Drosophila melanogaster

77 known processes

Brf (Dmel_CG31256)

CG31256 gene product from transcript CG31256-RA

(Aliases: CG5419,Dmel\CG31256,CG31256,TFIIIB,BRF,BRF1,CG4155)

Brf biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
wing disc morphogenesis GO:0007472 344 0.130
appendage development GO:0048736 401 0.112
organonitrogen compound metabolic process GO:1901564 318 0.110
g2 dna damage checkpoint GO:0031572 69 0.096
imaginal disc derived appendage development GO:0048737 399 0.089
mitotic g2 m transition checkpoint GO:0044818 70 0.088
post embryonic appendage morphogenesis GO:0035120 385 0.085
regionalization GO:0003002 416 0.081
cellular macromolecule localization GO:0070727 220 0.079
imaginal disc derived appendage morphogenesis GO:0035114 395 0.076
endomembrane system organization GO:0010256 119 0.076
positive regulation of nucleobase containing compound metabolic process GO:0045935 332 0.074
nuclear division GO:0000280 332 0.068
protein transport GO:0015031 155 0.068
protein localization GO:0008104 284 0.068
establishment of localization in cell GO:0051649 402 0.067
mitotic cell cycle checkpoint GO:0007093 88 0.061
imaginal disc derived wing morphogenesis GO:0007476 337 0.060
epithelial cell differentiation GO:0030855 322 0.058
catabolic process GO:0009056 409 0.057
response to external biotic stimulus GO:0043207 293 0.057
carbohydrate derivative metabolic process GO:1901135 217 0.055
innate immune response GO:0045087 144 0.055
positive regulation of transcription from rna polymerase ii promoter GO:0045944 204 0.051
positive regulation of signaling GO:0023056 243 0.050
organelle fission GO:0048285 340 0.050
small molecule metabolic process GO:0044281 305 0.049
mitotic dna integrity checkpoint GO:0044774 75 0.049
positive regulation of cell communication GO:0010647 250 0.048
response to organophosphorus GO:0046683 2 0.046
immune response GO:0006955 246 0.045
establishment of protein localization GO:0045184 163 0.045
single organism cellular localization GO:1902580 180 0.045
cell cycle checkpoint GO:0000075 95 0.043
regulation of phosphorus metabolic process GO:0051174 210 0.043
positive regulation of nitrogen compound metabolic process GO:0051173 354 0.043
dna integrity checkpoint GO:0031570 81 0.041
regulation of mitotic cell cycle phase transition GO:1901990 130 0.041
appendage morphogenesis GO:0035107 397 0.040
positive regulation of biosynthetic process GO:0009891 316 0.040
negative regulation of cell cycle process GO:0010948 109 0.040
single organism catabolic process GO:0044712 228 0.039
single organism intracellular transport GO:1902582 207 0.038
organelle localization GO:0051640 148 0.038
ribonucleoside metabolic process GO:0009119 127 0.038
protein complex disassembly GO:0043241 36 0.037
negative regulation of signaling GO:0023057 219 0.037
secretion GO:0046903 109 0.037
establishment or maintenance of bipolar cell polarity GO:0061245 34 0.036
response to extracellular stimulus GO:0009991 116 0.035
response to organic substance GO:0010033 284 0.035
negative regulation of mitotic cell cycle phase transition GO:1901991 103 0.034
response to other organism GO:0051707 293 0.034
camera type eye development GO:0043010 4 0.034
mitotic g2 dna damage checkpoint GO:0007095 69 0.034
positive regulation of signal transduction GO:0009967 223 0.033
cellular catabolic process GO:0044248 372 0.033
positive regulation of cellular biosynthetic process GO:0031328 316 0.032
establishment of organelle localization GO:0051656 122 0.032
carbohydrate derivative biosynthetic process GO:1901137 85 0.032
purine containing compound metabolic process GO:0072521 155 0.031
regulation of cell cycle GO:0051726 291 0.031
positive regulation of response to stimulus GO:0048584 323 0.031
purine nucleoside metabolic process GO:0042278 127 0.031
positive regulation of rna metabolic process GO:0051254 271 0.031
vesicle mediated transport GO:0016192 381 0.031
phosphorylation GO:0016310 294 0.030
mitotic cell cycle phase transition GO:0044772 138 0.030
