Drosophila melanogaster

32 known processes

MESR6 (Dmel_CG6818)

Misexpression suppressor of ras 6

(Aliases: CG6818,Dmel\CG6818)

MESR6 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
eye development GO:0001654 323 0.104
positive regulation of macromolecule metabolic process GO:0010604 405 0.099
negative regulation of cellular metabolic process GO:0031324 382 0.091
mitotic dna integrity checkpoint GO:0044774 75 0.077
sensory organ morphogenesis GO:0090596 260 0.077
mitotic dna damage checkpoint GO:0044773 74 0.073
cell cell signaling involved in cell fate commitment GO:0045168 210 0.066
positive regulation of macromolecule biosynthetic process GO:0010557 283 0.064
sensory perception GO:0007600 196 0.063
positive regulation of cellular protein metabolic process GO:0032270 118 0.061
proteolysis GO:0006508 192 0.060
negative regulation of response to stimulus GO:0048585 258 0.060
positive regulation of gene expression GO:0010628 290 0.059
eye morphogenesis GO:0048592 260 0.059
lateral inhibition GO:0046331 206 0.059
cellular catabolic process GO:0044248 372 0.059
secondary metabolic process GO:0019748 75 0.058
macromolecular complex assembly GO:0065003 256 0.058
positive regulation of rna metabolic process GO:0051254 271 0.057
organic substance catabolic process GO:1901575 308 0.057
intracellular signal transduction GO:0035556 300 0.055
organonitrogen compound metabolic process GO:1901564 318 0.055
compound eye development GO:0048749 307 0.054
organic acid metabolic process GO:0006082 103 0.052
positive regulation of rna biosynthetic process GO:1902680 266 0.051
regulation of protein metabolic process GO:0051246 256 0.051
immune system process GO:0002376 347 0.050
mitotic cell cycle checkpoint GO:0007093 88 0.049
mitotic cell cycle phase transition GO:0044772 138 0.049
response to external biotic stimulus GO:0043207 293 0.049
protein modification process GO:0036211 438 0.048
positive regulation of peptidase activity GO:0010952 29 0.047
positive regulation of signal transduction GO:0009967 223 0.045
regulation of immune system process GO:0002682 176 0.045
dna integrity checkpoint GO:0031570 81 0.045
male gamete generation GO:0048232 201 0.045
compound eye morphogenesis GO:0001745 249 0.044
protein complex biogenesis GO:0070271 201 0.043
response to organic substance GO:0010033 284 0.042
negative regulation of biosynthetic process GO:0009890 277 0.042
negative regulation of signaling GO:0023057 219 0.041
regulation of cell cycle GO:0051726 291 0.041
phosphorylation GO:0016310 294 0.041
response to nutrient levels GO:0031667 114 0.041
vesicle mediated transport GO:0016192 381 0.040
defense response to bacterium GO:0042742 178 0.040
response to mercury ion GO:0046689 3 0.040
positive regulation of compound eye retinal cell programmed cell death GO:0046672 9 0.039
photoreceptor cell differentiation GO:0046530 170 0.039
carboxylic acid metabolic process GO:0019752 92 0.038
response to organophosphorus GO:0046683 2 0.038
catabolic process GO:0009056 409 0.037
actin cytoskeleton organization GO:0030036 206 0.037
small molecule metabolic process GO:0044281 305 0.036
regulation of multicellular organismal development GO:2000026 414 0.036
regulation of cellular protein metabolic process GO:0032268 243 0.035
protein modification by small protein conjugation or removal GO:0070647 106 0.035
activation of cysteine type endopeptidase activity GO:0097202 17 0.035
forebrain development GO:0030900 2 0.034
establishment of localization in cell GO:0051649 402 0.034
eye photoreceptor cell differentiation GO:0001754 145 0.034
positive regulation of biosynthetic process GO:0009891 316 0.033
regulation of transport GO:0051049 181 0.033
macromolecule catabolic process GO:0009057 161 0.033
regulation of tube size GO:0035150 46 0.033
synaptic transmission GO:0007268 288 0.033
epithelial cell differentiation GO:0030855 322 0.033
negative regulation of cell cycle GO:0045786 116 0.032
aging GO:0007568 143 0.032
autophagic cell death GO:0048102 83 0.032
negative regulation of nitrogen compound metabolic process GO:0051172 265 0.032
response to radiation GO:0009314 155 0.031
negative regulation of signal transduction GO:0009968 206 0.031
regulation of anatomical structure morphogenesis GO:0022603 242 0.031
positive regulation of nucleic acid templated transcription GO:1903508 266 0.031
cell motility GO:0048870 251 0.030
