Drosophila melanogaster

80 known processes

Deaf1 (Dmel_CG8567)

Deformed epidermal autoregulatory factor-1

(Aliases: DEAF-1,CG8567,Dmel\CG8567,DEAF1,Deaf-1,deaf1)

Deaf1 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
cellular amino acid metabolic process GO:0006520 61 0.352
peptidyl lysine modification GO:0018205 57 0.292
chromatin organization GO:0006325 207 0.214
appendage morphogenesis GO:0035107 397 0.209
imaginal disc derived appendage morphogenesis GO:0035114 395 0.200
post embryonic appendage morphogenesis GO:0035120 385 0.188
appendage development GO:0048736 401 0.178
organic acid metabolic process GO:0006082 103 0.154
positive regulation of nitrogen compound metabolic process GO:0051173 354 0.135
protein acetylation GO:0006473 39 0.130
stem cell development GO:0048864 79 0.125
single organism behavior GO:0044708 391 0.122
Mouse
imaginal disc derived wing morphogenesis GO:0007476 337 0.115
transcription from rna polymerase ii promoter GO:0006366 368 0.113
chromosome organization GO:0051276 360 0.111
cellular protein modification process GO:0006464 438 0.109
positive regulation of rna metabolic process GO:0051254 271 0.107
chromatin modification GO:0016568 147 0.105
programmed cell death GO:0012501 257 0.102
positive regulation of gene expression GO:0010628 290 0.099
rhythmic process GO:0048511 106 0.093
internal protein amino acid acetylation GO:0006475 38 0.087
oxoacid metabolic process GO:0043436 103 0.087
protein modification process GO:0036211 438 0.086
cell adhesion GO:0007155 136 0.083
carboxylic acid metabolic process GO:0019752 92 0.079
regulation of multicellular organismal development GO:2000026 414 0.079
Human Mouse
regulation of cellular amino acid metabolic process GO:0006521 0 0.076
regulation of mrna metabolic process GO:1903311 72 0.074
regulation of immune system process GO:0002682 176 0.074
small molecule metabolic process GO:0044281 305 0.070
positive regulation of macromolecule metabolic process GO:0010604 405 0.070
amine metabolic process GO:0009308 12 0.067
regulation of cellular ketone metabolic process GO:0010565 3 0.065
wing disc morphogenesis GO:0007472 344 0.065
intracellular signal transduction GO:0035556 300 0.063
anterior posterior pattern specification GO:0009952 136 0.062
cellular amine metabolic process GO:0044106 12 0.062
regulation of cell death GO:0010941 173 0.061
enzyme linked receptor protein signaling pathway GO:0007167 179 0.060
histone modification GO:0016570 106 0.059
cognition GO:0050890 141 0.056
Mouse
covalent chromatin modification GO:0016569 106 0.055
long term memory GO:0007616 62 0.054
regulation of cellular amine metabolic process GO:0033238 3 0.054
cellular ketone metabolic process GO:0042180 24 0.054
regulation of apoptotic process GO:0042981 130 0.053
columnar cuboidal epithelial cell differentiation GO:0002065 256 0.052
small gtpase mediated signal transduction GO:0007264 88 0.052
cell death GO:0008219 279 0.051
regulation of programmed cell death GO:0043067 152 0.050
imaginal disc derived appendage development GO:0048737 399 0.050
negative regulation of nucleobase containing compound metabolic process GO:0045934 261 0.048
Human
microtubule based movement GO:0007018 51 0.048
peptidyl amino acid modification GO:0018193 105 0.047
central nervous system development GO:0007417 201 0.047
exocrine system development GO:0035272 162 0.046
regulation of organ morphogenesis GO:2000027 78 0.044
positive regulation of rna biosynthetic process GO:1902680 266 0.044
regulation of cell differentiation GO:0045595 302 0.043
r7 cell differentiation GO:0045466 43 0.043
cellular response to chemical stimulus GO:0070887 199 0.043
positive regulation of nucleic acid templated transcription GO:1903508 266 0.042
compound eye morphogenesis GO:0001745 249 0.042
jak stat cascade GO:0007259 49 0.042
anterior posterior axis specification embryo GO:0008595 103 0.041
regulation of protein acetylation GO:1901983 7 0.041
regulation of localization GO:0032879 275 0.040
muscle organ development GO:0007517 127 0.040
positive regulation of transcription dna templated GO:0045893 266 0.040
catabolic process GO:0009056 409 0.040
cell maturation GO:0048469 144 0.039
