|
|
negative regulation of nucleobase containing compound metabolic process
|
GO:0045934 |
261 |
0.143
|
|
|
|
negative regulation of nitrogen compound metabolic process
|
GO:0051172 |
265 |
0.137
|
|
|
|
negative regulation of gene expression
|
GO:0010629 |
387 |
0.122
|
|
|
|
negative regulation of macromolecule biosynthetic process
|
GO:0010558 |
270 |
0.119
|
|
|
|
regulation of cell differentiation
|
GO:0045595 |
302 |
0.115
|
Fly |
|
|
negative regulation of transcription dna templated
|
GO:0045892 |
237 |
0.103
|
|
|
|
negative regulation of cellular macromolecule biosynthetic process
|
GO:2000113 |
267 |
0.095
|
|
|
|
negative regulation of cellular biosynthetic process
|
GO:0031327 |
277 |
0.089
|
|
|
|
chromatin organization
|
GO:0006325 |
207 |
0.072
|
|
|
|
negative regulation of cellular metabolic process
|
GO:0031324 |
382 |
0.070
|
|
|
|
negative regulation of nucleic acid templated transcription
|
GO:1903507 |
240 |
0.062
|
|
|
|
chromosome organization
|
GO:0051276 |
360 |
0.059
|
|
|
|
protein modification process
|
GO:0036211 |
438 |
0.057
|
|
|
|
negative regulation of cell communication
|
GO:0010648 |
223 |
0.056
|
|
|
|
cellular protein modification process
|
GO:0006464 |
438 |
0.054
|
|
|
|
regulation of intracellular signal transduction
|
GO:1902531 |
236 |
0.051
|
|
|
|
establishment or maintenance of cell polarity
|
GO:0007163 |
167 |
0.047
|
|
|
|
germ line stem cell maintenance
|
GO:0030718 |
50 |
0.046
|
|
|
|
imaginal disc derived appendage development
|
GO:0048737 |
399 |
0.046
|
|
|
|
negative regulation of rna metabolic process
|
GO:0051253 |
251 |
0.044
|
|
|
|
negative regulation of biosynthetic process
|
GO:0009890 |
277 |
0.044
|
|
|
|
negative regulation of signal transduction
|
GO:0009968 |
206 |
0.043
|
|
|
|
dna metabolic process
|
GO:0006259 |
227 |
0.043
|
|
|
|
wing disc morphogenesis
|
GO:0007472 |
344 |
0.040
|
|
|
|
negative regulation of response to stimulus
|
GO:0048585 |
258 |
0.040
|
|
|
|
catabolic process
|
GO:0009056 |
409 |
0.040
|
|
|
|
negative regulation of rna biosynthetic process
|
GO:1902679 |
240 |
0.038
|
|
|
|
regulation of multicellular organismal development
|
GO:2000026 |
414 |
0.037
|
Fly |
|
|
post embryonic appendage morphogenesis
|
GO:0035120 |
385 |
0.037
|
|
|
|
cellular response to external stimulus
|
GO:0071496 |
66 |
0.036
|
|
|
|
imaginal disc derived appendage morphogenesis
|
GO:0035114 |
395 |
0.035
|
|
|
|
regulation of localization
|
GO:0032879 |
275 |
0.035
|
|
|
|
nuclear division
|
GO:0000280 |
332 |
0.035
|
|
|
|
regionalization
|
GO:0003002 |
416 |
0.033
|
|
|
|
negative regulation of developmental process
|
GO:0051093 |
201 |
0.032
|
|
|
|
appendage development
|
GO:0048736 |
401 |
0.032
|
|
|
|
cell proliferation
|
GO:0008283 |
299 |
0.031
|
|
|
|
transcription from rna polymerase ii promoter
|
GO:0006366 |
368 |
0.031
