Drosophila melanogaster

86 known processes

Cenp-C (Dmel_CG31258)

CG31258 gene product from transcript CG31258-RA

(Aliases: CG11745,CG11746,Dmel\CG31258,l(3)85Aa,CENP-C,CLD1,L1,CG31258,Mmus\Numb[NPF.DPF.Scer\UAS])

Cenp-C biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
sister chromatid segregation GO:0000819 92 0.990
chromosome segregation GO:0007059 157 0.987
chromosome organization GO:0051276 360 0.981
mitotic sister chromatid segregation GO:0000070 87 0.975
meiotic cell cycle process GO:1903046 132 0.951
spindle organization GO:0007051 253 0.886
metaphase plate congression GO:0051310 19 0.885
organelle localization GO:0051640 148 0.845
meiotic nuclear division GO:0007126 151 0.840
mitotic sister chromatid separation GO:0051306 30 0.833
dna metabolic process GO:0006259 227 0.759
meiotic cell cycle GO:0051321 171 0.711
mitotic metaphase plate congression GO:0007080 13 0.593
mitotic spindle stabilization GO:0043148 6 0.579
nuclear division GO:0000280 332 0.568
organelle fission GO:0048285 340 0.565
meiotic spindle organization GO:0000212 36 0.539
organelle assembly GO:0070925 198 0.517
mitotic spindle organization GO:0007052 220 0.513
establishment of organelle localization GO:0051656 122 0.488
meiotic chromosome segregation GO:0045132 59 0.481
chromosome condensation GO:0030261 41 0.434
dna conformation change GO:0071103 105 0.417
female meiosis chromosome segregation GO:0016321 33 0.403
regulation of microtubule based process GO:0032886 49 0.401
protein dna complex subunit organization GO:0071824 86 0.362
regulation of cell cycle phase transition GO:1901987 130 0.323
regulation of microtubule cytoskeleton organization GO:0070507 41 0.318
regulation of mitotic sister chromatid separation GO:0010965 28 0.305
spindle midzone assembly GO:0051255 4 0.297
cell cycle phase transition GO:0044770 140 0.295
mitotic nuclear division GO:0007067 213 0.289
mitotic chromosome condensation GO:0007076 22 0.286
centrosome cycle GO:0007098 137 0.285
spindle assembly involved in mitosis GO:0090307 50 0.254
regulation of mitotic spindle organization GO:0060236 9 0.243
chromosome localization GO:0050000 20 0.242
positive regulation of metaphase anaphase transition of cell cycle GO:1902101 10 0.240
chromosome movement towards spindle pole GO:0051305 4 0.219
telomere organization GO:0032200 21 0.209
positive regulation of mitotic sister chromatid separation GO:1901970 10 0.205
regulation of proteasomal protein catabolic process GO:0061136 39 0.185
negative regulation of mitotic cell cycle phase transition GO:1901991 103 0.184
regulation of mitotic sister chromatid segregation GO:0033047 28 0.183
photoreceptor cell differentiation GO:0046530 170 0.176
dna damage checkpoint GO:0000077 78 0.158
nuclear migration GO:0007097 20 0.156
female meiotic division GO:0007143 70 0.155
spindle assembly GO:0051225 80 0.151
eye photoreceptor cell differentiation GO:0001754 145 0.151
regulation of chromosome organization GO:0033044 64 0.151
cellular macromolecular complex assembly GO:0034622 153 0.149
chromosome separation GO:0051304 42 0.148
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 54 0.142
catabolic process GO:0009056 409 0.135
regulation of cellular catabolic process GO:0031329 157 0.133
cell division GO:0051301 248 0.123
dna packaging GO:0006323 91 0.120
maintenance of protein location in cell GO:0032507 26 0.118
metaphase anaphase transition of mitotic cell cycle GO:0007091 28 0.114
centrosome duplication GO:0051298 121 0.112
cell cycle checkpoint GO:0000075 95 0.106
regulation of cell division GO:0051302 72 0.105
regulation of mitotic cell cycle phase transition GO:1901990 130 0.104
establishment of chromosome localization GO:0051303 20 0.103
modification dependent protein catabolic process GO:0019941 78 0.101
microtubule based movement GO:0007018 51 0.101
cellular protein catabolic process GO:0044257 83 0.100
