Drosophila melanogaster

0 known processes

Cyp4e2 (Dmel_CG2060)

Cytochrome P450-4e2

(Aliases: P-450,Cyt-P450-4E2,CG2060,Dmel\CG2060,4e2,P450,CYP4E2)

Cyp4e2 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
xenobiotic catabolic process GO:0042178 1 0.764
insecticide metabolic process GO:0017143 2 0.445
polyol biosynthetic process GO:0046173 3 0.339
medium chain fatty acid metabolic process GO:0051791 1 0.298
steroid catabolic process GO:0006706 1 0.287
lipid catabolic process GO:0016042 21 0.273
response to xenobiotic stimulus GO:0009410 5 0.251
cellular ketone metabolic process GO:0042180 24 0.237
fat soluble vitamin metabolic process GO:0006775 1 0.236
fatty acid metabolic process GO:0006631 20 0.227
cellular lipid metabolic process GO:0044255 83 0.207
steroid biosynthetic process GO:0006694 16 0.207
response to organic substance GO:0010033 284 0.199
vitamin metabolic process GO:0006766 2 0.185
secondary metabolite catabolic process GO:0090487 1 0.156
response to toxic substance GO:0009636 22 0.154
response to mercury ion GO:0046689 3 0.133
cellular hormone metabolic process GO:0034754 23 0.128
small molecule metabolic process GO:0044281 305 0.124
fat soluble vitamin biosynthetic process GO:0042362 1 0.124
organic hydroxy compound biosynthetic process GO:1901617 21 0.114
insecticide catabolic process GO:0046701 1 0.112
steroid metabolic process GO:0008202 20 0.108
ketone biosynthetic process GO:0042181 16 0.106
toxin metabolic process GO:0009404 2 0.106
developmental growth GO:0048589 280 0.095
oxoacid metabolic process GO:0043436 103 0.091
secondary metabolic process GO:0019748 75 0.089
hormone catabolic process GO:0042447 3 0.085
single organism catabolic process GO:0044712 228 0.083
regulation of growth GO:0040008 233 0.082
cellular chemical homeostasis GO:0055082 40 0.082
organic acid metabolic process GO:0006082 103 0.081
lipid biosynthetic process GO:0008610 46 0.081
acetaldehyde metabolic process GO:0006117 5 0.080
vitamin biosynthetic process GO:0009110 1 0.080
response to abiotic stimulus GO:0009628 341 0.079
aggressive behavior GO:0002118 63 0.079
regulation of hormone levels GO:0010817 40 0.078
response to organic cyclic compound GO:0014070 89 0.077
sensory perception of smell GO:0007608 80 0.076
monocarboxylic acid metabolic process GO:0032787 29 0.070
growth GO:0040007 359 0.066
thioester metabolic process GO:0035383 3 0.065
neurological system process GO:0050877 358 0.065
chemical homeostasis GO:0048878 92 0.065
toxin catabolic process GO:0009407 1 0.064
lipid metabolic process GO:0006629 121 0.061
ion homeostasis GO:0050801 55 0.060
cellular catabolic process GO:0044248 372 0.058
response to inorganic substance GO:0010035 44 0.058
response to caffeine GO:0031000 12 0.057
anion homeostasis GO:0055081 3 0.057
terpenoid metabolic process GO:0006721 7 0.057
negative regulation of gene expression GO:0010629 387 0.056
cellular ion homeostasis GO:0006873 39 0.056
sensory perception of chemical stimulus GO:0007606 116 0.055
positive regulation of multicellular organismal process GO:0051240 143 0.055
cellular nitrogen compound catabolic process GO:0044270 165 0.054
carbohydrate biosynthetic process GO:0016051 17 0.054
single organism biosynthetic process GO:0044711 206 0.053
response to nitrogen compound GO:1901698 90 0.053
regulation of developmental growth GO:0048638 174 0.053
lauric acid metabolic process GO:0048252 1 0.053
organic hydroxy compound metabolic process GO:1901615 83 0.053
sterol metabolic process GO:0016125 12 0.053
small molecule biosynthetic process GO:0044283 37 0.051
response to temperature stimulus GO:0009266 106 0.051
catabolic process GO:0009056 409 0.051
organonitrogen compound metabolic process GO:1901564 318 0.050
hormone metabolic process GO:0042445 33 0.050
organic substance catabolic process GO:1901575 308 0.050
regulation of cellular ketone metabolic process GO:0010565 3 0.050
isoprenoid metabolic process GO:0006720 8 0.049
regulation of multicellular organismal development GO:2000026 414 0.049
response to nutrient levels GO:0031667 114 0.048
response to lipopolysaccharide GO:0032496 4 0.047
ecdysteroid biosynthetic process GO:0045456 15 0.046
carboxylic acid metabolic process GO:0019752 92 0.046
transcription from rna polymerase ii promoter GO:0006366 368 0.046
