Drosophila melanogaster

8 known processes

Ppn (Dmel_CG33103)

Papilin

(Aliases: CG33103,CG18436,Dmel\CG33103,ppn,ppl,CG1540,CT3186,CT41988)

Ppn biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
muscle structure development GO:0061061 224 0.832
striated muscle cell differentiation GO:0051146 90 0.813
organic substance transport GO:0071702 257 0.509
malpighian tubule morphogenesis GO:0007443 44 0.493
regulation of multicellular organismal development GO:2000026 414 0.489
response to abiotic stimulus GO:0009628 341 0.446
skeletal muscle organ development GO:0060538 48 0.405
morphogenesis of an epithelium GO:0002009 276 0.335
axon development GO:0061564 297 0.320
muscle cell differentiation GO:0042692 103 0.265
extracellular structure organization GO:0043062 46 0.231
malpighian tubule development GO:0072002 64 0.228
open tracheal system development GO:0007424 204 0.221
muscle organ development GO:0007517 127 0.201
male mating behavior GO:0060179 70 0.179
body morphogenesis GO:0010171 2 0.178
nephron development GO:0072006 3 0.166
muscle attachment GO:0016203 36 0.165
regulation of nervous system development GO:0051960 248 0.159
positive regulation of developmental process GO:0051094 143 0.157
regulation of localization GO:0032879 275 0.156
heart development GO:0007507 82 0.155
renal system development GO:0072001 72 0.153
hindgut morphogenesis GO:0007442 58 0.150
response to biotic stimulus GO:0009607 294 0.147
striated muscle cell development GO:0055002 50 0.143
tissue morphogenesis GO:0048729 297 0.142
respiratory system development GO:0060541 213 0.134
muscle tissue development GO:0060537 30 0.129
basement membrane organization GO:0071711 10 0.126
renal tubule development GO:0061326 64 0.125
growth GO:0040007 359 0.124
actin cytoskeleton organization GO:0030036 206 0.119
chemotaxis GO:0006935 249 0.116
head development GO:0060322 135 0.116
branching morphogenesis of an epithelial tube GO:0048754 45 0.116
gliogenesis GO:0042063 80 0.112
response to decreased oxygen levels GO:0036293 58 0.112
regulation of neurogenesis GO:0050767 158 0.110
negative regulation of biosynthetic process GO:0009890 277 0.109
response to other organism GO:0051707 293 0.108
establishment of protein localization GO:0045184 163 0.108
defense response to bacterium GO:0042742 178 0.106
cellular response to organic substance GO:0071310 132 0.105
trachea development GO:0060438 29 0.103
urogenital system development GO:0001655 72 0.102
response to nitrogen compound GO:1901698 90 0.101
tube development GO:0035295 244 0.095
ion transmembrane transport GO:0034220 122 0.092
immune response GO:0006955 246 0.091
single organism behavior GO:0044708 391 0.089
epithelial tube morphogenesis GO:0060562 88 0.089
homeostatic process GO:0042592 199 0.088
renal tubule morphogenesis GO:0061333 44 0.086
regulation of cellular component biogenesis GO:0044087 201 0.085
axon guidance GO:0007411 233 0.084
morphogenesis of a branching structure GO:0001763 45 0.084
protein localization GO:0008104 284 0.082
negative regulation of multicellular organismal process GO:0051241 142 0.081
gland development GO:0048732 191 0.079
forebrain development GO:0030900 2 0.075
camera type eye development GO:0043010 4 0.075
kidney epithelium development GO:0072073 3 0.074
tube morphogenesis GO:0035239 191 0.074
small molecule metabolic process GO:0044281 305 0.073
cellular response to endogenous stimulus GO:0071495 80 0.072
negative regulation of cellular macromolecule biosynthetic process GO:2000113 267 0.072
cardiocyte differentiation GO:0035051 29 0.072
cell cell junction assembly GO:0007043 38 0.067
cellular response to chemical stimulus GO:0070887 199 0.066
tissue migration GO:0090130 155 0.066
negative regulation of cellular biosynthetic process GO:0031327 277 0.066
neuron projection guidance GO:0097485 241 0.065
