74 0.753
Fly
negative regulation of cellular metabolic process GO:0031324 382 0.736
Yeast
dna integrity checkpoint GO:0031570 81 0.710
Fly
regulation of phosphate metabolic process GO:0019220 210 0.651
mitotic cell cycle checkpoint GO:0007093 88 0.642
Fly
intracellular signal transduction GO:0035556 300 0.593
aging GO:0007568 143 0.586
regulation of phosphorylation GO:0042325 147 0.582
mitotic g2 m transition checkpoint GO:0044818 70 0.553
Fly
mitotic g2 dna damage checkpoint GO:0007095 69 0.550
Fly
meiotic cell cycle process GO:1903046 132 0.512
Yeast
cell cycle checkpoint GO:0000075 95 0.493
Fly
negative regulation of mitotic cell cycle phase transition GO:1901991 103 0.482
Fly
protein modification process GO:0036211 438 0.474
Human Yeast Mouse Rat Fly
dna damage checkpoint GO:0000077 78 0.405
Fly
cell cycle dna replication GO:0044786 23 0.405
Yeast
eye development GO:0001654 323 0.402
Rat
negative regulation of cell cycle phase transition GO:1901988 103 0.373
Fly
regulation of phosphorus metabolic process GO:0051174 210 0.361
negative regulation of response to stimulus GO:0048585 258 0.333
Yeast
chromosome organization GO:0051276 360 0.318
Human Yeast
protein phosphorylation GO:0006468 169 0.315
Human Yeast Mouse Rat Fly
mitotic nuclear division GO:0007067 213 0.312
positive regulation of nitrogen compound metabolic process GO:0051173 354 0.309
Yeast Mouse
establishment of localization in cell GO:0051649 402 0.305
g2 dna damage checkpoint GO:0031572 69 0.305
Fly
meiotic chromosome segregation GO:0045132 59 0.305
developmental maturation GO:0021700 172 0.295
chromatin modification GO:0016568 147 0.294
Human Yeast
dna replication GO:0006260 48 0.284
Yeast Mouse
meiotic cell cycle GO:0051321 171 0.276
Yeast Fly
stem cell division GO:0017145 69 0.263
Fly
death GO:0016265 284 0.263
response to organic substance GO:0010033 284 0.256
Rat
regulation of protein metabolic process GO:0051246 256 0.243
regulation of cell cycle phase transition GO:1901987 130 0.242
Fly
cell cycle g1 s phase transition GO:0044843 31 0.231
Mouse Fly
regulation of mitotic cell cycle phase transition GO:1901990 130 0.222
Fly
response to organonitrogen compound GO:0010243 75 0.221
Rat
g1 s transition of mitotic cell cycle GO:0000082 31 0.218
Mouse Fly
apoptotic process GO:0006915 159 0.208
negative regulation of developmental process GO:0051093 201 0.208
negative regulation of cell cycle GO:0045786 116 0.195
Yeast Fly
regulation of programmed cell death GO:0043067 152 0.190
positive regulation of biosynthetic process GO:0009891 316 0.184
Yeast Mouse
cell proliferation GO:0008283 299 0.183
Human Fly
cell cycle phase transition GO:0044770 140 0.175
Mouse Fly
negative regulation of multicellular organismal process GO:0051241 142 0.175
regulation of developmental growth GO:0048638 174 0.174
organic substance catabolic process GO:1901575 308 0.173
Yeast
nuclear dna replication GO:0033260 1 0.172
Yeast
macromolecular complex assembly GO:0065003 256 0.169
protein catabolic process GO:0030163 101 0.168
developmental growth GO:0048589 280 0.163
cellular protein modification process GO:0006464 438 0.158
Human Yeast Mouse Rat Fly
macromolecule catabolic process GO:0009057 161 0.152
Yeast
regulation of cell cycle process GO:0010564 181 0.152
Yeast Fly
negative regulation of cellular macromolecule biosynthetic process GO:2000113 267 0.150
Yeast
programmed cell death GO:0012501 257 0.150
positive regulation of macromolecule metabolic process GO:0010604 405 0.148
Yeast Mouse
spindle organization GO:0007051 253 0.144
dna packaging GO:0006323 91 0.141
protein dna complex assembly GO:0065004 63 0.141
negative regulation of cell cycle g1 s phase transition GO:1902807 13 0.140
immune response GO:0006955 246 0.139
meiosis i GO:0007127 59 0.136
Yeast
regulation of cellular protein metabolic process GO:0032268 243 0.132
negative regulation of chromosome segregation GO:0051985 14 0.130