|
Fly |
|
|
regulation of transcription from rna polymerase ii promoter
|
GO:0006357 |
378 |
0.030
|
Fly |
|
|
imaginal disc derived wing morphogenesis
|
GO:0007476 |
337 |
0.030
|
|
|
|
regulation of cell cycle
|
GO:0051726 |
291 |
0.030
|
|
|
|
stem cell differentiation
|
GO:0048863 |
117 |
0.030
|
|
|
|
appendage morphogenesis
|
GO:0035107 |
397 |
0.030
|
|
|
|
positive regulation of response to stimulus
|
GO:0048584 |
323 |
0.029
|
|
|
|
regulation of phosphate metabolic process
|
GO:0019220 |
210 |
0.029
|
|
|
|
positive regulation of signaling
|
GO:0023056 |
243 |
0.028
|
|
|
|
cellular response to extracellular stimulus
|
GO:0031668 |
64 |
0.028
|
|
|
|
positive regulation of biosynthetic process
|
GO:0009891 |
316 |
0.028
|
Fly |
|
|
positive regulation of cell communication
|
GO:0010647 |
250 |
0.028
|
|
|
|
cellular catabolic process
|
GO:0044248 |
372 |
0.027
|
|
|
|
cellularization
|
GO:0007349 |
90 |
0.027
|
|
|
|
regulation of cell cycle process
|
GO:0010564 |
181 |
0.027
|
|
|
|
protein modification by small protein conjugation or removal
|
GO:0070647 |
106 |
0.026
|
|
|
|
organic substance catabolic process
|
GO:1901575 |
308 |
0.026
|
|
|
|
mitotic nuclear division
|
GO:0007067 |
213 |
0.026
|
|
|
|
establishment of localization in cell
|
GO:0051649 |
402 |
0.026
|
|
|
|
phosphorylation
|
GO:0016310 |
294 |
0.026
|
|
|
|
intracellular signal transduction
|
GO:0035556 |
300 |
0.026
|
|
|
|
organonitrogen compound metabolic process
|
GO:1901564 |
318 |
0.025
|
|
|
|
protein ubiquitination
|
GO:0016567 |
70 |
0.025
|
|
|
|
positive regulation of signal transduction
|
GO:0009967 |
223 |
0.025
|
|
|
|
protein phosphorylation
|
GO:0006468 |
169 |
0.025
|
|
|
|
positive regulation of macromolecule metabolic process
|
GO:0010604 |
405 |
0.025
|
Fly |
|
|
regulation of cellular protein metabolic process
|
GO:0032268 |
243 |
0.025
|
|
|
|
cellular ketone metabolic process
|
GO:0042180 |
24 |
0.025
|
|
|
|
amine metabolic process
|
GO:0009308 |
12 |
0.024
|
|
|
|
regulation of cellular ketone metabolic process
|
GO:0010565 |
3 |
0.023
|
|
|
|
regulation of cellular amino acid metabolic process
|
GO:0006521 |
0 |
0.023
|
|
|
|
homeostatic process
|
GO:0042592 |
199 |
0.023
|
|
|
|
death
|
GO:0016265 |
284 |
0.023
|
|
|
|
cell division
|
GO:0051301 |
248 |
0.023
|
|
|
|
protein modification by small protein conjugation
|
GO:0032446 |
79 |
0.022
|
|
|
|
organophosphate metabolic process
|
GO:0019637 |
195 |
0.022
|
|
|
|
negative regulation of intracellular signal transduction
|
GO:1902532 |
57 |
0.022
|
|
|
|
locomotory behavior
|
GO:0007626 |
176 |
0.022
|
|
|
|
regulation of protein metabolic process
|
GO:0051246 |
256 |
0.021
|
|
|
|
growth
|
GO:0040007 |
359 |
0.021
|
|
|
|
cellular amine metabolic process
|
GO:0044106 |
12 |
0.021
|
|
|
|
stem cell development
|
GO:0048864 |
79 |
0.021
|
|
|
|