response to organonitrogen compound GO:0010243 75 0.065
cellular catabolic process GO:0044248 372 0.065
brain development GO:0007420 120 0.064
striated muscle tissue development GO:0014706 27 0.063
cellular amino acid metabolic process GO:0006520 61 0.062
skeletal muscle tissue development GO:0007519 13 0.062
kidney development GO:0001822 3 0.061
lipid metabolic process GO:0006629 121 0.061
digestive tract development GO:0048565 149 0.058
morphogenesis of a branching epithelium GO:0061138 45 0.058
response to oxygen containing compound GO:1901700 200 0.057
single organism catabolic process GO:0044712 228 0.057
regulation of epithelial cell proliferation GO:0050678 4 0.057
cellular response to amino acid stimulus GO:0071230 6 0.056
intracellular signal transduction GO:0035556 300 0.056
detection of visible light GO:0009584 38 0.056
taxis GO:0042330 304 0.056
stem cell differentiation GO:0048863 117 0.055
positive regulation of nervous system development GO:0051962 69 0.054
branching involved in open tracheal system development GO:0060446 45 0.054
central nervous system development GO:0007417 201 0.054
protein modification process GO:0036211 438 0.054
courtship behavior GO:0007619 68 0.053
ethanolamine containing compound metabolic process GO:0042439 4 0.053
embryonic hindgut morphogenesis GO:0048619 48 0.053
imaginal disc derived appendage morphogenesis GO:0035114 395 0.053
regulation of developmental growth GO:0048638 174 0.052
response to hypoxia GO:0001666 53 0.051
single organism cellular localization GO:1902580 180 0.051
male courtship behavior veined wing extension GO:0048065 22 0.051
humoral immune response GO:0006959 117 0.050
syncytium formation GO:0006949 43 0.050
regulation of neuron differentiation GO:0045664 103 0.049
axonogenesis GO:0007409 290 0.049
endocytosis GO:0006897 310 0.049
defense response GO:0006952 300 0.048
anterior malpighian tubule development GO:0061327 12 0.048
nuclear division GO:0000280 332 0.048
endomembrane system organization GO:0010256 119 0.047
response to bacterium GO:0009617 198 0.047
secretion by cell GO:0032940 101 0.047
positive regulation of cell development GO:0010720 61 0.046
regulation of cell differentiation GO:0045595 302 0.046
ribonucleoside catabolic process GO:0042454 112 0.046
negative regulation of nitrogen compound metabolic process GO:0051172 265 0.045
regulation of transport GO:0051049 181 0.045
imaginal disc derived wing morphogenesis GO:0007476 337 0.044
protein transport GO:0015031 155 0.044
retina development in camera type eye GO:0060041 4 0.043
response to endogenous stimulus GO:0009719 119 0.043
regulation of secretion GO:0051046 44 0.043
single organism biosynthetic process GO:0044711 206 0.043
immune system process GO:0002376 347 0.042
eye development GO:0001654 323 0.042
cellular macromolecule localization GO:0070727 220 0.041
regulation of cell development GO:0060284 215 0.040
organ growth GO:0035265 56 0.040
response to light stimulus GO:0009416 124 0.040
purine ribonucleotide catabolic process GO:0009154 109 0.039
intracellular protein transport GO:0006886 104 0.039
cellular amine metabolic process GO:0044106 12 0.039
circulatory system development GO:0072359 82 0.038
vesicle mediated transport GO:0016192 381 0.038
learning GO:0007612 75 0.038
appendage development GO:0048736 401 0.038
chemical homeostasis GO:0048878 92 0.038
positive regulation of cell differentiation GO:0045597 64 0.038
eye morphogenesis GO:0048592 260 0.038
trachea morphogenesis GO:0060439 22 0.037
regulation of membrane potential GO:0042391 35 0.037
single organismal cell cell adhesion GO:0016337 45 0.036
ribonucleotide metabolic process GO:0009259 145 0.036
cellular response to organonitrogen compound GO:0071417 36 0.036
nucleobase containing compound catabolic process GO:0034655 165 0.036