positive regulation of cell communication GO:0010647 250 0.046
sulfur compound metabolic process GO:0006790 59 0.044
oxidation reduction process GO:0055114 123 0.044
homeostatic process GO:0042592 199 0.044
defense response to gram negative bacterium GO:0050829 94 0.043
response to bacterium GO:0009617 198 0.042
cellular homeostasis GO:0019725 80 0.042
single organism behavior GO:0044708 391 0.041
negative regulation of biosynthetic process GO:0009890 277 0.039
positive regulation of macromolecule metabolic process GO:0010604 405 0.039
alcohol biosynthetic process GO:0046165 14 0.039
peptide metabolic process GO:0006518 80 0.038
positive regulation of lipid metabolic process GO:0045834 4 0.038
androgen metabolic process GO:0008209 1 0.037
response to oxygen containing compound GO:1901700 200 0.036
positive regulation of signal transduction GO:0009967 223 0.036
organic cyclic compound catabolic process GO:1901361 168 0.035
multi organism behavior GO:0051705 175 0.035
glutathione metabolic process GO:0006749 37 0.035
positive regulation of biosynthetic process GO:0009891 316 0.035
response to organonitrogen compound GO:0010243 75 0.033
negative regulation of cellular macromolecule biosynthetic process GO:2000113 267 0.033
mrna metabolic process GO:0016071 124 0.033
cellular lipid catabolic process GO:0044242 16 0.033
rna processing GO:0006396 147 0.033
response to alkaloid GO:0043279 26 0.032
lateral inhibition GO:0046331 206 0.032
regulation of anatomical structure size GO:0090066 163 0.032
ecdysteroid metabolic process GO:0045455 19 0.031
tube morphogenesis GO:0035239 191 0.031
digestive tract development GO:0048565 149 0.030
regulation of cell death GO:0010941 173 0.030
sterol biosynthetic process GO:0016126 9 0.029
estrogen metabolic process GO:0008210 1 0.029
negative regulation of cellular metabolic process GO:0031324 382 0.029
negative regulation of cellular biosynthetic process GO:0031327 277 0.028
alcohol metabolic process GO:0006066 25 0.028
ecdysone metabolic process GO:0008205 11 0.028
positive regulation of gene expression GO:0010628 290 0.028
ecdysone biosynthetic process GO:0006697 9 0.026
body morphogenesis GO:0010171 2 0.026
response to drug GO:0042493 17 0.026
respiratory system development GO:0060541 213 0.026
positive regulation of response to stimulus GO:0048584 323 0.026
cellular protein modification process GO:0006464 438 0.026
death GO:0016265 284 0.025
regionalization GO:0003002 416 0.025
cellular response to chemical stimulus GO:0070887 199 0.025
response to other organism GO:0051707 293 0.025
rna splicing via transesterification reactions with bulged adenosine as nucleophile GO:0000377 73 0.024
response to endogenous stimulus GO:0009719 119 0.023
cellular response to oxygen containing compound GO:1901701 79 0.023
sesquiterpenoid metabolic process GO:0006714 3 0.023
negative regulation of rna metabolic process GO:0051253 251 0.023
appendage development GO:0048736 401 0.022
positive regulation of signaling GO:0023056 243 0.022
defense response to bacterium GO:0042742 178 0.022
mrna splicing via spliceosome GO:0000398 73 0.022
response to biotic stimulus GO:0009607 294 0.022
response to insecticide GO:0017085 14 0.022
response to organophosphorus GO:0046683 2 0.022
inter male aggressive behavior GO:0002121 60 0.021
peptidyl lysine modification GO:0018205 57 0.021
negative regulation of nucleic acid templated transcription GO:1903507 240 0.021
appendage morphogenesis GO:0035107 397 0.021
proteolysis GO:0006508 192 0.021
regulation of cell cycle GO:0051726 291 0.021
single organism carbohydrate metabolic process GO:0044723 72 0.021
juvenile hormone metabolic process GO:0006716 3 0.021
telencephalon development GO:0021537 2 0.021
negative regulation of transcription dna templated GO:0045892 237 0.021
spindle organization GO:0007051 253 0.020
cell proliferation GO:0008283 299 0.020
negative regulation of macromolecule biosynthetic process GO:0010558 270 0.020
embryonic morphogenesis GO:0048598 206 0.020
hormone biosynthetic process GO:0042446 20 0.020
intracellular signal transduction GO:0035556 300 0.020
regulation of cell differentiation GO:0045595 302 0.020
ion transmembrane transport GO:0034220 122 0.020
regulation of programmed cell death GO:0043067 152 0.019
defense response to other organism GO:0098542 225 0.019