Yeast
circulatory system development GO:0072359 82 0.123
regulation of cell death GO:0010941 173 0.122
positive regulation of response to stimulus GO:0048584 323 0.122
regulation of mitotic cell cycle GO:0007346 190 0.116
Yeast Fly
ubiquitin dependent protein catabolic process GO:0006511 78 0.115
regulation of cell cycle GO:0051726 291 0.114
Human Yeast Mouse Rat Fly
single organism biosynthetic process GO:0044711 206 0.114
Yeast
endomitotic cell cycle GO:0007113 7 0.113
positive regulation of developmental process GO:0051094 143 0.109
regulation of dna replication GO:0006275 13 0.108
Yeast Mouse
protein complex assembly GO:0006461 200 0.108
cell death GO:0008219 279 0.108
multicellular organismal aging GO:0010259 140 0.107
negative regulation of meiotic cell cycle GO:0051447 2 0.106
Yeast
cellular catabolic process GO:0044248 372 0.106
Yeast
localization of cell GO:0051674 257 0.103
dna conformation change GO:0071103 105 0.102
secretion by cell GO:0032940 101 0.098
central nervous system development GO:0007417 201 0.097
positive regulation of nucleobase containing compound metabolic process GO:0045935 332 0.097
Yeast Mouse
regulation of apoptotic process GO:0042981 130 0.096
regulation of cell proliferation GO:0042127 163 0.095
Human
positive regulation of molecular function GO:0044093 136 0.095
signal transduction by phosphorylation GO:0023014 107 0.091
regulation of multicellular organismal development GO:2000026 414 0.089
modification dependent macromolecule catabolic process GO:0043632 79 0.089
negative regulation of biosynthetic process GO:0009890 277 0.089
Yeast
response to endogenous stimulus GO:0009719 119 0.086
Rat
proteolysis GO:0006508 192 0.086
response to nitrogen compound GO:1901698 90 0.085
Rat
regulation of protein kinase activity GO:0045859 51 0.084
muscle structure development GO:0061061 224 0.084
mapk cascade GO:0000165 107 0.081
positive regulation of protein metabolic process GO:0051247 128 0.081
muscle organ development GO:0007517 127 0.078
cell adhesion GO:0007155 136 0.077
imaginal disc derived appendage morphogenesis GO:0035114 395 0.076
chromosome segregation GO:0007059 157 0.076
Yeast
negative regulation of phosphate metabolic process GO:0045936 45 0.074
negative regulation of cell cycle process GO:0010948 109 0.072
Yeast Fly
negative regulation of mitotic cell cycle GO:0045930 109 0.072
Yeast Fly
regulation of intracellular signal transduction GO:1902531 236 0.071
negative regulation of phosphorus metabolic process GO:0010563 45 0.070
protein maturation GO:0051604 71 0.069
tissue migration GO:0090130 155 0.069
regulation of molecular function GO:0065009 217 0.069
cellular protein catabolic process GO:0044257 83 0.067
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 116 0.066
biological adhesion GO:0022610 138 0.065
protein transport GO:0015031 155 0.065
oocyte differentiation GO:0009994 145 0.064
organic substance transport GO:0071702 257 0.064
positive regulation of lipid catabolic process GO:0050996 1 0.063
Yeast
regulation of protein catabolic process GO:0042176 55 0.061
learning or memory GO:0007611 141 0.060
gliogenesis GO:0042063 80 0.060
cellular response to dna damage stimulus GO:0006974 223 0.059
Yeast Fly
modification dependent protein catabolic process GO:0019941 78 0.058
positive regulation of phosphorus metabolic process GO:0010562 139 0.058
telencephalon development GO:0021537 2 0.058
ameboidal type cell migration GO:0001667 151 0.058
positive regulation of programmed cell death GO:0043068 62 0.058
negative regulation of gene expression GO:0010629 387 0.057
Human Yeast
cardiovascular system development GO:0072358 82 0.057
negative regulation of g1 s transition of mitotic cell cycle GO:2000134 13 0.057
cell motility GO:0048870 251 0.057
positive regulation of phosphate metabolic process GO:0045937 139 0.056