larval development GO:0002164 104 0.036
cardiovascular system development GO:0072358 82 0.035
negative regulation of developmental process GO:0051093 201 0.035
action potential GO:0001508 13 0.035
skeletal muscle fiber development GO:0048741 3 0.035
neuronal action potential GO:0019228 10 0.035
regulation of protein localization GO:0032880 76 0.035
syncytium formation by plasma membrane fusion GO:0000768 43 0.034
nucleotide catabolic process GO:0009166 109 0.034
hindgut development GO:0061525 58 0.033
cellular protein modification process GO:0006464 438 0.032
organophosphate catabolic process GO:0046434 112 0.032
regeneration GO:0031099 16 0.032
cellular homeostasis GO:0019725 80 0.032
mitotic nuclear division GO:0007067 213 0.032
oxoacid metabolic process GO:0043436 103 0.032
carboxylic acid metabolic process GO:0019752 92 0.032
positive regulation of developmental growth GO:0048639 62 0.032
stem cell development GO:0048864 79 0.032
apical junction assembly GO:0043297 32 0.032
cell division GO:0051301 248 0.032
embryo development ending in birth or egg hatching GO:0009792 152 0.031
epithelial cell proliferation involved in renal tubule morphogenesis GO:2001013 11 0.031
response to oxygen levels GO:0070482 59 0.031
neuron recognition GO:0008038 101 0.031
glial cell differentiation GO:0010001 35 0.030
neuromuscular junction development GO:0007528 149 0.030
regulation of protein transport GO:0051223 57 0.030
pigmentation GO:0043473 75 0.030
connective tissue development GO:0061448 3 0.030
glial cell development GO:0021782 27 0.029
developmental growth GO:0048589 280 0.029
cell motility GO:0048870 251 0.029
regulation of cell projection organization GO:0031344 92 0.028
negative regulation of cellular metabolic process GO:0031324 382 0.028
cellular response to oxygen containing compound GO:1901701 79 0.028
stem cell division GO:0017145 69 0.028
post embryonic appendage morphogenesis GO:0035120 385 0.028
cuticle development GO:0042335 86 0.028
response to lipopolysaccharide GO:0032496 4 0.028
cell proliferation GO:0008283 299 0.027
purine ribonucleoside triphosphate metabolic process GO:0009205 119 0.027
imaginal disc derived appendage development GO:0048737 399 0.027
extrinsic apoptotic signaling pathway GO:0097191 1 0.027
actin filament based process GO:0030029 220 0.027
purine nucleoside metabolic process GO:0042278 127 0.027
larval somatic muscle development GO:0007526 19 0.027
regulation of cellular localization GO:0060341 136 0.026
cellular response to nitrogen compound GO:1901699 51 0.026
purine ribonucleoside metabolic process GO:0046128 127 0.026
synapse organization GO:0050808 196 0.026
regulation of notch signaling pathway GO:0008593 100 0.026
dna conformation change GO:0071103 105 0.026
catabolic process GO:0009056 409 0.026
regulation of sequestering of triglyceride GO:0010889 3 0.026
glycosyl compound catabolic process GO:1901658 112 0.026
heart contraction GO:0060047 26 0.026
negative regulation of cell differentiation GO:0045596 143 0.025
negative regulation of rna metabolic process GO:0051253 251 0.025
response to acid chemical GO:0001101 25 0.025
cardiac muscle tissue development GO:0048738 9 0.025
cell cell junction organization GO:0045216 55 0.025
stem cell maintenance GO:0019827 67 0.024
defense response to other organism GO:0098542 225 0.024
positive regulation of immune system process GO:0002684 68 0.024
heart process GO:0003015 37 0.024
actin filament organization GO:0007015 126 0.024
digestive system development GO:0055123 149 0.024
signal transduction by phosphorylation GO:0023014 107 0.024
positive regulation of defense response GO:0031349 59 0.023
lipid biosynthetic process GO:0008610 46 0.023
positive regulation of multicellular organismal process GO:0051240 143 0.023
embryonic axis specification GO:0000578 107 0.023
