Drosophila melanogaster

63 known processes

Nsf2 (Dmel_CG33101)

NEM-sensitive fusion protein 2

(Aliases: dNsf2,dNSF-2,CG33101,NSF-2,Dmel\CG33101,dnsf2,NSF2,CG9931,Nsf-2,DmNSF2,dNSF2,dNSF)

Nsf2 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
synaptic transmission GO:0007268 288 0.918
respiratory system development GO:0060541 213 0.836
branching morphogenesis of an epithelial tube GO:0048754 45 0.772
organelle fusion GO:0048284 46 0.747
Yeast Fly
tube morphogenesis GO:0035239 191 0.738
establishment of localization in cell GO:0051649 402 0.699
Yeast Rat Worm Fly
epithelial tube morphogenesis GO:0060562 88 0.637
morphogenesis of a branching epithelium GO:0061138 45 0.591
establishment of synaptic vesicle localization GO:0097480 50 0.575
Fly
open tracheal system development GO:0007424 204 0.566
tube development GO:0035295 244 0.558
branching involved in open tracheal system development GO:0060446 45 0.556
synaptic vesicle transport GO:0048489 50 0.547
Fly
trachea development GO:0060438 29 0.488
chemotaxis GO:0006935 249 0.462
axon guidance GO:0007411 233 0.431
trachea morphogenesis GO:0060439 22 0.397
single organism membrane organization GO:0044802 93 0.391
Yeast Zebrafish Fly
vesicle mediated transport GO:0016192 381 0.387
Yeast Rat Worm Fly
axon development GO:0061564 297 0.380
Zebrafish
membrane fusion GO:0061025 42 0.345
Yeast Fly
neuromuscular synaptic transmission GO:0007274 67 0.321
tissue morphogenesis GO:0048729 297 0.302
regulation of localization GO:0032879 275 0.266
Rat Fly
axonogenesis GO:0007409 290 0.261
Zebrafish
morphogenesis of an epithelium GO:0002009 276 0.260
nucleoside triphosphate metabolic process GO:0009141 120 0.246
Yeast Mouse Rat Fly
synaptic vesicle localization GO:0097479 53 0.244
Fly
single organism membrane fusion GO:0044801 42 0.242
Yeast Fly
vesicle organization GO:0016050 44 0.229
Yeast Fly
morphogenesis of a branching structure GO:0001763 45 0.221
neurotransmitter secretion GO:0007269 35 0.218
Fly
vesicle localization GO:0051648 55 0.214
Zebrafish Fly
regionalization GO:0003002 416 0.205
terminal branching open tracheal system GO:0007430 17 0.205
exocytosis GO:0006887 28 0.196
Rat Fly
macromolecular complex assembly GO:0065003 256 0.185
Worm Fly
negative regulation of signaling GO:0023057 219 0.184
protein localization GO:0008104 284 0.179
Yeast Rat
cellular protein localization GO:0034613 160 0.171
Yeast
nuclear division GO:0000280 332 0.160
cytokinesis GO:0000910 90 0.154
regulation of transport GO:0051049 181 0.154
Rat Fly
negative regulation of signal transduction GO:0009968 206 0.144
regulation of cellular component biogenesis GO:0044087 201 0.144
organelle localization GO:0051640 148 0.136
Zebrafish Fly
cell division GO:0051301 248 0.134
multi organism behavior GO:0051705 175 0.131
organonitrogen compound metabolic process GO:1901564 318 0.122
Yeast Mouse Rat Fly
neuromuscular junction development GO:0007528 149 0.118
purine nucleoside triphosphate metabolic process GO:0009144 119 0.115
Yeast Mouse Rat Fly
intracellular transport GO:0046907 228 0.105
Yeast
vesicle fusion GO:0006906 19 0.103
Yeast Fly
endosomal transport GO:0016197 44 0.100
regulation of cellular localization GO:0060341 136 0.100
Rat
protein complex biogenesis GO:0070271 201 0.095
Worm Fly
ion transport GO:0006811 145 0.094
Mouse
nucleotide catabolic process GO:0009166 109 0.094
Yeast Mouse Rat Fly
cytoplasmic transport GO:0016482 130 0.094
Yeast
single organism intracellular transport GO:1902582 207 0.093
Yeast
carbohydrate derivative biosynthetic process GO:1901137 85 0.093
organophosphate metabolic process GO:0019637 195 0.091
Yeast Mouse Rat Fly
homeostatic process GO:0042592 199 0.088