death GO:0016265 284 0.030
cellular response to dna damage stimulus GO:0006974 223 0.030
endocytosis GO:0006897 310 0.030
single organism catabolic process GO:0044712 228 0.030
neurological system process GO:0050877 358 0.029
regulation of response to external stimulus GO:0032101 115 0.029
er nucleus signaling pathway GO:0006984 9 0.029
defense response GO:0006952 300 0.029
positive regulation of apoptotic signaling pathway GO:2001235 4 0.029
innate immune response GO:0045087 144 0.029
organelle assembly GO:0070925 198 0.029
positive regulation of protein metabolic process GO:0051247 128 0.029
cellular protein modification process GO:0006464 438 0.028
salivary gland histolysis GO:0035070 88 0.028
modification dependent macromolecule catabolic process GO:0043632 79 0.028
cellular response to chemical stimulus GO:0070887 199 0.028
organic substance transport GO:0071702 257 0.028
programmed cell death GO:0012501 257 0.028
appendage morphogenesis GO:0035107 397 0.028
developmental maturation GO:0021700 172 0.028
regulation of programmed cell death GO:0043067 152 0.027
regulation of phosphate metabolic process GO:0019220 210 0.027
spermatogenesis GO:0007283 200 0.027
negative regulation of cell communication GO:0010648 223 0.027
cellular macromolecular complex assembly GO:0034622 153 0.027
positive regulation of cellular biosynthetic process GO:0031328 316 0.027
growth GO:0040007 359 0.026
cell maturation GO:0048469 144 0.026
secretion GO:0046903 109 0.026
developmental programmed cell death GO:0010623 138 0.026
positive regulation of transcription dna templated GO:0045893 266 0.026
small gtpase mediated signal transduction GO:0007264 88 0.026
central nervous system development GO:0007417 201 0.025
cellular response to sterol depletion GO:0071501 3 0.025
tissue morphogenesis GO:0048729 297 0.025
response to starvation GO:0042594 97 0.025
xenobiotic catabolic process GO:0042178 1 0.025
cellular protein catabolic process GO:0044257 83 0.025
regulation of localization GO:0032879 275 0.025
organonitrogen compound catabolic process GO:1901565 128 0.025
apoptotic process GO:0006915 159 0.025
regulation of apoptotic process GO:0042981 130 0.025
axon development GO:0061564 297 0.025
regulation of catalytic activity GO:0050790 185 0.024
epithelial cell development GO:0002064 274 0.024
negative regulation of mitotic cell cycle GO:0045930 109 0.024
positive regulation of transcription from rna polymerase ii promoter GO:0045944 204 0.024
cell death GO:0008219 279 0.024
cellularization GO:0007349 90 0.024
protein complex assembly GO:0006461 200 0.024
multicellular organismal aging GO:0010259 140 0.023
cellular macromolecule catabolic process GO:0044265 136 0.023
steroid catabolic process GO:0006706 1 0.023
response to lipopolysaccharide GO:0032496 4 0.023
mapk cascade GO:0000165 107 0.023
regulation of catabolic process GO:0009894 170 0.023
negative regulation of cell cycle process GO:0010948 109 0.023
camera type eye development GO:0043010 4 0.023
response to light stimulus GO:0009416 124 0.023
body morphogenesis GO:0010171 2 0.023
positive regulation of i kappab kinase nf kappab signaling GO:0043123 1 0.023
ameboidal type cell migration GO:0001667 151 0.023
activation of cysteine type endopeptidase activity involved in apoptotic process GO:0006919 16 0.022
embryonic morphogenesis GO:0048598 206 0.022
regulation of cellular localization GO:0060341 136 0.022
positive regulation of nucleobase containing compound metabolic process GO:0045935 332 0.022
multi organism behavior GO:0051705 175 0.022
regulation of cellular catabolic process GO:0031329 157 0.022
positive regulation of cell communication GO:0010647 250 0.022
dna damage checkpoint GO:0000077 78 0.022
positive regulation of signaling GO:0023056 243 0.022
response to abiotic stimulus GO:0009628 341 0.022
regulation of mitotic cell cycle phase transition GO:1901990 130 0.022
morphogenesis of an epithelium GO:0002009 276 0.022
establishment or maintenance of apical basal cell polarity GO:0035088 34 0.021
negative regulation of cell cycle phase transition GO:1901988 103 0.021
imaginal disc derived appendage development GO:0048737 399 0.021
ribonucleoside metabolic process GO:0009119 127 0.021
salivary gland cell autophagic cell death GO:0035071 83 0.021
regulation of mitotic cell cycle GO:0007346 190 0.021
positive regulation of response to stimulus GO:0048584 323 0.021