positive regulation of signal transduction GO:0009967 223 0.055
male meiosis GO:0007140 52 0.054
Fly
negative regulation of transcription dna templated GO:0045892 237 0.054
Yeast
response to wounding GO:0009611 94 0.053
regulation of transferase activity GO:0051338 58 0.053
regulation of kinase activity GO:0043549 53 0.052
dna metabolic process GO:0006259 227 0.052
Yeast Mouse
regulation of nervous system development GO:0051960 248 0.052
histone modification GO:0016570 106 0.050
Human
protein complex biogenesis GO:0070271 201 0.050
protein localization GO:0008104 284 0.050
Yeast Fly
negative regulation of signaling GO:0023057 219 0.048
jak stat cascade GO:0007259 49 0.048
germarium derived egg chamber formation GO:0007293 101 0.048
Fly
mitotic cell cycle embryonic GO:0045448 38 0.048
intracellular protein transport GO:0006886 104 0.048
cellular macromolecular complex assembly GO:0034622 153 0.048
regulation of protein modification process GO:0031399 112 0.047
catabolic process GO:0009056 409 0.047
Yeast
positive regulation of phosphorylation GO:0042327 87 0.047
secretion GO:0046903 109 0.046
negative regulation of cell death GO:0060548 81 0.046
regulation of protein phosphorylation GO:0001932 64 0.046
cell migration GO:0016477 238 0.045
regulation of dna metabolic process GO:0051052 34 0.045
Yeast Mouse
body morphogenesis GO:0010171 2 0.045
dna dependent dna replication GO:0006261 17 0.045
Yeast Mouse
positive regulation of nucleic acid templated transcription GO:1903508 266 0.044
Yeast Mouse
columnar cuboidal epithelial cell development GO:0002066 249 0.044
positive regulation of signaling GO:0023056 243 0.044
regulation of cellular response to stress GO:0080135 89 0.044
Yeast
imaginal disc derived appendage development GO:0048737 399 0.044
proteolysis involved in cellular protein catabolic process GO:0051603 83 0.044
regulation of mapk cascade GO:0043408 92 0.044
syncytial blastoderm mitotic cell cycle GO:0035186 21 0.044
covalent chromatin modification GO:0016569 106 0.043
Human
somatic stem cell division GO:0048103 37 0.043
Fly
camera type eye development GO:0043010 4 0.043
Rat
negative regulation of programmed cell death GO:0043069 72 0.041
response to reactive oxygen species GO:0000302 24 0.040
response to oxygen containing compound GO:1901700 200 0.040
Rat
positive regulation of mitotic cell cycle GO:0045931 34 0.040
Yeast
ras protein signal transduction GO:0007265 88 0.039
Human
actin filament based process GO:0030029 220 0.039
regulation of cell differentiation GO:0045595 302 0.038
segmentation GO:0035282 207 0.038
regulation of cellular localization GO:0060341 136 0.037
negative regulation of cell communication GO:0010648 223 0.037
neural precursor cell proliferation GO:0061351 75 0.037
Fly
hindgut morphogenesis GO:0007442 58 0.037
eye morphogenesis GO:0048592 260 0.037
positive regulation of transcription dna templated GO:0045893 266 0.036
Yeast Mouse
mitotic sister chromatid segregation GO:0000070 87 0.036
negative regulation of cell differentiation GO:0045596 143 0.036
enzyme linked receptor protein signaling pathway GO:0007167 179 0.036
negative regulation of rna metabolic process GO:0051253 251 0.035
Yeast
negative regulation of erk1 and erk2 cascade GO:0070373 3 0.035
negative regulation of nucleobase containing compound metabolic process GO:0045934 261 0.034
Yeast
regulation of catalytic activity GO:0050790 185 0.033
rhythmic process GO:0048511 106 0.033
phosphorylation of rna polymerase ii c terminal domain GO:0070816 1 0.033
Yeast
cellular response to chemical stimulus GO:0070887 199 0.033
Rat
cellular response to hormone stimulus GO:0032870 44 0.033
Rat
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 54 0.033
regulation of multi organism process GO:0043900 131 0.033
single organism nuclear import GO:1902593 51 0.033
regulation of small gtpase mediated signal transduction GO:0051056 93 0.032