carbohydrate derivative metabolic process GO:1901135 217 0.023
positive regulation of protein secretion GO:0050714 9 0.023
cell migration GO:0016477 238 0.022
compound eye morphogenesis GO:0001745 249 0.022
ribonucleoside triphosphate catabolic process GO:0009203 108 0.022
regulation of protein secretion GO:0050708 13 0.022
salivary gland development GO:0007431 162 0.022
optokinetic behavior GO:0007634 3 0.022
embryonic morphogenesis GO:0048598 206 0.022
response to amino acid GO:0043200 6 0.021
aging GO:0007568 143 0.021
protein import GO:0017038 55 0.021
organonitrogen compound metabolic process GO:1901564 318 0.021
digestive tract morphogenesis GO:0048546 127 0.021
glycoprotein metabolic process GO:0009100 41 0.021
establishment of localization in cell GO:0051649 402 0.021
detection of light stimulus GO:0009583 58 0.021
single organism cell adhesion GO:0098602 47 0.021
regulation of cell proliferation GO:0042127 163 0.021
sterol homeostasis GO:0055092 4 0.020
response to organic cyclic compound GO:0014070 89 0.020
organic substance catabolic process GO:1901575 308 0.020
localization of cell GO:0051674 257 0.020
glial cell migration GO:0008347 31 0.020
positive regulation of neurogenesis GO:0050769 41 0.020
cellular response to growth factor stimulus GO:0071363 30 0.020
organic cyclic compound catabolic process GO:1901361 168 0.020
extracellular matrix organization GO:0030198 32 0.020
response to radiation GO:0009314 155 0.020
positive regulation of cellular amino acid metabolic process GO:0045764 0 0.020
endodermal cell differentiation GO:0035987 3 0.019
negative regulation of macromolecule biosynthetic process GO:0010558 270 0.019
response to external biotic stimulus GO:0043207 293 0.019
negative regulation of cellular component organization GO:0051129 108 0.019
maintenance of location GO:0051235 73 0.019
detection of stimulus involved in sensory perception GO:0050906 92 0.019
myofibril assembly GO:0030239 36 0.019
heterocycle catabolic process GO:0046700 166 0.019
branch fusion open tracheal system GO:0035147 17 0.019
transmembrane transport GO:0055085 139 0.019
imaginal disc derived wing margin morphogenesis GO:0008587 41 0.019
muscle cell development GO:0055001 50 0.019
positive regulation of cellular biosynthetic process GO:0031328 316 0.019
lipid storage GO:0019915 38 0.019
cellular ketone metabolic process GO:0042180 24 0.018
response to hormone GO:0009725 45 0.018
lipid localization GO:0010876 54 0.018
positive regulation of protein transport GO:0051222 37 0.018
enzyme linked receptor protein signaling pathway GO:0007167 179 0.018
multicellular organismal signaling GO:0035637 12 0.018
extracellular matrix disassembly GO:0022617 4 0.018
cell recognition GO:0008037 102 0.018
regulation of ion transmembrane transport GO:0034765 27 0.018
cell adhesion mediated by integrin GO:0033627 12 0.018
translation GO:0006412 69 0.018
cellular macromolecular complex assembly GO:0034622 153 0.018
regulation of immune system process GO:0002682 176 0.018
mesenchymal cell differentiation GO:0048762 1 0.018
embryonic pattern specification GO:0009880 174 0.018
cellular response to external stimulus GO:0071496 66 0.018
negative regulation of epithelial cell proliferation GO:0050680 4 0.018
purine ribonucleoside catabolic process GO:0046130 112 0.018
antimicrobial humoral response GO:0019730 99 0.018
aromatic compound catabolic process GO:0019439 166 0.017
peptidyl amino acid modification GO:0018193 105 0.017
cell junction assembly GO:0034329 42 0.017
positive regulation of cellular component biogenesis GO:0044089 80 0.017
nucleoside phosphate catabolic process GO:1901292 110 0.017
response to alcohol GO:0097305 95 0.017
mesenchymal cell development GO:0014031 1 0.017
phosphorylation GO:0016310 294 0.017
organic acid metabolic process GO:0006082 103 0.017