connective tissue development GO:0061448 3 0.020
regulation of molecular function GO:0065009 217 0.020
positive regulation of nitrogen compound metabolic process GO:0051173 354 0.020
axon guidance GO:0007411 233 0.020
regulation of defense response GO:0031347 102 0.020
peptide metabolic process GO:0006518 80 0.020
regulation of cell cycle phase transition GO:1901987 130 0.020
regionalization GO:0003002 416 0.020
gland morphogenesis GO:0022612 145 0.020
sensory perception of chemical stimulus GO:0007606 116 0.020
regulation of cellular response to stress GO:0080135 89 0.019
insecticide catabolic process GO:0046701 1 0.019
exocrine system development GO:0035272 162 0.019
protein transport GO:0015031 155 0.019
response to wounding GO:0009611 94 0.019
regulation of cellular amino acid metabolic process GO:0006521 0 0.019
regulation of cell development GO:0060284 215 0.019
appendage development GO:0048736 401 0.019
protein catabolic process GO:0030163 101 0.019
protein maturation GO:0051604 71 0.019
negative regulation of developmental process GO:0051093 201 0.019
regulation of ras protein signal transduction GO:0046578 93 0.019
response to bacterium GO:0009617 198 0.019
defense response to other organism GO:0098542 225 0.019
protein phosphorylation GO:0006468 169 0.019
regulation of protein transport GO:0051223 57 0.018
regulation of small gtpase mediated signal transduction GO:0051056 93 0.018
columnar cuboidal epithelial cell development GO:0002066 249 0.018
response to oxygen containing compound GO:1901700 200 0.018
cellular response to organic substance GO:0071310 132 0.018
response to endogenous stimulus GO:0009719 119 0.018
pigment metabolic process GO:0042440 84 0.018
spermatid differentiation GO:0048515 114 0.018
lipid catabolic process GO:0016042 21 0.018
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 54 0.018
axis specification GO:0009798 167 0.018
cell cycle arrest GO:0007050 4 0.018
posttranscriptional regulation of gene expression GO:0010608 145 0.018
positive regulation of cell migration GO:0030335 2 0.018
immune response GO:0006955 246 0.018
intracellular transport GO:0046907 228 0.017
sensory perception of mechanical stimulus GO:0050954 72 0.017
regulation of hydrolase activity GO:0051336 97 0.017
salivary gland morphogenesis GO:0007435 145 0.017
cell migration GO:0016477 238 0.017
cellular amino acid metabolic process GO:0006520 61 0.017
tissue death GO:0016271 102 0.017
modification dependent protein catabolic process GO:0019941 78 0.017
ubiquitin dependent protein catabolic process GO:0006511 78 0.017
regulation of i kappab kinase nf kappab signaling GO:0043122 2 0.017
regulation of proteolysis GO:0030162 87 0.017
positive regulation of cell death GO:0010942 69 0.017
histolysis GO:0007559 102 0.017
protein modification by small protein removal GO:0070646 28 0.017
protein modification by small protein conjugation GO:0032446 79 0.017
gland development GO:0048732 191 0.017
sensory perception of smell GO:0007608 80 0.017
ras protein signal transduction GO:0007265 88 0.017
cellular response to extracellular stimulus GO:0031668 64 0.017
autophagy GO:0006914 108 0.017
photoreceptor cell development GO:0042461 96 0.017
regulation of cellular amine metabolic process GO:0033238 3 0.017
transcription from rna polymerase ii promoter GO:0006366 368 0.017
positive regulation of molecular function GO:0044093 136 0.017
regulation of phosphorus metabolic process GO:0051174 210 0.017
defense response to gram negative bacterium GO:0050829 94 0.017
phenol containing compound metabolic process GO:0018958 57 0.017
extrinsic apoptotic signaling pathway GO:0097191 1 0.017
negative regulation of cellular biosynthetic process GO:0031327 277 0.016
developmental growth GO:0048589 280 0.016
positive regulation of production of molecular mediator of immune response GO:0002702 28 0.016
taxis GO:0042330 304 0.016
neuron projection guidance GO:0097485 241 0.016
regulation of transcription from rna polymerase ii promoter GO:0006357 378 0.016
er associated ubiquitin dependent protein catabolic process GO:0030433 3 0.016
establishment or maintenance of polarity of follicular epithelium GO:0016334 26 0.016
regulation of cell death GO:0010941 173 0.016
cell junction organization GO:0034330 57 0.016
cellular nitrogen compound catabolic process GO:0044270 165 0.016
protein heterooligomerization GO:0051291 4 0.016