transcription from rna polymerase ii promoter GO:0006366 368 0.030
carbohydrate metabolic process GO:0005975 82 0.030
regulation of mitotic cell cycle GO:0007346 190 0.030
growth GO:0040007 359 0.030
positive regulation of gene expression GO:0010628 290 0.029
negative regulation of cellular metabolic process GO:0031324 382 0.029
negative regulation of mitotic cell cycle GO:0045930 109 0.029
regulation of cell cycle process GO:0010564 181 0.029
glycosyl compound metabolic process GO:1901657 127 0.028
rna processing GO:0006396 147 0.028
dna damage checkpoint GO:0000077 78 0.028
immune system process GO:0002376 347 0.028
ras protein signal transduction GO:0007265 88 0.028
regulation of immune response GO:0050776 118 0.027
ovarian follicle cell development GO:0030707 248 0.027
regulation of phosphate metabolic process GO:0019220 210 0.027
macromolecular complex assembly GO:0065003 256 0.027
regulation of cell cycle phase transition GO:1901987 130 0.027
developmental programmed cell death GO:0010623 138 0.027
purine ribonucleoside metabolic process GO:0046128 127 0.027
cellular macromolecular complex assembly GO:0034622 153 0.027
response to nutrient levels GO:0031667 114 0.027
single organism membrane organization GO:0044802 93 0.026
autophagy GO:0006914 108 0.026
positive regulation of phosphate metabolic process GO:0045937 139 0.026
tripartite regional subdivision GO:0007351 103 0.026
gland morphogenesis GO:0022612 145 0.025
notch signaling pathway GO:0007219 120 0.025
cell cycle phase transition GO:0044770 140 0.024
response to lipopolysaccharide GO:0032496 4 0.024
purine ribonucleotide metabolic process GO:0009150 145 0.024
organic substance catabolic process GO:1901575 308 0.024
regulation of mitosis GO:0007088 56 0.023
regulation of molecular function GO:0065009 217 0.023
regulation of intracellular signal transduction GO:1902531 236 0.023
mitotic dna damage checkpoint GO:0044773 74 0.023
nucleobase containing small molecule metabolic process GO:0055086 174 0.023
cellular response to dna damage stimulus GO:0006974 223 0.023
protein complex assembly GO:0006461 200 0.023
humoral immune response GO:0006959 117 0.023
mitotic nuclear division GO:0007067 213 0.022
regulation of small gtpase mediated signal transduction GO:0051056 93 0.022
oxoacid metabolic process GO:0043436 103 0.022
salivary gland development GO:0007431 162 0.022
organic substance transport GO:0071702 257 0.022
developmental maturation GO:0021700 172 0.022
columnar cuboidal epithelial cell differentiation GO:0002065 256 0.022
defense response GO:0006952 300 0.022
defense response to bacterium GO:0042742 178 0.022
negative regulation of biosynthetic process GO:0009890 277 0.021
purine nucleoside triphosphate metabolic process GO:0009144 119 0.021
golgi organization GO:0007030 66 0.021
regulation of catalytic activity GO:0050790 185 0.021
male gamete generation GO:0048232 201 0.021
dorsal ventral pattern formation GO:0009953 133 0.021
mitotic cell cycle embryonic GO:0045448 38 0.021
death GO:0016265 284 0.021
organelle assembly GO:0070925 198 0.020
neurological system process GO:0050877 358 0.020
spindle organization GO:0007051 253 0.020
secondary metabolic process GO:0019748 75 0.020
negative regulation of cell communication GO:0010648 223 0.020
negative regulation of cell cycle GO:0045786 116 0.020
positive regulation of nucleic acid templated transcription GO:1903508 266 0.020
eye development GO:0001654 323 0.020
embryonic axis specification GO:0000578 107 0.020
carboxylic acid metabolic process GO:0019752 92 0.020
autophagic cell death GO:0048102 83 0.020
gland development GO:0048732 191 0.020
kidney development GO:0001822 3 0.020
single organism biosynthetic process GO:0044711 206 0.020
protein localization to organelle GO:0033365 82 0.020
chromosome segregation GO:0007059 157 0.020
protein complex biogenesis GO:0070271 201 0.020
response to alcohol GO:0097305 95 0.020
protein targeting GO:0006605 64 0.020
organic acid metabolic process GO:0006082 103 0.020
negative regulation of signal transduction GO:0009968 206 0.020