chromosome organization GO:0051276 360 0.019
organelle fission GO:0048285 340 0.019
wing disc morphogenesis GO:0007472 344 0.019
cell death GO:0008219 279 0.019
digestive system development GO:0055123 149 0.019
open tracheal system development GO:0007424 204 0.019
rna splicing via transesterification reactions GO:0000375 73 0.019
acyl coa metabolic process GO:0006637 3 0.019
negative regulation of transcription from rna polymerase ii promoter GO:0000122 119 0.019
response to external biotic stimulus GO:0043207 293 0.019
aging GO:0007568 143 0.019
purine ribonucleotide metabolic process GO:0009150 145 0.019
regulation of cell proliferation GO:0042127 163 0.018
imaginal disc derived wing morphogenesis GO:0007476 337 0.018
glycosyl compound metabolic process GO:1901657 127 0.018
positive regulation of cell motility GO:2000147 3 0.018
tube development GO:0035295 244 0.018
cell cell signaling involved in cell fate commitment GO:0045168 210 0.018
cellular amide metabolic process GO:0043603 80 0.018
aromatic compound catabolic process GO:0019439 166 0.018
negative regulation of rna biosynthetic process GO:1902679 240 0.018
negative regulation of nitrogen compound metabolic process GO:0051172 265 0.017
very long chain fatty acid metabolic process GO:0000038 4 0.017
organonitrogen compound catabolic process GO:1901565 128 0.017
response to alcohol GO:0097305 95 0.017
regulation of steroid metabolic process GO:0019218 2 0.017
establishment of localization in cell GO:0051649 402 0.017
positive regulation of rna metabolic process GO:0051254 271 0.017
epithelial cell differentiation GO:0030855 322 0.017
regulation of tube size GO:0035150 46 0.017
fatty acid beta oxidation GO:0006635 6 0.017
imaginal disc derived appendage development GO:0048737 399 0.017
regulation of gene expression epigenetic GO:0040029 128 0.017
regulation of localization GO:0032879 275 0.017
generation of precursor metabolites and energy GO:0006091 42 0.017
protein localization GO:0008104 284 0.016
positive regulation of nucleobase containing compound metabolic process GO:0045935 332 0.016
cell motility GO:0048870 251 0.016
defense response GO:0006952 300 0.016
regulation of molecular function GO:0065009 217 0.016
regulation of apoptotic process GO:0042981 130 0.016
kidney development GO:0001822 3 0.016
nucleoside phosphate metabolic process GO:0006753 162 0.016
response to glucose GO:0009749 2 0.016
peptidyl amino acid modification GO:0018193 105 0.016
carbohydrate metabolic process GO:0005975 82 0.015
forebrain development GO:0030900 2 0.015
cation homeostasis GO:0055080 51 0.015
regulation of transcription from rna polymerase ii promoter GO:0006357 378 0.015
connective tissue development GO:0061448 3 0.015
cholesterol homeostasis GO:0042632 3 0.015
post embryonic appendage morphogenesis GO:0035120 385 0.015
ameboidal type cell migration GO:0001667 151 0.015
sensory perception GO:0007600 196 0.015
lipid modification GO:0030258 24 0.015
regulation of transport GO:0051049 181 0.015
response to hexose GO:0009746 3 0.015
circulatory system process GO:0003013 37 0.015
neuron projection guidance GO:0097485 241 0.015
programmed cell death GO:0012501 257 0.015
glycerolipid catabolic process GO:0046503 3 0.014
imaginal disc derived appendage morphogenesis GO:0035114 395 0.014
response to extracellular stimulus GO:0009991 116 0.014
rna splicing GO:0008380 83 0.014
ion transport GO:0006811 145 0.014
protein acylation GO:0043543 42 0.014
response to ketone GO:1901654 34 0.014
acylglycerol biosynthetic process GO:0046463 2 0.014
single organism intracellular transport GO:1902582 207 0.014
camera type eye development GO:0043010 4 0.014
xenobiotic metabolic process GO:0006805 5 0.014
positive regulation of rna biosynthetic process GO:1902680 266 0.014
gene silencing GO:0016458 138 0.014
chitin based cuticle development GO:0040003 49 0.014
regulation of proteolysis GO:0030162 87 0.014
positive regulation of cell migration GO:0030335 2 0.014
tissue morphogenesis GO:0048729 297 0.014
nucleoside catabolic process GO:0009164 112 0.014
mrna processing GO:0006397 104 0.014
regulation of rna splicing GO:0043484 69 0.014
positive regulation of cellular biosynthetic process GO:0031328 316 0.013
regulation of cellular amine metabolic process GO:0033238 3 0.013