oxoacid metabolic process GO:0043436 103 0.016
proteolysis involved in cellular protein catabolic process GO:0051603 83 0.016
immune effector process GO:0002252 98 0.016
negative regulation of cell death GO:0060548 81 0.016
regulation of organ morphogenesis GO:2000027 78 0.016
regulation of developmental growth GO:0048638 174 0.016
negative regulation of gene expression GO:0010629 387 0.015
regulation of cellular ketone metabolic process GO:0010565 3 0.015
regulation of intracellular signal transduction GO:1902531 236 0.015
positive regulation of intracellular signal transduction GO:1902533 116 0.015
cell cycle checkpoint GO:0000075 95 0.015
antimicrobial peptide production GO:0002775 46 0.015
actin filament based process GO:0030029 220 0.015
cation transport GO:0006812 110 0.015
multi organism reproductive behavior GO:0044705 121 0.015
pigmentation GO:0043473 75 0.015
negative regulation of multicellular organismal process GO:0051241 142 0.015
response to extracellular stimulus GO:0009991 116 0.015
response to unfolded protein GO:0006986 9 0.015
nuclear division GO:0000280 332 0.015
neuron remodeling GO:0016322 29 0.015
chemotaxis GO:0006935 249 0.015
positive regulation of cellular amide metabolic process GO:0034250 26 0.015
positive regulation of autophagy GO:0010508 21 0.015
positive regulation of transport GO:0051050 92 0.015
epithelium migration GO:0090132 148 0.015
cellular ketone metabolic process GO:0042180 24 0.014
regulation of cellular component biogenesis GO:0044087 201 0.014
enzyme linked receptor protein signaling pathway GO:0007167 179 0.014
determination of adult lifespan GO:0008340 137 0.014
phagocytosis GO:0006909 215 0.014
post embryonic appendage morphogenesis GO:0035120 385 0.014
single fertilization GO:0007338 24 0.014
establishment of organelle localization GO:0051656 122 0.014
maintenance of location GO:0051235 73 0.014
sulfur compound metabolic process GO:0006790 59 0.014
neuromuscular synaptic transmission GO:0007274 67 0.014
regulation of response to extracellular stimulus GO:0032104 18 0.014
defense response to virus GO:0051607 23 0.014
establishment of protein localization GO:0045184 163 0.014
cellular lipid metabolic process GO:0044255 83 0.014
cell cycle phase transition GO:0044770 140 0.014
amine metabolic process GO:0009308 12 0.014
protein localization GO:0008104 284 0.014
centrosome organization GO:0051297 163 0.014
positive regulation of cysteine type endopeptidase activity involved in apoptotic process GO:0043280 23 0.014
single organism biosynthetic process GO:0044711 206 0.014
regulation of autophagy GO:0010506 62 0.014
proteasomal protein catabolic process GO:0010498 59 0.014
melanin metabolic process GO:0006582 47 0.013
spermatid development GO:0007286 98 0.013
negative regulation of cellular macromolecule biosynthetic process GO:2000113 267 0.013
positive regulation of cellular component organization GO:0051130 156 0.013
positive regulation of hydrolase activity GO:0051345 78 0.013
oxidation reduction process GO:0055114 123 0.013
regulation of protein modification process GO:0031399 112 0.013
establishment or maintenance of cytoskeleton polarity GO:0030952 44 0.013
cognition GO:0050890 141 0.013
regulation of wnt signaling pathway GO:0030111 68 0.013
response to heat GO:0009408 63 0.013
amide biosynthetic process GO:0043604 42 0.013
positive regulation of catabolic process GO:0009896 105 0.013
regulation of cell differentiation GO:0045595 302 0.013
morphogenesis of follicular epithelium GO:0016333 36 0.013
single organism cellular localization GO:1902580 180 0.013
response to organonitrogen compound GO:0010243 75 0.013
negative regulation of rna metabolic process GO:0051253 251 0.013
memory GO:0007613 94 0.013
cell projection assembly GO:0030031 94 0.013
regulation of vesicle mediated transport GO:0060627 59 0.012
localization of cell GO:0051674 257 0.012
signal transduction by phosphorylation GO:0023014 107 0.012
columnar cuboidal epithelial cell differentiation GO:0002065 256 0.012
response to virus GO:0009615 28 0.012
cell adhesion GO:0007155 136 0.012
mesenchymal cell development GO:0014031 1 0.012
microtubule organizing center organization GO:0031023 168 0.012
protein processing GO:0016485 68 0.012
organic cyclic compound catabolic process GO:1901361 168 0.012
imaginal disc derived wing morphogenesis GO:0007476 337 0.012