intrinsic apoptotic signaling pathway GO:0097193 16 0.039
columnar cuboidal epithelial cell development GO:0002066 249 0.039
biological adhesion GO:0022610 138 0.038
negative regulation of cellular macromolecule biosynthetic process GO:2000113 267 0.038
Human
negative regulation of gene expression GO:0010629 387 0.038
Human
cell proliferation GO:0008283 299 0.037
Human Mouse
circadian behavior GO:0048512 76 0.037
negative regulation of neurogenesis GO:0050768 53 0.037
negative regulation of cell differentiation GO:0045596 143 0.037
regulation of transcription from rna polymerase ii promoter GO:0006357 378 0.036
negative regulation of gene expression epigenetic GO:0045814 77 0.036
peptidyl lysine acetylation GO:0018394 39 0.036
protein complex biogenesis GO:0070271 201 0.035
response to hypoxia GO:0001666 53 0.035
photoreceptor cell development GO:0042461 96 0.035
organonitrogen compound metabolic process GO:1901564 318 0.034
response to anesthetic GO:0072347 9 0.034
positive regulation of response to stimulus GO:0048584 323 0.034
positive regulation of signal transduction GO:0009967 223 0.034
histone acetylation GO:0016573 38 0.033
learning or memory GO:0007611 141 0.033
Mouse
dendrite development GO:0016358 204 0.031
positive regulation of biosynthetic process GO:0009891 316 0.031
protein modification by small protein conjugation or removal GO:0070647 106 0.030
protein phosphorylation GO:0006468 169 0.030
proteolysis GO:0006508 192 0.029
defense response to bacterium GO:0042742 178 0.029
positive regulation of cell communication GO:0010647 250 0.029
apoptotic process GO:0006915 159 0.029
stem cell maintenance GO:0019827 67 0.029
regulation of immune response GO:0050776 118 0.028
positive regulation of cellular biosynthetic process GO:0031328 316 0.028
positive regulation of cellular component organization GO:0051130 156 0.028
response to abiotic stimulus GO:0009628 341 0.028
Mouse
regulation of cell proliferation GO:0042127 163 0.027
Human Mouse
negative regulation of response to stimulus GO:0048585 258 0.027
response to endogenous stimulus GO:0009719 119 0.027
positive regulation of cell death GO:0010942 69 0.027
sensory organ morphogenesis GO:0090596 260 0.026
positive regulation of signaling GO:0023056 243 0.026
negative regulation of cellular metabolic process GO:0031324 382 0.026
Human
regulation of mrna splicing via spliceosome GO:0048024 64 0.026
alternative mrna splicing via spliceosome GO:0000380 60 0.026
regulation of circadian rhythm GO:0042752 49 0.026
immune system process GO:0002376 347 0.026
gland morphogenesis GO:0022612 145 0.025
negative regulation of signaling GO:0023057 219 0.025
organic cyclic compound catabolic process GO:1901361 168 0.025
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 116 0.025
memory GO:0007613 94 0.024
sister chromatid segregation GO:0000819 92 0.024
inter male aggressive behavior GO:0002121 60 0.024
salivary gland development GO:0007431 162 0.024
regulation of cellular protein metabolic process GO:0032268 243 0.024
molting cycle chitin based cuticle GO:0007591 56 0.024
response to organic cyclic compound GO:0014070 89 0.024
regulation of histone deacetylation GO:0031063 2 0.024
response to external biotic stimulus GO:0043207 293 0.024
defense response to fungus GO:0050832 48 0.023
glutamine metabolic process GO:0006541 4 0.023
response to decreased oxygen levels GO:0036293 58 0.023
regulation of embryonic development GO:0045995 68 0.023
regulation of gene expression epigenetic GO:0040029 128 0.023
production of molecular mediator of immune response GO:0002440 46 0.023
positive regulation of nucleobase containing compound metabolic process GO:0045935 332 0.023
macromolecule catabolic process GO:0009057 161 0.023
mrna splicing via spliceosome GO:0000398 73 0.022
compound eye development GO:0048749 307 0.022
negative regulation of nervous system development GO:0051961 92 0.022
response to extracellular stimulus GO:0009991 116 0.022
hematopoietic progenitor cell differentiation GO:0002244 1 0.022
spermatogenesis GO:0007283 200 0.022
regulation of defense response GO:0031347 102 0.022
death GO:0016265 284 0.022