positive regulation of mitotic metaphase anaphase transition GO:0045842 10 0.098
spindle assembly involved in meiosis GO:0090306 20 0.097
cellular catabolic process GO:0044248 372 0.096
protein dna complex assembly GO:0065004 63 0.094
nucleosome organization GO:0034728 59 0.093
wnt signaling pathway GO:0016055 98 0.091
ubiquitin dependent protein catabolic process GO:0006511 78 0.091
regulation of proteasomal ubiquitin dependent protein catabolic process GO:0032434 37 0.090
kinetochore organization GO:0051383 9 0.089
microtubule depolymerization GO:0007019 25 0.088
negative regulation of organelle organization GO:0010639 56 0.087
cellular protein complex disassembly GO:0043624 35 0.085
proteolysis involved in cellular protein catabolic process GO:0051603 83 0.077
protein complex biogenesis GO:0070271 201 0.075
regulation of metaphase anaphase transition of cell cycle GO:1902099 26 0.073
maintenance of protein location GO:0045185 28 0.073
axon development GO:0061564 297 0.071
mitotic spindle midzone assembly GO:0051256 1 0.068
cytoskeleton dependent cytokinesis GO:0061640 81 0.066
heterocycle catabolic process GO:0046700 166 0.066
transcription from rna polymerase ii promoter GO:0006366 368 0.065
negative regulation of protein depolymerization GO:1901880 23 0.065
centrosome organization GO:0051297 163 0.064
regulation of protein complex disassembly GO:0043244 29 0.063
meiotic sister chromatid segregation GO:0045144 6 0.061
regulation of wnt signaling pathway GO:0030111 68 0.060
regulation of mitotic cell cycle GO:0007346 190 0.060
axonogenesis GO:0007409 290 0.058
maintenance of location GO:0051235 73 0.058
centromere complex assembly GO:0034508 7 0.058
dendrite development GO:0016358 204 0.058
establishment or maintenance of cell polarity GO:0007163 167 0.057
body morphogenesis GO:0010171 2 0.057
modification dependent macromolecule catabolic process GO:0043632 79 0.055
positive regulation of proteasomal protein catabolic process GO:1901800 20 0.055
regulation of mitotic metaphase anaphase transition GO:0030071 26 0.054
muscle structure development GO:0061061 224 0.054
cell death GO:0008219 279 0.053
lateral inhibition GO:0046331 206 0.051
metaphase anaphase transition of cell cycle GO:0044784 28 0.050
regulation of gene silencing GO:0060968 63 0.049
negative regulation of microtubule polymerization or depolymerization GO:0031111 21 0.049
regulation of cellular protein catabolic process GO:1903362 44 0.049
spindle assembly involved in female meiosis i GO:0007057 5 0.049
cellular protein complex assembly GO:0043623 71 0.048
appendage development GO:0048736 401 0.047
germarium derived female germ line cyst formation GO:0030727 42 0.047
positive regulation of nucleobase containing compound metabolic process GO:0045935 332 0.047
regulation of proteolysis involved in cellular protein catabolic process GO:1903050 44 0.047
aromatic compound catabolic process GO:0019439 166 0.047
mitotic cell cycle phase transition GO:0044772 138 0.046
spindle assembly involved in female meiosis GO:0007056 14 0.046
cellular macromolecule catabolic process GO:0044265 136 0.045
eye photoreceptor cell development GO:0042462 81 0.044
regulation of catabolic process GO:0009894 170 0.044
macromolecular complex assembly GO:0065003 256 0.044
single organism catabolic process GO:0044712 228 0.042
establishment of localization in cell GO:0051649 402 0.042
vesicle mediated transport GO:0016192 381 0.041
regulation of meiosis GO:0040020 3 0.041
positive regulation of nucleic acid templated transcription GO:1903508 266 0.040
negative regulation of cell cycle GO:0045786 116 0.039
organic substance catabolic process GO:1901575 308 0.039
macromolecule catabolic process GO:0009057 161 0.038
mitotic dna damage checkpoint GO:0044773 74 0.037
negative regulation of microtubule depolymerization GO:0007026 21 0.037