positive regulation of cellular component organization GO:0051130 156 0.087
Fly
neuron projection guidance GO:0097485 241 0.087
endocytosis GO:0006897 310 0.087
Worm Fly
establishment of vesicle localization GO:0051650 51 0.086
Fly
taxis GO:0042330 304 0.086
regulation of multicellular organismal development GO:2000026 414 0.083
negative regulation of response to stimulus GO:0048585 258 0.078
glycosyl compound metabolic process GO:1901657 127 0.076
Yeast Mouse Rat Fly
larval development GO:0002164 104 0.076
Worm
purine ribonucleoside triphosphate metabolic process GO:0009205 119 0.073
Yeast Mouse Rat Fly
blastoderm segmentation GO:0007350 159 0.073
ribonucleoside metabolic process GO:0009119 127 0.073
Yeast Mouse Rat Fly
protein transport GO:0015031 155 0.072
Yeast Rat
purine nucleoside triphosphate catabolic process GO:0009146 108 0.071
Yeast Mouse Rat Fly
secretion GO:0046903 109 0.070
Rat Worm Fly
actin filament based process GO:0030029 220 0.070
Worm
organic substance catabolic process GO:1901575 308 0.069
Yeast Mouse Rat Fly
organonitrogen compound catabolic process GO:1901565 128 0.069
Yeast Mouse Rat Fly
regulation of anatomical structure morphogenesis GO:0022603 242 0.068
purine ribonucleoside catabolic process GO:0046130 112 0.066
Yeast Mouse Rat Fly
positive regulation of axonogenesis GO:0050772 2 0.065
neurotransmitter transport GO:0006836 37 0.065
Fly
intracellular signal transduction GO:0035556 300 0.064
phagocytosis GO:0006909 215 0.063
Fly
epithelial cell differentiation GO:0030855 322 0.063
response to other organism GO:0051707 293 0.063
positive regulation of cell migration GO:0030335 2 0.062
organelle fission GO:0048285 340 0.062
mitotic cytokinesis GO:0000281 50 0.060
body morphogenesis GO:0010171 2 0.059
single organism biosynthetic process GO:0044711 206 0.058
cellular macromolecular complex assembly GO:0034622 153 0.058
Worm
single organism catabolic process GO:0044712 228 0.058
Yeast Mouse Rat Fly
segmentation GO:0035282 207 0.058
cell migration GO:0016477 238 0.057
purine nucleotide metabolic process GO:0006163 146 0.056
Yeast Mouse Rat Fly
dorsal ventral pattern formation GO:0009953 133 0.055
secretion by cell GO:0032940 101 0.055
Rat Worm Fly
divalent inorganic cation transport GO:0072511 30 0.055
cell death GO:0008219 279 0.055
Worm
ameboidal type cell migration GO:0001667 151 0.055
carbohydrate derivative metabolic process GO:1901135 217 0.054
Yeast Mouse Rat Fly
carbohydrate derivative catabolic process GO:1901136 118 0.053
Yeast Mouse Rat Fly
membrane organization GO:0061024 112 0.053
Yeast Zebrafish Fly
epithelial cell migration GO:0010631 148 0.053
central nervous system development GO:0007417 201 0.052
Zebrafish
embryo development ending in birth or egg hatching GO:0009792 152 0.051
Worm
cellular amide metabolic process GO:0043603 80 0.051
single organism cellular localization GO:1902580 180 0.051
Yeast
mesenchymal cell differentiation GO:0048762 1 0.051
regulation of protein metabolic process GO:0051246 256 0.050
purine ribonucleoside metabolic process GO:0046128 127 0.050
Yeast Mouse Rat Fly
negative regulation of cell communication GO:0010648 223 0.050
positive regulation of macromolecule metabolic process GO:0010604 405 0.050
Human
protein complex assembly GO:0006461 200 0.049
Worm Fly
nucleotide metabolic process GO:0009117 161 0.049
Yeast Mouse Rat Fly
purine nucleotide catabolic process GO:0006195 109 0.049
Yeast Mouse Rat Fly
purine containing compound catabolic process GO:0072523 112 0.049
Yeast Mouse Rat Fly
locomotory behavior GO:0007626 176 0.049
cellular homeostasis GO:0019725 80 0.048
cytoskeleton dependent cytokinesis GO:0061640 81 0.048
organic substance transport GO:0071702 257 0.048
Yeast Rat