regulation of phosphorus metabolic process
|
GO:0051174 |
210 |
0.021
|
|
|
|
tissue morphogenesis
|
GO:0048729 |
297 |
0.021
|
|
|
|
negative regulation of cell differentiation
|
GO:0045596 |
143 |
0.020
|
|
|
|
positive regulation of rna metabolic process
|
GO:0051254 |
271 |
0.020
|
Fly |
|
|
positive regulation of macromolecule biosynthetic process
|
GO:0010557 |
283 |
0.020
|
Fly |
|
|
central nervous system development
|
GO:0007417 |
201 |
0.020
|
|
|
|
endocytosis
|
GO:0006897 |
310 |
0.020
|
|
|
|
embryonic axis specification
|
GO:0000578 |
107 |
0.020
|
|
|
|
epithelial cell differentiation
|
GO:0030855 |
322 |
0.020
|
|
|
|
negative regulation of signaling
|
GO:0023057 |
219 |
0.020
|
|
|
|
positive regulation of cellular protein metabolic process
|
GO:0032270 |
118 |
0.020
|
|
|
|
regulation of response to stress
|
GO:0080134 |
200 |
0.019
|
|
|
|
regulation of phosphorylation
|
GO:0042325 |
147 |
0.019
|
|
|
|
tube morphogenesis
|
GO:0035239 |
191 |
0.019
|
|
|
|
carboxylic acid metabolic process
|
GO:0019752 |
92 |
0.019
|
|
|
|
nucleotide metabolic process
|
GO:0009117 |
161 |
0.019
|
|
|
|
ovarian follicle cell development
|
GO:0030707 |
248 |
0.019
|
|
|
|
regulation of molecular function
|
GO:0065009 |
217 |
0.019
|
|
|
|
small molecule metabolic process
|
GO:0044281 |
305 |
0.018
|
|
|
|
proteolysis
|
GO:0006508 |
192 |
0.018
|
|
|
|
positive regulation of rna biosynthetic process
|
GO:1902680 |
266 |
0.018
|
Fly |
|
|
segmentation
|
GO:0035282 |
207 |
0.018
|
|
|
|
regulation of cellular amine metabolic process
|
GO:0033238 |
3 |
0.018
|
|
|
|
body morphogenesis
|
GO:0010171 |
2 |
0.018
|
|
|
|
anatomical structure homeostasis
|
GO:0060249 |
97 |
0.018
|
|
|
|
macromolecule catabolic process
|
GO:0009057 |
161 |
0.018
|
|
|
|
cell death
|
GO:0008219 |
279 |
0.018
|
|
|
|
developmental growth
|
GO:0048589 |
280 |
0.017
|
|
|
|
posttranscriptional regulation of gene expression
|
GO:0010608 |
145 |
0.017
|
|
|
|
nucleoside phosphate metabolic process
|
GO:0006753 |
162 |
0.017
|
|
|
|
single organism behavior
|
GO:0044708 |
391 |
0.017
|
Fly |
|
|
response to organic substance
|
GO:0010033 |
284 |
0.017
|
|
|
|
signal transduction by phosphorylation
|
GO:0023014 |
107 |
0.017
|
|
|
|
neurological system process
|
GO:0050877 |
358 |
0.017
|
Fly |
|
|
heterochromatin organization
|
GO:0070828 |
25 |
0.017
|
|
|
|
mapk cascade
|
GO:0000165 |
107 |
0.017
|
|
|
|
morphogenesis of an epithelium
|
GO:0002009 |
276 |
0.017
|
|
|
|
purine ribonucleotide metabolic process
|
GO:0009150 |
145 |
0.016
|
|
|
|
cellular macromolecular complex assembly
|
GO:0034622 |
153 |
0.016
|
|
|
|
regulation of mitotic cell cycle
|
GO:0007346 |
190 |
0.016
|
|
|
|
erk1 and erk2 cascade
|
GO:0070371 |
39 |
0.016
|
|
|
|
regulation of growth
|
GO:0040008 |
233 |
0.016
|
|
|
|
columnar cuboidal epithelial cell differentiation