negative regulation of protein complex disassembly GO:0043242 23 0.036
positive regulation of protein complex assembly GO:0031334 22 0.036
dendrite morphogenesis GO:0048813 199 0.036
positive regulation of macromolecule metabolic process GO:0010604 405 0.036
positive regulation of proteolysis involved in cellular protein catabolic process GO:1903052 24 0.036
telomere maintenance GO:0000723 21 0.036
programmed cell death GO:0012501 257 0.035
atp metabolic process GO:0046034 49 0.035
regulation of protein catabolic process GO:0042176 55 0.035
positive regulation of proteasomal ubiquitin dependent protein catabolic process GO:0032436 19 0.035
sensory organ morphogenesis GO:0090596 260 0.035
embryonic morphogenesis GO:0048598 206 0.034
phagocytosis GO:0006909 215 0.034
purine ribonucleoside monophosphate catabolic process GO:0009169 38 0.034
pronuclear migration GO:0035046 4 0.034
negative regulation of cell cycle process GO:0010948 109 0.033
negative regulation of cytoskeleton organization GO:0051494 30 0.033
microtubule cytoskeleton organization involved in mitosis GO:1902850 52 0.033
photoreceptor cell development GO:0042461 96 0.032
organic cyclic compound catabolic process GO:1901361 168 0.032
meiotic spindle midzone assembly GO:0051257 3 0.032
establishment of nucleus localization GO:0040023 26 0.032
gliogenesis GO:0042063 80 0.032
dna integrity checkpoint GO:0031570 81 0.031
regulation of cell cycle GO:0051726 291 0.031
imaginal disc derived appendage morphogenesis GO:0035114 395 0.031
glial cell differentiation GO:0010001 35 0.031
mitotic cell cycle checkpoint GO:0007093 88 0.031
regulation of neuron projection development GO:0010975 69 0.031
dna replication GO:0006260 48 0.030
protein localization GO:0008104 284 0.030
synaptonemal complex organization GO:0070193 5 0.029
chromatin remodeling GO:0006338 72 0.029
chromatin modification GO:0016568 147 0.029
protein complex disassembly GO:0043241 36 0.029
positive regulation of protein catabolic process GO:0045732 34 0.029
positive regulation of nitrogen compound metabolic process GO:0051173 354 0.029
embryo development ending in birth or egg hatching GO:0009792 152 0.029
protein depolymerization GO:0051261 31 0.028
regulation of microtubule polymerization or depolymerization GO:0031110 27 0.028
cell cell signaling involved in cell fate commitment GO:0045168 210 0.028
regulation of mitotic spindle elongation GO:0032888 1 0.027
regulation of chromosome segregation GO:0051983 32 0.027
embryonic cleavage GO:0040016 5 0.027
mitotic dna integrity checkpoint GO:0044774 75 0.027
regulation of sister chromatid segregation GO:0033045 28 0.027
compound eye photoreceptor cell differentiation GO:0001751 140 0.026
regulation of organelle organization GO:0033043 196 0.026
neuroblast differentiation GO:0014016 29 0.026
negative regulation of cell cycle g2 m phase transition GO:1902750 8 0.026
positive regulation of transcription factor import into nucleus GO:0042993 19 0.025
neuron projection guidance GO:0097485 241 0.025
positive regulation of rna biosynthetic process GO:1902680 266 0.025
digestive tract development GO:0048565 149 0.024
chromatin assembly or disassembly GO:0006333 52 0.024
positive regulation of mitotic cell cycle GO:0045931 34 0.023
negative regulation of meiotic cell cycle GO:0051447 2 0.023
cytokinesis GO:0000910 90 0.023
death GO:0016265 284 0.023
nucleosome assembly GO:0006334 35 0.023
compound eye photoreceptor development GO:0042051 78 0.023
meiotic sister chromatid cohesion GO:0051177 6 0.023
glial cell development GO:0021782 27 0.022
cellular response to dna damage stimulus GO:0006974 223 0.022
microtubule organizing center organization GO:0031023 168 0.022
nucleoside phosphate catabolic process GO:1901292 110 0.022
positive regulation of macromolecule biosynthetic process GO:0010557 283 0.022
regulation of microtubule depolymerization GO:0031114 24 0.021