regulation of notch signaling pathway GO:0008593 100 0.048
response to biotic stimulus GO:0009607 294 0.048
mating behavior GO:0007617 106 0.047
synaptic vesicle recycling GO:0036465 28 0.047
cell proliferation GO:0008283 299 0.047
response to external biotic stimulus GO:0043207 293 0.046
actin cytoskeleton organization GO:0030036 206 0.046
Worm
small molecule metabolic process GO:0044281 305 0.046
Yeast Mouse Rat Fly
meiotic cytokinesis GO:0033206 33 0.045
catabolic process GO:0009056 409 0.044
Yeast Mouse Rat Fly
synaptic vesicle exocytosis GO:0016079 16 0.043
Fly
establishment of protein localization GO:0045184 163 0.042
Yeast Rat
head development GO:0060322 135 0.041
Zebrafish
ribonucleoside triphosphate catabolic process GO:0009203 108 0.041
Yeast Mouse Rat Fly
phosphorylation GO:0016310 294 0.040
multicellular organismal reproductive behavior GO:0033057 110 0.040
positive regulation of nitrogen compound metabolic process GO:0051173 354 0.039
regulation of synaptic transmission GO:0050804 69 0.039
Fly
guanosine containing compound metabolic process GO:1901068 74 0.038
oocyte differentiation GO:0009994 145 0.038
regulation of reproductive process GO:2000241 54 0.038
positive regulation of cellular component biogenesis GO:0044089 80 0.038
regulation of intracellular transport GO:0032386 64 0.038
regulation of microtubule based process GO:0032886 49 0.038
multi organism reproductive behavior GO:0044705 121 0.038
regulation of locomotion GO:0040012 42 0.037
regulation of cell morphogenesis involved in differentiation GO:0010769 61 0.037
regulation of organelle organization GO:0033043 196 0.037
nucleoside triphosphate catabolic process GO:0009143 108 0.037
Yeast Mouse Rat Fly
negative regulation of gene expression GO:0010629 387 0.037
microtubule cytoskeleton organization involved in mitosis GO:1902850 52 0.036
organophosphate catabolic process GO:0046434 112 0.036
Yeast Mouse Rat Fly
regulation of multi organism process GO:0043900 131 0.036
regulation of cell development GO:0060284 215 0.036
regulation of cellular catabolic process GO:0031329 157 0.035
autophagy GO:0006914 108 0.035
Yeast
meiotic cell cycle GO:0051321 171 0.035
anatomical structure homeostasis GO:0060249 97 0.033
regulation of cell projection organization GO:0031344 92 0.033
nucleoside catabolic process GO:0009164 112 0.033
Yeast Mouse Rat Fly
regulation of cell cycle GO:0051726 291 0.033
mitotic nuclear division GO:0007067 213 0.033
cellular lipid metabolic process GO:0044255 83 0.033
ribonucleotide catabolic process GO:0009261 109 0.033
Yeast Mouse Rat Fly
glycosyl compound catabolic process GO:1901658 112 0.033
Yeast Mouse Rat Fly
purine nucleoside metabolic process GO:0042278 127 0.032
Yeast Mouse Rat Fly
anterior posterior axis specification embryo GO:0008595 103 0.032
reproductive behavior GO:0019098 122 0.032
establishment or maintenance of cell polarity GO:0007163 167 0.032
male meiosis cytokinesis GO:0007112 26 0.031
defense response GO:0006952 300 0.031
cell motility GO:0048870 251 0.030
ovarian follicle cell development GO:0030707 248 0.030
positive regulation of cell development GO:0010720 61 0.030
positive regulation of response to stimulus GO:0048584 323 0.030
regulation of protein localization GO:0032880 76 0.030
regulation of vesicle mediated transport GO:0060627 59 0.029
Rat Fly
purine containing compound metabolic process GO:0072521 155 0.029
Yeast Mouse Rat Fly
embryonic pattern specification GO:0009880 174 0.029
positive regulation of transcription dna templated GO:0045893 266 0.029
regulation of pathway restricted smad protein phosphorylation GO:0060393 1 0.029
negative regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090101 18 0.029