embryonic development via the syncytial blastoderm GO:0001700 148 0.013
protein modification process GO:0036211 438 0.013
immune system process GO:0002376 347 0.013
cellular response to xenobiotic stimulus GO:0071466 5 0.013
protein complex biogenesis GO:0070271 201 0.013
positive regulation of developmental process GO:0051094 143 0.013
nucleotide metabolic process GO:0009117 161 0.013
intracellular transport GO:0046907 228 0.013
negative regulation of nucleobase containing compound metabolic process GO:0045934 261 0.013
response to cadmium ion GO:0046686 9 0.013
negative regulation of cell death GO:0060548 81 0.012
chromatin modification GO:0016568 147 0.012
response to ethanol GO:0045471 59 0.012
endocytosis GO:0006897 310 0.012
sex differentiation GO:0007548 81 0.012
response to purine containing compound GO:0014074 12 0.012
neuron recognition GO:0008038 101 0.012
protein acetylation GO:0006473 39 0.012
positive regulation of catalytic activity GO:0043085 118 0.012
internal protein amino acid acetylation GO:0006475 38 0.012
nucleoside phosphate catabolic process GO:1901292 110 0.012
secretion GO:0046903 109 0.012
eye development GO:0001654 323 0.012
cellular amine metabolic process GO:0044106 12 0.012
regulation of nervous system development GO:0051960 248 0.012
amine metabolic process GO:0009308 12 0.012
cellular amino acid metabolic process GO:0006520 61 0.012
regulation of immune system process GO:0002682 176 0.012
acetylcholine catabolic process GO:0006581 1 0.012
nadh metabolic process GO:0006734 1 0.012
negative regulation of cellular protein metabolic process GO:0032269 85 0.012
digestive tract morphogenesis GO:0048546 127 0.012
heterocycle catabolic process GO:0046700 166 0.012
cellular response to hexose stimulus GO:0071331 1 0.011
ribonucleoside triphosphate catabolic process GO:0009203 108 0.011
dna metabolic process GO:0006259 227 0.011
cellular response to ethanol GO:0071361 4 0.011
organic substance transport GO:0071702 257 0.011
cuticle development GO:0042335 86 0.011
sterol homeostasis GO:0055092 4 0.011
head involution GO:0008258 35 0.011
purine nucleoside metabolic process GO:0042278 127 0.011
cellular response to dna damage stimulus GO:0006974 223 0.011
response to ddt GO:0046680 5 0.011
positive regulation of transcription dna templated GO:0045893 266 0.011
phagocytosis GO:0006909 215 0.011
epithelial cell development GO:0002064 274 0.011
retina development in camera type eye GO:0060041 4 0.011
mitotic spindle organization GO:0007052 220 0.011
response to starvation GO:0042594 97 0.011
purine nucleoside triphosphate metabolic process GO:0009144 119 0.011
axon guidance GO:0007411 233 0.011
gastrulation involving germ band extension GO:0010004 36 0.011
negative regulation of cell communication GO:0010648 223 0.011
positive regulation of nitrogen compound metabolic process GO:0051173 354 0.011
response to heat GO:0009408 63 0.011
cellular response to carbohydrate stimulus GO:0071322 4 0.011
gliogenesis GO:0042063 80 0.011
gland development GO:0048732 191 0.011
cellular macromolecular complex assembly GO:0034622 153 0.011
vesicle mediated transport GO:0016192 381 0.010
regulation of mrna splicing via spliceosome GO:0048024 64 0.010
carbohydrate derivative catabolic process GO:1901136 118 0.010
morphogenesis of an epithelium GO:0002009 276 0.010
thiosulfate transport GO:0015709 2 0.010
cell migration GO:0016477 238 0.010
carbohydrate derivative metabolic process GO:1901135 217 0.010
neutral lipid catabolic process GO:0046461 3 0.010
negative regulation of sequence specific dna binding transcription factor activity GO:0043433 4 0.010
regulation of cellular protein metabolic process GO:0032268 243 0.010
cellular biogenic amine catabolic process GO:0042402 1 0.010

Cyp4e2 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

Disease DO term ID Size Probability Func Analog Org
artery disease DOID:0050828 0 0.091
disease of anatomical entity DOID:7 0 0.091
vascular disease DOID:178 0 0.091
cardiovascular system disease DOID:1287 0 0.091
hypertension DOID:10763 0 0.065
essential hypertension DOID:10825 0 0.022
renal tubular transport disease DOID:447 0 0.013
kidney disease DOID:557 0 0.013
urinary system disease DOID:18 0 0.013
musculoskeletal system disease DOID:17 0 0.011
disease of metabolism DOID:0014667 0 0.011