organelle assembly GO:0070925 198 0.032
posttranscriptional regulation of gene expression GO:0010608 145 0.032
positive regulation of developmental growth GO:0048639 62 0.032
brain development GO:0007420 120 0.031
positive regulation of cellular biosynthetic process GO:0031328 316 0.031
Yeast Mouse
negative regulation of apoptotic process GO:0043066 63 0.031
single organism intracellular transport GO:1902582 207 0.031
positive regulation of cell communication GO:0010647 250 0.031
epithelium migration GO:0090132 148 0.030
regulation of localization GO:0032879 275 0.030
Yeast Fly
female meiotic division GO:0007143 70 0.030
mrna processing GO:0006397 104 0.029
Yeast
regulation of transport GO:0051049 181 0.029
cell cycle comprising mitosis without cytokinesis GO:0033301 25 0.028
regulation of cell development GO:0060284 215 0.028
regulation of proteolysis GO:0030162 87 0.028
dna replication initiation GO:0006270 6 0.028
Mouse
regulation of response to stress GO:0080134 200 0.027
Yeast
regulation of erk1 and erk2 cascade GO:0070372 39 0.027
columnar cuboidal epithelial cell differentiation GO:0002065 256 0.027
determination of adult lifespan GO:0008340 137 0.026
regulation of cellular component biogenesis GO:0044087 201 0.026
negative regulation of intracellular signal transduction GO:1902532 57 0.026
chromatin organization GO:0006325 207 0.026
Human Yeast
sister chromatid cohesion GO:0007062 18 0.025
Yeast
regulation of immune system process GO:0002682 176 0.025
transcription from rna polymerase ii promoter GO:0006366 368 0.025
Yeast
dna recombination GO:0006310 32 0.025
Yeast
regulation of anatomical structure size GO:0090066 163 0.025
establishment or maintenance of cell polarity GO:0007163 167 0.025
sex differentiation GO:0007548 81 0.024
small gtpase mediated signal transduction GO:0007264 88 0.024
Human
regeneration GO:0031099 16 0.024
Rat
negative regulation of phosphorylation GO:0042326 35 0.024
positive regulation of cell cycle GO:0045787 43 0.023
Yeast
proteasomal protein catabolic process GO:0010498 59 0.023
compound eye development GO:0048749 307 0.023
camera type eye morphogenesis GO:0048593 2 0.023
regulation of dna recombination GO:0000018 4 0.023
Yeast
epithelial cell differentiation GO:0030855 322 0.022
dna endoreduplication GO:0042023 22 0.022
protein heterooligomerization GO:0051291 4 0.021
regulation of growth GO:0040008 233 0.021
Yeast
regulation of mrna metabolic process GO:1903311 72 0.021
negative regulation of signal transduction GO:0009968 206 0.021
negative regulation of chromosome organization GO:2001251 19 0.021
Yeast
neuroblast proliferation GO:0007405 74 0.021
Fly
post embryonic appendage morphogenesis GO:0035120 385 0.021
regulation of mitotic metaphase anaphase transition GO:0030071 26 0.021
cognition GO:0050890 141 0.020
striated muscle tissue development GO:0014706 27 0.020
positive regulation of gene expression GO:0010628 290 0.020
Yeast Mouse
epithelial cell migration GO:0010631 148 0.019
regulation of neural precursor cell proliferation GO:2000177 35 0.019
chromosome condensation GO:0030261 41 0.019
appendage development GO:0048736 401 0.018
regulation of metaphase anaphase transition of cell cycle GO:1902099 26 0.018
antimicrobial humoral response GO:0019730 99 0.018
cellular protein localization GO:0034613 160 0.018
ribonucleoprotein complex subunit organization GO:0071826 28 0.018
retina development in camera type eye GO:0060041 4 0.018
regulation of catabolic process GO:0009894 170 0.017
Yeast
mitotic spindle organization GO:0007052 220 0.017
establishment of protein localization GO:0045184 163 0.017
regulation of ras protein signal transduction GO:0046578 93 0.017
negative regulation of cellular biosynthetic process GO:0031327 277 0.017
Yeast
negative regulation of mitotic sister chromatid separation GO:2000816 13 0.017
positive regulation of growth GO:0045927 75 0.017