|
GO:0002065 |
256 |
0.016
|
|
|
|
single organism biosynthetic process
|
GO:0044711 |
206 |
0.016
|
|
|
|
cellular macromolecule catabolic process
|
GO:0044265 |
136 |
0.016
|
|
|
|
stem cell maintenance
|
GO:0019827 |
67 |
0.015
|
|
|
|
small gtpase mediated signal transduction
|
GO:0007264 |
88 |
0.015
|
|
|
|
organonitrogen compound catabolic process
|
GO:1901565 |
128 |
0.015
|
|
|
|
regulation of anatomical structure morphogenesis
|
GO:0022603 |
242 |
0.015
|
|
|
|
columnar cuboidal epithelial cell development
|
GO:0002066 |
249 |
0.015
|
|
|
|
response to abiotic stimulus
|
GO:0009628 |
341 |
0.015
|
|
|
|
oxoacid metabolic process
|
GO:0043436 |
103 |
0.015
|
|
|
|
purine containing compound catabolic process
|
GO:0072523 |
112 |
0.015
|
|
|
|
positive regulation of phosphorus metabolic process
|
GO:0010562 |
139 |
0.015
|
|
|
|
axis specification
|
GO:0009798 |
167 |
0.015
|
|
|
|
positive regulation of protein metabolic process
|
GO:0051247 |
128 |
0.014
|
|
|
|
positive regulation of transcription dna templated
|
GO:0045893 |
266 |
0.014
|
Fly |
|
|
vesicle mediated transport
|
GO:0016192 |
381 |
0.014
|
|
|
|
organic acid metabolic process
|
GO:0006082 |
103 |
0.014
|
|
|
|
nucleoside triphosphate metabolic process
|
GO:0009141 |
120 |
0.014
|
|
|
|
programmed cell death
|
GO:0012501 |
257 |
0.014
|
|
|
|
ras protein signal transduction
|
GO:0007265 |
88 |
0.014
|
|
|
|
purine nucleotide metabolic process
|
GO:0006163 |
146 |
0.014
|
|
|
|
cellular amino acid metabolic process
|
GO:0006520 |
61 |
0.014
|
|
|
|
positive regulation of intracellular signal transduction
|
GO:1902533 |
116 |
0.014
|
|
|
|
negative regulation of phosphorus metabolic process
|
GO:0010563 |
45 |
0.014
|
|
|
|
neuroblast proliferation
|
GO:0007405 |
74 |
0.014
|
|
|
|
organelle fission
|
GO:0048285 |
340 |
0.014
|
|
|
|
regulation of transport
|
GO:0051049 |
181 |
0.014
|
|
|
|
phagocytosis
|
GO:0006909 |
215 |
0.014
|
|
|
|
nucleobase containing small molecule metabolic process
|
GO:0055086 |
174 |
0.013
|
|
|
|
cell cell signaling involved in cell fate commitment
|
GO:0045168 |
210 |
0.013
|
|
|
|
g protein coupled receptor signaling pathway
|
GO:0007186 |
136 |
0.013
|
|
|
|
negative regulation of erk1 and erk2 cascade
|
GO:0070373 |
3 |
0.013
|
|
|
|
positive regulation of phosphate metabolic process
|
GO:0045937 |
139 |
0.013
|
|
|
|
brain development
|
GO:0007420 |
120 |
0.013
|
|
|
|
nucleoside triphosphate catabolic process
|
GO:0009143 |
108 |
0.013
|
|
|
|
developmental maturation
|
GO:0021700 |
172 |
0.013
|
|
|
|
tube development
|
GO:0035295 |
244 |
0.013
|
|
|
|
positive regulation of cellular amine metabolic process
|
GO:0033240 |
0 |
0.013
|
|
|
|
positive regulation of transcription from rna polymerase ii promoter
|
GO:0045944 |
204 |
0.013
|
Fly |
|
|
purine nucleoside catabolic process
|
GO:0006152 |