positive regulation of cellular biosynthetic process GO:0031328 316 0.021
apoptotic process GO:0006915 159 0.021
regulation of nuclear division GO:0051783 58 0.021
microtubule anchoring GO:0034453 11 0.021
attachment of spindle microtubules to kinetochore GO:0008608 5 0.021
regulation of neuron differentiation GO:0045664 103 0.021
establishment or maintenance of apical basal cell polarity GO:0035088 34 0.021
positive regulation of rna metabolic process GO:0051254 271 0.021
purine ribonucleoside catabolic process GO:0046130 112 0.021
nucleus localization GO:0051647 34 0.021
anatomical structure homeostasis GO:0060249 97 0.021
compound eye development GO:0048749 307 0.020
meiotic cytokinesis GO:0033206 33 0.020
regulation of centrosome cycle GO:0046605 7 0.020
response to other organism GO:0051707 293 0.020
single organism membrane organization GO:0044802 93 0.020
regulation of cellular component biogenesis GO:0044087 201 0.020
cuticle development GO:0042335 86 0.020
ribonucleoside metabolic process GO:0009119 127 0.019
spindle stabilization GO:0043146 14 0.019
maintenance of location in cell GO:0051651 28 0.019
glial cell fate determination GO:0007403 3 0.019
organonitrogen compound metabolic process GO:1901564 318 0.019
regulation of protein depolymerization GO:1901879 27 0.019
eye development GO:0001654 323 0.019
endocytosis GO:0006897 310 0.019
positive regulation of catabolic process GO:0009896 105 0.019
positive regulation of cellular catabolic process GO:0031331 95 0.018
cellular protein localization GO:0034613 160 0.018
double strand break repair via synthesis dependent strand annealing GO:0045003 6 0.018
limb morphogenesis GO:0035108 1 0.018
telencephalon development GO:0021537 2 0.018
pronuclear fusion GO:0007344 4 0.018
regulation of spindle organization GO:0090224 17 0.017
mitotic spindle elongation GO:0000022 81 0.017
positive regulation of cellular component organization GO:0051130 156 0.017
glycosyl compound catabolic process GO:1901658 112 0.017
imaginal disc derived wing vein specification GO:0007474 48 0.017
tube development GO:0035295 244 0.017
regulation of cytoskeleton organization GO:0051493 89 0.017
mrna splice site selection GO:0006376 1 0.017
cellular component assembly involved in morphogenesis GO:0010927 151 0.016
nucleotide catabolic process GO:0009166 109 0.016
protein polymerization GO:0051258 42 0.016
neuron recognition GO:0008038 101 0.016
limb development GO:0060173 1 0.016
imaginal disc derived wing morphogenesis GO:0007476 337 0.016
gland morphogenesis GO:0022612 145 0.016
positive regulation of cellular component biogenesis GO:0044089 80 0.016
ectodermal digestive tract morphogenesis GO:0048567 7 0.016
positive regulation of chromosome segregation GO:0051984 10 0.016
female meiosis i GO:0007144 8 0.016
chromatin organization GO:0006325 207 0.015
macromolecular complex disassembly GO:0032984 37 0.015
negative regulation of protein metabolic process GO:0051248 85 0.015
axonal fasciculation GO:0007413 12 0.015
somatic muscle development GO:0007525 66 0.015
mitotic cytokinesis GO:0000281 50 0.015
genitalia development GO:0048806 26 0.015
negative regulation of cellular metabolic process GO:0031324 382 0.015
positive regulation of r7 cell differentiation GO:0045678 7 0.015
forebrain development GO:0030900 2 0.015
autophagic cell death GO:0048102 83 0.015
negative regulation of neuroblast proliferation GO:0007406 27 0.015
tissue morphogenesis GO:0048729 297 0.014
organonitrogen compound catabolic process GO:1901565 128 0.014
cellular nitrogen compound catabolic process GO:0044270 165 0.014
mitotic spindle assembly checkpoint GO:0007094 11 0.014
establishment of spindle orientation GO:0051294 18 0.014
regulation of dendrite development GO:0050773 37 0.014
ribonucleoside monophosphate metabolic process GO:0009161 51 0.014
proteasomal protein catabolic process GO:0010498 59 0.014