epithelial cell development GO:0002064 274 0.029
forebrain development GO:0030900 2 0.028
Zebrafish
purine ribonucleotide metabolic process GO:0009150 145 0.028
Yeast Mouse Rat Fly
protein modification process GO:0036211 438 0.028
cell cell signaling involved in cell fate commitment GO:0045168 210 0.028
lipid metabolic process GO:0006629 121 0.027
regulation of immune system process GO:0002682 176 0.027
cellular macromolecule localization GO:0070727 220 0.027
Yeast
regulation of phosphorus metabolic process GO:0051174 210 0.027
positive regulation of nucleobase containing compound metabolic process GO:0045935 332 0.026
lateral inhibition GO:0046331 206 0.026
embryonic axis specification GO:0000578 107 0.026
regulation of neuron death GO:1901214 26 0.026
cellular protein complex assembly GO:0043623 71 0.026
Worm
brain development GO:0007420 120 0.026
Zebrafish
mesenchymal cell development GO:0014031 1 0.025
regulation of establishment of protein localization GO:0070201 61 0.025
stem cell development GO:0048864 79 0.025
regulation of neuron differentiation GO:0045664 103 0.025
muscle structure development GO:0061061 224 0.025
Worm
notch signaling pathway GO:0007219 120 0.025
cation transport GO:0006812 110 0.025
Mouse
camera type eye development GO:0043010 4 0.025
spindle assembly GO:0051225 80 0.024
defense response to other organism GO:0098542 225 0.024
positive regulation of neurogenesis GO:0050769 41 0.023
regulation of cytoplasmic transport GO:1903649 47 0.023
response to extracellular stimulus GO:0009991 116 0.023
Yeast
striated muscle cell differentiation GO:0051146 90 0.023
Worm
nucleoside metabolic process GO:0009116 127 0.023
Yeast Mouse Rat Fly
spindle organization GO:0007051 253 0.023
wing disc pattern formation GO:0035222 66 0.023
cellular ion homeostasis GO:0006873 39 0.022
positive regulation of nucleic acid templated transcription GO:1903508 266 0.022
synaptic vesicle endocytosis GO:0048488 28 0.022
nucleobase containing small molecule metabolic process GO:0055086 174 0.022
Yeast Mouse Rat Fly
anion transport GO:0006820 41 0.022
appendage development GO:0048736 401 0.022
synaptic vesicle priming GO:0016082 1 0.022
regulation of intracellular protein transport GO:0033157 46 0.022
male mating behavior GO:0060179 70 0.021
metal ion transport GO:0030001 74 0.021
Mouse
cellular protein modification process GO:0006464 438 0.021
response to nutrient levels GO:0031667 114 0.020
Yeast
imaginal disc growth GO:0007446 37 0.020
positive regulation of gene expression GO:0010628 290 0.020
cellular response to starvation GO:0009267 61 0.020
Yeast
regulation of gtp catabolic process GO:0033124 44 0.020
programmed cell death GO:0012501 257 0.020
Worm
organelle assembly GO:0070925 198 0.020
Yeast Worm
chemical homeostasis GO:0048878 92 0.019
protein maturation GO:0051604 71 0.019
columnar cuboidal epithelial cell development GO:0002066 249 0.019
positive regulation of cell projection organization GO:0031346 29 0.019
regulation of protein transport GO:0051223 57 0.019
retina development in camera type eye GO:0060041 4 0.019
protein phosphorylation GO:0006468 169 0.019
regulation of cell differentiation GO:0045595 302 0.019
multi multicellular organism process GO:0044706 123 0.019
regulation of molecular function GO:0065009 217 0.018
ion homeostasis GO:0050801 55 0.018
nucleoside phosphate metabolic process GO:0006753 162 0.018
Yeast Mouse Rat Fly
growth GO:0040007 359 0.018
tripartite regional subdivision GO:0007351 103 0.018
negative regulation of mitotic cell cycle GO:0045930 109 0.018
positive regulation of cell death GO:0010942 69 0.018
ribose phosphate metabolic process GO:0019693 145 0.018
Yeast Mouse Rat Fly