112 |
0.013
|
|
|
|
protein complex assembly
|
GO:0006461 |
200 |
0.013
|
|
|
|
gland development
|
GO:0048732 |
191 |
0.013
|
|
|
|
organic cyclic compound catabolic process
|
GO:1901361 |
168 |
0.013
|
|
|
|
head development
|
GO:0060322 |
135 |
0.013
|
|
|
|
sensory perception of pain
|
GO:0019233 |
4 |
0.013
|
|
|
|
regulation of programmed cell death
|
GO:0043067 |
152 |
0.013
|
|
|
|
protein localization
|
GO:0008104 |
284 |
0.013
|
|
|
|
regulation of mapk cascade
|
GO:0043408 |
92 |
0.013
|
|
|
|
cell maturation
|
GO:0048469 |
144 |
0.012
|
|
|
|
anterior posterior axis specification embryo
|
GO:0008595 |
103 |
0.012
|
|
|
|
mitotic cell cycle phase transition
|
GO:0044772 |
138 |
0.012
|
|
|
|
purine ribonucleoside triphosphate catabolic process
|
GO:0009207 |
108 |
0.012
|
|
|
|
negative regulation of phosphate metabolic process
|
GO:0045936 |
45 |
0.012
|
|
|
|
ribonucleotide metabolic process
|
GO:0009259 |
145 |
0.012
|
|
|
|
tripartite regional subdivision
|
GO:0007351 |
103 |
0.012
|
|
|
|
organelle localization
|
GO:0051640 |
148 |
0.012
|
|
|
|
cellular response to organic substance
|
GO:0071310 |
132 |
0.012
|
|
|
|
cellular nitrogen compound catabolic process
|
GO:0044270 |
165 |
0.012
|
|
|
|
positive regulation of gene expression
|
GO:0010628 |
290 |
0.012
|
Fly |
|
|
response to extracellular stimulus
|
GO:0009991 |
116 |
0.012
|
|
|
|
nucleobase containing compound catabolic process
|
GO:0034655 |
165 |
0.012
|
|
|
|
dorsal ventral pattern formation
|
GO:0009953 |
133 |
0.012
|
|
|
|
regulation of organelle organization
|
GO:0033043 |
196 |
0.012
|
|
|
|
positive regulation of cellular biosynthetic process
|
GO:0031328 |
316 |
0.012
|
Fly |
|
|
salivary gland morphogenesis
|
GO:0007435 |
145 |
0.012
|
|
|
|
establishment of protein localization
|
GO:0045184 |
163 |
0.012
|
|
|
|
regulation of cell development
|
GO:0060284 |
215 |
0.012
|
Fly |
|
|
negative regulation of cellular component organization
|
GO:0051129 |
108 |
0.011
|
|
|
|
multicellular organismal aging
|
GO:0010259 |
140 |
0.011
|
|
|
|
carbohydrate derivative catabolic process
|
GO:1901136 |
118 |
0.011
|
|
|
|
dendrite development
|
GO:0016358 |
204 |
0.011
|
Fly |
|
|
response to lipopolysaccharide
|
GO:0032496 |
4 |
0.011
|
|
|
|
neuronal stem cell division
|
GO:0036445 |
35 |
0.011
|
|
|
|
compound eye development
|
GO:0048749 |
307 |
0.011
|
|
|
|
positive regulation of nucleic acid templated transcription
|
GO:1903508 |
266 |
0.011
|
Fly |
|
|
anterior posterior axis specification
|
GO:0009948 |
109 |
0.011
|
|
|
|
blastoderm segmentation
|
GO:0007350 |
159 |
0.011
|
|
|
|
immune system process
|
GO:0002376 |
347 |
0.011
|
|
|
|
positive regulation of cellular component organization
|
GO:0051130 |
156 |
0.011
|
|
|
|
negative regulation of cell cycle
|
GO:0045786 |
116 |
0.011
|
|
|
|
regulation of translation
|