carbohydrate biosynthetic process GO:0016051 17 0.022
meiotic chromosome segregation GO:0045132 59 0.021
phagocytosis GO:0006909 215 0.021
mitotic nuclear division GO:0007067 213 0.021
organic substance catabolic process GO:1901575 308 0.021
somatic muscle development GO:0007525 66 0.021
macromolecule deacylation GO:0098732 11 0.021
developmental programmed cell death GO:0010623 138 0.021
regulation of protein modification process GO:0031399 112 0.021
cellular response to decreased oxygen levels GO:0036294 30 0.021
organic substance transport GO:0071702 257 0.020
negative regulation of developmental process GO:0051093 201 0.020
eye photoreceptor cell differentiation GO:0001754 145 0.020
imaginal disc derived wing vein morphogenesis GO:0008586 44 0.020
cellular response to organic substance GO:0071310 132 0.020
cellular response to oxygen levels GO:0071453 30 0.019
ras protein signal transduction GO:0007265 88 0.019
epithelial cell differentiation GO:0030855 322 0.019
hindbrain development GO:0030902 2 0.019
cell cell junction organization GO:0045216 55 0.019
single organism cell adhesion GO:0098602 47 0.019
digestive system development GO:0055123 149 0.018
regulation of nervous system development GO:0051960 248 0.018
regulation of gene silencing GO:0060968 63 0.018
positive regulation of cellular amine metabolic process GO:0033240 0 0.018
cell cycle comprising mitosis without cytokinesis GO:0033301 25 0.018
secretion by cell GO:0032940 101 0.018
single organismal cell cell adhesion GO:0016337 45 0.018
regulation of anatomical structure morphogenesis GO:0022603 242 0.018
cellular macromolecule catabolic process GO:0044265 136 0.018
regulation of innate immune response GO:0045088 71 0.018
regulation of membrane potential GO:0042391 35 0.018
embryonic axis specification GO:0000578 107 0.017
immune response GO:0006955 246 0.017
negative regulation of signal transduction GO:0009968 206 0.017
circadian rhythm GO:0007623 105 0.017
internal peptidyl lysine acetylation GO:0018393 38 0.017
cell projection assembly GO:0030031 94 0.016
positive regulation of cellular amino acid metabolic process GO:0045764 0 0.016
regulation of protein metabolic process GO:0051246 256 0.016
photoreceptor cell fate commitment GO:0046552 41 0.016
positive regulation of programmed cell death GO:0043068 62 0.016
cell surface receptor signaling pathway involved in heart development GO:0061311 3 0.016
protein acylation GO:0043543 42 0.016
eye photoreceptor cell fate commitment GO:0042706 37 0.016
protein modification by small protein conjugation GO:0032446 79 0.016
tissue death GO:0016271 102 0.016
response to organic substance GO:0010033 284 0.016
stem cell differentiation GO:0048863 117 0.016
positive regulation of stem cell differentiation GO:2000738 3 0.016
imaginal disc pattern formation GO:0007447 91 0.015
positive regulation of catalytic activity GO:0043085 118 0.015
regulation of peptidase activity GO:0052547 39 0.015
macromolecule methylation GO:0043414 45 0.015
regulation of apoptotic signaling pathway GO:2001233 10 0.015
positive regulation of transcription from rna polymerase ii promoter GO:0045944 204 0.015
tripartite regional subdivision GO:0007351 103 0.015
negative regulation of protein metabolic process GO:0051248 85 0.015
cellular protein complex assembly GO:0043623 71 0.015
endocytosis GO:0006897 310 0.015
salivary gland cell autophagic cell death GO:0035071 83 0.015
gene silencing GO:0016458 138 0.015
regulation of alternative mrna splicing via spliceosome GO:0000381 60 0.015
cellular response to hypoxia GO:0071456 28 0.015
phosphorylation GO:0016310 294 0.014
anterior posterior axis specification GO:0009948 109 0.014
regulation of intracellular signal transduction GO:1902531 236 0.014
adult behavior GO:0030534 137 0.014
photoreceptor cell differentiation GO:0046530 170 0.014
microtubule based transport GO:0010970 42 0.014
convergent extension GO:0060026 2 0.014
stem cell division GO:0017145 69 0.014
axonogenesis GO:0007409 290 0.014
histone deacetylation GO:0016575 9 0.014
neuron apoptotic process GO:0051402 17 0.014
organelle fission GO:0048285 340 0.014
response to other organism GO:0051707 293 0.014