negative regulation of cellular component organization GO:0051129 108 0.017
establishment of organelle localization GO:0051656 122 0.017
Fly
regulation of imaginal disc growth GO:0045570 26 0.017
lamellipodium organization GO:0097581 21 0.017
determination of adult lifespan GO:0008340 137 0.017
localization of cell GO:0051674 257 0.017
embryonic development via the syncytial blastoderm GO:0001700 148 0.017
regulation of epithelial cell proliferation GO:0050678 4 0.017
organ growth GO:0035265 56 0.016
connective tissue development GO:0061448 3 0.016
carbohydrate biosynthetic process GO:0016051 17 0.016
regulation of purine nucleotide metabolic process GO:1900542 62 0.016
compound eye development GO:0048749 307 0.016
positive regulation of developmental process GO:0051094 143 0.016
retrograde transport endosome to golgi GO:0042147 3 0.016
purine ribonucleoside triphosphate catabolic process GO:0009207 108 0.016
Yeast Mouse Rat Fly
imaginal disc pattern formation GO:0007447 91 0.016
oocyte development GO:0048599 124 0.016
feeding behavior GO:0007631 50 0.016
stem cell differentiation GO:0048863 117 0.015
photoreceptor cell differentiation GO:0046530 170 0.015
regulation of nucleoside metabolic process GO:0009118 50 0.015
regulation of axonogenesis GO:0050770 32 0.015
transmembrane transport GO:0055085 139 0.015
centriole replication GO:0007099 24 0.015
cellular cation homeostasis GO:0030003 38 0.015
cation homeostasis GO:0055080 51 0.015
regulation of mitotic cell cycle GO:0007346 190 0.015
positive regulation of catalytic activity GO:0043085 118 0.015
regulation of cellular protein metabolic process GO:0032268 243 0.015
defense response to gram negative bacterium GO:0050829 94 0.015
carbohydrate metabolic process GO:0005975 82 0.015
meiotic cell cycle process GO:1903046 132 0.015
receptor mediated endocytosis GO:0006898 21 0.015
Worm
developmental growth GO:0048589 280 0.015
negative regulation of growth GO:0045926 84 0.015
somatic muscle development GO:0007525 66 0.015
cuticle development GO:0042335 86 0.014
multicellular organismal aging GO:0010259 140 0.014
purine ribonucleotide catabolic process GO:0009154 109 0.014
Yeast Mouse Rat Fly
neuron neuron synaptic transmission GO:0007270 14 0.014
smoothened signaling pathway GO:0007224 49 0.014
negative regulation of developmental process GO:0051093 201 0.014
immune response regulating signaling pathway GO:0002764 2 0.014
ribonucleotide metabolic process GO:0009259 145 0.014
Yeast Mouse Rat Fly
neuron death GO:0070997 27 0.014
limb development GO:0060173 1 0.014
heterocycle catabolic process GO:0046700 166 0.014
Yeast Mouse Rat Fly
regulation of phosphate metabolic process GO:0019220 210 0.014
protein modification by small protein conjugation or removal GO:0070647 106 0.014
regulation of cytoskeleton organization GO:0051493 89 0.014
positive regulation of phosphate metabolic process GO:0045937 139 0.014
memory GO:0007613 94 0.014
rna localization GO:0006403 115 0.014
regulation of cellular response to growth factor stimulus GO:0090287 13 0.014
enzyme linked receptor protein signaling pathway GO:0007167 179 0.014
regulation of response to external stimulus GO:0032101 115 0.014
mating GO:0007618 120 0.014
regulation of embryonic development GO:0045995 68 0.013
regulation of cellular component size GO:0032535 98 0.013
positive regulation of cell communication GO:0010647 250 0.013
regulation of neurotransmitter levels GO:0001505 38 0.013
Fly
rna processing GO:0006396 147 0.013
germ cell migration GO:0008354 43 0.013
appendage morphogenesis GO:0035107 397 0.013
response to radiation GO:0009314 155 0.013
apoptotic process GO:0006915 159 0.013
Worm
positive regulation of transport GO:0051050 92 0.013
Fly