positive regulation of cell motility GO:2000147 3 0.012
regulation of macroautophagy GO:0016241 15 0.012
organelle fission GO:0048285 340 0.012
positive regulation of catalytic activity GO:0043085 118 0.012
regulation of epithelial cell proliferation GO:0050678 4 0.012
purine nucleoside triphosphate catabolic process GO:0009146 108 0.012
membrane organization GO:0061024 112 0.012
cellular protein complex assembly GO:0043623 71 0.012
cellular homeostasis GO:0019725 80 0.012
positive regulation of programmed cell death GO:0043068 62 0.012
ion transport GO:0006811 145 0.012
protein ubiquitination GO:0016567 70 0.012
vitamin biosynthetic process GO:0009110 1 0.012
positive regulation of immune system process GO:0002684 68 0.012
purine ribonucleoside catabolic process GO:0046130 112 0.012
eye photoreceptor cell development GO:0042462 81 0.012
single organism behavior GO:0044708 391 0.012
regulation of compound eye retinal cell programmed cell death GO:0046669 18 0.012
cellular amine metabolic process GO:0044106 12 0.012
establishment of planar polarity GO:0001736 87 0.011
positive regulation of retinal cell programmed cell death GO:0046670 9 0.011
regulation of protein localization GO:0032880 76 0.011
positive regulation of antimicrobial humoral response GO:0002760 28 0.011
digestive tract morphogenesis GO:0048546 127 0.011
establishment or maintenance of cell polarity GO:0007163 167 0.011
cellular response to lipopolysaccharide GO:0071222 3 0.011
cuticle development GO:0042335 86 0.011
establishment of tissue polarity GO:0007164 87 0.011
regulation of growth GO:0040008 233 0.011
regulation of cysteine type endopeptidase activity GO:2000116 27 0.011
telencephalon development GO:0021537 2 0.011
intrinsic apoptotic signaling pathway GO:0097193 16 0.011
purine nucleoside catabolic process GO:0006152 112 0.011
regulation of defense response to bacterium GO:1900424 30 0.011
reproductive behavior GO:0019098 122 0.011
ribonucleoside catabolic process GO:0042454 112 0.011
response to temperature stimulus GO:0009266 106 0.011
positive regulation of phosphate metabolic process GO:0045937 139 0.011
positive regulation of proteolysis GO:0045862 52 0.011
hormone catabolic process GO:0042447 3 0.011
compound eye photoreceptor cell differentiation GO:0001751 140 0.011
positive regulation of humoral immune response GO:0002922 28 0.011
negative regulation of cellular component organization GO:0051129 108 0.011
camera type eye morphogenesis GO:0048593 2 0.011
cellular modified amino acid metabolic process GO:0006575 45 0.011
nurse cell apoptotic process GO:0045476 17 0.011
brain development GO:0007420 120 0.011
carbohydrate derivative metabolic process GO:1901135 217 0.011
vesicle organization GO:0016050 44 0.011
regulation of response to nutrient levels GO:0032107 18 0.011
mitotic cytokinesis GO:0000281 50 0.010
adult locomotory behavior GO:0008344 76 0.010
instar larval development GO:0002168 55 0.010
neuron maturation GO:0042551 31 0.010
regulation of defense response to virus GO:0050688 14 0.010
chromatin organization GO:0006325 207 0.010
regulation of synaptic transmission GO:0050804 69 0.010
positive regulation of antibacterial peptide production GO:0002803 20 0.010
cellular response to abiotic stimulus GO:0071214 58 0.010
regulation of endopeptidase activity GO:0052548 36 0.010
purine containing compound metabolic process GO:0072521 155 0.010
establishment of vesicle localization GO:0051650 51 0.010
sperm individualization GO:0007291 48 0.010
ovarian follicle cell development GO:0030707 248 0.010
membrane depolarization GO:0051899 4 0.010
regulation of response to stress GO:0080134 200 0.010
response to endoplasmic reticulum stress GO:0034976 28 0.010
positive regulation of neuron apoptotic process GO:0043525 1 0.010
neuromuscular junction development GO:0007528 149 0.010
positive regulation of multicellular organismal process GO:0051240 143 0.010
regulation of peptidase activity GO:0052547 39 0.010
septate junction assembly GO:0019991 26 0.010
response to topologically incorrect protein GO:0035966 10 0.010
cellular macromolecule localization GO:0070727 220 0.010

MESR6 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.043
cardiovascular system disease DOID:1287 0 0.023
nervous system disease DOID:863 0 0.014
hypertension DOID:10763 0 0.013
vascular disease DOID:178 0 0.013
artery disease DOID:0050828 0 0.013