cellular macromolecule catabolic process GO:0044265 136 0.016
Yeast
erk1 and erk2 cascade GO:0070371 39 0.016
appendage morphogenesis GO:0035107 397 0.016
response to alkaloid GO:0043279 26 0.016
protein dna complex subunit organization GO:0071824 86 0.016
response to light stimulus GO:0009416 124 0.016
negative regulation of developmental growth GO:0048640 64 0.015
rna splicing via transesterification reactions with bulged adenosine as nucleophile GO:0000377 73 0.015
positive regulation of cell death GO:0010942 69 0.015
mitotic sister chromatid separation GO:0051306 30 0.015
cell maturation GO:0048469 144 0.015
compound eye morphogenesis GO:0001745 249 0.015
sister chromatid segregation GO:0000819 92 0.014
humoral immune response GO:0006959 117 0.014
response to peptide hormone GO:0043434 29 0.014
Rat
organonitrogen compound metabolic process GO:1901564 318 0.014
asymmetric cell division GO:0008356 37 0.014
Fly
regulation of immune response GO:0050776 118 0.014
gland development GO:0048732 191 0.014
digestive tract development GO:0048565 149 0.014
circulatory system process GO:0003013 37 0.014
cell type specific apoptotic process GO:0097285 38 0.014
metaphase anaphase transition of cell cycle GO:0044784 28 0.014
regulation of proteasomal protein catabolic process GO:0061136 39 0.013
mitotic spindle checkpoint GO:0071174 11 0.013
protein modification by small protein conjugation or removal GO:0070647 106 0.013
nitrogen compound transport GO:0071705 85 0.013
peptidyl threonine modification GO:0018210 3 0.013
regulation of neurogenesis GO:0050767 158 0.013
tissue morphogenesis GO:0048729 297 0.013
response to insulin GO:0032868 29 0.013
Rat
peptidyl threonine phosphorylation GO:0018107 2 0.013
negative regulation of mapk cascade GO:0043409 23 0.013
chitin based larval cuticle pattern formation GO:0035293 11 0.012
positive regulation of apoptotic process GO:0043065 47 0.012
reciprocal dna recombination GO:0035825 19 0.012
phagocytosis GO:0006909 215 0.012
wing disc morphogenesis GO:0007472 344 0.012
positive regulation of intracellular signal transduction GO:1902533 116 0.012
negative regulation of protein metabolic process GO:0051248 85 0.012
negative regulation of dna metabolic process GO:0051053 12 0.012
Yeast
homeostatic process GO:0042592 199 0.012
response to toxic substance GO:0009636 22 0.012
Rat
regulation of mitotic sister chromatid separation GO:0010965 28 0.012
imaginal disc derived wing morphogenesis GO:0007476 337 0.012
protein processing GO:0016485 68 0.011
peripheral nervous system development GO:0007422 52 0.011
positive regulation of cellular protein metabolic process GO:0032270 118 0.011
blastoderm segmentation GO:0007350 159 0.011
mitochondrial membrane organization GO:0007006 3 0.011
response to temperature stimulus GO:0009266 106 0.011
reproductive structure development GO:0048608 74 0.011
positive regulation of protein phosphorylation GO:0001934 34 0.011
positive regulation of protein kinase activity GO:0045860 25 0.011
embryonic pattern specification GO:0009880 174 0.011
protein targeting to nucleus GO:0044744 51 0.011
positive regulation of catalytic activity GO:0043085 118 0.011
response to decreased oxygen levels GO:0036293 58 0.011
regulation of cell cycle g1 s phase transition GO:1902806 23 0.011
neuroblast division GO:0055057 35 0.010
Fly
cellular response to nitrogen compound GO:1901699 51 0.010
Rat
regulation of cell division GO:0051302 72 0.010
Yeast
regulation of sister chromatid cohesion GO:0007063 2 0.010
Yeast
positive regulation of macromolecule biosynthetic process GO:0010557 283 0.010
Yeast Mouse
negative regulation of protein processing GO:0010955 31 0.010
chromosome separation GO:0051304 42 0.010

cdc2c disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

Disease DO term ID Size Probability Func Analog Org
cancer DOID:162 0 0.031
disease of cellular proliferation DOID:14566 0 0.031