myotube cell development GO:0014904 3 0.017
cell junction organization GO:0034330 57 0.017
nucleoside metabolic process GO:0009116 127 0.017
ribonucleoside triphosphate metabolic process GO:0009199 119 0.017
positive regulation of growth GO:0045927 75 0.016
ribonucleotide catabolic process GO:0009261 109 0.016
cellular response to decreased oxygen levels GO:0036294 30 0.016
cellular protein complex assembly GO:0043623 71 0.016
regulation of reproductive process GO:2000241 54 0.016
negative regulation of nervous system development GO:0051961 92 0.016
positive regulation of transport GO:0051050 92 0.016
purine nucleotide catabolic process GO:0006195 109 0.016
nucleoside triphosphate catabolic process GO:0009143 108 0.016
response to organic substance GO:0010033 284 0.016
single organism membrane organization GO:0044802 93 0.016
positive regulation of cell communication GO:0010647 250 0.016
ameboidal type cell migration GO:0001667 151 0.016
secondary metabolic process GO:0019748 75 0.016
positive regulation of signaling GO:0023056 243 0.016
phagocytosis GO:0006909 215 0.015
ensheathment of neurons GO:0007272 10 0.015
regulation of transmembrane transport GO:0034762 27 0.015
substrate adhesion dependent cell spreading GO:0034446 2 0.015
purine nucleoside triphosphate metabolic process GO:0009144 119 0.015
determination of adult lifespan GO:0008340 137 0.015
exocrine system development GO:0035272 162 0.015
reproductive system development GO:0061458 74 0.015
glycoprotein biosynthetic process GO:0009101 41 0.015
developmental growth involved in morphogenesis GO:0060560 65 0.015
epithelial cell migration open tracheal system GO:0007427 32 0.015
blastoderm segmentation GO:0007350 159 0.015
somatic muscle development GO:0007525 66 0.015
ribose phosphate metabolic process GO:0019693 145 0.015
heart morphogenesis GO:0003007 32 0.015
regulation of cellular amino acid metabolic process GO:0006521 0 0.015
regulation of cellular ketone metabolic process GO:0010565 3 0.015
regulation of lipid transport GO:0032368 3 0.014
regulation of catalytic activity GO:0050790 185 0.014
positive regulation of cell motility GO:2000147 3 0.014
r7 cell differentiation GO:0045466 43 0.014
cellular response to oxygen levels GO:0071453 30 0.014
purine nucleoside triphosphate catabolic process GO:0009146 108 0.014
telencephalon development GO:0021537 2 0.014
lymph gland development GO:0048542 28 0.014
protein phosphorylation GO:0006468 169 0.014
negative regulation of cell development GO:0010721 62 0.014
membrane organization GO:0061024 112 0.014
anatomical structure homeostasis GO:0060249 97 0.014
outflow tract morphogenesis GO:0003151 4 0.014
wing disc morphogenesis GO:0007472 344 0.014
terminal branching open tracheal system GO:0007430 17 0.014
sensory organ morphogenesis GO:0090596 260 0.014
columnar cuboidal epithelial cell development GO:0002066 249 0.014
maternal determination of anterior posterior axis embryo GO:0008358 74 0.014
salivary gland cell autophagic cell death GO:0035071 83 0.014
cognition GO:0050890 141 0.014
cell cycle arrest GO:0007050 4 0.014
positive regulation of cell migration GO:0030335 2 0.014
response to glucose GO:0009749 2 0.014
chitin based cuticle development GO:0040003 49 0.014
myoblast fusion GO:0007520 43 0.014
cellular component assembly involved in morphogenesis GO:0010927 151 0.014
purine containing compound catabolic process GO:0072523 112 0.013
cellular protein localization GO:0034613 160 0.013
response to hexose GO:0009746 3 0.013
germ line stem cell maintenance GO:0030718 50 0.013
ribonucleoside monophosphate biosynthetic process GO:0009156 3 0.013
monocarboxylic acid transport GO:0015718 3 0.013
protein complex assembly GO:0006461 200 0.013
cytoskeleton dependent cytokinesis GO:0061640 81 0.013
purine ribonucleoside triphosphate catabolic process GO:0009207 108 0.013