chemosensory behavior GO:0007635 106 0.014
regulation of hemocyte proliferation GO:0035206 37 0.014
cytoplasmic transport GO:0016482 130 0.014
purine ribonucleotide metabolic process GO:0009150 145 0.014
nucleoside triphosphate catabolic process GO:0009143 108 0.014
neuroblast development GO:0014019 13 0.014
nucleoside metabolic process GO:0009116 127 0.013
regulation of cyclin dependent protein serine threonine kinase activity GO:0000079 3 0.013
germarium derived egg chamber formation GO:0007293 101 0.013
embryonic development via the syncytial blastoderm GO:0001700 148 0.013
ribonucleotide catabolic process GO:0009261 109 0.013
mitotic centrosome separation GO:0007100 8 0.013
response to abiotic stimulus GO:0009628 341 0.013
anaphase promoting complex dependent proteasomal ubiquitin dependent protein catabolic process GO:0031145 30 0.013
telomere capping GO:0016233 11 0.013
atp dependent chromatin remodeling GO:0043044 22 0.013
peptidyl threonine phosphorylation GO:0018107 2 0.013
purine ribonucleotide catabolic process GO:0009154 109 0.013
spindle elongation GO:0051231 83 0.013
ribonucleoside catabolic process GO:0042454 112 0.013
organophosphate metabolic process GO:0019637 195 0.013
regulation of chromatin assembly GO:0010847 9 0.013
response to organonitrogen compound GO:0010243 75 0.013
g2 dna damage checkpoint GO:0031572 69 0.013
nephron epithelium development GO:0072009 3 0.013
histone h4 k20 methylation GO:0034770 4 0.013
epithelial cell development GO:0002064 274 0.012
cell proliferation GO:0008283 299 0.012
head involution GO:0008258 35 0.012
positive regulation of biosynthetic process GO:0009891 316 0.012
regulation of neuroblast proliferation GO:1902692 34 0.012
small molecule metabolic process GO:0044281 305 0.012
neuron remodeling GO:0016322 29 0.012
dorsal appendage formation GO:0046843 47 0.012
purine nucleoside triphosphate metabolic process GO:0009144 119 0.012
nucleobase containing compound catabolic process GO:0034655 165 0.012
cellular macromolecule localization GO:0070727 220 0.012
recombinational repair GO:0000725 13 0.012
mitotic sister chromatid cohesion GO:0007064 6 0.012
female germ line cyst formation GO:0048135 42 0.011
single organism biosynthetic process GO:0044711 206 0.011
negative regulation of mitotic sister chromatid separation GO:2000816 13 0.011
negative regulation of neurogenesis GO:0050768 53 0.011
chromosome organization involved in meiosis GO:0070192 10 0.011
imaginal disc derived appendage development GO:0048737 399 0.011
purine ribonucleoside triphosphate catabolic process GO:0009207 108 0.011
growth GO:0040007 359 0.011
positive regulation of protein metabolic process GO:0051247 128 0.011
salivary gland cell autophagic cell death GO:0035071 83 0.011
membrane organization GO:0061024 112 0.011
positive regulation of transcription dna templated GO:0045893 266 0.011
eye morphogenesis GO:0048592 260 0.011
eggshell chorion assembly GO:0007306 66 0.011
morphogenesis of an epithelium GO:0002009 276 0.011
negative regulation of mitotic cell cycle GO:0045930 109 0.011
protein transport GO:0015031 155 0.011
positive regulation of protein polymerization GO:0032273 14 0.010
regulation of glial cell differentiation GO:0045685 1 0.010
adult behavior GO:0030534 137 0.010
appendage morphogenesis GO:0035107 397 0.010
regulation of dna metabolic process GO:0051052 34 0.010
male meiosis GO:0007140 52 0.010
neuroblast fate commitment GO:0014017 19 0.010
ribose phosphate metabolic process GO:0019693 145 0.010
nucleolus organization GO:0007000 4 0.010
photoreceptor cell fate commitment GO:0046552 41 0.010
embryonic organ development GO:0048568 50 0.010
neuron fate commitment GO:0048663 50 0.010
axon guidance GO:0007411 233 0.010
negative regulation of protein catabolic process GO:0042177 17 0.010

Cenp-C disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.029