axis specification GO:0009798 167 0.020
positive regulation of transcription dna templated GO:0045893 266 0.019
actin filament organization GO:0007015 126 0.019
regulation of cell shape GO:0008360 113 0.019
defense response to other organism GO:0098542 225 0.019
border follicle cell migration GO:0007298 113 0.019
intracellular transport GO:0046907 228 0.019
positive regulation of phosphorus metabolic process GO:0010562 139 0.019
blastoderm segmentation GO:0007350 159 0.019
nucleoside phosphate metabolic process GO:0006753 162 0.019
positive regulation of rna biosynthetic process GO:1902680 266 0.019
protein secretion GO:0009306 45 0.019
response to biotic stimulus GO:0009607 294 0.019
cellular protein localization GO:0034613 160 0.019
oocyte development GO:0048599 124 0.019
single organism behavior GO:0044708 391 0.019
nucleotide metabolic process GO:0009117 161 0.018
purine nucleotide metabolic process GO:0006163 146 0.018
response to sterol GO:0036314 34 0.018
dna templated transcription initiation GO:0006352 25 0.018
phagocytosis GO:0006909 215 0.018
intracellular signal transduction GO:0035556 300 0.018
positive regulation of intracellular signal transduction GO:1902533 116 0.018
retina development in camera type eye GO:0060041 4 0.018
regulation of cellular ketone metabolic process GO:0010565 3 0.018
mitotic spindle organization GO:0007052 220 0.018
membrane organization GO:0061024 112 0.018
cellular component disassembly GO:0022411 46 0.018
epithelial cell development GO:0002064 274 0.018
cell death GO:0008219 279 0.018
regulation of multi organism process GO:0043900 131 0.018
tissue death GO:0016271 102 0.018
developmental growth GO:0048589 280 0.018
ribonucleotide metabolic process GO:0009259 145 0.018
organic cyclic compound catabolic process GO:1901361 168 0.018
regulation of cellular component biogenesis GO:0044087 201 0.018
organonitrogen compound catabolic process GO:1901565 128 0.017
exocrine system development GO:0035272 162 0.017
ribonucleoside triphosphate catabolic process GO:0009203 108 0.017
lipid metabolic process GO:0006629 121 0.017
epithelial cell migration GO:0010631 148 0.017
regulation of notch signaling pathway GO:0008593 100 0.017
regulation of hydrolase activity GO:0051336 97 0.017
carbohydrate derivative catabolic process GO:1901136 118 0.017
digestive tract development GO:0048565 149 0.017
salivary gland histolysis GO:0035070 88 0.017
epithelium migration GO:0090132 148 0.017
negative regulation of cell cycle phase transition GO:1901988 103 0.017
negative regulation of cellular biosynthetic process GO:0031327 277 0.017
wing disc pattern formation GO:0035222 66 0.016
cellular nitrogen compound catabolic process GO:0044270 165 0.016
protein acylation GO:0043543 42 0.016
cellular response to nutrient levels GO:0031669 62 0.016
body morphogenesis GO:0010171 2 0.016
regulation of mrna splicing via spliceosome GO:0048024 64 0.016
regulation of cellular amine metabolic process GO:0033238 3 0.016
establishment of protein localization to organelle GO:0072594 62 0.016
tissue migration GO:0090130 155 0.016
regulation of cellular localization GO:0060341 136 0.016
mrna processing GO:0006397 104 0.016
regulation of mrna processing GO:0050684 71 0.016
negative regulation of nitrogen compound metabolic process GO:0051172 265 0.016
purine nucleotide catabolic process GO:0006195 109 0.016
taxis GO:0042330 304 0.016
nucleoside metabolic process GO:0009116 127 0.016
positive regulation of macromolecule biosynthetic process GO:0010557 283 0.016
regulation of microtubule based process GO:0032886 49 0.016
regulation of nucleotide metabolic process GO:0006140 62 0.016
columnar cuboidal epithelial cell development GO:0002066 249 0.016
ribonucleotide catabolic process GO:0009261 109 0.016
nucleotide catabolic process GO:0009166 109 0.016
cellular ketone metabolic process GO:0042180 24 0.015
anterior posterior axis specification embryo GO:0008595 103 0.015
anterior posterior axis specification GO:0009948 109 0.015
proteolysis GO:0006508 192 0.015