cellular response to external stimulus GO:0071496 66 0.014
positive regulation of cellular catabolic process GO:0031331 95 0.014
cellular response to sterol depletion GO:0071501 3 0.014
negative regulation of cell cell adhesion GO:0022408 8 0.014
macromolecular complex assembly GO:0065003 256 0.014
pole plasm mrna localization GO:0019094 49 0.013
regulation of epithelial cell differentiation GO:0030856 4 0.013
apoptotic process involved in development GO:1902742 20 0.013
body morphogenesis GO:0010171 2 0.013
actin cytoskeleton organization GO:0030036 206 0.013
ovarian follicle cell development GO:0030707 248 0.013
neurological system process GO:0050877 358 0.013
Mouse
developmental maturation GO:0021700 172 0.013
cellular macromolecule localization GO:0070727 220 0.013
chaeta development GO:0022416 97 0.013
mating GO:0007618 120 0.013
multi organism reproductive behavior GO:0044705 121 0.013
aromatic compound catabolic process GO:0019439 166 0.013
humoral immune response GO:0006959 117 0.013
positive regulation of immune system process GO:0002684 68 0.013
regulation of phosphorylation GO:0042325 147 0.013
epithelial cell development GO:0002064 274 0.013
negative regulation of smoothened signaling pathway GO:0045879 16 0.013
mitochondrion organization GO:0007005 65 0.013
insulin like growth factor receptor signaling pathway GO:0048009 5 0.013
salivary gland morphogenesis GO:0007435 145 0.013
actin polymerization or depolymerization GO:0008154 31 0.013
regulation of mrna processing GO:0050684 71 0.013
signal transduction in response to dna damage GO:0042770 3 0.013
negative regulation of cell death GO:0060548 81 0.012
rhythmic behavior GO:0007622 76 0.012
forebrain development GO:0030900 2 0.012
tracheal outgrowth open tracheal system GO:0007426 18 0.012
positive regulation of histone deacetylation GO:0031065 2 0.012
carbohydrate metabolic process GO:0005975 82 0.012
ovarian follicle cell migration GO:0007297 121 0.012
histone h4 acetylation GO:0043967 13 0.012
regulation of ras protein signal transduction GO:0046578 93 0.012
protein ubiquitination GO:0016567 70 0.012
cellular response to dna damage stimulus GO:0006974 223 0.012
cell motility GO:0048870 251 0.012
muscle structure development GO:0061061 224 0.012
imaginal disc derived wing vein specification GO:0007474 48 0.012
negative regulation of cellular protein metabolic process GO:0032269 85 0.012
positive regulation of apoptotic signaling pathway GO:2001235 4 0.011
cell cycle phase transition GO:0044770 140 0.011
locomotory behavior GO:0007626 176 0.011
germ line stem cell division GO:0042078 25 0.011
taxis GO:0042330 304 0.011
actin filament based process GO:0030029 220 0.011
regulation of histone h3 k9 methylation GO:0051570 3 0.011
response to oxygen containing compound GO:1901700 200 0.011
imaginal disc derived leg morphogenesis GO:0007480 80 0.011
response to alkaloid GO:0043279 26 0.011
camera type eye development GO:0043010 4 0.011
establishment of localization in cell GO:0051649 402 0.011
wing disc pattern formation GO:0035222 66 0.011
digestive tract development GO:0048565 149 0.011
regulation of cell projection organization GO:0031344 92 0.011
regulation of response to external stimulus GO:0032101 115 0.011
skeletal muscle adaptation GO:0043501 1 0.011
rna splicing GO:0008380 83 0.011
positive regulation of immune response GO:0050778 63 0.010
circadian regulation of gene expression GO:0032922 5 0.010
spliceosomal complex assembly GO:0000245 1 0.010
cellular component assembly involved in morphogenesis GO:0010927 151 0.010
response to ecdysone GO:0035075 34 0.010
regulation of purine nucleotide metabolic process GO:1900542 62 0.010
dosage compensation GO:0007549 16 0.010
developmental growth involved in morphogenesis GO:0060560 65 0.010
regulation of translation GO:0006417 56 0.010
morphogenesis of follicular epithelium GO:0016333 36 0.010
regulation of small gtpase mediated signal transduction GO:0051056 93 0.010
immune system development GO:0002520 57 0.010
translation GO:0006412 69 0.010

Deaf1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.048
musculoskeletal system disease DOID:17 0 0.020
nervous system disease DOID:863 0 0.019