maternal determination of anterior posterior axis embryo GO:0008358 74 0.013
cellular response to chemical stimulus GO:0070887 199 0.013
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 65 0.013
regulation of cellular component movement GO:0051270 42 0.013
centriole assembly GO:0098534 24 0.013
protein import into nucleus GO:0006606 51 0.013
protein localization to membrane GO:0072657 19 0.013
Yeast
regulation of nucleotide metabolic process GO:0006140 62 0.012
developmental maturation GO:0021700 172 0.012
Zebrafish
positive regulation of nervous system development GO:0051962 69 0.012
positive regulation of axon extension GO:0045773 2 0.012
posttranscriptional regulation of gene expression GO:0010608 145 0.012
organic cyclic compound catabolic process GO:1901361 168 0.012
Yeast Mouse Rat Fly
cellular component assembly involved in morphogenesis GO:0010927 151 0.012
Worm
regulation of cell morphogenesis GO:0022604 163 0.012
transcription from rna polymerase ii promoter GO:0006366 368 0.012
organonitrogen compound biosynthetic process GO:1901566 117 0.012
biological adhesion GO:0022610 138 0.012
oocyte construction GO:0007308 112 0.012
positive regulation of signal transduction GO:0009967 223 0.012
imaginal disc derived appendage morphogenesis GO:0035114 395 0.012
response to bacterium GO:0009617 198 0.012
negative regulation of phosphate metabolic process GO:0045936 45 0.012
nucleus organization GO:0006997 45 0.012
regulation of nucleotide catabolic process GO:0030811 48 0.012
axon extension GO:0048675 32 0.012
negative regulation of synaptic growth at neuromuscular junction GO:0045886 39 0.012
regulation of epithelial cell migration GO:0010632 12 0.012
neuron apoptotic process GO:0051402 17 0.012
nitrogen compound transport GO:0071705 85 0.012
response to hypoxia GO:0001666 53 0.012
myotube differentiation GO:0014902 46 0.011
regulation of protein complex assembly GO:0043254 42 0.011
embryonic organ development GO:0048568 50 0.011
divalent metal ion transport GO:0070838 26 0.011
positive regulation of cell motility GO:2000147 3 0.011
cellular chemical homeostasis GO:0055082 40 0.011
ion transmembrane transport GO:0034220 122 0.011
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 116 0.011
protein polymerization GO:0051258 42 0.011
chorion containing eggshell formation GO:0007304 105 0.011
tissue migration GO:0090130 155 0.011
regulation of transcription from rna polymerase ii promoter GO:0006357 378 0.011
regulation of cell cycle process GO:0010564 181 0.011
negative regulation of cellular protein metabolic process GO:0032269 85 0.011
protein processing GO:0016485 68 0.011
dendrite development GO:0016358 204 0.011
synapse organization GO:0050808 196 0.010
negative regulation of phosphorus metabolic process GO:0010563 45 0.010
regulation of behavior GO:0050795 75 0.010
inorganic ion transmembrane transport GO:0098660 73 0.010
developmental cell growth GO:0048588 52 0.010
mitochondrion organization GO:0007005 65 0.010
eye development GO:0001654 323 0.010
Zebrafish
protein catabolic process GO:0030163 101 0.010
cellular response to decreased oxygen levels GO:0036294 30 0.010
regulation of cell death GO:0010941 173 0.010
aging GO:0007568 143 0.010
oocyte anterior posterior axis specification GO:0007314 72 0.010

Nsf2 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.047
cardiovascular system disease DOID:1287 0 0.047
artery disease DOID:0050828 0 0.022
vascular disease DOID:178 0 0.022
disease of mental health DOID:150 0 0.015
developmental disorder of mental health DOID:0060037 0 0.015
specific developmental disorder DOID:0060038 0 0.015
intellectual disability DOID:1059 0 0.015
non syndromic intellectual disability DOID:0050889 0 0.013