meiotic nuclear division GO:0007126 151 0.015
heterocycle catabolic process GO:0046700 166 0.015
embryonic morphogenesis GO:0048598 206 0.015
cytoplasmic transport GO:0016482 130 0.015
response to abiotic stimulus GO:0009628 341 0.015
compound eye morphogenesis GO:0001745 249 0.015
leg disc development GO:0035218 92 0.015
microtubule based transport GO:0010970 42 0.015
autophagic vacuole fusion GO:0000046 15 0.015
regulation of cytoskeleton organization GO:0051493 89 0.015
cell division GO:0051301 248 0.015
cellular carbohydrate metabolic process GO:0044262 22 0.015
cellular amino acid metabolic process GO:0006520 61 0.015
positive regulation of erk1 and erk2 cascade GO:0070374 36 0.015
inter male aggressive behavior GO:0002121 60 0.015
oocyte differentiation GO:0009994 145 0.015
ribonucleoside catabolic process GO:0042454 112 0.015
ribonucleoside triphosphate metabolic process GO:0009199 119 0.015
gtp catabolic process GO:0006184 72 0.015
antimicrobial humoral response GO:0019730 99 0.015
positive regulation of macromolecule metabolic process GO:0010604 405 0.015
cellular response to extracellular stimulus GO:0031668 64 0.015
cellular response to chemical stimulus GO:0070887 199 0.014
vesicle localization GO:0051648 55 0.014
organonitrogen compound biosynthetic process GO:1901566 117 0.014
compound eye development GO:0048749 307 0.014
negative regulation of notch signaling pathway GO:0045746 41 0.014
establishment or maintenance of epithelial cell apical basal polarity GO:0045197 24 0.014
salivary gland morphogenesis GO:0007435 145 0.014
signal transduction in response to dna damage GO:0042770 3 0.014
spermatogenesis GO:0007283 200 0.014
purine ribonucleoside triphosphate catabolic process GO:0009207 108 0.014
regulation of transcription from rna polymerase ii promoter GO:0006357 378 0.014
cellular lipid metabolic process GO:0044255 83 0.014
purine containing compound catabolic process GO:0072523 112 0.014
negative regulation of gene expression GO:0010629 387 0.014
connective tissue development GO:0061448 3 0.014
purine nucleoside catabolic process GO:0006152 112 0.014
nucleoside triphosphate catabolic process GO:0009143 108 0.014
response to starvation GO:0042594 97 0.014
salivary gland cell autophagic cell death GO:0035071 83 0.014
guanosine containing compound metabolic process GO:1901068 74 0.014
enzyme linked receptor protein signaling pathway GO:0007167 179 0.014
open tracheal system development GO:0007424 204 0.014
defense response to gram negative bacterium GO:0050829 94 0.014
regulation of localization GO:0032879 275 0.014
imaginal disc pattern formation GO:0007447 91 0.014
oligosaccharide metabolic process GO:0009311 18 0.014
ncrna metabolic process GO:0034660 43 0.014
homeostatic process GO:0042592 199 0.013
regulation of innate immune response GO:0045088 71 0.013
negative regulation of response to stimulus GO:0048585 258 0.013
vesicle organization GO:0016050 44 0.013
cellular response to molecule of bacterial origin GO:0071219 3 0.013
determination of adult lifespan GO:0008340 137 0.013
multicellular organismal aging GO:0010259 140 0.013
response to endogenous stimulus GO:0009719 119 0.013
cell fate determination GO:0001709 91 0.013
response to hexose GO:0009746 3 0.013
mitochondrion organization GO:0007005 65 0.013
negative regulation of macromolecule biosynthetic process GO:0010558 270 0.013
protein phosphorylation GO:0006468 169 0.013
ovarian follicle cell migration GO:0007297 121 0.013
pigmentation GO:0043473 75 0.013
regulation of erk1 and erk2 cascade GO:0070372 39 0.013
regulation of response to stress GO:0080134 200 0.013
response to oxygen containing compound GO:1901700 200 0.013
chromatin assembly GO:0031497 48 0.013
regulation of organelle organization GO:0033043 196 0.013
embryonic development via the syncytial blastoderm GO:0001700 148 0.013
purine nucleoside triphosphate catabolic process GO:0009146 108 0.013
organophosphate metabolic process GO:0019637 195 0.012
nucleoside phosphate catabolic process GO:1901292 110 0.012