GO:0006417 |
56 |
0.011
|
|
|
|
response to organophosphorus
|
GO:0046683 |
2 |
0.011
|
|
|
|
embryonic development via the syncytial blastoderm
|
GO:0001700 |
148 |
0.011
|
|
|
|
purine ribonucleoside metabolic process
|
GO:0046128 |
127 |
0.011
|
|
|
|
regulation of protein modification process
|
GO:0031399 |
112 |
0.011
|
|
|
|
nucleoside metabolic process
|
GO:0009116 |
127 |
0.011
|
|
|
|
negative regulation of cellular protein metabolic process
|
GO:0032269 |
85 |
0.011
|
|
|
|
single organism cellular localization
|
GO:1902580 |
180 |
0.011
|
|
|
|
photoreceptor cell differentiation
|
GO:0046530 |
170 |
0.011
|
|
|
|
aging
|
GO:0007568 |
143 |
0.011
|
|
|
|
digestive tract development
|
GO:0048565 |
149 |
0.011
|
|
|
|
heterocycle catabolic process
|
GO:0046700 |
166 |
0.011
|
|
|
|
response to oxygen containing compound
|
GO:1901700 |
200 |
0.011
|
|
|
|
regulation of erk1 and erk2 cascade
|
GO:0070372 |
39 |
0.011
|
|
|
|
macromolecular complex assembly
|
GO:0065003 |
256 |
0.011
|
|
|
|
carbohydrate derivative metabolic process
|
GO:1901135 |
217 |
0.011
|
|
|
|
positive regulation of nitrogen compound metabolic process
|
GO:0051173 |
354 |
0.011
|
Fly |
|
|
purine ribonucleoside catabolic process
|
GO:0046130 |
112 |
0.011
|
|
|
|
modification dependent macromolecule catabolic process
|
GO:0043632 |
79 |
0.010
|
|
|
|
regulation of catabolic process
|
GO:0009894 |
170 |
0.010
|
|
|
|
ribonucleotide catabolic process
|
GO:0009261 |
109 |
0.010
|
|
|
|
asymmetric stem cell division
|
GO:0098722 |
49 |
0.010
|
|
|
|
negative regulation of mitotic cell cycle
|
GO:0045930 |
109 |
0.010
|
|
|
|
purine nucleoside triphosphate metabolic process
|
GO:0009144 |
119 |
0.010
|
|
|
|
defense response
|
GO:0006952 |
300 |
0.010
|
|
|
|
regulation of apoptotic process
|
GO:0042981 |
130 |
0.010
|
|
|
|
positive regulation of peptidyl tyrosine phosphorylation
|
GO:0050731 |
4 |
0.010
|
|
|
|
regulation of mitotic cell cycle phase transition
|
GO:1901990 |
130 |
0.010
|
|
|
|
regulation of notch signaling pathway
|
GO:0008593 |
100 |
0.010
|
|
|
|
digestive tract morphogenesis
|
GO:0048546 |
127 |
0.010
|
|
|
|
chromatin modification
|
GO:0016568 |
147 |
0.010
|
|
|
|
positive regulation of phosphorylation
|
GO:0042327 |
87 |
0.010
|
|
|
|
lateral inhibition
|
GO:0046331 |
206 |
0.010
|
|
|
|
g2 dna damage checkpoint
|
GO:0031572 |
69 |
0.010
|
|
|
|
purine containing compound metabolic process
|
GO:0072521 |
155 |
0.010
|
|
|
|
regulation of catalytic activity
|
GO:0050790 |
185 |
0.010
|
|
|
|
epithelial cell development
|
GO:0002064 |
274 |
0.010
|
|
|
|
salivary gland development
|
GO:0007431 |
162 |
0.010
|
|
|
|
regulation of cell death
|
GO:0010941 |
173 |
0.010
|
|
|
|
asymmetric neuroblast division
|
GO:0055059 |
33 |
0.010
|
|
|
|
carbohydrate derivative biosynthetic process
|
GO:1901137 |
85 |
0.010
|
|