regulation of locomotion GO:0040012 42 0.013
regulation of neuron projection development GO:0010975 69 0.013
response to extracellular stimulus GO:0009991 116 0.013
response to peptide hormone GO:0043434 29 0.013
regulation of gene expression epigenetic GO:0040029 128 0.013
nucleoside catabolic process GO:0009164 112 0.013
innate immune response GO:0045087 144 0.013
ribonucleoside metabolic process GO:0009119 127 0.013
protein complex biogenesis GO:0070271 201 0.013
cell cell adhesion via plasma membrane adhesion molecules GO:0098742 26 0.012
compound eye cone cell fate commitment GO:0042676 5 0.012
negative regulation of gene expression GO:0010629 387 0.012
purine containing compound metabolic process GO:0072521 155 0.012
appendage morphogenesis GO:0035107 397 0.012
negative regulation of nucleobase containing compound metabolic process GO:0045934 261 0.012
cellular response to hypoxia GO:0071456 28 0.012
secretion GO:0046903 109 0.012
nucleocytoplasmic transport GO:0006913 72 0.012
negative regulation of nucleic acid templated transcription GO:1903507 240 0.012
guanosine containing compound catabolic process GO:1901069 74 0.012
smoothened signaling pathway GO:0007224 49 0.012
axon ensheathment GO:0008366 10 0.012
fluid transport GO:0042044 19 0.012
positive regulation of phosphate metabolic process GO:0045937 139 0.012
glycosyl compound metabolic process GO:1901657 127 0.012
compound eye photoreceptor cell differentiation GO:0001751 140 0.011
spermatogenesis GO:0007283 200 0.011
positive regulation of response to stimulus GO:0048584 323 0.011
regulation of cell substrate adhesion GO:0010810 2 0.011
positive regulation of cellular amine metabolic process GO:0033240 0 0.011
regulation of intracellular signal transduction GO:1902531 236 0.011
negative regulation of rna biosynthetic process GO:1902679 240 0.011
regulation of cell morphogenesis GO:0022604 163 0.011
positive regulation of neuron differentiation GO:0045666 26 0.011
neurological system process GO:0050877 358 0.011
salivary gland morphogenesis GO:0007435 145 0.011
reproductive structure development GO:0048608 74 0.011
positive regulation of mapk cascade GO:0043410 63 0.011
peptidyl threonine modification GO:0018210 3 0.011
photoreceptor cell differentiation GO:0046530 170 0.011
regulation of molecular function GO:0065009 217 0.011
single organism intracellular transport GO:1902582 207 0.011
carbohydrate derivative biosynthetic process GO:1901137 85 0.011
ocellus pigmentation GO:0033060 19 0.011
mapk cascade GO:0000165 107 0.011
histolysis GO:0007559 102 0.011
response to axon injury GO:0048678 12 0.011
regulation of programmed cell death GO:0043067 152 0.010
regulation of cell shape GO:0008360 113 0.010
nucleoside triphosphate metabolic process GO:0009141 120 0.010
response to organophosphorus GO:0046683 2 0.010
transmission of nerve impulse GO:0019226 12 0.010
cellular nitrogen compound catabolic process GO:0044270 165 0.010
protein secretion GO:0009306 45 0.010
meiotic chromosome segregation GO:0045132 59 0.010
hematopoietic or lymphoid organ development GO:0048534 57 0.010
response to growth factor GO:0070848 31 0.010
positive regulation of peptidyl tyrosine phosphorylation GO:0050731 4 0.010
positive regulation of phosphorus metabolic process GO:0010562 139 0.010
cellular response to acid chemical GO:0071229 8 0.010
response to calcium ion GO:0051592 1 0.010
protein targeting to nucleus GO:0044744 51 0.010

Ppn disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.414
musculoskeletal system disease DOID:17 0 0.188
connective tissue disease DOID:65 0 0.033
cardiovascular system disease DOID:1287 0 0.022
bone disease DOID:0080001 0 0.018
nervous system disease DOID:863 0 0.018
cancer DOID:162 0 0.012
disease of cellular proliferation DOID:14566 0 0.012