rna splicing via transesterification reactions with bulged adenosine as nucleophile GO:0000377 73 0.012
spermatid differentiation GO:0048515 114 0.012
rna splicing via transesterification reactions GO:0000375 73 0.012
pigment metabolic process involved in pigmentation GO:0043474 33 0.012
cell cell signaling involved in cell fate commitment GO:0045168 210 0.012
cellular response to lipopolysaccharide GO:0071222 3 0.012
regulation of mrna metabolic process GO:1903311 72 0.012
male meiosis GO:0007140 52 0.012
regulation of ras protein signal transduction GO:0046578 93 0.012
endocytosis GO:0006897 310 0.012
negative regulation of rna metabolic process GO:0051253 251 0.012
locomotory behavior GO:0007626 176 0.012
secretion by cell GO:0032940 101 0.012
signal transduction by phosphorylation GO:0023014 107 0.012
peptide metabolic process GO:0006518 80 0.012
response to monosaccharide GO:0034284 4 0.012
cellular response to oxygen containing compound GO:1901701 79 0.012
regulation of rna splicing GO:0043484 69 0.012
guanosine containing compound catabolic process GO:1901069 74 0.012
purine ribonucleoside catabolic process GO:0046130 112 0.012
positive regulation of gtp catabolic process GO:0033126 43 0.012
response to bacterium GO:0009617 198 0.012
branching involved in open tracheal system development GO:0060446 45 0.012
positive regulation of phosphorylation GO:0042327 87 0.012
establishment or maintenance of apical basal cell polarity GO:0035088 34 0.012
segmentation GO:0035282 207 0.012
regulation of protein complex disassembly GO:0043244 29 0.012
regulation of phosphorylation GO:0042325 147 0.012
biological adhesion GO:0022610 138 0.011
internal peptidyl lysine acetylation GO:0018393 38 0.011
gene silencing by rna GO:0031047 57 0.011
positive regulation of catalytic activity GO:0043085 118 0.011
apoptotic process GO:0006915 159 0.011
dorsal closure GO:0007391 79 0.011
mapk cascade GO:0000165 107 0.011
macromolecular complex disassembly GO:0032984 37 0.011
immune response activating signal transduction GO:0002757 2 0.011
positive regulation of exocytosis GO:0045921 4 0.011
cell projection assembly GO:0030031 94 0.011
positive regulation of mapk cascade GO:0043410 63 0.011
oocyte dorsal ventral axis specification GO:0007310 34 0.011
dorsal ventral axis specification GO:0009950 66 0.011
regulation of cellular protein metabolic process GO:0032268 243 0.011
extrinsic apoptotic signaling pathway GO:0097191 1 0.011
negative regulation of cellular component organization GO:0051129 108 0.011
purine ribonucleotide catabolic process GO:0009154 109 0.011
positive regulation of cellular amine metabolic process GO:0033240 0 0.011
protein acetylation GO:0006473 39 0.011
forebrain development GO:0030900 2 0.011
regulation of embryonic development GO:0045995 68 0.011
dorsal appendage formation GO:0046843 47 0.011
regulation of defense response GO:0031347 102 0.011
lateral inhibition GO:0046331 206 0.011
organophosphate catabolic process GO:0046434 112 0.011
meiosis i GO:0007127 59 0.010
neuron projection guidance GO:0097485 241 0.010
regulation of anatomical structure morphogenesis GO:0022603 242 0.010
regulation of cell death GO:0010941 173 0.010
embryonic pattern specification GO:0009880 174 0.010
nucleoside triphosphate metabolic process GO:0009141 120 0.010
ameboidal type cell migration GO:0001667 151 0.010
developmental pigmentation GO:0048066 68 0.010
tissue morphogenesis GO:0048729 297 0.010
regulation of immune system process GO:0002682 176 0.010
cellular response to starvation GO:0009267 61 0.010
cellular response to organic substance GO:0071310 132 0.010
embryo development ending in birth or egg hatching GO:0009792 152 0.010
response to nitrogen compound GO:1901698 90 0.010
regulation of growth GO:0040008 233 0.010
rna 3 end processing GO:0031123 45 0.010
establishment or maintenance of cell polarity GO:0007163 167 0.010

Brf disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.032
nervous system disease DOID:863 0 0.014
disease of metabolism DOID:0014667 0 0.012